LOCUS       DAVBIC010000001        80116 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.001, whole genome shotgun sequence.
ACCESSION   DAVBIC010000001 DAVBIC010000000
VERSION     DAVBIC010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 80116)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 80116)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..80116
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.001"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            complement(134..1882)
                     /locus_tag="VQ664_000001"
     CDS             complement(134..1882)
                     /locus_tag="VQ664_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2788256.1"
                     /translation="MKRQTVNQTLKRLVVDLANHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFADRQGNGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKRSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGST
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     SDQVKGAISFKHVSFGYHPEKILIKELSIDIPAGSKVAIVGPTGAGKSTLINLLMRFY
                     PISSGDILLDGQSIYDYTRVSLRQQFGMVLQETWLTQGTIHDNIAFGNPEASREQVIA
                     AAKAANADFFIQQLPQGYDTKLENAGESLSVGQAQLLTISRVFLAIPKILILDEATSS
                     IDTRTEVLVQDAFAKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMDR
                     KGKYYQMQKAAAFSSE"
     gene            complement(1884..3608)
                     /locus_tag="VQ664_000002"
     CDS             complement(1884..3608)
                     /locus_tag="VQ664_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2788257.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLPKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISAELTFWFL
                     VMVAILTIVIVGLSRLVNPLYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFLSSLLTPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISAKRIEEVFAESPENIHSELEQKQVTSGRVLQV
                     QELTFTYPDAAQPSLRDISFDMTQGQILGIIGGTGSGKSSLVQLLLGLYPVDKGNIDL
                     YQNGRSPLNLEQWRSWIAYVPQKVELFKGTIRSNLTLGLNQEVTDQELWQALEIAQAK
                     DFVSDKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFLILDDATSALDTITESK
                     LLKAIRENLPNMSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYREIN
                     ASQHGKED"
     gene            complement(3666..4604)
                     /gene="msrB"
                     /locus_tag="VQ664_000003"
     CDS             complement(3666..4604)
                     /gene="msrB"
                     /locus_tag="VQ664_000003"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HET2788258.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLI
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            complement(4746..4823)
                     /locus_tag="VQ664_000004"
                     /pseudo
     CDS             complement(4746..4823)
                     /locus_tag="VQ664_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(4899..5768)
                     /locus_tag="VQ664_000005"
     CDS             complement(4899..5768)
                     /locus_tag="VQ664_000005"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HET2788259.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTKGVRVEAK"
     gene            complement(5770..7056)
                     /locus_tag="VQ664_000006"
     CDS             complement(5770..7056)
                     /locus_tag="VQ664_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HET2788260.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVAHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILALDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            complement(7207..7944)
                     /gene="mecA"
                     /locus_tag="VQ664_000007"
     CDS             complement(7207..7944)
                     /gene="mecA"
                     /locus_tag="VQ664_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HET2788261.1"
                     /translation="MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVAFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            complement(8144..9178)
                     /locus_tag="VQ664_000008"
     CDS             complement(8144..9178)
                     /locus_tag="VQ664_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HET2788262.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPKESAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            complement(9207..10640)
                     /locus_tag="VQ664_000009"
     CDS             complement(9207..10640)
                     /locus_tag="VQ664_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HET2788263.1"
                     /translation="MIDGKRLLFSLTIVSYALTLVSGIVYLFNNNNVSLLSTLLFLLV
                     SSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMV
                     SILGLTTGGILARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQTEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQFWGIVLVIIFIAKMLTKEN"
     gene            complement(10656..11642)
                     /locus_tag="VQ664_000010"
     CDS             complement(10656..11642)
                     /locus_tag="VQ664_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET2788264.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQIYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATALSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAEKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGHAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            complement(11644..12747)
                     /locus_tag="VQ664_000011"
     CDS             complement(11644..12747)
                     /locus_tag="VQ664_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HET2788265.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDLEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLTRRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYASKLQIIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYGIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTDVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFDVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            complement(12737..13582)
                     /locus_tag="VQ664_000012"
     CDS             complement(12737..13582)
                     /locus_tag="VQ664_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HET2788266.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLLCYLCGGGAIGALR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSHKDFVDRNLFITIRDKET
                     TCIKPYQQDLDLPHGLTLDVLPLDYYPKNPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSRILLGLTPKSLRYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKQVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            complement(13861..15135)
                     /gene="psr"
                     /locus_tag="VQ664_000013"
     CDS             complement(13861..15135)
                     /gene="psr"
                     /locus_tag="VQ664_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HET2788267.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFAYLQEKLTLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSFPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            complement(15132..15980)
                     /gene="pheA"
                     /locus_tag="VQ664_000014"
     CDS             complement(15132..15980)
                     /gene="pheA"
                     /locus_tag="VQ664_000014"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HET2788268.1"
                     /translation="MKIAYLGPKGSFSHHVVQTAFPHEELQAFANITDVIKAYEQGLV
                     DYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAVAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWVLGAEKPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYIDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            complement(15977..16453)
                     /locus_tag="VQ664_000015"
     CDS             complement(15977..16453)
                     /locus_tag="VQ664_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HET2788269.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGMSIANFFA
                     EKGEAAFRHVESEVLADLLQTDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     LRIAADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            complement(16446..17729)
                     /gene="aroA"
                     /locus_tag="VQ664_000016"
     CDS             complement(16446..17729)
                     /gene="aroA"
                     /locus_tag="VQ664_000016"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HET2788270.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITIQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLRPIHY
                     ELPIASAQVKSALMFAALQAKGESVIIEKEYTRNHTEDMLQQFGGHLSVDGKKITVQG
                     PQKLTGQKVVVPGDISSAAFWLVAGLIAPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EITEIDPVAKSATLIVESSDLKGTEIGGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            complement(17821..18159)
                     /locus_tag="VQ664_000017"
     CDS             complement(17821..18159)
                     /locus_tag="VQ664_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HET2788271.1"
                     /translation="MSNIYDSANELSRGLRGLPEYKAVKAAKDAIAADAEASKIFTEY
                     LAFQEEIQKLAQTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            complement(18170..19273)
                     /locus_tag="VQ664_000018"
     CDS             complement(18170..19273)
                     /locus_tag="VQ664_000018"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HET2788272.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSETILDRIEDFKERLEVIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITENTDYTVVIK"
     gene            complement(19283..20449)
                     /gene="aroC"
                     /locus_tag="VQ664_000019"
     CDS             complement(19283..20449)
                     /gene="aroC"
                     /locus_tag="VQ664_000019"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HET2788273.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIESDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            complement(20459..21526)
                     /locus_tag="VQ664_000020"
     CDS             complement(20459..21526)
                     /locus_tag="VQ664_000020"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HET2788274.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     VAEEKGLMPAGITQSITEMCQKFGLPVDYENWKVDKLYQALTHDKKARGNTLKLVLVP
                     ELGSATIHPVSLEEMKDYLVK"
     gene            complement(21545..22399)
                     /locus_tag="VQ664_000021"
     CDS             complement(21545..22399)
                     /locus_tag="VQ664_000021"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HET2788275.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGAYVAWEI
                     EASDLVETVANIRRYQMFGINLSMPYKEQVIPYLDELSDEARLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQSSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKKMPTEEIW
                     QSLTEKYQ"
     gene            complement(22389..23066)
                     /locus_tag="VQ664_000022"
     CDS             complement(22389..23066)
                     /locus_tag="VQ664_000022"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HET2788276.1"
                     /translation="MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQLYQPDYIDFEYYSYKD
                     VFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            complement(23063..24226)
                     /locus_tag="VQ664_000023"
     CDS             complement(23063..24226)
                     /locus_tag="VQ664_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HET2788277.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFVSKDKVAFNQAFFETLFRKAKEKRNAYYQDDLTTAFRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGLDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLAMGKSLLN
                     MFSYTAAFSVAAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDERRFIVMDVFEYF
                     KYAKRKNLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            complement(24911..26545)
                     /locus_tag="VQ664_000024"
                     /pseudo
     CDS             complement(24911..26545)
                     /locus_tag="VQ664_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(26526..27275)
                     /locus_tag="VQ664_000025"
     CDS             complement(26526..27275)
                     /locus_tag="VQ664_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2788278.1"
                     /translation="MIEFQNVSKLYGDKEALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLTSSDLETSLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSAPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCDRIAILKKGHLIYCGSVEN
                     LRKDHPDQFLESIYLSLAGRKEEVADASQGH"
     gene            27454..28908
                     /locus_tag="VQ664_000026"
     CDS             27454..28908
                     /locus_tag="VQ664_000026"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HET2788279.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAENAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKEQGIQPMADVVL
                     NHKAAADNREAFQVIEVDPVDRTVELGEPFTINGWTSFTFDGRQDTYNGFHWHWYHFT
                     GTDYDAKRSKSGIYLIQGDNKGWANEELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKAVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQEDFKEILDRLLAIR
                     KDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            complement(28998..31616)
                     /gene="alaS"
                     /locus_tag="VQ664_000027"
     CDS             complement(28998..31616)
                     /gene="alaS"
                     /locus_tag="VQ664_000027"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HET2788280.1"
                     /translation="MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLISPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGS
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNYNTSQLSSKLVAIVADNAEVGAVSEGTASLIFAETSFYAEMGGQVA
                     DYGQILDESGKIVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLAIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVGNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAVAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDAKEVNGHRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGS
                     NQAKIQELLDAVAGKL"
     gene            complement(31638..32123)
                     /locus_tag="VQ664_000028"
     CDS             complement(31638..32123)
                     /locus_tag="VQ664_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related family protein"
                     /protein_id="HET2788281.1"
                     /translation="MKTFLVKQKFRLGGERFAIKDDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSQISKEILTLLPRFEIQLLDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            complement(32398..32637)
                     /locus_tag="VQ664_000029"
     CDS             complement(32398..32637)
                     /locus_tag="VQ664_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2788282.1"
                     /translation="MKMSTFFNKSFWPTFMIVNQTAILFHLKDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILEK"
     gene            complement(32890..33960)
                     /locus_tag="VQ664_000030"
     CDS             complement(32890..33960)
                     /locus_tag="VQ664_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET2788283.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYETFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIEGIENIGPEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKPEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDLQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQDS
                     AYAFINFMLKPENALQNAEYVGYSTPNIPAKELLPEETKEDKAFYPDVETMKHLEIYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            complement(33957..34730)
                     /locus_tag="VQ664_000031"
     CDS             complement(33957..34730)
                     /locus_tag="VQ664_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2788284.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLILAQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIITGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            complement(34727..35533)
                     /locus_tag="VQ664_000032"
     CDS             complement(34727..35533)
                     /locus_tag="VQ664_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2788285.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWLMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            complement(35514..36671)
                     /locus_tag="VQ664_000033"
     CDS             complement(35514..36671)
                     /locus_tag="VQ664_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2788286.1"
                     /translation="MKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRKIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFESEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            complement(36730..37680)
                     /gene="murB"
                     /locus_tag="VQ664_000034"
     CDS             complement(36730..37680)
                     /gene="murB"
                     /locus_tag="VQ664_000034"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HET2788287.1"
                     /translation="MSVREKMLEILEGIDIRFQEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARLVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESLSVAKMYAGGFTPCKR"
     gene            complement(37792..38544)
                     /locus_tag="VQ664_000035"
     CDS             complement(37792..38544)
                     /locus_tag="VQ664_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
                     /protein_id="HET2788288.1"
                     /translation="MTIHIIITMLLLLAFLIGSIWFAKKKYQINLAVLGLGAVAFFVS
                     SQILEKLVHILILHPQKDGSIALLQDHPLIYIIYGLAMAAFFEETARLVFFKWFEKKR
                     SLEKADALAYGLGHGGLELIFLGLTSLLNLYIVLSAVQTQNPQVMQLLSENMLKTIQS
                     LSVWQIYLLGFERILALGFQLLLTVWVYQAVRQKKWIYLLTAYGLHAFFDLAPSLFQV
                     GWLTNPVLVEVILALELVLVAYGTKEIFCKKS"
     gene            complement(38554..39285)
                     /gene="budA"
                     /locus_tag="VQ664_000036"
     CDS             complement(38554..39285)
                     /gene="budA"
                     /locus_tag="VQ664_000036"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HET2788289.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKGSGDQPEIVEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELKERIESYYDGENLFRSIKIRGEFLHMHVRMIPKSTPDTKFADVATHQPEYSRDNV
                     AGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            39427..40698
                     /locus_tag="VQ664_000037"
     CDS             39427..40698
                     /locus_tag="VQ664_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HET2788290.1"
                     /translation="MKKQSKYKEVVSYLKNGIESGRFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFEQALYCKANQLVLTSGTQQALFILSQISFP
                     RQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRSILNLAAKYDVYIVEDDYLGDLDSKKGQTFHYLDTEEHVIYI
                     KSFSTSLFPALRITALILPNAIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQLGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            complement(40718..41533)
                     /locus_tag="VQ664_000038"
     CDS             complement(40718..41533)
                     /locus_tag="VQ664_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HET2788291.1"
                     /translation="MKSKKWIFVLCNFLASFFLVACQSGSNGSQSAVEAIKQKGKLVV
                     ATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEILSMSFDNVLTSLQTGK
                     ADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTSLESANIAAQKGT
                     VPESMVKEQLPKAQLTSLTNMGEAVNELQAGKIDAVHMDEPVALSYAAKNAGLAVATV
                     SLKMKDGDANAVALRKNSDDLKEVVDKVIQKLKDEGTYQSYLEKAASLTEVEE"
     gene            complement(41690..42343)
                     /gene="phoU"
                     /locus_tag="VQ664_000039"
     CDS             complement(41690..42343)
                     /gene="phoU"
                     /locus_tag="VQ664_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HET2788292.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            complement(42355..43113)
                     /gene="pstB"
                     /locus_tag="VQ664_000040"
     CDS             complement(42355..43113)
                     /gene="pstB"
                     /locus_tag="VQ664_000040"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HET2788293.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLDPQHKETEDYITGKFG"
     gene            complement(43126..43929)
                     /gene="pstB"
                     /locus_tag="VQ664_000041"
     CDS             complement(43126..43929)
                     /gene="pstB"
                     /locus_tag="VQ664_000041"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HET2788294.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            complement(43940..44824)
                     /gene="pstA"
                     /locus_tag="VQ664_000042"
     CDS             complement(43940..44824)
                     /gene="pstA"
                     /locus_tag="VQ664_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HET2788295.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            complement(44814..45731)
                     /gene="pstC"
                     /locus_tag="VQ664_000043"
     CDS             complement(44814..45731)
                     /gene="pstC"
                     /locus_tag="VQ664_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HET2788296.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGTWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            complement(45731..46609)
                     /gene="pstS"
                     /locus_tag="VQ664_000044"
     CDS             complement(45731..46609)
                     /gene="pstS"
                     /locus_tag="VQ664_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HET2788297.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            complement(47183..48487)
                     /locus_tag="VQ664_000045"
     CDS             complement(47183..48487)
                     /locus_tag="VQ664_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HET2788298.1"
                     /translation="MKFPEGFVEKYKEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGRLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQIFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKPSQVEQSVEIGQEEFVKYAAGET
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            complement(48488..49261)
                     /locus_tag="VQ664_000046"
     CDS             complement(48488..49261)
                     /locus_tag="VQ664_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HET2788299.1"
                     /translation="MKSKFEFAKELVKKAGQYILDHMQEDLRVETKSSPTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRPLASFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRAVLGVRVYGSAAISFAKILSGRLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            complement(49251..49529)
                     /locus_tag="VQ664_000047"
     CDS             complement(49251..49529)
                     /locus_tag="VQ664_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HET2788300.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGKGKISLEK"
     gene            complement(49529..49930)
                     /locus_tag="VQ664_000048"
     CDS             complement(49529..49930)
                     /locus_tag="VQ664_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HET2788301.1"
                     /translation="MITLFLSPSCTSCRKAKTWLEKHKVPFVEHNIMTSPLTRKELQH
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            complement(50140..50757)
                     /locus_tag="VQ664_000049"
     CDS             complement(50140..50757)
                     /locus_tag="VQ664_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HET2788302.1"
                     /translation="MKTKLTFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLALVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYESFFGYLCLKSRRK"
     gene            complement(50747..51520)
                     /locus_tag="VQ664_000050"
     CDS             complement(50747..51520)
                     /locus_tag="VQ664_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HET2788303.1"
                     /translation="MKYKGYLIDLDGTIYKGKDQIPAGETFVHELQKRDIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEDKEKPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            complement(51531..52268)
                     /locus_tag="VQ664_000051"
     CDS             complement(51531..52268)
                     /locus_tag="VQ664_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000524807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HET2788304.1"
                     /translation="MGLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEDYNLVWIIVEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAGQ
                     ELIHMMATFVLMDRDSRKVHAVEPEIVAPYQSDFDKKLIRGPKYESLEESISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSAVERTG
                     LESKHEITSDGVINAQAIITWQEIKKA"
     gene            complement(52273..53403)
                     /locus_tag="VQ664_000052"
     CDS             complement(52273..53403)
                     /locus_tag="VQ664_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HET2788305.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            complement(53487..53876)
                     /locus_tag="VQ664_000053"
     CDS             complement(53487..53876)
                     /locus_tag="VQ664_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HET2788306.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIDITEE"
     gene            complement(53892..54275)
                     /locus_tag="VQ664_000054"
     CDS             complement(53892..54275)
                     /locus_tag="VQ664_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HET2788307.1"
                     /translation="MLEVAYILVALALIVFLVYLIITVQKLGRVIDETEKTIKTLTSD
                     VDVTLHHTNELLAKVNVLADDINVKVATIDPLFSAVADLSLSVSDLNDHARVLSKKAS
                     SAGSKTLKTGASLSALRLASKFFKK"
     gene            complement(54276..55064)
                     /locus_tag="VQ664_000055"
     CDS             complement(54276..55064)
                     /locus_tag="VQ664_000055"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HET2788308.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFGLRVSQWLSVVLIGLGIMIVIYQNRKKAPYYITEEEN"
     gene            complement(55057..55992)
                     /locus_tag="VQ664_000056"
     CDS             complement(55057..55992)
                     /locus_tag="VQ664_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HET2788309.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINTADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLSETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            complement(56122..56298)
                     /locus_tag="VQ664_000057"
     CDS             complement(56122..56298)
                     /locus_tag="VQ664_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HET2788310.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            complement(56438..57145)
                     /locus_tag="VQ664_000058"
     CDS             complement(56438..57145)
                     /locus_tag="VQ664_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HET2788311.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESDLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            57296..58324
                     /gene="queA"
                     /locus_tag="VQ664_000059"
     CDS             57296..58324
                     /gene="queA"
                     /locus_tag="VQ664_000059"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HET2788312.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIINMLEPGDALVMNDTRVLPARLYGQKVETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKENGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHAIQEHYRFFS
                     FGDSMFIY"
     gene            complement(58995..59384)
                     /locus_tag="VQ664_000060"
     CDS             complement(58995..59384)
                     /locus_tag="VQ664_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HET2788313.1"
                     /translation="MVKRRIRRGTREPEKVVVPEQSSIPSYPVSVTSNQGTDVAVEPA
                     KAVAPTTDWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGSMKVNQWFQVGGKWY
                     YVNASGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(59438..60145)
                     /locus_tag="VQ664_000061"
     CDS             complement(59438..60145)
                     /locus_tag="VQ664_000061"
                     /inference="COORDINATES: protein motif:HMM:NF019142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HET2788314.1"
                     /translation="MFRRNLNTSFVHAADGIQYVRDDTRDKEEGIEYDDADNGGIIVK
                     VATKPKVVTKKISSTRIRYEKDETKDRSENPVTIDGEDGYVTTTRTYDVNPETGHVTE
                     QVTVDRKQATDTVIKVPAKSKVEEVLVPCATKYEADNDLSAGQEQEITLGKNGKTVTT
                     ITYDVDGKSGQVTESTLSQKEDSQTRVVKKGTKPQVLVQEIPIETEYLDDPTLDKSQE
                     VEEVGEIGKLLLLQSIL"
     gene            complement(60845..61396)
                     /locus_tag="VQ664_000062"
     CDS             complement(60845..61396)
                     /locus_tag="VQ664_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2788315.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSAENLTYVTWD
                     PHPDIEITRNSIRNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGNGMMTETLKAILDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
     gene            complement(61794..62618)
                     /gene="nadE"
                     /locus_tag="VQ664_000063"
     CDS             complement(61794..62618)
                     /gene="nadE"
                     /locus_tag="VQ664_000063"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HET2788316.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAMEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            complement(62615..64075)
                     /locus_tag="VQ664_000064"
     CDS             complement(62615..64075)
                     /locus_tag="VQ664_000064"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HET2788317.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIHNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDSDIAYLESLGYHGAFLDYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DETGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISDMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            complement(64191..64679)
                     /locus_tag="VQ664_000065"
     CDS             complement(64191..64679)
                     /locus_tag="VQ664_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2788318.1"
                     /translation="MKNRFYYYQLLDEREEQLINKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYVIYLPWVFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            complement(64669..64878)
                     /locus_tag="VQ664_000066"
     CDS             complement(64669..64878)
                     /locus_tag="VQ664_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2788319.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
     gene            complement(65268..65710)
                     /locus_tag="VQ664_000067"
                     /pseudo
     CDS             complement(65268..65710)
                     /locus_tag="VQ664_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000640911.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(66002..66808)
                     /locus_tag="VQ664_000068"
     CDS             complement(66002..66808)
                     /locus_tag="VQ664_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2788320.1"
                     /translation="MILKDINFALNKGEIVGLVGRNGVGKSTLMKILVQNNQPTSGNI
                     ISSDNVGYLIEEPKLFLSKTGLENLKYLSNLYGVDYNQERFRSLIQELDLTQSINKKV
                     KTYSLGTKQKLALLLTLVTEPDILILDEPTNGLDIESSQIVLAVLKKLALNENVGILI
                     SSHKLEDIEEICERVLFLENGLLTFQKVGKDSHNFLFEIAFSSATDRDIFITKQEFGD
                     IVQEEGLRITMSGNIQSSELFKFFNENSIKVVDFETKKETLKDIYLNRSK"
     gene            complement(67214..67942)
                     /locus_tag="VQ664_000069"
                     /pseudo
     CDS             complement(67214..67942)
                     /locus_tag="VQ664_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
     gene            complement(68178..68489)
                     /locus_tag="VQ664_000070"
     CDS             complement(68178..68489)
                     /locus_tag="VQ664_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2788321.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYVCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCPFCFSRFNPGCQNHKERYF
                     K"
     gene            complement(68504..69790)
                     /locus_tag="VQ664_000071"
     CDS             complement(68504..69790)
                     /locus_tag="VQ664_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HET2788322.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFAAKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMKELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDMPFGKERKSL
                     KGEILEEFSMSAVDMSMIDHIPDMIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     LESSEKFEAIKQNLVDEMWKVAQRELATGFYYGTPSENEQLFGARRKIPEYKFVAEVV
                     SYDDATQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDLHDAKGNKIDRAPNPMELL
                     TIKVPQPVQAGDMVRALKEGLINLYKEDGTSVTVRA"
     gene            70414..70596
                     /locus_tag="VQ664_000072"
     CDS             70414..70596
                     /locus_tag="VQ664_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001262531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HET2788323.1"
                     /translation="MANDNKSHYLIYRVLGISFEEGENIDLYQNKGRFLYKYAGSFLE
                     EAAVLSFNEKFGTENT"
     gene            70606..70971
                     /locus_tag="VQ664_000073"
     CDS             70606..70971
                     /locus_tag="VQ664_000073"
                     /inference="COORDINATES: protein motif:HMM:NF021048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HET2788324.1"
                     /translation="MPNSENTKPKTFEIDCLVGEKHAYEIKWWDATTDGDHITKEHTR
                     IKVIHNKGYIPIRLMFYYPNRTQAIKIQQTLETLYNGIGGKYYYGDSAWEHLRAVTGI
                     DLLSILTDIANKKTGVKSK"
     gene            70968..72158
                     /locus_tag="VQ664_000074"
     CDS             70968..72158
                     /locus_tag="VQ664_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HET2788325.1"
                     /translation="MTVLKGDNLEILKTIESSSIDLIYMDPPFFTQKTQKLSNNKNIM
                     YSFEDTWTSIEDYKEFLSVRLEECKRVLKNSGSIFVHCDKIANHHIRLILDNIFGADM
                     FQSEIIWNYKRWSNSKKGLLNNHQNIYFYSKSKDFKFNTIFTEYSSTTNIDQILVERK
                     RNGNSKTIYKVDNNGNYILAKEKNGVPLSDVWNIPFLNPKAKERVGYPTQKPILLLEQ
                     IIKIATDKNDIVLDPFCGSGTTLVASKILNRNYMGIDLSEEAINITQQRLENVIKTSS
                     NLLNKGIEAYRTKTEEEENILKLLQAKIVQRNKGIDGFLPKHFQKKPIPIKIQKNNEC
                     LNESISLLQNAINSKKLDFGVVIKTHSDNLLFDFDTIPENIIVVDHFELTIEKWLSKS
                     QQLL"
     gene            complement(72673..73665)
                     /locus_tag="VQ664_000075"
     CDS             complement(72673..73665)
                     /locus_tag="VQ664_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2788326.1"
                     /translation="MSYYDFVKDYMKVDECKNNEKYSSAGHTFCWKKENSTYAEGLYW
                     FYEGGSFIIDIHDFYIKEEVVQNSTYSMSDYVSIYSSYIVSANGEKFNPYQTITANSL
                     CTFDFDNIKDDFVFLLHENCCYLAVSIGFKKELIEKHLASININPESFYSTLLQPNQI
                     ILTKALERVAMEILNCKMDAPAADFFFKAKANEWISIVIDTYLNRKKYKIEIDDDKAL
                     EDVARFLDDHFATNVNQGTLEKISKMSGTKLKNLFKEKYCQSITEYTQRKRMNVAETL
                     LLNTELPIKEIAESVGYSSASKFSIYYKRYKGKLPSEVRNLACKHHNFKCDYCD"
     gene            73825..75579
                     /locus_tag="VQ664_000076"
     CDS             73825..75579
                     /locus_tag="VQ664_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2788327.1"
                     /translation="MKIYKKLFAYVQDKKYLGVLAIIFSAISAVLTVYGYYLIYKFLD
                     KLIINSNLSGAESIALKSVITLTSGAIFYFVSGMFSHILGFRLETNLRKRGIDGLEKA
                     SFRFFDLNPSGQIRKIIDDNAAQTHQVVAHMIPDSSQAIVTPILVLVLGFIVSIRVGI
                     ILLALTIIGGLILGAMMGEQEFMKIYQESLSKLSAETVEYVRGMQVVKIFKANVESFK
                     SFYKAIKDYSKYAYDYSLSCKRPYVLYQWLFFGLIAILIIPIVYFMTSLASAEVILLE
                     LIMILFLSGVLFVSFMRMMWYSMYISQGNYAVDTLEALYEDMQKDKLVHGNVNNFKNY
                     NIEFENVSFAYNDKAIIENLSFNLEEGKSYALVGSSGSGKSTVAKLISGFYNVNKGSI
                     KIGGIAISEYSDEALIKAISFVFQDSKLFKKSIYDNVALANKDATKDDVMRALKLAGC
                     DLILDKFPERENTIIGSKGVYLSGGEKQRIAIARAILKDSKIIIMDEASASIDPDNEF
                     ELQKAFKNLMKDKTVIMIAHRLSTIKDLDEIIVMDSGKIIERGSDKELMSKDTRYKSL
                     QEMFNSANEWRVSNERVL"
     gene            75563..77284
                     /locus_tag="VQ664_000077"
     CDS             75563..77284
                     /locus_tag="VQ664_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019214631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2788328.1"
                     /translation="MKEFYKKRFALTDGGARNLSKATLASFFVYCINMLPAILLMIFA
                     QEVLENMGKSNGFYIVFSVLTLIAMYILLSIEYDKLYNTTYQESADLRIRTAENLSKL
                     PLSYFSKHDISDISQTIMADIEGIEHAMSHSIPKVGGMVLFFPLISVMMLAGNVKMGL
                     AVIIPSILSFIFIPLSKKYQVNGQNRYYDVLRKNSESFQENIEMQMEIKAYNLSKDIK
                     DDLYKKMEDSERIHLKAEVTTILTLSISSIFSFISLAVVIFVGVNLIINKEINSLYLI
                     GYLLAAMKIKDSLDASKEGLMEIFYLSPKIERLKEIQNQDLQEGDDYSLKKFDIDLKD
                     VEFAYNKDAKVLNGVSFKAKQGEVTALVGASGCGKTTILKLISRLYDYDKGQILIDGK
                     DIKEISTESLFDKVSIVFQDVVLFNQSVMENIRIGKQDASDEEVKRAAKLANCTDFIE
                     KMDKGFDTVIGENGAELSGGERQRLSIARAFLKDAPILILDEITASLDVNNEKKIQES
                     LNNLVKDKTVVIISHRMKSIENADKIVVLQNGRVESEGKHEELLQKSKIYKNLIEKTK
                     MAEEFIY"
     gene            77295..77924
                     /locus_tag="VQ664_000078"
     CDS             77295..77924
                     /locus_tag="VQ664_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HET2788329.1"
                     /translation="MDNKKLKVKDLVSIGVFGVIYFAFMFGVGMMGLIPILFLIYPTV
                     LAIVAGTVVMLFMAKVQKPWALFIFGMISPLVMFAAGHTYVVVVLSLIVMIIAELIRK
                     IGNYNSFKYNMLSYAIFSTWICSSLMQMLLAKEKYMEWSLMTMGKDYVDVLEKLITYP
                     HMALIALGAFLGGILGAYIGKALLKKHFSNGLYCVGYFTPCLILWCYLN"
     gene            77825..78382
                     /locus_tag="VQ664_000079"
     CDS             77825..78382
                     /locus_tag="VQ664_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001851583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HET2788330.1"
                     /translation="MYRQGSIEKTLFKWIILCGILYSLPNFMVLSELNPIVKMFLSIP
                     IVIRMFILPFMAASFMIKTSDVGAIISSMDKLKISKNVSIPIAVMFRFFPSFKEEKKN
                     IKMAMRVRGINFKNPVKYLEYVSVPLLIISSNISDDIAKAAETKAIENPIAKTRYIRV
                     KIQLIDFVYVLAVAGLIVGGLIWLK"
     gene            78370..79734
                     /locus_tag="VQ664_000080"
     CDS             78370..79734
                     /locus_tag="VQ664_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2788331.1"
                     /translation="MVEIKNLSLDYGEEHILDDISLSIAEGECVLFTGKSGSGKSSLI
                     NSINGLAVRYDNAKTKGEIIIDGKNIKNLELYQISMLVSTVFQNPKTYFFNVNTTLEL
                     LFYLENIGLAREEMDRRLKDILEIFPIKNLLNRNIFNLSGGEKQILCIAASYIAGTKI
                     IVMDESSSNLDIKSISVLAKMLKILKEKGISIIVAEHRIYYLMDIVDRVFLIDKGKLK
                     KTYTRSEFLKLDKNELNALSLRDKELSKLKVPYLKEGGEYQIKNLSYKFTDDECLSLK
                     DISFKLGKIYGIIGSNGRGKSTLLRCLIGLEKKSKEEIYFKGEKLSKKERLKNSSLVM
                     QDVNHQLFTDEVFNELRLGVKNFDEEKAKIILKDLGLDEFIERHPMSLSGGQKQRLAI
                     ASVMCKTSPFIFFDEPSSGIDYSNMIKISELINKYKTMDKIIFIVSHDIEFLNEVADE
                     IFEL"
BASE COUNT        24632 a        17071 c        14696 g        23717 t
ORIGIN      
        1 acctacggct agcttcctag tttgctcttt gattttcatt gagtattaca gtaaacaatt
       61 tttctagcta ttgtaacaaa aaagtcactc gaaggcaact tttttcgtcc ataaactttc
      121 aaaagagaat ggcttattca gaactaaaag ccgcagcttt ttgcatttgg taatacttac
      181 cctttctatc catgagttct tgatggttac catattcaac aatatcacca tctactaaga
      241 caagaattaa atccgcatcc tgaatggttg acaaacggtg agcaatgatg aagcttgtgc
      301 ggcccttcat gagttttgca aaggcatcct gtaccagcac ttctgtccgt gtatcaatgg
      361 aagaagttgc ctcgtctaag ataagaatct ttggaatagc cagaaagact cgggatatgg
      421 tcaagagctg agcttggccg acagagagag attctccagc attttccaac ttggtatcgt
      481 atccctgtgg caactgttgg atgaaaaagt ctgcattagc tgctttggca gcagcaatta
      541 cttgctctcg actggcttca ggattgccaa aggcaatatt atcatgaatg gtcccttgtg
      601 tgagccaggt ttcttgaagc accataccaa actgctgtct caatgatact cgtgtataat
      661 cataaatgga ttgcccatcc agcaagatat ctcccgagct aatgggataa aaacgcataa
      721 ggagattgat aagagttgat tttccagcac ctgtcggacc aacgatggct accttactac
      781 cagctggaat atcgatagac aactccttaa tcaaaatttt ttcaggatgg tagccaaaag
      841 agacatgttt aaaggaaata gctcccttaa cttggtcact ggtcaagact tccttacctg
      901 tttcagccac ttcagggcta tctaagaccc catagatacg ctctacgcaa gccagagcac
      961 tttgcaactc agctagcact gaagaaatat cgttaaaggg cttggtgtat tgctgaacat
     1021 agttcaaaaa agtcactaaa cgaccgacgg tcaaggttga acccatcatg atacgataag
     1081 ctcctactcc agctaaaagg gcataaatga gtgcatttac aaagcgagtc gaaggattga
     1141 ccgttgaaga ataaaagatg gctgactgag aatagcctga gtagttgtca tgagcctcac
     1201 gcaatctttg gataaattct gtttgagcat tgaaggactg gattatagtc tgctggctaa
     1261 gcgattcttc aatcaactga gtctgaattc ccctcgtctc tgtttgcttc tggaagagat
     1321 gataggatct cttggcaata aagcgtgaaa tcaccatgga cagtggcgtc aacagcaaga
     1381 ctaagagagt catgaggaga tgaatttgga gcatggctag aatactaacc aaaatcatca
     1441 aaacaccaat gaaaaattgg ttaaaaatca tggtcaagcc agctgccaac tgttcgatat
     1501 ccgtggttac acgactgacc atctctccat tgccttgccg atccgcaaaa gcaatcggta
     1561 accgatggag tttatggatg attcgctctc gtaaatctct ggtataagag aagattagac
     1621 gattatagag gagaggattg gcccattgta ccagagtatt tcctattacc accaagagca
     1681 tctggagaaa aatctgccaa aaaactggtg atgaaccagc cactaggact tggtcaatga
     1741 cctgcccaat cagaataggt aggtaaattg ataagccaac ttgggcaata gttcctagaa
     1801 aggctaggaa aaggaggaag ggatggtttg ctaaatctac gactaaacgt ttgagcgtct
     1861 ggtttacagt ttgtcgtttc attctagtcc tcctttccat gttgggatgc attgatttca
     1921 cgatagactt gactggattt catcaagtca tcgtgcttgc caacagctag caactcacct
     1981 ttttccaaga ggagaatctg gtccgccatc tggagtgtcg aagtccgttg agaaatcaag
     2041 attaagctca tatttggcag attttcgcgg atagctttca agagcttgga ctctgtaatg
     2101 gtgtccagtg ctgaggtcgc atcatctagg atgagaaacg gagcctggcg caagactgct
     2161 cgtgcgatag acagcctttg tttttgtcca cctgagaaat ttcgccctcc tgcttcaact
     2221 agagcatcca agagtccttc cttatcactg acaaaatcct tagcttgcgc aatctccaag
     2281 gcttgccaga gttcttgatc agtcacttct tgatttaaac ctaaagtcaa gttggaacga
     2341 atagttccct taaagagttc gaccttttga ggtacatagg caatccaaga ccgccactgc
     2401 tccaaattaa gaggactacg tccattttga taaaggtcaa tgttcccctt gtctactgga
     2461 taaagtccaa gtaagagttg caccaagctt gatttaccag aaccagtccc cccaatgata
     2521 ccaaggattt gtccttgagt catatcaaag gaaatgtctc tcagagaagg ctgggccgca
     2581 tcaggatagg taaaagtcaa ttcttggact tgtaaaaccc gaccactggt aacttgcttt
     2641 tgttctaatt ctgaatggat gttttcggga gattccgcaa agacctcctc gattctcttg
     2701 gctgagatat aggactggtt gagggaattg atcagcatgg ctagcttgac caattccacc
     2761 aaaatctgta agaggtaatt gataagagca atgagagcac cttgactgag tactcctcct
     2821 tgaattgaaa tatagccttg ccagataata acgagaagag ttccattgac aatcagatag
     2881 gtcagaggtg ttaataaact agacaagaaa cctgtctttt cttgtaatct agcataaact
     2941 tggttaaggg tttgaaaaat ctgtaactct cgtttttctt gaccaaaagc acgaataacc
     3001 cgcatccctt gcaattgctg gcgcgtttcc tgaaccagtt ggtccgtttt ctttctgaga
     3061 ctactgtaga gaggattgac caatcgagat aaccctacaa tgacaatggt caaaatggca
     3121 accatgacta agaaccagaa agtcaactca gctgagattc gataagccat aaaaatggca
     3181 ccaaaaacga taatgggcgc tcgtaaaaag agacgcagga attgattgat accagtctga
     3241 atctggtagg tatccgaagt caagcgagta accaaactag aagttgtcag acggtctctg
     3301 ctgtcctttg gcaaggaaag aatatgacga taaagatcgt ttgtcaattc cttagcaaaa
     3361 cctactgctg cctttgctga gtaaaattga gctatcaagg ccactaaaac gccaattact
     3421 gcaaagataa ggagcaggcc aatctgcatc cagagatgac cttgatctcc ctgaggtaaa
     3481 gattggtcaa caatcccagc aatcaccatg ggaaccaaga gctcaaaaac agcttctaac
     3541 agcttgaaca agggggctaa aattgattcc ttgatgtagg gtttgaagta agataatagg
     3601 tgtttcataa atcccttcta ttcatattct agaaatgaag aaagtgggaa gccccactct
     3661 ctgttttatt tgtttaagta aggcaataga tagccatatc ctgctttttc catctcatcc
     3721 ttggccacaa agcgtaaaga agcagaattg atacagtaac ggaggccgcc taactcccgc
     3781 ggtccatctg tgaaaacatg acccaagtga gcactgcctg aacgagaacg aacttcaatt
     3841 cgctccattc catggctcag atccttgtaa taatgaatca actctttgga aatcggacgg
     3901 ctaaaacttg gccaaccaca acctgaagca aacttatcct tggcaaaaaa gagtggctca
     3961 cctgtcgtaa tatctacata aatcccctct tcaaaggttt ggtcataggc attggtaaat
     4021 ggagcctctg tagcagcttc ttgtgtgaca cgataagact cttcagatag actggccttc
     4081 aacacctctt gactaggctt ttcatagttt gctgcatcaa tcaatggctt atcagcatcg
     4141 gtcacatcga tatgacagta acctgaagga ttcttcctga gatagtcttg gtggtagtct
     4201 tcagccagaa tgtagtggcg taattgctcc acttctactg caatctttcg acccagcatg
     4261 cgttcctgct cctgcaccac tgtgtagata gctggcaaat ctgcttcatc ctgataataa
     4321 atcccagttc gatattggcg accacggtca ttcccttgtt gattgataga tagaggatcg
     4381 ataactcgga aataataaag taaaatctct ctgagtgaca cttccttctc atcgtaaatc
     4441 acttggaccg tttctgcatg gtctgtttcc ttgatcaact ggtaattggt cgtttcgact
     4501 tgaccattag cgtagccaac actggtttct agcactccag aaatgcgtga aaaatattcc
     4561 tctaggcccc aaaaacaacc acctgctaga taaatttctg ccatctttat ttctccttta
     4621 tcacgttttt aactaatact cttcgaaaat ctcttcaaac cacgtcagcg tcaccttacc
     4681 gtaggtatgt tactgacttc gtcagttcta tctgcaacct caaaacagtg tcttgagctg
     4741 acttcgtcag ttctatctgc aacctcaaaa cagtgttttg agcagcctgc ggctagcttc
     4801 ctagtttgct ctttgatttt cattgagtat aaacttcttt tcacaaaaag gatatgaaac
     4861 cctctggtca agagtttccc catcctatct tctattcttt attttgcttc tacacggaca
     4921 cctttggtat caactctcaa gtcatgcagt tttcctttga aaggttgctt ttccaattct
     4981 gccttaattg ttggcatctt gtcatgagaa gccagaacca taactgtcgg cccagcacca
     5041 gaaaggtagg ttgcataggc cccattttct ttggtcactt gcttaatcat cgcaaattct
     5101 cttaccaagt cctgacgata gcgctcatgg aagaggtctc cctcgattgc ttgcccagcg
     5161 gtcaccatgt ctcctgccaa caaggcagca accgctacat tggcgataga acttgcagca
     5221 acagcttcct tataagacaa ttttttaggc aagacactac ggctgtcgcg agtacgtaat
     5281 tcatagtttg gaatgtaagc tagaaaatca cactctggaa agtctgctac gatagcagag
     5341 acttgccctt caacagaact tgcaataacg agattaccat aaatggctgg agccacattg
     5401 tcaggatgcc cttcaatctt ggtcgctaac tgcaattttt catggtctga taagttgagt
     5461 tgacccagtt ggttggctag ttcaatccca gcaacgataa ccgagctgga agaacccaaa
     5521 ccgcgcgcca aagggacatc actggtcatt ttcaagcgtc ttggttgcaa gtctggtaca
     5581 atttgcaaag cgattttaag caagagatta cgctcgtcat gtggaatcca tttgccaatc
     5641 tggtgttcaa tcagccactc atctcgttct tcgcagacct caatttgaag atacttggtt
     5701 acagctacac cgaccgagtc aaaacctggc ccgatattgg cactggttgc aggtacaata
     5761 atcttcatct tattctccta gcaccttgaa ggtattcaag aggtcgaatt ctgaaacctt
     5821 cttcaattca gctgagacat tttcaagctg ggctttatta atcttgtgtg tgatgataac
     5881 gacacgcgcc ttgtcaccct ctttgccatc ttgaaggatt tgcttaaagg aaatatcttg
     5941 agcattgaag atttcagcca acttcaagac ctgacctttt gagtctagag ccaagattga
     6001 gaaatagtag tttgctttga catcttcagg atttgccaag accaagtcac ggctatattc
     6061 gttgaagtct ttgccaatag taccatcatt caaacgacga acgatacgga caatatcagc
     6121 tacaacactt gttgcagttg gtttttgacc cgcacctggt ccgtagtaca tagactcacc
     6181 aataccgata gattctacaa agacagcgtt cattacgcca ttcacactag caagtgggtg
     6241 cgctttaggt aggaaggttg gagtcacttc tgcagcaata cctgaagaag tttcctcaat
     6301 agaaccaacc aatttcacta cgtaaccaag ctcttgagct acagctacgt cttctggtgt
     6361 gatattgcgg attcccttgt gggctacatc atcaaaggca atcttcatgc caaaggcaaa
     6421 ttggctcaaa ataaccatct tgtaggctgc atcaatccca tctacgtcat tcgtcggatc
     6481 gctttctgca aatcctagac gttgtgcttc cgcaagagca tcatcgtaag accagccttc
     6541 ttccaccatc ttggtcacca tgaagttgga agttccgttg actactccaa gcacgcgcgt
     6601 aattttatca gaagccaagg aatttgctaa agtacgaaga attggaatcc caccagcaac
     6661 tgctgcttcg tagtaaagtg ctaccttgtt agcttgagcg atttctagca attctgcgcc
     6721 atggacagct aaaaggtcct tgttagcagt aacaacgtgt tttccagctt ccaaggcacg
     6781 agtgataaag gttttagcag gctcaatacg ccccatcaat tccactacga tagtaatatc
     6841 ctggtctgat aaaatatcat ccacattggt tacaaagtta aagtcattcc ctgctgcaag
     6901 caagcgattt ttttcatctt catccttgac caatacctta gcaactttga tatctgaatg
     6961 tgctgattga ttgatttttc ctccattttc ctttaggagg aaaggcacac cacttgcaac
     7021 ggtaccaaat cctagtaaag caattttaac tgtcatcttt atctcctcga aattttctaa
     7081 tatagccatt ataacagaat tttgtgaaaa ttcctattat agtaaatcac tatttcagta
     7141 taaaaagaaa aaacgaatca gacgattcgc tcttcttaaa atctgaaaat agctttccag
     7201 aaaagattag ccgatttttt gcagattgag cactgcatcg tgactcatca agacttgacc
     7261 atactcttgt aagactgagc gactgatatc actatcgtct gcaaactcgc gcatacgggc
     7321 caacagccaa gctggatatg ggcttggatg attttcaata tccactaaaa tggtcaaata
     7381 atagcgctcg ttcattttgt agagttcaga agtttccatt tcaaaagtca ctgtcttggc
     7441 aaaagctacc aagtcagcca acttagcaaa agaaaggatg tagtagatgt aaggttcttt
     7501 cttactctca gcttcttgtt cagcctgctc ttgctcttct tccttggctt caacttgctc
     7561 aagagattga atggcttcga tatcatcctt ggttttgtct gcgatgcttt tttccagggt
     7621 tttgataaat tcatctggag acatttgagc caattcttcc atatctggca aatccgataa
     7681 gtcttcaaaa tctagatttt ggtcaatctt tgacttggtc acaaagacat ctaccttatc
     7741 aggttttgga gtcacacgga agctcaacat gcctgtatcc agaaagctat caggcatctc
     7801 tagctcatcc aagatagcat aaaagaactc ttctgttttt tcttgaggaa cgagaaagtc
     7861 agcaatctcc attccacgat ccatcaaatc ctctaaagac atcgtgattt ttaaagttgt
     7921 atcactaatt tgtttcattt tcattgctag taacctcata ctttcagttc tatctattat
     7981 actagatttt tacgatttta tcaaaagaag gctcctctat acggatagat tttccctagg
     8041 gtctttctat aggagactcc aagagaaaat ttctgcagac agatagaaaa agccttcaaa
     8101 atcggctaag agccgatttt gaagacctta tacatcagaa tacttataat ttaaaggttg
     8161 ctacaccgag gatagaacga tttaagtttc tgagaatttg aagactttgc tcaaatttct
     8221 tataacgagt cactccgtac tcttcaacaa gaaggactgt atctctttcc aaaagagatg
     8281 atacatcctg taaatctaca aaatgcattc cttttaaagc ttcttgactc tgtttcaatt
     8341 tatctaggat agctttattt gagctaacga tggtcaattc ctgtccagta tttttgtatg
     8401 acaaaacatc tgctaggtta gcaattgttg taatctctgt tacaaaatca atttgatact
     8461 gagaaaaatc acctactcta ttgattgttg gattaaagag ataaactaac acatttccca
     8521 tcacaaccaa aatcacacaa accactccaa taacaactaa acgaagaatc agatttttca
     8581 catttaagcc aagcgctgtt tcaccatttg cgttcaattc tttagagttg atggtttcca
     8641 gtttttcaat tttcacattt gcataggcat gtttaaattt ctcaatcaac ccatcaattt
     8701 ttttctctaa caagtcattg gcatctttac ttgatgtcaa aattttcaca ccaacccctg
     8761 catcgtcaat catatagtag acggtcaatt ttttccacca atagtcattc gttgaatttt
     8821 tcaaggttgt ttctgtcgtg tctaattcac tggcaatttt tttcaactca ctgggttcta
     8881 catcattgaa aagataagct ccattcaaat taccatcaat caatttccca taaaaatcac
     8941 tataaccacc aatttgatga ttcaaaatcg ttttggccga ctcttttgga ggagtgattt
     9001 tatagataag ataagttgaa taacttgttg tatctttgac agtgttttta ttcctaactg
     9061 ctttaattgt aaatggtaca gcaatgagag caaataaagc gatgagagct aaaatatttg
     9121 cttttcgctt tttataaaga tttgcaaaca aatcagctac tgaataatgt tcaaacatga
     9181 tttttttctc ctttgtttag tagatactag ttttcctttg taagcatttt tgctataaat
     9241 ataatcacaa gaacaattcc ccagaattgc attgtaaata aattgaagaa actttctgaa
     9301 aagctgcttc ttggcataaa gaatagatta ttcaagatga gtagggataa agcaaatagg
     9361 attgtccttg agcgataggc tacttgcagc atggctataa ataatacgcc gagtaagaaa
     9421 ctaagcagaa agactccaat cataccatag tcggtataca actccatgat ataactactt
     9481 ccgataccat gccctttcag gtattccttg ttcaagacaa gataggatag attgtgggca
     9541 taactattac tatcaatagc tagttccaca ctattggttg tatgttcaaa ggcttttcct
     9601 ccgaaaatgg ctcccaaact cccccttgca aaataatcaa gaacaggacc aaaagtaaaa
     9661 ttacggaaat ctcggtaagg gaggctactg ttaaatagaa aacctcgagc cagaacacca
     9721 aaactagtcc cttgtttata gataaagtca agtaagatat cccagaaacc tgtatgggaa
     9781 acttggacat tatcccgtac ataattgagt actcccatcg ctaacatgag aataggagaa
     9841 cctacaaaaa tcgctaactt ttctttaaac ccaatccatt ttcctttttc agtttgctcc
     9901 cgcataaagt aataaacaaa agcaaataaa atacttaaaa taaagggatt tcgtgtccca
     9961 attgccaaat gaatagtatt agctgcaata aaggagacaa gcactgctgt ggcctgcaat
    10021 ttctttggct tggttgccag atacatacac attgcataga ccgtaaaggt agacaaaatg
    10081 taggtaaaat aaggcagttt actttcaaaa tttgcatagt aggcatagta ggaagtctgc
    10141 aaacgataca agagccgttc aaataaccga atgaaataga aaggataagt tagaagaaaa
    10201 actcctagtg atacaaagcg taaccgcttg atataaacct cttttagaga atttcctata
    10261 tttgctactt ttattttctt cctagctatg aagtaacgag ccagaatgcc tcctgtggtc
    10321 aagcccagaa tcgaaaccat gacaactata aaggcaaaac gataggctat tggatgatag
    10381 gtatccaaag caccatccct aaaataatca atggtcggtc ttgataccag aaatacaaaa
    10441 atggttaaat agaaaataaa atggattaag taatacttga tatcattcca acaagcaatt
    10501 aagctactaa ccaacaagaa caataaagta gaaagtaagc taacattatt attattaaac
    10561 agatacacaa ttccacttac tagcgtcaag gcataactga ctatggtcaa actaaataat
    10621 aatcgtttcc catcaatcac ttggtcaccc ccgttctaat gtaatttttt agatttttca
    10681 atatttttca gtaataagaa tcgatataag gaaatattta tgaatagggc caaagcacta
    10741 attcttctcc ccttacggaa aattggattc ctagaaatag caaaggcatg gccttttaaa
    10801 aaacgatgaa tctgagaata ggcttcaaac tgtttatact gatcatctag caacatctta
    10861 tccagaataa agaagtgggc ataggccaat ctgaaaaaag cgacctcttt caagtcagga
    10921 tagtttttca caacttcatt ataaaacttt tggtagatat caatataggc taaatccttc
    10981 tctgcatagg gtttggtcgt aatactatcc cctctatgga aatagtaata atagggttta
    11041 gtattaacca catacttctt ggccaacttg attaaatcaa aatggtaata ggcatcttcg
    11101 taaatcaacc ccttaggaaa ggatagggca gttgcaatct gtctcttgat tagcttattg
    11161 caaatcgtcc caggtatttt ttcacctatg aggtattcct ttagaaatgt ttgagaatca
    11221 cagacaaaat agtcatcctg attggctgac tgtgggcttt catcattagc atagacattc
    11281 atgacaccac agcttgaaac atccgcatct tcttgaacta attgctcata taagctctga
    11341 atcatttctg gatggatata atcatctgag tcaataaaaa tcagataatc cccgtgagcc
    11401 tgcttcatcc catcatttcg tgcttgcgac aatccttcgt tctttttatg aagcactgac
    11461 accctgtcat cttgttcagc gattgagtca cacaagcgac cactttcatc tgttgcacca
    11521 tcatcaacaa gaataatttc cagattttga tagatctgct tctgaatgga agctatcgat
    11581 ttttctaggt actgcgccac attatagact ggcacaatca cactaattaa tgcagtttcc
    11641 atgctactcc tctaatagtt tttctacttg ttcgatttgt tttgtaattg taaattgttg
    11701 aatgaattgg ctagcctcat cgacatcaaa gtttgaggca gaagtcatgt aattagtaat
    11761 cgcctgagct gcctcttgat tgctctcaat gatttgtcca aatcgtcctt cttgggataa
    11821 ttcctcagcc cctccaacgt ccgtagagat aaaagggagt cccagactca aggcctccac
    11881 atacactcca ggaaaacctt cttgtttaga catagacaag agaactttcg tctgagataa
    11941 atactgataa ggattttttt gataaccaag gaaatgtaca tagtcctcaa tcccatactc
    12001 tttgactcgt tttttcagtt cctcttccat atcaccagcc ccgataaaat agagatgata
    12061 gttttttccc tcttggtgta ataatcgtat cacttccact acacggtcag aacccttatt
    12121 ttcctcaatc cgtccgatag tacagatact ttgaggagca atctcgatat cgatcttctc
    12181 ttgagatttt tctagaatag tctgaaaatc atatccattg tagattatct gtaatttaga
    12241 agcataatct ggataaactt ccttgataga attgctggtc ttttttgaaa tccctacaat
    12301 tgtattcgca gcatccaact ggcttctatg tgattctctt ttagagctat ccttaagaag
    12361 ttcttcaata cttccatgaa tccaagatat cttcttgact tctcttcttt tagagaacaa
    12421 cagtggtgga ttcataatgg taaaagaaac ttcaacatca taatcatctt ttacaagcaa
    12481 acgacgagtc agtcttggaa aataaattct cattctccac aaaaaagctc gtaaccatct
    12541 ggtttggcga taatcttgaa gggattttaa aatgcgtaca tgctttggaa cagattcata
    12601 tcccttgtca aagtgctcca tttcaagaat atcaatatca tacttttcta gatccagatt
    12661 tgaaacaatg gttgatagaa tcttctctgc accacctcca agagaaaaag accacataaa
    12721 aaataagatt tttttcttag ccaccatatt ctcccttgta ttctgtataa gacttatcca
    12781 tatcagcgat gacagcatca tgatgcggta cctgcttgtc tgctggtgga ggcgtcatat
    12841 aatccccaaa agcagttctg agatagacat catagccgat tggaataggc atctctgttc
    12901 cttcaaatgg caagaaaaga ttgtcttcaa aagatgtgat tgggtacttg tttctcatgt
    12961 agccaggacc tgagcataat tctgtaatgc catcacaatc agccaaatca tacttagtca
    13021 tttctttctc agcttttttc cagatgcgat aacggagaga ttttggagtc aaacccagta
    13081 aaatgcgact tccccatttc atgagagcac catgcttttc tggaatagtt tgcgcacaaa
    13141 agagtgaata aatcaaggcc caacgaacct gttttttccg ctcagctgga tttttcggat
    13201 aataatccaa aggcaaaaca tccaaggtca gaccatgtgg caaatctaaa tcctgctgat
    13261 aaggcttgat acaggtggtt tccttgtcac gaatggtaat aaaaagatta cgatcaacaa
    13321 aatccttgtg actctttgac aagaaataac gttcatctgc ataacgaggc cataattctg
    13381 ctaatttctc ataatcttta cgaggcataa aaaagtctag gtcgtcgtcc caaggaataa
    13441 atcccttgtt tcgaagggca ccaatagcgc ctccgccaca gagataacag agcaaatcat
    13501 gttctttaca aaaggccaca aaatattcag ccatctccag actacgagcc tgaattgctt
    13561 ttaaatcagt catattgttc attattcttt ctatcgtatc gtttcattat accacaaaca
    13621 aggggtgaaa atctattgca gactgtaaaa aatcaaagcc tgactgctat ccaaatagct
    13681 atcaaacttt gatttttctg tcttatactc ttcgaaaatc tcttcaaacc acgtcagctt
    13741 caccttgccg taggtatagg taactgactt cgtcagtctt atctacaacc tcaaaactgt
    13801 gtttttagca gcctgcggct agcttcctag tttgcacttt aattttcatt gagtattatc
    13861 ttatctcaag cccatttgag cgagcttggt ttgatatttg ttttgatcaa ccagcaagcc
    13921 caagcctcca taaacatcat aggcatctac ccagtcaccc agttctggaa tcgtcaattt
    13981 ttcaatacca ttttttgctc catccaaaac agataaaccg tttgttagga ggaaagtata
    14041 gggtacgttg gttgaggtca tagcaaaaac ctttccaaga gcttcagaac cagtgaaaag
    14101 tttagtggga tctttaattt gctctaaaat tgctgttaaa acttgttgct gtctttttgt
    14161 acggccgtaa tccgcctcat catcatcacg gaaacgagca taattgagca gggtcgagcc
    14221 attcatctgc tgttttccga ctttaatggt ttgggttgga gactcagtct cggtagcgta
    14281 taaatcatct ccgactgtag cttctgttag gggacgccca ttcaatgttg aaaattgagc
    14341 atcaatcgtc accccatcag ggaaaagcgt gtcaatcgct gtggcaaagg cctggaaatc
    14401 aaccaaggcg tagtacttaa tgtccaagtc aaaattatct ttcaagactt ggcgaaccat
    14461 ttctgcccct ttttgcccct cttgttctcc taactcgtag gctacgttta acttgttatc
    14521 tgtctgtttt ctaccattaa tcacttgact ataaccatct atatagacca aattatcacg
    14581 catgaaactg actagcttca ttttcttatc tgagcccccg acatttaata ccataataga
    14641 gtcagttcgt gtctcaacac tgttctggcc gattcgacca tcagtaccca tgattaaaat
    14701 attaactcca tctctagtgt cctgaccatt aaagacttct acttgagctg cccgggcatc
    14761 agcagttttc tttgcgctag catcttggta accacgcaaa aacatgaata ccatggccaa
    14821 agccacacag accaaaagtg aaaaaatcac cataaaaatt cgtttaagac ggagcttccg
    14881 tcttttcttt tttggaggga aagagagtgc ttgtgatttg gattgtgagc gactccggtt
    14941 cgcatagctt ggtaagtcaa cctgctcttc tctttcttgt tccaagctag agctactatt
    15001 tcccctagca agagttagct tttcttgcaa ataggcaaac tcattttttt ctctctcatt
    15061 gagatagtga atatttttta gcaaataatc ataacgcaac tgctcatgat gacttaaggg
    15121 attttcttta ctcatcttct ctcctttcca tggtctgata ttggataaat aggataggca
    15181 cccagaattt tatactggat tccaatcgct tctaattctt tttgggcaaa gtggaccaag
    15241 tccttatcga tataatccac atcgataatg aaaaagtatt cacccagtgc tgtcttgagt
    15301 ggacgacttt caatttttgt caagtcaatt cctcgccaag caaaggtcga cagggcctta
    15361 taaagtgcac ctggaaggtt gtcaggtaat gtcaaggcca aactcatctt ttcagtttgt
    15421 gcttgcaagg gaatactagg cttttcagct cctagaaccc agaaacgtgt gaaattggct
    15481 tccatttcct gaatatcctc ggcaatcagt tccaatccat attcttcagc agaacttcta
    15541 ggtgcaactg ctgcaaaggg ctggtctgga tgttcggaaa taaaacgggc cgcataagct
    15601 gtactagctg ttacctcgat ttgagcctct ggatattgtt catcgatgaa tttctttcct
    15661 tgagccaagg cctgtggatg tgaaaaaatc ttttcaatct tagtatggcc tggaaccacc
    15721 atcaactgct gatgaatagg ctgaacgatt tctgctactg cttggatgtg agcctgatga
    15781 aaaagatagt ccaaggtttc atgaacacta ccctcaatag aattttcaac tggcaccaca
    15841 gaatagtcca ctaatccttg ctcataagcc ttgatgacat ctgtaatgtt ggcaaaagcc
    15901 tgcaattcct catgaggaaa agctgtctgc acaacgtggt gtgaaaatga tcccttggga
    15961 cctagataag ctattttcat cttagttcct ctataatttc ctctgggctt agcttggtca
    16021 catccaaaac ccgactagcc acttcctcat accaagcctg tctttcttga aaaatagcta
    16081 ctagttcttc cttgctatta tttagaaaaa gcggtcgctg attgtcctta tcagctgcga
    16141 tacgtaggta gagggtttca aaatctgctt tcaggtagat gttatctgta ttagtcttga
    16201 gtaagtcacg atttctctga gaaataacca ctcctcctcc agttgacacg acttggtctg
    16261 tttgtagtaa atcagctagg acttctgatt ctacatgacg aaaggctgct tctccctttt
    16321 cagcgaaaaa attcgcaatg gacataccta ggcgcttctc aatcagagca tccatatcaa
    16381 ggtaattagg gtccaagcct cttgcaatag tcgattttcc agcccccata aaccctaata
    16441 acaccttagc catgaatcaa gctctccaaa tcatcaaaga aactaggata gctggtattg
    16501 atggcttctg cacggtcaag ctccacctct ccatctgcaa ccaagagggc tgcgatagct
    16561 gtcatcatgc cgatacggtg gtcaccaaac gtattgactc tagcaccgtg aagagctgat
    16621 ttccctttga taatcatccc atctgccgta ggagtaatat ctgctcccat actatttaag
    16681 gcgtctgcca caacctgaat acggtctgtt tccttgacct tgagctcctc agcatccttg
    16741 ataactgtta caccttgggc ttgagtcgca agcagggcaa taatgggcaa ttcatcaatc
    16801 aatcgtggaa tcaaagcgcc accaatctct gttcctttca agtcagaaga ctcaacaatc
    16861 aaggtagcag atttagcgac tggatcgatt tcagttattt ccaattttcc acccatggca
    16921 cgaatgacat caataatacc ggtgcgagtt tcgttgatcc ccacattctg cagcactaga
    16981 cgagaatttg gagcaatcaa acctgcgact aaccaaaagg ctgcactgga aatatctcct
    17041 ggtacgacca ccttctgtcc tgtcaatttt tgtggcccct ggactgtgat tttcttacca
    17101 tccacactta aatgaccacc aaattgttgc aacatatctt cagtatgatt acgggtgtac
    17161 tctttttcga taataactga ctccccctta gcttgtaagg ctgcaaacat caaggctgac
    17221 ttgacttggg cagaggcaat tggcaactca taatgaatag gtcttaggtt tttcgtccct
    17281 tttaagcgaa ggggaggcaa gtctcgttca gtttgccctg aaatgctgac gcccattttt
    17341 ttcagtggaa gggtcacacg gtccatagga cgtttggaaa gactatcatc tccaaacatc
    17401 tctacttcga aatctgcacc agcaaggaca cctgaaatca ggcgaatcga ggtgccagaa
    17461 tttcccatat taagggcatt ttgtggcgct tttaagccag ccatgcctac accttgaatg
    17521 gtaataaccc catctttatc ctcaatttca acaccaaggt cacgaaaaac ctgcatggtc
    17581 gaaagaacgt cttcacctcg cagaatatca taaaccttgg tctcaccctc agccaaactt
    17641 ccaaagataa tggaacggtg gctgatagac ttgtcacctg ggacgcggat actaccatgt
    17701 aaatggcgaa tgtttgtttt tagtttcata ctggacctca tacttgcaat acttttacct
    17761 attttatcat aaaaagtcag aaattcctta aaaattcctg actttaggat cgttcttttc
    17821 ttatttcagc aattctgaaa ctggttcaaa aacaattttt tcaatgtcag aaaggtaaat
    17881 ggccaattgt tgttgcttgg taaagaattc tgacaagagg ctatttcctt gaatctgttt
    17941 accaaagcct tccatcttag cttggaagga cgcatctggc atttgacctg tctgtgctag
    18001 tttttgaatt tcctcttgaa aggcaagata ttctgtaaag attttgcttg cctcagcatc
    18061 tgctgcaatc gcatctttag ctgctttaac agccttgtat tctggtaatc cgcgtagacc
    18121 gcgactgagt tcgtttgcac tatcgtaaat atttgacatg ttcttctcct tatttgatga
    18181 cgactgtata gtcggtattt tctgttatga gatgctcagc tctttccaag tcttgagcat
    18241 ttttaaatga aatttgtagg attccgtgaa tatcctcacg attttcctcg ttgatgtgga
    18301 tgttaaccaa ggaagttcca cgtagcagtt ccaaaatccg caggatgaca tcttcttcat
    18361 caggaacgtc aacatagagg tcgtaagagc tatccacacc accacgctta tggatttcca
    18421 tggtctggcg ttgttcacgc gcttggttaa aaaagttcca aatttgctct tcatctccct
    18481 tactaatggc ctgaccaatc acttccaaac gttccttgaa atcctcaatt ctatccagaa
    18541 tggtctcgct attggacaag agaatggagg tccacattcc tggctcgctt tccgcaattc
    18601 gggtcatatc tcgaaaacca cctgccgcaa agcgccttgc catctcatgc tcttgagcat
    18661 agaccgcagt ctgctccatg agactagaag ccaaaatatg aggaaaatgg ctaatctgag
    18721 aagtgacacg atcatgctcc ttggcatcaa tctcgataaa acgagcatga agacctgaaa
    18781 gcagatcctt catttcctta agcgtgtcct gacttgtcag gcttgaaggt gtaaagatat
    18841 aataggcatt ttcaaaaaga ttgacatctg ccgaagcagc ccctgtcttg tgactaccag
    18901 ccatgggatg ggccccgaca aagcgaacag acttgccagc caaatactgc tccgccgcat
    18961 ccacaatggt tgacttggtc gaaccagcat ctgaaataat aacgccttct cgcaaatcca
    19021 aattggccaa ctccttaatg aaagcaatag tttgtttgat tggcaagctg aggataatga
    19081 catctgccaa aggagcaaaa ctagcaaaat catccgttgc acggtcaatc ataccttctt
    19141 tcaaggcgat atctctcgaa gcttgactac gattataacc taaaatttca taatctggat
    19201 gatcgcgttt gataccaagt gccatagagg ctccaatcaa cccaagacct gcgatataga
    19261 ttgtttttgc cataggaact ccttaatagt tctttgtata gtctcggtgt ttggctaccg
    19321 cttcttttag ttcctcaaga ttatctgatg agaatttttc gaggatttct tgcgccagaa
    19381 ccgttgctac aactgcttcc atgaccattc ctgcagctgg aagagcagtc ggatcacttc
    19441 tctccacggt tgccttgtaa ggttcgtggg tttcgatatc cacactcata agaggtttat
    19501 aaagagtagg aatgggtttc atgaccccac gaacaacgat gggttgccca ttagtcatac
    19561 caccttcaaa accacctaga ttattggtac ggcgagtata accgtcttct ttagaccaga
    19621 gaatttcatc cataacttgg ctgcctttac gataaccagc ctcaaagcca agaccaaatt
    19681 ccaccccttt aaaggcattg atagagacaa cagcttgagc caatcttgca tccaattttc
    19741 tatcccattg gacataggaa ccaagaccaa ctggaacgcc tccgacgact gtctccacaa
    19801 ccccaccgat ggtatcacca tcacgtttga tttggtcaat atagtccttg atttcctgtt
    19861 ctcgttcttg gttgacaata gaaacttcag actgggcagc tctttgctta atttcagcga
    19921 ctgtcagatt ttcaggaaca tctatttcct taccaccaaa gaccacgaca tggttggcaa
    19981 tctccatatc cagctcagcc aagaggcgtt tggctactgc accaactgcc acccgcatgg
    20041 tggtttcacg agctgatgaa cgctccaaag aatttcgcaa atcatcaaaa cggtacttaa
    20101 tccccccaac caaatcggca tgacctgggc gaggatgagt aattttccgc ttgcttttaa
    20161 ggcggtcttc aatgtcctcc gcagacatga tgtccagcca tttctggtgg tccttattga
    20221 tgacatccat agtaataggc gcccctgtcg tcttcccgtg gcgaacaccc gaagtaaaga
    20281 caacctggtc actctcaatc ttcatacgac caccacgacc gtagccaccc tgacggcgtc
    20341 taagatcctc attgatatcc tcagctgtca atggaagtcc agctggaatt ccctcaataa
    20401 tagctgttag acgggggccg tgtgattctc ctgcagttaa atatctcata cactctcctt
    20461 attttaccaa gtagtctttc atctcttcca gagaaactgg gtgaatggtc gctgaaccaa
    20521 gctctggcac caagaccaat ttcaaggtgt taccacgcgc tttcttgtca tgagtaagag
    20581 cctgataaag cttgtcaact ttccaatttt catagtcaac aggcaagccg aatttctgac
    20641 acatctctgt gatagattgg gtaatgccag ctggcatgag gcctttttcc tcagcaacct
    20701 tggaaatctg taccattccc atggcaacag cctctccatg catgaccttg ccataaccgg
    20761 cagtcgcttc gatggcatgg ccaatagtgt ggccaaaatt gaggtaaaga cgaataccat
    20821 tgtccaactc atcttcaacc accatcttgc gcttcacctg acaagaatgt tcaatcaagg
    20881 tctctgcatg ttccaaaata ctctcaacag aaccattcag tcccgtcaag agagcccaca
    20941 gttctggatc ctcaatcaag ccatacttga taacttcacc catcccttca atcaactctc
    21001 tttttccgag ggtttcaaga acaagtggat caatcagaac cccatctggt tgggcaaagg
    21061 tccccaccat atttttagca aatggtgtgt taacgcctgt ctttccaccg atagaagaat
    21121 caacctgagc tgtcaaacta gtcggaatct gaacaaagtg aataccccgc atataggtag
    21181 aggctacaaa gccagccagg tccccaacaa cgccaccacc aagagcaacg attccatcgc
    21241 tacgagtcag accttgcttg actagaaatt catagacttt ctgaacagta gttaaattct
    21301 ttctttcttc accttctaag aaatcaaaaa cagctacctg aaaaccagca tcttctaggc
    21361 tgagcttgac cttctctgca tagagagagg ctacatggtt atctgtcaca atgactacct
    21421 tttgcggttg ccagagttct cgcaaccact gaccagcctg ggccatacaa cctttttcaa
    21481 tctgaatatc ataaggatga tgaggaatat cgattctgat tttcatagga gagtctccct
    21541 ttctttattg atatttttct gttaaagact gccaaatctc ttctgtcggc attttcttgc
    21601 ctgtccacag ttgaaaagct tctgcagctt gatagagcaa cattcccaga ccattgactg
    21661 ctggattgcc ctgacttcta gcccatttca aaaacggtgt ttcaaagggt tggtatatga
    21721 tatctgcaac taagagagtt tctggtaaga ctatgttttc aggaacagga gaggattggc
    21781 catccatgcc cacactggtg gcattaacta gcaaatccga ctcggcaatc cttgcttgca
    21841 gttcagaaac atattctaaa gcacacaaat ccactttaaa gcctgtctgc tcctgtaact
    21901 tgtctaggta aggtcttgtt ttttccatag aaacggaacg aacaaagacc gaaatctgac
    21961 tgacgccatc caaaatagcc tgtgccaaga ttgatttagc cgcaccacct gcacccagca
    22021 gggtcatctt tttacctgaa attgtaaaag aaggcaagca cttaaaaaat cccttgccat
    22081 ctgtattata tccaattaaa ttgccattct cattgacaac cgtattaacc gcaccaatca
    22141 agcgcgcttc atcgctcagc tcatccaaat aaggaatcac ctgctcctta tagggcatgg
    22201 acagattgat gccaaacatc tggtagcgac gaatattggc cactgtttct accaagtcac
    22261 tcgcttcaat ctcccaagcc acataagcac cgttggtagc tgtcgcctca aaggctctat
    22321 tgtggatgaa gggagaaata gaatgcttaa taggattggc aacaactgca gctaaacgtg
    22381 tatagccatc aagcttcatc caaaatctcc ctgatttttt tcatgctagc tagagaaatc
    22441 tgcccagggg cactaacctc atccagactg gcaaaagacc aactcgaacc agtcacatcc
    22501 gcagtgatac gagagacctt gcccacctta cccatagaaa tggtcacata ttcctgttca
    22561 ggattgagcg ttttaaagcc tcgtgtatag ttcatcaagt ctaagacatc ctgctccgtg
    22621 tgagccatca ccgcaacctt aacaagtttt ggatttagga tcgtcaactc tgacaagatt
    22681 tccatcatgt tctcaggtgt ttcttggaaa ttatggtaac tcaaaacaag atttgggaag
    22741 tccagcattt cctcaaaaac atccttgtag ctatagtact caaaatcaat atagtctggt
    22801 tgatagagtt gcgcaacttc cttgattaga tggatatact cttctggaga aaggtcgatt
    22861 tctccacctt cggagcgagt tcgtagcgtg aaaaccaact cacggcctgc gaatttttca
    22921 aaaatggctg gagctacctg caaaatcgct tctttaggca gatagtcggc acgccattca
    22981 atgatgtcgg catccaggta cctcgtggca tccagagcct gagcctcctc taaacttctt
    23041 ggcattactg aaacgattaa tttcatttac taaccttcat actaatcacc ttgaggtaat
    23101 tactactttc atctttttta ttataggcaa aatctgctgg aagaccatat ttgtttaaaa
    23161 tctggtaact tcttcctgca aagcctttat caatttgttc tgtaaatttc tgacgggaaa
    23221 cattggcagc attggtactg gcaatgataa tccctcccgg atttaaaatc tcaagactct
    23281 gggaaatcaa cttgtgataa tccttggcca cagagaaagt ttgtttttta ttccgagcaa
    23341 agctaggcgg atctaggaca atcacatcgt aggtcaagtt tttgcgtttg gcatatttga
    23401 aatactcaaa gacatccatg actataaaac gacgctcgtc tgtgctgagc ccatttgcct
    23461 gaaaatgcgc ttgagacaat tctcgtgaac gtttggctag atcaacagaa gttgtctggc
    23521 tagctcctcc catggccgca gctactgaaa aagccgctgt gtaggaaaac atattgagca
    23581 aggatttacc catagccaag ccgtcaacta aactaccgcg aacctcatgc tggtctagga
    23641 aaattcctgt catcaagcca tcattcataa agacttgata caggacacca ttttctaaaa
    23701 cagtgaaaaa gtcaggtgct tcttgaccat aaacatgggc agattcatag tccaaaccct
    23761 taaagcggat tttctcataa gcccctaaaa cctcagggaa aacctgtcta aaggcttctg
    23821 atatagtctg acgaatctga taaacataag agttatacca agaaaagacg gcgtagtcgc
    23881 cataaaggtc cactgtcaga cccccaaagc catctccctc ttgattaaag agacgaaagg
    23941 cagttgtcaa atcatcttga tagtaggcgt ttctcttttc tttggctttt ctaaacaacg
    24001 tttcaaagaa agcttgattg aaggccacct tgtctttgct gacaaaccag cccaagccct
    24061 tgttttgctg agaaaggtag gcagtcccaa gaaagtttcc ttcctgaccc tgcacctcta
    24121 cttcctgatc cttaagattg acattctcaa gatcactggc ttctagtaaa actagcccct
    24181 tagcaagctt cttttcaacc cttttgctga ctcttattct attcataact accattatat
    24241 caaactttta gacaattctc aaaaaagaaa ctacccttgc ttttttactc ttcttttaaa
    24301 aaatggtata ctagacttcc tgcaaaacta ggaagtaaat gtgtaagaat cacaataaaa
    24361 aatgctcttc cgtcttggag gagcatttct ttttatcaac gaaaatcaaa taacaaacta
    24421 tgaaactagc ctcaggttaa ctgtgagatt ataggtagag aggttgaatc agcaatatgt
    24481 gtctgtcaaa tttagtgaca aaggtagtag aagaaagatg aagaaataaa tctgcttcag
    24541 tagatatctg gaaaatttga ttttatagaa aagccttttg ttacaaactc aatatactat
    24601 caataaataa tattatagaa gcaacaataa ttaaaatttc acctatttgc atcattctat
    24661 ttcgaactct aaatatatgt tctatcaaaa atacttggat cacacacatt ataggaatta
    24721 acgtttttga aattgaaaaa tatcccaata aataaactat aaacaacaat aatagaacta
    24781 tattatattt cttattcaaa acattcctcc ctatattttt gattaccaat cttaatcatt
    24841 tacaactaca ttctaacaaa ctataaaagc gtttgtcgaa ttgaatttat caagcaagca
    24901 accaactatc tcatcttttt tctatttctg ccaatatgcg tgacaggtaa taatgatagc
    24961 caaaaatagc aagagcaagc aagacgataa gagctcctac tcccaagttg atggcaagga
    25021 taggggagag agactgaacc aagaatatgc tcccaattac aagggccatc aggattgcac
    25081 tataaataaa caataaaact atggcgacta tgccatttga acgattcacc aggtccgtaa
    25141 tgctactcca attggttgac agatttttaa cgtccttaaa gtaatggtgg caagaaagga
    25201 tgacactggc aatgatccag actacaagaa ggtaaatcat cgaaaggatg gacaagccta
    25261 gatatagaga aagaccgagc aaagtcagaa ctggtaaaaa ggactgaaca gcaaagataa
    25321 tccaaaattt cactttcaca taacgagcaa agtcaaaggg taaactcttc agaaaatcaa
    25381 cattttccct ctccaaggac aaggcaattg aatgcaggct ggtgatattg ttattgacaa
    25441 ctgctataaa cactcctaca aaaaacaagg gtaaccagta tggaggatga atgtctggaa
    25501 ctatctgaga atctcggatt ttggaaatca gactgatcat catgagataa ggaaggaaag
    25561 cacttgtaaa aagcactgta atcacaccag tcccctatcc caagagggtg aggtggtagc
    25621 gtaaaaccat acggaaaaag ccctttttag tagttgaaat cctctccttg ctgcgacgtt
    25681 cttttttgac cttctcctca ctgttaagca ggatcacgtc ataaaaacga ggaaggacct
    25741 tctttttggt cagataaagc aggaagagag ttagtcctat ccaagcgagc agacccacta
    25801 aggcttctgt cgaaaaaggc tccactgcta ttttgtaaaa gatatgaaga ggataaagga
    25861 gaaatggaat gtctctaact ttgtcaacaa tacttccaaa agtcgactga agaaagaaga
    25921 taaatattaa aggtatgaga actcctatcc caatcatcac attcgaaaaa atagactgat
    25981 actttctgaa gaccctagtc tgagccaaga aatgtactgc cactaccgtc actaaagtaa
    26041 cagagacaaa taataaggtc aaggacagta gcatcaaagg caaacccagc caaagagaag
    26101 gagctagact aatatagagg gctagaaaat aagctaggat tggtacaatt ccagttagag
    26161 ctggcaagag gacagacaga cctttggcca ttataatctc tgattcttta aaggcatagg
    26221 gcctatagga ggccaggtcc ttactctcat aaaagacatt gtaaaaggca gtgaaagaag
    26281 ttgaaaaggc cagcaccagt aaaatagcaa ccatcgagct aaaataaata ggtatttcct
    26341 caaaaggaaa atgaatggct atattactaa aacagatgag catcaagaga ctggaaaaaa
    26401 tgtaagaact taggactcta gcagaaacat ttactttttt cccaggattc ttagcctgct
    26461 tctttcgtag attagccaga ttagcttctt gagatgaata gaggatattg atatcaacta
    26521 attttttaat gaccttgaga cgcatccgca acctcctctt ttctaccagc aagactaagg
    26581 tagatacttt ccaaaaactg gtctgggtgg tctttcctca agttctctac actaccacaa
    26641 tagatcaaat gccccttttt caaaatagca atccgatcac agacttgctc ggctacctca
    26701 aggacatgag ttgaaaacaa gaccgtcttg cctttttgtg catgttcctt catcatttgc
    26761 ttcaaatcaa aggcggcctg gggatccaaa ccagtcaagg gttcgtccaa aacccaaata
    26821 tcaggagcag acaagagtgc cccaatgaca aagactttct gacgcattcc gtgagaaaga
    26881 gtttcaataa cctgatagcg gttttcagca aaatcaaaaa cgttcaatag cctagctaga
    26941 ctagtctcca agtcagagct agtcagatca taggatgaag cgatcaattc ccaaaattca
    27001 ttggccgtta agcgtaaaaa taagtcaggc gagtctgcta cgtagccaat ctttcgtttg
    27061 atcgccaagc gattttccga taactcctga ccgtctacca aaatacgacc actgctgggt
    27121 gaaatgatac tgactaggga ttttatggtg gtcgattttc cagccccatt atgaccaatc
    27181 aagcccataa tctctccatt ttcaatctgc aaattgagat tactcaaggc ctctttatca
    27241 ccatacaact tactaacatt ttgaaattca atcatgggac aactcctatc tttatctgta
    27301 ttatacatcg ctatactagc actttgatac aaaaaaatca atactttatt ttaagtagtt
    27361 aaaatagttt ccttctatct tacgcaaacg tttgcgccga gagatacttt atgatagaat
    27421 aaagaacaag attgacaagt aagaggaaac atcatgcaaa atcaaacact catgcaatac
    27481 tttgaatggt atctgcccca cgacggtcaa cactggacgc gtctggctga aaatgctcca
    27541 cacctagctc atctggggat cagtcacgtc tggatgccac cagccttcaa ggcaaccaac
    27601 gaaaaagatg tcggctatgg ggtctatgac ttatttgact taggagagtt caaccaaaaa
    27661 gggactgtcc gcaccaagta tggtttcaaa gaagactatc ttcaagccat tcaagccctt
    27721 aaagaacagg gaattcaacc tatggccgat gtagttctca accacaaggc tgctgccgat
    27781 aacagggaag cctttcaggt tatcgaagtt gatcctgtag accgtacagt tgaacttgga
    27841 gaacccttca ccatcaatgg ctggactagt tttaccttcg atggtcgcca agatacctat
    27901 aatggcttcc actggcattg gtaccacttc accggtacag actacgatgc caaacgcagt
    27961 aaatctggga tttatctgat ccaaggggac aacaagggct gggctaacga ggaattggtc
    28021 gataacgaaa acggaaacta cgactacctc atgtatgccg acctagactt taaacatcct
    28081 gaagtcatcc aaaacatcta tgactgggct gattggttca tggaaacgac tggtgtagct
    28141 ggtttccgtt tggatgccgt taagcatatt gactctttct ttatgcgcaa cttcatccgc
    28201 gatatgaagg aaaaatacgg tgacgatttc tatgtttttg gtgaattttg gaacccagac
    28261 aaggaagcca atctggacta tctcgaaaaa acggaagaac actttgacct tgtcgatgtt
    28321 cgtctccacc agaatctctt tgaagccagt caagctggcg caaactatga ccttcgtggc
    28381 attttcacag atagcctggt tgaactcaag cctgacaagg ctgtgacttt tgtcgacaac
    28441 cacgataccc aacgaggaca agcccttgag tctaccgttg aagaatggtt caagccagca
    28501 gcctatgccc tcattttgtt acgccaagac ggccttccat gtgtctttta cggagactac
    28561 tatgggattt caggccagta tgctcaagaa gatttcaaag aaatccttga ccgcctccta
    28621 gccatccgaa aagacttggc ctatggagaa caaaatgact actttgacca tgctaactgt
    28681 atcggttggg tacgttcagg tgctgaaaat caatccccaa tcgcagtcct tatctcaaat
    28741 gaccaagaaa acagcaagtc aatgtttgtc ggtcaagaat ggactaatca aacctttgta
    28801 gatttacttg gtaaccacca aggtcaagtt acaattgatg aggaaggtta tggacaattc
    28861 cctgtctcag ctagatccgt aagtgtctgg gcagtcaata ccatctaata gctcataata
    28921 accaagctag gtccaagcgg atttggcttt tttgtattca caaaaagacc tacccaaatg
    28981 gatagatctt tacttgatta caatttacct gctactgcat ccaacaattc ttggatctta
    29041 gcttggttgc ttcctcctgc catggccatg tctggtttac caccaccacg tccatcgatg
    29101 attggtgcta attctttgac aaggtttcct gcatgaaggt cttttgtctt gcttgctaca
    29161 aggacattga ctttgtcacc gatagcggca actaggacaa gaagatcaga gtagtctttt
    29221 tgtttccagt tatctgcaaa agtacgaagg gcaccggcat cggatacaga cacttgacta
    29281 gcaatgtaac gatgaccgtt gacttcctta gcatctttga agatatcgcc tgcggctgca
    29341 gctgcggctt tttctttcaa ctcagcattt tctttttgaa gttgacgaag ttgttcttga
    29401 agtccttcta ccttgtgagg tacttccttg acttgaggtg ctttcaaggt tgctgcgaca
    29461 gctttaagag catcctcttg ttcacgatag gcttcaaagg cttccttacc agtcactgcc
    29521 aagatacggc gagttcctga accgattcct tcttctttga caattttgaa gagaccaatc
    29581 tcagaagtgt tgccaacatg agtaccacca caaagttcaa tagagtagtc accgatagtc
    29641 acgacacgaa cttccttgcc gtatttctca ccaaagaggg ccatagctcc catttcttta
    29701 gcagtgtcaa tatccgtttc aactgtcttc acttcaagtg cttcccaaat tttctcgtta
    29761 acttgctgtt caatcgcacg aagttcctca gcagttactg cttggaagtg ggtaaagtca
    29821 aagcgaagga attcaacttc gttaagagat cctgcctgtg ttgcgtggtt tccaaggata
    29881 ttgtgaaggg cagcgtgaag caaatgagtc gcagtgtggt ttttcatgac acggtgacgg
    29941 cgattgctat caattgccaa ggtatattct tggttcaagg caagcggtgc aaggacttca
    30001 actgtatgaa gggcttgacc atttggggct ttctgaacat tggtcacagt agccacaatc
    30061 ttacctgact catccaagat ttgtccgtag tcagctacct gtccacccat ttcagcataa
    30121 aatgacgttt ccgcaaagat aagagaggca gttccttctg aaacagctcc tacttctgca
    30181 ttgtcagcaa cgatagctac caatttagaa gacaattggc tagtattgta gttgaagaca
    30241 ctttctacag tgatgttttg aagagtttca ttttgcatac ccattgagcc acccttgaca
    30301 gctgacgcac gcgcgcgttc ttgttgttct ttcatggctg cttcaaaacc ttcacggtct
    30361 acagtcatac cagcctcttc agcaatttct tcagtcaatt caactgggaa cccataagta
    30421 tcatagagtt tgaagacatc tgaaccagcg ataacagatt gacctttttc tttcaagtct
    30481 gctacaatgc cttgggcaaa gtgttgacct gagtgaaggg tacgggcaaa tgattcttct
    30541 tcgctcttaa cgattttctc aataaagtca cgtttctcaa gcacttctgg gtagtagctt
    30601 tccatgattt ttccaacagt tggaaccaat ttgtaaagga aaggctcgtt gattcccaat
    30661 ttttgaccat gcatagaagc acgacggaga agacgacgaa gaacataacc acgaccttca
    30721 tttcctggaa gggcaccatc accgatggca aatgaaagtg aacggatgtg gtcagcgatg
    30781 accttgaagc tcatgttgtc gccatcttgg tcataaacct taccagacaa tttctcgact
    30841 tcacggataa tcggcatgaa gaggtccgtt tcaaagttgg tcttagcccc ttggataacg
    30901 gccaccaaac gctccaaacc agcgcccgta tcaatgttct tatgtggcaa ttccttgtat
    30961 tcgctacgag gaacagcagg gtctgcgtta aattgtgaca aaacgatgtt ccagatttca
    31021 atataacggt cgttttcaat atcttctgca agcaggcgaa gaccgatatt ttctgggtca
    31081 aaggcttccc cacggtcaaa gaagatttct gtatctggtc cagaaggtcc cgcaccgatt
    31141 tcccagaagt tgtcctcaat tggaatcaag tgacttggat ccactcccac ttcaatccag
    31201 cggttgtaag aatctttatc gtctggatag taggtcatgt aaagtttttc agcagggaaa
    31261 tcaaaccatt cagggcttat caaaagctca taagcccaag tgatagcttc gtcacggaag
    31321 taatccccga tagagaagtt ccccaacatt tcaaacatgg tatggtgacg cgcagtcttc
    31381 cctacgtttt cgatgtcgtt ggtacggata gccttttggg cattggtaat acgtggattt
    31441 tcagggataa tggtcccgtc aaagtatttc ttaagggttg ctaccccaga gttgatccac
    31501 aaaagagttg ggtcatttac aggaaccaaa cttactgatg gttctactga gtgacctttg
    31561 gtcgcccaga aatcaagcca catttggcgt acttgtgcac tagatagttg tttcatattg
    31621 tctccttatt tacttgttta atgtgattgg ctttccagca tttccacata gtcaatcgcg
    31681 acacagaggg aaatgactag gtctgcataa gcgtcttcaa gaaccgttac ggtataggta
    31741 gaggtcagat ggaagagttc cttcttaatt tccgcaatca actgatcgcg atcatccagc
    31801 aatttgaaat tcaaatccca gatattgccc tcgatacgaa gacctagatt atcaaactca
    31861 tacttatctc gccaaaaggt caacttctta cgaatgacaa aactcgagcc atccagaagc
    31921 tgaatctcaa aacgaggaag caaggtcaag atttctttac tgatctgact gacttgttca
    31981 ccagccgcat catagatggt aaaagttttg ggaatcttaa aaaatgatcc ctccacctga
    32041 taggcaattt ctcccctgtc atccttgata gcgaagcgtt cgcctccaag acgaaacttt
    32101 tgtttgacaa gaaatgtttt catcaacacc tccaaaaatc aaaagacaag ctcatatcac
    32161 gaagggcgaa aaaccgcggt accaccttca ttcaatgaac ttgtcattct cttgttctta
    32221 tgcaattgta tgattgagta gcatgacttc ctagcttaga tggctcgcag caccgccatt
    32281 tctctggact aagacaagtg aaaatcaatt ctcaactttc ttattatatc gtttttttaa
    32341 tcttgcgtca actggaaatg atctccgttg aattagacca attccctaca tctctgatta
    32401 cttttccagg atatattttt tcttactgcc gtttttcttt ttatcccaaa ttttcatatt
    32461 actaaacaca gctactagaa tatttccaaa tataaaggtg cctatcaccc aatatatgga
    32521 ctcagttgtt aggtattgtc gatccaagcc atcctttaaa tggaatagta tagcagtttg
    32581 gttaacaatc ataaaggttg gccagaaact tttgttgaaa aaagtagaca ttttcattat
    32641 ttgttgccgc tttctgtaag gttaatactc aataaaaatc aaaaagcaaa ctaggaagct
    32701 agcctcaagc tgtacttgag tacggcaagg caacgctgac gtggtttgaa gagtataggc
    32761 ttagtatact actaggcaag caaataagca aataaacaac tagaatagaa aaagataggg
    32821 ctctaaaaac tgacttctat tccttaaaaa cgaaccagct tgactgattc gtcttcttac
    32881 gtttatctcc tacttccgat acattttaaa ctgtaggaag aggtcgctat atttccctgt
    32941 ccatttatgg tcaaatttct cataaatttc taggtgtttc atggtttcaa catcgggata
    33001 gaaggcctta tcttcctttg tttcctctgg gagcaattcc ttcgctggta tgtttggtgt
    33061 tgaatagccg acatactccg cattttggag agcattttca ggtttcaaca taaagttgat
    33121 aaaggcatag gctgagtctt ggtttttaac tgttttggga atgaccatat tgtcaaacca
    33181 aagattgctg gcctctgtcg gtaccacata acgtagattt tcattttttt ctaacatttg
    33241 gctggcttca ccagagaagg tcacgccgat tgcaacgtta ttctgaatca tatagccctt
    33301 catctcgtcc gcaacgatag ccttgatatt tggagtcagt ttgtagagct tatccactgt
    33361 ctcttccaac tgctgcagat ccttggagtt gaggctgtag ccgagggaat tgagtcctag
    33421 tcccagcacc tcacgcgccc catcaaagag catgatagaa ttcttatact ccggcttcca
    33481 aaggtcatcc caatgctcag gcgcttcatc taccatggtt tcgttgtaga caattcctaa
    33541 ggttccccag aagtaaggga tggagaattt attacctggg tcaaaggact ggttgagaaa
    33601 ctctggtccg atattttcga ttccttcaat ttttgaataa tcaagcggaa ccaagaggtc
    33661 ttcgtccttc atcttgttaa tcatgtattc acttggaatg gcaatatcgt aggtcgttcc
    33721 accctgcttt atcttagtgt acatggcttc gttggagtca aaagtctcgt actgaacttg
    33781 aattcctgtt tcttctgtaa actgagtcaa gagttcagga tcgatatagt ctccccagtt
    33841 atagataacc aatttttgac tatctcgact attgatttta ctatctaaat gagtcgcaat
    33901 tccccacaag acaaggataa tcgctgcaat tcctgctaaa aatgaataga tttttttcat
    33961 gcttgctcct ccttctcacg agagataaag taataaccta caactaggat aatactaaag
    34021 agaaagacta gagcagacag ggcattgatt tctaaggaaa tccccttgcg agcacgagag
    34081 taaatctcga ctgatagggt tgaaaagcca tttcctgtta caaagaaggt cacggcaaag
    34141 tcatctaacg aataggtgaa ggccatgaaa taaccagtaa tgatagacgg agtcaggtaa
    34201 ggaagcatga tttccttgaa catctgaaat tgactagctc ccaagtcata ggccgcatga
    34261 atcatgtcgc cattcatttc cttgagtcga ggcaagacca tcaagaccac gataggaatg
    34321 gagaaggcca cgtgactaga tagaacggtc aaaaagccaa gtgaaaactt gagttgggta
    34381 aagagaatca agaagctagc accaatcata acgtcaggcg caaccatgag gatattattg
    34441 agtgatagaa aggcttcttg gtatttctta cgagactggt agatgtaaat ggcaccaaaa
    34501 gtcccgataa tggtcgctat caaggctgat aggaaggcca agaaaaatgt ctgagccaaa
    34561 atcagcatga gtctcccatc tccaaacatg gtttcaaagt gagtccagct aaaacctgta
    34621 aagctattca tatcatcacc agcattaaag gcatagccaa tcaagtaaaa gataggcagg
    34681 tagaggacca gaaagaccag tcccagataa aggttggcaa attttttcat cgttctctcc
    34741 tttccttagt cacccacatg gtgatgaaca tggtcaggat gagaatcaca ccgatggttg
    34801 aacccatacc atagttgtca ttggttagaa aattctgctc aatagccgtc cccaaggtga
    34861 taacgcggtt cccaccaatc aaacgggtca gcatgaagag actcaaactt gggataaaga
    34921 ccgactgaac cccacttcgc acaccgttca tagatagagg gaagatgaca tgacggaagg
    34981 tctcccactt agttgcacca aggtcataac tagcattgat gagattatta tccatgtcgt
    35041 ctaagacatt gaaaatcggc aaaatcataa aggggagctc gatgtagctt gcgacaaaga
    35101 taaaggaaaa atcggtaaaa agcaactgtt gtgaaccaat tccgataaat tccaagaatt
    35161 ggttaataga gccattttga ccaaaaatcc cgataaaagc ataggcttta aggagcaaat
    35221 tgatccaggt aggaaggata atcagcatga gccagagttg acggtgcttg agacgggtca
    35281 aaaagagggc tgttggatag ctgataagca aggtcacaaa ggtcacaatc cctgcataaa
    35341 gcactgagtt gaaactcatt ttgaggtagg tcaagttttg tgacgcaaag taagatttat
    35401 aattttctaa actaaactgg ccttcaatgt tgaaaaagga ttgtccgaaa atcaagacca
    35461 agggtgccaa tacaaagagg gcaatccaaa gcatgtaggg cactacaaag agtttagagc
    35521 ttgttttctt catctctttc ctcctcgatc gcattgatca gacctgcttc ttgctcttcg
    35581 atttccacgt attcttcgat acgagcatcg aactcttctt cggtttcatt gagacgcatg
    35641 atgtggatgt cttctgattc aaagtccaga ccgatttcct cacccacgat ggccttacgg
    35701 gttgagtgga tcatccattc atttccaagt tcgtcatagg cgataatttc ataatgaact
    35761 ccacggaaga gctgggtgtc gaccttaact tggagtttgc cttcttcagg aagggtaatg
    35821 cgcaagtcct ctggacgaat aacgacctca acaggttcat ttggcttcat cccaccatca
    35881 accgcttcaa agcgtttgcc gttaaattcg accaagtagt cctcaatcat ggtacctggc
    35941 aagatgtttg actccccgat aaaggtggca acaaagtggt tgattggctc atcgtagatg
    36001 tccacagggg ttccagactg gacaatctcg ccatcattca taacgaaaat ccagtcactc
    36061 atggcaagag cttcttcctg atcgtgagtg acaaagacaa aggtaatgcc caatcgttgt
    36121 tgtaattcac gcaattcgta ctgcatgtct gttctcaatt tcaagtccag cgctgataaa
    36181 ggctcgtcca acaagaccac acggggttgg ttgatgatag cacgggcgat ggccacacgc
    36241 tgacgttgtc ctccagaaag tttgcggatg gaacgttttt cataaccttc caactgaacc
    36301 atcttgagaa cttccgctac acgctgctcg atttctttct tatcaatttt acgcaagcga
    36361 agtggaaagg caacattttc aaacacattc atatgtggga acaaggcata ggattggaag
    36421 acggtatgta cgtcgcgctt gttggttgga atatcattga tacgaacacc gtctagcatg
    36481 atatctcctg tcgtcgcatc cagtaaacct gcaataatgt ttaggatagt tgatttcccc
    36541 gaaccagatg cacctagaag ggtgtagaat ttcccttctt ccaactcaaa gttgatgtct
    36601 ttgagaacct tggtgttgct gtcttcaaaa actttagaga cgtttttgaa ttcgataatt
    36661 ggttttttca attggcataa attccttctt tttcatagat taaccgatcg gggctctgtc
    36721 aggtccccac tacctcttgc agggagtaaa accacctgca tacatcttcg ctaccgatag
    36781 gctttcaccc aagatccgga cttctctttc aagcgtaata cctgagtgtt ccttgacttt
    36841 ttcgataacc gattggatca agtcctcgta gtctttggcc gttccatctg cgacattgat
    36901 cataaatcct gcatgctttt ctgacacttc tacgccaccg atacgatagc ctttcaagcc
    36961 agcttctgaa attaactgac ctgcaaaatg cccgactgga cgcttaaaga ccgagccaca
    37021 agatgggtat tccaaaggtt gcttgagttc acgtaggtgc gtcaagcggt ccatttcctg
    37081 cttgataacc tgatgggttc ctggagctag ggcaaattta actgacaaga caactgcacc
    37141 agactcctga atagctgaat ggcggtaacc aaaagccaag tctttagcag acagggtttc
    37201 gatttctcca tccttggtca agaccttaca agactgcaag atgtgagcaa tctcgccacc
    37261 ataggcaccc gcattcataa agacagcacc gccaacgctt cctggaatac cacaagcaaa
    37321 ctcaaagcca gttaaactat gacggagggc aatgcgagtt gtttcaatca agttagcccc
    37381 agcttctgct tcaatggtat agccatcaac agaaacgtta ttgagcttgt cacacaagat
    37441 gacaaatcca cgaatcccac catcacgaac gatgatattg cttgcattgc caagaaccat
    37501 ccaagggata ttttcttggt tggcaaattt cacaaggcga gccaactcaa aacgatttcg
    37561 tggaaagacc aaataatcag cctctccacc tacttttgta taactatagc tatgcaaggg
    37621 ttcctgaaaa cggatatcaa ttccttctaa gatttcaagc attttttctc ttacagacat
    37681 gtcactcttc cttttccaaa attcattcca ttataccatt tttagagaca tttgacgacc
    37741 ataaaaatac cttgtttgga ttttgcataa gaaaaagagg ttcccccctt tttatgattt
    37801 tttacaaaag atttccttgg ttccataggc gaccagaacg agctccagtg ctagaatcac
    37861 ttcaaccaag actggatttg tcaaccagcc tacttggaaa agagatggtg ccagatcaaa
    37921 gaaggcatgc aagccatagg ctgttaggag ataaatccat ttcttctggc gaacagcttg
    37981 gtaaacccaa actgtcaaaa gtaattggaa accaagcgcc aagattcgct caaaaccaag
    38041 caaataaatc tgccagaccg aaagtgactg aatggttttt aacatatttt cagacagtaa
    38101 ttgcataacc tgtggattct gagtttgaac tgccgaaaga acaatgtaaa gattgagtaa
    38161 actagtaagg cctagaaaaa tcaactccaa gccaccatgc cccagtccat aggccaaggc
    38221 gtctgccttt tccaaacttc tctttttctc aaaccatttg aagaaaacaa gacgagccgt
    38281 ttcctcaaaa aatgctgcca tggctaggcc atagataata tagataagcg gatgatcttg
    38341 caagagggca atactaccgt ctttttgagg gtgcaaaatc aagatatgca ccagtttttc
    38401 caaaatctgc gaagagacaa agaaagcgac tgcacccaag cccaagacag ctagattaat
    38461 ctggtatttc tttttggcaa accaaatgct tcctatcaga aaagctagca acagcaacat
    38521 ggtaataatg atatgaatgg tcattttctt ctcctattct gccttttcaa tatctttttt
    38581 catctcgtca acattgaact tagcaaacaa gtattgacgg tcttggactg ggaaacgttg
    38641 gtccaactgg tcaactgctc ccacctcgat aatgccttcc ttgatgacaa aatccatgac
    38701 atgtccaccg aaggtcaaat catctgatat gaagtgcaga tggtagcctg ccacactgac
    38761 cccatggaaa atctcaggcg tccagaaacc aacaatagtc cccgcaacat tgtcacgact
    38821 atattccggt tgatgggttg cgacatcagc aaacttggta tcgggtgttg acttaggaat
    38881 catacgcaca tgcatatgta aaaattcccc ccgaatcttg atagagcgga aaagattttc
    38941 cccatcataa taagactcaa ttcgttcttt caattccttg tctgtcatct caaagcgctg
    39001 gcggaaaatg acctctgcct gatgcggtac cactgcagcg taaggaataa gggcatctgg
    39061 tgacacttcc acaatttctg gctggtctcc tgaccctttg gcctgataag ccttgccatc
    39121 caagacaatc aattccccat caatggaatc caaggttccc aaaccaaggt caccatgttc
    39181 tagcaattct cctactgtca tagtaccacc ataaaggcca gccatcaagg ctccaagagt
    39241 attgtattga aataatttca ctggttcctg cacgttctta tccattcact ttcttgtctg
    39301 ttattctata aatcttactc ctaagtatac cacatttgcc cctagatgtg aacgagagaa
    39361 acgttctaga cattgccaag aaggaaaaaa aagggtacaa tgtaacaaaa tcaagggagg
    39421 tctggaatga agaaacaaag caagtacaaa gaggtcgttt cctatctgaa aaatggtatc
    39481 gagtctggac gatttccgac gggtagtcgc ctgccttcta tccgtcaact gagccttgac
    39541 tttcactgca gcaaggacac cattcaacga gccctgctgg aattacggca cgaacaatac
    39601 ctctatgcca agcctcagag tggctactat gtattagaac aagggcaaca tcaagaccta
    39661 gaaatcgagg ttaccgacga acatgccagt gcctatgacg atttccgact ctgtgtcaat
    39721 gaaaccttga ttggccgaga aaactacctc ttcaactact atgacaatca agaaggatta
    39781 gaagacctaa gacagtccat tcacaaactc ctctttgagc aagctctcta ctgcaaggct
    39841 aaccaactag tactgacttc tggaacccaa caagccttat ttatcctctc tcaaatatcc
    39901 tttcctagac aagccaagga aatcttggtg gaacagccaa cctaccatcg gatgaatcgc
    39961 ctcttgattg cacaggggct ggactatcaa acgattgaac gaggcattga tgggattgac
    40021 ttggaggagc tggaaggcca cttcaaaaca ggaaaaatta aatttttcta caccattccc
    40081 cgatttcact atcctctggg acattcctat tctgagcaag acaaacgatc tattcttaac
    40141 ttagctgcca agtatgatgt ctatatcgta gaggacgatt atctgggtga tttggactcc
    40201 aagaagggcc aaaccttcca ctatcttgat acagaggagc atgtcattta tatcaagtcc
    40261 ttctcgacca gcctttttcc tgcccttcgt attacagcac tcattcttcc aaatgctatc
    40321 aaagaagcat ttgtggccta caaaaatatc ctagactacg acagcaacct cattatgcaa
    40381 aaggccctgt cactctatat tgacagtcaa ttgtttgaaa aaaatcgttt ggctcgcttg
    40441 accaatcatg aatcttacca aaaacaaatc gaggaaagga taactaaaac accttgtccc
    40501 cttcctcatt atcccctaca cgatggttta ttgctagacc tgagacagta tcctaaaatc
    40561 gccagtctca aacacagtca actgggcttg gacttctttg aagaggccta tttgagcacc
    40621 tgtccttatc aatttgccaa ggtgtcccta gacaatctgg aaaatgtttt aaactattta
    40681 aaagcagaat tggaatgaca tccaactctg ctttttctta ttcttcaact tcagttagac
    40741 ttgctgcttt ttcaagatag ctttggtaag ttccttcatc cttaagtttt tggatgacct
    40801 tgtctaccac ttctttcaaa tcatcactat tttttctaag agcaacggca ttggcgtcgc
    40861 cgtccttcat cttcaagctg acagttgcga cagctaagcc agcgttttta gcagcataac
    40921 taagtgcaac aggctcatcc atatgaacag catctatttt tccagcctgc aattcattga
    40981 ctgcttcacc catattagtt agggaagtta attgagcttt tggcaattgt tccttgacca
    41041 ttgattctgg aacagtccct ttttgggctg caatattagc actttctagg ctagttaaat
    41101 ccttgtattt ttccacatca gccttacgaa ccaagaaact aatcttgttt tcatagtatg
    41161 ggattgaaaa atcaaagact tcttttctct cgtcagtagc actaattcct gcaactgcta
    41221 ggtcagcctt accagtttga agactggtca aaacattgtc aaaactcatg cttaagattt
    41281 ccaacttaac cccaagttca tcagcgatag cctgagccat gtcgatgtct gcaccgacta
    41341 cctggttctt tccatcaacc aatgattgaa attcaaaggg tgcatagtca ggactggttg
    41401 ccacaactaa tttccccttt tgcttaatgg cctcaacagc tgactgagaa ccattagaac
    41461 ctgactggca agctactaag aagaaacttg caagaaaatt acataaaaca aatatccatt
    41521 tttttgattt cataaataaa caacctttct gttaattttg tataattata acgatatcca
    41581 agttacttgt caagtgtttt ttaaattttt atctcaaaaa tattttttcg ttcaaaaaaa
    41641 ggagccatca gttgatttca agctcctttt tatacagaat taaactattt tatagttcga
    41701 caatcttacc tgtttcaaag tagacaaccc attcacagat atttttagca tagtcaccga
    41761 tacgctccaa gtaggaaata acttggaaat aatcacgacc cgtaacaatg gcttctggat
    41821 ttttcttaat ctcttcagtc gcaaggtcac ggatagtttc aaaatagtgg ttaatttgct
    41881 catccatgga ggccacccgg tatgcgtcgt caacagaacc attaagataa agatcaagtg
    41941 ctgcttccac aacgctttta acttcacgtc ccattttttt aatttcttcc tctacagctg
    42001 ggatgcgttc ttcccccttc atacggatgg ttgcctgggc aatggctaca gcgtgatccc
    42061 ccatacgctc cacatctgat acagccttaa ggacagtcaa gactgtacgc aaatcttgag
    42121 agactggttg ttggagtgcg atcatttcaa atgatttctt ttccagtttc acttcgtatt
    42181 catttacttc tgcatcatct tcgatgacct cttttgccag gtcacggtca tgcgtgacaa
    42241 aagcacgtac cgtacgattg atttgtgaga gcacttcttg tcccatagcg tagaactggt
    42301 tatgtaattt ctctaaatct tcttcaaatt gagatcgtaa catctttcat ctccttatcc
    42361 aaattttcct gtaatatagt cttccgtttc cttgtgttgg ggatcaagga acatctgctt
    42421 ggtatcatta aattcaatca aatctccatc taggaaaaat cctgtcttat cagagatacg
    42481 tgaagcttgc tgcatggaac gggttaccag aagcatggtg tacttgtctt ttagaccata
    42541 caaggtttcc tcaattttac cagctgaaat cggatccaaa gccgaagttg gctcatccaa
    42601 gaggatgatt ttaggactag ttgccaagac acgggccacg cagacacgct gctgttgacc
    42661 acctgacaat ccaatagctg aatcatatag acgatccttg acctcatccc agatagaggc
    42721 accttgcaag gctttttcta cggcttcatc cagaacctgc ttatccttaa ttccattgat
    42781 acgaagcccg tagacaacat tctcatagat agtcataggg aaaggattag gttgttggaa
    42841 aaccattccg atttccttac gtaattcaac cgtatctgta cgcggactgt agatgttgtg
    42901 accattgtac accacggatc cagttgtggt cacctctgga ttgagatctc ccatgcggtt
    42961 gagagacttg aggagggttg acttccctga tccagatgga ccaatcaagg ctgtaatttc
    43021 cttaggttgg aaagataggg aaacactatt caaagccttc tttttattat aatatacgga
    43081 caggtctgat acctgtaaaa tcgcatctgt catacggttt cctttctaac caaagtgacc
    43141 agatacatag tcattggtgg actgtagctt ggcattttgg aaaatagttg cagtcttgtc
    43201 atactcaatc aaatcaccca agtaaaagaa gcctgtatag tcacttgcac gagcagcctg
    43261 ctgcatatta tgcgttacaa tgatgatggt aaagtttttc ttgagctcaa acatggtctc
    43321 ttctagttgc atggtcgcaa tcggatccaa ggctgaggct ggctcatcca ttaagaggat
    43381 atctggctta acagagatgg cacgagcgat acagagacgt tgttgctgac cacctgataa
    43441 ggtcaaggct gacttgtgga gatcgtcttt aacctgatcc cagagggcag cctgacgaag
    43501 ggaggtttct acgatttcat ctaggacttg cttatcctta actccagcac gttcatgcgc
    43561 aaaggtaata ttacggtaaa ttgacttagc aaatggattg gggcgttgaa aaaccattcc
    43621 aatgtgttta cgcatttcat aaacgttgat ttctggacgg ttgacatcaa ttccacgata
    43681 gagaatctgc ccagttactt tagcaatatc aatagtatca ttcatgcgat tgagactgcg
    43741 taagtaggta gatttccccg atcccgacgg accaatcaaa gctgtaattt tatttctttc
    43801 aaattgcata tcaatcccct taatggattc atttttacca tagtaaacat ggacatcctt
    43861 agtagaaagg gctacttttt cttcaggaaa ggtaaggata tgcttctcat cccagttata
    43921 tgttgacatg gcttctcctt taggcagcgg ttaatttctt gtgtagatag cttccgaact
    43981 tacgagctcc aaagttaaaa atcaggataa agatcaggag cacagcggca gaacctgctg
    44041 atacaatggt tccatctgga atagtgcctt cactattgac tttccagata tggacagcca
    44101 aggtttctgc ttgacggaag atagagatgg ggctagtcac actgaggata ttccagttag
    44161 accagtcaag agctggcgcc gattgccctg ctgtatagat cagagctgca gcttcgccaa
    44221 agatacgacc agatgccaag acgacacccg ttacaatacc tggaagcgct tctggaataa
    44281 caacatgaac cactgtctcc cagcgagaaa tcccaagagc cagaccagcc tcacgttggg
    44341 tatggtgaac gtgtttcaaa ctatcctcta cattacgcgt catctgaggc aagttaaaga
    44401 ctgtcaaggc caaggcacct gaaatgattg aaaatccata ctcaaactgg actacaaaga
    44461 tcaagtaacc aaagagaccc accaccactg atggtaaaga ggacaagatt tcaatacaag
    44521 tccgcacaaa gttggtaaca ggaccttttt tagcatattc agccaagtaa atcccagctc
    44581 ccatagaaag aggtacagaa ataatcaagg taatgaccaa taggaaaaag gaattgtaaa
    44641 gctgaatgcc aatcccacca cctgcttgaa aagcagaaga ccttccagtc aagaaagacc
    44701 aagagatatg gggcaagccc cgaaccaaga tatagagaat caaggaagcc aagattgtca
    44761 caatgatgct agcaatcgta tagaggacag ctgttgcaag tttatctaat ttcttagcgc
    44821 gcataatttt tctttcctct ttctttcgta atcaatttaa tcacactgtt aaaaactaaa
    44881 ctcatcaaga gcagtaccaa ggccagtgac cagagaacat tattatttac agttcccatg
    44941 acagtgttcc caattcccat agttaatata gaagttaaag ttgcagctgg tgtggtcaag
    45001 gaagttggga taacagctga gtttccgaca accatctgga tagctaaagc ctcaccaaag
    45061 gcacgcgcca tcccaaagac cactgcagtg aaaataccag aacgggccgc cttcaagatc
    45121 acacgccaga tagtctgcca gcgagtggct cccatagcga aacttgcctc acgataataa
    45181 cgaggaaccg cacgcaagct atccgttgtc ataaaggtta cggtcggcaa aatcatgaca
    45241 aagaggacgg aaatccctga caaaatccca aaaccagtcc caccaaagac actgcgaaca
    45301 aagggaacga cgacttgcaa gccaataaat ccgtacacta ctgaaggaat cccaaccagg
    45361 agttcaatag ctggttgcaa aatcttcgcc ccttttggtg atacttcggt cataaaaact
    45421 gctgcaccaa tagcaaaggg tgttgcgata agggctgaga gaatggtaac gataaaggaa
    45481 cccaaaatca taggaagggc accaaattct ttactagaag gattccaagt tcctcccaaa
    45541 agaaagtcaa agatattcac accattgaca aagaaggtcg acaagccttt ttgcgctacg
    45601 aaaaccaaaa tcatggccac aaggatgact atcaaagaaa gacaggcaaa ggtcaaacct
    45661 tttcctaatt tctccagacg agaattcttt gatggaagca acattttctt agctaattct
    45721 tcttgattca ttattgtctc ccttccaaca ctgtcacagt tccggcagca tctttttcaa
    45781 ccttcatttc cttaatcgga atatacttca atcctttgac aatcccttct tgggtctcat
    45841 ccgagagaac aaaattgaga aattctgcag ctaactcatt gggctgcccc aatgtataca
    45901 tatgctcata agaccacaag ggccaattat tgctacttat attttctgga cttaagtcat
    45961 agccattcaa cttcatgctt ttgaccgaat catctatata ggtaagagat aaataagaga
    46021 tagctcctgg actttttgat acgattgatt ttaccgctcc atttgaatcc tgctcctgac
    46081 tttgcatggc agactgacct tccataatga cagtatcaaa ggtagcacga gagccagagc
    46141 cggctgcccg attgataaca gagatgggta agtccttacc accaacctct ttccaattgg
    46201 ttacctcacc tatgaagatt tgacgaagtt gctctgtcgt taggttatca acatcaacct
    46261 ccttattgac aatcagagcc aagccagcta ccgcgacctt gtggtcaaca agagcagaag
    46321 catcaattcc gtctttttcc tcagcaaata catctgagtt tcctatatca actgccccag
    46381 actgaacctg ggacaagcct gtaccagaac ctcccccttg gacattgacc gtttttccaa
    46441 catggatcgt gccaaattca tctgccgcta cttcaaccaa gggttgcaag gcagttgagc
    46501 caacagccgt tatggattct ccacgatcaa tccagctagc acagcctact aaacaagccg
    46561 tcagccaaaa agcgataaga gacagagcaa gcttttttct ttttttcact gtttttctcc
    46621 tcgaaaataa ttatgaatac tgtgaatttt ttaagtagtt ctttatgagt tgacgcatga
    46681 attcttacca aatttctgcg caattgatta tttatataat ataggctata ttactctttc
    46741 ctaacctcct tttttcatat gtggataaaa tctcttgtct atcccttccc ccattgtcac
    46801 ccattatagt catttcgtgt ctctttttcc cctttttaat gcaagggaaa ttactctcct
    46861 tagatgataa tccaaaagct agaaaggtat ctcaaatctc tctactctcc cagactagtt
    46921 tacaactaaa aggaaaagat tctattttat gagaaatcta gtttacaagc ggtaagaacg
    46981 ctaataacta aacttcttgt actctttgaa aatctcttca aagcagtgtt ttgagctatc
    47041 tatggctagc ttcctagttt gctctttgat tttcatcgag tagtaaaact acatgtgatg
    47101 gcaatcaaga tatcaagaat catcctacta aaaaaatcca tactttcact ataacataga
    47161 ataagatatt tgactagcat tttcatttga atctgaggcc ttttggaaaa taatttttca
    47221 aaacatttcc agtaaccttt gcaaagccca agccattgcc tttaaccaaa acttggtacc
    47281 aaccatttgg cagactttct gccagctgaa cggtttctcc agccgcatac ttgacaaact
    47341 cttcttggcc aatttcaacc gactgttcga cctgactcgg tttcaaggct aaaccaagag
    47401 cgaaactggg ctcaaagcgt ttcttcttaa aagtacccag atgcagtcca ttgcgagcaa
    47461 tcttgagctt ccctaaatct ggcaaaagtt ctggcaagag ataaagctgg tctccaaaaa
    47521 tctgcaagat acccggtaga ttgaccttca aatggttttg ggcaaattcc tgccacaagg
    47581 caacttgttc acggctgagg ttactcttac ttgccttaaa tttaggagct ggattgttac
    47641 ccttaaactg tagatgggca acaaactgac cctctccctt aaactgatga gggtacatcc
    47701 gagccgtttc tggcaggtca ataccagcta ccattccatt gatatgctct actggcaaca
    47761 agtcaaaatc atactcttcc agcaaccaat tgacaatctc ttcgttttcc tcgggtgccc
    47821 aggtacaggt cgaataaacc agacgaccac cttcagctaa catggtcact gcatcctcca
    47881 gaatttctct ttgcaagcta gcacattgac tcggataatc taagctccaa tagtccatag
    47941 catcaggttg cttacgaaac attccttcac cagagcaagg ggcatcaaga acgattaagt
    48001 caaaatagcc tttaaagacc ttgaccaagc ggtcggcaga ttcattggtc accacgacat
    48061 ttgtcgctcc aaaacgctcc atgttttcaa ccaaaatctt agcccgtttg cttgaaattt
    48121 cattggaaac aagtagcccc tcccctgcta gataggctgc cagttgagtt gatttgcccc
    48181 ccggtgcagc agccaagtcc aagaccttca taccaggact gggttgggct acttgagcca
    48241 ccatttgagc agcaggttct tgcgaataaa ctaaacctgt agcatgctca ggcgatttcc
    48301 ctgaaacctt cccatagtgg ccccaagggg tttgagtaat ggcatcagaa aaggaaagtt
    48361 gctcttcttt taagggattg acccgaaagg ccgaaaccgc ttcctcctca aaagaggcaa
    48421 gaaaatctct tgcctcatct cctagtattt ctttatattt ttcaacaaat ccttctggaa
    48481 atttcattta agttcttttc ctttcgtaaa tataggactg aatttcctcc tgcatctcaa
    48541 gaggcaccat catgaccggc tgtctggttt gaaaatcagg agcttcacca aaaagggtca
    48601 caacccgata gcccagactt tcccctaaaa tactagctgc ggcataatcc catggttgca
    48661 gataggtgag ataggtcaac aaacgccctg acaaaatctt ggcaaaacta atggccgcac
    48721 ttccatagac acgaacacca agaaccgctc ggctcaaatc agccagcccc cattcattgg
    48781 tttccagcat accactattc cctgcaatga gaaaatctcc aagtggttta gttttaaaag
    48841 aagctagggg cctatcattt agacaaactg gaaattcccc accaccgtgg taacaatccc
    48901 ctttgaccac atcataaatc agaccaaact gtccctgacc attttcaaaa taagccatca
    48961 taacagcaaa atcttcctgc tgggctacaa aattattggt accatcaatg ggatcaatga
    49021 cccaaacctt gccctcttga accgaggctc gcagacaacc ttcttcagca caaatcttat
    49081 cctcaggata acgggacaaa atctcaccaa ccaagagttc ctgaacttct ttgtccagtc
    49141 tggtcaccaa atctgttgga gaggacttgg tttcaacacg caagtcttcc tgcatatggt
    49201 caagaatgta ctgacctgct ttcttaacaa gctctttagc aaattcaaat ttacttttca
    49261 agagaaatct ttcctttccc tttttctttg gcagcctgaa ctgctcggta aagtgaatag
    49321 ccactaaccg tttcaaattc tcgtcccaaa cgtttctctt cgctcttgct tggcacgacc
    49381 gctttgaatc ccttatagga gtccagtaac tttttagcct ctactttgcc ttcataggca
    49441 gcttcaacat cattaaaaaa agaaagcact gaagcaagtt cttcagtgct ccacgacaaa
    49501 tctagtgggt aactatactg tttgttcatt aactaatacc agctctcatt cttgcttctt
    49561 ttagttcttg cttacgataa ctacgaggga gaaaagcacg aatctcatct tcattaaaac
    49621 cgatttgcat acgcttggca tcaataataa ttggacgacg caaaagacta ggatactgct
    49681 caatcaaatg aagcaattcc gataccgaaa tactctctac atcaatattc aatttttgaa
    49741 aaatttttga acgagttgaa atgatgtcat cagtaccatt ttcggtcaag gaaaggatgt
    49801 gttgcaattc ttttcttgtt aaaggactgg tcataatatt gtgttccaca aagggaacct
    49861 tatgtttttc taaccaggtc ttagccttac gacatgatgt acagctcggt gatagaaata
    49921 gtgtaatcat gcttttctct tcttatctat actttgctac ttctattata caaaaaaata
    49981 aggcgcttga ctagggattt ttagaaaaaa agcctatttt ttcaggaaaa ataggctgtt
    50041 tgcgaacgat tgacacaatt ggatttggtt aattcactct taacgatggt tttaaacgat
    50101 atatatattt atatatgtaa attaaaaaca tctttccttt cacttcctac gacttttcag
    50161 acacagatag ccaaagaagc tttcatagag ggcaaaaaag aggaggaagg catgaagaaa
    50221 gaaggtctct ggcaaaatca taataacagg atccttggct ggatcaaaaa gccaggtatc
    50281 atctcccaca aagagaattt gatggaaaag agtaaagaat tggtcaaaac caatcaaaac
    50341 tcccccaagt ccaatcatca caggtaagac tactagagcc aggagacttt ttcgataaag
    50401 agacaaaaag tcctttttca caatcctatt gacaaagaca tagaaacttg gcagtgtcac
    50461 tagagctact agctgaacca aatgaaagag attcttgacc actgcgaaat ggtgcaaacc
    50521 agctgctgac gaacgaaaat caggcatctg taagacctga ctaaaaggat tggtcagata
    50581 attcatcaag atatgaaaat tgtattgaat ggtttctggt tttagataga ctcgattcgt
    50641 taagtttagc cactgaatct ccataggata gaaaatccaa gccagataaa tggtcagaag
    50701 gattgagagg gagaggagaa agagcataga gccccaaaag gtcaatttag ttttcatcaa
    50761 aatcccactc cgcaaggcta gaaaccacat gtgtcggtgc gattggcagg ccagctactt
    50821 cttctgcctt ggtaaaacct gtcgtcacca agagcgttgg aatgccattg tcaatcccag
    50881 cccggatatc agtcaaataa ttgtccccaa ccatgattaa ctcttcacgt tccaaaccta
    50941 agtgctcaac tgccttgtcc ataatgatgg cattgggttt tccgatataa accggcttca
    51001 ctcgtgtcgc tacttcaagc agcgtaatca gtgagccagc acctggcaaa agaccacgtt
    51061 ccgtcgggat gttgaggtca ggattggttc cgataaaatg ggcacccttt tgaatagcaa
    51121 gagttgctgt ggcaaatttt tcatagtcga cttgccaatc cagaccaact accacgtagg
    51181 caggtttttc cttgtcttcc acataaccag ccgccttgat ggcttccttg agtcctgctt
    51241 ctccgacaac atagacggtc ttttcaagcc ccaaatcatt catatagtcg atggttgcca
    51301 aagtcgctgt gtagacagtc gataggggcg tatcgatatt aaaattctga gccaacatct
    51361 ccttaacact ctctggagtg cgggttgtat tgttggttac aaagagatag ggaatgtccc
    51421 gcttttgcaa ttcatgaaca aaagtctctc cagcagggat ttggtctttc cccttataaa
    51481 tggttccgtc taaatcaatt aaatagcctt tatatttcat ctatttctcc ctaagccttt
    51541 tttatttctt gccaagtaat gattgcttgg gcattgataa ccccatcact tgtaatttca
    51601 tgcttgcttt ccagtccagt ccgttcaaca gccgatgtaa tcaccccacc tggtcgaact
    51661 tccttgacat acttgaggtt gattttcttg ggaatatagt gggtcaaaaa atccgctccc
    51721 atgacctcaa aaatccagtc taagtattta ctgttattga catgaccatt catatccaag
    51781 tcgtaaaaac gaacatggta atccttgctg atcgactctt ccaaggactc atacttcggt
    51841 ccacggataa gttttttatc aaaatcagac tggtaaggag ccacaatctc aggttcaaca
    51901 gcatggactt ttcgactgtc gcggtccatg agaacaaagg tcgccatcat atggatgagc
    51961 tcctgccccg cttcattata aatagtaaag cgacggtagc aaaaaagtcg attgtagctc
    52021 aaggcttccg tttcgatggt aatttcttcc gcaaaacgag gcaaacgaac cacctcaata
    52081 tcatattcta cgataatcca gaccagatta tagtcttcca aaatggcctt atcactaact
    52141 cccagttcaa tcgactgcat ccctgaaact tgcagtgaca gcaaaattac atctggaagt
    52201 ttgatatgac cgttcatatc agccatatca aaaggaattt tcattttcat ttgataagtt
    52261 aagcccatga tcctactcca aaataaatcg ttccgctaca gtatctccca aaaagagacc
    52321 tctctttgtc atgcgaacgt ggtcaccctc aatctgcatg aggccttgtt gaaccaaatc
    52381 tctgacaatt tctccataaa gtccagcaaa agactgtcca aatttttcct caaatcgcgc
    52441 catggaaacc ccggatttct tgcggagtcc caagaacatt tcttcttcca tttgctcctt
    52501 ttgactcagg tgatcttctg taatacaagc attgccttcc tcaaccgcac tgagataatg
    52561 acgaatggga ccatgatttt tatagcgtac tccattgaca taaccagatg cccctgcacc
    52621 aataccatag tattcagcat tgtcccagta catgagattg tgacgacttt caaagccggg
    52681 tttggagaaa ttagaaatct cataatgctc aaaacccgct cgctccagct ctgcaatgat
    52741 gtactcaaac atctccgctt ctagttcctc cttaggcaga ggcaatttcc cacgtcgcat
    52801 ccgattcata aagaccgtat ggttttctaa aatcaaacta tacaaactca tgtggggaat
    52861 atccagtcca atggctttag ccacattttc ctttacttgc tccatggtct gaccaggcag
    52921 agcataaatc aaatcaatgg agatgttgtc aaaaccagcc agtttcaggc gatcgatatt
    52981 ttcataaata tccttctcca aatgactgcg cccaatcttt ttcaacatct tatcatcaaa
    53041 ggtctggaca cctagcgaaa cacgattgac agccgaattt ttcaaaacag ctatcttatc
    53101 cgcatccaaa tcgcctggat tggcttcaat ggtcaactct tctaagacag acaagtccaa
    53161 gtttttagtc aagccattca gtaaaacctc cagttgcgga gccgacaggg ctgtcggtgt
    53221 tccaccaccg atataaaggg ttgacaactt ttcaatatca taagaacgaa actcttccag
    53281 cagatgctct aaatagctgt cgactggctg atttttgatg aagacctttg aaaaatcaca
    53341 ataataacaa atctgggtac aaaatgggat gtgcacatag gctgacgttg gttttttctg
    53401 catagtaatt attataccac aaagactaga ttccagataa aaatcaccat ccccagatac
    53461 atagtccgtc cggagatggt gatggtttat tcttctgtta tatcaatcac aatctcttct
    53521 gagtcatcaa gagcttcggc tttttcttgc cattgctcct tgagattatt taattgattt
    53581 tttgatgctt ctgtcgcttg aaaagcatag gatttagctt gagcaagtat actgtccaca
    53641 gtgatttcac ctgactcaac ctgttctttt gttttcagaa caaaatctgt agcctgctcc
    53701 ttaacttctg tcagtttttc acagacttgc tccttggcat actccggatc ttctctcaaa
    53761 tcatctagaa aatcttgagc ctgactgcaa acttgtttgc ccttatcact tgttaaaaac
    53821 aaggcaagag ctgcacctga aacggttcct aaaaggattg aggataattt acccataagg
    53881 attctccttt tttatttttt gaaaaattta cttgcaagac gaagagctga cagacttgca
    53941 ccagtcttga gtgtttttga accagctgat gaagctttct tgctcaagac acgcgcatgg
    54001 tcattgaggt ctgaaacaga tagagataaa tctgcaacag cactgaagag tggatcaatc
    54061 gtagccacct tgacattgat atcatctgcc aagacattga ccttagccaa caactcattg
    54121 gtgtgatgca aggtcacatc cacatctgaa gtcaaggttt taatcgtctt ttctgtttca
    54181 tcgatgacac gaccaagctt ttgtacagta atgatcagat agaccaaaaa gacaatcaaa
    54241 gctagggcaa caagaatata tgcaacttct aacatttagt tttcctcctc tgtaatatag
    54301 taaggggcct tctttcgatt ttgataaata acgatcatta taccgagacc gataaggaca
    54361 actgacagcc attgggacac tcgaaggccg aagaacatga gactatctgt tcgcatacct
    54421 tcgatgacca tacgaccgaa accataccaa atcaagtaaa aggccgtgat atgacctcgt
    54481 ctgagactct tccatttccg tctaaaaatc agaatcaagg caaagccaag cagattccat
    54541 agagactcat aaaggaaagt cggttgacgg tagctcccct caatatacat ctggtcacgg
    54601 ataaagccag gtagataatc cagattatcc actgttgcac cataagcttc ttggttaaag
    54661 aaattacccc aacgccccaa actttgagca atcataacgc taggcgccgc aatatctaga
    54721 aaatcccaag tattgatgag tttacggtca gcaaagatat agagcacaag agccccagtt
    54781 atcaaaccac cgtaaatggc caaaccacca ttccaaatgg caaaaatctc tcctaaattc
    54841 tgactatagt aatcaaatcg gaaaataaca tagtagagac gagctcctaa aatagccaag
    54901 ggaaaggcta ctaagataaa atctaaaata tcgtctggta tgatcttctt tctaggtgct
    54961 tctttcatgg tcaaataaac cgcaagaatc aagcctgtca caatacataa ggcataccaa
    55021 cgaatggcta ggggtcctag ttgaatagca attggatcaa gcattttgca cctcatttcg
    55081 agcgatgaga cttgtcagtc gttcgtcgaa caaacgggtc gcatcaaagc ccatttcctt
    55141 ggcacgataa ttcatggcag ctgcctcaat cacaacagag atattacgac ctgttttaac
    55201 tggaatacga atacgaggaa tggctacgcc agaaacttca agttcctctg cattgtttcc
    55261 aagacgatca aaggtcttat gcgtatcgta attttccaaa tagacagcaa gctgaacctg
    55321 tgaagaatcc ttgacagcac tcgcaccgta gagactcata acatcgataa taccaacccc
    55381 acgaatttca atcaagtgtt tcaaaatttc agctggttca ccccagagag taatctcatc
    55441 cttggcaaag atatcgacac ggtcatctgc taccaaacgg tgaccacgtt tgacaagctc
    55501 aagacctgtc tcgctcttac caattccact atctccctga atcaagacgc ccatcccata
    55561 aatatccatc aagacaccgt gcacactggt acgttctgcc aaacgagaat ccagatagct
    55621 agataactct ccagataaac gactggtagc tgcacggctg gttaaaatag caatcttaca
    55681 ttctctagca gcctttaaca tctcctctgg aaccaccaaa ccacgggcaa caatgactgc
    55741 tggtgtctca gatagaaaca tttttttcaa aacttcataa cggctgttgg aaggcatgct
    55801 gatcagataa gaccactcct tcatccccaa aagttgaatc cgctctggtg tgtagtagtc
    55861 aaaatagcct gtcatttcaa gaccaggtcg cgtaatatcc gctgtattga tttccttttc
    55921 aagcaactct ggttcaccat agacaatatc tagtctaagc ttttcaatca cttcttttac
    55981 taaaaccgac atcatttcct ccttcaaatg agttcttctc tctattatat caaattgtag
    56041 gaggaagttt cagatttttg caggctttgg agtatttatt taaaagaaaa aggactagat
    56101 ttctctagcc tttcattcca attagaattt tttacgttta cgagctactt ctgatttacg
    56161 tttacgtttt acagaaggtt tttcatagaa ttcacgtttg cgtgtttctt gaagagtacc
    56221 agctttagta accgcacgtt tgaaacggcg aagtgcgtcg tcaagagatt cattcttacg
    56281 tactactgtt ttagacattt ttttcactcc cttcaagttc gatatctatt tcattctaca
    56341 cgtaaaagga ataattgtca agcaaaaatg ctgtttaatt ttgatttttt cttccattta
    56401 tacaagagtt gaaagcgttc aatagaacat tgctttttta tttttcgagt aagctaagcg
    56461 cttcagcatc tgcgatgatg gttacatcag ggtgattttg gaggctactt gcaggtaggt
    56521 tctcagtcac tgggccagat actgttccgg caatggcttc tgctttcgac tcaccgtaag
    56581 caaaaagaat aatagacttg gcatccaaaa tgtttttaat ccccattgaa atagcttggg
    56641 ttgggacgtc ttcaatcttg gcaaagaagc gtgcattggc ttcgatagta gactggtcaa
    56701 gttctactag atgcgtttga ctgtcaaatg gagtaccagg ctcattaaag ccgatatgcc
    56761 cattgcgacc gattcccaag atttggaggt caactggatg gtcagccaaa atttggttgt
    56821 agcgttcaac ttcagcttca gcattgtcct taacaccacg aggcaagaaa ctttctttaa
    56881 atggtttttg gttgaacaag ttttcttgca tgaagtaacg ataagactgt ggattgtccc
    56941 catcaaggcc cacatactca tcaaggttga cactggttag atttgaaaaa tcaaggtcac
    57001 tctcaacaat ttccttgtaa aattcaagtg ggctacttcc tgtcgcaagt cctagagttt
    57061 gagctccatt agccaatttt tccttcaaaa tctcaaaagc aacttttcca ccttgaactt
    57121 ggttttcaac tttaataact ttcatctttt catcctccat ttctgtctat atttattata
    57181 tggtatagac caatttttgt caagtgaaaa cgatttaatt tctaaaaaaa gagcgtccaa
    57241 acttgaaacg tgttataatg gataggatta gaacttagaa agaatgaaca gatatatgaa
    57301 tacagctgat tttgatttcc acttgccaga ggaattgatt gcccaaacgc cccttgaaaa
    57361 acgtgatgcc tccaaactcc tcatcgtcaa ccgtgagaca ggagaaatgc aagataaaca
    57421 cttccactct attattaata tgctggaacc tggtgatgcc cttgtcatga acgacacccg
    57481 agttctccct gcccgcctct atggtcaaaa agtggagaca ggaggtcatg tggaacttct
    57541 cctccttaag aacactagtg gagacgagtg ggaagttctg gctaaacctg ccaaacgcct
    57601 caaggtcggt actcgtatca gctttggtga tggccgcctc agcgctgtcg ttacagaaga
    57661 attgacccac gggggacgca ttgtccgctt tgaataccaa ggaattttcc tagaagtctt
    57721 ggaaagtctg ggagaaatgc ctctgccacc ttatatccac gaaaaattag atgaccgtga
    57781 acgttatcaa accgtctacg ccaaggaaag cggctctgct gcagcaccga ctgctggtct
    57841 tcacttcacc aaagaactgc tggcagaaat ccaagctaag ggtgttcatc tagtctatct
    57901 gactctccat gtcggactcg gaacctttag acctgtttct gtggataatc tggacgaaca
    57961 cgaaatgcat tcagagttct atcaactttc tgaggaagct gctgccaccc ttcgctctgt
    58021 caaagaaaat ggtggtcgcg tcatcgctgt cggaaccact tctatccgca ccttggaaac
    58081 tattggttcc aagtttgatg ggcaaatcca agcagattct ggttggacca atatctttat
    58141 caaacctggg tatgagtgga aggtcgtgga tgccttctca accaacttcc atctgccaaa
    58201 atcaactctg gtcatgttgg tttctgcctt tgcaggccgt gaattagtct tagatgccta
    58261 ccaccatgcc atccaagaac actaccgctt cttcagtttt ggtgactcca tgtttattta
    58321 ttgagaaaga atttctctaa atcttctaat accaataaat cgctaagata ttatttcaaa
    58381 gaacatctac aattgaaact ctagctagct gtagaagacg cctagtacat tgaaattaaa
    58441 atgcttcccc ctagcttcga aaatattgcc atagattgcg ttgactctcc aaattgattc
    58501 atctatattt tatttcagct tcctatattt tcttcgctgt ttgtaaatca aaatgcaaga
    58561 cacatgagta gcaccatatt tgttactctt atctgtcctc tcaagagact attatgagtt
    58621 atttcagaat cattcactac tttgaccctg actctcctta gtctcaaaat caaagactta
    58681 tactcttcaa aaatctcttc aaactgcgtc aacgtcacct tggattatat atgtgactga
    58741 cttcgtcagt tctatctaca acctcaaagc agtactttga gcaacctgcg actagttttc
    58801 tagtttgctc tttgattttc attgagtatt aaacaaaaag tgaacaaatc tgaattctaa
    58861 tgtacagaag actaggcttg ttcacttttt tatagtcgct ataagatgac cttatctata
    58921 gctttttata tataattata tataattata tattcagaca tactattatc aattttgtcg
    58981 cagggaggaa tctgttaacg cacccattca ccattatcat tgactctata gccatctata
    59041 cttgtattga ccgctaactc acccgatgca tttacataat accatttacc accaacttgg
    59101 aaccattgat tgactttcat agaaccgttg ctgttgaggt agtaccatga accattaact
    59161 tgtacccaac ctgttgccat ggaaccatca gtattataaa aataccacat accattttct
    59221 tgtttccagt ctgttgttgg agcaactgct ttagctggtt ctactgctac atctgttcct
    59281 tggttagatg taacagatac aggatacgaa ggaatagatg attgctcagg aacaacaact
    59341 ttttcaggtt ctctcgtccc tctccttata cgtcttttta ccatctcttt agtaatttga
    59401 cgagaagtag tttcttcaat tgttccatca cgttcatcta cagtatagat tgtagtaaga
    59461 gtaatttacc aatttctcct acttcttcta cttcttgact tttatcaaga gttgggtcat
    59521 cgagatattc tgtttcgatt ggaatttctt ggacaagaac ttggggcttg gttccttttt
    59581 taacaactct tgtttgagag tcttcttttt gacttaaagt actctcagtt acttgtccac
    59641 tctttccatc tacatcataa gttatcgttg taactgtttt cccattcttt cctagagtaa
    59701 tctcttgctc ctgtcctgca gaaaggtcat tgtctgcttc atatttagta gcacatggaa
    59761 caagaacttc ttcaaccttg cttttagctg gaactttgat aactgtatcc gtggcttgtt
    59821 ttctatcaac agtaacctgt tcggtaacat gaccagtctc tggattaaca tcgtaggtcc
    59881 ttgtcgtagt tacatagcca tcctctccat caattgtaac aggattttca ctacggtctt
    59941 ttgtttcatc tttttcataa cgaattcgcg tacttgaaat tttcttggtt actaccttag
    60001 gtttagtcgc tacttttaca ataatacccc cattgtcagc gtcatcatac tctattccct
    60061 cttctttatc tctagtatca tctctgacat attgaatccc atcagcagca tgaacaaaac
    60121 ttgtattcag attcctccta aaaataaagt tagcccgatt accgcagaac caaaaatctt
    60181 tccgagttta cgtaatgcat agcgcttatt agtattagat tttgccatta catcctactt
    60241 ctagtatagc atcttttcta tcaaacgtta aacaatatac tttatatata aaatagactt
    60301 agaatgatat attgattatt gaactaacac tttaactata tcgtaatcaa tctcatatat
    60361 aaaggattgc agacatctta tctaaataca tgctaatata tttagataca aacattccaa
    60421 cttgataatt ttcactcatc tttcatcatt ccttatacaa ctatgcagta taaatagaat
    60481 agttttctca tcagaatgag actattttaa tattagataa tttgatagaa aaaacatgaa
    60541 taaaattggt tgaatttaat tccctaactc gatagaggat tctattttaa atttaacaac
    60601 agctaggatt acactataaa aagtacatta ccacctgttc ggctggagaa tctagtcgat
    60661 tagctccctc ttagttacaa gcttaaagcg attttttaac taatactaaa ccagattaaa
    60721 gaaggaacta gaacatctgt cttgtactaa tcaatatgct attttaaagt ttcaaataaa
    60781 cttggaatgc taattattat atttacaata aatagttgac ttcgatagaa acagaaaata
    60841 gaattcaaca ttcttcccta cttataccat aataaataag atccgcaaga tagccttttc
    60901 tctctacacc attaacaatg gtttgtagat aggacattcc agccttttcc atgacacgac
    60961 ctgaagctgg gttgagactg gcataacgtg ctctgacctt ttgaaaacct gcttgagtaa
    61021 aacaaaagtc caagatagct ttcaaagtct ctgtcatcat accatttccc cagtaagcct
    61081 tgcctaacac atagccaatt tcacagctta aatcagcctc gtctatctta acgatgctga
    61141 tatctcctat cacttgctct gggttttctt ttagacaaat ggcccattta taatagttga
    61201 gattagtata ggaagcaacc caattgcgaa tcgagtttcg agtgatttcg atatcaggat
    61261 ggggatccca ggtaacatag gtcagattct cagcagatga agcccaattt tgaaacatgg
    61321 cttctgcatc actctccaca aatcttctta aaatcaaacg ttctgtctgt aatatttgcg
    61381 taccgataga tttcatgatg ctacctcact tccttatttc tatgctcgta gtaaaaaggc
    61441 tcaactcagt aacagctaga aaacgagttt gtcttctaat ttcttgacgc agtcgctgcc
    61501 tggtttgaaa tgcgctctag caagcttttt caaacctagt catcgttgca ggggtaagac
    61561 gatgaaatcg aactcttcga gttaccgaat ctgcctcatt ttcttatttc taaactcggg
    61621 gttcaagatc ccccagacct tctctcactt tcttatttca agatgagagg ctgaaaacct
    61681 ccagtggagg tttttcttgc tttttaattt cagggcaaga agctaaaaag gtccccggac
    61741 cttcttcgct ttctcatttc taggctcagg gtaaaaacct ccaatggagg tttttactcc
    61801 caaaagtcat caaatacagt gatgggtaag tggcgtttgt gttggccttt gtgccaccag
    61861 ttttcaatgg tcgcttgagc ttctgggctg attgttttgc cttctaggta gtcgtcaatc
    61921 tctgcgtagg tgactccaag tgcgacttcg tcagctaggc ctggtttatc ttcttctagg
    61981 tctgccgttg ggattttttc ataaagggct ggctctgcgc caagtttctg caagagctgt
    62041 tttccttggc gtttattgag gcggtaaaga gggagaatat ccgcaccgcc gtcaccaaac
    62101 ttggtaaaga aacctgtgat attttccgcg gcgtggtctg ttccaatgac cgctccgcta
    62161 tgggaaccag caagggcata ctgagcaatc atacggcaac gtgccttgat attccccttg
    62221 ttgaagtctg aaacaggact acctgtcgct tcaactgcag ctgtcatggc atcagctgat
    62281 tccttgatat tcacaaccaa gctgacatct ggctggatga aggctagggc tttttgagca
    62341 tctgcttcat cagcttgcac tccgtatggc aggcggacag cgataaattt gtagctgtcg
    62401 tctcccgttt cagctcgcag ttcttccata gctaattgcg ccaaacgccc tgccaaggtt
    62461 gagtcttgtc ccccagaaat ccctagtaca aaggttttta ggaagggatg ttttttcaga
    62521 tatcttttta agaaatcaat agaacgacgg atttcttcct gggcatcaat cactggtttg
    62581 acacccagct cttggataat cgtttcttgc aaactcattc ttcttctcct tcaccaaggg
    62641 cttccttgcg catcttatca atcaagtcca tcttatcttg ccatacatca cgcgccaaat
    62701 ccactggata gtgctgcgga ttgagcacac gcttatactc atcccacaac ttgtcaaatt
    62761 ccttacgggc ataatcctga atgtcagtca aactaggcaa gttgtaaact aatattcctt
    62821 ctttgaagat atccaccaag agaggaacgg catcaaaatt acgaaccgtc ttcttgatgt
    62881 atgtataggt cggatggaac atcttgattt ctgtcatgtc gctaatatcc acaccatcat
    62941 aagtgatata gtcgccttct gacttgcctt tttcacgact ggtaatgcgc cacacctgct
    63001 tcttacctgg cgtagagact ttttccgcat tattagacag cttaatcgta ttgcgcatct
    63061 gaccagtttc atcttcgatt gcaacaatct tgtaaactgc accaagagct ggctggtcat
    63121 aagctgtaat cagcttggta cccacgcccc agacatcaat cttggccttt tgcatcttga
    63181 gattgaggat ggtattttca tctagatcat tagaagcata aatcttagcc tctgtaaatc
    63241 cagcctcatc cagttgctga cggactttct tagaaatgta ggcaatatcc ccagagtcaa
    63301 tccgcacacc cataaagtta atctgatcac ccagctcacg cgccacctga atggcagctg
    63361 gtacaccgat gcgaagggtg tcataggtat ccacaagaaa gacacaattt ttgtgggtcg
    63421 cagcgtaagc cttgaaagct tcatagtcat tgccataaac ctgtaccaag gcatgggcat
    63481 gggttcccaa aacaggaatg tcaaagagct tacccgcacg cacgttgctg gttccattgg
    63541 cgccaccaat cacagctgcg cgtgttcccc agatggccgc atccatttct tgagcccgac
    63601 gtgtcccaaa ctccatcaag ggttcatctt cgataaccga acgaatacga gctgccttcg
    63661 tcgccaccaa ggtctggtag ttgacgatgt tcaaaagagc cgtttcgacc aactgacatt
    63721 gggctagagg tccttccacc tgcacaatcg gttcattagc aaaaaccaaa tccccttctt
    63781 gggcagaacg aacggtcaac tccaacttga aattgcgaag gtaatccaag aacgccccat
    63841 gataaccaag cgactccaaa taggctatat cactatctga aaaacgcaag tcttcaagat
    63901 agttcacaat tctttccaaa cctgcaaaaa ccgcatagcc gttcttaaaa ggctgttggc
    63961 ggaaatacac ctcaaagacc gccttcttat tgtgaatccc ttggtcaaag taaacctgca
    64021 tcatgttgat ctggtacaag tccgtgtgca atgtcaaact atcatctgga tacatacttt
    64081 tcctacttcc ttagctagaa acccatgaaa attttcaaga actttcatgt attccaataa
    64141 attagtacta ttatatcaca ttttagctgg attgagaaaa gagtaacaag ctattctcca
    64201 ctctccaatt catccatatc ttgttcaaat tttttctgag cccattcgcc atagctctta
    64261 agaccaagat tgccaataaa gacccacgga aggtaaatga cataagtaat gacccaagca
    64321 gacaggtatt taaaattcaa aggattgtgc tgataaattt ctatgttgaa ttgataattc
    64381 tgcaacatca aaagagccgt aatagccaag gttaggaaaa aacaacccaa aatcgtaaaa
    64441 tgaaaacgac tatagtaggt cactcccaga taacgggcac ggttaaaaaa gtaaaatgtc
    64501 cctatgatga taacgattag cagcatatta gaattaaaaa ggcttggtgc taatactgaa
    64561 atgatataag ataggagcga caaagcgatg cagatataga aactttcaga gcccgcttta
    64621 ttgatcagtt gttcttctct ttcgtctagt aattgataat aataaaatct atttttcatc
    64681 ttcttcctcc caaaatagtt ggtctagggt tttccctaaa catctgcaaa tagactggca
    64741 gagcgagaga ctgggattgt attttcccgc ctctatcaaa ccaatagtct ggcgtgtcac
    64801 cccgacagcc tctgccagtt gaccttgtgt taaatcacgc tctacccgag ctaattttaa
    64861 ttttaaattt ttagccacct tcgtcctcct tatagtttta atactcatct actctttaaa
    64921 aatccaaact aacacaagct gtcagctatt tattataacc ccattaattt gcactccagt
    64981 attatcttca gccgaaaatc agtattttag gttgtttgaa ataaacttcc tagtttactc
    65041 ttttattttt atttttattt agcattagct ttagtaggat cttttaaacg agtttttatt
    65101 gcttatattt cttgtttagt ttagttggtt tcatatcact attatataat gcttttggaa
    65161 atgagcctag tataagtcaa aaacgtgttg aatagtgaaa gcaggagcat accaatatga
    65221 ctgatttttt actgtatttt aggtatgcaa aataatacta aatgaaacta aaatgaatac
    65281 ttcttgcttt tcttgagagt gaaaaagtac aataaaatga ttgtagtgat tgccacaaga
    65341 tactgactaa tagacatcgt atttgaagcc acaaatacag gtaaagaata aaaaggaaga
    65401 agttcaattg ctttgataaa caaatcatta ctagtattca tcatcgtatt taatatatta
    65461 gggataaaga gtagtaaagc tactaaaata ccaagccact tttcaatttg tataaataga
    65521 aaatgtaaga taatagaaaa taaaacagga ctaacaaaat tgtattgact acaatagcta
    65581 ctataaaatc taatcctaaa tcacctggaa tacccaattt acttactatg actagtaaca
    65641 caatgccatt caaagcataa ataatggaag ctgagatggc atatagaaaa ttagacaaga
    65701 cgtaaatcat ccgattcttc tgttgattat aaaacaaact taccgtattg tgggaaaaat
    65761 ctctactaat gactcgatta gcatgtataa cagccattaa cataccgagc atagcataaa
    65821 agtttgaaat atgcttaata ccaagcgatg tcccttaagt ctttagaata aagaatgtaa
    65881 gcaatatcgg cggtataaac gagataagca aactgagata tattacgcct gatgaatata
    65941 aatttcttat attttcctta agaaaattca atttatttaa tttcatgatt ataaccttcc
    66001 tttattttga acgatttagg taaatatctt taagcgtctc ttttttagtt tcaaaatcaa
    66061 ctactttaat agagttttcg ttaaaaaatt taaaaagctc actactttga atattcccag
    66121 acatagtaat tctcaatccc tcttcctgaa caatatcccc aaattcttgt ttggtaatga
    66181 aaatgtctct atctgtagct gatgaaaaag ctatctcaaa caagaaatta tgactatctt
    66241 ttcctacttt ttgaaatgtc aaaagcccgt tctccaagaa aagaactctc tcacaaattt
    66301 cttcaatgtc ttctaattta tgactcgata ttaaaattcc cacgttttca tttaaagcta
    66361 atttttttag aaccgctaaa actatttgtg atgattcaat atctaaacca ttagtcggtt
    66421 catctaaaat caatatatca ggttccgtaa cgagagttag aagcaaagct aatttttgtt
    66481 ttgtacccaa agaataggtc tttacttttt tattaataga ctgagtcaaa tctaactctt
    66541 ggatcaaact tctaaatctt tcttgattgt agtcaacacc atataaattt gacaaatatt
    66601 ttaaattctc taaacctgtt ttagataaaa ataattttgg ttcttcgatt aaatacccaa
    66661 cattatcact gcttataata ttacctgaag tcggttgatt attttgaaca agaattttca
    66721 tcaacgtact cttaccaact ccatttctcc ctactagacc aacaatttca cccttgttaa
    66781 gtgcaaaatt tatatctttg agaatgattg aatgaccata atgcttactt acatttttat
    66841 tcctacatta atattcatgg tttactcttt gattcttatt gagtttaaaa agttgcgcct
    66901 ctttttaaca atattatatc atatatctaa cttgatgcaa tatataaatg tcattttgta
    66961 aaattttatt aacaaaaaac tctctacaac aaaataatag agagttttct gcttattaat
    67021 ttttttcaaa atatctaaga catcgcttct ttgtttaatt tgataggctt tgatacctaa
    67081 gctccgactt tatcacttaa aaaataaaaa agacagctaa tctcttgcgc atcaagggat
    67141 ttcgccattc tttaatctcg tttaagtgtt gtatatggag ctttgcataa ttttttaaaa
    67201 ctaaacaact acattaagca cgaactgtga cgctggttcc atcttcctta taaagattga
    67261 taagcccctc tttaagagct cgaaccatgt ctcctgattg aacgggttgt gggactttaa
    67321 tagtcaatag ttccattgga tttggagcgc ggtcgatttt attgcctttg gcatcatgca
    67381 aatcttcaat ataggtttca aaatgacgga aacctggacc ataaaactca acttggtccc
    67441 cttcgttaat gacgtttcgt tgacgaatag ttgctgtttg tgccgcatca tcataagaaa
    67501 ccacttcagc gacaaacttg tactcaggga ttttacgacg agcaccaaac aactgctcat
    67561 tttcagatgg tgtaccatag taaaatcctg tagccagttc acgttgggca accttccaca
    67621 tctcgtccac caagtcttgt ttgatagctt caaacttttc aggactttca agataggcat
    67681 ccacaaccgc cttgtagcag ttggttactg ttaatacata gtgaatagac tccatacgtc
    67741 cttcgatttt tagactgtcc acaccatttt caatcatatc tggaatgtgg tcaatcatag
    67801 acatgtcaac ggctgacatt gaaaattctt ctggaatctc accctgcaaa ctcttacgtt
    67861 ctttcccaaa tggcatatcg taaaggtcgt atttccaacg gcatgactga gaacatccac
    67921 cacggttggc atcacgcata ctctagacgc aattctaatc ttttagactt tgcataataa
    67981 ctgttaaaca gttgaaaatt aacccagttt taacaagtag tcaaaatacc agataaagga
    68041 aaaaaagtct ttaaaatctt aaaaacgcat agtatcaggt attgaacaat cttgatatta
    68101 tgcgttttat tgtgggaaga tttacttcat tttctcttgg aattgagttt tctcctactt
    68161 caaaactaga tgatttgcta tttaaaatag cgttccttat gattttggca acctggatta
    68221 aagcgagaaa aacaaaaggg gcaacttaag ctttctttat attgcttata tgttagtagt
    68281 tttagacaaa caccacataa aataggctta tcctgtatca aagataaggg atacggctca
    68341 aaagggtgat tttctaatga atcatgacac cgataacaag catagtactt tttacaaaca
    68401 tagcattgta aagcaataat atccagcttg ctatggtaat gaatgcatct tgtttgctta
    68461 tccactaaga aaccctgtgc ctctatcatt tccttttcct ttcttaagct cgaactgtga
    68521 cgctggttcc atcttcctta taaagattga tgagtccttc ttttaatgca cgaaccatgt
    68581 ctccagcttg aacaggttga ggcaccttaa tagtcaatag ttccattgga tttggagcgc
    68641 ggtcgatttt attgcctttg gcatcatgca aatcttcaat ataggtttca aaatgacgga
    68701 aacctggacc ataaaactca acttggtccc cttcgttaat gacgtttcgt tgacgaatag
    68761 ttgctgtttg tgtcgcatca tcataagaaa ccacttcagc gacaaacttg tactcaggaa
    68821 ttttacgacg agcaccaaac aactgctcat tttcagatgg tgtaccatag taaaatcctg
    68881 tagccagttc acgttgggca accttccaca tctcgtccac taagttttgt ttgatggctt
    68941 caaacttttc agaactttca agataggcat ccacagccgc cttgtagcag ttggttactg
    69001 ttgatacgta gtgaatagac ttcatacgtc cttcgatttt tagactgtcc acaccatttt
    69061 caatcatatc tggaatgtgg tcaatcatag acatatcaac ggctgacatt gaaaattctt
    69121 ctagaatctc acccttcaaa ctcttacgtt ctttcccaaa tggcatatcg taaaggtcgt
    69181 atttccaacg gcatgactga gaacacccac cacggttggc atcacgcata ctcatgtggt
    69241 ttgaaagagt acaacgtcca gagtatgaaa tacacatagc tccatggaca aaggcttcaa
    69301 tttcaacatc tgtacgtttg cggatttcag ctaattcttt cattgaaacc tcacgtgcta
    69361 aaacgacacg agtcaagcct agctctttcc agaactcaag ggtttcatag ttagtggcac
    69421 tggcttgggt agaaaggtgg atttcaaggc ctggtgcttc agtcgctgca atcataatca
    69481 aggctgggtc agatacgata actgctgcaa tcccgatatc acgcagttta cgaaaccact
    69541 caccagcacc agcttcattt ccttcgtgca taaccatatt agccgctaca tagaccttgg
    69601 caccatactt ggccgcaaac tgcacgcctt cttccatctg ttcgaaagta aagtttcccg
    69661 cacggctacg aagaccatag gcctgaccac cgataaagac agcatctgct ccatactgaa
    69721 cagctacctt tagcttctct aaagtccctg caggtgataa aacctcagga cgttttaatg
    69781 tttttgtcat gatttctcct atttgcaata taaaagtttg acatttttcc ttctcatttt
    69841 atagtaaata aaggataaaa tcaagcctag acggattgtt ttgacaattc taatctttta
    69901 gactttgcat aataactatt aaacagtcga aaattacccc agttttaaca agtagtcaaa
    69961 aagtctaaaa aagtaaaaac cagtatccca agatactgac tcgtaaaaat atataaatta
    70021 gtccttagat gactactccc actctgttgc tcctataatg gaaaaggatt gatacagtct
    70081 agaatatcgc ttttttattt attattctga tataaaactg ttagaattga ttttttgttt
    70141 tatacccaaa tatgaataga gacgtagcta ataagttgaa taacatattt ggaaaaatga
    70201 gaaatagcaa tattactaga acttttagaa acaatcaata tttaaaaaga aaaaagctca
    70261 aagaatttat taaaccatgt tataatagat atagctataa ttttatttat aacaagagga
    70321 tagaaatgac cgaattagaa agaaaaaatc gaaaaattag ctaagaaata ttctgataac
    70381 ttaaacatca aagttcaaga gagagttcgt gaaatggcaa atgataataa gagccattat
    70441 ttgatataca gagttttagg tatttcattt gaagaaggag aaaatatcga tttgtatcaa
    70501 aataaaggtc gttttttata caaatatgct ggttcatttt tagaagaagc tgcagtacta
    70561 tcctttaacg aaaaatttgg tacagaaaat acttaaaaag ttaacattcc taattctgaa
    70621 aatacaaaac ctaagacttt tgaaattgat tgtttagtcg gagaaaaaca cgcatacgaa
    70681 ataaaatggt gggatgcaac tacagatgga gaccatataa ctaaagaaca cactagaata
    70741 aaagttattc ataacaaagg atatatacca attcggttaa tgttctacta tccaaataga
    70801 actcaagcta taaaaattca gcaaacttta gaaacattgt ataacggtat tggagggaaa
    70861 tattattatg gagattctgc ctgggaacat ttaagagcag tgaccggtat tgatttactt
    70921 agtattctaa cagatattgc aaataaaaaa acaggggtaa aatcaaaatg acagtattaa
    70981 aaggagataa cttagaaata ttaaaaacta ttgaatcctc aagtattgat ttaatctata
    71041 tggaccctcc tttctttaca cagaaaaccc aaaaattatc taataacaaa aatattatgt
    71101 attcattcga agatacgtgg acttcgattg aggattacaa agaatttttg tctgtaagat
    71161 tagaagaatg caaaagagtg ctaaaaaata gtggcagtat tttcgttcat tgtgataaaa
    71221 ttgcaaatca tcatattaga ttaattttag ataatatctt tggagcagat atgtttcaaa
    71281 gcgaaattat atggaactat aaacggtggt ctaattcaaa aaagggatta ttgaacaatc
    71341 atcaaaacat ttacttttat tcaaagtcaa aagattttaa atttaataca atttttacag
    71401 agtattcttc tactacaaat atcgaccaaa tactagtaga acgaaaacga aatggaaact
    71461 ctaaaactat atataaagtt gataataatg gtaactatat tctagcaaaa gagaaaaatg
    71521 gagttcccct ttcagatgtt tggaatatac catttcttaa tccaaaagct aaagaaagag
    71581 taggttatcc tacacaaaaa cctattctgt tattagaaca aattataaag attgctactg
    71641 ataaaaatga tatagtttta gacccgttct gtggaagtgg aactacttta gtagcctcca
    71701 agattttgaa tagaaattat atggggattg atttatctga ggaagctatc aatataactc
    71761 agcaacgtct ggaaaatgtt ataaaaacaa gttcaaattt attgaataaa ggaatcgaag
    71821 catatagaac caaaactgag gaagaggaaa acattcttaa attattacag gcaaaaattg
    71881 ttcaaagaaa taaaggaatt gatggttttt tacctaaaca ttttcaaaaa aaaccgatac
    71941 ctataaaaat tcaaaaaaat aatgaatgtc tgaatgagag tatctcttta ttacagaatg
    72001 ctataaactc caaaaaactt gattttggag tagttataaa aactcattca gataatttat
    72061 tatttgattt tgatacgatt cctgaaaata taatagtagt tgaccatttt gaacttacaa
    72121 tcgaaaaatg gttaagtaaa agtcaacagt tactatagtt tgcaaattat ttacagaaag
    72181 aacaaaaaat gctctgaaac actgatttca aggcattttt tgttagttta aaattactcc
    72241 cattcttctt ttccaaacgt acaatatatc caaaaccatt caaaatacta gattctattt
    72301 tttataatat cactaaatcc acctaattat aggacgtttt cagattttta gtcccgtccc
    72361 agtcccagta ccggagaaat attgttttaa tataatatct ctttttgtct tctaagctct
    72421 taaaagcaaa agaacaagta aagagtcaag acaaggataa aaagtccata ttagggcaaa
    72481 taaaaagctt taagacagat gacaaatcta agtcaaataa gaaagaccat agcaaaggtg
    72541 cagagagata aatattggcg gtcttcggac tgcctttatt tttttatcca tttttcaaat
    72601 caaatttatt cagactatat atgcacatat acacttaaat tcatataaaa acatggcttg
    72661 taaaaaatta ctttaatcac aataatcgca tttaaaattg tgatgtttgc aagctaaatt
    72721 acggacttca cttggaagtt ttcccttgta tcttttataa tagatagaaa atttgctggc
    72781 agatgaatat ccaacagatt ctgctatctc ttttataggt agttcagtgt ttaaaagaag
    72841 agtttcagct acattcattc tttttctttg agtgtactct gtaatgcttt gacaatattt
    72901 ttccttaaat aaatttttta atttagtacc actcatttta gatatttttt caagcgtgcc
    72961 ttgatttaca ttcgttgcaa aatgatcatc taagaatctt gctacatctt caagtgcttt
    73021 atcatcatca atttcaattt tatatttttt tctatttaag tatgtgtcaa ttactatact
    73081 tatccattca tttgcctttg ctttaaagaa aaaatcagcg gcaggagcgt ccatcttaca
    73141 atttaatatt tccattgcca ctctttctaa ggcctttgta agtattattt gattcggttg
    73201 aagcaaggtt gaataaaaag attctggatt aatgttaata gatgctaaat gtttttctat
    73261 tagctctttt ttaaaaccaa tggaaacagc aagataacaa caattctcgt gtaataaaaa
    73321 aacaaaatca tcttttatat tatcaaaatc aaaagtacat aaagagtttg cggtaatagt
    73381 ttgatacgga ttaaactttt ctccgtttgc actgacaatg taacttgaat aaattgaaac
    73441 atagtctgac atactataag tgctattttg aactacttcc tctttgatat aaaaatcatg
    73501 tatatcgata atgaagctgc ctccttcata aaaccaatat aggccttctg cataagttga
    73561 attctctttt ttccaacaaa atgtatgacc tgcacttgaa tacttctcat tgtttttaca
    73621 ttcatctact ttcatataat cttttacaaa atcataatat gacataacac actatccctt
    73681 ttagacaata ttccaattag ccttattaat tcaaaactat tgtattagta attataacag
    73741 atgtataata gaaaagcaat gatagatatt atcaattaag cgaatttata tctaaaaggg
    73801 atattaaaga aaggagatat gcttatgaag atttacaaaa aactatttgc ttatgtccaa
    73861 gataagaaat atcttggggt tttggccata attttttctg ctatatctgc tgtacttaca
    73921 gtatatggat attatttaat ctacaaattt ctagataagt taataattaa ttcaaactta
    73981 tccggtgcag agagtatagc attaaaatct gttattacac taacaagtgg agcgatattt
    74041 tattttgtct caggaatgtt ttcacatatc ttgggattta ggcttgaaac aaatttaaga
    74101 aaaaggggaa tcgatggtct ggaaaaagca agttttaggt tctttgactt aaatccatct
    74161 ggtcaaataa gaaagatcat agatgataat gcagcacaaa ctcatcaggt ggtagctcac
    74221 atgattccag atagctctca ggcaatagtc acacctatac ttgtccttgt acttggcttt
    74281 atagtaagta taagagttgg cataattttg cttgctctta ctataattgg tggcttaatt
    74341 ttaggggcaa tgatgggcga gcaagaattt atgaagatat accaagaatc cctatctaaa
    74401 ctaagtgctg aaactgttga gtacgtgaga ggaatgcaag ttgtaaaaat atttaaagca
    74461 aatgtagagt cttttaaaag cttttataag gcgataaaag attactcaaa gtatgcttat
    74521 gattattccc tatcttgtaa aaggccttat gttttgtatc aatggttatt ttttggactg
    74581 attgcaattt taattattcc tatagtttat tttatgacta gcttagctag cgcagaggtg
    74641 attttacttg agcttatcat gattttattt ttatcaggag ttctctttgt ttcattcatg
    74701 agaatgatgt ggtactccat gtatatttct caaggaaatt atgcagtaga tactttagag
    74761 gcgctttacg aagatatgca aaaagacaaa ttagtgcatg gtaatgtcaa taattttaaa
    74821 aactataata tagaatttga gaatgttagc tttgcttata atgataaagc tatcattgaa
    74881 aatttatcct ttaatttaga agaaggaaag tcctacgcac ttgtcggttc atctggatca
    74941 ggcaaatcaa cagtagcaaa acttatatca ggtttttaca atgttaataa aggaagcata
    75001 aagataggcg ggatagcaat aagtgaatat tctgacgaag ccttaattaa agccatttcc
    75061 tttgtttttc aagattcaaa attattcaag aagagcattt atgataatgt agctttagct
    75121 aataaagatg cgacgaaaga tgacgttatg agagccttaa aattagcagg atgcgattta
    75181 atattagaca aattcccaga aagagaaaat acaatcatag gctcaaaagg tgtttattta
    75241 tccggtggag aaaaacaaag aattgcaatt gctagagcaa ttttaaagga ttccaaaatt
    75301 attattatgg atgaagcatc agcatctatt gacccagata acgagtttga attgcaaaaa
    75361 gcttttaaaa atcttatgaa ggataaaaca gttatcatga ttgcacacag gctatctaca
    75421 attaaagacc ttgatgaaat tattgtcatg gatagtggaa aaattataga aagagggtct
    75481 gacaaagaat taatgtcaaa agatacaagg tataagagcc tgcaagagat gtttaacagt
    75541 gcgaatgaat ggagggtttc aaatgaaaga gttttataaa aaaagatttg ctcttacaga
    75601 tggaggagca agaaatttaa gtaaagcaac actggcttca tttttcgttt attgtataaa
    75661 catgcttcct gccatattac ttatgatttt tgctcaggaa gttttggaaa atatgggcaa
    75721 aagcaatggc ttttatatag tattctcagt tttgactttg atagcaatgt atattttgct
    75781 ttctatcgaa tacgataaat tatataacac aacctatcaa gaaagtgcag atttaagaat
    75841 aaggacagcg gagaatttat caaaattacc tctatcttac ttttctaaac atgacatttc
    75901 cgacatttca caaacaatca tggctgatat tgaaggcata gagcatgcaa tgagccactc
    75961 aataccaaag gtgggcggca tggtactgtt tttcccatta atatctgtaa tgatgctagc
    76021 gggcaatgtc aagatgggtt tagctgtaat tattccatct attttaagct ttatatttat
    76081 acctttatct aaaaaatatc aggttaatgg acagaataga tattatgatg tcttaagaaa
    76141 aaactcagaa agctttcaag aaaatatcga aatgcaaatg gagattaaag catataattt
    76201 atcgaaggat attaaagatg acttatataa aaaaatggaa gatagtgaga gaatacactt
    76261 aaaggcggaa gtaactacaa ttttaacttt gtctatatct tcaatattta gctttatatc
    76321 tcttgctgtt gtgatatttg tcggcgtaaa tctaattatt aataaagaga taaattctct
    76381 ctaccttata ggatatttac tagctgctat gaagataaaa gactctttag atgcatctaa
    76441 agagggcttg atggaaatat tttatttatc gcccaaaata gaaagattaa aagaaattca
    76501 aaatcaagat ttacaagaag gcgatgacta tagcttaaaa aaatttgata ttgatctaaa
    76561 agatgttgag tttgcctaca ataaagacgc aaaagtttta aatggtgtaa gttttaaagc
    76621 taagcaggga gaggtcactg ctttggtagg tgcaagtggc tgcggtaaaa caactatctt
    76681 gaaacttata tcaagacttt atgattatga caagggacaa atcttaatcg atggcaaaga
    76741 tataaaagaa atatcaacag aatctctttt tgataaggtc tctatagttt tccaagatgt
    76801 ggttctcttt aatcaaagcg ttatggaaaa tattagaatc ggtaagcaag atgcaagtga
    76861 cgaagaggtt aaaagagcag caaaacttgc aaattgcaca gattttatag aaaaaatgga
    76921 taaaggtttc gatacagtta ttggtgaaaa cggagctgag ctatcaggag gagaaagaca
    76981 aagattatca atagccagag ccttcttaaa agatgcgccg atattgatct tagatgagat
    77041 aacagcaagc cttgatgtta acaacgagaa aaagattcaa gagtctttaa ataatttagt
    77101 taaagataaa actgttgtaa tcatttcaca tagaatgaaa tccatagaaa atgcagacaa
    77161 gatagtagtt cttcaaaacg gaagagtaga aagcgaaggt aagcatgaag agcttttaca
    77221 aaaatcaaaa atttacaaaa atttaataga aaagacaaaa atggcagaag aatttattta
    77281 ttaggaggac tacaatggat aataaaaaat taaaagtaaa agatttagta agtatcggtg
    77341 tttttggcgt aatttatttt gccttcatgt ttggagttgg tatgatgggc ttgattccaa
    77401 tattgttctt aatatacccg acagtattag ccatagttgc aggaactgtt gttatgttat
    77461 ttatggctaa ggttcaaaag ccatgggcac tatttatatt tggtatgata tcaccacttg
    77521 tgatgtttgc agctggtcat acctacgtag ttgtggtttt atcacttata gtaatgataa
    77581 tagcagaatt aattagaaag attggtaatt ataattcatt taaatacaat atgctttctt
    77641 atgcaatctt cagcacatgg atatgtagct ctttaatgca aatgctttta gcaaaagaaa
    77701 aatatatgga gtggtctttg atgacgatgg gaaaagatta tgttgatgta ttagaaaagt
    77761 taataactta tcctcacatg gctttaatag ccttaggtgc tttcttagga ggaattcttg
    77821 gagcatatat aggcaaggct ctattgaaaa aacacttttc aaatggatta tattgtgtgg
    77881 gatactttac tccttgccta attttatggt gttatctgaa ttaaacccta tagttaagat
    77941 gtttttgagt atacctattg ttattagaat gtttatttta ccatttatgg cagcaagctt
    78001 tatgataaag acctcggatg taggcgcaat aatttcatcg atggataagc ttaagatttc
    78061 aaagaatgta tccataccta ttgcggttat gtttagattc ttcccatctt ttaaggagga
    78121 gaagaaaaac atcaaaatgg ctatgagagt aagagggata aattttaaaa acccagtcaa
    78181 atatcttgaa tatgtttctg tgccactact cattatatca tctaatatat cagatgacat
    78241 tgcaaaagcg gcagaaacaa aggcaataga aaatccaatt gccaagacca gatacattcg
    78301 cgtaaagata cagctaattg attttgttta tgttttagcg gttgctggac ttattgtggg
    78361 aggcttaata tggttgaaat aaaaaattta agtcttgatt atggtgaaga gcatatatta
    78421 gatgatatat cactatccat agccgaggga gagtgcgtgc tatttacagg aaaaagtgga
    78481 agtggtaagt catctttaat aaattcaatc aatggactag ctgtaaggta tgataacgca
    78541 aagacaaagg gcgaaataat tattgatggt aagaatataa aaaatttgga actttatcaa
    78601 atctcaatgc ttgtttcaac tgtttttcaa aatcctaaga catatttttt taatgtcaat
    78661 acgacattag aattattatt ttatttggaa aatatcggtc ttgcaagaga agagatggac
    78721 aggcgtttga aggatatact tgagatattc ccgataaaaa atcttttgaa cagaaatata
    78781 tttaatctat ccggcggtga aaaacaaatt ctttgcattg cagcttctta tatagcaggt
    78841 acaaagatta tagttatgga tgagtcttca tcgaatttag atattaaaag cataagtgtt
    78901 ttggcaaaga tgctaaagat attaaaagag aaaggcataa gcataattgt tgcagagcat
    78961 agaatttatt atttgatgga catagttgac cgtgtatttt taatagataa aggaaagctt
    79021 aaaaaaactt atactagaag tgaattttta aagctagata aaaatgaatt aaatgcttta
    79081 agtttaagag ataaagaatt aagtaaatta aaagttcctt atttaaaaga aggtggagag
    79141 tatcagataa aaaatcttag ctacaaattt actgatgatg agtgtttaag cttaaaagat
    79201 atttcgttca agcttgggaa aatttatggc ataataggat ccaacggacg aggaaaatca
    79261 acgcttttaa gatgtttaat aggtcttgag aaaaaatcaa aagaagaaat ttattttaag
    79321 ggagagaagc tatctaaaaa agaaagactc aaaaactctt cacttgttat gcaagatgta
    79381 aatcatcaat tattcacaga tgaagtattc aacgagctta gattaggagt aaagaatttt
    79441 gatgaagaaa aggcgaaaat cattttaaaa gatttaggcc tggacgaatt tattgaaagg
    79501 catccgatga gtttatcagg agggcaaaag caaaggcttg caatagcatc tgttatgtgc
    79561 aagacttctc catttatctt ttttgacgaa ccttcaagtg gtatagatta ttccaatatg
    79621 ataaaaatat ctgaactgat taataagtat aaaaccatgg ataaaataat ttttattgtt
    79681 tcccatgata tagaattttt aaatgaagtg gcagatgaaa tttttgaatt gtaaaataga
    79741 gtctgttaaa catgtctata gaactggtaa attgtctaaa aatttaaaag atactaacac
    79801 atattgatat ttattagaaa attaacttca ggatttttac agtatttata aactttataa
    79861 tatgtattta tagtattaat aatttccata tctttaggga aattatttat ttacttacca
    79921 taattaaaga gatgagagat aaatatcggc agtcttcgga ctgcctttat ttttttactt
    79981 aatttaatgc agtaaatcat acgattgaaa ggaatctgcg ttatatgcta taattaggta
    80041 gttaatctat acatttagaa aggtaaaata tagaattgga gaatgatatg ggattttcat
    80101 ataataaatt gtaacc
//
LOCUS       DAVBIC010000002        79090 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.002, whole genome shotgun sequence.
ACCESSION   DAVBIC010000002 DAVBIC010000000
VERSION     DAVBIC010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 79090)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 79090)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..79090
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.002"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            complement(48..1937)
                     /locus_tag="VQ664_000081"
     CDS             complement(48..1937)
                     /locus_tag="VQ664_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HET2788332.1"
                     /translation="MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKVQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGAEKLFFHTGKLFREGTIEKSNLDYTIRLDNLPAKRGVELHAYWPRTDFASARDQG
                     LKGNRLEEFNKIEDSIVREKDQSKQLVTWVLPSILSISLLLSVCFYFIYRRKTTPSVK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVIDRG
                     NVSIISEGDAVGLRLVKEDGLSSFEKDCLNLAFSGKKEETLSNLFADYKVSDSLYRRA
                     KVSDEKRIQARGLQLKSSFEEVLNQMQEGVRKRVSFWGLPDYYRPLTGGEKALQVGMG
                     ALTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDQAELESIVVWNRLLVYATLFGYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSLFYHSSAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            2075..3640
                     /locus_tag="VQ664_000082"
     CDS             2075..3640
                     /locus_tag="VQ664_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HET2788333.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKKPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEIAFSSSYYTSEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYD
                     LIAQIPGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMIQVEPGF
                     KTGEEDTAIAIGLRKNDNRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTIIGLIIGLAIGVFRTAPLSENKAIYG
                     LQKLVGWVLNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMCKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            3640..4404
                     /locus_tag="VQ664_000083"
     CDS             3640..4404
                     /locus_tag="VQ664_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET2788334.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEEIAKENLEKVGMGERYWQARPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYLILNENQRAN"
     gene            complement(4603..4818)
                     /locus_tag="VQ664_000084"
     CDS             complement(4603..4818)
                     /locus_tag="VQ664_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2788335.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNHEKFED"
     gene            complement(5689..6939)
                     /gene="ilvA"
                     /locus_tag="VQ664_000085"
     CDS             complement(5689..6939)
                     /gene="ilvA"
                     /locus_tag="VQ664_000085"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HET2788336.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIQTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
     gene            complement(6989..7345)
                     /locus_tag="VQ664_000086"
     CDS             complement(6989..7345)
                     /locus_tag="VQ664_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HET2788337.1"
                     /translation="MNITNLFSIKTGCDETDRQLQKLFFQLDLQLGELTDQLRKLDSN
                     FVPRSQFVDTLDLNDVEYKEILNYFIFHRNDSEESLVEWLYDWISTNRYELPKEFSIR
                     MAHKYHESVTEVFGDE"
     gene            complement(7583..7819)
                     /locus_tag="VQ664_000087"
     CDS             complement(7583..7819)
                     /locus_tag="VQ664_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2788338.1"
                     /translation="MLADQNKADWSYDENAVINIYDDANFEDGRLHMTFEQFFKLAQI
                     AREEGLEIHSPFERAGATKSARYIAKWILRNKKH"
     gene            complement(7926..8948)
                     /gene="ilvC"
                     /locus_tag="VQ664_000088"
     CDS             complement(7926..8948)
                     /gene="ilvC"
                     /locus_tag="VQ664_000088"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HET2788339.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVVEATKLADVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            complement(9014..9490)
                     /gene="ilvN"
                     /locus_tag="VQ664_000089"
     CDS             complement(9014..9490)
                     /gene="ilvN"
                     /locus_tag="VQ664_000089"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HET2788340.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            complement(9483..11183)
                     /locus_tag="VQ664_000090"
     CDS             complement(9483..11183)
                     /locus_tag="VQ664_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HET2788341.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVQFHA
                     "
     gene            complement(11384..13051)
                     /locus_tag="VQ664_000091"
     CDS             complement(11384..13051)
                     /locus_tag="VQ664_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HET2788342.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDTVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
     gene            complement(13054..13419)
                     /locus_tag="VQ664_000092"
     CDS             complement(13054..13419)
                     /locus_tag="VQ664_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HET2788343.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            complement(13576..13764)
                     /locus_tag="VQ664_000093"
     CDS             complement(13576..13764)
                     /locus_tag="VQ664_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HET2788344.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            complement(13880..14056)
                     /locus_tag="VQ664_000094"
     CDS             complement(13880..14056)
                     /locus_tag="VQ664_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HET2788345.1"
                     /translation="MDSDIVVRKSIDELWDLDLTAIPLAAVRDDFYTHNFNSGVLLIN
                     DGMWRAENVTQDLI"
     gene            complement(14167..14316)
                     /locus_tag="VQ664_000095"
     CDS             complement(14167..14316)
                     /locus_tag="VQ664_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HET2788346.1"
                     /translation="MDKVETTIKSLCVHHYNLKFYVFNDDLPREWFQLMEKRLETLNS
                     EIVNV"
     gene            complement(14628..16172)
                     /locus_tag="VQ664_000096"
     CDS             complement(14628..16172)
                     /locus_tag="VQ664_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HET2788347.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLEIFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVINAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMNPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            16385..16687
                     /gene="gatC"
                     /locus_tag="VQ664_000097"
     CDS             16385..16687
                     /gene="gatC"
                     /locus_tag="VQ664_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HET2788348.1"
                     /translation="MKITQEEVTHVANLSKLRFSEEETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGTDRDRLFKNVPEQDNYYIKVPAILDDGGDA"
     gene            16687..18153
                     /gene="gatA"
                     /locus_tag="VQ664_000098"
     CDS             16687..18153
                     /gene="gatA"
                     /locus_tag="VQ664_000098"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HET2788349.1"
                     /translation="MTFNNKTIEELHNLLVSKEISATELTQATLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDANNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAIASEDTKDSTSAPVRIADFTSKIGQDIKGMKIALPKEYLGEGIDPEVKE
                     TILNAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN"
     gene            18153..19595
                     /gene="gatB"
                     /locus_tag="VQ664_000099"
     CDS             18153..19595
                     /gene="gatB"
                     /locus_tag="VQ664_000099"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HET2788350.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDLHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVELEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEVQRQAEILRSGGQIRQETRRYDEANKATILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSDFFEKAVA
                     LGGDAKQVSNWLQGEVAQFLNAEGKTLEQIELTPENLVEMIAIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            19724..20284
                     /gene="efp"
                     /locus_tag="VQ664_000100"
     CDS             19724..20284
                     /gene="efp"
                     /locus_tag="VQ664_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HET2788351.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            20306..20695
                     /locus_tag="VQ664_000101"
     CDS             20306..20695
                     /locus_tag="VQ664_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HET2788352.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGVYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            20688..21110
                     /gene="nusB"
                     /locus_tag="VQ664_000102"
     CDS             20688..21110
                     /gene="nusB"
                     /locus_tag="VQ664_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HET2788353.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTNVETACRFAYTHDREDT
                     DVQLPAFLIDLVSGVQAKKEELDKQITQHLKVGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(21159..21536)
                     /locus_tag="VQ664_000103"
     CDS             complement(21159..21536)
                     /locus_tag="VQ664_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2788354.1"
                     /translation="MVLSNGQPTFLSTILSFVLLVIIGPVFEETLDRGYFMNTFFPKS
                     KYYLDVILSGLIFGISHLILSHRDPISLLYYSLIGFFFALVYRSTDNLRLTILCHSFF
                     NFLNHAKPIWIFVYNYIYYHFFR"
     gene            complement(21877..22062)
                     /gene="briC"
                     /locus_tag="VQ664_000104"
     CDS             complement(21877..22062)
                     /gene="briC"
                     /locus_tag="VQ664_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HET2788355.1"
                     /translation="MTGTETFTVLSTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRTG"
     gene            complement(22221..22988)
                     /locus_tag="VQ664_000105"
     CDS             complement(22221..22988)
                     /locus_tag="VQ664_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HET2788356.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEVGLSS
                     KELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY"
     gene            complement(22985..23851)
                     /locus_tag="VQ664_000106"
     CDS             complement(22985..23851)
                     /locus_tag="VQ664_000106"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HET2788357.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(23888..25255)
                     /gene="accC"
                     /locus_tag="VQ664_000107"
     CDS             complement(23888..25255)
                     /gene="accC"
                     /locus_tag="VQ664_000107"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HET2788358.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASSNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(25267..25689)
                     /gene="fabZ"
                     /locus_tag="VQ664_000108"
     CDS             complement(25267..25689)
                     /gene="fabZ"
                     /locus_tag="VQ664_000108"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HET2788359.1"
                     /translation="MIDIQGIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGTLTFAIGN"
     gene            complement(25686..26171)
                     /locus_tag="VQ664_000109"
     CDS             complement(25686..26171)
                     /locus_tag="VQ664_000109"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HET2788360.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPSPVAPTSAPAETVAEEVPAPAEASVASEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(26174..27409)
                     /gene="fabF"
                     /locus_tag="VQ664_000110"
     CDS             complement(26174..27409)
                     /gene="fabF"
                     /locus_tag="VQ664_000110"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HET2788361.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(27431..28162)
                     /gene="fabG"
                     /locus_tag="VQ664_000111"
     CDS             complement(27431..28162)
                     /gene="fabG"
                     /locus_tag="VQ664_000111"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HET2788362.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVIAIDGGLSM"
     gene            complement(28196..29116)
                     /gene="fabD"
                     /locus_tag="VQ664_000112"
     CDS             complement(28196..29116)
                     /gene="fabD"
                     /locus_tag="VQ664_000112"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HET2788363.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTAHLAHVEDQASLVALLEK"
     gene            complement(29109..30083)
                     /gene="fabK"
                     /locus_tag="VQ664_000113"
     CDS             complement(29109..30083)
                     /gene="fabK"
                     /locus_tag="VQ664_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HET2788364.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     ISIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVE
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWAGVVRND"
     gene            complement(30202..30426)
                     /locus_tag="VQ664_000114"
     CDS             complement(30202..30426)
                     /locus_tag="VQ664_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HET2788365.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            complement(30486..31460)
                     /locus_tag="VQ664_000115"
     CDS             complement(30486..31460)
                     /locus_tag="VQ664_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HET2788366.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGEELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANNRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(31460..31894)
                     /locus_tag="VQ664_000116"
     CDS             complement(31460..31894)
                     /locus_tag="VQ664_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HET2788367.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            complement(31988..32773)
                     /locus_tag="VQ664_000117"
     CDS             complement(31988..32773)
                     /locus_tag="VQ664_000117"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HET2788368.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            33098..34462
                     /locus_tag="VQ664_000118"
     CDS             33098..34462
                     /locus_tag="VQ664_000118"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HET2788369.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREVGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKEEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGE
                     SKED"
     gene            34465..34836
                     /locus_tag="VQ664_000119"
     CDS             34465..34836
                     /locus_tag="VQ664_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HET2788370.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGRKISRHFEVFTDKGKFLFASKDSGAILKIAREKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            35050..36324
                     /gene="serS"
                     /locus_tag="VQ664_000120"
     CDS             35050..36324
                     /gene="serS"
                     /locus_tag="VQ664_000120"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HET2788371.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILVK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGTDEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLTNYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSAAKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEALRPYMGGAEVIKP"
     gene            complement(36349..37248)
                     /locus_tag="VQ664_000121"
     CDS             complement(36349..37248)
                     /locus_tag="VQ664_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HET2788372.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACSGRRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPTWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLAE
                     TIICLTILFFVLGAYLIWLRKKV"
     gene            complement(37358..37906)
                     /locus_tag="VQ664_000122"
     CDS             complement(37358..37906)
                     /locus_tag="VQ664_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HET2788373.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            complement(38124..39446)
                     /locus_tag="VQ664_000123"
     CDS             complement(38124..39446)
                     /locus_tag="VQ664_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HET2788374.1"
                     /translation="MLELLKSIDAFAWGPPLLILLVGTGIYLTMRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSITESIQNTTTISPAITALVLSVFVAIAVFGGLKSISKVSTTVVPFMALIYI
                     LGTLTVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALT
                     QSAFSTVFSHFGPALLTIFLVLFAFTTILGWNYYGERCFEFLFGARFIWLYRVFFVLM
                     VLLGGFIELDMVWIIADIVNALMALPNLIALLVLSPVVIAETKKYFDK"
     regulatory      complement(39537..39625)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            complement(39789..42125)
                     /locus_tag="VQ664_000124"
     CDS             complement(39789..42125)
                     /locus_tag="VQ664_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HET2788375.1"
                     /translation="MNKKILETLEFDKVKALFDPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLASREL
                     QSFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRDVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVHFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKPV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(42229..42777)
                     /locus_tag="VQ664_000125"
     CDS             complement(42229..42777)
                     /locus_tag="VQ664_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HET2788376.1"
                     /translation="MISFLLLLVLVWGFYIGYRRGLLLQVYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIFYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPITTSWLKQIWVTNLIG"
     gene            complement(42774..43076)
                     /gene="zapA"
                     /locus_tag="VQ664_000126"
     CDS             complement(42774..43076)
                     /gene="zapA"
                     /locus_tag="VQ664_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HET2788377.1"
                     /translation="MANLNRFKFTFGKKSLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            43163..44044
                     /locus_tag="VQ664_000127"
     CDS             43163..44044
                     /locus_tag="VQ664_000127"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HET2788378.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQLVEENRGQNLPLIGTDEVGNGSYFGGLAVVAAFV
                     TSDQHDFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQEANRFSNPISLEEKAEG
                     KYLSVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLSFC
                     AKLHFKNTEKAKKRLER"
     gene            44048..44662
                     /gene="lepB"
                     /locus_tag="VQ664_000128"
     CDS             44048..44662
                     /gene="lepB"
                     /locus_tag="VQ664_000128"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HET2788379.1"
                     /translation="MNSFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRFWPITRIGTF"
     gene            44941..47307
                     /locus_tag="VQ664_000129"
     CDS             44941..47307
                     /locus_tag="VQ664_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HET2788380.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGLSAKNREAFVSTLRLNYGTEMVLSKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLVRILEKGKQKSHDLETIQKHITTIEEELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDFRKKSNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLANQL
                     FSNISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTHLEKIYRQSKESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGAALRNGIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKGDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDSIPAMIGITDTDLKEIFGK"
     gene            complement(47355..48638)
                     /locus_tag="VQ664_000130"
     CDS             complement(47355..48638)
                     /locus_tag="VQ664_000130"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HET2788381.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDKKFGEESLYQDVMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVIAAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     EDGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     AAAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQNLLSADMLKHDITIKKAVELITSTATVK"
     gene            complement(48832..49191)
                     /locus_tag="VQ664_000131"
     CDS             complement(48832..49191)
                     /locus_tag="VQ664_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET2788382.1"
                     /translation="MDSPKSLASYRVIGISDRVLEILKEYLLLEEGDYIFTNNGSPLM
                     ITCFNYFLKNRFRKSEIKKDDFVLTAHVFRYSHISLLAELEVPITAIMDRVDYTNETK
                     ILSVYTHVTEKMKSNIT"
     gene            complement(49490..50119)
                     /locus_tag="VQ664_000132"
     CDS             complement(49490..50119)
                     /locus_tag="VQ664_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HET2788383.1"
                     /translation="MVLSKYYGVADGMNVEGRGSANFIKDNVLITAAHNYYRHDYGKE
                     ADDIYVLPTVSPSQEPFGKIKVKEVRYLKEFRNLNSKDAREYDLALLILEEPIGAKLG
                     TLGLPTSQKNLTGITVTITGYPSYNFKVHQMYTDKKQVLSDDGMFLDYQVDTLEGSSG
                     STVYDASHRVVGVHTLGDGANQINSAVKLNERNLPFIYSVLKGYSLEGW"
     gene            complement(50164..50403)
                     /locus_tag="VQ664_000133"
     CDS             complement(50164..50403)
                     /locus_tag="VQ664_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2788384.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LEKGPGSNDSSLSEISPTYGSYYQKQSEVLSVMMI"
     gene            complement(50553..50819)
                     /locus_tag="VQ664_000134"
                     /pseudo
     CDS             complement(50553..50819)
                     /locus_tag="VQ664_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060522.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            complement(50844..51152)
                     /locus_tag="VQ664_000135"
     CDS             complement(50844..51152)
                     /locus_tag="VQ664_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HET2788385.1"
                     /translation="MDWDFADTCWEKEPRKYQYVAANYLKAMQSYLKETDLPKLEQLV
                     VTKSWWDTVDILDRVVGSLVYEHPELEEIILILFENLFKPRQLYLQPQNSVLRLQIAS
                     "
     gene            complement(51077..51319)
                     /locus_tag="VQ664_000136"
     CDS             complement(51077..51319)
                     /locus_tag="VQ664_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HET2788386.1"
                     /translation="MSLADLLEELEAAKDSKKARPMEAYMRHQFSFLGIAVPERNKLY
                     KNIYQKRKKQRLSIGILQTLAGKRSLENTNMWLLTI"
     gene            complement(51320..51952)
                     /locus_tag="VQ664_000137"
     CDS             complement(51320..51952)
                     /locus_tag="VQ664_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2788387.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF"
     gene            complement(51966..52961)
                     /locus_tag="VQ664_000138"
     CDS             complement(51966..52961)
                     /locus_tag="VQ664_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET2788388.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLYDVEKTEK
                     FVFLLLVFSMSMTCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVVDPDLDASFKS
                     LSGKLNLLTEALQKAENHSLDQEEEIIEKERKRIARDLHDTVSQELFAAHIILSGISQ
                     QALKLDREKMQTQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFRLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            complement(52958..53656)
                     /locus_tag="VQ664_000139"
     CDS             complement(52958..53656)
                     /locus_tag="VQ664_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HET2788389.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAATILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            complement(53734..54744)
                     /locus_tag="VQ664_000140"
     CDS             complement(53734..54744)
                     /locus_tag="VQ664_000140"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HET2788390.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAALKNPTDDS
                     FSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSKQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKAVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEAKDQMK
                     KA"
     gene            complement(54728..55735)
                     /locus_tag="VQ664_000141"
     CDS             complement(54728..55735)
                     /locus_tag="VQ664_000141"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HET2788391.1"
                     /translation="MIAVKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSY
                     RIYSDMFDFAVDLTPNPDYSLIQETIALMGDFLAVRGQNLRSFSLEICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYDVSVDQELLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKVAAWLEEENLATVLERDWGFSISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLSSSKETVVSLVEALEQGKSEKIIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDAQSTKTLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            complement(55722..56675)
                     /gene="mvaD"
                     /locus_tag="VQ664_000142"
     CDS             complement(55722..56675)
                     /gene="mvaD"
                     /locus_tag="VQ664_000142"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HET2788392.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVIADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YSVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEHLSEIFGQRYRLIVSKTKDLSQDDCC"
     gene            complement(56657..57535)
                     /gene="mvk"
                     /locus_tag="VQ664_000143"
     CDS             complement(56657..57535)
                     /gene="mvk"
                     /locus_tag="VQ664_000143"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HET2788393.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVP
                     AESPWRLYEEDTLSMAVYASLEYLDITEACIRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFLVETTLSHGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            complement(57657..57986)
                     /locus_tag="VQ664_000144"
     CDS             complement(57657..57986)
                     /locus_tag="VQ664_000144"
                     /inference="COORDINATES: protein motif:HMM:NF024736.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2788394.1"
                     /translation="MTRKAYDTDLNDQEWAKIEPYFSKHRTYKWPKRVLVNETLYVTK
                     TGCQWRMIPHDFPLYLTVWSFFRRSMTTGWFQVNGRWYYAYSSGALAVNTTVDGYSVN
                     YNGEWVQ"
     gene            58648..58984
                     /locus_tag="VQ664_000145"
                     /pseudo
     CDS             58648..58984
                     /locus_tag="VQ664_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811282.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic-modifying protein"
     gene            58884..59471
                     /locus_tag="VQ664_000146"
     CDS             58884..59471
                     /locus_tag="VQ664_000146"
                     /inference="COORDINATES: protein motif:HMM:NF017000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2788395.1"
                     /translation="MTILLKLSSTIVYGEIYHYFLQRDTAKESILDYSFAHGYCEIAY
                     ALFAYSKVLEPSMFYNDLHTFHAELKKLLEKVTSNTENLGNLQLSWCEGISGIILYLC
                     MYDCDGNKDIISKYQEFVFNHHLKMMTGYCHGITSLLQTTVYNQNKLLMKKIQQVILA
                     CSERDDHGLLMFQGDSGKADLFDFGIGSRGYIGVY"
     gene            59514..60746
                     /locus_tag="VQ664_000147"
     CDS             59514..60746
                     /locus_tag="VQ664_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET2788396.1"
                     /translation="MKLFWTNNIYRQLLLNSCFSSFGDSIFYLAIINYVAQYNFAPLA
                     ILLISISEMVPLLSQLFLGILGDFQENRVKHALCIAKIKILLYAILTVFLVLSPFSLV
                     SVIMIVIINLISDTLSYLSAYMMNALYISVIKDDLHDAMGFRQSLMRVVHIVANLAGA
                     FLINVISIQTISLINTLTFVIAFLGLYVIRHTLYEVEKRIEMSHTALSFKKYFQHLKQ
                     SLAVLLRLKDTVILLFLTTSMIAILDVSPRLIALRFIQQTLAQLSIGQLFALLSIIMS
                     CGAILGNMTSSNLFKNIRFTHLLVFCEISLLALITSILCQAYIVIFVTSFISSTIIGI
                     LSPRLQAAVFAHIPSDKMGTVGSALSTVDILAPSLLSLLALSIASGVSVQLALIFLYL
                     ILIALIFCQWLVKFNTHN"
     gene            complement(60864..61820)
                     /gene="cbpC"
                     /locus_tag="VQ664_000148"
     CDS             complement(60864..61820)
                     /gene="cbpC"
                     /locus_tag="VQ664_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HET2788397.1"
                     /translation="MKLLKKMMQVLLAVFFFGLLATNTVFANTTGGRFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIPGTGYRDDLFDNRPVFEIGLQEKW
                     YYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYE
                     DGNWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLRSSGAMA
                     TGWYQEGTTWYYLDQPNGDMKTGWQNLGNKWYYLRSSGAMATGWYQDGSTWYYLNAGN
                     GDMKTGWFQVNGNWYYAYSSGALAVNTTVDGYSVNYNGEWVR"
     gene            complement(61918..62607)
                     /locus_tag="VQ664_000149"
     CDS             complement(61918..62607)
                     /locus_tag="VQ664_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2788398.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVSYIY
                     KPVFIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTMQE"
     gene            complement(62619..64043)
                     /gene="gndA"
                     /locus_tag="VQ664_000150"
     CDS             complement(62619..64043)
                     /gene="gndA"
                     /locus_tag="VQ664_000150"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HET2788399.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVSDVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSRKDDEDQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVHASKVLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            complement(64119..65513)
                     /gene="mapZ"
                     /locus_tag="VQ664_000151"
     CDS             complement(64119..65513)
                     /gene="mapZ"
                     /locus_tag="VQ664_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HET2788400.1"
                     /translation="MSKKRRNRHKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEEFVETQSLDDLIQEMREAVEKSEASSEEV
                     PSSEDILLPLPLDDEEQGLDPLLLDDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTNSN
                     KTALKNSQFDKLSQLKTLLDKLEGSREHTLAKSKYDSLVTQIKAIQDVNAQFEKPAIV
                     DGVLDTNAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSSSQTSSSSSS
                     QASSNTTSEPKPSSSNETRSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAW
                     DFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGY
                     FVGNGAGHADDLDY"
     gene            complement(65526..66683)
                     /locus_tag="VQ664_000152"
     CDS             complement(65526..66683)
                     /locus_tag="VQ664_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HET2788401.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREVRELGYDCQVENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARLPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFEEWNWISDRLIQEVRTEAAKKVERKLELDIMGCDIDARMVEIAKANA
                     QAAGVAGDITFKQMRVQDLRSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            complement(66768..67148)
                     /gene="rnpB"
                     /locus_tag="VQ664_000153"
     ncRNA           complement(66768..67148)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VQ664_000153"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            complement(67169..67498)
                     /gene="gpsB"
                     /locus_tag="VQ664_000154"
     CDS             complement(67169..67498)
                     /gene="gpsB"
                     /locus_tag="VQ664_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HET2788402.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            complement(67568..68095)
                     /locus_tag="VQ664_000155"
     CDS             complement(67568..68095)
                     /locus_tag="VQ664_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HET2788403.1"
                     /translation="MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGSLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDQLNELAENFSEN"
     gene            68161..68757
                     /gene="recU"
                     /locus_tag="VQ664_000156"
     CDS             68161..68757
                     /gene="recU"
                     /locus_tag="VQ664_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HET2788404.1"
                     /translation="MINYPHKVSSQKRQTSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKGQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            68754..70913
                     /locus_tag="VQ664_000157"
     CDS             68754..70913
                     /locus_tag="VQ664_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 1A"
                     /protein_id="HET2788405.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVAYPDDELQVASTIV
                     DVSNGKVIAQLGARHQSSNVSFGINQAVETNRDWGSTMKPITDYAPALEYGIYDSTAT
                     IVHDEPYNYPGTNTPVYNWDRGYFGNITLQYALQQSRNVPAVETLNKVGLNRAKTFLN
                     GLGIDYPSIHYSNAISSNTTESDKKYGASSEKMAAAYAAFANGGTYYKPMYIHKVVFS
                     DGSEKEFSNVGTRAMKETTAYMMTDMMKTVLTYGTGRNAYLAWLPQAGKTGTSNYTDE
                     EIENHIKTSQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGNGLTVAAKVYRSMMTY
                     LSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWSSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQPAQP"
     gene            complement(71080..76383)
                     /locus_tag="VQ664_000158"
     CDS             complement(71080..76383)
                     /locus_tag="VQ664_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HET2788406.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPADLATALATANENDGRDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPAAAKPETPKTVTPEWQTVEKKEQQGTVTIREEKGVRYNQLFSTAQNDNAG
                     KPALFEKKGLTVDANGNATVDLTFKEDSEKGKSRFGVFLKFKDTNNNVFVGYDKDGWF
                     WEYKTPGNSTWYKGNRVVAPEPGSVNRLSITLKSDGQLNASNNDVNLFDTVTLPGAVN
                     DNLKNEKKILLKAGTYGNDRTVVSVKTDNQEGVKADDTPAQKETGPVVDDSKVTYDTI
                     QSKVLKAVIDQAFPRVKEYSLNGHTLPGQVQQFNQVFINNHRITPEVTYKKINETTAE
                     YLMKLRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLLSSISF
                     LGNALVSVSSDQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVSTDKLA
                     AGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFPEYTKE
                     LPSAKVVITEDANADKKVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFGSQAQN
                     PFLMTLDGIKKINLHTDGLGQGVFLKGYGSEGHDSGHLNYADIGKRIGGVEDFKTLIE
                     KAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDAAYDLA
                     HGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRFAIEWG
                     HGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAANYPLL
                     GGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDNGSTYK
                     WTPEMRVELVDADNNKVVVTRKSNNVNSPQYRERTVTLNGRVIQDGSAYLTPWNWDAN
                     GKKLSTDKEKMYYFNTQAGATTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVKDGKIT
                     LDLLANQPYVLYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEIVKSQG
                     ANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKASITVNTGEKEVTTYT
                     NKSLALNYVKAYAHNTRRNNATVNDTSYFQNMYAFFTTGSDVSNVTLTLSREAGDQAT
                     YFDEIRTFENNSSMYGDKHDTGQGTFKQDFENVAQGIFPFVVGGVEGVEDNRTHLSEK
                     HDPYTQRGWNGKKVDDVIEGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYRVTFEY
                     EAGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWTDSKKAKKATFLVTGAETGD
                     TWVGIYSTGNASNTRGDSGGNANFRGYNDFMMDNLQIEEITLTGKMLTENALKNYLPT
                     VAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIEALKNALVQKKTALVADD
                     FASLTAPAQAQEGLANAFDGNLSSLWHTSWNGGDVGKPATMVLKEPTEITGLRYVPRG
                     SGSNGNLRDVKLVVTDESGKEHTFTATDWPDNNKPKDIDFGKTIKAKKIVLTGTKTYG
                     DGGDKYQSAAELIFTRPQVAETPLDLSGYEAALAKAQKLTDKDNQEEVASVQASMKYA
                     TDNHLLTERMVEYFADYLNQLKDSATKPDAPTVEKPEFKLSSLVSDQGKTPDYKQEIA
                     RPETPEQILPATGESQSDTALFLASVSLALSALFVVKTKKD"
     gene            complement(76684..78666)
                     /locus_tag="VQ664_000159"
     CDS             complement(76684..78666)
                     /locus_tag="VQ664_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2788407.1"
                     /translation="MKSSKLLALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDA
                     KWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGEIKDFSQVG
                     IKALDDQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHVDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSMKDNIVYTQQGSITYLVGTNIDRQSYKYTSKTSDEQKASTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGQTGASKILRNIFVPPTFVQADGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVTFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVIIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDEATDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPVLYKYLELQ
                     DKAVTVDEYQKAQEKWMKEKEESNKKAQEDLAKHVK"
BASE COUNT        23012 a        18008 c        14623 g        23447 t
ORIGIN      
        1 ttctatcttc cattatatca tactttttca gtctatggta gctctcttta aaaggcaccg
       61 atactgccgc cacctccgcc tccagagaag ccaccaccag aacttccact tccagaagat
      121 acagagtagg tgcttgctgt atttgcgaca ctagcataat ggctcatttg cgcgcttgaa
      181 tgataaaaca gactgtgcca gccataagct acatagagat tgatatctgg attttccact
      241 tgaatctgat gaaccttcat caaatgacta accttgtccg catagccaaa taaggtcgca
      301 tagaccaaga ggcgattcca gaccacaata ctttccagtt cagcctgatc caatcgtgca
      361 atctcacgca acatattttc aaaactggtc cagagatagt agacctcagc tcccgcttca
      421 tttagaacac catcacgatt atctagtcga agcttccaat aatagaaaac agacaaaact
      481 aaccctagaa aaccaagtat tggcaaaggg aggtaaagat agccatgaac gtctaaactg
      541 tacaagaaca aaccaaatcc gataaatagg ggcaggatag tcaaggcacc catacccact
      601 tgcaaggcct tttccccacc agttaaagga cgataataat ctgggagccc ccagaaggaa
      661 actcgttttc tcactccttc ttgcatctgg ttcaatacct cttcaaaaga agatttgagt
      721 tgaagccctc ttgcttgaat ccgtttttca tcagaaactt tggctctacg ataaagacta
      781 tcagatacct tgtaatccgc aaacaaattg gaaagagttt cttctttttt acctgaaaaa
      841 gctagattta ggcagtcttt ctcaaagctt gacaaaccat cttcttttac tagcctcaaa
      901 ccaactgcat ctccttctga aatgatagag acattcccac ggtctatcac atctagcaag
      961 gtagcttgaa taagttgatc aaaggtgaat tttccagctc ccttgaccaa gggactcact
     1021 tcctccaagg aggtcgagta gactgcttct gataaaacca taggctctaa ttccattggt
     1081 ggttcataga gacgatgatt tttggcatat ttgactgaag gagtggtctt tcttctataa
     1141 ataaaataga agcagacact caataacaag gagatagaaa ggatcgaagg gaggacccaa
     1201 gtaacaagtt gtttactctg atctttttct ctaacaatcg agtcttctat cttattaaac
     1261 tcttctaaac gattcccttt caatccctga tccctagcgc tagcaaaatc ggtccgaggc
     1321 caataggcat gcaactcaac tccacgctta gccggaagat tgtctaaacg gatagtataa
     1381 tcaaggttac tcttttcaat cgttccctct ctaaaaagtt tccctgtatg gaaaaagagt
     1441 ttttcagctc ccttgtctcc ccttacatga aattcaaact tttcaataga ctctgaacta
     1501 tctgtcagag gttgccaatt taattcagcg atatcatcat aaaggaaaag taaatttttt
     1561 aagttccaga cgaggtcaac ttcaactatg tcgccctcct gacctggatt atagactctc
     1621 acagtataac catccgcttc ttctgttact tcgctagtca catctgctag ttctgcaccg
     1681 tttttcgcgg cctgaacctt tggatgaggg tcaatgtcaa acccgctagg catcttacca
     1741 gcacgtccaa gtcccacgat ttgtccctta aagtcctcct caaactggta aactatcttc
     1801 tgtctaaact ctgccgtatt atctgcatga atatacaaat ccccttgata agagtttatc
     1861 ttgaaatcaa tggcaaaaac agagagtgga agaaggcaaa acaagcctaa caccagtaag
     1921 aaaaaagttt ttttcatcaa ctaagccccc tttttatctt tcttatcatt atagcatttt
     1981 ttcgtaagta aaggcttact tatgttgaaa aattacgcat ttttcgataa aataggagac
     2041 agttattttt taatagatca gaataggaga aatcatgaga aaaatatact tatctatttt
     2101 cacaagtctc ttgctgatgc taggacttgt caatgttgct caagccgatg aatatttacg
     2161 catcgggatg gaagcagcat atgctccctt taactggacc caggatgatg atagcaacgg
     2221 agctgtcaaa atcgatggga ccaatcagta tgccaacgga tacgatgttc aaatcgccaa
     2281 gaaaatcgct aaggacttag gtaaaaaacc tttggttgtt aaaaccaagt gggaaggtct
     2341 agtccctgcc cttacttctg gtaagattga catgattatc gcaggtatga gtccaactgc
     2401 agaacgcaaa caagaaattg ccttttcgag cagttactac actagcgaac cagttttgct
     2461 tgtcaaaaaa gattctgcct acgcaagtgc taaatctttg gatgacttta acggtgcaaa
     2521 aatcacttct caacaagggg tctacctcta cgacttgatt gcacaaatcc caggtgctaa
     2581 aaaagaaaca gccatgggag acttcgctca aatgcgacaa gctcttgagg ctggtgtcat
     2641 tgatgcttat gtttctgaac gtccagaagc actgactgct gaagctgcga actctaagtt
     2701 caagatgatt caagtagaac ctggtttcaa aactggggaa gaagatacag ctatcgctat
     2761 cgggcttcgt aaaaatgaca atcgtattag ccaaatcaat gccagcattg aaaccatttc
     2821 aaaagatgac caagttgcct tgatggatcg tatgatcaag gaacaacctg ccgaagctac
     2881 aacaactgaa gagactagca gtagtttctt tagccaagtc gctaaaattc tttctgaaaa
     2941 ctggcaacaa ctcttgcgtg gtgctggtat cactctttta atctctatcg tcggaaccat
     3001 cataggtctc attattggac ttgccattgg tgtcttccgt actgctcctc tctctgaaaa
     3061 caaagccatt tatggccttc aaaaactagt cggctgggtt ctcaatgtct acattgaaat
     3121 tttccgtggt acgccaatga ttgttcaatc gatggttatc tactatggaa ctgcccaagc
     3181 tttcggtatc aaccttgacc gtacactagc tgctatcttc atcgtttcaa tcaataccgg
     3241 tgcctacatg actgaaattg tccgtggtgg tatcctggca gttgacaagg gacaatttga
     3301 agctgcgact gctcttggta tgactcataa ccaaaccatg tgtaagattg tcctacctca
     3361 ggttgtccgc aatatcctac cagcaactgg taatgaattt gtcatcaata tcaaagatac
     3421 atctgtattg aacgttatct ctgttgtcga actttatttc tcaggaaata ccgtggcaac
     3481 acaaacctat caatacttcc agacatttac aatcatcgcc gtgatttact ttgtcctcac
     3541 cttcaccgta acacgtatcc tacgctttat cgagcgcaga atggacatgg atacctacac
     3601 tacaggtgct aaccaaatgc aaacggagga tttgaaataa tgacacaagc aatccttgaa
     3661 attaaacacc tcaaaaaatc ctatggacaa aacgaagtgc taaaagacat ttctctcact
     3721 gtccacaagg gagaagttat ttctatcatc ggaagctctg gaagtgggaa atcaaccttc
     3781 ctacgctcca ttaacctact tgaaacgcca actgatggac aaatccttta tcatggacaa
     3841 aacgtcctcg aaaaaggcta tgacctcacg caataccgtg aaaagttagg gatggttttc
     3901 caatccttta acctctttga aaatctcaac gttcttgaaa acacaatcgt cgctcagaca
     3961 actgtcctta aacgcgaacg cacagaagct gaagaaattg ccaaagaaaa cctggaaaag
     4021 gtcggcatgg gagaacgcta ctggcaagcg agacccaaac aactctcagg tggtcaaaaa
     4081 caacgtgtgg ccatcgctcg tgccctttca atgaatcctg acgccattct ctttgatgaa
     4141 ccaacatcag ctctcgatcc agaaatggtt ggagaggtcc tcaaaatcat gcaagatctg
     4201 gctcaggaag gcttgaccat gattgtcgta acccatgaaa tggaatttgc ccgtgatgtc
     4261 tctcaccgtg ttatctttat ggataagggt gtgattgctg aagaaggtaa accagaagac
     4321 ctcttcacta atcctaaaga agaccgtaca aaagaatttc ttcaacgtta tctcatactc
     4381 aatgaaaatc aaagagcaaa ctaggcagct agccgcaggt tgctcaaaac actgttttga
     4441 ggttgcagat agagctgacg tggtttgaag agattttcga agagtatcaa ataaaaagaa
     4501 aaggctgcat caaccgtgca gtctttttgc tgtcctcaaa atgaaaaggc agattctcta
     4561 tctctactac ttgaaggtca agaatccacc gttatccaaa gattaatctt caaatttttc
     4621 atgatttttt tcatagaaat caattaagcc tagggctgtt tcaaatgaaa tattttttac
     4681 ttttgcacga ccctgcgcca gagcaatgat agacatttca cgcgcattcg tttctttaga
     4741 gatacggtag cctgtgattt tcttatcacg aacccagcca acaactgatt ctactttttc
     4801 aaagtttgac ttagccatgt ttttctccta ttttcttctt tataatattt aattgtatac
     4861 gtttttacta cttttgtcaa taaaaaaaac atatattcaa cgaaaataat tagttcagaa
     4921 ttttcttact tcctttttaa atccgataat atataggttt tgctagcctc tacaccataa
     4981 atatttgcta ataaaaatac tgtattatta ccctcttaag gtgcaaaatt attcaagttc
     5041 ttaaaaaatg cttctctatt tccgtaagat agcttatttc ttcgatttaa gaactgaaga
     5101 tgatagttct aacctttaga aatccaagcc ttctctagct caaaaactcc tatctttctt
     5161 cctcaataaa tcatctgaga gataggtatt ccttatatcc ttcaaattca tcactccttt
     5221 ggatattgag gtgctagcct agaagcagac acccgattat ctaaaccatc cttaatagag
     5281 atgacaagac agataagctc agttaattac ttatatatct ttttaatatg gtatatttgt
     5341 caacaaaaag aaatcaaatc ataccttata ctcaatgaaa atcaaagagc aaactaggaa
     5401 gctagccgca aattgctcaa aacactgttt tgaggtttca gatagagcta acgtggtttg
     5461 aagagatttt cgaagagtat taaagacagt atgactatgc ttgtcaatag ataggaaatc
     5521 aaaatgaagg atggaaatct gagccaaaca tcataagtgc tataatgaac agaagtaaga
     5581 attgcacgat aagttttcta aaaccatagg aatcgtcccc tttcttcatc ttcattatag
     5641 cacatataca tcagttgtac aaataatatg atattttttt attagtcctc agacaagcat
     5701 attataaagc gtttcattac catttaagtt aatataagct ggatcaaaac cttccattct
     5761 acggatcaaa cctgcataat catgcttatc tgccaaagcg atcccaatca atactgggcc
     5821 tgttcccttg ctagctcgtt tgatatactc aaaacgtgtg atatcatcat ttggccccag
     5881 gatatcattt acaaactcac gcaaagctcc tggacgctgt gggaaattga ccacaaagta
     5941 atgtttgata ccatcataaa tcaaggcacg ctcttccatt tctggcatac ggttgatatc
     6001 attatttcct ccagaaatga tacaacaaat ggttttcccc ttaatatatt cagctaaaac
     6061 ctctaaagag gcgatactag ccgctccagc aggttctgcg actatccctt gcttagagta
     6121 aaggtcaatc aaggtttcag aaatcaatcc ctcatcgaca cctaccaaag tttgaatatg
     6181 ttgacgagtt gcttcatagg tcaactgacc taccttttgc acagcaatcc catccgcaaa
     6241 tttatcaatt tccttgagtt tgactggacc tccagcctca aaggcagctt tcatggaacg
     6301 cgctccattc gcctctactc cgataacctc aatctctgga cttgtttcct tgatataggt
     6361 agaaaccccg gcaatgagac cgccaccacc aacaggaacc aagacagcat caaaatcaat
     6421 cgattctttt cgagcttctt ctaaaatctc ataagcaact gttccttgac ctgcttgaac
     6481 atgagcatca tcaaaaggat caataaaggt acgattttca gagactgtaa attcttgagc
     6541 tgctttggct gaggcatcaa aggtatctcc aactagttta atagttacaa aatccccacc
     6601 aaaaaagcga acctgaccaa tcttttgttg tggcgtagta ataggcataa agatagtagc
     6661 aggaattttc atttcattac aagtataggc tactccctgc gcatgatttc ccgcagaagc
     6721 gcagactacc ccacgttcac gttcttcctt gctgagctgg gaaatggcat aataggcacc
     6781 acgaatttta aaggagcgaa cacgctgggc attttctttt ttcaaataaa tcttagcacc
     6841 atacttctcc gataaataat gatcgtaatc cagtggagta ttcacaacca caccgttcaa
     6901 gaccttgtga gccttgatta tatcttttga acttaacata taaaacctct ttttctataa
     6961 aaaacagtca ctaatgactg ttttttagtt attcatctcc gaaaacttca gtaacacttt
     7021 catggtattt atgagccata cgaatcgaaa actctttagg aagttcataa cgatttgtgg
     7081 aaatccaatc atataaccat tctaccaaac tttcttcact atcattacga tggaagataa
     7141 aatagtttaa aatttcttta tattctacat cattcaaatc caacgtgtct acaaattgac
     7201 tacgaggaac aaaattagaa tctaattttc ttagttgatc tgtcaattct cccaattgta
     7261 aatccaactg aaaaaatagt ttttgcagtt gcctatcagt ttcatcacat cctgtcttga
     7321 tagaaaacaa attggtaata ttcatatgat ttcaacccct aaataagtac atctaatatc
     7381 ccacgaatag ctgaagctaa agttttcgca gtccagtcat ttaaacccga ttctttcaat
     7441 ccagatgcaa taatttgctc tatttgatat aaaccgccat ctatcgtctc atttattctg
     7501 cgaagaggac cttcaatata ggataaagct tctccgaatc taacagctga tttaggtcct
     7561 aatgatttac caactatatt tgttaatgtt ttttatttct caaaatccat ttcgctatat
     7621 aacgagcaga tttagtcgca ccagctctct caaacggaga atgaatttca agaccttctt
     7681 ctctagctat ttgtgccaat ttgaagaatt gttcaaaggt catatgcaac ctaccatctt
     7741 caaaattagc atcatcataa atgttaatta cagcattttc atcatacgac caatctgctt
     7801 tattttggtc tgctagcact attaccgacg gtgtaattac attatacaac tagaaccaat
     7861 aataacgatg caatttttct cataatcttt ttcataaaat catctccagc gctatatatt
     7921 tctaattagt tatagatttt gaatgcatca tcgtcgtttt taccaacaaa tggcattgct
     7981 ttacgcaatt ctgcaccaac tttttcaatt tcaaggttag ctgcttgttc acggtaagca
     8041 gtcaattttg gacgtccagc tttatagtca tttacaaagt catttgcaaa tttaccattt
     8101 tggatgtctg ccaagacagc cttcatattt tctttaactt gttcagtgat tacacgtgga
     8161 cctgatacat agtcaccgta ttcagcagtg tttgaaatag attgacgcat tttcttgaat
     8221 ccaccttcgt agatcaagtc aacgatcaat ttcatttcgt gaagaacttc aaagtaagcc
     8281 aattctggag cgtaacctgc ttctgtcaag acttcgaaac ctgcttcgat aagggcagtc
     8341 aaaccaccac aaagtacagc ttgttcacca aacaaatctt cttcagtttc ttctttgtaa
     8401 gttgtttcaa gaagacctac acgagccgct ccaacacctt tacaccagtc catagcaatg
     8461 tttttagcat ttcctgttgc atcttggtat actgcataaa gagctggaac accaaatcct
     8521 tcttcgtaag tacgacgtac caagtgtccc ggtcctttag gagcacacat gaagacatct
     8581 acatccgcag gaactttgat aaattcaaag tggatgttga aaccatgggc aaatccaact
     8641 gcgtttccag cttccaagtt tggagcgatt tctgcttcgt acaattcttg ttgaatttcg
     8701 tctggcgcca agatcatgat aacatcagcc aacttagtag cttctactac tgtgtaagta
     8761 tcaaatccat cttcttttgc tttatcaaaa gatttacctg gacgtacacc gataataacg
     8821 tcacgacctg aatcacgcaa gttttgagca tgcgcatgtc cttgtgaacc ataaccgata
     8881 acggcgattt ttttaccgtc aagtgctgct actttaacat ctttttcata ttccatttga
     8941 actgtcatag cttttctctc ttttctatta tttattgcct tttaggctgg tttaataaat
     9001 ttaagttgga tttttaatcg cgggtaaatc cagttgcacc cgttcgagca atattgcgaa
     9061 taccgtatgg gcgaatgact cgcaataggg cttcgctctt ttctgcattt cccgtcatct
     9121 gaatggtaat cgagcttggc gctacgtcta ccactgttgc acggaaaggt tgaataatcg
     9181 ctaaaatctc agctctcttc tcagctggcg ctgacatctt aaccaaaatc acctcgcgct
     9241 ccaaatgagg cttgtctgta atatctcgaa tgcgaatcac atcaatctga cgattgagct
     9301 gtttgatgat ttgctccact tcatcatgag aagcaacatc aataataata gtgatacgcg
     9361 atacattcgg atcttctgtt gctccaacag agatgctttc aatattaacc tgacgacgag
     9421 ataggacacc tgtaaagcga ttgaggactc ctgaacgatt ttgtagtttt gctgttaaca
     9481 ttctacgcat ggaactgcac ccccaacatc tcatgattac tcttaccagc cggtaccatt
     9541 ggtaacacct gttccttacg agaaatatct acctcaatta gcataggaac atcctcagtg
     9601 atgacttcaa ggtcttgagc caaggtctca ggattgtcaa acttatagtt tttaatacca
     9661 taagcctgcg ccatcaattg gaaatcagga agggtatcaa agaccgactc tgatgttctg
     9721 ccttcataga aggattcctg ccactggcga accattccaa gtgaatgatt gttcagcata
     9781 accaccttga ttggcacctt gtaaatattc aaaatagcca actcctggtt ggtcatttgg
     9841 aaaccaccat ccccaacaaa caagactact tccttatctg ggttagcaat tttagcaccg
     9901 attgctgctg gaattccaaa gcccattgtt cccaaaccac ctgaagtcac taactgacgc
     9961 tcattttggt agggataata ctgagctgtc cacatttggt gttgaccaac gtctgttacc
    10021 acaatggcat ctccattcgt caattcacca attcgttcaa taactgcttg cggttgaacc
    10081 acacgctctt tcttgtcata agaacgaaca cgattcttgt ctttagtgac tttctcaatc
    10141 cacttttcag tattgttgtg aactgttggt tctgctagca acatttgcaa ggccttctta
    10201 gcatctccaa ctacaggaat gtctgcactg ataatcttgc caatctcagc tgggtcaata
    10261 tcaatgtggg caaccttagc attcttagcg aaagtcttag gattccccgt caaacggtca
    10321 tcgaaacgag aaccaatact aatcataaag tccgcttccg tcatggcaat atttgctgcg
    10381 aatgacccgt gcatgcctcc cattccaaga aagagtgggt gactcgttgc aatcgttcct
    10441 tgtcccaaaa gactggttac cactggaatt tgatagcgtt ctgcaaattc atttagttcc
    10501 gtagcagcct cagcataact aattccacca ccagctaaca agactggctt tttagccttg
    10561 gacaattgct tcaagatttt cttgatttgc atatcattcg gctcaagagt cggctgataa
    10621 cttggtaaat tcacttctgg tgaataaatg aagtctgttt ctaaagcaga tatgtctttt
    10681 ggtaggtcaa ttacaactgg ccctggacgg cctgtagttg cgatatggac agcttccgta
    10741 atgatacgcg gaatatcagc tgtctcacga acttggtaat tgtacttagt gattggcatg
    10801 gtaattccta cgatgtctgc ctcctgaaag gcatccttcc caatccctgc tcgcgccacc
    10861 tgacctgtaa agaccaaaag gggaacgcta tcgctcatag catccgcaat ccctgtaatg
    10921 gcatttgttg ctcctggtcc actagtgacg acggcaacac ccaactttcc agttgatttg
    10981 gcataacctt cagcttcatg caaacaacct tgctcatggc gccctagaat gtggcgaatg
    11041 cctttaaaat tatatatcgc atcataaaaa ggcaaaaccg caccaccagg ataaccaaag
    11101 atggtatcaa ctcctaaatc acgaagtgtt tccaaaacta ggtccgaccc cgtcttagga
    11161 gattctaaac tgattttctc cattgttccc ctttctttcc tcttaaaaat aacttgttac
    11221 tatcatacca ttttttcaaa atttttcaag ataaaagaag aaattttctg aattttctat
    11281 tttaacgttt atttatgaat gttatttttg tttttattaa aaagataccg atttcattta
    11341 ctaaaaaaga aaaaagaact gatttctcag tccttcatta atcttattcc acactaaata
    11401 ggtatgggta aacaggttgt tgaccttggt gaatctcgac ttcaacgtct tcgaattctt
    11461 ctacgatttc ttgagcgatt tcattggcaa gttcttcgct tccgtcttca ccgacataga
    11521 aggttacgat ttcactatct tcatccaaca tatgtttcaa ggtttcagtc aatgtttggt
    11581 gcatatcagg gtttgacaca agaatttttc catccaccat acctagatta tcgttttcat
    11641 ggatttctaa gccatcgatc gttgtatcac gcacggctgt tgtgacgctt ccgctaacga
    11701 catcgctaag agcagctgtc atacgctctt ggttttcttc aatggacttg cttggatcaa
    11761 aggcaagaag acttgtcata ccttgaggaa gagtgcgagc ctctaccact actgctggtt
    11821 gctccaaaac ttctgccgca gattgagctg ccatgaagat gttcttgttg tttggcaaga
    11881 agatgatgtt acgggcattg acctgttcaa cagccttgat aaagtcttct gttgaagggt
    11941 tcatggtttg accgccttcg ataacataat ccacgccttg agaacagaag atatctgcta
    12001 gacctttacc agccaccaca gcaatcaaag catactcttt ttcttcagcc gacttgataa
    12061 cttgagtagc ttctttctca acctgtgctt cgtgttggtt acgcatattg tcaactttta
    12121 ccttgaccaa gctaccatat ttgagacctt cttgcataac aagtcctgga tcttctgtat
    12181 gaacatggac tttgacaatt tcatcatcgt taacaacgag gagagaatcc ccaagctcat
    12241 ccaagtagtt acggaattca tcgtagtcaa aatctttagc ataggttgga ccttgcttaa
    12301 gagctaccat gatttcagta cagtaaccaa acgtgatgtc ctcagtcgct acgtgaccag
    12361 ctacagactt atgatgctct acattgatca tctcactcat gttggcagga gtcgctacaa
    12421 agtcctcaga tgcaatatat tcgccagtaa gggctgaaag gaaaccttcg tagatgaaga
    12481 ccaatccttg accacctgag tccacaacgc caacttcttt caatactgga agcatgtctg
    12541 gtgttttagc tagagctgtt ttagcacctt ccaaggctgc gcgcatgact tcaacagtgt
    12601 catctgtttg ctcagctttt ttcttagcac cgatagcagc tccacgagaa actgtcaaaa
    12661 tcgttccttc aacaggtttc atcactgcct tataggcaac ttccacacct gattggaagg
    12721 ccagagccaa gtcttgacct gttaactcgt ctttatcctt gatagcttgg gaaaatccac
    12781 ggaaaagctg agacgtaatc actcctgagt tcccacgcgc acccatcaaa agccctttgg
    12841 caagaatgct cgctacttct ccaactgtag aagctggctt gtctgcaact tctttagcac
    12901 cattttcaat ggtcattccc atatttgtcc cagtatctcc atctggaact ggaaagacgt
    12961 ttaatgaatt gacatattca gcttgcttat tcaagcgagt tgatgcagcc tgcaccattt
    13021 cttgaaataa gctagtagta atttttgaca cggttattct cctacaactt tgatattttg
    13081 aatgtagaca tttacagtct gagcagtaat tccaagctgg ttttccaagc taaaggcaac
    13141 acgctcttga atgttttttg acacttcact aatctttgtt ccgtagctta acacggtata
    13201 tacatcaact gcaatactgc catcttcggc tgcctttacg acgacacctt tagaataatt
    13261 ttccttacct agcagggctt ggaaattatc tttgagggca tttttactag ccataccgac
    13321 cacaccaaaa atctcagttg ctgctccacc tacgacggtt gcaatcactt catctgttag
    13381 ttcgatttga ccatcttttg tattaatttt tacagtcatc ctttttacct caactagttg
    13441 atactctatt ttatcatatt tcagcccaag tgtaaaagca gaatgatgta tcagcggata
    13501 tttactctat ttttcaaacg atgttatacc cacaataaaa gaaaaaagac cctaaggtct
    13561 cctttgcttt tattattaaa cgcgttcaac tttacctgat ttcaaagcac gagctgaagc
    13621 ccaaactttt ttaggtttac catcgataag aacagtaact ttttgaaggt ttggttttac
    13681 ggcacgtttt gtttggttca tcgcgtgtga acggttgttt cctgatacag tcttacgacc
    13741 tgtaaagtaa catactttag ccattgtgtt ttcctcctat tagatctaat atagcggatg
    13801 tgctagcacc acataccgta ctatgttatc acactttctt gttttttgca agggaattgg
    13861 aagatttttt atttgtgtct taaatcaggt cttgcgtgac attttctgct ctccacatgc
    13921 catcgttgat taacagaaca ccagaattaa aattatgtgt ataaaaatca tctctaactg
    13981 cagctaaggg tatagccgtc aagtccaaat cccacagctc atctatcgat tttcttacaa
    14041 caatatctga atccaaatac agtacacgag actcgcttac atactttgga ataaaatacc
    14101 taaaaaagcc gcatatgaaa gtccctcaaa ggggagacga taacctttca gaatattact
    14161 gtcaatctaa acattcacaa tctcactatt caaagtctct agtctttttt ccatcaattg
    14221 gaaccattct cgcggaaggt catcattaaa aacataaaac ttaagattat aatgatgaac
    14281 acaaagagat tttattgttg tttcaacttt atccatataa gcattatctg cacctaagac
    14341 aatcgctttt ttctcttttt tctcttcttt cactttttat ctcatttctt tttattccca
    14401 tcatatgttt ctacgtaacc attattttcg cctattcgtt cgtaaaacca taccagtgga
    14461 gattttagat gaagtcccat tacggtttac aatttttaca ttacgacacg gagttttaca
    14521 aatcgatttc atttgccaaa cgtagttagt gaggcagtta gctagttcgc caaatagcga
    14581 ctagcgtcca acaatttgga actttagttc caattgttgg tactgagtca catcttctcc
    14641 tctaactcta cgtctggata cttgtcagca aaccagcgga gggcaaagtc attttcaaag
    14701 agaaagactg gttggtcaaa acggtctttg gctaagatat tgcgacttga cgacatccgt
    14761 tcatccaagt cctcaggctt gatccaacga acggtctttt tacccattgg gttcataact
    14821 acttctgcat tgtactcgcc ttccatgcgg tgtttaaaga cttcaaactg gagttgacct
    14881 acagcgccta gcatgtactc acctgtttgg taattcttat aaagctgaac ggctccttct
    14941 tgcaccaatt gctcaatccc cttgtggaag gatttttgct tcataacatt cttagcagaa
    15001 actttcatga aaatttcagg agtaaaggtt ggcagtggtt caaattcaaa cttgttttta
    15061 ccaactgtca aggtatcccc aacttgataa gtaccggtat cgtaaacccc gataatatca
    15121 cctgccacgg cattgatcac attctcacga ctttccgcca taaactgggt aacattagat
    15181 agtttggccc ccttaccagt acgagggaga ttgacactca tgccacgctc aaattcgcct
    15241 gatacgatac ggacaaaggc aatacggtca cggtgacgag gatccatgtt ggcttggatt
    15301 ttaaagacaa agcctgagaa atccttgtca taaggatcca caatttcacc gtctgttttc
    15361 ttgtgaccat gtggttctgg agcaaacttg aggaagattt caaggaaggt ctgcacacca
    15421 aagtttgtca gggctgaacc gaaaaagaca ggcgtcaatt ctccagccag aatagcttcc
    15481 tctgaaaact cattcccagc ttcatttaaa agctcaatgt catccttgac ttgctcgtag
    15541 aaaggattgc taccaaagag tttgtccccg tcttctagac tggcaaaacg ctcatcccct
    15601 ttgtaaagct ctaaacgttg gttatagagg tcatacaagc cctcaaaggc tttccccatc
    15661 ccgataggcc agttcatagg gtagctagca atgcccaaga tttcttccaa ttcttgcaag
    15721 agatccaaag gctcacgacc gtcacggtcc agcttgttca taaaggtaaa aactggaatg
    15781 ccacgatgtt tcacaacctc aaacaatttc ttggtttgag cctcgatccc cttggcagag
    15841 tccacgacca tgaccgcagc atccaccgcc atcaaggtac gataggtatc ttctgagaag
    15901 tcctcgtgcc ctggcgtgtc taagatattc acgcgcttgc cgtcgtagtc aaattgcata
    15961 acagatgaag taacagaaat cccacgttgc ttctcgatat ccatccagtc agatttagca
    16021 aaagtccctg ttttcttccc ttttaccgta ccagcctcac gaatctcacc cccaaagtag
    16081 agtaactgct cagtgatggt tgttttcccc gcgtccgggt gggagataat ggcaaaggta
    16141 cgacgtttct taatttcttc ttgaatattc ataagttctc tttctttgat tctctatttt
    16201 tcttgtttca atagctgaga atgattttta cattggattt taccattcct ttcaacattc
    16261 cattatatcg gattttagca tttttttcaa tttctatttc ttttcacttc cccctccctt
    16321 atttatagga aaatatggta aaatagaaca gactaaaaat catcatttca cgaaaggatg
    16381 caagatgaaa attacgcaag aagaggtaac acacgttgcc aatctttcaa aattaagatt
    16441 ctctgaagaa gaaactgctg cctttgcgac caccttgtct aagattgttg acatggttga
    16501 attgctgggc gaagttgaca caactggtgt cgcacctact acgactatgg ctgaccgcaa
    16561 gactgtactc cgccctgatg tggccgaaga aggaacagac cgtgatcgct tgtttaaaaa
    16621 cgtacctgaa caagacaact actatatcaa ggtgccagct atcctagacg atggaggaga
    16681 tgcctaatga cttttaacaa taaaactatt gaagagttgc acaatctcct tgtctctaag
    16741 gaaatttctg caacagaatt gacccaagca acacttgaaa atatcaagtc tcgtgaggaa
    16801 gccctcaatt catttgtcac catcgctgag gagcaagctc ttgttcaagc taaagccatt
    16861 gatgaagctg gaattgatgc taacaatgtc ctttcaggaa ttccacttgc tgttaaggat
    16921 aacatctcta cagacggtat tctcacaact gctgcctcaa aaatgctcta caactatgag
    16981 ccaatctttg atgcgacagc tgttgccaat gcaaaaacca aaggcatgat tgtcgttgga
    17041 aagaccaaca tggacgaatt tgctatgggt ggttccggtg aaacttcaca ctacggagca
    17101 actaaaaacg cttgggacca cagcaaggtt cctggtgggt catcaagtgg ttctgccgca
    17161 gctgtagcct caggacaagt tcgcttgtca cttggttctg atactggtgg ttccatccgc
    17221 caacctgctg ccttcaacgg aatcgttggt ctcaaaccaa cctacggaac agtttcacgt
    17281 ttcggtctca ttgcctttgg tagctcatta gaccagattg gaccttttgc tcctactgtt
    17341 aaggaaaatg ccctcttgct caacgctatt gccagcgaag atactaaaga ctctacttct
    17401 gctcctgtcc gcatcgccga ctttacttca aaaatcggcc aagacattaa gggcatgaaa
    17461 attgctttgc ctaaggaata cctaggcgaa ggaattgatc cagaggttaa ggaaacaatc
    17521 ttaaacgcgg ccaaacactt tgaaaaattg ggtgctatcg tcgaagaagt cagccttcct
    17581 cactctaaat acggtgttgc cgtttattac atcatcgctt catcagaagc ttcatcaaac
    17641 ttgcaacgtt ttgacggtat ccgttacggc taccgcgcag aagatgcgac taatcttgat
    17701 gaaatctatg taaacagccg tagccaaggt tttggtgaag aagtgaagcg ccgtatcatg
    17761 ctgggtactt tcagtctttc atcaggttac tacgatgcct actacaagaa ggctggacag
    17821 gtccgtacac ttatcattca agatttcgaa aaagtcttcg cggattacga tttgattttg
    17881 ggtccaactg ctccaagtgt tgcctatgac ttggattctc tcaaccatga cccagttgcc
    17941 atgtacttag ccgacctctt gaccatacct gtaaacttgg caggactgcc tggaatttcg
    18001 attcctgctg gattctctca aggtctacct gtcggactcc aattgattgg tcccaagtac
    18061 tctgaggaaa ccatttacca agctgctgct gcttttgaag caacaacaga ctaccacaaa
    18121 caacaacccg tgatttttgg aggtgacaac taatgaactt tgaaacagtc atcggacttg
    18181 aagtccacgt agagctcaac accaattcaa aaatcttctc acctacttct gcccactttg
    18241 gaaatgacca aaatgccaac actaacgtga ttgactggtc tttcccagga gttctaccag
    18301 ttctcaataa aggggttgtt gatgccggta tcaaggctgc tcttgccctc aacatggacc
    18361 tccacaaaaa aatgcacttt gaccgcaaga actacttcta ccctgataat cccaaagcct
    18421 accaaatttc tcagtttgat gagccaatcg gttataacgg ctggattgaa gtcgagctag
    18481 aagacggtac gaccaagaaa attggtatcg aacgcgccca cttagaggaa gacgctggta
    18541 aaaacaccca cggtacagac ggctactctt acgttgacct taaccgccaa ggggtacctt
    18601 tgattgagat tgtatctgaa gccgatatgc gttcgccaga ggaggcctat gcttatctga
    18661 cagccctcaa ggaagttatc cagtacgctg gcatttctga cgttaagatg gaagaaggtt
    18721 ctatgcgtgt ggatgccaac atctcccttc gtccttatgg tcaagagaaa ttcggtacca
    18781 agactgaatt gaagaacctc aactccttct caaacgttcg taaaggtctt gaatacgaag
    18841 tccaacgcca ggctgaaatt cttcgctcag gtggtcaaat ccgccaagaa acacgccgtt
    18901 acgatgaagc gaataaagca accatcctca tgcgtgtcaa ggaaggggct gctgactacc
    18961 gctacttccc agaaccagac ctacccctct ttgaaatttc tgacgagtgg attgaggaaa
    19021 tgcggactga gttgccagag tttccaaaag aacgtcgtgc gcgttatgta tctgaccttg
    19081 gtttatcaga ctacgatgct agtcagttga ctgctaataa agtcacttct gacttctttg
    19141 aaaaagctgt tgccctaggt ggtgatgcca aacaagtctc taactggctc caaggggaag
    19201 tcgctcagtt cttgaatgct gaaggtaaaa cactggaaca aatcgaattg acaccagaaa
    19261 acttggttga aatgattgcc atcatcgaag acggtactat ttcatctaag attgccaaga
    19321 aagtctttgt ccatctagct aaaaatggcg gtggcgcgcg tgaatacgtg gaaaaagcag
    19381 gtatggttca aatttcagat ccagctatct tgatcccaat catccaccaa gtctttgccg
    19441 ataacgaagc tgctgttgcc gacttcaagt caggcaaacg taacgccgac aaagccttta
    19501 caggattcct tatgaaggca accaaaggcc aagccaaccc acaagttgcc cttaaactac
    19561 ttgcacagga attggcgaag ttgaaagaaa actagacaga acaaaaccag ccctaaggtt
    19621 ggttttttct tctctaccaa ctcccaataa ctattttggc tttatttcca gagtatttta
    19681 tggtaaaatg aagagtaata atatttatta aagaggtaaa aacatgattg aagcaagtaa
    19741 attaaaagct ggtatgacct ttgaaacagc tgacggcaaa ttgattcgcg ttttggaagc
    19801 tagtcaccac aagccaggta aaggaaacac gatcatgcgt atgaaattgc gtgatgtccg
    19861 tactggttct acatttgaca caagctaccg tccagaggaa aaatttgaac aagctattat
    19921 cgagactgtc ccagctcaat acttgtacaa aatggatgac acagcatact tcatgaatac
    19981 agaaacttac gaccagtacg aaatccctgt agtcaatgtt gaaaacgaat tgctttacat
    20041 ccttgaaaac tctgatgtga aaatccaatt ctacggaact gaagtgatcg gtgtcaccgt
    20101 tcctactact gttgagttga cagttgctga aactcaacca tctatcaaag gtgctactgt
    20161 tacaggttct ggtaaaccag caacgatgga aactggactt gtcgtaaacg ttccagactt
    20221 catcgaagca ggacaaaaac tcgttatcaa cactgcagaa ggaacttacg tttctcgtgc
    20281 ctaatctcta gaaagaggtc attctatggg aattgaagaa caacttggcg aaatcgttat
    20341 cgccccacgt gtacttgaaa aaatcattgc tatcgctact gcaaaggtag agggtgttca
    20401 ctctttttca aacagatcag tgtctgatac cctttcaaaa ctttcactcg gccgtggcgt
    20461 ttatcttaaa aacgtggacg aagaactcac agcagatatc tatctctacc ttgagtacgg
    20521 agtaaaagtt cctaaggtag cggttgctat ccagaaagct gtcaaagatg ccgtccgtaa
    20581 tatggctgat gtagaactcg ctgctatcaa tattcacgtt gcaggtatcg tcccagataa
    20641 aacaccaaaa ccagaattga aagatctatt tgacgaggac ttcctcaatg actagtccac
    20701 tattagaatc tagacgccaa ctccgtaaat gcgcttttca agctctcatg agccttgagt
    20761 tcggtacgaa tgtcgaaact gcttgtcgtt tcgcctatac tcatgatcgt gaagatacgg
    20821 atgtacaact tccagccttt ttgatagacc tcgtttctgg tgttcaagct aaaaaggaag
    20881 aactagataa gcaaatcact cagcatttaa aagtaggttg gaccattgaa cgcttaacgc
    20941 tcgtggagag aaacctcctt cgcttgggag tttttgaaat cacttcattt gacactcctc
    21001 agctggttgc tgttaatgaa gctatcgagc ttgcaaagga cttctccgat caaaaatctg
    21061 cccgttttat caatggactg ctcagccagt ttgtaacaga agaacaataa aaagaaaaag
    21121 tgtttgatag atatcaaaca ctttttcttt gcctcccact atctaaaaaa atgataatag
    21181 atataattgt aaacaaaaat ccagataggt tttgcatgat tgagaaagtt aaaaaaacta
    21241 tggcagagaa tcgttaatct cagattgtcg gtagaacgat aaacaagggc aaaaaagaaa
    21301 ccaatcagac tataatataa taaactaatt ggatctctgt gagatagtat caaatggcta
    21361 atcccaaaga taaggcctga taagatgaca tctaaatagt actttgactt aggaaagaag
    21421 gtattcataa aataccctct atcaagagtc tcctcaaaaa caggaccgat gattacaagc
    21481 aggacaaaag ataagatagt cgataaaaag gttggttgtc catttgaaag aaccacggta
    21541 aaatactcat catgaatatt cctatggtta atcaaatgag catagcgtgc ctaaaaatta
    21601 ccgagaatct gataaaccac ataagttgca aataaggaga agacaaatga ccagtcccag
    21661 ctctttttct tttttaacct ccaaattaat agaaaaggaa acttcccact aatcccactg
    21721 ttaaaataag agaatagaca tcagctccta accctaaaat gatcgtcaca tacaatccaa
    21781 ttgtttgtgg taaataggta gatagtaaaa taataagcaa aaatattcca aattgtctta
    21841 gtttctttgt gtttctcatc gtactttttt gaaagattac cctgttcgga agccgtactt
    21901 ccaagcatct atataagaat taagtgcccc ttgcctcata tagggagcaa attctctata
    21961 atataaccat ctactatatc catcttccca aacagcaaga ccacctgaag tttgctccaa
    22021 gtcctcagtt gaaagaactg taaatgtttc tgtacctgtc attgcaagta ccttcttaaa
    22081 atagattgtt gtaggctcac atttatagta tatttctttt tttgtctatt ttatagtcta
    22141 tctcctcaac tggcaatttt tcgacctgaa ttgcattttt ccataaaaaa tgagaccttt
    22201 ctagtctcat ttagtcattc ttagtatttt ctaaatcgtt gatagcgttc ttccagcaac
    22261 tcttctagcg gtttttgtga aagtctagcc agctccgttt ggagttcttt tttgacactc
    22321 ttaattagtt ctttactaga aagtcctact tcagaaatca ccttatccac cacgtccatt
    22381 tctaacagtt catgcgaagt gattttcatc agttctgctg cttccatggc gcgagtaccg
    22441 tccttccata aaatggaagc aaagccttct ggactgagaa tggcatagat agaattttcc
    22501 agcatccaga cacggtccgc gacagctaga gccagagccc cgcctgaacc accttcaccg
    22561 ataataatgg cgataatagg aactttcagg tcactcattt ccatgagatt gcgagcgata
    22621 gcttcccctt gaccacgttc ttccgctccg acaccaggat aagcacctgc tgtattgata
    22681 aaggtcacaa ctggacggcc aaatttctca gcctgtttca tcaaccgcag tgcctttcgg
    22741 tagccttctg gatgtggttg gccaaaattc cgtttgaggt tgtcttgcaa actcttgcct
    22801 ttttggatac caaccactgt tacagcttgg tctccaagcc aaccaatacc accaacaact
    22861 gcaccatcat cacgaaaaga acggtcacca tgtaattgga taaattcatc aaaaatgcct
    22921 gtcgcaaagt ccaaggttgt caagcgactc tgctcacgcg cttctctgac tatttttgca
    22981 atattcatct aggactccct ccatgcaatc tgactaggct agcaatcgta tctggtaagt
    23041 ctcttctttt gacaatagca tccacaaagc catgttctaa taggaattct gccttttgga
    23101 aatcctcagg caagctttca cgaaccgtat tttcaatcac acgacgccca gcaaaaccaa
    23161 ccaagctctg tggttcagcc agaatgatat cgccttccat agcgaaagaa gctgtcacac
    23221 caccagtcgt tggatctgtc aaaatggtca ggtaaaagag accagcattt gaatggcgtt
    23281 taaccgctgc agagatctta gccatctgca tgagactcat gattccttcc tgcatacggg
    23341 ctccaccaga ggctgtgaat aggacaactg gtaatttttc gacagtcgca tactcaaaca
    23401 aacgagtgat tttttcacct acaaccgtac ccatagaagc catgataaaa ttagaatcca
    23461 taatcccaag agccacagtc tgacctttaa taagagcagt tcctgtcaca acggcttcat
    23521 gcagacctgt tttttcacgc atagatgcca gtttcttttg gtaaccaggg aaatgcaagg
    23581 gatccttgct ttcaatccct gtaaacaatt ctttgaaggt tcccatatca atcgtcaaag
    23641 ccaagcgttc ttgggcagaa atacgaaagg tatagctaca gtgcggacag atacgttcac
    23701 ttcccagatc cttctgatag atggtatgct tacagcctgg acactgggaa aataattcat
    23761 ctggaacctc tggcttagct tgaggttttt ccctaaccga acgattggga ttgattcgaa
    23821 tatacttatc ttttttacta aatagagcca ttgattcccc ttttcggttt aaactcttaa
    23881 agtcatttta ttctttttct tgatatttag gtaagaaggt ttccatcaag aaggaagtat
    23941 cataatcccc agcaatgaca ttgcgatctg aaatgagatc aagctggaaa tctgcattgg
    24001 tctgcactcc ttcaatctct aattcataga gggcacgttg cattttcatc aaggcgtcaa
    24061 aacgattttc gccgtgtact atgattttgg caatcatact atcataataa ggcggaatgg
    24121 tataacctgg ataaactgct gaatccacgc gcaagccaac tccaccactt ggcagataga
    24181 gattagtaat cttacctgga cttggagcaa agttaaaggc tgggttttct gcattgatac
    24241 gacactcgat ggcatgaccg cgtaggacaa tatcttcttg cttaacagac aaaggctgac
    24301 ctgccgcaat gcaaatctgt tccttaacga tatcaacacc tgaaacaaac tctgttactg
    24361 gatgttctac ctgaacacga gtattcatct ccatgaaata gaaattgcta cttgcttcat
    24421 caagaagaaa ttcaatggtt cctgcattct catagccaac aaactctgcc gctcgaacag
    24481 cagcagcacc tatttcatga cgcagcgttt ttccgattgc aatcgaggga ctttcttcca
    24541 aaaccttttg gttattcctt tgaagagaac aatcccgttc acccaagtga atcacatgtc
    24601 catgctcatc acctaggatt tgaacctcaa tgtgccgagc tggatagata acccgttcta
    24661 tgtacatggc accattgcca taattggcct tggcctcact agaggcagtt tcaaaggcag
    24721 aaacgaggtc atctggtttt tcaaccttac gaatcccttt accacctcca cctgctgaag
    24781 ccttgagcat aacaggatag ccaatttttt cagcaacaat caaagcttct tcagagttat
    24841 gcacttctcc atctgaacct ggtataacag gcacacctgc tttaatcatc tgagcacgcg
    24901 cattgatctt atcccccatc atatccataa catgaccaga tggaccgata aacttgatac
    24961 ctacttcttc acacatggtc gcaaatttgg aattttcact gagaaatcca aaaccagggt
    25021 gaatagcttc tgcctcagtc aagactgcag ctgatagaac tgcattaata ttgagataag
    25081 actctgttgc cttgccagga ccaatacaaa ctgcttcatc tgccaacagc gtatgaagag
    25141 cttccttatc agcagttgaa taaaccgcta ccgtcgcaat ccccaattca cgtgccgcac
    25201 ggataatacg aaccgcaatt tcaccacgat tggcaattaa aatttttcga aacatggaga
    25261 acctccttag ttcccaattg caaaagtaag ggtaccactg gctgcaagct tgccatccac
    25321 ttcagccttt gcttcaacca cagctatggt gccacgacgt tttacaaaag tcgctgtcat
    25381 aaccaattgg tcgcctggta caacttgctt cttgaactta accttatcca taccagcgta
    25441 aaagaccagt tttcctttat tttcaggttt tgataactcc aacacaccag cagtttgcgc
    25501 caaggcttcc ataatcagaa cacctggcat aactgggtat tgaggaaagt ggccgttaaa
    25561 gaaaggctcg ttgatggtca catttttgat agcaacaatg gtatcctcgc tcacctccaa
    25621 gacacggtcc actagaagca taggataacg gtggggaagg gcttctttga ttccttgaat
    25681 atcgatcatt tgatacgtac caatccttta ccaaactcaa ccatttcttc gttagagacg
    25741 agaatttccg ttaccacacc atccttagga gctgggattt cattcatgac tttcatggct
    25801 tcgataatta ccaatgtttg accttttttg acactatcac caactgtaac gaaggcaggt
    25861 ttatctggtc cagcagccaa gtaaaccact ccaacaagtg gactctctac aagatttccc
    25921 tcactagcca cacttgcttc agctggagct ggaacttctt ctgctacagt ctctgctgga
    25981 gcagatgtag gagctactgg actcggtgtt gctagaacgg gtgctggagc gacttgagtt
    26041 gcaacttcag gcacaggtct cgcttcattc ttgctaaact gcaactcatc cgtcccattt
    26101 ttataagaaa attctctcaa acttgactgg tcaaattgag tcatcaagtc tttaatatcg
    26161 tttaaattca tacttatcta ttctcccaac gtttgaaagc aagaactgca ttgtggcctc
    26221 caaaaccaaa agtatttgaa atagcgtatg gaatttcttt ctccaagcct tgtccataaa
    26281 cgacattagc ttcgatataa tctgatactt cacttgtccc agctgtcatt ggtacaaagt
    26341 tatgacgcat agcttcgatg gtgacgatag cttctactgc acccgcagcc cccagcaaat
    26401 gtcctgtaaa agacttggtt gatgatacag gtacttcctt accaagaaca gctacgatag
    26461 caccactttc tcctttttca ttggcaggag ttgacgttcc gtgagcattg acataggcta
    26521 cttgctctgg agaaatctca gcttcttcca aggctagttt gatggccttg atagctccct
    26581 gaccttctgg atgtggagaa gtcatgtggt aggcatcaca agtatttccg taaccaacca
    26641 cttcagccag gatagtagct ccacgttttt cagcgtgttc aagactttct agaaccaaca
    26701 tccctgaacc ttcacccata acaaacccat tgcgatcctt atcaaatggg atcgaagcac
    26761 gagttggatc ctctgtagta gagagagctg ttaaggcttg gaaaccagcg atggcaaaag
    26821 gtgtgataga agcttctgtt cctcccacca acatcacatc ttggaaacca aacttaatgg
    26881 agcggaaggc atccccaatc gcatcatttg atgaagagca ggcagtattg atagatttac
    26941 aaacaccgtt tgcaccaaaa cgcatggcta cattcccaga agccatattt ggtaaagctt
    27001 ttggaagagt cattggtttg acacgtttgg gtcctttttc atgaaggcga agtacctgat
    27061 cttcaatttc cttgattcca ccaataccag atgcaacgat aacaccaaaa cgatccctat
    27121 taagagcctc tacatcaaga ttggcatgat ttacagcctc ttgggctgca tacaaggcat
    27181 ataaagaata gttatcaaaa cggttggtat ctttttttac aaagtattta tcgaacggaa
    27241 aatcttggat ttctgccgca ttatgcacat caaagtcact atgatcaaat tttgtaatgc
    27301 caccaatgcc gattttccca gttgctaaac tattccaaaa ttcttctggt gtatttccga
    27361 ttggagatgt tactccataa cctgttacca ctactcgatt tagtttcatt cttttcacct
    27421 ctagctttcg ctacatactt aagccaccat caatggcaat cacttgacca gttagataat
    27481 cttggcctgc taaaaatact gtcaaatctg caacctgctc tgcctgccca aattctttca
    27541 tcggaatctg agctagtgta gcttccttaa tcttatctga taagatagct gtcatatcag
    27601 actcaatcat tcctggagca atcacattga ctcgtatatt ccgactagcg acctcgcgtg
    27661 ccacagactt ggtaaagcca atcaagccag ccttagaagc agcatagtta gcttgaccaa
    27721 tattccccat caaaccaaca acactagaca tattaatgat agcaccttct ctggctttca
    27781 tcatcggttt caagactgat tgtgtcatat taaaggcacc agtcagattg accttgagca
    27841 ctttttcaaa atctgcttct gtcatcttga gcataagagt atcttgggta atccctgcat
    27901 tgttgaccaa aacatctact gaacccagtt ctgcaatagc ttgatcaatc atacgcttag
    27961 cgtctgcaaa atctgataca tctcctgaaa tgggaaccac cttgatacca tagtttgaaa
    28021 actcagcgag caattcttct gagattgccc cacgactgtt taagacaatg ttggctcctg
    28081 cttgagcaaa cttgtgggcg atggcaagac caattccacg actcgaacct gtaataaaga
    28141 tatttttatg ttctagtttc atttttttcc tttcaaaact tctacttatt ttagtctatt
    28201 tttctaaaag tgctactaaa ctcgcttgat cttccacatg agctaagtga gcagtttgat
    28261 caattttttt aacaaaacct gacaagactt tccccggtcc aatctcgata aagttgctta
    28321 tgcctgcttc ttgcatgacc ccaatacttt catagaaacg aacgggttcc ttgacctgac
    28381 gcgtcaagag ctgagcaatg tcctcttttt gcatcacagc agcttctgta ttgccgacta
    28441 ggggacaagt aaaatctgaa aaacttacct gagctagagt ttcagctagt ttctggctag
    28501 caggctcaag gagagcggtg tgaaagggac ctgacacctt aagaggaatc aagcgtttgg
    28561 cacctgcttc ttgcaaaagt tcaaccgctc gatcaactgc aaccacttct ccagcaatga
    28621 cgatttgtgc aggtgtgtta tagttggctg gagtaaccac tccaagttca gaagcttttt
    28681 gacaggcttc ttcaatgacc tctactggcg tattgagaac tgctaccatc ttgccagagt
    28741 cagcaggagc cgcttcttcc atataggctc cacgcttagc taccaaggca accgcatctt
    28801 caaaatccaa ggcgccgctt gccaccaagg cagagtattc tccaagagac aaaccagcaa
    28861 ccatatcagg ctgatagccc ttttcttgca ataaacggta gatagcaacc gaagtcgcta
    28921 gaatggctgg ttgcgtatag cgggtctgat tgagtttgtc ttcttccgta tcgatgagat
    28981 aacgtaaatc ataaccgagc acctgactcg ctcgatcaat cgtttcttta acaatcggat
    29041 actgatcata gaaatcccgt cccatcccta gatactgggc accttgacca gcaaataaaa
    29101 aggctgtttt agtcatttct tacaactcct gcccagcgag aggcttcttc ttgaattttc
    29161 ttagcggctc cgtaatacaa atcttttagg atttcttcag ctgtttcttc tttagaaaca
    29221 agccctgcga tttgacctgc catgacagag ccaccctcca catcaccgtg aacaactgct
    29281 ttggctaggg cacctgctcc catttgttca aagatttcta aatcaggatc ttcctgctta
    29341 aaggcatctt tttcagccag ttcaaaatct ctagtcaact gatttttaat agcacgaaca
    29401 gcatgaccaa agtgctgagc tgaaatcgta gtatcaatat cccttgcttt taaaattttc
    29461 tctttgtagt ttggatgggc attcgactct tttgcaacta caaaccgtgt ccccacctgt
    29521 acagcctctg cacctagcat aaagccagcc gcagcacctt caccatccgc aattcctcct
    29581 gcagcaataa caggaataga tatagctgtg gctacctgtc gcaccaaggt catggttgtt
    29641 aatttaccga tatgcccccc agcttccatt ccttctgcaa taacagcgtc tgcaccgatt
    29701 ttttccatgc gtttagctaa agcgacacta ggaacaacag gaataacgat tatcccagct
    29761 tcatggaaac gttccatata cttgcttgga tttcctgctc ctgttgtgac aactttaaca
    29821 ccttcttcaa taacgagatc cacgatatct tccacaaagg gagataagag catgatgttg
    29881 accccaaagg gtttatcagt caatgatttg attttatcaa tattggcctt gacaacttct
    29941 ttcggggcat ttcccccacc gataattcct aatcctccag ccttggaaac agcccctgcc
    30001 aaatcaccat cagcaaccca ggccatccct ccttggaaaa taggatagtc aatcttcaat
    30061 aattctgtaa tacgcgtttt catagtgcct ccaaccttcc ttgcttacgt aatagttcga
    30121 tttcaccata atttgacagt caaactatta cctaaacaag agggagtggg tttctcccta
    30181 ctccttctac taatattctg cttattttgc ttgctcttca acgtaagcaa ccaagtcacc
    30241 aactgttttc aagtcatttt ctgcttcgat ttggatatca aaagcatctt cgatttctga
    30301 gattacttgg aacaagtcca atgaatctgc gtccaaatca tcaaaagttg attcaagtgt
    30361 tacttctgat gcgtcttttc caagttcttc aacgataatt tcttgtactt tttcaaatac
    30421 tgccatgata ggactccttt aaaataaata gtttttttat aacaatgtgt tcaccacatg
    30481 attacctaaa ttgtaagaat gagcgtgccc caggtcaagc ctccaccgaa gcctgataga
    30541 agaacagttt ggctaccatc taaagggatg agaccttgtt ctacacactc tgaaagtaaa
    30601 atcgggatac tggctgcact ggtattgcca tattccatca tattagctgg aagtttggct
    30661 cggtcaacac caatttttct agccatctta tccaaaatac ggttattggc ttgatgaagt
    30721 agcagataat ccaagtctgt cacctctata ggagattcat caatagtctg cttgatagac
    30781 ttggctacat ctcgaatggc aaaatcaaag actgtgcgtc catccatctt caaaaatgaa
    30841 tctgcacttt cttgatctga aaatggagaa tgcaaacctg aatgcccata agttaaacac
    30901 tcgctgcgac ttccatcgct attgagactc tcagctaaga aatgctcttg ctcgctagct
    30961 tctaacaaga caccaccagc accatctcca aacaacacag ctgttgatcg atccgaccaa
    31021 tcgactgcct tagagagggt ttcactacca atcaccaagc ctttttgaaa gcgaccagaa
    31081 gcgataaact tttcagcagt tgaaagagca aatacaaatc cactgcaagc cgcggttaag
    31141 tcaaaagcaa aggctttatt agcaccaata ttagcttgaa cacgagcagc tgtagagggc
    31201 atcatcgaat ctggagtaat ggtagctagg atgataaaat ccagttcttc tcctgttatt
    31261 ccagcttttg ccatcagttt cttagcaacc tctgtagcca aatcactggt agattctgtt
    31321 cttgaaatat gcctttgtcg tattcccgtt cgacttgaaa tccactcatc attggtatcc
    31381 ataatctgag ccaagtcgtg atttgtaacc acttgctctg gcacataatg agcaacctga
    31441 cttatttttg caaaagccat tatttcaaat cctccaaaaa ttggtaaaga ttagtcaaac
    31501 ctttacccat gacagcaatt tcttcctcgc tcatgccatc aataattttt tctaccatgg
    31561 ccttgtggaa gcgtttatgc agtctatgaa tcaagcgacc cttctttgtc aaatgcagat
    31621 gcaccacacg acgatcctgt tctgaccgaa ctcgctcaat gtagccctta cgctctaaat
    31681 tgttcaaact tgtcgtaaca gttccaagag ttaccatcaa ctcttttgac acttgacttg
    31741 gagtcacatc tggagcctta ccgatgacat caatcgtatg catttctttg atggagatat
    31801 ccttaaaacg actacctctc aagttcactt cctcaattac aaggacattg ttaaatatag
    31861 atgttaaata ttcattgatt cgttggtagt ccatttttca tatccctcct tcttcaaaaa
    31921 acttttacaa tcaaaacatt tgacagaaag aattatatca aaattcaaag aatgatgcaa
    31981 gtatttttta ttttcctgta aatttaggtc ttcttctctc cgaatgagct cgcactcctt
    32041 ctttgaaatc ctctgtttga gctaaggatt tctgtaggtt cagttctaaa gtagcgtaac
    32101 cctgccagtc tttaaattgg ctctcccaaa ccaacttctt aatggcagca taggaattac
    32161 ttgaagcacg tcttaatttt ttaagaagct gttctctcgt cttttcaagt ttttcagctt
    32221 cagaaacgcg gtaaaccaac ccccattcta gggctttttc tgccgttaaa gcctctcctg
    32281 tcatagctaa ttgagcagca cgcgtcacac cgatactgcg gctcaagaga tgaattcccc
    32341 ctgcatctgg agccaaacca acaccaacaa aggcttggat aaacttagcc ttatccgtcg
    32401 ccaaacagaa atctgccgca acagccatat tcgctgcggc acctgcaaca gcaccgtcaa
    32461 cttccattaa aacaggtttg gctatttgct tgattttata agaaatcgta ttgaccaact
    32521 ctgcgatttt tgtcaatgat ggaatatcat cctcatccac tgcccgcttc atctctacca
    32581 aatctccccc aactgagaag acctttccat tggcattgat taagataaaa tgcacagctg
    32641 gattttcttc tgccaaagtc agagcttcta aaatctcctc acacatggga atatgaaaac
    32701 catttgcgac ctcaggacgg ttcaaggtaa ggattgccaa gtcctcttca agctgataaa
    32761 taatgtgttc catcagggct cctttttatt ttataagcag tttatactct tcgaaaatct
    32821 ctttaaaccg cgtcagcttc catctgcaac ctcaaaacag tattttgagc tgacttcgtc
    32881 tagcttctta gtttgctctt tgattttcat tgagtgttaa attatttcac tgtcaaagta
    32941 tatctttttt aggagcagaa agcaagaaaa aatcgactga aagtgtctca gccgataaga
    33001 aaggctcgct ttaggctaga aagcatctta ttttcttcat tgaaaaaagc ctttctttct
    33061 gctataatcg tataaaatac ttactttagg agttcttatg aaagttgtta aatttggagg
    33121 tagttctctt gcctctgcta gtcaattaga aaaagtttta aacatcgtca aaagcgattc
    33181 agagcgtcgt tttgtagtcg tttctgcgcc tggtaaacgc aatgctgaag atactaaggt
    33241 tacggatgcc ctgattaaat actaccgcga ctatgttgcg ggtaacgata ttagcaagag
    33301 ccaaagctgg attatcgacc gctatgctgc tatggttagt gaattgggac taaaaccagc
    33361 tgtgctagaa aaaatttcta aaagcattca cgccttggcc actcttccta ttgaagaaaa
    33421 tgaatttctc tacgatactt tcctagcagc cggtgaaaat aacaatgcca aattgattgc
    33481 tgcctacttt aaccaaaatg gtatcgatgc acgctatatg caccctagag aagctgggat
    33541 tgtggtcaca agtgaacctg gtcacgctcg catcattcca tcaagttatg acaagattga
    33601 agaattgaca aacaccaatg aagtccttgt cattcctggt ttctttggtg tcactaagga
    33661 aaatcaaatc tgtactttct cacgtggagg ttctgatatt acaggttcta tcattgctgc
    33721 tggtgtcaaa gctgacctct atgaaaactt tacggacgtt gatggtatct ttgcagccca
    33781 ccctggtatt atccaccaac cacactcgat tcctgagttg acctaccgtg aaatgcgcga
    33841 gttggcctat gcaggcttct cagtccttca tgacgaggct cttcttcctg cctaccgtgg
    33901 aaaaattcct ctggttatca agaataccaa caaccctgac catccaggta ctcgtatcgt
    33961 tctaaaacac agtaatgatg aatttccagt tgtgggaatt gctggtgact caggctttgt
    34021 cagcattaac atgtcgaaat acctcatgaa ccgtgaggtt ggatttggcc gcaaggttct
    34081 gcaaatcctg gaagaactta acatcggttg ggaacatatg ccaacaggta tcgacgatct
    34141 ttctatcatt ctccgttctc gccaactaac tcccatcaag gaagaagaaa tcctgcgtca
    34201 gttggttcaa aaggctaaag tagatcatgc agaaatcgaa cacgaccttt ctatcattat
    34261 gattgttggt gaaaaaatga agagccatat cggagtgact gctactgcga cacgcgctct
    34321 atctgaaaac aaaatcaaca tccagatgat gtctcaaggt tctagtgaag tttctattat
    34381 gtttgttgtc aataaagacc aagagaaagc agcaattaaa gccctctaca atgccttttt
    34441 tggagaaagt aaggaagact aagcatggcc caatcactta acaaaacagt actcctcagt
    34501 acgacaggca cttcctacct ctctatcgct gggaaagttg ggaaattcct tgtcggagat
    34561 caggctttgg aattttaccc agatgtcaat gtcgaacaat ttatccagat tccttggagc
    34621 catatcaatc agattggagc caatgtcact ggacgcaaaa tcagccgcca cttcgaagtc
    34681 tttacagaca aaggaaaatt cctctttgct tcaaaagact caggtgccat tctcaaaatt
    34741 gcacgcgaaa aactaggcaa tgacaaggtc gtcaaacttc cgaccctgat tcagacaatt
    34801 agccaaaaat ttaaaaatct atttgcaaaa aagtagaaac tttagtataa tcatagcaac
    34861 ggataagtag gttatcttct tctttcagaa agtctgcggg tactgcgagc agataggggg
    34921 gataggtgaa attctaccgt tagtaacaat tacatacaca atcaagtgca cacctgtgaa
    34981 gttggatgga accgtggccc tgccactcca acgttttgtc aggcgtgctt ttttcataaa
    35041 ggagttctta tgttagatat caaacgtatt cgtacagatt ttgaagctgt cgcagaaaaa
    35101 ttagctacac gtggtgtaga tgctgctgtc ttgaatgaaa tgaaagaaat cgatgctaaa
    35161 cgtcgtaaca tcttggtcaa ggttgaaact ctcaaagcag aacgtaacac agtttctgct
    35221 gagattgccc aagctaagcg caacaaggaa aatacagatg acaagattgc tgccatgcaa
    35281 aatctatctg ctgaggttaa agccttggat gctgaattgg cagaaatcga tgctaaattg
    35341 acagaattta caacgactct tccaaatatc ccagctgaca gcgttcctgt tgggactgac
    35401 gaagacgaca atgtggaagt tcgccgttgg ggtactccac gcgagtttga cttcgaacct
    35461 aaagctcact gggatctcgg tgaagacctt ggtatccttg actgggaacg cggtggtaag
    35521 gtaacaggcg ctcgcttcct cttctataaa ggcctcggtg ctcgtttgga acgtgctatc
    35581 tacaacttta tgttggatga acatggaaaa gaaggctata ctgaagtcat cacaccttac
    35641 atagtcaacc atgattctat gtttggtact ggtcagtatc caaaatttaa ggaagatact
    35701 tttgaactca gcgataccaa ctttgtcttg attccaactg ctgaagttcc tctgacaaac
    35761 tactaccgtg atgaaatctt agacggcaaa gatcttccaa tctacttcac tgccatgagt
    35821 ccgtcattcc gttctgaggc tggttctgcc ggtcgtgata cgcgtggctt gatccgtttg
    35881 caccaattcc acaaggttga aatggtcaaa tttgccaaac cagaagaatc ttacgaagaa
    35941 ttggaaaaaa tgacagccaa cgctgaaaac attcttcaaa aactcaacct tccataccgt
    36001 gtcgttgctc tctctactgg agatatgggc ttctcagctg cgaagactta cgacttggaa
    36061 gtgtggattc cagcacaaaa caattaccgt gaaatctcaa gctgttcaaa cacagaagat
    36121 ttccaagccc gtcgtgccca aatccgttac cgtgatgaag cagatggcaa ggtgaaactc
    36181 cttcatacct tgaacggctc tggacttgca gttggacgta cagtggctgc aattcttgaa
    36241 aattaccaaa atgaagatgg ttctgtgacc atcccagaag cacttcgtcc atacatgggt
    36301 ggagctgaag tcatcaaacc ataaaaaata aggtttagct atttctagct agaccttttt
    36361 tcgtaaccaa atcagataag cacctagtac aaagaataaa atagttaggc atataatggt
    36421 ttcagccaat accaggtaat ccagaaatgg aagtttcaaa attccctgag ccatcttgag
    36481 cgaggtcgct gtgataatgg ttgggaaggt gagggctgag aaggctggtt gaaaaccttg
    36541 ttttaaaatg ttgggcagac gagttaaaac aaagaaaaag aaggattgag aagccaaaat
    36601 catgacaatc aagacccaag tcggcaggct ggttcctcct actcgaacta gagaagccaa
    36661 gagtagagag aaaggagcac agtagattcc ttcttgtcca agcaaggcta gtgggagtgg
    36721 atgtttcttt aaatcgctat aaataagggg atagagatag aaggtcaaga gaaaaccaaa
    36781 actcaaggtc gcataggcaa tttcgataat acctaccaga ggataggtca aggcagccac
    36841 tgctatcccc acatagagaa ccgtccaact tggagtggca tgaaccctcc gccctgaaca
    36901 agcaaacttg atggtaaaac cagcaatcaa ggtcaaatcc aagagaaatg aaaaccacca
    36961 aatcccttgt gctaccaaag gaagataaga gaatacgcga aagacatagg tcgataaaat
    37021 catcccagcc ataggaaagg ttgccattcc tgacaaaaga gggggcttgg tcaattcttg
    37081 cttggtttct ttccaattaa agagatgcag aattagaaag taaatccata aaaccaaacc
    37141 agtcagacta aaaagatggg atagaaccgg caacgtatct aaaataagat ttccagctcc
    37201 tgccaaacct agcaaacaac ctgaaaatac taaggggagt tttttcatcc taacctccaa
    37261 taatcatgtt agtttcagta taacataaaa gcgcttaaat gaggatttaa aaaaacgaag
    37321 tccgcttatt tcagacttca ttttactcag atatgaatta ggcataaggt tgcaattctg
    37381 gattaattgg tgtattagct aagttgttgg catagttaca gaggattgct aggctgacac
    37441 caaaaaccac atccaaggca ttttgttgag tgtagccagc ttctaaaaac tcagacaagg
    37501 cttcatctcc tacacgaccc ttggtattga taactgccaa ggtaaactta gctagggtat
    37561 ccaatttagg atctgtttca attggagtac gattgcgaag agcttgaatc aagtcatcat
    37621 tcatctggat ttgtttgatg gaaaaggctg tgtgacctgc gacacagaag gcacaaccat
    37681 tggtcacggc tgccgtgatt tgcaccactt cacgctcaac gggtgtcagg ctgttgcgac
    37741 ggtggataga tgagacaatt tggtaggctt ctaaaacagt cggggcattg gccaagagac
    37801 cgattaggtt gggaatatag ccattgttgt ctttttctac tgtttcaaga atttctttca
    37861 cttctgctgg tgctgactct actgtatgga tagtaaatgt tgtcataaga tacctctttt
    37921 cttattattg acactaatat tattggaaaa tcttataaaa tcctgattcc taagtttatc
    37981 taagataaag ctttattctc tcataagatt ttcgttgtta tattagttta tcacacttcc
    38041 aatcacttgc ataatatata ttatatatca ggctgataaa aattatttat aggcaaaaaa
    38101 atcacacgag ctgtgtgatt ccattatttg tcaaaatact ttttagtttc agcaataacg
    38161 actggcgaca agaccaagag ggcaatcaag tttggcagag ccatcaaggc gttaacgata
    38221 tctgcgataa tccagaccat atccaactcg ataaatcctc ctaacaagac catgagcaca
    38281 aaaaacacac ggtagagcca gataaagcga gccccaaaga ggaactcaaa acagcgttct
    38341 ccgtaatagt tccaacctag aatcgttgta aaggcaaaaa gtacaaggaa gatggtcaag
    38401 agggcaggcc caaagtgtga aaagactgtt gagaaagctg actgagtcaa ggcaacccca
    38461 ttcaagtcac cactccaaac tccagttacc aagatggtca aaccagttag agtacaaatg
    38521 atgagggtat caataaaggt tcctgtcatg gaaatcaaac cttgctctac tggttcattt
    38581 gtcttggcag ctgcagctgc aataggagca gaacccagac cagattcgtt tgagaacaca
    38641 ccacgcgcca caccattttg aatagccatc cgaacgctag caccagcaaa tccacctacc
    38701 gcagcaaggg gactaaaagc tgaggtaaag actaaagcga ttgtgccagg gatttttccg
    38761 atattaaaga aaataactgt aagagttcct aagatataaa tgagggccat aaaaggaaca
    38821 acagtagttg aaaccttaga aatagacttg agtccaccaa agactgcaat cgctacaaag
    38881 acagacaaga cgagagctgt gatggctggc gaaatcgtcg ttgtattttg gatagattct
    38941 gtaatcgagt tgacttgggt gaaggttccg attcccaaga gagcaaccaa tactcctgct
    39001 actgcaaaca aaacagcaag tggtcgccac ttttctccca tccctagaag gatatagtgc
    39061 atgggacctc ccgctactgc accatggtcg tccttggtgc ggtatttgat ggccaagagt
    39121 ccttccgcat acttggtagc cattccaaag aaagccgcca tccacatcca aaatagagct
    39181 cctggtccac caaccttgat agccgtcgca actcctatga tatttcctgt tccaacagtt
    39241 gatgccaagg ctgtacacag agctgcaaaa ctggatacat caccatgtcc cttatcctgg
    39301 ataaaaataa gctgaaaggc cttgggcaga cgcaaaacct gcaagagtcc tagccgcatg
    39361 gttaggtaaa tccctgttcc gaccaataaa atcaagaggg gcggtcccca agcaaaagca
    39421 tcgattgatt taagcaattc taacatttcc ttctcctatc gtttcaaccc caaaagaaag
    39481 agcacatgca agatacatgt actctggaat gcttagataa atgctaaaaa gcggtctatc
    39541 ctagctctgt ccttttacct gagagtttga gcagttgcct gccttgcccc ttcggtgcct
    39601 ttacggtctc tccagagttc cgtccattta cagtcatgga aaatcaaacg attccccact
    39661 tctattaaac ttcattcggt gttggtattt aattgattct aattttacaa aaaatgttgg
    39721 cttttgtcaa tgtgtttatt agtaaaaatt agttcaacag tttttacttt ataaagtcca
    39781 gaatactgct atcctttaaa agtgacaata gtcgcaccac tgcctccagc attttgtggg
    39841 gcatagccga aactcttgac atgtttgttt ctttgcaagt atttggtaac tccttcacgg
    39901 atgactcctg ttccgatacc atggatgata tcaacttgag ccatattgtt aagcaaggct
    39961 tggtcgatga aggtatctag ctcattcatg gcttcttcat agcgcttgcc tcgaagatcc
    40021 agtctagctt gaggtcctcg cccagaagtt cgtttcacaa cattgacctg tttcttcttg
    40081 actggttttt cttgctgggc ttgaacaaga tcaaactctt tctcttccaa ggtcatctta
    40141 atcaagccaa cttgggcttc ccagcgaccg tccttgagtt gactggtcaa ggtaccacgc
    40201 tgaccataac tgagaaccac gatatcatct cccacctttg gagctcgttt tttcttggcc
    40261 ttttgaagga ccttattttt agacaagtcc actttttcag gagccaattt tttcaacttg
    40321 gccttggctt caatgatttc gtggggcttg agttgggatt tactgtggag atttttgaga
    40381 atctggtcac tttcacttag ggccatatcc acaatctcag cagcctgttc acgcgccttg
    40441 ttaagctcgg tttccttttc acgattaagc tcgttgtaga gtttttttag cgcacggttc
    40501 atcttgagat tttcttgctc cacctcacgg atattgtcca aacgtttgcg gctttccagc
    40561 gtctgctctt ctaattgctc aatgatacga ttgacgtcat tgtcctgatc gatctgctga
    40621 ctggcatctc ctacgataac ttcagatagg cctagacgtt tggcaatttc aaaggcatta
    40681 cttcggccag gaacaccctg cataaagcga taggtcgggc gaagagttgc agtatcaaac
    40741 tccatactgg cattttgcac aaaggctgtc tcaataccgt aggccttgag ttctggatag
    40801 tgggtcgtcg ccatggtctt gatttgacgc aggcgaaggt cctccagaat agccatggca
    40861 agggctgctc cctcttgggg atcagtacca gcccccaact catccaaaag taagagtgaa
    40921 tgttggttga ccttgccaag aatatccacg atattggtca tatggctaga gaaggtagac
    40981 aagctctgct caatagactg ctcatctcca atatcagcaa agatttcttc aaaaatacca
    41041 acacgacttc ccttgtctgc taaaatcggc aatcctgact gggccatgac ctgtgtcaag
    41101 cccagagttt tgagcatgat ggtcttccca cctgtattgg gacctgtaat gacaatagct
    41161 gttaaatctt gaccaaaatg gacatcattt gcgacggcat ttttgaccaa aggatggcag
    41221 acatggagca gttgaatctc ttgattttct gacagctgag gcacgactgc ttgtctttct
    41281 tggataaatc gaaccttggc acgaatcaag tccagatgac cgataatcca agcgtcatta
    41341 gcaatctcag ccgcatgagg gcggacacgc tcagaaattt cttggagaat gcgaagcatt
    41401 tcatagcgct catctgctcg cagactagca atttcttcgc tcagtttgac tacctcacgt
    41461 ggttcgatat agacggtgtt tccactagca gaaatatcat gaacgacacc tgcaatctta
    41521 ttgcggtagg tgtttttgac tggtaaaacc tgacggccat ttctgctagc aacaattcct
    41581 tccgtcaaca tctgcgcttt ttgcttgagc aagtcttgta aaacatcgcg tacctgactc
    41641 tcgctatcat gtatttttcg acggattcgc gccaattctt cactggcaaa attttcaatg
    41701 aaacccgcat cattaaaggc ctgaagattt ccttgtaatt gcggaaaatc atgtaatttc
    41761 tcaaaccaaa gggctaattc ttccaagctg acattttcca gattggcata aaaactttga
    41821 agttctcggc tggcaagaag cacgcgtttc aagagtagga actcctcgat attgagatcc
    41881 gctcccatct ccaacctctt gcagactcct gcaatttcct tagttgagag aatagtaaaa
    41941 tgcggttgct cgacgaaaag agcctgcatt tctttcatct cagcaaaagc ctgtttgatt
    42001 ttatctgctt tggcagtcgg agccagctgt ctcaattgct ccaagccctg ctcggtcaac
    42061 aaatgaggat caaacaaggc cttgacctta tcgaactcta atgtttctaa tattttctta
    42121 ttcatcttta tttccttgtc tttgaatgtc taggtgtggt agctttttac attctgatag
    42181 attcgagtca aatctgtaaa caaagggcta ggaaaactcc tgcccttttt atccgattaa
    42241 atttgtcacc cagatttgtt tgagccaact ggttgttatc ggtatgctct ggatgatgtg
    42301 ttttgcgacg atactctttt caagaggatt ttgtataact gccatgggga tggtcgccaa
    42361 gattgtcaag gccatttgca agacaaataa ggtcaccaac atggacaaga tacctgctga
    42421 aacttggaac aacttaccac ccagtttttt gctaggaatc aagtgtaaga gaagaccaag
    42481 caaacgacca atgctataga aaatcccaaa tacaagcaag tagccgatac ctgcataaaa
    42541 gaccttatcc agctgaaaga gttgatccga tgggaaaaag aaagtcccct gaccttcctg
    42601 cgaatttgca taagggagca ataaatggaa ttgctctcca agccccttat aaaactggcc
    42661 agccataaaa gccgatgcca tggctgaaat caggtaataa acctgtaaga gcaggcctct
    42721 ccgatagccg atataaaatc cccaaaccaa gaccaataga agaaggaatg aaatcataag
    42781 gaatcctcaa tcttgctctg ttcttgctta caagtcacaa gcttgtgacg gagttcttct
    42841 agctcttgct ccttatcgtc aaattcaatc tcacggctga gctgagttga taaacagttg
    42901 actgccaaca aaagagcgat tgtttcatca tctgcgctag gcatttgttc tttaattgct
    42961 tggtattttt ctgtcgcaac cttagcgatt tcctccataa aaaggttatc atgttcgctt
    43021 gtcaaggtta acgatttttt cccgaatgta aatttgaatc gatttagatt tgccataaaa
    43081 ttcacctcac gatattatac caaaattcgc taattttgtc agtttttaca aattttactg
    43141 cttttgtggt acaatagaaa ctatggcaag tatcacactc acaccaagcg aaaaggatat
    43201 tcaggctttt cttgaacact atcaaaccag tctggctccc agtaagaatc cctatatccg
    43261 ctactttttg aaactacctc aagcaacggt ttctatctat acttctggaa aaatcttgct
    43321 tcagggtgaa ggggctgaga aatacgctag tttctttggc tatcaacttg tagaggaaaa
    43381 cagggggcaa aatcttcctt taattgggac agatgaggtg ggaaatggtt cctactttgg
    43441 tgggcttgca gttgtggctg cctttgtcac atctgaccag cacgactttt tacgaaaact
    43501 cggtgtgggg gattctaaga ctctgaccga ccaaaagatc cgtcagattg ctcctattct
    43561 caaggaaaaa atccagcacc aggcactcct tctctcaccc agcaagtaca acgaggtcat
    43621 cggagaccgc tacaatgctg tttcggttaa ggttgccctc cataatcagg ctatctatct
    43681 cctccttcaa aaaggtgttc agcctgagaa aattgtgatt gatgccttta ccagtgctaa
    43741 aaattatgac aagtacttgg cacaagaggc caatcgtttc agcaatccta tcagcttaga
    43801 agaaaaggct gagggcaaat acttgtctgt cgcagtttct tctgtcattg cgcgtgatct
    43861 ctttctggaa aatcttgaaa atttgggacg agaactgggt tatcagctcc caagtggagc
    43921 tggaacggct tctgacaagg tggctagcca gattttgcaa gcctatggta tgcagggact
    43981 cagcttctgc gccaaattgc actttaaaaa cactgaaaaa gcgaaaaaac gcttagaaag
    44041 gtaagttatg aattcattta aaaatttctt aaaagagtgg ggattgttcc tcctaattct
    44101 gtcattacta gctttaagtc gtatcttttt ttggagcaat gttcgcgtag aaggacattc
    44161 catggatccg accctagcgg atggcgaaat tctcttcgtt gtaaaacacc ttcctattga
    44221 ccgttttgat atcgtggtgg cccatgagga agatggcaat aaggacatcg tcaagcgcgt
    44281 gattggaatg cctggcgaca ccattcgtta cgaaaatgat aaactctaca tcaatgacaa
    44341 agaaacggac gagccttatc tagcagacta tatcaaacgc ttcaaggatg acaaactcca
    44401 aagcacctac tcaggcaagg gctttgaagg aaataaagga actttcttta gaagtatcgc
    44461 tcaaaaagcc caagccttca cagttgatgt caactacaac accaacttta gctttactgt
    44521 tccagaagga gaataccttc tcctcggaga tgaccgcttg gtttcgagcg acagccgcca
    44581 cgtaggtacc ttcaaagcaa aagatatcac aggggaagct aaattccgct tctggccaat
    44641 cacccgtatc ggaacatttt aagagaccta agaggccgag aatcaccaat ctcagcctct
    44701 tcttctatcg tgagaagtga ttgtttattg acaaatactc aacgaaaatc aaagaacaaa
    44761 ctaggaagct agccgtaggc tgcttaaaac agtgttttga ggttgtggat agaactgacg
    44821 aagtcagctc aaaatactgt tttgaggttg cagatggaag ctgacgtggt ttgaagatat
    44881 tttcgaagag tataaaataa aaacaatccc aactctcacc tattcatgca aaggaatttt
    44941 atggaagttt atttttcagg aaccattgaa cggattattt ttgaaaatcc cagcaatttt
    45001 tatcgcatcc tcctcctaga aatcgacgat acggacgcag aggattttga tgattttgaa
    45061 atcattgtca caggaaccat ggctgatgta attgagggcg aagactatac tttttggggg
    45121 caaattgtcc agcactccaa gtatggagaa caactgcaaa tcagtcgtta tgatcgcgca
    45181 aaaccaacta gtaagggctt ggtcaagtac ttttcaagta gccatttcaa ggggattggt
    45241 ctcaagacag ctcagaaaat cgtggatacc tatggcgaaa ataccattga cgaaattttg
    45301 caacacccag aaaagttaga aggcatcgca ggactctctg ccaaaaatcg cgaggctttc
    45361 gtctccactc tccgtctcaa ctacggaacg gagatggttt tgtccaaact agccaactac
    45421 ggcattccca acaaactagc ctttcagatt caagactttt acaaggaaga aacccttgat
    45481 gtggttgaaa attatcccta ccagctggtt gaggatatca agggtttggg ctttaccatt
    45541 gctgaccaac tagctgagga actaggcatc gaaagtcagg ctcctgaacg cttccgcgcc
    45601 ggtctagttc acagtctttt tcaggcctgt atggaaacag gggacaccta tgttgaagca
    45661 cgggatttgc tggaacaaac ccttactctc cttgagtctt cccgtcccgt ggaactagac
    45721 cccagccaag ttgcccaaga gctctcctac ctgatcgaag aagacaaggt tcagcagatt
    45781 gataccaaga tctttgacaa cagcctcttt ttcgctgagg aaggcatccg cagtcacttg
    45841 gttcgtatcc ttgaaaaagg aaaacagaag agtcatgatt tagaaaccat tcaaaaacat
    45901 atcactacta tcgaggaaga gctgggaatt gagtatgata acattcaaaa acaggctatc
    45961 tgtgatgcta tccagaataa ggtctttatc ctgacaggtg ggcctggtac tggtaagaca
    46021 actgttatca atggaatcat cgctgtttat gccctgttag agggacttga cttcaggaag
    46081 aaaagcaatc tgcctattct tcttgctgct ccaactggtc gagctgctcg tcgcatgaat
    46141 gaattgacag gtttgcctag cgcgaccata catcgccact tgggaatgac aggtgacgat
    46201 gataccagtc atctggaaga ttacctagat gctgacttta tcatcgtgga tgaattctct
    46261 atggtagata cttggctggc caatcaactc ttctccaata tctcttctaa cagtaagatc
    46321 ctcatcgtag gtgacagtga tcagctacct tctgtcagtc ctggacaggt tctagcggat
    46381 ctgcttcata ttcctttgat tcctcagact cacttggaaa aaatttatcg acaaagcaaa
    46441 gaatcaacca tcgtcaccct agctagtcag attcgacagg gcatcttgcc agctgatttc
    46501 acccaaaaaa aagctgaccg ttcctacttt gaaattgcta gtggccatat tcctgccacc
    46561 attgaaaaaa tcttaggtgc cgccctcaga aatggtattc ctgcccgtga tatccaagtt
    46621 ctggctccta tgtaccgagg gacggcaggg attgatgcta tcaatcagct catgcaagac
    46681 ctgctcaatc ccccacaaaa agatcaactc agttttgaag ctcctcagtg ccactatcgt
    46741 aagggagaca aggtcattca tttggttaac gatgctgaaa tcaatgtctt taatggggat
    46801 ttaggagcta tcacagacct gattcctggt aaatacaccg aatcgaaaca agacgagatt
    46861 gtcattgatt ttgatggtaa tgaagtctct tacccccgta acgaatggta caagattcgc
    46921 ttggcctatg ccatgagtat tcataagtct cagggaagtg agttcccagt tgtcatccta
    46981 ccgattacta gtgctagccg acgtatgctg gagcgaaatc tcatctacac agccattaca
    47041 cgtgccaaaa gcaaactcat cttactaggc gaattacaag ccttcgacta tgctacccaa
    47101 cacatcggaa ctgcccgaaa aacctatctg attgaacgct tcagtgatct actggagaat
    47161 gttgaagaaa agcaacaagc tgtctctgaa acagtcacat caagtgcctc tgaacaatcc
    47221 tacatcctaa ccgaagaaaa ctgggacagc attccagcca tgattgggat tacagacaca
    47281 gacctcaaag agatttttgg aaaatagtgc atcagaaaaa ccaccaattc aggtgggttt
    47341 tctgtttatt aagattattt tactgttgct gtgcttgtaa tcaattcaac agcttttttg
    47401 atagtgatat catgtttcaa catgtcagct gaaagcaagt tttgaacttg tgcaacttcc
    47461 atgttgtagt ctgctgccaa ttgctcaact tctttttgga tttcttcttc tgaagcatca
    47521 aatccttcag ctttggcaac tgcttcgata acaaggttag tcttagtacg tgactcagct
    47581 tctgcttggt attggttgtg aaggtcttct tgagtagttc cagtaatttg gaagtacatg
    47641 tcagggttga tcccttgacg ttgcaagttc ccaaggaatt catttactga acggtgaact
    47701 tcttcgtgga tcatttcttc tggaagttct acgatttcag cattttctac agctgtatca
    47761 attgctgcac cttcaactgc atctttgtaa gcttcttctt tagcagcagc caattctttg
    47821 cggtattttt ctttcaagtc agcaagtgtt tcaacttctt catcaatgtc ttttgcaagt
    47881 tcatcgtcaa gagctggaac ttctttagct tttacttcgt ggatagttgt cacgaattta
    47941 gcttctttac ctgcaaggtc ttctgcttgg tagtcttctg ggaatgttac gataacatca
    48001 acggtttcgc cagctgagtg acctaccaat tggtcttcga aaccagggat gaattgacct
    48061 gaaccaagtc caagtgagaa gttttcacct tttccaccgt caaattcaac accgtcgata
    48121 gaaccaacga agtcgatcac aacagtgtcg ccgtcttcag cagcagcttc cttgataacc
    48181 aattcagcca ggttgttgcg ttcacgttcg atacgctctt cgacatcagc gtcagttact
    48241 tctttttcta catcaactga tacttcaagg tttttgtagt cacccaattt tacttcaggt
    48301 tttgtaacaa cttcagcagc gataacccag tcttgacctt tttccattga agttacgtca
    48361 atttttggtt gggcaaccac ttcaagacca gcctctttta cagctgcttc ataagcgttt
    48421 ggcaaaagag cgttcataac gtcttggtaa agtgattctt caccaaattt tttatcgaag
    48481 ataggacgtg gaaggtgacc tttacggaaa cctggaacat taagagattt cttcactgac
    48541 ttgaagacac ggtccaattc tggtttgatt tggtcttgag agatagtgaa agtcaagaca
    48601 ccacggtttg tttctttgtt ttcaaatgat acagacattc tgtcatttct ccttaaaatt
    48661 ttttaaatac agtctattat aacattttct ataaataaaa tctagactaa tgcagacaat
    48721 tatagacaac aagccttttt cctaactaaa acactcataa agtatagaca attttagact
    48781 actttggata tcttttggtt agtcattttc caaaactaat ttatctaatt tttaagttat
    48841 atttgacttc atcttctcag taacatgagt ataaacactt aaaatctttg tttcattagt
    48901 ataatctaca cgatccatta tcgctgttat aggtacttcc aattcagcaa gcaaacttat
    48961 atgcgaatat ctaaaaacat gagcagtcaa tacaaaatca tctttcttaa tttcactttt
    49021 cctaaacctg tttttcaaaa agtaattgaa acaagttatc attaagggag aaccattatt
    49081 tgtaaatata taatcacctt cttctaaaag aagatattct tttaaaattt ctaacactct
    49141 atcactaata ccaattactc tatatgaagc taaacttttc ggactatcca aaaacacttc
    49201 gttattggac gattacatta tagtaaaacg aaataagaac aggacaaatc gatcaggaca
    49261 gtcaaatcaa tttctaacaa tgttttagaa gtagaggtgt actattatag tttcaatcta
    49321 ctatacaaga cgaaattgaa gaaatctttc cattataaaa cgcatattat caaggttttt
    49381 aaacacctaa taatatgcgt tttttcctat tttaaagact tttatccacc tattatacaa
    49441 agttaagtat ccatcacagt ttacaattag ccttcattac ctaacccatt caccatcctt
    49501 caagagagta acctttaaga accgaataaa taaatggcaa atttcgttca tttaatttaa
    49561 ctgcactgtt aatttgatta gctccatctc ctaaagtatg cactcctact acacggtgac
    49621 tagcatcata aactgtagat ccactagacc cctctaaagt atcaacttgg taatccaaga
    49681 acatgccatc atcacttaaa acttgttttt tatctgtata catttgatga actttaaaat
    49741 tatatgatgg atagcctgtg atagtcacag ttattcctgt caaatttttt tgactagtag
    49801 gaagacccaa agtccctaat tttgcaccaa tgggctcttc tagaattaat aaagccaagt
    49861 catattccct tgcatcctta gaatttaaat ttctaaattc cttcaaataa cgaacttcct
    49921 ttactttgat ctttccaaat ggttcttgac ttggactaac agtcggaaga acataaatat
    49981 catccgcttc tttcccatag tcatgtctgt agtagttgtg agccgctgta attaacacat
    50041 tatctttaat aaaattcgca cttcccctcc cttctacatt cattccatcg gctactccat
    50101 aatacttaga taaaaccata gctgaagtcg aatacggata ctgtaaagta ttatcaattt
    50161 taatcaaatc atcattaccg ataatacttc tgattgcttt tggtagtatg aaccatatgt
    50221 tggtgaaatc tcagataatg aagaatcatt agatcctgga cctttttcta gtgtctcact
    50281 tacctcatat tcttcacccg tactagaaat aacactcaaa gcagatactg tcgataactg
    50341 gctagccaat aaagtactcg caataattga aatacccaat tttttataaa cagttttctt
    50401 cattattgta tcctcctaat gtaattatag cgtactattc taaatttctt aatctactat
    50461 agaatcaaga aatctaccac cttctttaaa taccctccat tatcacataa acaggtaaac
    50521 ttttcaatta atgactgcgc ttttcaatca cgctagaggt acttacttgc ttctttgata
    50581 ctaagttcag ccattctttc cttgtttttc tcaataaagc atgttaccca agtgggattc
    50641 gttttggagt agtctcgcag agtccagcca atggctttat tgataaaaaa ttctgtttgg
    50701 ttcaagttat gaagtagaat cttttccatt aattgagtat tggtcttctc ttttcttaac
    50761 aactggtggt caatagcgac acgtctcagc cagatattat ctgataggct ccattttata
    50821 ctcaatgaaa atcaaagagc aaactaggaa gctatctgca acctcaaaac actgttttga
    50881 ggttgcagat agagctgacg tggtttgaag agattttcga agagtattaa gattatttct
    50941 tctagttcag ggtgttcata caccaaactc cctactactc gatctaggat atctaccgtg
    51001 tcccaccagg attttgtcac gactaactgc tctagcttag gcaaatcggt ttcctttaga
    51061 taagactgca ttgctttcaa atagttagca gccacatatt ggtattttct aggctccttt
    51121 tcccagcaag tgtctgcaaa atcccaatcg ataatctttg tttttttcgc ttctggtaaa
    51181 tatttttata gagtttattt ctttcaggca ccgcaatacc tagaaaagaa aattgatggc
    51241 gcatataggc ttccatgggc cttgcttttt tagagtcttt tgctgcttct agctcctcaa
    51301 gtaaatctgc taaactcatc taaaactcct cttgccccac caaatggtgc tgaaaggcat
    51361 agacagccgc ctgggtacga tcgctgactt caagtttggc aagaatattg gacacgtggg
    51421 tcttgaccgt cttgagagag ataaagaggt catctgcgat gcgctgattt tcgtagccct
    51481 tggcgatgag ttggagaaca tctcgctcac gcgcagtcaa ttcttcatga agttccatat
    51541 gattgcggtg gtattcaacc ttcttgctaa cctcttgctc aatggccagc tcgccagcag
    51601 ctaccttact gacggcatga agcaattcat ctgcactaga agtcttgagc atatagcctt
    51661 tggcaccagc atctaagact ggcatgattt tttcattgtc caaataagag gtcacaatca
    51721 aaatcttggc ttcaggccat tctttaagga ttgctaaggt cgcgtcaatc ccattcatct
    51781 caggcatgac aatatccatg acaatgacat ctggacgcag ttccaaggcc aagtcaatcc
    51841 cttgagaccc gttggacgcc tcacccacaa cttctacatc gtcttggagg tcaaagtagc
    51901 ttttcaagcc caaacggacc atttcatggt catctactag taaaattttc atctttactc
    51961 ctttatcatt ccttatctaa caggggaata cggatatcaa ctgccagccc ttgcttggga
    52021 gctgttaata actgaaccgt ccctgccata tcttcaaccc gctccttgat atttcgcagt
    52081 ccataactca agtcgtctaa gcttcctaac cggaaaccaa tcccattgtc caccaccttc
    52141 agttgcaatt caacatctgt ctgatagagg tagacatcta ggcaagatgc ctgggcatgg
    52201 cggagggtat tgctaatcaa ctcttgcagg atacggaaga tatgctcctc gattttctta
    52261 ggcaatttcg tcatattctg cttgagacta accctaagat cactcttgtc ctcaagctct
    52321 tttaagagaa tctgaatccc ttctatcaag ctcttctgct ccagttcaac tggtcgcaaa
    52381 tgcaagagca aaacccgcaa atccttctgg gcagtttcta aaatagctgt gacactctgc
    52441 aactgggtct gcatcttttc tctatccaat ttcaaagcct gctgactgat acccgataaa
    52501 ataatgtggg ccgcaaacaa ctcctgactg actgtatcgt gcaaatcccg agcaattcgc
    52561 ttccgttcct tctcgataat ttcctcttcc tgatcaaggc tatgattttc agctttttga
    52621 agagcctctg tcaaaaggtt aagtttacct gataaggact tgaaactggc atccaaatct
    52681 ggatctacaa cctgaactac ttcttgccct gccaataaac gcttgagatt agcctgcatt
    52741 tttcttagag aaagctcttc gatccctcgc caaaacaggg ctaagagaca ggtcatggac
    52801 atgctgaaaa ccaacaataa aaagacaaat ttttctgttt tttcgacatc gtacaaaaag
    52861 atagaccagt caaaatcaag tatttccagc aagctgtggg agaaaaaaaa gacaaatagg
    52921 aaggaggtga gagcaataat gacataggct tgttttttca tcctctaacc acctccacat
    52981 caccaatcat agtggtcaag aaaatcttga cactcttgtt actcttgaga tagtcttttg
    53041 tttcttgatg atagtgttca ttgcggaggg ctcgcttggg ctggttgaaa aaagtcaaat
    53101 ccccatagag acagttaacg ctgagactga cttccacatc tacaggtacg atgattttgg
    53161 tcgttcctac catctttctg aggataatga cattgtcatg attggttaag atgactctct
    53221 ccagatgaat agtgtccttg cccatgaagc gaaagagatt gatatcatca aattggcaag
    53281 tctggtagct tgaaaaatga tgaagatttc caaaccaacg atttttctcc ttcttaaccg
    53341 tcacaacctc ttcaaaaacc aaattggtct gctctttttc ctggttcatc atcgggtaaa
    53401 gaagaaagag actatagata accgcaacaa aaatagctag aatcacaaaa ggattgagca
    53461 taacgatgaa aaagaagaga atggttgccg ctactaaaag aagattattc ccctctttac
    53521 cagtatagta gcgaatcaaa agcaaaaaga ggaatagtat cagcagaaaa cgcgaaaaat
    53581 gctctgatac catcaaaatc agagctcctg tcagaagaca ggcttcgata aataaaaaga
    53641 ttttaaattt tctcataggt tcatcctctc ccttctattt tatcacaatt caaaaaagtc
    53701 acctcagtct gaggatggaa aaaaaggcgc tggttacgcc tttttcatct gatcctttgc
    53761 ttcttttaat tttccataaa gaagatagtc tactttttgt agatctgcta tggtggcaca
    53821 gttaagggaa cacataatca agcgtagatc tgctttccag ccttggacaa tgccaatcac
    53881 ttcttcaact gtgtaggttt caaccaattc cagaacggtt cgtgacaatc ccacagcctt
    53941 agcaccaaaa accaagcact taatcatatc cagcggattc cgaacccctc cactaaccaa
    54001 gagttcgacc ttatctttcc attcttgggc attgagaagg gcctgcatgg tagactgacc
    54061 ccattgattg aggtaatcac gctggccact acgacggttt tcgatatagg caaagctggt
    54121 gccaccacga cccgataggt ccactgtacg aacaccgaat tcataggctc tttcgattgt
    54181 cttggcatcc attccaaagc ccacttcctt gaggacaata ggaacgggaa tttgcttgct
    54241 ataatctgct agatgcgatt gccagcttct aaacttcctt tctccctcgg gcatgagtaa
    54301 ttcctgcatg acattgacat gcacttgcaa tagaacagga ttcatctctt ctacagtctg
    54361 aagtcctaac tcgacaggtt tgtccaatcc aatattggtt ccaaggagga gattgggatg
    54421 actagacttg acagaaaaag aatcatccgt tggatttttg agggctgcgc tataagaacc
    54481 cgttacaaat aaaataccac aggattccgc cacctgagcc agcttttgat tgatttctct
    54541 tcccttatta cttccaccag tcatggcatt gatataaaaa ggaaagtccc actttcgacc
    54601 agcaaactct gtcgaaagat cgatttcatc cagattgtaa agaggcaagg aagaatgaat
    54661 cagctccacc tcatcaaagc tattatagga acttttctgc tcaagggcat agaggatatg
    54721 ctcgtcctta cgatttgtcg tcatgtccta tcctttcttg atataagagc tcaatcccca
    54781 gatcggccca acgatttttt aaggttttgg ttgattgcgc atcaaaactc agggcgatgc
    54841 cacagtcacc accaccagca ccactactct tggcaacggc ctgcaaatct tgactggctt
    54901 ctttcaactg tctaagcaaa ggcgtgtaaa tatctgtact caagccttct aaaagcttgc
    54961 tggctacttc tacttgctcg ataatctttt ctgatttccc ctgttccaag gcttcgacca
    55021 aagaaaccac cgtttctttt gaggaactta aaaaattttg attgatattt tgcttgattt
    55081 gctggaccat gtgactcgat acagccactt ccttggtcca tcccactaag aaatcacatt
    55141 ctaaagttgg tttcacttgt gaaattgaaa agccccaatc acgctccaga actgtcgcca
    55201 agttttcttc ttctaaccaa gcagccacct tctggcgatc aaatgactgg tagagaacca
    55261 aatcctctgc cacaatacag gcaaggtcgc ccatggaacc attgtctcct cgcttgagca
    55321 agacagcgct agtcagcttg aacaagagct cctgatcaac agaaacatca tacagagcca
    55381 gtaaagcctt gacaaccaag acaacgacgc tgccactaga acctagacca aactttttcc
    55441 cttctcgttc cattttgcca cagatttcta gggaaaaaga tcttaaattc tgaccgcgaa
    55501 cagcgaggaa gtctcccatc aaagcaatcg tttcttgaat caagctgtag tcaggattgg
    55561 gcgttaagtc cactgcgaaa tcaaacatat ctgaatagat acggtagctg tcagaaaaag
    55621 caatctcagc cctcatatag atgggaatat cctttatcaa agctaactgc cctggctcta
    55681 aaatagcata ttcacctgcc caatagagtt ttccgcaagt tttaacagca atcatcttga
    55741 ctcaaatcct ttgtttttga cacaatcaag cgataacgct gaccgaaaat ttctgacaaa
    55801 tgctccaagt ctttctcctg acaaaagacc ttaacattgg gaccagcatc catggtaaag
    55861 tagcaggcct ctcctttctc acgaagctgg cgaacaaagt ccatagcctc ataagaggca
    55921 tccgtcagat aagaaaaggc tggactagca gtctttgtcg tagcatgcat agccagggca
    55981 tttttctccg ttaattctcc aatcttggca aaatcatttt ccttgagata aatcagcata
    56041 tcctgatagt ccttctcaga ctgacgaacc cagtcgtcaa aagtcgtcga ggtttccaca
    56101 caaagtttca tcccgtcacg gctagagatt ggttttttct tgtcctctag caccaacata
    56161 atcatagcta gtttcaagtc tgtctctaca gagtaaattt ctccactatc cttatcccag
    56221 gctcctagcg gtccataaaa actccgagaa gaagagcctg aggcaaactt ggcttcctgc
    56281 gctaactgac ttctatccaa tccaagcttg aaataagcat tacaagcctt gaccagggcg
    56341 gacaaaccac tagaacttga ggacaggccc gctgcagtag gcatattgtt ttgagtatcg
    56401 atacggacaa agccctcacc agctggacga taacggtcaa taatcttact catcttggca
    56461 tgctcgacct cattttgtag ctgaccattg atgtaaaatt cgtcagctat tacattggct
    56521 ggtaaaggcg acaaggtcgt ctctgtatac atattttcca aagttagaga aatactgcta
    56581 gtagcaggca ccatctcttt ttcttttttc tttccccaat atttgataat agcaatattt
    56641 gcgtaggaac gtactgtcac aggctctcta tccatgtctg aacagctcct ttctcttcta
    56701 atctttctgc tagttcttgt gcgtgtgtca aattggttac caaggctatg atacaacctc
    56761 ctagcccacc accgctcatc ttggcaccca gagcaccatg gctaagagtc gtttcaacca
    56821 aaaagtctgc ctcagggcta ctgactccaa tttcttttaa atgtaaatgc gcttgactga
    56881 ggatttgtcc cagtccttca gcatcttttt gtgaaatcgc aacttctgct tgctgggtta
    56941 attctcccaa ggcatgcaaa aacggtaggg catccttgcc cttattttga accacttgga
    57001 tggcttcacg agtatgacca taaacacccg tatcggcaat caccaaatag gcggataaat
    57061 ccatctcaag ttctgtaaat cctacgttct tgataaagcg aataggttgg tcactgagac
    57121 aggtcttagc atccaaacca ctaggattca tatgggcaat catctcagct cgattgacca
    57181 agatttctag tacatcatga ggcagatcag cctgatagta gtcaaatacc gcacgaatgg
    57241 ccgctatgct gatagccgct gacgaaccca tcccccgttt ctcagggata gccgagtcaa
    57301 tctcacaacg aatgcaggct tctgtgatat ccaaatactc cagtgaggca taaaccgcca
    57361 tggacaaggt atcctcctca taaaggcgcc aaggactctc tgcaggaact accttacagg
    57421 tcacctccac ctccaaaaga ggcagggaaa tggcaggata accgtaaacg accgcatgtt
    57481 cccctattaa aattatctta ctatgtgcct gaccgacacc aacttttttt gtcatttttt
    57541 ccttttacta gacgaaaaaa cgtcttattt ttcatacaag tattaattct ttcctatcta
    57601 ttttattata ttttcacaaa aaaagcgatt gtttccattc acaatcgctt ctttcattat
    57661 tgaacccatt cgccattata gttgacagaa tagccatcta cggtcgtatt cactgccaag
    57721 gcacctgagc tataagcgta gtaccatctg ccattgacct ggaaccaacc tgtcgtcata
    57781 gaacgacgaa agaaactcca taccgttaag taaagaggaa agtcgtgagg gatcatgcgc
    57841 cattgacaac ctgttttagt gacgtacaaa gtctcattaa caagtactcg tttcggccat
    57901 ttataggtgc ggtgtttgga gaaatagggt tcaatcttag cccattcttg atcgtttaaa
    57961 tcagtatcat atgctttgcg tgtcataact ctagtttaac attttttgtg aatacaagtt
    58021 ctaaataatc gaccacgaaa atttcttaag tggaaaacgc cttatgaagt atgctacggg
    58081 aaacttatgc acttaatttg acaattcaag atgtaaaaat atatactata gtagattgaa
    58141 actagaatag tacacctcta cttctaaaac atttttagaa atcgatttga ctgtcctgat
    58201 cgatttgtcc tgttattatt ttattttact ataatatttg acaagttatc ctaaaagtat
    58261 tattatgttg ttgtgttata gattgattga atctaactaa aggatcctat tcaattacta
    58321 gaactatcac atactcaagg tcagctcaca gatgagcaac tattttggtt acaatgtcta
    58381 ctaaatttaa gtcaaacaaa taatttagtc aaaattaaaa aaatagagga acataaatat
    58441 gattacaaaa cagaatgtaa tagtgttcta cgatttttac tagataaaac tgtaaattct
    58501 gaaggaagga tcacttcttc aacagaattt ggaaatttcg taagtaattt atcattccaa
    58561 cacggaatag ctggactact gtttcctcta aataaattgt accccccaga actggattct
    58621 aaaatactct ctatcatcaa gaaggcagtg acaattagaa cgacacacat atgaatatca
    58681 atactcactg ctatttggtg atgcaggcta tctatggtta ctcctacatt tattttctat
    58741 cagtaaaaat caatactatc tacaattagc aaacgtcacc gctaagaaat taatagagaa
    58801 ttatgatact ctagaagaaa tagactttgc attgggaaaa tctggtgtcc tattatcatt
    58861 aataaaatac tatcaattta ccaatgacaa tactcttaaa actttcatcc acaatagtat
    58921 atggggaaat ttatcattat ttcctacaaa gagatacagc caaagaaagc attttagact
    58981 atagctttgc tcatggatat tgtgaaattg catatgcttt atttgcctat tctaaagtct
    59041 tagaaccttc tatgttctat aatgatctcc atacattcca tgctgaatta aaaaaattat
    59101 tagaaaaagt tacttctaat actgaaaatt taggaaattt acaactttct tggtgcgaag
    59161 gaatttccgg aataatctta tatctttgta tgtacgattg tgacggaaac aaagatatta
    59221 ttagtaaata tcaagaattt gtttttaacc atcatctaaa aatgatgaca ggatattgcc
    59281 acggaataac tagcttacta caaaccactg tctacaatca aaacaaatta ctgatgaaaa
    59341 aaatccaaca ggtaatttta gcatgttctg aacgagatga tcacggttta ctgatgtttc
    59401 aaggagatag tggtaaagca gatttgtttg acttcggaat aggaagcagg gggtatattg
    59461 gtgtctatta aataataaat tcccattcga tgtgcaaaca taaggagaaa tgtatgaaat
    59521 tattttggac aaacaacata tatagacagt tgctgctaaa cagctgtttt tcatcattcg
    59581 gcgacagtat tttctacctc gccattatca attatgtggc tcagtacaat ttcgctccgc
    59641 tagcgatttt actgatttcc atttcagaga tggttcccct actatcgcaa ctctttctcg
    59701 ggattctagg agattttcaa gaaaatagag tcaaacacgc actctgtatt gccaaaatca
    59761 aaatcctgct ctacgctatt ttgacagtat ttctcgtctt gtcgcccttt tcattagttt
    59821 cagtcattat gattgtcatc atcaacctca tctctgacac cttgagctac ctgtctgcct
    59881 acatgatgaa cgccctctac atcagtgtaa ttaaggatga cctgcatgat gccatggggt
    59941 tcaggcagtc tctgatgagg gttgtccaca ttgtcgccaa tctggctggc gcattcctta
    60001 tcaatgttat aagtattcaa actatttccc ttatcaacac tctgactttt gtcattgcct
    60061 ttttgggcct gtatgttatt cgacatacct tgtatgaggt tgaaaaaagg attgaaatgt
    60121 cacatacagc actgagtttt aagaaatatt ttcaacatct taaacagtcg ctggctgtgc
    60181 tcctgaggtt aaaagatacc gtcatactac tgtttctgac gaccagtatg attgccatct
    60241 tggatgtgtc ccctcggctg attgccctcc gcttcatcca acagacacta gcacaactga
    60301 gcattgggca actcttcgcc ctgctctcca tcatcatgtc ttgtggagct atccttggca
    60361 atatgaccag cagtaatcta tttaaaaata tccgtttcac gcacctcttg gttttctgtg
    60421 agatttccct attggctcta ataactagta tcctttgtca agcctatatc gtaattttcg
    60481 tgaccagttt catcagttct acgattatcg gcattctcag ccctcgccta caagcagctg
    60541 tctttgccca tatccccagt gacaagatgg ggacggtggg ctctgctctg agcacagtag
    60601 acattctcgc cccgtccctg ctctccctat tagccctatc catagcatcg ggcgtttcgg
    60661 tgcagttagc attgatattt ttgtatctta ttttgattgc tcttatcttt tgtcaatggt
    60721 tagtcaagtt caacactcat aactaacgaa aaagcatgtg tagatttcac atgcttttaa
    60781 tctccccaat cgtcaggtca agtacaacaa agtcacttct ttgattaagc gagtgttcta
    60841 atataattat aagcgccctg tcattaccga acccattcgc cattatagtt gacagaatag
    60901 ccatctacgg tcgtattcac tgccaaagca cctgagctat aagcatagta ccagttgcca
    60961 ttgacctgga accaacctgt cttcatgtct ccattacctg catttaggta gtaccaagtt
    61021 gaaccatctt gataccaacc agttgccata gctcctgatg aacggagata gtaccatttg
    61081 ttcccaaggt tttgccaacc tgttttcata tcgccatttg gctggtctaa ataataccaa
    61141 gtggtacctt cctgatacca gccagtggcc attgctcctg aggaacggag gtagtaccat
    61201 ggagcaggtt tgcttctatc aatgtcaata gtaacatgaa aatcttgagt ccaaccctta
    61261 gcaacttcac caattggtag tggattgtaa gaatcatcac caaaatttcc tagcttattt
    61321 aaataatacc aattgccgtc ttcataaatc cagcctgtct ttacagcata attattatca
    61381 aaataataag ttctcttttc agcagataga ggatattgtt caccgtatac ttttcctgta
    61441 ttttcagacg tttttgcctc tagtacttgt ttatctgttt gttctagcaa agcaccatct
    61501 tgtccaaaat agtaccactt ctcctgaagg ccaatttcga agactggacg attatcaaat
    61561 aaatcatcac gataacctgt tccaggaatt tctaagtatt gccaaccgac aaccatctct
    61621 ccaatatcac caaaatagta agttttaccg tctattttat gccaatagat tgctttatga
    61681 tcatctttta cataatattt tctattatcc ttatcaacaa atcggccacc tgtggtattc
    61741 gcaaataccg tatttgtagc tagcaaacca aagaaaaaga ctgctagtag aacttgcatc
    61801 atttttttca aaagtttcat ttatatatcc tcctaaaacg attgtagcaa agacacgact
    61861 gcatgtcaat atataaaaac tcctcaaaaa agcagttaca caactgcaac tgcttttcta
    61921 ttcttgcatg gtgtaaccaa caccacgcac ggttttaatg tagctttttt gtcctttaac
    61981 atcaagcttg ctccgtagat agcggatata gacatctacg atatttgtct cggtcgcact
    62041 ttcatacttc caaacacttt ccaacaattg ctcacgagtc aatactttct tgcttcccat
    62101 aagtgtcgcc aaaaggtcat actcacggcg ggtcagagca atcatctctt caccacgata
    62161 aaccgtgtga tgttcaacat ctatcctaag attgcggtag gtccttggaa ctttcatcag
    62221 actgcagtgt tgatcaatga agtcccgacc tcggaagatc gccgaaatac gcgctaccag
    62281 attttcgata aagactggct tatagatgta tgaaactgca aaacgctgaa caacttccag
    62341 ctcttcttgc aagtcttccc aatgatctaa aatcatgatg actgaggcag gtttagttcg
    62401 actcaatttt tctgcaaaat cctgagccat catatctccc agattaacgt tcaataaaat
    62461 caaatcatag tctgtctgaa gagccatgga aagggctttt tgcccctcct ctaccagatc
    62521 aacccgatac tgctctttct ggagttccaa acttaaaaaa tgagctagat ttcgttcttt
    62581 ctcaagtaat aaaatccgtt tccccatggc tgacctactt atttttcgtc ataccaagag
    62641 tagtggaagg ttccttcttt gtctttacgt tggtaagtgt gagcaccaaa gtagtcacgt
    62701 tgtgcttgga tcaagttagc cggaaggtca gctgaacggt agctatcaaa gtaagtaata
    62761 gctgctgaga aagttggcac tggcacacca gcttgaaccg caagagctac gatatcacgc
    62821 actgcttgtt gatacttagc agtaacatcc aagaagtact cgtccaaaag aaggttggca
    62881 agatctgcat cgcggttgta agcatctgta atcttttgca agaaacgaga acggatgata
    62941 cagccatcac gccagataga tgcgatatct gcaaatggca agttccagtt gttttcttta
    63001 gaggctacac gcaattgagc aaatccttgt gcgtatgaaa tgatttttga gaagtaaagg
    63061 gcttgacgga ttttttcaat caattcagcc ttgtctcctt caaagttgaa ggcagctggt
    63121 tttggaagca ccttgctagc atgtacacgt tcttctttgt aagttgaaat gtagcgtgca
    63181 aacactgact cagtaatcag tgacaatggt acaccaaggt caagagatga ttggctcgtc
    63241 catttaccag ttcccttgtt acctgcagca tcaaggatgt agtctacgat tggtccatct
    63301 tggtcttcat cgtctttacg gctcaagata tcagctgtga tttcgatcaa gtagctatcc
    63361 aattcaccct tgttccactc agtaaagatt tcagccatat cctctgcaga aaggcctagc
    63421 aagtgttgca tcaagtcata gctttctgcg atcaattgca tatcaccgta ctcgataccg
    63481 ttgtgaacca ttttcacata gtgaccagct ccatcaggac cgatataagt cacacatggt
    63541 ttgccatctt ctggtgcttt agctgagatt tcttcaagaa catccgaaac caattcgtag
    63601 gcctcttttt gtccaccagg catgatagaa ggaccttcaa gggcaccttt ttcaccacca
    63661 gaaactccag taccgataaa gttgatacct gagtttgcca attcttcatt acgacggatg
    63721 gtatctttgt agaaagtgtt tcctccgtca atcaagatat cacctttgtc aaggtgtgga
    63781 agaagggctt ggatagtagc atctgtacca ggtccagctt gaaccatcag catgatacga
    63841 cgaggttttt cgattgagtt tacaaaactt tcaacgtcat agcttggtac aaaattcttt
    63901 tcaggatggc aagcaatcac atcttccgtt ttttctttac tacggttgta gatagcaact
    63961 gtgtaaccac gtgattcaat attaagggca aggttacgac ccattacggc catacctacg
    64021 acaccaaagt tagcttttgt catttgacac tcctcttgtt tcatttgttt tattttatca
    64081 tttttacttt tgaaaagaaa gaattttgta acgactgctt agtagtccaa gtcatccgca
    64141 tgaccagcgc catttccgac aaagtagcct gtcttacagt taagggtaaa gagataggtt
    64201 ccatctggct tatagaggtt gtaataacca ttgccgttaa cgatattgac acgttcaagg
    64261 atatattggt ctccagtgat atagccacgt gaacgtgaag ttgctagaat ttgttccaaa
    64321 acaccatccg caaaatccca ggcagagtta ttactatcat caatagcaga ctgattatag
    64381 gcaacacgac tggcacttct ttgaacagca acccctgcac tcgagagacc catattgact
    64441 tcactgcgac tacttctagt ctcatttgaa ctacttggtt ttggctcact agtcgtattt
    64501 gaacttgctt gacttgaact tgagctgcta gtttgacttg aacttgagct agaagtactt
    64561 gtttgctggc tcttaccaag actgatagcc ttatctagca ctttatcaag ctccgtattt
    64621 ccagttttaa tatccgtaaa tttagcatcc gatttggctt tggcattggt atccaacaca
    64681 ccatccacaa tagctggttt ttcaaattgt gcattgacat cttgaatggc cttgatttgc
    64741 gttactagac tatcatattt agatttggca agcgtatgtt cacgactacc ttccagctta
    64801 tcaagtaaag tcttgagttg actcagttta tcaaactggc tatttttcaa agccgtttta
    64861 ttgctatttg tgtaaaaggc gtcataaagt gtattaaaat catccacatc cgattgattg
    64921 gctgtagttg attgagaagt ttcaatttcc ttggtcgaac gagccacttg acgatagaca
    64981 taataagcac tgacacaaat aattactgat acaagcgcca aaacggtcaa aataaagcct
    65041 tttttacttt tcttttctga gtcctcttga tccagacgag aaaggttttg ctcctcttcc
    65101 acttcttcag tcatttctgt tggattttca tcatctagca atagaggatc caagccttgc
    65161 tcctcatcgt ccagaggcaa gggtagtaag atgtcttcag aagatggaac ttcctccgaa
    65221 gaagcttctg acttctctac agcctcacgc atctcttgaa ttaaatcatc cagactctga
    65281 gtttcaacga actcctcttt tttgtattga cgagtcgcaa acttatccgc ctcaatttca
    65341 tctctgtgtt gcttaacata cttgtccaaa atggaatcct caggcaagac tcctgcttcc
    65401 acttcttcat ttttacgaat agcttgacca actgttagct cttttgcttc atcaaaatca
    65461 aattgcggtt cttgaccttc ttttttatga cgatttcgtc tttttttact catgagtatc
    65521 cctttctatt ttacctcttg ccgtttgaca cgctgaccaa aatattgata tagatccact
    65581 ttcaaggttc cgttgtataa cttacgcttc ttatctgctt ggctaccata cttgctttca
    65641 aaagcttcat cactagtcag gataaatttg ctccaagttt tcagcggtgc aaatacttgc
    65701 cccatctcag catagagctt ggtcactcct gcatcatctg acaaacgttc accataaggc
    65761 ggattggaaa tgattactcc attgatttta tcggaacgta aatcctgcac gcgcatctgc
    65821 ttaaaagtaa tatctcctgc aacaccagct gcctgagcat tggccttagc aatttccacc
    65881 atgcgagcat caatatcaca gcccatgata tccaactcaa gcttacgttc tactttttta
    65941 gccgcttctg tgcgcacttc ttgaatcaag cgatcgctga tccagttcca ttcctcaaat
    66001 gcaaaagagc gacgaagacc tggcgccatc tttctagcaa tcataactgc ctcaatacag
    66061 aaagtccccg aaccacaggt cggatcaatc aaaggcttgt ctggatacca gttagaaagt
    66121 tgtaaaatgg ctgctgccat attttccttg ataggagcgc cacctttttc ggtacgataa
    66181 ccacgtttaa agaggctaga cccggtcgta tcaatcatga cagttgccac atctttgaga
    66241 atagagacct caatcttaaa ctctgggcca ttctccatca gaggaacccc ttctgggcga
    66301 gcatagtgtt tctgcaattt cttgacaaca gctttcttag aaatagcctg aacactgggc
    66361 tcattgtgaa gtttggactt aacacattta gcttttgaaa tcggtaaccg agctccaagt
    66421 ggtaaataat tttcccaatc taaagcgaaa actccctgaa atagctcttc aaaagtctta
    66481 gctgggaacg ttcctacgat aattttgata cgatctgctg cccgaagcca aaggttggtt
    66541 tcgataatag ctctcacgtc tccttgaaaa cgaacacgtc cattttcaac ctgacaatcg
    66601 tagcccaact ctcgcacttc acgaccaacg acagcctcaa gccctgctgc cacagttgca
    66661 attaaattaa attctttttt catgttacag tcttgcaaga cctttctata tgtccacttt
    66721 aaaaaatgag gttgagaaaa tttctcagcc ccaacctata tgcaattttc tataagccat
    66781 gttttgttcc agaagtgact aggaccactt ccttcgataa tcatctgtct accactaaca
    66841 gctctagctg atagcagtca gaatactacg ttcgtttccg catactccat gccccgacca
    66901 aaatttgggt tgctagcttg aggggtttac cgcgttccac tctctctgtt tccagaaaga
    66961 ctccgtcact gtggcacttt caagcctact ctggcctatc caaggactta gccatttcaa
    67021 ctgccgtaac gatttctcgt ccctaggctt atggtttcgc ctagcacaaa cactacaggc
    67081 atcacagcct gtgctagcat ggactttcct catgagaagc aattctcctc acgcgattat
    67141 ccaaaaattg cacatctcaa ataactactt aaaaatctga gttatctaaa atttgtttac
    67201 caaaaacttc tttttccaat ctattcaggc gtttcaaaat atcaaaattc gtcatagaac
    67261 ttgtaattgc cgcttcaagg ggttctgctt gaactggtga aggtttcggt ttacgagtta
    67321 attcttcctt caaatccgca atttcctgac gaagtgactt gaccaaggca gcataggttt
    67381 catagtcctt gatgacatcg tctaaaaact cgtcaacttc tactttatta tagccacgga
    67441 cttcacgtcc aaactcttgt tcaaaaatat ctttcgctga aaaaataata cttgccatgt
    67501 ctctctccat tctcgcttgc tagtattatt atataaaaaa aggcaaacaa aaatcaaggt
    67561 caaagcttca attttcggaa aaattttcag caagttcatt taattgatca aatgttaatc
    67621 tctttataaa atagtcctct tgatttttca tcttttggta aaaataagct agttttgttt
    67681 cattttcttc atcataaaaa agataggaac tagtcgtgtt ttccagcaaa aactgctggt
    67741 aatctcttaa ctgccccttg tgttcatagc gaggataagc atatttgaca aagtctacct
    67801 gcttaaagcg actcagtttc atctgattgc cttcattcca attttcccca tgggtttcaa
    67861 aagcaaaaat ggtggccaac tggaaaccgt attcggtttt catctcctga gcaacctcta
    67921 aaacccaata ttcaaaaccc aaactccctg taaacacaag ccaagacacc ccatctgctg
    67981 ccatagcctc taaatcttta cgtatcgctt ttttaatcaa tttaagacga ggatccttat
    68041 cagaaaataa acccaaatca aaagcagaat agcctaaaac caaagctgta gccattttta
    68101 accctttctg tgcaaattat ggtataataa agtgatgtta ttgtaccaat aaggagaatt
    68161 atgatcaact atccacataa agtttcatca caaaaaagac aaacatctct ttctcaaccc
    68221 aaaaatttcg caaatcgagg aatgtctttt gaaaagatga tcaatgctac caacgactac
    68281 tatttgtctc agggcttggc tgttatacat aagaaaccaa ctcctattca aatcgtacaa
    68341 gtggactatc cacaacgaag tcgtgccaag attgttgaag cctattttcg acaagcttca
    68401 acgacggact attctggcgt ttataatgga tattacatcg actttgaagt caaggaaaca
    68461 aaacaaaaac gtgcgattcc gatgaaaaat tttcatccac atcagattca gcatatggaa
    68521 caagtccttg cccaacaagg aatctgcttt gtccttcttc acttttcttc tcagcaagaa
    68581 acctacttat tgccggcatt cgatttgatt cgcttctatc atcaagataa gggacaaaaa
    68641 tcaatgccac ttgaatatat tcgagaatat ggatatgaaa tcaaggctgg tgccttccct
    68701 caaattcctt atctcaatgt tatcaaagaa catttattag gtggtaaaac aagatgaaca
    68761 aaccaacgat tctgcgccta atcaagtatc tgagcattag cttcttaagc ttggttatcg
    68821 cagccattgt cttaggcgga ggagtttttt tctactacgt tagcaaggct cctagcctat
    68881 ccgagagtaa actagttgca acaacttcta gtaaaatcta cgacaataaa aatcaactca
    68941 ttgctgactt gggttctgaa cgccgcgtca atgcccaagc taatgatatt cccacagatt
    69001 tggttaaagc aatcgtttct atcgaagacc atcgcttctt cgaccacagg gggattgata
    69061 ccatccgtat cctgggagct ttcttgcgca atctgcaaag caattccctc caaggtggat
    69121 caactctcac tcaacagttg attaagttga cttacttttc aacttcgact tccgaccaga
    69181 ctatttctcg taaggctcag gaagcttggt tagcgattca gttagaacaa aaagcaacca
    69241 agcaagaaat cttgacctac tatataaata aggtctacat gtctaatggg aactatggaa
    69301 tgcagacagc agctcaaaac tactatggta aagacctcaa taatttaagt ttacctcagt
    69361 tagccttgct ggctggaatg cctcaggcac caaaccaata tgacccctat tcacatccag
    69421 aagcagccca agaccgccga aacttggtct tatctgaaat gaaaaatcaa ggctacatct
    69481 ctgctgaaca gtatgagaaa gcagtcaata caccaattac tgatggacta caaagtctca
    69541 aatcagcaag taattaccct gcttacatgg ataattacct caaggaagtc atcaatcaag
    69601 ttgaagaaga aacaggctat aacctgctca caactgggat ggatgtctac acaaatgtag
    69661 accaagaagc tcaaaaacat ctgtgggata tttacaatac agacgaatac gttgcctatc
    69721 cagacgatga attgcaagtc gcttctacca ttgttgatgt ttctaacggt aaagtcattg
    69781 cccagctagg agcacgccat cagtcaagta atgtttcctt cggaattaac caagcagtag
    69841 aaacaaaccg cgactgggga tcaactatga aaccgatcac agactatgct cctgccttgg
    69901 agtacggtat ctacgattca actgctacta tcgttcacga tgagccctat aactaccctg
    69961 ggacaaatac ccctgtttat aactgggata ggggctactt tggcaacatc accttgcaat
    70021 acgccctgca acaatcgcga aacgtcccag ccgtggaaac tctaaacaag gtcggactca
    70081 accgcgccaa gactttccta aatggtctcg gaatcgacta cccaagtatt cactactcaa
    70141 atgccatttc aagtaacaca accgaatcag acaaaaaata tggagcaagt agtgaaaaga
    70201 tggctgctgc ttacgctgcc tttgcaaatg gtggaactta ctataaacca atgtatatcc
    70261 ataaagtcgt ctttagtgat gggagtgaaa aagagttctc taatgtcgga actcgtgcca
    70321 tgaaggaaac gacagcctat atgatgaccg acatgatgaa aacagtcttg acttatggaa
    70381 ctggacgaaa tgcctatctt gcttggctcc ctcaggctgg taaaacagga acctctaact
    70441 atacagacga ggaaattgaa aaccacatca agacctctca atttgtagca cctgatgaac
    70501 tatttgctgg ctatacgcgt aaatattcaa tggctgtatg gacaggctat tctaaccgtc
    70561 tgacaccact tgtaggcaat ggccttacgg tcgctgccaa agtttaccgc tctatgatga
    70621 cctacctgtc tgaaggaagc aatccagagg attggaatat accagagggg ctctacagaa
    70681 atggagaatt cgtatttaaa aatggtgctc gttctacgtg gagctcacct gctccacaac
    70741 aacccccatc aactgaaagt tcaagctcat catcagatag ttcaacttca cagtctagct
    70801 caaccactcc aagcacaaat aatagtacga ctaccaatcc taacaataat acgcaacaat
    70861 caaatacaac ccctgatcaa caaaatcaga atcctcaacc agcacaacca taacatttat
    70921 cacccagatt tttctgggtg attttgtcat agcactattg tatttatgtg cttaacaaaa
    70981 gcctgagaag atgtcttctc aggctttttc tgtactataa acctcattgg aaaagataga
    71041 gactgcttcc gtaatcttgt taagaggttt tactaaatac tagtctttct tcgtttttac
    71101 tacaaagaga gcagataggg ctagactaac acttgctagg aagagggctg tgtcagattg
    71161 actctcacct gttgctggca agatttgttc aggtgtttct ggtctagcta tttcttgctt
    71221 ataatctggc gtcttacctt gatcggaaac taaagagcta agtttaaact caggtttctc
    71281 tacagttgga gcatctggtt tcgtagcaga atcttttaat tggttgagat aatctgcaaa
    71341 gtattccacc attctttccg tcaagagatg gttatccgtc gcatatttca tgcttgcctg
    71401 aacgctagct acttcctctt gattgtcttt gtctgttaat ttctgagctt tagccaaagc
    71461 tgcttcatag cctgacaagt caagaggtgt ttctgctacc tgtggacgag taaagatgag
    71521 ttccgctgca gattggtatt tatcgccacc atctccgtaa gtcttagtac ctgtaaggac
    71581 aattttctta gccttaattg tcttaccaaa atcaatgtct tttggcttat tgttatctgg
    71641 ccaatcagtt gcagtaaagg tatgctcctt gccagactca tctgtcacaa caagtttcac
    71701 atcacgcaag ttaccatttg aacctgatcc acgtggaacg taacgaagtc cagtgatttc
    71761 agttggttct ttcaagacca tggttgcagg cttgcctaca tctccaccat tccaagatgt
    71821 atgccataaa ctagataagt ttccatcaaa ggcatttgca agaccttctt gagcctgagc
    71881 aggagctgta agacttgcaa agtcatctgc taccaaagcc gttttcttct gaaccaaagc
    71941 attcttcaag gcttcaatct tggcaatctc tgcacgcgct tcttccacac tgatatcatc
    72001 atcggcctga ctaaggttaa agaccgcctc tttcaaagca tccatagact ctttggtgta
    72061 gttagtcatg gcaaccgttg gcaagtagtt cttcagagca ttttctgtca acatcttacc
    72121 tgttagggta atttcttcga tttgaagatt atccatcatg aagtcgttat aaccacggaa
    72181 gttggcattt ccaccagaat caccacgagt attacttgca ttgccagttg agtagatacc
    72241 tacccaagta tcccctgttt ctgcacctgt cacaaggaag gttgccttct tggctttctt
    72301 agaatctgtc caagtatttg gcaattcatg catttccaag ttgcttgctt gagtgccacg
    72361 acgacctgac tggaattctc ccttaccgac tacaaaagca taggtattgt ctgaacctgc
    72421 ttcgtattca aaggttacac ggtaggtctt acctgcttca aaacggaagt tttgtgggat
    72481 ggtttggtaa accaagttac gacggctcac tagtccattt gtcttgagtg accaatttcc
    72541 ttcgataaca tcatcgactt tcttaccgtt ccaaccacgt tgtgtatatg gatcgtgttt
    72601 ttcagacaag tgagtgcggt tgtcttcgac accttcgaca ccacccacta caaatgggaa
    72661 gattccttga gctacatttt caaagtcttg cttgaaggtt ccttgacctg tatcgtgctt
    72721 gtctccatac atgcttgaat tgttttcaaa ggtacgaatt tcatcaaagt aagttgcttg
    72781 atcaccagct tcacgactca atgtcagagt aacatttgag acgtccgatc ctgttgtaaa
    72841 gaaggcgtac atgttttgga agtaacttgt atcgttaact gtagcattgt tacgacgtgt
    72901 attgtgggcg taggctttta catagttgag ggcgagagac ttattggtat aagtagtcac
    72961 ttctttttca ccagtattca cagtgatact tgccttggca ttactacggt tatcgacacc
    73021 gacataaacg gcatacttgg tatttggttt caagccagtt aatttctgag tgagactaac
    73081 tttttctttg tttccttgaa tacgaagcat atcgtttgcc ccttgagact tgacaatttc
    73141 tgccttagaa gcatcgcctg aaatggtcca atgtttcaag gtaccactgt taaatccttg
    73201 gtcatagatg tgcatgcctt cactccatga catttcagga ttggtttgtt ttgaacgata
    73261 gagaacgtat ggttgatttg ctagaagatc tagggtaatt ttaccatctt ttacagttag
    73321 ttcttgctct tctgtcttac cttggtcagt tagcttgtaa aggtaaacct tgctctttgc
    73381 ccaatcgctt ggaagggtcc aagttgttgc accggcctgc gtattgaagt agtacatctt
    73441 ttccttatca gtagaaagtt tcttaccatt tgcatcccag ttccaaggag tcaagtaagc
    73501 tgaaccatct tggatgacac gtccgttgag agttactgta cgttcgcgat attgtggact
    73561 attgacatta tttgacttac gagttacaac tactttatta ttgtcagcat ctaccaattc
    73621 cactcgcatt tctggagtcc atttataggt actaccgtta tcggtcatag tcaccggtgt
    73681 accattttcc catttactta cagtgaagtg ttggaagtac ttagtcatga cgtcatgggc
    73741 aaataagttg gttacatagc cattgtagtc acttcttccc tgccagcctt caaagtcttt
    73801 catgctgtag ccacctagca gtggatagtt ggctgcacca ccataacttc tgtagtcccc
    73861 aacccaagca tctttttggt ggttacggat aaagcgggtg atggcactgt tgataccttt
    73921 attggtgtag ccaccgtagg tcaagtcagc tgcccagtga tggaaggtag agtcgtactc
    73981 accaccatgg ccccactcga tcgcaaagcg ccagccttgt ttgttaattt ctttagcaag
    74041 aacgtgggta gcccaggcac cgttatcacc tgattgacca ttaccccaaa cgtccacata
    74101 gataaagtcg agaccgtcac caagtttttt cttcaaatct tcccaacgtg ccaaacgacc
    74161 atgagctagg tcataggcag catcaatgtt gataccttga tctagccagt tccaaccata
    74221 gctatagctt ccatctggat tcttacggag aattttttca ttgaagtatt tagactcagg
    74281 ataagtttct gaagcgttaa cgtggatacc tagatgagct ccatatttct tagccttctc
    74341 aattagggtc ttgaagtctt cgacaccacc gatacgctta ccaatatcag catagttcaa
    74401 gtgaccagag tcatggcctt cgctaccata tcctttaagg aaaacacctt gcccaagacc
    74461 atctgtgtgg agattgattt tcttgatacc atccaaggtc ataaggaatg gattttgtgc
    74521 ttgagaacca aagttcatcg cgatacggta agctgtgata tccttaactt tttcccaacc
    74581 ttgaggattg ttcataatgc tacgataagc aatggcacca tcttgccaat cgactttctt
    74641 gtctgcattg gcatcttcag tgataacaac cttagcactt ggaagttcct tcgtgtattc
    74701 tgggaaaaca atgcccttat aagctttttc ccattgccat tcagagctgt ggattcctac
    74761 atagttggca tttccgactg tttctttata agctgtcaaa cgagtccagt cattcgaacc
    74821 accaccatag ctattttgag agttactcca aacaccagca gcaagcttat ctgtagaaac
    74881 aaatccatac atgtaaccct tggctaggtc tttcattgga ttggttacat cgatatgatc
    74941 atctccgctg acatgcgtat tgtttgacat ggttgcccca tcaaacttag caccagtttg
    75001 atcactagaa acagagacta aagcattgcc gaggaaacta atagaagaaa gtagttttct
    75061 ttcgtcatca atcttttgac ctggagtgac ttgattgtgg ttgacaatct tggtcacatc
    75121 aaagtgcaat tgattgtcca caacttgcaa gcgtactgtc atttccgcat tgattaagtg
    75181 agcatcatcg cgaagcttca tcaagtactc tgctgttgtc tcattgattt tcttataagt
    75241 gacttcaggg gtgattcggt ggttattgat aaagacttgg ttgaactgtt gcacctgtcc
    75301 tggcaaagta tgtccattca agctgtattc cttgacacga gggaaggctt ggtcaatcac
    75361 tgctttgagg accttagact ggatcgtatc ataagtcacc ttgctatcgt caacaaccgg
    75421 acctgtttct ttctgggcag gagtatcatc cgcttttacg ccttcttgat tgtctgtttt
    75481 aacgctgaca actgtacggt cattgccata agttcctgcc ttgagaagga tcttcttctc
    75541 atttttaaga ttatcattga ccgccccagg cagtgtcact gtgtcaaaga gattgacatc
    75601 gttattgctg gcattgagtt gtccatctga cttgagagtg atagaaagac ggtttacaga
    75661 acccggttct ggtgcaacta cacggttgcc tttataccat gtgctattac ctggagtttt
    75721 gtattcccag aaccagccat ccttgtcata accgacaaaa acattattat tggtatcttt
    75781 aaatttcagg aagacaccaa agcgtgattt gcccttttca gaatcttctt tgaaggttaa
    75841 atcaacagtt gcatttccat tggcatcaac ggtcaagccc ttcttttcaa acagggctgg
    75901 tttgcctgcg ttatcatttt gagcagttga gaatagttgg ttgtagcgga cacctttttc
    75961 ttctcggata gtgactgttc cctgttgttc ttttttctct accgtttgcc attcaggagt
    76021 taccgtctta ggtgtttcag gtttagcagc tgcaggttta tcctcttttg gtttttcttc
    76081 agccggtttt tctttttcaa gtgctaatag ttcttcttct gtcttaggtc catctgtaac
    76141 ttctggagaa ccttggtctt ctcccacctt aggcgcttca aaatcacgcc catcattctc
    76201 gtttgctgtt gcaagagcag tagctaaatc agctggtaag ttcgccgtgg aaccagactg
    76261 cacgctatct gcaagaaccg gacttgtccc aaagaatgca gctccaatca taacagaagc
    76321 aacacctaat gaaaatttcc gaatactata tttacaacgt ttttcaaata atcctttatt
    76381 cataaacttc taaatccttt cattttttag caagcgttta catttccttt ttaaaaaata
    76441 ctccttcctc tgaaagtgca atgcttaacc ctgataaata aaaaataatt gtacttttaa
    76501 tataacaaat aatagctgag aaagcaatag gaaacaagta aaattaacaa aaattttctc
    76561 tattctgaca aaaagaggct ccaacttttg ggggtcagta catttagaat ctttctttac
    76621 aaatgtaaaa aaggattcag cattcaagag aaatactaaa tcctttctta tattttgcaa
    76681 cagttatttc acatgttttg cgagatcttc ttgagccttt ttattagact cttctttttc
    76741 tttcatccat ttttcctgag ctttttggta ttcatctaca gtgactgcct tgtcttgaag
    76801 ttccaagtat ttatacaaga ctggttcact tgtaccttta tttcctgaca atgcaaatgg
    76861 tattgtaaat ggtaccatct tagacaagat tgggcgccct gtacgagatg tagttggaat
    76921 aatcaaagca ctatctgtca accaagcttg ggctgcagcg tatttatcat agcgtttagc
    76981 aacatctgta gcctcatcac cagcctcagt gaccaatttt tcgtagtcat atagacctac
    77041 ttttttagca gctacattat cttcccctga gtcaaaccct aaatatgttt tagtactttc
    77101 tcctacagaa ggtttgataa tatcaaggta ggttgatgga tcggcaaagt ctggacccca
    77161 accgacatta tctgataaat cccagtcttc gccagcagca ttttcagcaa aatatgtaat
    77221 attgtttact tcgtcttttt gtagttgttg gatatcaata atgacattat cagctcctaa
    77281 agttgcttcc aaggattgtt tcatagattg gacgcgctga acttttgtag ttgctgtctg
    77341 gtcaactggc atatccaaat gaattgggaa agtcacacct tctgcttgta aggctgattt
    77401 agctttagca aattcagcct tggctttttc tggattgtaa agaccatcct gagaatctgc
    77461 aagattaaca tccttccatt catccccata agtgaccaat ttctctttga ccatatcgcc
    77521 aaagttttta ccatctgctt gaacaaatgt tggtggaaca aagatattac gtaagatttt
    77581 gcttgctcca gtttgtccat tcaactgaga ggcataggct gtacgatcaa aaccaaaggc
    77641 aatagcctga cggaaatcct tgtttaagag agccttttta gtcgatgcct tttgttcgtc
    77701 gctggtctta gatgtatatt tataggactg acggtcaata tttgtaccaa ctagatacgt
    77761 aatagagcct tgttgagtat agacaatatt gtccttcata ctcttctcaa gctctgcgaa
    77821 acttgcactt gttggataga gacgagctgc tgtaaggcta ccatctttaa agttttctgc
    77881 aggtttgctg gtatcttgac catcccagaa tgacaattta actttgtcaa catgcacatt
    77941 gtccttatcc cagtagttcg gatttttcgc aaattcaaca gaggattttg tcacaatgga
    78001 tttcaacaaa taaggaccgt tatacaagag actacttgga tccgtcgctt tggcaaaatc
    78061 atcccctttt gagttcaaaa actcttcatt aactggcgca agcacaccca tggttgtctt
    78121 agaattccag aagctttctg gtttgttcaa agtgtactga actgtctgat catccaaagc
    78181 cttaattcct acttgtgaga aatctttgat ttcccctttt acataggcat ccaacccttt
    78241 gattgattct tgaacaaggt aaagagcatc tgatttttta tcagcagcat attttagtcc
    78301 tgttacaaag tcttgagctt tgactgccgc gtattcttca ccttcagaag tataccattt
    78361 tgcatcctta cggatagtat aagtgtaagt caatccatcc ttggatacag accaatcctc
    78421 agccatagac ggcacaaagt tcccgtagcg atcattttct agcaaaccat caaccacgtt
    78481 actggtaata tttgctgtcg cagccttagc agttgtcaaa tagttgaggt tatcagggtc
    78541 tgtctcataa atgtatgaga atgtcttctc acctttagtg cttgaacctg atccagagca
    78601 tgcagctaaa gtagtcgccg ccaataatgt cacgcccgca agggcaagta gttttgaact
    78661 tttcatcctt ttctccttta aaactttctc tccattatag actcttttca gaaagttgtc
    78721 aacagaattt tcagaatttt tgaaaattat ttttcaaata acatctttgc aaaaaatatg
    78781 aatatcgtaa ccgcccaata acgaagtcta ttgaaaaatc tccagactag agaactcacg
    78841 gatagttcct aatctggaga tttcttattt gcacttttct tgtacaactt tagtccacgg
    78901 taaataggcc tctaaaatct ctttgtttac gagagtttcc tcgtttggaa gacattctag
    78961 aagataggat agatatttct cgctatttaa ttataatagc tcttgcttta gctccttcaa
    79021 aactttgaga aaataaccac cctcgctttt ttaaactgag cttaggctaa aagagtccac
    79081 tggactcttt
//
LOCUS       DAVBIC010000003        68908 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.003, whole genome shotgun sequence.
ACCESSION   DAVBIC010000003 DAVBIC010000000
VERSION     DAVBIC010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 68908)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 68908)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..68908
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.003"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            1..314
                     /locus_tag="VQ664_000160"
                     /pseudo
     CDS             1..314
                     /locus_tag="VQ664_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            311..529
                     /locus_tag="VQ664_000161"
     CDS             311..529
                     /locus_tag="VQ664_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2788408.1"
                     /translation="MSISPRFEALEQAIASKDLEKVREAFKKMNSTWTINESVVRDNS
                     TAHYGRVETAISFLPSSMETEPTDESGT"
     gene            complement(586..870)
                     /locus_tag="VQ664_000162"
     CDS             complement(586..870)
                     /locus_tag="VQ664_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HET2788409.1"
                     /translation="MARKETMAERKYCKMKKDIHPEYRPVVFMDTTTGYQFLSGSTKR
                     SNETVEFEGETYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(924..1859)
                     /locus_tag="VQ664_000163"
     CDS             complement(924..1859)
                     /locus_tag="VQ664_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HET2788410.1"
                     /translation="MEICQQILEKIKEYNTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQKILKQYNVTDAETAAIVGAPGRIDSVSLWGIFVEQADGHYRVRLRSKIHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            1963..2406
                     /locus_tag="VQ664_000164"
     CDS             1963..2406
                     /locus_tag="VQ664_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HET2788411.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSTGAEKGSECVKVDLSAEEEDIERLEQFAEELAAKVG"
     gene            2522..2788
                     /locus_tag="VQ664_000165"
     CDS             2522..2788
                     /locus_tag="VQ664_000165"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HET2788412.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREEVIFEKVRSRVEDKRYQETIVATFSYILKRSRDYQDQNIK"
     gene            2785..3159
                     /gene="crcB"
                     /locus_tag="VQ664_000166"
     CDS             2785..3159
                     /gene="crcB"
                     /locus_tag="VQ664_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HET2788413.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIFLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYFSLV
                     LYLLLSIGGGLLLAYYLGRKKW"
     gene            3153..3482
                     /gene="crcB"
                     /locus_tag="VQ664_000167"
     CDS             3153..3482
                     /gene="crcB"
                     /locus_tag="VQ664_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HET2788414.1"
                     /translation="MVIVYLAIACGLGALVRYFFSRYNQASKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            3601..3948
                     /gene="rplS"
                     /locus_tag="VQ664_000168"
     CDS             3601..3948
                     /gene="rplS"
                     /locus_tag="VQ664_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HET2788415.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            3991..4062
                     /locus_tag="VQ664_000169"
     tRNA            3991..4062
                     /locus_tag="VQ664_000169"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4024..4026,aa:Arg,seq:cct)
     gene            complement(4229..5227)
                     /locus_tag="VQ664_000170"
     CDS             complement(4229..5227)
                     /locus_tag="VQ664_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001008999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAP domain-containing protein"
                     /protein_id="HET2788416.1"
                     /translation="MNFFSKLFNLKQNNHNRDTNSDCNNFYLNELECGLTPGQLILID
                     WTQKTGRNYNFPRYFKYSLQIDPESTHNQLYKLGYFTKNKTLSYLTVVELKTILSKHN
                     LATSGKKAELITRIINNVNIDNLDIPFEFKLTKEAQNLIIEHSDYIKAYYDKDISMED
                     YCKEKNNISFKATFGDIKWSLLNKQAHRNTVSGDFGCLSNTRKAQGRHLEQEGNIKHA
                     LIYYIESLIITISGLENNFSATDYPVYYPDSIPDYSLKHIQTLMESLSDDDYDFAFDE
                     ALFRFSILNANHFLSKEDIDYLRVNLPRSTAEEINNYLKKYECYSPLNNLELDDFE"
     gene            complement(5270..6076)
                     /gene="yidA"
                     /locus_tag="VQ664_000171"
     CDS             complement(5270..6076)
                     /gene="yidA"
                     /locus_tag="VQ664_000171"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HET2788417.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDQGDYVVTFNGALVQETATGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGKYTVHESTLVSMPIFYRTPEEMAGKEIVKCMFIDEPE
                     ILDAAIEKIPAEFYERYSINKSAPFYLELLKKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRPMLEVVGNPVVMENGNPEIKKIAKYITKTNDESGVAHAIRTWVL"
     gene            complement(6089..7393)
                     /locus_tag="VQ664_000172"
     CDS             complement(6089..7393)
                     /locus_tag="VQ664_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HET2788418.1"
                     /translation="MNEKVFRDPVHNYIHVNNQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTVTAALLHDLGHGAYS
                     HTFENLFDTDHEAITQEIIQNPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPVENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPEDKNFFARTSPHLLPFFEKNVTLTD
                     YLALDDGVMNTYFQLWMTSPDKILADLSQRFVNRKVFKSITFSQEDQDQLTSMRKLVE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESQNPRTQIEILQKNGELAELSSLSPIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLHLIENDHFTPNKN"
     gene            7465..7842
                     /locus_tag="VQ664_000173"
     CDS             7465..7842
                     /locus_tag="VQ664_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HET2788419.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKGDYSYLLFYNEEKEK
                     VVIKFHGQELMMSRFSNPKTIMRFLKDSDSLAYIPTPMGMQEFIIQTSHYQVDRQKIE
                     LDYQLQNQEGHPFASYQLEITWG"
     gene            7933..8265
                     /locus_tag="VQ664_000174"
     CDS             7933..8265
                     /locus_tag="VQ664_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009660419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HET2788420.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDDFLQEQIEI
                     LTSIDNRE"
     gene            8277..9848
                     /gene="ffh"
                     /locus_tag="VQ664_000175"
     CDS             8277..9848
                     /gene="ffh"
                     /locus_tag="VQ664_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HET2788421.1"
                     /translation="MAFESLTERLQNVFKNLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKALAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPD
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(10043..11326)
                     /locus_tag="VQ664_000176"
     CDS             complement(10043..11326)
                     /locus_tag="VQ664_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HET2788422.1"
                     /translation="MKQESTVDLLLDVDQRPSAGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMIATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLKANWFE
                     IPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLLGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
     gene            complement(11629..12342)
                     /gene="rsmG"
                     /locus_tag="VQ664_000177"
     CDS             complement(11629..12342)
                     /gene="rsmG"
                     /locus_tag="VQ664_000177"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HET2788423.1"
                     /translation="MKPKTFYNLLAEQNLPLSDQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            12436..12996
                     /locus_tag="VQ664_000178"
     CDS             12436..12996
                     /locus_tag="VQ664_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HET2788424.1"
                     /translation="MTWIILGVIALIVIFVIVSYNGLVKNCMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTSEEEKSVPKVDFSGLGD"
     gene            12998..13897
                     /gene="htpX"
                     /locus_tag="VQ664_000179"
     CDS             12998..13897
                     /gene="htpX"
                     /locus_tag="VQ664_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HET2788425.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALASAITMLSSMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGFQKLFYTHPPISERIERLKQM"
     gene            complement(13941..15500)
                     /locus_tag="VQ664_000180"
     CDS             complement(13941..15500)
                     /locus_tag="VQ664_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET2788426.1"
                     /translation="MHYRHSRKGNSMIKINHLTITQNKDLRDLVSDLSMTIQDGEKVA
                     IIGEEGNGKSTLLKTLMGEDLSDFTIKGDIQSDYQSLAYIPQKVPEDLKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQEIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYDSYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQNVETALRATKDSTAGR
                     LLAKKMKTVLSQEKRYEKTAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLAQELQLTVRGQEKIGIIGPNGVGKSTLLAKLQQLLNDKREISLGFMPQDYHK
                     KLQLDLSSIAYISKTGEKEELQKIQSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEVCSIIYRMTE
                     HGLKLVNLEDL"
     gene            complement(15739..16056)
                     /locus_tag="VQ664_000181"
     CDS             complement(15739..16056)
                     /locus_tag="VQ664_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HET2788427.1"
                     /translation="MEDKKLIQLLSKLNKSYQNCKQGTADDIRLQELLNTTMQELKKT
                     EKLNNSILIDLEKFYQPTSPLIGLGSLKLNDQARTAWRNYDKIHYEHVKHVLSLYGPV
                     FGF"
     gene            16235..16777
                     /locus_tag="VQ664_000182"
     CDS             16235..16777
                     /locus_tag="VQ664_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HET2788428.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNQLDQEVLDDD
                     LVLPIENGELDLAESVSDNILLNIPIKVLTAEEEAGQGFISGNDWQIMTEEEYQAQQA
                     VKKEENSPFAGLQGLFDGDE"
     gene            16777..17406
                     /gene="nth"
                     /locus_tag="VQ664_000183"
     CDS             16777..17406
                     /gene="nth"
                     /locus_tag="VQ664_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HET2788429.1"
                     /translation="MVLSKKRARKVLEEIIALFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            17617..18138
                     /gene="pyrR"
                     /locus_tag="VQ664_000184"
     CDS             17617..18138
                     /gene="pyrR"
                     /locus_tag="VQ664_000184"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HET2788430.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            18157..19080
                     /locus_tag="VQ664_000185"
     CDS             18157..19080
                     /locus_tag="VQ664_000185"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HET2788431.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGAELFFAGPEEWRSQEFADYGKFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            19130..20209
                     /gene="carA"
                     /locus_tag="VQ664_000186"
     CDS             19130..20209
                     /gene="carA"
                     /locus_tag="VQ664_000186"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HET2788432.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            20521..23697
                     /gene="carB"
                     /locus_tag="VQ664_000187"
     CDS             20521..23697
                     /gene="carB"
                     /locus_tag="VQ664_000187"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HET2788433.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKERPDALLPTLGGQTGLNMAMEL
                     SKNGILDELGVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEIPELAAVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDQVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIRSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKNVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
     gene            complement(23972..24781)
                     /locus_tag="VQ664_000188"
     CDS             complement(23972..24781)
                     /locus_tag="VQ664_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HET2788434.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKHDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDQFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNIPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKN"
     gene            complement(24783..25586)
                     /locus_tag="VQ664_000189"
     CDS             complement(24783..25586)
                     /locus_tag="VQ664_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HET2788435.1"
                     /translation="MKQLTVEDAKQIELEILNYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYKLLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPMDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRLVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSATFDKT
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            complement(25596..27083)
                     /gene="tacF"
                     /locus_tag="VQ664_000190"
     CDS             complement(25596..27083)
                     /gene="tacF"
                     /locus_tag="VQ664_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HET2788436.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFTDNPIVKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGDILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNHIVAPEYYLLTTML
                     SEASLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFVYPVDMVINLP
                     FLINTGLIVLLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            27419..28126
                     /locus_tag="VQ664_000191"
     CDS             27419..28126
                     /locus_tag="VQ664_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HET2788437.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVSHAEDLVDKYLPLYKERIIITKGGADRNTSIKKIIEAIDAYRPL
                     TPEDIVVTHDSVRPFITLRMIQDSIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            28131..29153
                     /locus_tag="VQ664_000192"
     CDS             28131..29153
                     /locus_tag="VQ664_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HET2788438.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPEAEIVVIGRHWEKLELFSFAKECYITDNI
                     PEELAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLI
                     LVGSSRSGRIDFKNAIQMMEVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            29170..30039
                     /gene="licA"
                     /locus_tag="VQ664_000193"
     CDS             29170..30039
                     /gene="licA"
                     /locus_tag="VQ664_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HET2788439.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAITLDSTSI
                     KTKFDKIAPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGEDFGDYGVNRYQRA
                     VKGLASYGGSDEK"
     gene            30029..30907
                     /locus_tag="VQ664_000194"
     CDS             30029..30907
                     /locus_tag="VQ664_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HET2788440.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAAAHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFTAVANGQL
                     LGLMIVFAAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAVVFLGAPLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            30919..31608
                     /locus_tag="VQ664_000195"
     CDS             30919..31608
                     /locus_tag="VQ664_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HET2788441.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQNIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYASGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     HKLEEILKNEN"
     gene            31706..32554
                     /gene="dprA"
                     /locus_tag="VQ664_000196"
     CDS             31706..32554
                     /gene="dprA"
                     /locus_tag="VQ664_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HET2788442.1"
                     /translation="MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDV
                     LAEFEF"
     gene            33438..34481
                     /locus_tag="VQ664_000197"
     CDS             33438..34481
                     /locus_tag="VQ664_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HET2788443.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGHNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEYFFQYIKDKEAKEK
                     EKANKFYTESEEQ"
     gene            34648..36735
                     /gene="topA"
                     /locus_tag="VQ664_000198"
     CDS             34648..36735
                     /gene="topA"
                     /locus_tag="VQ664_000198"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HET2788444.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNDEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQNGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMVVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            36956..37315
                     /locus_tag="VQ664_000199"
     CDS             36956..37315
                     /locus_tag="VQ664_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HET2788445.1"
                     /translation="MRIIYLIIGFLSLTLAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQAYVADFRETKSIARERKKKIIVSIYVLMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            37408..38040
                     /locus_tag="VQ664_000200"
     CDS             37408..38040
                     /locus_tag="VQ664_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HET2788446.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDIRLTAQAGSQGVVFGALTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQPEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLENRQTFIDQVGVTQLHGTKVVF"
     gene            38084..38740
                     /locus_tag="VQ664_000201"
     CDS             38084..38740
                     /locus_tag="VQ664_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HET2788447.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVYMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            38759..39853
                     /locus_tag="VQ664_000202"
     CDS             38759..39853
                     /locus_tag="VQ664_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001010962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HET2788448.1"
                     /translation="MNFQLAKYSLLKRFLENIGFTTLEEYGAIFKYLIENVKTDRQII
                     YSPHCHDDLGMAVANSLAAVKNGAGRVEGTINGIRERAENAALEEIAVALNIRQDYYQ
                     VETSIVLNETINTSEMVSRFSGIPVPKNKAVVGGNTFSHESGIHQDGVLKNPLTYEII
                     TPELVGVKILLGKLSGRHAFVEKLRELALDFTEEDIKPLFAKFKALVDKKQEITDADI
                     RALVAGTMVENPEGFHFDDLQLQTHADNDIEALVSLANMDGEKVEFNATGQGSVEAIF
                     NAIDKFFNQSVRLVSYTIDAVTDGIDTQDRVLVTVENRDTETIFNAAGLDFDVLKASA
                     IVYINANTFVQKENAGEMGRSVSYHDMPSV"
     gene            39865..40902
                     /gene="leuB"
                     /locus_tag="VQ664_000203"
                     /pseudo
     CDS             39865..40902
                     /gene="leuB"
                     /locus_tag="VQ664_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
     gene            40899..41168
                     /locus_tag="VQ664_000204"
     CDS             40899..41168
                     /locus_tag="VQ664_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HET2788449.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKSKARRRVWRIPEKILLIL
                     AFTFGGFGAWLAGIIFHHKTRKWYFKIVWFLGMVTTLVALYFIWR"
     gene            41172..41531
                     /gene="leuD"
                     /locus_tag="VQ664_000205"
     CDS             41172..41531
                     /gene="leuD"
                     /locus_tag="VQ664_000205"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HET2788450.1"
                     /translation="MAGSSREYAAWALADYGFKVVIAGSFGDIHYNNELNNGMLPIVQ
                     PREVREKLAQLKPTDQVTVDLEQQKIISPVEEFTFEIDSEWKHKLLNSLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            41693..42261
                     /locus_tag="VQ664_000206"
                     /pseudo
     CDS             41693..42261
                     /locus_tag="VQ664_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019771122.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="translation factor (SUA5)"
     gene            42355..42420
                     /locus_tag="VQ664_000207"
                     /pseudo
     CDS             42355..42420
                     /locus_tag="VQ664_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849983.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="translation factor (SUA5)"
     gene            42583..44514
                     /locus_tag="VQ664_000208"
     CDS             42583..44514
                     /locus_tag="VQ664_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HET2788451.1"
                     /translation="MNKRKVSLEDFYKWYSLNKEELLNKATVGEKFNDKLKEEFLQEW
                     PLDRILTMSIDEYVIGKGQQNKSLCYALEKGKYKNLFLGISGGSASKFGIYWNKKTNK
                     YKDQANNEISELDQRFSKLKSDLYEIIKEGIRFNFENPIFDMKRSTNEFIGRSAMVTK
                     LLCIYTEGDPFFGVNINSQKEFWNHFVSQTNQGGPYLQNHKIIELMSKTYPELEPSKL
                     GTMLFEYSKLFMENKEDNSTMDSSNNFRHQLTQSLLKSPNLILRGAPGTGKTYLAKEI
                     AKELTDGNEDQIGFVQFHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFKDFCQKAKE
                     TQLIGGQDNFDEAWDSYLEYINVAEEKEYITKTSYLSVNSRQNLSVNYDSGVPGWSLP
                     SKYVYELYKDKNYNKQEYYKSGGKTVLETLRKRFGLKDYVSPTEIDTDKKFVFIIDEI
                     NRGEISKIFGELFFSIDPGYRGEKGSVSTQYANLHETDEKFYIPENVYIIGTMNDIDR
                     SVDTFDFAMRRRFRFVEVTAEGQVGMLDKELNIHAEEAKIRLRNLNAAIENVQELNSH
                     YHIGPSYFLKLKDVDFDYELLWSDYIKPLLEDYLRGSYDEVETLETLKKAFELTNNEQ
                     KDQAVADDNESDENDDADY"
     gene            44501..45853
                     /locus_tag="VQ664_000209"
     CDS             44501..45853
                     /locus_tag="VQ664_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HET2788452.1"
                     /translation="MRITDNQHKIIKEKFVEEYPKLSNLLLDRTLESLSQDERIFIFP
                     NDLTHTPDLDKKQKILETINQEIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKVLHINLTSLDVALSREERLYQLLMYLFPKYLQAAIRKGLYKEYHRFSHNDSHVKGV
                     IDVRNHLKKNLPFTGNIAYTTREFTYDNPLMQLVRHTIEYIKNQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKIIRGNQSKPIRHAYFHEYRNLQELCLMILNQEKHGLG
                     YQDQKIYGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFSVGKRKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKAEKAGLVFPSKDKVIDNEMGNL
                     AGYGALLKKWSIQIPQKSSSYSAFCKMMENSDYSAFCKMMENSEENFKAIIDEEVGRK
                     "
     gene            46028..47014
                     /locus_tag="VQ664_000210"
     CDS             46028..47014
                     /locus_tag="VQ664_000210"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HET2788453.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKQMHDQGLIASISVGVKDYEY
                     DFVSQLKTDAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            47078..47149
                     /locus_tag="VQ664_000211"
     tRNA            47078..47149
                     /locus_tag="VQ664_000211"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:47111..47113,aa:Arg,seq:ccg)
     gene            47332..48030
                     /locus_tag="VQ664_000212"
     CDS             47332..48030
                     /locus_tag="VQ664_000212"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HET2788454.1"
                     /translation="MKELQTVLKNHFAIEFADKNLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFDQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVMIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            48021..51560
                     /gene="smc"
                     /locus_tag="VQ664_000213"
     CDS             48021..51560
                     /gene="smc"
                     /locus_tag="VQ664_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HET2788455.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKSEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELAQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLAALEDKRNS
                     LSKEKSDKESSLALLEGNLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSRQLSQKQADQLEKLKEQLAIAKEKASQQKEELETAKEQVQK
                     LLADYQAIAKEQEEQKTSYQAQQSQLFDRLDNLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDMHYQTALEIALGASSQHIIVEDEESATKAIDFLKR
                     NRAGRATFLPLTTIKARTISSQNQDAITVSPGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDAVEHARAAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     EIAADEASLRSEEAALKTLQDQMATLTERLEVIKSQGEQARIQEQGLSLAYQQTSQQV
                     EELETLWKLQEEEIDRLSEGDWQADKEKCQDRLAAIASDKQNLEAEIEEIKSNKNAIQ
                     ERYQNLQEELAQARLLKTELQGQKRYEVADIERLGKELDNLDFEQEEIQRLLQEKVDN
                     LEKVDTELLSQQAEEAKTQKTNLQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRYLQSQLTDQYQISYTEALEKAHELENLNLAEQEVQDLEK
                     AIRSLGPVNIEAIDQYEEVHNRLDFLNSQRDDILSAKNLLLETITEMNDEVKDRFKST
                     FEAIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            51557..52351
                     /locus_tag="VQ664_000214"
     CDS             51557..52351
                     /locus_tag="VQ664_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET2788456.1"
                     /translation="MTIKLVATDMDGTFLDGNGRFDMDRLKSLLASYKEKGIYFAVAS
                     GRGFLSLEKLFAGVRDDIIFIAENGSLVEYQGQDLYEATMSRDFYLATFEKLKTSPYV
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEAGETWVNDNVPGVKAMTTGFESIDIVLDYVDKGVAIVELAKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKDQSVIAYMEGL"
     gene            52351..53169
                     /locus_tag="VQ664_000215"
     CDS             52351..53169
                     /locus_tag="VQ664_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET2788457.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKATLKAASDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGHEDEYTITFNGGLVQKNTGEILDKTVFSYDDVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISPELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGIDQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKAAANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            53173..54393
                     /gene="ftsY"
                     /locus_tag="VQ664_000216"
     CDS             53173..54393
                     /gene="ftsY"
                     /locus_tag="VQ664_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HET2788458.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVEEVS
                     QEEAVLEESQDSEPAVGVSQEEIEELPEEEKLEHEGTIEENNSEVLEAERPQTEETVQ
                     EKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEELEELLIMSDVGVQVASNLTEELR
                     YEAKLENAKKPDALRRVIIEKLVELYEKDGSYDESIHFQDNLTVMLFVGVNGVGKTTS
                     IGKLAHRYKRAGKKVMLVAADTFRAGAVAQLAEWGRRVDVPVVTGPEKADPASVVFDG
                     MERAVAEGIDILMIDTAGRLQNKDNLMTELEKIGRIIKRVVPEAPHETFLALDASTGQ
                     NALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAIREELNIPVKLIGFGEKIDDIGEF
                     NSENFMKGLLEGLI"
     gene            complement(54439..55926)
                     /locus_tag="VQ664_000217"
     CDS             complement(54439..55926)
                     /locus_tag="VQ664_000217"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HET2788459.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYQSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATASKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPAIFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRSVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVGASWKLIDRIEELWA
                     ENGAPLHDYKAGSMGPQASFDLLEKFGAKWTWQPDIAYRQDGRFE"
     gene            complement(56075..56815)
                     /locus_tag="VQ664_000218"
     CDS             complement(56075..56815)
                     /locus_tag="VQ664_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET2788460.1"
                     /translation="MAKLKIDVNDLHKHYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEELGMELLEKVGLADKANANPDNLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            complement(56815..58980)
                     /locus_tag="VQ664_000219"
     CDS             complement(56815..58980)
                     /locus_tag="VQ664_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HET2788461.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALAEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
     gene            59153..60106
                     /locus_tag="VQ664_000220"
     CDS             59153..60106
                     /locus_tag="VQ664_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2788462.1"
                     /translation="MKNKRIFKDFQASKMNLNLYTSPLLAFVFVFIGEFVAYTLYGIS
                     LLALIGLARNFGEAGQNLASYLQTLHQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENCLSNLLKGFSLGLALFLLTLLSLVVLGQYRLESIHLNPYYLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSGLTPLS
                     LVNLFLFGVAMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM"
     gene            60183..62171
                     /gene="uvrB"
                     /locus_tag="VQ664_000221"
     CDS             60183..62171
                     /gene="uvrB"
                     /locus_tag="VQ664_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HET2788463.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAIAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTIGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            62181..62744
                     /locus_tag="VQ664_000222"
     CDS             62181..62744
                     /locus_tag="VQ664_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2788464.1"
                     /translation="MIYLRKLKREDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKQTRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLGLTTWSGNLGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKTNDGYYQINGNS"
     gene            62710..63198
                     /locus_tag="VQ664_000223"
     CDS             62710..63198
                     /locus_tag="VQ664_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2788465.1"
                     /translation="MTVIIKSMETPEEIEGKPLVHWQTWREAYDGLLPAEFQETMTLE
                     RCRFFSQKYPENTLIAMDGMKVVGFISYGNFRDETIQAGEIIALYVLKDYYGKGIAQK
                     LIKAALIALNHFSEIFLWVLKDNKRAIAFYQKMGFTFDEQEKILELGKPIKEKRMVFY
                     SK"
     gene            63271..63738
                     /locus_tag="VQ664_000224"
     CDS             63271..63738
                     /locus_tag="VQ664_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HET2788466.1"
                     /translation="MSRAQLTILTNICLIEDLEAQRVVMQYRAPETNRWSGYAFPGGH
                     VENGESFAESVIREIYEETGLTIQNPQLVGIKNWPLDTGGRYIVVCYKATEFSGTLRS
                     SDEGEVSWVQKDQIPNLDLAYDMLPLMEMMEASDKSEFFYPRRTEDDWEKKIF"
     gene            complement(63735..64250)
                     /locus_tag="VQ664_000225"
     CDS             complement(63735..64250)
                     /locus_tag="VQ664_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HET2788467.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHEVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFKPLSELTDGVHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(64262..64789)
                     /locus_tag="VQ664_000226"
     CDS             complement(64262..64789)
                     /locus_tag="VQ664_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET2788468.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGSLYLQKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
     gene            complement(65067..65630)
                     /locus_tag="VQ664_000227"
     CDS             complement(65067..65630)
                     /locus_tag="VQ664_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET2788469.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
     gene            complement(65614..66165)
                     /gene="coaC"
                     /locus_tag="VQ664_000228"
     CDS             complement(65614..66165)
                     /gene="coaC"
                     /locus_tag="VQ664_000228"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HET2788470.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLTLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLIAPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETIDEKTL"
     gene            complement(66177..66866)
                     /gene="coaB"
                     /locus_tag="VQ664_000229"
     CDS             complement(66177..66866)
                     /gene="coaB"
                     /locus_tag="VQ664_000229"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HET2788471.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLSAGHEVC
                     LITTKRALKPEPHPNLSIREITNTKDLLIEMQERVQDYQVLIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISADQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            67096..68766
                     /locus_tag="VQ664_000230"
     CDS             67096..68766
                     /locus_tag="VQ664_000230"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HET2788472.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELEIDQRR
                     ILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAVL
                     KELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNALSVQEKIEK
                     IVTEIYRGSKVNFEKKAQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
BASE COUNT        20966 a        12356 c        15065 g        20521 t
ORIGIN      
        1 ttagaagagc tttcacaagc ttatccagat gattatcttt tactcgttat ggacaatgct
       61 atatggcata aatcaagtgc cttaaagatt ccgactaata ttggctttgc atttattcct
      121 ccatacacac cagagatgaa cccattgaac aagtgtggaa agagattcgt aaacgtggat
      181 ttaagaataa agccttttaa actttggaag atgtcatgaa tcaactccaa gatgttatac
      241 aaggactgga gaaggaggtg ataaagtcca tcgttaatcg gagatggact agaatgcttt
      301 ttgaaagcag atgagtataa gtcctcgttt tgaagccttg gaacaggcca ttgcctccaa
      361 agatttggaa aaagtccgag aagcttttaa gaaaatgaat tccacttgga ccatcaatga
      421 aagtgtggtt cgtgacaata gtacagctca ttatggacgt gttgaaacag ctatttcctt
      481 cctgcctagt agcatggaaa ccgaacctac agatgagtct ggaacatgaa aacagcagtt
      541 gatttcaaga aacaaaaaag aacagtcgaa actgttcttt tatcattatt tgagaccgta
      601 ttttttgttg aaacgatcca cgcgtccatc tgcttgagtg aacttttgac gtccagtgta
      661 gaatgggtgt gagtctgatg aaatttccac acggatcaat gggtaagttt cgccttcgaa
      721 ctcaactgtt tcgttagagc gttttgttga accgctaagg aattggtaac cagtagttgt
      781 gtccatgaag acaactgggc gatattctgg atggatatct tttttcattt tgcaatattt
      841 cctttctgcc atggtctctt tgcgagccat agattgttac catactagtc tatcagattc
      901 tgaaaagttt ggcaagtatt ttatcagttt ttaagcaagt tttttaactt ttggtagatg
      961 atttcatttt cttctaggct ataggaatta gcaccacttg ctagagggtg gcctccacca
     1021 tcatgctcct tggcgatttc attgatagga tggattttac tgcgtaagcg aacgcggtag
     1081 tggccatcag cctgttccac aaaaattccc cagagactaa cactatcaat acgcccaggt
     1141 gcacctacaa tggccgcagt ttcagcatcg gttacattgt attgtttcaa gattttctga
     1201 ctcaggataa cgcgagcagc accattttca tccacttcca gatggtcgta gatgtagcct
     1261 tgcagtttag caattttgta gctcatagtg tccattttgc gagtgagagc cgcaaagtca
     1321 aagttatgtt ctctcaaata agcagccagg cgaagagtcc gtgcagtggt agaagggtag
     1381 aggaagcgac ctgtatcacc gacaattcct gcaaagagca actcagcatc gcgatctgcc
     1441 aaggctagtt gggttgtttg ggcaaatagg gtaatcatct cgctagcgct acttgaacta
     1501 gtatcgaccc aagacaggtc accgtataca tcatcatttg gatggtggtc aatcttaatg
     1561 agaaaatcac cttgactata gcgcttatca tcgatacgag cagtattagc tgtatcacag
     1621 acgatgacaa gtgcgccttg gtaggctcta tcttcaacaa gatccatctc agccatccaa
     1681 gtaagagttg gttcatcaaa accgacggct ttgatggttt tttctgggaa atgatgttcc
     1741 agcaaggctt tcaatcccac ctgacttccc aaggcatcag ggtctggttt catatgacga
     1801 tgaatgataa tggtgttgta ttctttaatt ttttctaaaa tttgttggca aatctccata
     1861 aataacctca attctttctc atttcattgt agcacaagaa tttttatttt taaaatgaaa
     1921 aagatgtgat ataatggaga aagataaatt gaggaggacg atatggcatt agcaaaaatt
     1981 gtatttgcca gtatgaccgg taataccgaa gaaattgcag atattgtagc agacaaatta
     2041 cgtgacttgg gcttggatgt tgatgttgat gaatgtacaa ctgttgacgc ttcagacttc
     2101 ttggaagcag acatcgctat cgttgcgacc tatacttatg gtgatggtga attgccagat
     2161 gagatgatgg acttctacga agacctagca gatctcaact tgaatggcaa aatctacgga
     2221 gtggtcggct caggagatac cttctacgat gaattctgta aggctgttga tgactttgac
     2281 cgtgtctttg tgtcaacagg agcagaaaaa ggttcagagt gtgttaaagt tgatctttct
     2341 gccgaggaag aagatattga acgcttggaa caattcgcag aagaattggc tgctaaagta
     2401 ggataagcat aaaagtgcgc tgatgtaatc aatcagtgca tttttcttat cgagagttgg
     2461 gattttacta gcctaattga tggctttttg atacaataat tcaaataaag gaggagactg
     2521 tatggattta gatattattc gtcaagaaat cgatcaaatc gacgaccaaa ttgtcaaact
     2581 gttagaagaa cgaatgcatt tagttgaggg ggtggttgct tataagaaag cttcaggtaa
     2641 accgatttta gatactaaga gagaagaagt tatttttgaa aaggttagga gtcgtgtaga
     2701 ggacaagcgc tatcaggaga ctattgtcgc gactttttcg tacatactca aacgttcgcg
     2761 tgattatcag gatcaaaata tcaaatgaaa aaagaacaat tttatccgct aggaattttt
     2821 ctagctgcta tgttgggcgg acttgtccga tatctagttt ccacctggtt accagccagt
     2881 ccagactttc cttggggcac tctctttgtc aactatctgg gaattttctg cttgattttt
     2941 cttgtcaagg gctatctggt ctataagggg actagtaagg gcttgatttt agcactgggg
     3001 acgggttttt gcggaggttt aacaactttt tccagcctaa tgcttgatac tgtgaagctg
     3061 cttgatacag ggcgttattt tagtttagtc ctgtatttgc ttttgagtat cggtggaggc
     3121 ctgcttttag cttactattt ggggaggaag aaatggtaat cgtctatctt gcaatcgcct
     3181 gtggcttggg agcactcgta cggtatttct tttctcgcta taatcaagct tctaaattgc
     3241 cactcggaac gctcatagct aatcttttag gttgtttttt aattggagta ttctacaatc
     3301 atgtagagtc taaggaagta tatgctattc tagcaacagg attttgtggc ggtttaacaa
     3361 ctttttcgac cttgaatgac gaacttcaaa gactgctaag tgataagaag gtcttttatt
     3421 cttacctgac tttgacttac ataggtggtt tggttgcgat ttttttagga attttgctat
     3481 aaatttcttt actttttttt agaaatttgg taaactatat cttgtgtgta atggacgcac
     3541 aaaaatacag tttatccgct gaggaagatt cctcaagatt gacaaagata ggagaataaa
     3601 atgaatccat taatccaaag cttgactgaa ggtcaacttc gtacagatat cccatcattc
     3661 cgtcctggtg acactgttcg tgtacatgcg aaagttgtcg aaggtaaccg tgaacgtatc
     3721 cagatttttg aaggtgttgt tattgcacgt aaaggtgctg gcatctctga aaactacaca
     3781 gttcgtaaaa tctctaacgg tgtaggtgtt gagcgtatct tcccaatcca cactccacgt
     3841 gttgaaaaaa tcgaagttgt acgttacggt aaagtacgtc gtgcgaaatt gtactacttg
     3901 cgtgctcttc aaggtaaggc agctcgtatc aaagaaatcc gtcgttaatt cgactaaaaa
     3961 actctgcttt ttcagcagag tttttatcta gctcccttag ttcaatggat ataacaactc
     4021 cctcctaagg agtagttgca ggttcgattc ctgcaggggg catgtaatta gatatcaaag
     4081 aagtttgtca aagagtcttt gatattaaaa gaacgcataa tataggggat tgtctccata
     4141 atattatgcg ttttattatt gaaaaatttg ggcaatcatc agataaaatt gagactatat
     4201 cgagtatata aatgtttgta tagtcaattt attcaaaatc gtcaagttct aaattattta
     4261 aaggactata acattcatat ttctttaagt aattgtttat ttcttcagca gtggaacgag
     4321 gtaaattaac tcttaaatag tcaatatctt ccttagataa aaaatgattt gcattcaaaa
     4381 ttgagaagcg aaataatgct tcatcaaaag caaaatcata atcgtcatca gataatgatt
     4441 ccattaatgt ttgaatatgt tttagtgagt agtcaggtat cgaatcggga taatatactg
     4501 gataatcagt ggctgaaaaa ttgttttcta atcctgaaat agtaattatc aaagattcta
     4561 tgtaatatat taaagcatgt ttaatattac cttcttgttc caaatgtctt ccctgagcct
     4621 ttcgtgtgtt agataagcat ccaaaatctc ctgatacagt attcctatga gcttgtttat
     4681 ttaagagact ccattttata tcaccaaaag ttgctttaaa agagatattg tttttttctt
     4741 tacaataatc ttccatactt atgtctttat catagtatgc tttgatatag tcactatgtt
     4801 cgataataag attttgtgct tcttttgtta gtttaaattc gaacggaata tctaaattgt
     4861 caatgttaac attattaatt attcttgtaa ttaattctgc tttttttcca gaagtagcta
     4921 aattatgttt agataatata gtttttaatt ctactactgt aagatatgat aaagtcttat
     4981 ttttagtgaa gtatcctaat ttgtataatt gattgtgtgt agattcaggg tcaatttgaa
     5041 gagagtattt aaaatatctt gggaaattat aatttctccc tgttttttga gtccaatcta
     5101 tgagtatgag ttgcccagga gtaaggccac attctaattc gtttaggtaa aaattgttac
     5161 aatcagaatt tgtgtctcta ttatgattat tttgttttaa attaaatagt ttgctaaaaa
     5221 aattcattgg attttattgc taatcaattc ttattgaaaa atgatacttt tacagtaccc
     5281 atgttcggat ggcatgggca acgccggatt cgtcatttgt tttggtgatg tatttggcga
     5341 tttttttgat ttctggattt ccattttcca tgacaacggg gtttccaacg acttccagca
     5401 tgggacggtc attttcttca tcaccgattg ccatggtttc atctttggtc aatccgagtt
     5461 tttcagccaa gtgagtaatg gctgaaccct tgtctacatt ctttttaagg agttcgaggt
     5521 agaaaggagc agatttgttg atggagtagc gctcgtaaaa ttctgctgga attttttcaa
     5581 tcgcagcatc gagaatttct ggttcatcga taaacataca tttaacaatt tctttgccag
     5641 ccatttcttc aggggtacgg tagaagatag gcatgctgac gagggttgat tcgtgtacag
     5701 tgtattttcc gatattgcga tttgcagtat agataccgtc cttggtaatg gcatgcatgt
     5761 ggacaccgag cttgcgactg aggaattcca tatccagata atcctcatag gtcaaggatt
     5821 cgctgataat ctcatggcca gtagcagttt cttggacaag ggcaccattg aaggtcacca
     5881 catagtcacc ttggtctctc aactgcaagt cgtccagaag tttggcaaca cctgcgatgg
     5941 ggcggccagt tgcaatcacg actttgacac cagcttcttt ggcatcttgg atggcagaaa
     6001 agacttcagg agtgatttcc ttttggctgt tgactagggt tccgtcaata tcgacggcaa
     6061 ttagtttaat actcataaaa ttcctcttct agtttttatt tggggtaaaa tgatcgttct
     6121 caatcaagtg taaaaattgc tgggtaatgc ttgcgaagat gctgttttgg tctaacattt
     6181 ctttagggaa atagaaacga ttatctccgt ggcgactgcc agcaagggat tggacgatag
     6241 gagacaggct agagagttcg gccagttctc catttttttg taaaatctca atctgtgtcc
     6301 gtggattttg agattcggga cgatagatat cataagggag gtcaaagttc ttatgaatgg
     6361 cagtatagta gtcgggatca aagccgatgt cctcaaccaa ttttctcatg ctagtaagtt
     6421 gatcttggtc ctcttgtgaa aaggtaatgg atttaaagac cttgcggttg acaaagcgtt
     6481 gagataaatc tgcaagaatt ttgtcaggac tagtcatcca aagctggaag taggtattca
     6541 tcacgccatc atccagagcc agatagtcag tcaaggtcac atttttttcg aagaaaggca
     6601 ggagatgtgg ggaagttcgt gcaaagaaat tcttgtcctc agggtagagt tccttggcgc
     6661 gcttgagaag attctgtagg agaacttcca tggcgcgtgt tgctgggtgg aaataaacct
     6721 gcatgtacat ctggtagcga ctgaggacgt agtcttcgat ggcgtgcatg ccattgcgct
     6781 gaaaggcgat accattttcg acaggacgaa tgactcggag gatgcgagtc aggtcaaatt
     6841 ccccatagga tgctcctgta aaataggagt cgcgcaagag atagtccatg cgatctgcgt
     6901 caatctgact agaaatgagc tgcacgacct gcttattagg ataggtatgg tcaatgacac
     6961 tggccacctt ttctgggaaa tcaggtgcca cttgtagcag gacttggtga atctctgtct
     7021 caggattttg aataatctcc tgagtaatgg cttcatggtc tgtatcaaag agattttcaa
     7081 aagtatggga gtaggcacca tgcccaaggt cgtgtaggag agcagcggtc acggtcaaga
     7141 gagactcggc aggattccat tcctcaggat atttttcttc gaaaatctct gtgatgcgtc
     7201 gtgcaatttc atagactcct agacagtgag agaagcgact gtgttctcca ccgtggaagg
     7261 tataactgga agttcccagt tgtttgatcc ggcgcaaacg ctgaaattct tttgtattaa
     7321 tcaagtcata gatgatttga ttattgacat ggatgtagtt gtgaactggg tcacggaata
     7381 ctttttcgtt catatgacca ttatagcaaa atcctgctct ttttggtaaa atagtaggac
     7441 aagagacaag aaagagggcc tgatgtgaag attcggatgc gaaatacaat tcagtttgat
     7501 gagcagttgg aagtgattga ccagctttat gatgtggaag tgcatgaaaa aggagattat
     7561 agctacctgc ttttctataa tgaggaaaag gaaaaagtag tgattaaatt tcatggtcaa
     7621 gaacttatga tgagccgatt ttctaatccc aagaccatta tgcgctttct aaaggatagc
     7681 gatagtttag cctatattcc tacacctatg ggcatgcagg agtttatcat ccaaacgagc
     7741 cattatcaag ttgataggca aaagattgaa ctagattatc aactacaaaa tcaagaggga
     7801 catccttttg ccagctatca attggaaatt acttggggct aggctcatgt ctttttcaaa
     7861 tttagctatc tatcttcttg gatcggcttc ctagtgtggt agattaggct aatttttggt
     7921 ataataaaag ttatggaaat cgaaaaaacc aatcgtatga atgcgctctt tgaattttat
     7981 gcggcgcttt tgacagataa gcaaatgaat tatatcgagc tctactacgc tgatgattac
     8041 agccttgctg aaattgccga ggagtttggt gtcagtcgtc aggctgtcta tgacaatatc
     8101 aagcgaacag aaaagattct ggaagattat gagatgaaat tgcacatgta ctcggactat
     8161 attgtccgca gtcagatttt tgatcagatt ttggagcgct atcccaagga tgactttctg
     8221 caggagcaga tagaaatttt aacaagcatt gataatagag aataagagga agaaaaatgg
     8281 catttgaaag tttaacagaa cgtttgcaga acgtctttaa aaatctacgt aaaaaaggaa
     8341 aaatctctga atctgatgtc caagaggcaa ccaaagaaat tcgcttggcc ttgctcgagg
     8401 ccgacgttgc cttgcctgtt gtaaaggact ttatcaagaa agttcgtgag cgtgcagtcg
     8461 ggcatgaggt cattgataca cttaatcctg cgcaacagat tattaaaatc gttgatgagg
     8521 aactgacagc cgttttaggt tctgatacgg cagaaattat caagtcacct aagattccaa
     8581 ccatcatcat gatggttggt ttacaagggg ctggtaaaac aacctttgct ggtaaattgg
     8641 ccaacaaact caagaaagaa gaaaatgctc gtcctttgat gattgcggcg gatatttatc
     8701 gtccagctgc cattgaccag cttaagacct tgggacaaca gattgatgtg cctgtctttg
     8761 cacttggaac agaagtacca gctgttgaga ttgtacgtca aggtttggag caagcccaaa
     8821 ctaatcataa cgactatgtc ttgattgata ctgcgggtcg tttgcagatt gatgagctcc
     8881 tcatgaatga gcttcgtgat gtgaaagcat tggctcaacc aaatgaaatc ttgcttgtcg
     8941 ttgatgctat gattggtcag gaagcagcca atgttgcgcg tgagtttaat gctcagttgg
     9001 aagtgactgg ggtcatcctt accaagattg atggcgatac tcgtggtggt gctgctctgt
     9061 ctgttcgtca cattactgga aaaccaatca agttcactgg tacaggtgaa aagattacgg
     9121 acattgaaac cttccaccca gaccgcatgt ctagccgtat ccttggtatg ggggatatgc
     9181 tcactttgat tgagaaagct tctcaggaat acgatgaaca aaaagccctt gaaatggctg
     9241 agaagatgcg cgaaaacacc tttgatttta atgatttcat cgatcaatta gatcaggtgc
     9301 aaaatatggg gccgatggaa gacttgctca agatgattcc aggtatggcc aacaatccag
     9361 cccttcaaaa catgaaggtg gatgaacgcc agattgctcg taaacgtgcc attgtgtctt
     9421 cgatgacacc tgaagagcgt gaaaacccag atttgttaaa tccaagccgt cgccgtcgta
     9481 ttgctgctgg ttctggaaat acattcgtcg aagtcaataa attcatcaag gactttaacc
     9541 aggctaaaca gctcatgcag ggtgttatgt ctggggatat gaataaaatg atgaagcaaa
     9601 tggggattaa tccaaataac cttcctaaaa atatgccaaa tatgggagga atggatatgt
     9661 ctgcccttga aggaatgatg ggacaaggcg gtatgcctga cttatcagct ctcggaggag
     9721 caggaatgcc agatatgagc cagatgtttg gtggcggttt gaaaggtaaa attggtgaat
     9781 ttgccatgaa acagtccatg aaacgtatgg ctaacaaaat gaagaaagcg aagaagaaac
     9841 gcaagtaaga caagagattg atgcaaatct catttgatga gaaaataaag taaaaatttc
     9901 tatgataaaa cgtacagtat caaggtttta gaatatctga tattatacgt tttttgattt
     9961 taataatttt gttaagacac ttttattatg gtatacgaaa aatccactca gctgtctgag
    10021 tggattaggt gtatttagac tcttagtctt tattttcgta tggcaagatc aagttcaaga
    10081 tgattcctgt catggctgaa agggcagtac ctgaaagtgt aactggacca agtttaagga
    10141 tagctcctcc aagtccaaga accaacatag cacttgcgat gatgaggttt cgcatttgag
    10201 cgaaatcaac acgttcttta atcaagactt tcaaaccatt gctggcgata accccataga
    10261 gaaggattga cataccacca agtacagcgt ttggaatagt tgaaatcaag gcagtgaatt
    10321 taccaaggaa gctgagggca atcgcgatga aggcagcgtt acggataact gagacagaag
    10381 cgatacgagt cataccgata acccctgtat tttctccgta agttgtattg gctggtccac
    10441 caaggaaggc agaaacagaa gttgcgatac cgtcaccaag aagagtacgg tgaagacctg
    10501 gttcttttaa gaattgacga ccacagattt gacccaaaac agtatggtct ccgatatgtt
    10561 cagaaattgt tacgatagcg attggcaaga tagcgatggc ttctggacca aagtaaagat
    10621 tgtactcttt aaaggcacca cctgtgctaa atggcaagta gaaaccagga atttcgaacc
    10681 agttggcttt aagaactggt gtaaagtcaa ccaagccaag agttagtgcg aaaaggtaac
    10741 caccgataat ggcaaagagg aatggaatga ttcgtaggaa gccttttcct tttgtattga
    10801 taaaggcagc aattaggaaa gtaacaacgg ctaccagagc atttttccaa tttccgtctg
    10861 ctacaagacc tgcattggta acagctgaac ctgcaagtcc aagaccgata acgatgatca
    10921 taggaccgat aatgattggt ggcaagagtt tatcaatcca ttttgttcct acaaatcgga
    10981 tgctggtagc aacaaggaca tagaccaaac cagtcaagat aacccctgtt tgggcagcag
    11041 atacatcccc ccccatttct ttcatagcca gtgacatagc tgtgataaag gcaaatgaag
    11101 aacctagata aactggaact ttaaaaccag tagcaatcat gtagatgagt gttccaacac
    11161 ctgaagcaaa aagggcaaca gatacaggca ttcccaaaat caatggtacc aagatggtcg
    11221 caccaaacat ggcgaaaacg tgttggaaac taaggagaat tccttttcca gccgaaggac
    11281 gttggtcaac gtctagtaac aaatcaacag ttgattcttg tttcatataa acctcacttt
    11341 tgggcatcaa aaaagagccc attattttac agcaataggc cctcagagta agacttcttt
    11401 aaaatttaga ttttaaagag ttttaaatat ttctgcgtct tcgtcacctc acgggatgac
    11461 attaaaaacc tttgcttagg atagtatagc agaaaaaaat gattttgtaa atcatttttt
    11521 cccgagccta gaaataaaag agcgaggctg attttgtaaa tcattttttc ccgagcctag
    11581 aaataaaaga gcgaggctga ttttgtaaac atttgtttac taaaaaattt aaagtgggcg
    11641 tttatttggc ataccagcct tacgcggata tttatttggt gtttcttttt tcttttctac
    11701 cactgtgata tagcgcggat ctctattcgg tagggcgtag ctgagattgt cttcgacctt
    11761 actaaaaagg agattgaggg cattcttagc ttctaataat tcctcaggcg cattgctggc
    11821 cttgagtgcc aatagttttc caccaacctt aaggtaggga atggtcaatt cagataggac
    11881 ctgcatacgg gcaaccgcac gagctgttac aaaatcatat tgagcacgga agttcttgtc
    11941 ttgggcaaaa tcttcggcac gtccgtggta gaaatgaact ccgttcaaat ccagttcttg
    12001 agccaagagt tgtaggaagt tgatgcgctt attgagtgaa tcaataatgg tcacatctaa
    12061 ctccggatag agaattttca ttggtagact aggaaatcct gccccagccc cgatatcaag
    12121 aagtttgata gtttcattgg gaatcaaacc ttgaagaatg ggtgcaatcg aatcgtaaaa
    12181 atgtttgaga taaacttctt ccttgtccgt aatcgccgtc aaattaatct tctcattcca
    12241 ctcgaccaag agctcaaaat aacgttcaaa ttgttctttt tgctggtccg aaagtggaag
    12301 attctgctcg gcaagcaagt tgtaaaatgt ttttggtttc atagttattt ccttctttag
    12361 tatcatctta ttttaccaca atcatagaaa atttgatata ctggtactaa tctaaaagca
    12421 gaaaggactt atattatgac ttggattatt cttggagtta tcgctcttat tgttattttt
    12481 gtgattgtta gctataacgg tttggttaaa aattgtatgc aaaccaagga ggcttggagt
    12541 cagattgatg ttcagttgaa acgtcgaaat gacctcttgc caaacttgat tgagactgta
    12601 aaaggttatg ccaaatatga aggttctacc cttgaaaagg tggcagaact acgtaaccaa
    12661 gtggcggcag cgacttcacc agcagaagct atgaaagcca gtgatgccct cactcgtcag
    12721 gtttcaggta tttttgcagt tgcagaaagc tatccagatt tgaaagctag tgctaacttt
    12781 gttaaattgc aagaggagtt gacaaacaca gaaaataaaa tttcttactc tcgtcaactc
    12841 tataacagtg ttgtcagcaa ctacaatgta aaattagaaa ctttcccgag caatattatc
    12901 gctggaatgt ttggatttaa agcggcagat ttccttcaaa catctgaaga ggaaaagtcg
    12961 gttcctaaag ttgattttag cggtttaggt gactaagatg ttgtttgatc aaattgcaag
    13021 caataaacga aaaacctgga ttttgttgct ggtatttttc ctactcttag ctcttgttgg
    13081 ttatgcggtt ggttatctct ttataagatc tggacttggt ggtttggtta tcgcactgat
    13141 tatcggcttt atctacgctt tgtctatgat ttttcaatcg acagagattg tcatgtccat
    13201 gaatggagcg cgtgaggtgg atgagcaaac ggcaccagac ctctaccatg tagtggaaga
    13261 tatggctctg gtcgctcaga ttcctatgcc ccgtgttttc atcattgatg atccagcctt
    13321 aaatgccttt gcgacaggtt ctaatcctca aaatgcggct gttgctgcga cttcaggtct
    13381 actagctatc atgaatcgtg aagaactaga agctgttatg ggacatgaag tcagtcatat
    13441 tcgtaattat gatatccgta tttcgactat tgcagttgcc cttgctagtg ctatcaccat
    13501 gctttctagt atggcaggtc gtatgatgtg gtggggtgga gcaggtcgca gacgaagtga
    13561 tgatgaccga gatggaaatg gtcttgaaat cattatgcta gtggtttccc tactagctat
    13621 tgtactggca cctctcgctg caaccttggt tcagctcgct atttctcgtc agagggaatt
    13681 tctggcagat gcatctagtg tcgagctgac tcgcaatccc cagggaatga ttaatgccct
    13741 agataagttg gacaatagca aacctatgag tcgccacgtc gatgatgcta gcagtgccct
    13801 ttatatcaat gatcctaaga aaggtggggg gttccaaaaa ctcttttata cccacccacc
    13861 tatctcagaa cggattgaac gtttaaaaca gatgtaaaag aatccagagg tcgtctctgg
    13921 atttttgcta tgttgcaaat ttataaatct tctaaattaa ctagcttcaa accgtgttct
    13981 gtcatgcgat agatgatcga gcagacttct tttaagaaac gacggtcatg cgaaacagtg
    14041 atgagaccgc ctggataggt tgcaaagagt tttctgattt ggggttgaga agtgggagaa
    14101 aagtttcgtg tgggttcatc cagcaggaga aagtttggtt tgcgcagaac tagatccaaa
    14161 agcaggagtt ttccctgttg tccgccagat aaggagcgaa tttgatgctg catttctgga
    14221 taactgaaat tgagactggc taggtgagat tggattttct gaagttcctc tttttcccca
    14281 gttttgctga tataagctat tgaggataaa tccaattgca gttttttgtg gtaatcttgt
    14341 ggcataaaac caagtgaaat ctctctttta tcattcagaa gttgctgtaa tttggctaac
    14401 agagttgatt tcccaacacc atttgggccg atgataccga ttttttcttg gccacggaca
    14461 gttagttgca gttcctgagc caaaacacgg tcgtcaatgg acaaattttc tttttccagt
    14521 tggactaaga ctttagaagc tggtaatggt tggatgtctg aaaagaaaag ttggatttgt
    14581 tcctcttcaa gtggcttttg agtcatggac tgagctgtct tttcgtagcg tttttcttgt
    14641 gagaggacag ttttcatctt tttagccaat aggcgaccgg cagtactatc tttggtagct
    14701 cgaagcgcag tttctacatt ttgcttaact ctccgatgtt tttccatggt tttatcgtag
    14761 gctctttggt tgttagcagc ttgctgactt tgtttggcaa aattagcctt tctctgctca
    14821 ctatagctat catagtctaa atgctctact agcgtttccg cttctttacg gtgtttgacc
    14881 agtcgcaagt gaacaatagt gtctgccgtt tcagaaagaa agtcttcatc atgggaaatg
    14941 aaaataacgg tttgcctggt cttttgaatc tggcctttta gccaatcaac tgtctcaagg
    15001 tctaggtcat ttgaaggttc atctaaaaat agaatctcaa agggtttggc taactcatgg
    15061 ataagctgaa ttttcaaagc ttcgccccct gatagattgc caatctcttg gtcacttgcg
    15121 aaacgattgc tatcaaaatg caattcctcc gccaaacgat agaggatact gtagtctaaa
    15181 tcaatagaat ctaaaaagaa gtagtcgtgt aaagttttct tttttaggtc ctcagggact
    15241 ttttgaggaa tgtaggccag tgactgataa tcagactgga tgtctccctt gatagtgaaa
    15301 tcagacaaat cttcccccat taaagtttta agtaaggttg atttaccatt tccttcttcg
    15361 ccaataatag ctaccttttc cccgtcttgt atggtcatgc ttaggtcaga gacaaggtct
    15421 cgtaaatctt tgttttgtgt gatggtcagg tgattgattt ttatcatact attgcccttt
    15481 ctagaatgtc gatagtgcat aacaaaaagc tctactttac ctagtagagc ccaaagtcta
    15541 tgtcaaaaaa actctattaa catgccagaa aaagagcata aaagagcaca caaaaagaga
    15601 caaaaacaag atctactaaa taaaggttct ttatttgata gacttagttg ttcatgtctc
    15661 ccttacctcc gagtattagt atctttatac tatactttta aggaaatttt gtcaacagaa
    15721 aactggaaat tctatgctct aaaatccaaa aacaggtcca tagagactta gtacgtgttt
    15781 gacatgctcg taatggattt tatcatagtt tcgccaagca gtgcgtgctt gatcgtttag
    15841 ttttaggcta cccagtccaa tcagaggact ggtgggttgg taaaatttct caagatcaat
    15901 taagatactg ttgttcaact tttccgtttt tttgagctct tgcatagtag tgtttagcag
    15961 ctcttgtagt cgaatatcat ctgccgtacc ctgtttacag ttttggtagc ttttatttaa
    16021 cttggatagg agttgaatga gtttcttgtc ttccatgtct tccatatgag catcctcctt
    16081 gatctgatgt actctttccc tatagtatag cactaaaaaa taaaactgtc atagtaaata
    16141 tgttaaaatt ttgaatttta attacaaagt ttggtgtgct gatttgtagc cttttcatgg
    16201 tataatcaag agagtaaatc tttatggagg aagtatgaaa ttaaatattc aagaaattcg
    16261 taagcagtct gaaggtttga actttgaaca aacgttagat ttagttgatg acctgcgtgc
    16321 acgtaatcaa gaaattttag atgtaaaaga tatccttgca gttgggaaag tacaatatga
    16381 agaccgtatg tatttcttag attatcaact atcttatacc attgttcttg cttcgagtcg
    16441 cagtatggag ccagttgagt tagttgaatc ttatccagtc acggaagttt tcatggaagg
    16501 cgcaactaac cagctagatc aagaagtttt agatgatgac ttggtcttgc ccattgaaaa
    16561 tggggagctt gaccttgctg agagtgtatc agacaatatc ctgctaaaca ttcctatcaa
    16621 ggtcttgacg gctgaagaag aagctggtca aggatttatc tcaggaaatg actggcaaat
    16681 catgacagag gaagaatacc aagctcaaca agcagtaaag aaagaagaaa acagtccttt
    16741 tgctggctta caaggactat ttgacggaga tgaataatgg tcttgtcaaa aaaacgagca
    16801 cgaaaggtgc tagaagaaat cattgccctc ttcccagatg ccaagcctag tcttgatttt
    16861 accaatcatt ttgaactcct ggttgcggtc atgttatcag cccagacgac agatgcagcg
    16921 gtaaataagg ccacaccagg tctctttgtt gcctttccaa caccccaagc tatgtctgta
    16981 gcgacagaga gtgagattgc ttcacatatt tctcgcttgg gattgtatcg gaataaagct
    17041 aaattcctta aaaaatgtgc ccaacagtta ctagacgatt ttgatggtca agtccctcag
    17101 acacgtgaag aattggagag tttggcaggt gttggtcgca agacagccaa tgttgtcatg
    17161 agtgtaggat ttgggattcc agcctttgca gtggatactc atgtggagcg tatttgcaaa
    17221 caccacgata ttgtcaaaaa atcagcgacg ccacttgagg tggaaaagcg ggtcatggat
    17281 atcttgccgc ctgagcagtg gttagctgcc catcaggcca tgatttattt tggaagagcc
    17341 atttgccatc caaaaaatcc agagtgtgac cagtacccac aattatatga ttttagcaat
    17401 ttgtaagatg ctacattgaa actttttgct tgattttaag catgctttgt gctatagtaa
    17461 atgataacta aatattcctt taaacctgtc ccgtgaggca ggcaaggagc gcgataaagt
    17521 agaagggtga agtctatact gtttgcagta gggctcgctt ggctataaat ttcaagtctc
    17581 cttgtttaag gagacttttc tttttggagg tttgtcatga aaacaaaaga agttgtagac
    17641 gaattgaccg tcaaacgagc gattacgcgt attacttatg agattatcga acgcaacaaa
    17701 gatttgaata agatcgtctt ggctggtatt aaaactcgtg gtgtctttat tgcccaccga
    17761 atccaagaac gtttgaagca gttagaaaat ctttcagttc ctgttgtgga attggatact
    17821 aaacctttcc gtgatgatgt taaaagtgga gaagatactt ctttggtttc tgtcgatgtg
    17881 acagaccgcg aagttatctt ggtggatgat gtgctctata caggtcgtac catccgtgct
    17941 gctattgata atattgtcgg tcatggtcgt cctgcgcgtg tgagtttagc agttctagtc
    18001 gatcgtggac atagagaatt gccaatccgt ccagattacg ttggaaaaaa tatcccaacc
    18061 agtcgttctg aagaaatcat cgtagagatg acagaacttg atgaccaaga cagagttctg
    18121 attactgaag aagcttagaa agttaaagga gtagccatgt cagaaaatca acaagcattg
    18181 aaccatgtgg tgtccatgga agacctcact gtcgatcaag taatgaaatt gatcaagcga
    18241 ggaattgagt ttaaaaatgg agcccagctt ccctatgaag accatccgat tgtttccaat
    18301 ctcttctttg aggattctac acggacacat aagtcctttg aagtcgcaga gattaaactt
    18361 ggattggaac gacttgactt tgatgtgaag actagttcgg ttaataaggg tgagacactt
    18421 tatgacacca ttttgactct gtctgcttta ggagtggatg tctgtgtgat tcgccatcca
    18481 gaggtcgact actatagaga attgattgct agtccaacga ttacgacttc catcatcaat
    18541 ggtggagatg gttcgggcca acaccctagc cagagcttgc ttgatttgat gaccatttat
    18601 gaggaatttg gccactttga gggtcttaaa gttgctattg caggtgactt ggaccactca
    18661 cgcgttgcca aatccaatat gcagattttg aaacgcttgg gagctgaact ctttttcgct
    18721 ggacctgagg aatggagaag tcaagagttt gcagactatg gaaagtttgt aaccattgat
    18781 gaaatcattg atcaggttga tgtcatgatg tttctccgtg tgcaacacga acgccatgat
    18841 agtggagctg tattttcaaa agaagactat catgcccaac atggcttgac tcaagaacgt
    18901 tacgatcgtt tgaaagaaac agcaatcctc atgcacccag ctccaatcaa tcgtgatgta
    18961 gaaatagcag accacttggt tgaagcacca aaatcacgga ttgtccaaca aatgaccaat
    19021 ggtgtctttg ttcgaatggc aatcttagaa tccgtactag cgagtagaaa cgccaactaa
    19081 aacacaagac gttaaaagac gccagtgagc gtccacgaga ggtgaaaata tgacaaaaag
    19141 aattctagta ttagaagatg gcacagtttt tgaaggcaag gccttcggag cagatattga
    19201 tgtaacaggc gaaatcgtct ttaatacagg gatgaccggc taccaagaat ccattacaga
    19261 ccagtcttat aatggacaaa tcttgacctt tacttatcct ttggtaggaa attatggtat
    19321 taatcgtgat gattatgaat ccattattcc aacttgtaag ggagtcgttg tttttgaaga
    19381 agcgcgtaga gctagcaact ggcgcaacca aatgaccttg gatgaatttt tgaaagccaa
    19441 gaaaattcca gggatttcag gaattgatac gcgtgctctt accaagatta tccgtaagca
    19501 tggtactatg cgtgcaacct tgacccatgt tggggacagt atggaccatg tgacggacca
    19561 gctccaagca acagttttac cgacagacaa tatcaaacag gtttctacta aaacgtctta
    19621 tccagctcca ggagttggtt tgagcgtggt gctagtggac tttggtctca agcactcaat
    19681 cctacgtgaa ctttctaaac gcaactgtaa cgtgacagtt gttccttatt cgacaacggc
    19741 tgaagaaatt ctccatctca atcctgatgg agttatgttg tcaaatggtc caggtaaccc
    19801 agaagacgtt ccacaagcac tcgacatgat tcgcggtgta caaggaaaaa ttccaatctt
    19861 tggtatttgt atgggacacc aactctttgc aatggcaaac ggggctaaga cctataagat
    19921 gaagtttggc caccgtggat tcaaccatgc ggtacgtgaa atcgcaacag gacgagtaga
    19981 cttcaccagc cagaaccatg gttatgcagt cagccgcgag gatttgccag agcacttgat
    20041 tattacccac gaagaaatca atgacaagtc agtggaaggt gtgcgccaca gataccaacc
    20101 tgctttctct gttcaatacc acccagatgc agctcctggg ccacacgacg ctagctacct
    20161 atttgacgag tttatcgaga tgatggaagt ttttaaacaa tcaaactaag aatgagtaaa
    20221 agctcgtcgg agaatttatg taactgaaca tggacggaaa gctcagaatt tagagaaacc
    20281 aacttggatt gtcaatcctt ccttgatttc ctaaaattca atcgctttct agtcgtcctt
    20341 tgtatcttat ttaatgtcgc cctgagaggc gacgaataga aaggagaaga tacattgttc
    20401 gcggaagtga acacgcccta agaactgtgt gaaaaagata aacatcgtct tgacgctgaa
    20461 ggcgtctgcg ccgagtttcc tattttcact gtgttcttta cgggctttgt atcataaact
    20521 atgcctaaac gtactgatat tcaaaaaatt atggtgattg gttctggtcc gattattatt
    20581 ggtcaggctg ctgagtttga ctacgctggg actcaggctt gcttgtcgtt gaaagaggaa
    20641 ggttatgagg ttgttttggt taactcaaat cctgcaacca tcatgacgga caaggaaatt
    20701 gctgacaagg tttacattga accgattaca cttgagtttg tgacacgtat tcttcgtaag
    20761 gaacgtccag atgccttgct accaacactc ggtggtcaga caggtctcaa catggccatg
    20821 gaattgtcta aaaatggtat cttagatgag cttggcgttg aacttctggg taccaaatta
    20881 tctgccattg accaagcgga ggaccgtgac ctctttaaac aattgatgga agagcttgaa
    20941 caacccattc cagaatctga aattgttaac acagtagaag aagcagttgc ctttgcagcg
    21001 acaattggct acccagtcat cgttcgtcca gcctttaccc tcggtggtac tggtggtggt
    21061 atgtgtgcca acgagaaaga attgcgtgaa atcactgaaa atggtttgaa attgtcacct
    21121 gttacccaat gtttgattga gcgttcgatt gccggtttca aggaaattga atacgaagtg
    21181 atgcgtgact cagctgacaa tgccttggtt gtttgtaaca tggaaaactt tgacccagtt
    21241 gggattcaca cgggggattc cattgtattt gcccctgcgc aaaccatgtc agactatgaa
    21301 aaccaaatgc ttcgtgatgc gagcttgagc attattcgtg ccctcaagat tgaaggtgga
    21361 tgtaatgttc agctagctct tgatcctaac agcttcaagt attatgttat cgaagtaaac
    21421 cctcgtgtat cacgttcgtc agcccttgct tctaaagcga caggatatcc gattgctaag
    21481 ttggctgcca agattgcagt aggtttgacc ttggatgagg ttataaaccc agttacaggt
    21541 tcaacctatg ccatgtttga accagccctt gactacgtag ttgctaagat tccacgtttc
    21601 ccatttgaca agtttgaaaa gggtgaacgc cgtctcggta cacaaatgaa ggcgactgga
    21661 gaagtcatgg caatcggtcg taacatcgag gaatctcttc tcaaggcctg ccgctccctt
    21721 gaaattgggg tgcaccacaa tgaaatacct gaacttgcag cagtttctga tgatgccttg
    21781 attgaaaagg ttgtcaaagc ccaagatgac cgtctcttct acgtatcaga agcaattcgt
    21841 cgtggctaca cacctgaaga aattgcagag cttacaaaaa ttgatatctt ctatcttgat
    21901 aaactcttgc atatctttga aattgagcaa gaattgggtg ctcatccaca agatctagaa
    21961 gttttgaaaa cagccaaact taatggtttt tcagaccgta agattgctga actctgggga
    22021 acgactgatg atcaagttcg ccaacttcgc ttggaaaaca agattgttcc agtttataag
    22081 atggtagaca cttgtgcggc agagttcgac tccgaaacgc catatttcta ttcaacctat
    22141 ggttgggaaa atgaatctat cagatctgat aaagaatctg tacttgtcct aggttcaggt
    22201 ccaatccgta ttggtcaagg ggttgagttt gactacgcaa ccgttcactc tgttaaggct
    22261 atccaggcag ctggttatga agctatcatc atgaactcaa acccagagac cgtttcaaca
    22321 gacttctctg tatcagataa gctttacttt gagccattga cattcgaaga tgttatgaac
    22381 gtcattgact tggaacaacc aaagggagtt atcgttcagt tcggtggtca aacagccatc
    22441 aaccttgcgg agccattggc aaaagcaggt gtgaccatcc ttggtacaca ggttgctgac
    22501 ctagatcgtg ccgaagaccg tgacctcttc gagcaagctc tcaaagaatt ggatattcca
    22561 cagccaccag gacaaacagc taccaatgaa gaagaagcag ctcttgcagc tcgcaagatt
    22621 ggcttcccag ttcttgtccg cccatcttat gtacttggtg gacgtgccat ggaaatcgtt
    22681 gaaaacgaag aagaccttcg ttcttacatg cgaactgctg ttaaggctag tccagaccac
    22741 ccagttcttg tcgactctta tatcgttggg caagagtgcg aagttgatgc catttcagat
    22801 ggtaaaaatg tactcattcc tggtatcatg gagcatatcg aacgtgctgg tgtccactca
    22861 ggtgactcaa tggctgttta cccaccacaa accttgtcgc aaaaggttca ggagaccatc
    22921 gcagactaca ccaaacgctt agcaatcggt cttcactgcc ttggaatgat gaacatccag
    22981 tttgttatca aggatgaaaa agtctacgtt attgaggtca atccacgtgc cagccgtact
    23041 gttccattcc tatctaaggt aaccaatatt cctatggctc aagtagcgac caaactcatt
    23101 cttggtcaaa gtttatcaga acttggctac caaaatggac tttaccctga aagcacccgt
    23161 gttcatatca aggcacctgt cttctccttt accaaactag ctaaggtaga cagcttgctc
    23221 ggtcctgaaa tgaagtcaac aggtgaagtt atgggttctg atgctacttt ggaaaaagct
    23281 ctctataaag cctttgaagc ttcttatcta cacttgccaa cttttggtaa tgtcgtcttt
    23341 accatcgctg atgatgccaa agaagaagcc ttgaacttgg ctcgtcgttt ccaaaacatt
    23401 ggttatggaa tccttgcgac agaagggaca gcagccttct ttgctagcca tggcttgcaa
    23461 gcccaacctg ttggtaagat tggtgatgac gataaggata tcccaagttt tgtacgcaaa
    23521 ggaagaattc aagctatcat taacacagta ggaacaaaac gaactgctga cgaagatggt
    23581 gagcaaattc gtcgttcagc cattgaacac ggggtgcccc tcttcacagc gctagataca
    23641 gctaatgcca tgcttaaggt acttgaaagt cgtagctttg ttacagaagc gatttaaata
    23701 gaaaaataag atatagcaga ctgaatttag aacagtacac aggaatacta aaatatttct
    23761 agaaattaat ttgaattttc taattgattt gttcgcatct tatttcaatc tactatagaa
    23821 aaaagtcttt aaaattataa aacgcatcat atcaaggttt ttcaaaaacc ttgatatgat
    23881 gcgttttatt gtgggaatat gtatttcatt ttctactaaa attatgtttt tgaataacct
    23941 ctatcttagt agtttgtata atccccctca atcagttttt gcgataagct ttaatgctat
    24001 gactatacca ctcttgcatt tcttttgatg gtggtgtcat ataatcgcca tacatctggg
    24061 ttaaaaattg gtcatatttt ttgggaacag gcaacatacg gccctcaaac tcagttaaaa
    24121 tcagttcttt aaaggtatca actgggaaga tttctttcat cccttcctta ccgatcccaa
    24181 ctcctccttc atattgagga atgttggtta cagcattttt gactagttga tcaattttct
    24241 tgtaaaagta gcgaggattg acaaatcgga gagcgtacca gctacataat ctaagaaaat
    24301 cttttagttt gctatcaccg tgaactgctc gtgatttttt gatgtaagct agttgacgaa
    24361 gggccacata cttatagctc ttgtcgacaa tgctcaagtc tgtaaattga tcaattggga
    24421 agacatcgat gaaaaggctg gtatcatgac gcttgtactt aacatggtct tctataacag
    24481 tagaagtatc caaaatcgat gcgaaattat ggaagtacca agaagatgta tcgtaggaaa
    24541 gaaccttgta gcgagggtga ttttcttctt caataatctt cagtaaacgc tcataatcct
    24601 cacgataaag ggaaatatca atatcatcat cccaaggaat catacctttg tggcggatgg
    24661 ctccaagcat ggttccataa ctgagaaaat aaggaatatc atgtttctta caagtctcat
    24721 caatatagtc cagcagggct agttgaattt ctttaatttc ttttttttct aaatattgca
    24781 tcctaatcct ccaatttata agcgtgaaat tcatgactgt agaagcgttt ttcttctggt
    24841 ggtagggtca tataatctcc ataaaattgt gtcaaaatag tatcaaattt ttcaggtgca
    24901 ggaaggctta aattctcaaa gggtaaatcg attgttttat caaaggtagc acttgggaag
    24961 acttcctttt ccttaaattt tgaaggaata aaagccatat actgcccatt ttcacgacta
    25021 tatttttgaa tttctttctc gattttattt gcaaaataac gaggagaaac cagtcgaagg
    25081 agcaaccaaa aggctgttcg tatccaatct tttaaaaggc tatccttata gacaatattt
    25141 ttatgtttac tgaaagacag cagtttgaag ctttctagtt tataacaagt atcaatgacc
    25201 ttaggatcat caaagcgatc catagggaaa atatcgataa agataccaga ctcataggtt
    25261 tttgtatttc gagtatcaat aattttagtc gtactgtcgg ttatcttgat aaagttgtta
    25321 aagtagttct tatcagtttc taaggatagg agcttatact tgcttttttc cttttgaaaa
    25381 atgttaataa atcgttggta gtcttctcta ggcatggata aatcaatatc gtcgtcccaa
    25441 gggataaagc cctcatgtcg aaccgcccca atcagagtac cgtagttaat aatatagttg
    25501 atattgtgct ttttacagag agtatcaata taattcaaaa tttctaattc aatttgtttg
    25561 gcatcttcaa cggttagttg tttcatttta aactcctaag attttttaaa tttatttttt
    25621 aaggctagga catggtttaa aaattcatag aaaatgctat cttttgtgaa gacaagtaga
    25681 ctaatataag agatagctga tagcaagaca atcaaaccag tattaatcaa aaatggcaaa
    25741 ttaatgacca tatccacagg atacacgaaa ttaatcagga aataaattgc tacaaaggaa
    25801 agtgaaaaga gagagtatcg aacagtatag ctaaagatat gtcccaagtg gatgagttgt
    25861 tttctatgga tgaaaatgat atagaaaaca agtagagaag cctctgataa catagttgtc
    25921 agtaagtagt attcgggagc cacgatatgg ttgaaaaaga ggagactatt caagcccaaa
    25981 ttgagtagcc cagcaaagac tgtatagact gtgatacgtt tttcatagcc attggtaaag
    26041 agaatttggg aaccaagaat ggtatctaag gccaggataa tcgtacgaaa agcgaagaga
    26101 gaggtcaaga tgtcgcctcc gatatatttt tcactaccgt aaagtaggat ggcatttggt
    26161 cctaaaacca tgagtccaaa actcagtgga atgataaaga agttaaagat tcgactacct
    26221 ctattaacca gagaaacata ggcttctttg tctcctttcc ccagatagta actgagacga
    26281 ggcacactca ctccaattgc acctgttaca accccagcta taacggtcac aattcgctga
    26341 gctatggtat agtaactaac gttgacatca atccctgttt taacgaggaa gaggcgatct
    26401 aaaaaagtga agagcatatt ggcattggca aagactaaca tggctgtcag agggagaaag
    26461 agtggtttaa aatcacttag gtgaatctta acaagtttga tgtctctttt aatccaaaaa
    26521 taactaatca ggtagttaat cagcgtcgat aaactcatca caagtgtata gacaacaata
    26581 tcgtgttcat ttttaacaaa taagaaaata gagaccagca tcaggatacg gatgaaggca
    26641 gttttgtaaa agagaaaact gtaattttcc agagcttcat tgacccattc gattgaaaaa
    26701 atctgggcaa tgagttgaat ccccataaca aggtagacct ttttgacgat tggattatca
    26761 gtaaagaaga gaggataggc taggatatag acagcagtgg tcaaaatcgt acaagcgatg
    26821 cacaaataaa aaagactaga aaaggttctg ttaagatctt ttttgttatc cttgacatta
    26881 ctgatagccc ttaaaccgta gttatagaca ccataagttg caaagggcaa gaaaaatgac
    26941 aaaatagtgt cgactgagtt gaagtaacca tagtcagttc ggtccaagac acgcgcgaca
    27001 taggttccag ttaggatggg aaaaataata ttcaagacac gaattcccat gtaagataga
    27061 gcatttaatt ttatactttt cattcaattt acctcgtttt tcattatatc ataaagttag
    27121 ctaataagaa atgaagggca gtaagtcaag taatcacttt gaagtttcaa atcttaagtt
    27181 ttaagttttc tttaaggaaa gtatattatt ctgaaggact ctaaaatttc gcagccattt
    27241 attagtaatt gctacagaat tcctagtcat tactagaaat ggactagttt ctttgaataa
    27301 tagaactgca taattctcct attctagaag gggaggacca gtatttcttt tatgatagga
    27361 ctagattgtg gtataataga gagaataagt ttttttagta agacaaagga gaaaatagat
    27421 gatttatgca ggaattcttg ccggtggaac tggcacacgc atggggatca gtaacttgcc
    27481 aaaacaattt ttagagctag gtgatcgacc tattttgatt catacaattg aaaaatttgt
    27541 cttggagcca agtattgaaa aaattgtagt tggtgttcat ggagactggg tttctcatgc
    27601 agaagatctt gtagataaat atcttcctct ttataaggaa cgtatcatca ttacaaaggg
    27661 tggtgctgac cgcaatacaa gtattaagaa aatcattgaa gccattgatg cttatcgtcc
    27721 gcttactcca gaggatatcg ttgttaccca cgattctgtt cgtccattta ttacacttcg
    27781 catgattcag gacagtatcc aacttgccca aaatcatgac gcagtggaca cagtggtaga
    27841 agcggttgat actatcgttg aaagtaccaa tggtcaattt attacagata ttccaaatcg
    27901 tgctcacctt tatcaaggac aaacacctca aacattccgt tgcaaggact tcatggacct
    27961 ttatggatct ctttctgatg aagagaagga aatcttgaca gatgcatgta aaatctttgt
    28021 gatcaaagga aaagatgtgg ccttggccaa aggtgaatac tcaaatctga agattacaac
    28081 cgtaacagat ttgaagattg caaaaagtat gattgagaaa gactagtaaa atgattaatc
    28141 aaatttatca actaactaag cctaagttta tcaatgtcaa atatcaggaa gaggctattg
    28201 accaagagaa tcatatcctt atccgtccca actacatggc tgtctgtcat gcggatcagc
    28261 gttactatca gggaaaacgt gatcccaaga ttttgaataa aaagcttcca atggcaatga
    28321 ttcacgagtc atgtggaacc gtcatttctg acccgaccgg aacctacgag gttggtcaaa
    28381 aagttgtcat gattcccaat cagtctccta tgcagagtga tgaagaattc tatgaaaact
    28441 acatgacagg gacccatttc ttgtctagtg gatttgatgg ctttatgaga gagtttgttt
    28501 ctctccctaa agatcgtgtg gtggcttatg atgctattga agatacggtt gcagccatta
    28561 cagagtttgt cagtgtgggc atgcacgcta tgaatcgtct attgactctt gctcatagca
    28621 agcgggagcg gatcgccgtt attggagatg gaagtttagc ttttgtggtt gccaatatta
    28681 tcaactatac tttgccagaa gcagagattg tggttattgg tcgtcattgg gaaaagttgg
    28741 aactcttctc atttgccaaa gaatgctata ttacggataa tattcctgaa gagttggcct
    28801 ttgaccatgc ttttgaatgt tgtggtggtg atggtactgg accagctatt aatgacttga
    28861 ttcgctacat tcgtcctcag ggaacgattc tcatgatggg agttagcgaa tataaagtca
    28921 atctcaatac tcgcgatgcc ttagaaaagg gcttgatttt ggttgggtca tctcgttctg
    28981 gtcgcattga ttttaaaaat gctatccaaa tgatggaagt caagaaattt gccaatcgtc
    29041 ttaaaaatat cctttatcta gaagaacctg taagagaaat taaagatatt catcgtgtct
    29101 ttgcaaccga tttaaacaca gcctttaaaa cagtgtttaa gtgggaagta taagtactgg
    29161 aggttaattg tggagaaaat cattaaagaa aaaatttctt ccttacttag tcaagaagag
    29221 gaagtcctca gtgttgaaca actgggtgga atgaccaatc aaaactattt ggccaaaaca
    29281 acaaataagc aatacattgt taaattcttt ggtaaaggga cagaaaagct tatcaatcga
    29341 caagatgaaa agtacaatct tgaactacta aaggatttag gcttagatgt aaaaaattat
    29401 ctttttgata ttgaagctgg tatcaaagta aatgagtata tcgaatctgc gattacgctt
    29461 gattcaacgt caatcaagac caagttcgac aaaattgctc caatattaca aactattcat
    29521 acgtctgcta aggaattaag aggagaattt gctccttttg aagaaatcaa aaaatacgaa
    29581 tccttgattg aagaacaaat tccttatgcc aactatgaat ctgttagaaa tgcagtcttc
    29641 tccttagaga aaagactggc tgacttaggt gttgacagaa aatcttgtca tatcgatttg
    29701 gtgcctgaaa actttatcga atcacctcaa ggacgacttt atttgattga ctgggaatat
    29761 tcatcaatga atgatccaat gtgggatttg gctgccctct ttttagagtc tgaattcact
    29821 tcccaagagg aagaaacttt cttatctcac tatgagagtg accaaacacc ggtttctcat
    29881 gaaaagattg ctatttataa aattttacaa gatactattt ggagtctatg gactgtctat
    29941 aaggaagagc aaggtgaaga ttttggtgac tatggtgtga atcgttacca aagagctgtt
    30001 aaaggtttgg cttcttatgg aggttcagat gaaaagtaaa aacggagttc cttttggcct
    30061 tctctcaggt attttctggg gcttgggtct aacggttagt gcttatatct tttcgatttt
    30121 tacagatttg tcaccctttg tggtggctgc agctcatgat tttttgagca tctttatctt
    30181 actagctttt ctcttggtaa aagaagggaa agttcgcctc tcaattttct taaatattcg
    30241 caatgtcagt gttatcatcg gagccttgct agcaggccct atcggtatgc aggccaatct
    30301 ttatgcagtt aagtatatcg gaagttcttt agcttcatct gtatcggcta tttaccctgc
    30361 gatttcagtt ctattggctt tcttcttttt gaagcacaag atttcgaaaa atactgtatt
    30421 tgggattgtc ttgattattg gagggattat tgcccagacc tataaagttg aacaggttaa
    30481 ttctttctac attgggattc tttgtgcttt ggtttgtgct attgcatggg gaagtgagag
    30541 tgttcttagc tcttttgcca tggaaagtga attgagtgaa atcgaagccc tcttaatccg
    30601 tcaagtaact tcgttcttgt cctatcttgt gattgtgctc ttctctcatc agtcatttac
    30661 tgcagtagcc aatggacaat tgctaggtct catgattgtt tttgcagcct ttgatatgat
    30721 ttcctacttg gcttattata tcgctatcaa tcgcttgcaa ccagccaagg ctacaggctt
    30781 gaacgtgagc tatgtagtat ggacggtctt gtttgcagtt gttttcttgg gtgcaccgct
    30841 agatatgctg accattatga cgtcacttgt cgtcattgct ggagtttata ttattattaa
    30901 agaataaagg agattcgtgt gaaagccatc atcttagcag cgggattggg aactcgcttg
    30961 cgtcctatga ctgaaaatac ccctaaagcc ttggttcagg ttaatcaaaa acctttgatt
    31021 gagtaccaaa ttgagtttct caaagaaaaa ggaatcaatg acatcatcat cattgttggt
    31081 tatcttaaag aacaattcga ttacttgaaa gagaaatacg gtgttcgtct cgttttcaat
    31141 gataaatacg ctgactacaa taacttttac tctctctatc ttgtaaaaga agaattagcc
    31201 aatagttatg ttatcgatgc cgataactat ctctttaaaa atatgttccg caatgatttg
    31261 acacgttcta cttattttag tgtctatcgt gaagattgta ccaacgaatg gttcttggtc
    31321 tatggagatg actacaaggt tcaaaacatt attgttgata gcaaggcagg tcgcatcctt
    31381 agtggtgtat ccttctggga tgctccaaca gcagaaaaaa ttgttagctt tatcgataag
    31441 gcttatgcaa gcggcgaatt tgttgatctc tattgggaca atatggttaa ggataacatc
    31501 aaagagctag atgtctatgt tgaagaatta gaaggcaata gcatttatga gattgatagt
    31561 gtccaagact atcataaatt agaagaaatt cttaaaaacg aaaattaaaa gcttccaaca
    31621 tctgacaaaa tagtcggatg tttttttgat tttttacgaa cttttacgaa tagatagatg
    31681 agtagaaaaa gaaatggagt tatttatgaa aatcacaaac tatgaaatct ataagttaaa
    31741 aaaatcaggt ttgaccaatc aacagatttt gaaagttcta gaatacggtg aaaatgttga
    31801 tcaggagctt ttgttgggtg atattgcaga tatatcaggt tgccgtaatc cagccgtttt
    31861 tatggaacgt tattttcaga tagacgatgc gcatttgtcg aaagagtttc aaaaatttcc
    31921 atctttctct attttagatg actgttatcc ttgggatttg agtgaaatat atgatgcgcc
    31981 tgtactttta ttttacaagg gaaatcttga cctcctgaaa ttcccgaagg tagcggtcgt
    32041 gggcagtcgt gcttgtagca aacagggagc taaatcagtt gaaaaagtca ttcaaggctt
    32101 ggaaaatgaa ctggttattg tcagtggtct ggccaagggc attgacacag cagctcatat
    32161 ggcagctctt cagaatggcg gaaaaaccat tgcagtgatt ggaacaggac tggatgtgtt
    32221 ttatcctaaa gccaataaac gcttgcaaga ctacatcggc aatgaccatc tggttctaag
    32281 tgaatatgga cctggcgaac aacctctgaa atttcatttt cctgcccgta atcgcatcat
    32341 tgctggactt tgtcgtggtg tgattgtagc agaggctaag atgcgttcag gtagtctcat
    32401 tacgtgtgag cgagcaatgg aagaaggacg cgatgtcttt gctattcctg gtagcatttt
    32461 agatggacta tcagacggtt gccatcattt gattcaagaa ggagcaaaat tggtcaccag
    32521 tgggcaagat gttcttgcgg aatttgaatt ttaaaaatga cctaagctag aattctaaga
    32581 aaaaatcaat tttaagagaa aatgaaccca acatttccat aataaaacgc atattagcaa
    32641 gtttttaaca cttgataata tgcgtttttt ctaagtggat tagtagagta gaggattttt
    32701 ctcatataat actcttcgaa aatctcttca aactacgtca gcttccatct gcaacctcaa
    32761 aacagtattt tgagctgact tcgtcagtct tatctacaac ctcaaagcag tgctttgagc
    32821 aacctgtggc tagcttccta gtttgcgctt tgattttcat tgagtataag ggaaagtata
    32881 gtgaattgaa ataagatgtg aacaactcta tcaggaaagt caaattaatt tatagaaata
    32941 ttttagcagc caaggtgcac tgttatagat tcaatacact ataatttagt gtaattgaga
    33001 aaggagaaat gattgtgatt gatgttggct aggttatgtt caatgattcc taccgtctca
    33061 aatcttgtca gtaaggaaaa ataaattctt caaaagtaga gattacaagg cttgtttaag
    33121 aaagaattca aagaccttga caaataaaaa taaaatggtt attataaaaa atggtctgaa
    33181 atagatgatg atacttttcg aaaatctttt tacgtcagct cagctttgcc ttgctgtgtt
    33241 ttgagcaagc tacggttagc ttccgagttt gattttcatt tactagaaat gaaactgatg
    33301 agagatatca gtagacattt gagtcaggat attatggaaa atgataaaaa gagctcgtga
    33361 gattggcata tcagactact aaagtattga gtttgttagg attttagcga ctagttagct
    33421 gggaaaggaa gatatttgtg acaaataata aactgtattc gttgatagaa tttagaaata
    33481 aaatatatga agaattagaa ctttccagaa gtgatttagc gattttacta tgtgccatgc
    33541 ttatcgcctc tatcggatta aatatggatt cgactcccgt gattattgga gccatgttaa
    33601 tctctccttt gatgacacct attctgggag tggggctctc tctagctata tttgatttta
    33661 aattgttaag aaaatctttt aaaatattag ctattcaaat tcttgccagt ttaatagctt
    33721 caacacttta tttttatctt tctcccattt cgtatgctag ttcggaaatt gttgctagaa
    33781 cctctccgac tatttgggat gttctcattg cttttgtagg agggatagca ggtattattg
    33841 gtgctaggaa aaaagagacc aataatattg ttcctggtgt tgctattgca accgccttga
    33901 tgcctcctct ttgtacagta ggttatgcta ttgcttctgc taatctaaaa tttatcatag
    33961 gctcctctta cctattcctc atcaattgta gctttattgt cattgcgact tatataggtg
    34021 ttaggttgat gatggttaag aaacattatt ttaaagataa tgaagaagac tctaaaatgc
    34081 gtaggatttt gcttctagtt gctgttttgc tgatgattcc gagtttcatc tctgcaacga
    34141 ctttagtgag agaaacgttg aaaaaagagt cccttaagaa atttatatca gagcagtttc
    34201 aggggcataa tattttgaaa aaaacctatt ctaaaaagac tcatacccta aagctaacca
    34261 tttcaggaaa ttatttgaca gaagaagaac tcgatatgat ttcaagtaag agaggtgact
    34321 atggtttaag tgatgtttct gttcaagttt cacaattgtc tgattcagaa caacttagta
    34381 aggaagaact ggtggagtat ttcttccagt atatcaagga taaggaagca aaagaaaagg
    34441 aaaaagctaa taagttttat acagagtctg aggagcaata atttcttgag aatagctggt
    34501 ttctctcgtg agtcttctat gtatatcaaa ggaagactga ggttttaagt ataaaacttt
    34561 tcttctatta tagtagctaa gtcttgacag ggttcaaaaa atggtttaca ctttataaag
    34621 tttattactt tgaaaaggtg tgatactgtg gctacggcaa caaaaaagaa aaaatcaaca
    34681 gttaaaaaaa atctagtcat cgtggagtcg cctgctaagg ccaagacgat tgaaaaatat
    34741 ctaggcagaa actacaaggt tttagccagt gtcgggcata tccgtgattt gaagaaatcc
    34801 agtatgtccg tcgatattga aaataattat gaaccgcaat atatcaatat ccgaggaaaa
    34861 ggccctctta tcaatgactt gaaaaaagaa gctaaaaaag ctaataaagt ttttctcgcg
    34921 agtgacccgg accgtgaagg agaagcgatt tcttggcatt tggcccatat tctcaacttg
    34981 gatgaaaatg atgccaaccg tgtggtcttc aatgaaatca ccaaggatgc agtcaaaaat
    35041 gcttttaaag aacctcgtaa gatcgatatg gacttggtcg atgcccaaca agctcgtcgg
    35101 atcttggatc gcttggtagg gtattcgatt tcgcctattt tgtggaagaa ggtcaagaag
    35161 ggcttgtcag caggtcgcgt tcagtccatt gcccttaaac tcatcattga ccgtgaaaat
    35221 gaaatcaatg ccttccagcc agaagaatac tggacagttg atgctgtctt taaaaaggga
    35281 accaaacaat ttcatgcttc cttctatgga gtagatggta aaaagatgaa actgaccagc
    35341 aatgacgaag tcaaggaagt cttgtctcgt ctgactagta aagacttttc agtagatcag
    35401 gtggataaga aagagcgcaa gcgcaatgct cctttaccct ataccacttc atctatgcag
    35461 atggatgctg ccaataaaat caatttccgt actcgaaaaa ccatgatggt tgcccaacag
    35521 ctctatgaag gaattaatat tggttctggt gttcaaggtt tgattaccta tatgcgtacc
    35581 gattcgactc gtatcagtcc tgtagcgcaa aatgaggcgg caagcttcat tacggatcgt
    35641 tttggtagca agtattctaa gcacggtagc aaggtcaaaa acgcatcagg tgctcaggat
    35701 gcccatgagg ctattcgtcc gtcaagtgtc tttaatacac cagaaagcat cgctaagtat
    35761 ctggacaagg atcagctcaa gctatatacc cttatctgga atcgttttgt ggctagccag
    35821 atgacagcgg ccgtttttga taccatggct gttaaattgt ctcaaaatgg agttcaattt
    35881 gctgccaatg gtagtcaggt taagtttgat ggttatcttg ccatttataa tgattctgac
    35941 aagaataaga tgttaccgga catggttgtt ggagatgtgg tcaaacaggt caatagcaaa
    36001 ccagagcaac atttcaccca accgcctgcc cgttattctg aagcaacact gattaaaacc
    36061 ttagaggaaa atggggttgg acgtccatca acctatgcgc caaccattga aaccattcag
    36121 aaacgttatt atgttcgcct ggcagccaaa cgttttgaac cgacagagtt gggagaaatt
    36181 gtcaataagc tcatcgttga atatttccca gatatcgtaa acgtgacctt cacagctgaa
    36241 atggaaggta aactggatga tgtcgaagtt ggaaaagagc agtggcgacg ggtcattgat
    36301 gctttttaca aaccattctc taaagaagtt gccaaggctg aagaagaaat ggaaaaaatc
    36361 cagattaagg atgaaccagc tggatttgac tgtgaagtgt gtggcagtcc aatggtcatt
    36421 aaacttggtc gttttggtaa attctacgct tgtagcaatt tcccagattg ccgtcatacc
    36481 caagcaatcg tgaaagagat tggtgttgag tgtccaagct gtcatcaggg acaaattatt
    36541 gagcgaaaaa ccaagcgtaa tcgcctattc tatggttgca atcgctatcc agaatgtgaa
    36601 tttacctctt gggacaagcc tgttggtcgt gactgtccaa aatgtggcaa cttcctcatg
    36661 gagaaaaaag tccgtggtgg tggcaagcag gttgtttgta gcaaaggcga ctacgaggaa
    36721 gaaaagatta aataagagga ggggcccgaa agtaaatttc aggctccttt tggttagaac
    36781 ttgacaaaat acatcatttt atgcgaaact agaagaagat tattttatac tcaatgagaa
    36841 tcaaagagca aattagaaag ctagtcgcag gttgctcaaa gcactacttt gaggttgaag
    36901 atggaagctg acctggtttg aagagatttt cgaagagtat taactaggag aagttatgcg
    36961 tattatctat ctaattattg gttttttatc gctgaccttg gctattgttg gggttgtttt
    37021 acccttgttg cctacaacac ctttcctttt gttgtctatt gcttgtttct ccagaagttc
    37081 caagcgattc gaagattggc tttatcatac caagctctat caagcatatg tagctgattt
    37141 tcgtgagacc aagtctattg cgcgtgaacg aaagaaaaaa atcatcgtct ctatctacgt
    37201 cttgatggga atttctattt attttgcacc tcttttacca gtcaaaatcg gtctgggtgc
    37261 tttgaccatc tttattactt attatctctt caaggtcatt ccagacaaag aatagttaaa
    37321 acagtagtta tttgccttga taaaattgaa agcatattca taacaatatg atataataaa
    37381 attgaagtaa tattcaagga gaatcaaatg atttacgaat tttgtgctga aaatgtgact
    37441 ttacttgaaa aagcgatgca ggctggagct cgtcggattg aactctgtga taatctagca
    37501 gttggtggga caacacccag ctatggagtg actaaggcag cggttgaact ggcagctaac
    37561 tacgatacaa ccatcatgac catgattcgg ccacgtggtg gtgactttgt ctataatgac
    37621 ctagaaattg ctatcatgct agaagacatt cgtttgactg ctcaggctgg aagtcaaggg
    37681 gttgtatttg gagctttaac tgctgataaa aagttggata agcctaatct ggaaaagtta
    37741 attgctgcat caaaaggaat ggaaattgtc tttcacatgg cctttgatga actaagtgat
    37801 gaagatcaac cggaagctat tgactggctc agtcaagccg gtgtcactcg tatcctaact
    37861 cgtgctggtg tgtctggcga ctccttagaa aaacgttttg ttcactatca cagaattttg
    37921 gagtacgcta aaggtaaaat tgaaattcta ccaggtgggg ggattgacct tgaaaaccgt
    37981 caaaccttta tcgaccaggt gggggtaaca caattgcatg gtactaaggt tgttttttaa
    38041 aaaatagaaa ggaactgcta gctttgggta gcagttttca cttatgtttg aaatttttaa
    38101 atcctatcaa tttaatcaag aaaaggctca tgattatggt tttatagaaa atagcgaagt
    38161 ctggacatat agttgccaga ttttgcaagg tgactttgtc atgactgtgt ccatcactgc
    38221 tgataatgtg aactttcaag tctttgacca agagactggt gacctctatc ctcacgttta
    38281 tatggaaagc atgaggggaa gttttgtcgg aaatgtccgt gaggcttgtc tggagattct
    38341 ttaccagatt cggaaggctt gttttgatgt gcaagatttt atctgtcatc agactaagcg
    38401 tatcatgact caagttcagg aaaagtatgg aaaccagttg gagtatctgt gggaaaaatc
    38461 gcctgataca gctgtattgc gccatgaagg caatcaaaag tggtatgccg tcttgatgaa
    38521 aatctcttgg aataagctgg aaaagggcag agaaggacaa gtggaagcag tcaacctcaa
    38581 gcatgaccaa gtagctaatt tgctttcaca aaaggggatt tatccagcct tccatatgag
    38641 caagcgctac tggattagtg tgtcccttga tgatacttta tcagatgaag aagtactgga
    38701 attgatagaa aaaagttgga acttaacctc taaaaaatga aatattttaa taattttcat
    38761 gaactttcaa ttagctaaat attctttact gaagagattt ttagaaaata taggatttac
    38821 cacactagag gaatatggtg ccatcttcaa atacctgatt gagaatgtca agacggatcg
    38881 tcagatcatc tattcgcctc actgtcatga tgacctcgga atggcagtgg caaatagcct
    38941 tgctgctgtc aagaatggtg caggacgtgt tgaagggact atcaatggta ttagggagcg
    39001 agctgaaaat gctgctttgg aagaaattgc agtggctctc aatattcgcc aagattacta
    39061 ccaagtagaa accagtattg tcctaaatga gaccatcaat acgtcagaaa tggtttctcg
    39121 cttctctggt attccagttc ctaaaaacaa agccgtcgtt ggtggcaata ccttctccca
    39181 cgaatctggt attcaccaag atggagtcct taaaaatcct ctcacttatg agatcatcac
    39241 acctgaattg gttggtgtta agattctgct tggaaaatta tctggtcgcc atgcttttgt
    39301 tgagaaactg agagaattgg ccctagattt tacagaagag gatatcaaac cactctttgc
    39361 taagttcaag gcactggtcg ataagaagca agaaatcaca gatgcagata ttcgagcttt
    39421 ggtagctgga accatggttg aaaatccaga aggcttccac tttgatgatt tacaacttca
    39481 aactcatgca gataatgaca ttgaagcgct cgttagccta gccaatatgg atggtgagaa
    39541 agtcgaattt aatgcgacag ggcaaggttc cgttgaagca atctttaatg ctatcgataa
    39601 gttctttaac caatctgttc gtttggtgtc ctacactatc gatgcggtaa cagatggaat
    39661 cgatacccag gatcgggttt tggtcactgt tgaaaacaga gatacagaaa ccatctttaa
    39721 tgcagcaggg cttgattttg atgtgttgaa ggcttctgct attgtctata taaacgctaa
    39781 tacctttgtt caaaaagaga atgcaggtga gatgggacgc agtgtttctt accacgatat
    39841 gcctagtgtg taaaggagaa ggctatggca aagaaaatag tagctctagc aggagacgga
    39901 attggcccag aaatcatgga ggttggttta gaagttctgg aggctctagc tgaaaaaaca
    39961 ggttttgact atgagattga cagacgaccg ttcggaggtg cagatattga tgcagcatga
    40021 cctcccttac ctgatgaaac ccttaaggca agtagggaag cagatgctat cctactagta
    40081 gctatcggta gtcctcagta tgatggagca gtggttcgcc ctgaacaagg cctgatggct
    40141 ctccgtaagg aactcaatct ttacgctaat attcgtcctg taaaaatctt tgacagtctc
    40201 aagcatttgt cactactcaa actggaacga attgctggtg tagactttgt cgtggtgcgt
    40261 gaattgacag gcgggattta ctttggagat catattcttg aagagcgcaa tgcgcgtgat
    40321 atcaacgact atagctatga ggaagtggag cggattattc gcaaagcctt tgaaattgca
    40381 agaaatcgca gaaaaatcgt tactagtatc gataagcaaa atgttctagc gacctcaaaa
    40441 ctctggcgga aagtagctga ggaagtcgca caggatttcc cagatgtaac cttggaacat
    40501 cagctggtag actcagctgc tatgcttatg attaccaatc ctgctaagtt tgatgttatt
    40561 gtaacggaga atctttttgg agatatttta tctgatgaat caagcgtctt atctggtaca
    40621 cttggggtta tgccatcagc cagtcattct gaaaatggac caagtctcta tgaacctatt
    40681 cacagttcag cacctgatat tgcaggtcaa ggaattgcca atcctatttc catgatttta
    40741 tcagtttcca tgatgttgag agatagtttc ggacgttatg aggatgcaga gcgtatcaaa
    40801 cgtgctgttg agacaagtct ggcggcagga attttaacga gagatatagg aggtcaggct
    40861 tcaacaaagg aaatgacgga agctattatt gcaaggttat gaagttagac gaaaaaatta
    40921 ctctagtcct tttgatttgg aatgtcatca ttttcttgat ttatggtatt gacaaatcta
    40981 aggcaaggag aagagtttgg cgcatccctg agaaaatctt acttatttta gcctttactt
    41041 ttggtggttt tggtgcctgg ctagcaggaa tcatctttca ccacaagact cgaaaatggt
    41101 actttaaaat agtttggttt cttgggatgg tgaccacact agtagcctta tattttattt
    41161 ggaggtaatg gatggcaggg tcttcgaggg aatacgctgc ttgggctcta gcggactatg
    41221 gttttaaggt cgtgattgca ggatctttcg gtgacattca ttacaataat gaactcaata
    41281 atggcatgtt gccaatcgtt cagcctagag aggttagaga gaaactagcc cagctaaaac
    41341 caaccgacca ggtaactgtg gacttggaac aacaaaaaat catctcacca gttgaagaat
    41401 tcaccttcga gatagatagc gagtggaaac ataaactcct aaatagtttg gatgatatcg
    41461 gtattacctt gcagtatgaa gagttgattg ctgcttatga aaaacaacga ccagcctact
    41521 ggcaggatta gaaaaaatag aaaaggagat atagtaaact gaaataagat gtaaacaaat
    41581 gaattggagc ttaacatcca tttccagcaa ttttttagaa actacagtgg actattctgg
    41641 attcaacaca ttataaaatt atgacaaaac acattcacaa gaaggctacg acattttaaa
    41701 aggtgagggc ggatgtatcg tttgccctac taaagttggt tacattatca tgaccagtga
    41761 caaggcagga cttgagcgta agttcgcagc caaagaacgt aagcgtaaca aaccaggtgt
    41821 tgttctctgc ggtagcatgg atgaactttg cgctttagcg caactcaacc cagaaattga
    41881 agcattctac taaaaacatt gggatgaaga tattcttctt ggttgtatcc ttccttggaa
    41941 accagaagcc tttgaaaaac tcaaagcata cggggatggc cgtgaagaac ttatgactga
    42001 tgtacgtggt actagctgtt ttgttatcaa gtttggaaaa gcaggtgaac aattggctgc
    42061 caagctttgg gaagaaggta aaatggtcta cgcctcatct gcttcaatga caaaacgatt
    42121 gaaactcgct atgagcaagg tgtaatggtg tctatggtcg ataaggacgg caaactcatc
    42181 ccagaacaag gaggagcacg ttcaacttca ccagctccag ttgtgatccg taaagggctt
    42241 gacattgata tagtaaaatg aagtaagagc aggacaaatt aatcaggaca gtcaaatcga
    42301 tttctaacaa tgttttagaa gtagaggtgt actattctag tttcaatcca ctataaaatc
    42361 atgatgcacc tgtcagatac ttttaactca tgggactacc gtcaggttga gtattattag
    42421 gatagagaag aagtctagtg ttaaggacat tacagctcat aatactaggc ttttttatag
    42481 aaattctttt ctttttctat aggatatggt attctatgta gaaaatatat gttaataagt
    42541 aatgccaata tttaaacatc attagtaaaa ggagttagat tgatgaataa aagaaaagtt
    42601 agtttagaag atttttataa atggtatagt ctaaataaag aagagttatt aaataaggca
    42661 actgttggtg aaaagtttaa tgataaatta aaagaagagt ttctccagga atggcctttg
    42721 gataggattt taacaatgtc aatcgatgaa tatgtaatag gaaagggaca gcaaaataag
    42781 tctttatgct acgctcttga gaagggaaaa tacaaaaatc tatttcttgg aatttctggt
    42841 ggctcagctt caaaatttgg tatttattgg aataaaaaaa caaacaaata taaagatcaa
    42901 gctaataatg agatttcaga gttggatcag cgattttcaa aattaaaatc agatttgtat
    42961 gaaattatca aagaaggtat tcgttttaac tttgaaaatc ctatttttga tatgaaaaga
    43021 tcaacaaatg aatttattgg tcgttctgct atggtgacaa aattactttg tatctatact
    43081 gagggagatc ctttctttgg tgtaaatatt aatagtcaga aagaattttg gaaccacttt
    43141 gtttctcaga caaatcaagg tggaccttat ctgcaaaatc ataaaataat tgaactgatg
    43201 tccaaaactt atcctgagtt ggagccatcg aaattaggaa ctatgctttt tgagtattct
    43261 aagcttttta tggaaaataa ggaagacaat agtacaatgg attcatcaaa caattttcgt
    43321 catcaattaa ctcaatctct attaaagtct ccaaacctta tccttcgtgg tgctcctggc
    43381 acaggaaaga cttatcttgc taaagaaatt gccaaagaat taacggatgg caacgaagat
    43441 caaatcggat ttgtacaatt tcacccatca tatgattata cggattttgt agaaggttta
    43501 agaccagtat caaatgggga tggagctatt gagtttaggc tacaggacgg tatttttaaa
    43561 gatttttgtc agaaagcaaa agaaacccaa ttgattggag gacaagataa ttttgatgag
    43621 gcttgggatt cttacttaga atatataaat gttgctgaag aaaaagaata tataacaaaa
    43681 acatcttact tatctgttaa tagtagacaa aatttgtcag taaattatga tagtggtgtt
    43741 ccaggatggt cactacctag caaatatgtt tacgagttgt ataaagataa aaattataat
    43801 aagcaagaat actacaaaag tggtggaaaa actgtcctag aaacattgag aaagagattt
    43861 ggtttgaaag actatgtttc cccaacagaa attgatactg ataagaaatt cgttttcatc
    43921 atcgatgaaa tcaatcgtgg ggagatttct aagatttttg gcgaactctt tttctctatc
    43981 gaccctggct atcgtggtga aaaaggaagt gtttctaccc aatatgcaaa tctacacgaa
    44041 actgatgaaa agttctatat ccccgaaaat gtttacatca tcggaactat gaatgatatt
    44101 gatcgttcag tggatacctt tgattttgct atgcgtcgtc gttttcgttt tgttgaagtt
    44161 actgccgagg gtcaagttgg catgttggat aaagagctga atatccatgc agaagaagca
    44221 aaaattcgtc taagaaactt gaacgctgct atcgaaaatg ttcaggaatt aaacagtcat
    44281 tatcatattg gaccaagtta ttttcttaag ttgaaggatg tagattttga ctatgaatta
    44341 ctctggtccg attatattaa gcctctccta gaagactact tgcgaggttc ttatgatgag
    44401 gttgaaactt tggaaacttt gaaaaaagca tttgaactga caaataatga gcaaaaagat
    44461 caggcagtag ctgatgacaa tgaaagcgat gaaaacgatg atgcggatta ctgataatca
    44521 acacaagatt attaaagaaa aatttgttga agaatatcct aaactaagca atcttctttt
    44581 agacagaacc ttggaaagtc tatcccaaga tgaacgtatt ttcatttttc caaatgattt
    44641 gactcatact ccagatttgg ataaaaaaca aaagattttg gaaacgatca atcaggaaat
    44701 caagacagga aatgtgattg gttttcttgg atatggtcag gaaagattaa cgatttcctc
    44761 acgattttct gatgagagta atgaccattt tttgcattat ctcttaaaca aggttcttca
    44821 tatcaatctc actagtttag atgttgcttt gtctcgtgaa gagaggcttt atcaactttt
    44881 gatgtatctc ttccccaagt atctacaagc tgctattcga aaaggtcttt ataaggaata
    44941 tcatcgattt tctcataacg acagtcatgt taagggagtg attgatgtaa gaaaccatct
    45001 caagaaaaat cttcctttca cgggaaatat tgcctacaca acgagagagt tcacctatga
    45061 taatcccctc atgcagttgg tccgtcacac tattgaatac attaagaatc agaaaagcat
    45121 tggtcaaggg gtactagata atctctcaac tagtcgtgaa aacgtatctg aaatcgtgcg
    45181 tgtaacgccc tcttataaac tagctgatcg tgctaagatt attcggggaa atcaatctaa
    45241 acctatacgt catgcatact ttcacgagta cagaaactta caagaacttt gtctgatgat
    45301 cctaaaccaa gaaaagcacg gtttagggta tcaagatcaa aaaatctatg gtattctctt
    45361 tgatgttgcc tggctttggg aagagtatgt ttacaccttg ttgccaaaag gttttgtaca
    45421 tcccagaaat aaggataaga cggatggaat ttcagtattt tctgttggga aacgaaaagt
    45481 atatccagat ttttatgaca gagaacgaaa gattgttcta gatgcaaaat ataaaaaact
    45541 ggaattgact gaaaaaggaa tcaatcgtga ggacttattc cagctgattt cctattctta
    45601 tattttaaaa gctgagaagg ctggacttgt ttttccgagc aaggacaagg ttattgataa
    45661 tgagatggga aacctagcag gttatggagc tttgttgaag aaatggtcta tccaaattcc
    45721 tcagaagtct tcatcttata gtgcattttg taaaatgatg gaaaattcag attatagtgc
    45781 attttgtaaa atgatggaaa attcagaaga aaattttaaa gcgattattg atgaagaagt
    45841 ggggagaaaa taatttcccc tctttctttt atttttaaca caagtaaaac ccgaacaata
    45901 tatttcaatt cataaaataa tttgacaaaa actgtacttt ggtttataat aaattaagga
    45961 aacgtcggaa aagacgtagt gatgcgagag cataggtagg tcattacaaa agaaacgaga
    46021 catcgatatg ttaaatgaat ttccaatttt tgattacgaa gatattcaat tgattccaaa
    46081 taaatgtgtc attaaaagcc gtgcagaagc ggatacaagt gtcactttag gaaatcacac
    46141 ctttaaacta cctgttgtgc cagcgaatat gcagacgatt ttggatgaaa atgtagcaga
    46201 gcaactggct aaaggtggtt acttctacat tatgcaccgt tttgatgagg caggacgcat
    46261 tccttttatt aaacaaatgc acgatcaagg gctcattgct tccatctctg tcggtgttaa
    46321 ggactatgag tatgattttg ttagccagct caagactgat gctcctgagt atatcactat
    46381 tgatattgct catggtcatg cggatagcgt gatttctatg attcaacata tcaagaaaga
    46441 attgccagat acctttgtca ttgctggaaa tgtgggaaca ccagaagctg tgcgtgaatt
    46501 ggaaaatgct ggtgcggatg ctactaaggt cggaatcggt cccggtaagg tttgtatcac
    46561 caaggttaag actggttttg gtacaggtgg ttggcagttg gctgctctac gctggtgtgc
    46621 caaggctgcg cgtaaaccga ttatcgctga tggaggaatt cgtactcacg gtgatattgc
    46681 taagtctatc cgcttcggtg ctagcatgat catgattggt tccctctttg caggacacat
    46741 tgaaagtcca gggaaaacga ttgaagtcga tggtgaacag ttcaaagaat attatggttc
    46801 agcctcacaa tatcaaaaag gtgcttacaa aaatgtggaa ggcaaacgta tcttgcttcc
    46861 tgctaaaggt catctgcaag acactttaac tgagatggaa caagaccttc aaagtgctat
    46921 ttcttatgca ggtggacgtc aggttgctga ccttaaacac gttgattatg tgatcgtgaa
    46981 aaactccatc tggaatgggg atgcttccca ctaagacggg gtctttgacc aaaaaacttg
    47041 ttattagagc aaatttctgt tataataaaa caagtttcca cccttagtgt aatggatatc
    47101 acgtaagatt ccggttcttg agatgggggt tcgattccct cagggtggat gtaaacatcc
    47161 taaaaagcct ttaatagggc ttttttcttt atcctgaccc aaatttgccg ctaaaactga
    47221 gaatctctgt ctaaagaatt cccaaatgct ttccagtccc gttttagagt gactcagggg
    47281 gctttttttg atataataaa aaggactgtt atcagttaga aagaggttgg tatgaaagaa
    47341 ttacaaactg tactaaagaa tcattttgca atcgaatttg cagacaaaaa tttactggaa
    47401 actgccttta ctcatacgag ttatgccaat gagcaccgcc tcttaaaaat ttcacacaat
    47461 gaacgcttgg aatttttagg agacgctgtt ctacagttat tgatttcaga atatctatat
    47521 aaaaaatatc ctaaaaagcc tgaaggtgac ctatcaaaac tccgtgctat gattgtccgt
    47581 gaggagagtt tagctggttt tgcgcgtgat tgccagtttg accagtttat caagttgggt
    47641 aaaggggaag aaaaatcagg tggtcgcaat cgtgacacca ttcttggtga tgcctttgaa
    47701 gcctttcttg gtgcccttct tttggataag gatgtggcca aggtcaagga atttatctat
    47761 caagtcatga ttcctaaggt tgaagcaggc gaatttgaga tgattacaga ctataaaacc
    47821 catctccaag agttacttca ggtcaatggt gatgtggcta ttcgttatca ggtgatttct
    47881 gaaacagggc ctgctcacga taaggtcttt gatgtagaag ttcttgttga aggtaagagc
    47941 atcggtcaag gccaaggtcg ttctaagaaa ttagcagagc aggaagctgc caaaaatgcc
    48001 gttgagaagg ggctggattc atgtatttaa aggaaatcga aattcagggg ttcaagtctt
    48061 ttgctgataa gaccaaggtc gtttttgacc aaggtgtgac ggcagttgtt ggacccaatg
    48121 gatctggaaa gtccaatatt acagaaagtc tgcgttgggc tttgggggag tctagtgtca
    48181 agagtctccg tgggggcaag atgccggatg tcatctttgc tggaacagaa agtcgcaaac
    48241 cgctcaatta tgcttctgta gttgtgactc tggataatca tgacggattt atcaaggatg
    48301 caggtcaaga aatcagggtg gaacgccata tctatcgtag tggagatagc gaatacaaga
    48361 ttgacggcaa gaaagtccgt ctgcgtgata ttcatgacct tttcttggat acaggtttgg
    48421 gacgagattc cttctctatt atttcccaag ggaaggttga ggagattttt aattccaagt
    48481 ctgaggaacg acgagctatt tttgaagaag ctgctggagt tttaaaatac aagactcgca
    48541 gaaaagaaac cgagagtaaa ctgcagcaaa ctcaggataa tctggaccgc ttagaggaca
    48601 ttatctacga gttggataat caaatcaagc ctcttgagaa gcaagctgag aatgcccgta
    48661 aatttctaga cttagaaggt caacgcaagg ctatttactt ggatgtattg gttgctcaaa
    48721 tcaaggaaaa taaggcagaa ctagagtcga cagaagaaga gttggctcag gttcaagaac
    48781 tcttgatgag ttattaccaa aagcgtgaaa aattagaaga agaaaatcaa actcttaaaa
    48841 agcaacgcca agatttacag gctgaaatgg ccaaagacca aggcagtttg atggacttga
    48901 ctagtctgat tagtgattta gaaagaaaat tagccctatc gaaactggag tctgagcaag
    48961 tggccttgaa tcaacaggag gcacaagctc gtttggctgc tttggaggat aagagaaatt
    49021 cactcagcaa agaaaagtct gataaagaaa gctctttagc tctgttagag ggaaatctag
    49081 tccaaaataa tcaaaaactc aatcgtttag aagctgaatt gctggctttc tcagacgatc
    49141 ctgatcagat gattgagctc ttacgtgaac gctttgtagc tcttttacaa gaagaagcgg
    49201 atgtctcaaa ccagttgacc cgtattgaga atgagttgga aaatagtcgt cagctttctc
    49261 aaaaacaagc agatcaacta gaaaagctga aagagcaatt agctatagct aaagagaagg
    49321 ctagtcagca aaaggaagag cttgaaactg ccaaggagca ggttcagaaa ttattggctg
    49381 actaccaagc tattgccaag gagcaagagg agcagaaaac ttcctatcaa gctcaacaaa
    49441 gccaactctt tgaccgtctg gataatctca aaaacaagca ggccagagct caaagtttgg
    49501 aaaatatcct gagaaatcat agtaactttt atgcaggtgt taagagtgtt ctccaagaaa
    49561 aagatcgcct aggtgggatt attggtgcag tcagtgagca tctgaccttt gatatgcatt
    49621 atcaaactgc cctagaaatt gcgcttggag cgagtagcca acatatcatc gtagaagatg
    49681 aagagtcggc aaccaaggct attgacttcc ttaaacggaa cagagccggt cgtgcaacct
    49741 ttcttccttt gaccactatc aaggcgcgta cgatttctag tcagaaccaa gatgctatca
    49801 ctgtaagccc aggtttcctt gggatggcag atgagttggt gacttttgat actagactgg
    49861 aagccatttt caagaacttg ctagctacga cggctatctt tgatgccgta gaacatgcgc
    49921 gtgcagcagc tcgccaagtt cgttatcagg ttcgtatggt gacattggat gggacagaat
    49981 tacgcacggg tggttcctat gcgggtggtg ccaatcgcca aaataacagt attttcatca
    50041 agccagaact ggagcaatta caaaaagaaa ttgctgcaga tgaagcaagc ttgcgttcag
    50101 aagaagcggc tttgaagacc ttacaagacc agatggctac attgacagaa agattagaag
    50161 tcatcaaatc tcaaggagaa caggcacgta ttcaggagca aggcttgtcc ctcgcttatc
    50221 agcaaactag tcagcaagtt gaagaactgg aaactctttg gaaactccaa gaagaggaaa
    50281 tagatcgtct ttccgaggga gattggcaag cggataagga aaaatgccaa gatcgtcttg
    50341 ctgcaatcgc cagtgacaag caaaatctgg aagctgagat tgaagagatt aagtctaaca
    50401 aaaatgccat ccaagaacgc tatcaaaact tgcaggaaga gctagcgcaa gctcgtttgc
    50461 ttaagacaga actgcaaggg caaaaacgtt atgaagttgc tgatattgaa cgcttaggca
    50521 aggaattgga caatcttgat tttgaacaag aggaaatcca gcgccttctt caagaaaagg
    50581 ttgataatct tgagaaggtt gatacagaat tgctcagtca acaggcggaa gaagccaaaa
    50641 ctcagaaaac aaatctccaa caaggtttga ttcgcaagca gtttgagttg gatgatattg
    50701 aaggtcaact ggatgatatt gctagtcatt tggatcaggc tcgccaacag aatgaagagt
    50761 ggattcgcaa gcaaacacgt gctgaagcca agaaagaaaa ggtcagcgag cgcttgcgct
    50821 atttacaaag tcaattaaca gaccaatatc agattagcta tactgaagct ctagaaaagg
    50881 cgcatgaatt ggaaaacctc aatctggcag agcaagaggt gcaggattta gagaaagcta
    50941 ttcgctcact ggggcctgtc aatatagaag ctattgacca gtacgaagaa gttcacaatc
    51001 gtctggattt cctaaatagc caacgagatg atattttgtc agcgaaaaat ctgctccttg
    51061 agaccattac agagatgaat gatgaggtca aagatcgctt taaatcaacc tttgaggcca
    51121 ttcgtgaatc ctttaaagtg accttcaaac agatgtttgg aggaggtcag gcagacttaa
    51181 tcttgactga gggagacttg ttgacagctg gggttgagat ttctgttcaa cctccaggta
    51241 agaaaatcca gtcgcttaac ctcatgagtg gtggtgaaaa agccttatca gctcttgctt
    51301 tgcttttttc tatcattcga gttaagacta tcccatttgt catcttggat gaggtagagg
    51361 ccgcgctgga cgaagccaat gttaaacgtt ttggggatta cctcaatcga tttgacaagg
    51421 acagccagtt tatcgtcgta acccaccgta agggaaccat ggcagcggct gattctatct
    51481 atggagtgac catgcaagaa tcgggggtct caaaaattgt ttcggttaag ttaaaagatt
    51541 tagaaagtat tgaaggatga caattaaact agtagcaacg gatatggacg gaaccttcct
    51601 agatgggaat ggacgctttg atatggatcg tctcaagtct ctcttggctt cctacaagga
    51661 aaaagggatt tactttgcgg tggcttcggg tcggggattt ctgtctctgg aaaaattatt
    51721 tgctggtgtt cgtgatgaca ttattttcat cgcggaaaat ggcagtttgg tagagtatca
    51781 aggtcaggac ttgtatgaag cgactatgtc tcgtgacttt tatctggcaa cttttgaaaa
    51841 gctgaaaacg tcaccttatg tagatatcaa taaactgctc ttgacgggta agaagggttc
    51901 atatgttcta gatacggttg atgagaccta tttgaaagtg agtcagcatt ataatgaaaa
    51961 tatccaaaaa gtagcgagtt tggaagatat cacagatgac attttcaaat ttacaaccaa
    52021 cttcacagaa gaaacgctgg aagctggaga aacttgggta aacgataatg tccctggtgt
    52081 caaggctatg acaactggct ttgaatctat tgatattgtt ctggactatg tcgataaggg
    52141 agtggctatt gttgaattag ctaaaaaact tggtatcaca atggatcagg tcatggcttt
    52201 tggagacaat cttaatgact tacatatgat gcaggttgtg ggacatcctg tagctcctga
    52261 aaatgcacga cctgaaattt tagaattagc aaagactgtg attggtcacc ataaggacca
    52321 gtcggttata gcttatatgg agggcttata atggcagata taaaattaat cgcattggac
    52381 ttggatggta ccttgctgac tactgataaa aggctgacgg atcgcaccaa ggcaactttg
    52441 aaagctgcga gtgatcgtgg tatcaaggtc gtattgacaa ctggtcgtcc cttaaaagcc
    52501 atggacttct ttctccatga gttagggact gacggccatg aagatgagta taccattact
    52561 tttaatggtg gattagttca gaaaaataca ggagaaatcc ttgataaaac agtcttttca
    52621 tatgatgatg tggcacgttt gtatgaggaa acagagaaat tatcactgcc tcttgatgcc
    52681 atctcagaag gaacagttta tcaaatccaa tcggaccaag aaagtcttta tgccaaattc
    52741 aatccagctt tgacttttgt tccagttgac tttgaagacc tgtctagtca aatgacctac
    52801 aacaaatgcg tgactgcctt tgctcaagaa cccttggatg cagccattca gaagatttct
    52861 ccagaattgt ttgaccaata tgaaatcttt aaatcacgtg aaatgttgct agaatggtca
    52921 ccaaagaatg ttcataaagc aacaggtttg gcaaaactaa ttagccatct tggaattgat
    52981 caaagtcaag tgatggcctg tggtgacgag gccaatgacc tctctatgat tgaatgggca
    53041 gggctcggtg ttgccatgca aaacgctgtt cctgaagtaa aggcagccgc aaatgtagtg
    53101 acgccgatga ccaacgatga ggaagctgtc gcctgggcta tcgaagaata tgtgctaaag
    53161 gagaactaag atatgggatt atttgaccgt ctattcggaa aaaaagaaga acctaaaatc
    53221 gaagaagttg taaaagaagc tctggaaaat cttgatttgt ctgaagatgt tgatcctacc
    53281 ttcacagaag ttgaagaagt ttctcaagaa gaagctgtgc ttgaagaaag tcaggattca
    53341 gagccagctg taggggtttc tcaagaagaa atagaagaat taccagagga agagaagctt
    53401 gagcacgaag gaactataga agaaaataat tctgaagttc ttgaagcaga aaggcctcaa
    53461 acagaagaaa ctgttcagga aaaatatgac cgcagtctta agaaaactcg cacaggtttc
    53521 ggtgcccgct tgaatgcctt ctttgctaac ttccgctctg ttgacgaaga atttttcgag
    53581 gaactggaag aactgttgat tatgagtgat gttggtgtcc aagtcgcttc taacttaacg
    53641 gaggaactac gttacgaagc caagcttgaa aatgccaaga aacctgatgc acttcgtcgt
    53701 gtcatcattg agaaattggt tgagctttat gaaaaggatg gtagctacga tgaaagcatc
    53761 cacttccaag ataacttgac agttatgctc tttgttggtg tgaatggtgt tgggaaaaca
    53821 acttctatcg gaaaactagc ccaccgctac aaacgagctg gtaagaaggt catgctggtt
    53881 gcagcagata ccttccgtgc gggtgcagta gctcagctag ctgaatgggg ccgacgagta
    53941 gatgttccag tagtaactgg acctgaaaaa gctgatccag ccagcgtggt ctttgatggt
    54001 atggaacgtg ccgtggctga aggtatcgat attctcatga ttgatactgc tggtcgtctg
    54061 caaaataagg ataaccttat gactgagttg gaaaagattg gtcgtattat caaacgtgtt
    54121 gtgccagaag caccacatga aaccttcttg gcacttgatg catcaacagg tcaaaatgcc
    54181 ctagtacagg ccaaagaatt ttcgaaaatc acacctttaa cgggaattgt tttgactaag
    54241 attgatggaa ctgctcgagg aggtgtggtt ctagccattc gtgaagaact caatattcct
    54301 gtaaaattga ttggttttgg tgaaaaaatc gatgatattg gagagtttaa ctcagaaaac
    54361 ttcatgaaag gtctcttgga aggtttaatc taatcagaag caaaaatcct gcaaggcata
    54421 aacttgcagg aaattttttt attcgaaacg accatcttga cgataggcga tatctggttg
    54481 ccaagtccat ttggcaccga atttttcaag taggtcaaag ctggcttgag gtcccatgct
    54541 tccagcttta tagtcatgaa gtggggcacc attttcagcc cagagctctt caatacggtc
    54601 aatcaacttc catgatgcac caacttcatc ccagtggcta aagttagttg agttgttatt
    54661 taggacatca taaatcaatt tctcgtatgg ttctggagaa gcaccagttg cagtcgcatc
    54721 tgtacggtaa tcaagtgagt taggagccaa gttaaattct tctcctactt gcttcccatt
    54781 taggctaaga gagaagcctt ctgttggttg aatatagatg gtcaaaatat ttggagcaag
    54841 tggttctcca aagatagaat ccatttgttt aaagacgatg ttgacatgag ttcctttttc
    54901 agtcagtcgt ttacctgtac ggaaaaagaa aggaacacta cggaatcgat cgctgtctac
    54961 aaagaaggca ccagatgtaa aggtttcagt tgttgattct ggattcacat ttggctcgct
    55021 acgataagag atgtatttca tgccatcaat cttaccagag cggtattgcc cacggataaa
    55081 gtgttctttg agttcttcat cagttggatg atagaggttt ttaaagacct taatcttttc
    55141 agcacgaatc tcgtcttttg tgaagattgc tggtttgtcc atggcgagga gcgaaagaag
    55201 ttgtagagtg tggttttgga ccatgtcacg gagggcaccg gattggtcat agtagccacc
    55261 acgttcttct acacccaagc gctccgcaaa ggtaatttga acattgtcga taaaatcctt
    55321 gttccaaacg ttttcaaaaa tcaagtttgc aaagcgaact gcaaagatgc tttggatcat
    55381 ttccttacca agataatggt cgatacggaa aatttgttct tcgtcaaatg ttgctaggag
    55441 ttcgtcattc aacttgcttg cagttgcgta atctgtacca aatggttttt caacgatcaa
    55501 gcgctcaaaa cctttgccat cgacaatgtt ttcagatttg aggtgtttgg caatggttcc
    55561 aaagaactga ggtgccatag acaagaagaa gagcttattg tgttcagctt ggtatttttc
    55621 attaagctca gcttgtaatt gacgcaaagc aatataatgt tccgaatcat tgacatcatg
    55681 gctttgatag tagaagtggc tagcaaattc ttgggcttgc tcggtactat ctgccaaatc
    55741 aaggatggac tcgacaacta cagattcaaa atattcctta ctccaaggtc tacgggcagt
    55801 tccaataacg gcaaagtgct tggaaagatt gccggattga tatagtctaa aaagggaagg
    55861 gtagagcttg cgtttagcca ggtctccact cgcaccgaaa attgtaacaa taaccttaga
    55921 tgacatctag ctacctaatt tctattttta ttcctagtct tgctaggtat gaggaaacct
    55981 catttcataa acttaattct aacataattt tccgaaaaat caaaaattcc aatacgaggt
    56041 agaaaaactg caaggaaatc cttacagttt gagtttagac gtttaagacc ttatctaaga
    56101 actctttcag acgagggtgt tgtgggttat caaagatttg gtcaggtgtt ccgtcttcaa
    56161 ggaactcgcc atctgcagta aagataacgc ggttggcaac ctgacgagca aatcccatct
    56221 catgggttac gataatcatg gtcatgcctt gctcagccaa ttccttcata acgttaagta
    56281 cgtctccaac catctcaggg tcaagggcag aagttggttc atcgaagagc atgatgtctg
    56341 gattcattgc taggccacga gcgatggcca cacgttgttt ttgaccacct gataggttat
    56401 ctggattggc attagcttta tctgctagtc caaccttttc aagcaactcc attcccaatt
    56461 cctcagcttc ttccttagtc atcaacttgt gctcaatagg agcaaaggtg atgttgtcca
    56521 atacagacat atgagggaag aggttgaagt gttggaatac catgccgata ttttcacgga
    56581 cgtggtcaac attggttgtt ttttcagtta aatcatagcc gttcacagtg atgtgaccgc
    56641 tagtgacttc ttctaaaaga ttgaggctac ggaggaaagt tgacttacca gaacctgaag
    56701 gaccgatgat acaaacaaca tctccttcat agaacttagt cgtaattcct tttaggactt
    56761 cattttttcc atagtgcttg tgtaaatcat ttacatcaat ttttaatttt gccattaacg
    56821 aatcctcttt tctaagcgtt tcgctagtct agtcaaaagt gtgataatta caagatagaa
    56881 gatagcaagg attgcataca tcttgaaact ttggtagtta cgagcaatga taatcttacc
    56941 agtttggaag agttcaacca aaccgatagc agatacgata gttgtatctt taagagcgat
    57001 aacgaattgg ttgacaaagt ttggcaacat caatttagtt gcttgtggca agataatctt
    57061 acgcatggtt tttccataag agatacccaa gcttcggctg gcttccattt ggccaactgg
    57121 aacggcctga ataccaccac gaacgatttc agcgatataa gcagccgcat tgagtgagag
    57181 ggcaatggtt ccagctacaa agtcgttaat tgggctttgt tggcctgtga tagactcgat
    57241 gaagtttgga attccccaga agatgaaggc tgcaagaatc atcaatggaa taccacgaat
    57301 aacgtcaacg aaaatctcag agatgacgcg aagagatttg tatgggctaa cgctaaacat
    57361 accgaagata attccgatga caatggcaat agcaaatgag ataagagcta gagcaagagt
    57421 gataccaaga ccgctaagga gttgtttgta gttgttttga agcaagcccc agagcgttgt
    57481 ttcgtcaaca gtacttgttg aagcagttga agattcgcta gctaggtatt tgtcaagaat
    57541 cttttggaat tcaccgtttg ctttaaggtt tgcaagtccg ttgttgaaca tttcaatcag
    57601 ttctggattt gctccttttt taacggcaaa ggctgtttca ccgattggag ttccagagat
    57661 tggagttttc aatttttgac cttggctgat agaatatttg agaacaggtt catcatccat
    57721 aacggcatca atggcaccag tgtttaaact gtcatacatt gaagaaccat cagcaaaggt
    57781 tttgattttg taaccgtatt tgctttgatt ttctgttagg aaggtttgag aagcagttcc
    57841 gtttttaaca ccgactgtct ttccttttag atcttcataa gaagcaatat tgcttgattc
    57901 tttgacacca agaatggtat tagcagtgta gtatgattct gagaagtcaa aagttgcctt
    57961 acgagcatct gtgacagaca taccagcaat gataccatcg gcttgaccag cttggacagc
    58021 actgatagca gcatcaaaac cagggttggt gatttcaatt tcaaaacctt ggtctttagc
    58081 gattgcctta atcaattcca tatcaatacc agtgtattgg ttgcttgaat tttggaaaac
    58141 aaaaggtgca aaagaagaat cgctggcaat gatatattta gccttaacag gaatagcttt
    58201 taatcctgcg agagtagttg tagttggcac tgctgaagat gatgaagcag tccatttctt
    58261 gataatttta tcaagactac catctttttt catttcagcc aaggcttggt taaattcagt
    58321 aaccaggtgc tcgtatttac ttcctttttt cacaccgaaa gcaaaacttc ctacagcttc
    58381 accatccatt tcaatatgga ggtcttgacc ttggttaatg gcatattcga taacaggttt
    58441 gtcatccatc atggcatcga tggcaccagc actcaagctg ttgttcatta aatcaccagt
    58501 gtcaaatgtt ttaatagtaa agccgtattt atctttgatt gtttcaagga aacgttgagc
    58561 ggcagttccg tttttaacac caacggtttt gccagttaat tggtcgtact tgctaatttt
    58621 gtgtgacttt gtagtagcaa tgacaacttt tgtatcatag taagtatcag acatggtgaa
    58681 gactttttca cgttctttag tctttgtcat ccctgccatg atagcgtcgg cttgcccagc
    58741 ttgaaccgca ttgactgctg cgtcaaatcc aggataggac atctgaatgt tccagccttt
    58801 aatctcagcg actttgttaa taatgtcaac atcaattcct ttataagttt gatctgaatc
    58861 tttaaactca aaaggtgcat aggcggtatc agaaacaatc ttaatcgttt ctgctttggc
    58921 aatacctaat gagaaaattg ggaataaaat tagcaaaaat gctagaaatt ttttcttcat
    58981 ttttagtctc cttttccgaa tattctctca ttatatcaga aaaagtaaaa aaaggcaaat
    59041 ttttatattt ttcgtgtcag aaaatataac attgattttt ccttttcttt cttgaattgc
    59101 tattaaaaat tgctataata atactatata tagaagaaaa gaggacgggg atatgaagaa
    59161 caaaagaata tttaaagact tccaagcttc aaaaatgaat ttaaaccttt acacaagccc
    59221 cttgttagcc tttgtttttg tcttcatagg agagtttgtg gcttatactt tatatggtat
    59281 tagtttgtta gctctcatcg gacttgctag aaattttgga gaggctggtc aaaatcttgc
    59341 aagctacttg cagaccttgc atcagagctt gacggataaa acaagtgact ttcgtttaat
    59401 tttaggatta ctggcctttg gttttattct taacactgtg ttcagatgga caagaaaagt
    59461 tgagaaaaga cctattcgaa ccttgggatt ttatagagag aattgcctca gcaatcttct
    59521 gaaaggattt agtctaggcc tggcactttt tcttctgacc ttgttaagtt tagtggtctt
    59581 aggtcaatat cgtttggaat ccattcactt gaatccttat tatcttgcct ttgtcgtctt
    59641 tactatccca ttttggattt tacaggggac agcagaagaa gtggtggccc gtgcttggct
    59701 acttcctcaa ttggcctcaa gaaccaatct aaaactagct attcttatat ctagcctgtt
    59761 ctttaccctg cttcatatgg gcaattctgg cctcacccct ctatctctag taaatctctt
    59821 tttattcgga gttgccatgg ctctttacct tctcaaaact gatacagttt ggggtgttgc
    59881 aggtattcat ggtgcttgga attttgctca gggtaatctc tttgggattt tagttagtgg
    59941 tcaaccgtca ggaacgtctc tgatgacctt tttaccacaa ggcaatcaag attggctatc
    60001 aggtggttct tttggcatag aaggttccat tatgacaagt ctggtattac tactgctgat
    60061 tgtctatctt gctaataaat taaagaaaga aaatgaaagg atgtgacttc ggtccgtcct
    60121 tttcttcgtg aaaatactat aagtatgcta aaataggaat agcacatgga gagaggattc
    60181 ttatgatcaa tcacattaca gataatcaat ttaaactagt atcaaaatat caaccatcag
    60241 gagatcaacc ccaagctatc gagcagttgg tggataacat tgagggggga gaaaaagctc
    60301 agattctgat gggggcgact ggaacaggga agacctatac tatgagtcag gtcatttcta
    60361 aagtcaataa accaactctg gttattgccc acaataaaac tctggctggt cagctctatg
    60421 gggagtttaa ggaatttttc cctgaaaatg cagttgagta tttcgtatcc tactatgatt
    60481 attaccagcc agaggcctat gtcccttcta gcgataccta tattgagaag gatagttctg
    60541 tcaatgacga gattgacaag cttcgccact cagctacctc agcccttttg gagcgtaatg
    60601 atgttattgt cgtggcctca gtctcttgta tctatggttt gggttcgccc aaggaatacg
    60661 ctgatagtgt cgttagtctc cgtcctggtc tagagatttc tcgtgataaa ctcttgaatg
    60721 acttggtcga tattcagttt gaacgcaatg atattgattt ccaacgcgga agatttcgcg
    60781 ttcgtgggga tgtggtagag attttcccag cttcccgaga tgaacatgcc tttcgagtag
    60841 aattttttgg agacgaaatt gaccgtattc gtgaagttga ggctctgaca ggtcaggtgt
    60901 tgggagaagt ggatcattta gcgattttcc cagcgacaca ctttgtgacc aatgacgacc
    60961 acatggaagt tgccattgca aagattcagg ccgagttgga agaacaatta gctgtctttg
    61021 aaaaggaagg taaactgctt gaagcccagc gtttgaaaca gcggacagag tatgatatcg
    61081 aaatgttgcg tgagatgggc tataccaatg gggttgaaaa ttattctcgc cacatggatg
    61141 gacggagcga aggagagcct ccttatacgc ttctcgactt cttcccagat gatttcttga
    61201 ttatgattga cgagagtcat atgaccatag ggcaaatcaa gggcatgtac aatggagacc
    61261 gttcgcgtaa agaaatgctg gttaattatg gtttccgttt gccgtctgct ttggacaatc
    61321 gtcctctccg tcgggaggag tttgagagtc acgttcatca gattgtttac gtttcagcga
    61381 cacctggtga ctatgaaaat gaacagaccg agacagtgat tgagcaaatc attcgtccaa
    61441 cgggactctt ggatccagag gtggaagtcc gtccgactat gggacagatt gatgacctct
    61501 tgggtgaaat caatgcccgc gttgaaaaaa atgagcgtac ctttatcaca actttgacca
    61561 agaaaatggc agaggacttg accgactact tcaaggaaat gggtatcaag gttaagtaca
    61621 tgcactcgga tatcaagacc ttggaacgga cggagattat ccgtgacctg cgcttgggtg
    61681 tctttgatgt cttggtcgga attaacctgc tccgtgaagg aattgacgtt cctgaagtga
    61741 gcctcgtagc tattctcgat gctgacaagg aaggtttcct tcgcaacgaa cgtggactca
    61801 tccagactat tggacgtgct gctcgtaaca gtgaaggcca tgtcatcatg tatgcagaca
    61861 cggttaccca gtctatgcaa cgtgctatcg atgaaactgc ccgccgtcgg aaaattcaga
    61921 tggcctataa tgaagagcat ggtatcgtac cacagacaat caagaaagaa atccgtgacc
    61981 tgattgctgt gaccaaggca gttgctaagg aagaggacaa ggaagtcgac atcaatagcc
    62041 tcaacaaaca agagcgcaaa gaactcgtca agaaactaga aaaacaaatg caagaagccg
    62101 tcgaagtact tgactttgaa ctggcggctc agatccgtga tatgatgttg gaagtcaagg
    62161 ccttggatta ggggaatagt atgatttatt taagaaagtt aaagagagaa gatttgatgt
    62221 ctttatggga aatggcttat tcacaactta atccagtttg gaaacagtat gatgctccct
    62281 attatgatga ttatcagtat ttttcaaatt ttaaagaatt cgaactacaa aaatcagaat
    62341 ccattttaag caactcaaat cgccttggta tttttgttga tgataaacta gttgggactg
    62401 tttcgcgtta ttgggtatgt aaacaaacaa gatggatgga attgggaatt ggtatttatg
    62461 ataaaaaatt ctggaacact ggtattggga aagttgctat gttgcagtgg atagatagga
    62521 cgtttcagga ttacttggag ttggagcatc tgggtttgac aacttggtca gggaatcttg
    62581 gtatgatgaa acttgctgaa aaattaagaa tgaaaaaaga agctcatatt ccaaaagttc
    62641 gttattatca aggtaaatat tttgatagta ttaaatatgg tattttgaga gaagactggg
    62701 agaaaacaaa tgacggttat tatcaaatca atggaaactc ctgaagagat agaaggtaag
    62761 ccccttgttc actggcaaac gtggagagag gcttatgatg gccttttgcc tgcagaattt
    62821 caggagacaa tgacattaga aagatgtcga ttctttagtc aaaagtatcc agaaaataca
    62881 ttgattgcga tggatggtat gaaggtagtt ggttttatca gttatggcaa ctttcgtgat
    62941 gagactattc aagctggcga aattattgct ttatatgttt taaaagacta ttatggaaaa
    63001 ggtatcgcac aaaagttaat aaaagcagct ttgattgctc ttaatcattt ttctgaaatt
    63061 ttcttatggg tattgaaaga taataagcgc gcaattgctt tctatcaaaa aatgggcttt
    63121 acttttgatg aacaagaaaa gatacttgaa cttggaaagc ccataaagga aaaacggatg
    63181 gtattctatt ctaaataatt ttaaaaagta gaagctaatg gtactggtat caagtctaaa
    63241 aatttaataa attagaaagt gagtaaattt atgtctcgag cacaattaac gattttaaca
    63301 aatatttgtc tgattgaaga tctcgaagct cagcgcgtgg tgatgcagta tcgcgctcct
    63361 gaaactaatc gctggtctgg ttatgccttt ccaggaggcc atgtagaaaa tggcgaatct
    63421 ttcgcagagt ctgtcattcg tgaaatctat gaagaaacag ggttgactat ccaaaatcct
    63481 caacttgtcg gcattaaaaa ttggccacta gatacaggtg ggcgctatat tgtcgtttgt
    63541 tataaggcaa ctgagttctc tggtaccctt cgctcttcag atgaaggaga agtttcttgg
    63601 gtgcaaaaag accagattcc aaacttggat ctggcctatg atatgctacc tttgatggag
    63661 atgatggaag catcggacaa atctgaattt ttctaccctc gccgtacaga agacgattgg
    63721 gaaaagaaaa ttttctaatc ctttactaaa taacctagct gatccaaggc ctcctcgata
    63781 tagtggaggt cttgttgtgt ttcggcttcg actaggtggt aatggacacc atctgtcaat
    63841 tcagataaag gtttaaaatc agaatgctcg acttgttcta gaaaatgttg aacgtctcgg
    63901 cggcaagaca gtttaagcaa ggtttcaatt tctccataaa cgggatggtc aatcaaagta
    63961 ttctggacat gcccaccatt atcgacaata gcaaggagtt cctgaccgat ttcttcaact
    64021 tcatgtttca ctttgaaaag tttgtgaaca taaggattgg tatcaatttg cttatagatg
    64081 tagccacgat tggtggatag gataggagcg ccatcggctc tcaaaattgc aatgtcctgc
    64141 acaatgacct gacgtgtgac atgaaaatgt tccgccaaac tttggccatt aagggcttta
    64201 ggagcttctt tcaagagttg gagcagggct tgtttgcgat cttttgtcat agcttttcct
    64261 tttaacggcg ttttcgaagc actttataga cagctagtgc taatgtatag tctaccatac
    64321 tatggataat tgtgccaaat ccaactagta caaatagaac atagaacatg ttttctacat
    64381 tggtacccga agttgcgtaa aaaaggacac aggctaatac ttcagcaagg gcatgaacaa
    64441 cagccaaaac aaaattgaaa acccaggaag attttggttt atctagggta tcggggaatt
    64501 tttgtaggta aagagatcct aaagcaccaa aagatatatg ggaaaaagcc cgaaaaacta
    64561 taaccatggg atagccagcc atcaaaaatc caaaactaga ggctaggatg acaaaaactg
    64621 ccatcaaggg cgacaagaac atggctataa aaatagcgat gtggctcccc aaagtatagg
    64681 aagcaggtgg aatgacaatc ttgaaaggca taacaattgg aatcaaaatc gcaatagccg
    64741 ttaaaagggc tgtcattgtc ataaattgtg tctttttccg tgtattcaca agaatctcct
    64801 ttttaactgc atatacacta gtatggtaca ataaaccaga caataaagca agaatttact
    64861 tgggtttata gatcattttt tagttaaaag ttatagtaga tggaaactag aatagtccac
    64921 ctctacttct aaaacattgt tagcgatttg actgtcctga tcgatttgtc ctgttcttat
    64981 ttcgttttac tatagtaaag atttcattaa aaagaaactg tatagagcaa aatctccacc
    65041 ttcaggtttg aaagcggaga ttgtttttat tttttcaagg tttgtagtcg tggaacaatg
    65101 gctagggtta gaattgcaga aatgaccaat tcagcaattg aatttgttga gataacggtt
    65161 gccagaagaa gttggatatt tccattataa acatttccaa ataggaagaa gattcctcca
    65221 aggacaaaga tagtatttgt caaggaacca agggctccag ctaaaatcag accagtcttg
    65281 tttttcatca gtttatagac taagtaagga gttaaaccaa tcaaaatacg tgggacgatg
    65341 gcaatgatag ctgagtagat gtttccgttt ggtacgaagg gagagaagag gtagcttgtc
    65401 ggtagaatcg taatcgtgtt aaccgtcaag ctaagtaatc ccatcaaaaa tccaagtgta
    65461 accccaactc gtggaccata aataatgctg gcaataatga caggaatatg aacaatggtc
    65521 ggtttgattg gaaatggaaa aaggttaaag ataagtgagc tcagaaagtg tatcacgagc
    65581 atggtagcaa aaaagatagc aatgggtgca atattagagc gttttttcat cgatagtttc
    65641 ctttattctt tctaaaataa ttgtgaggtc agctaaagct cctcgtccgt ggtctccaca
    65701 agctagtagg gattccttag gagcaatcag ctgatagccg taggtttcta atgttttcag
    65761 attattctga gttactggat ggtcatacat ttttgtattc atagcaggag ctattagttt
    65821 gggaatatga cttggtaggg ctagagctgt actggttacc atgttgtccg caaatccgtg
    65881 agctagtttt gcaatagtgt tagcagttgc aggtaccacg ataaataaat ctgctttttt
    65941 tccaagttcg atatgattga cctgatcagg atagggttcc ttcatgacat ccaagtggac
    66001 aggattctgt gagagtacct gtagtgtcaa aggttggata aactctgtag cagcctgagt
    66061 cattaagaca gtgacttgat ggccttgttt ttttagagaa ctgactaaat ctgccgactt
    66121 ataagaggcg attgaacccg ttacagccaa gagaatgttt gccatagttt tcctttctaa
    66181 gaatgatagg cttgaatttt ttcaaggagg agttctgcaa tttcttcttt agtctggact
    66241 gtttgaagct gatttttctc aacaaatata gctcggtgct gatctgctga aatttgagtc
    66301 aggtcattcg cgatgattaa atctgcttga ttcttgataa gactttttcg tgcaatgtca
    66361 accagatgat cttcggtaac atcaaccagc agtttgaaac caatcagatg aatagtggga
    66421 ttccattcct tgactaggga tatgattttg ggtgtctttt taaggaacaa aacctgaacc
    66481 tcatcagttg aagaaatctt ggcctgatga ttctgcttgc ttaaaaattc ttttagattg
    66541 gagctagcct gaacttcctc aagccctgtc atataaacag gagtgtagtc agaaacagcc
    66601 attgagtgga tcaagacctg ataatcctga acacgttctt gcatttctat tagaaggtcc
    66661 ttggtattgg taatttctcg aatacttagg ttaggatgag gctctggctt cagagctcgt
    66721 tttgtcgtaa ttaaacaaac ttcatgccct gcagaaagca aagtctctgt gataattttc
    66781 cccaagtgac ctgtagaatg gttagtgata gagcggacgc tatcgatagc ttcactggta
    66841 ccgcccgatg taactaaaat tttcatagca ctattgtaca caaaaataag cggtaagtaa
    66901 aatgaaagtg ataaattttt ggtaaaaacg aagatttact atagtttcaa actataaagc
    66961 catataaaat ttaagaaagg actctaaaag ccttaaaaac agagatattt acgaacgttt
    67021 agagagtttt aggatgttaa aaatcttgtt ttgtgatata atgaattatc atataagagg
    67081 ttagaggaat tttgaatgaa aacagatatt gaaatcgcac agagtattga gttgaagcca
    67141 attgttgatg ttgtagagaa acttggtatt tcttatgacg atttggagtt gtacggaaag
    67201 tacaaggcta aactcagctt tgataaaatt cgtgcagttg agagcaatcc agtcggtaaa
    67261 ttgatcttgg ttactgccat caacccaaca cctgcaggtg aaggaaagtc gacgcttacc
    67321 attggtcttg cggatgcctt gaacaagatt ggcaagaaaa ccatgattgc tatccgcgaa
    67381 ccgtctcttg gtccagtcat ggggatcaag ggtggtgctg ctggtggtgg gtatgcacaa
    67441 gttctgccaa tggaagacat caacctccac tttactggag atatgcatgc tattacaact
    67501 gccaacaatg ccctttctgc cttgattgac aaccacttgc accaagggaa tgagctggaa
    67561 attgatcaac gtcgtatcct ctggaaacgc gttgtggact tgaacgaccg tgcgctccgc
    67621 catgtgactg ttggtcttgg tggtcctcta aacggtattc cacgtgagga tggttttgat
    67681 attacagttg cttcagaaat catggcaatt ctttgcttgg caacggacat cgaggacttg
    67741 aaacgtcgtt tggcgaatat cgttattggt tatcgctatg accgtacgcc tgtttctgta
    67801 ggtgatttgc aggttgaggg tgccttggct ttgattttga aggatgctat taagccaaac
    67861 ttggttcaga caatttacgg tacacctgcc tttgtacacg gtggtccatt tgccaatatc
    67921 gctcatggct gtaactctgt tttggcgacg acaacagccc ttcacttggc tgattacact
    67981 gttactgaag ctggttttgg tgcggacctt ggtgctgaga aattccttga tatcaagaca
    68041 ccaaacttgc caacatctcc agatgcagtt gtcattgtcg caacccttcg tgcccttaag
    68101 atgaatggtg gtgtggctaa agacgctctg actgaagaaa atgtagaggc agttcgtgca
    68161 ggttttgcta acttgaaacg ccacgttgaa aatatccgta agttcggtat tccagcagtt
    68221 gtagctatta acgaatttgt atctgataca gaagctgaaa ttgcagtctt aaaagaactc
    68281 tgtgcctcaa tcgatgtacc agttgaattg gctagtgtct gggctgatgg agcagaaggt
    68341 ggagtagcac ttgccgaaac agttgttaag acaattgctg aaaatccagc taactataaa
    68401 cgtttgtacg ataatgccct ttctgtccaa gaaaagattg aaaaaattgt cactgaaatc
    68461 tatcgtggta gcaaagtgaa ctttgagaag aaagctcaaa cacaaattgc tcaaatcgtt
    68521 caaaacggtt gggacaaatt gccaatctgt atggctaaaa ctcaatacag tttctcagac
    68581 aatccaaatg cgcttggagc accagaaaac tttgaaatta ccattcgtga attggtacca
    68641 aaattaggtg caggcttcat cgttgcctta actggtgatg ttatgaccat gccaggtctt
    68701 ccaaaacgtc cagcagctct caacatggat gttgaaagcg atggaactgt actaggcttg
    68761 ttctagtgga ttgaaattga ctttaagtga gtttggaaat aatatccaag ctcatttttt
    68821 ctcagactgc aagcagttca tcaataagat ttatactctt cgaaaatctc ttcaaactac
    68881 gtcagcttca ccttgccgta ggtatatg
//
LOCUS       DAVBIC010000004        64849 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.004, whole genome shotgun sequence.
ACCESSION   DAVBIC010000004 DAVBIC010000000
VERSION     DAVBIC010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 64849)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 64849)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..64849
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.004"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            complement(36..317)
                     /locus_tag="VQ664_000231"
     CDS             complement(36..317)
                     /locus_tag="VQ664_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HET2788473.1"
                     /translation="MDTPDENGYVADDYRITYLEAHIKAMRDAIYKDGVDLLGYTTWG
                     CIDSVSAGTGEMNKRYGFIYVDRDNVGNGTLKRSKKKSFYWYMSFIAMV"
     gene            488..708
                     /locus_tag="VQ664_000232"
                     /pseudo
     CDS             488..708
                     /locus_tag="VQ664_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(825..1172)
                     /locus_tag="VQ664_000233"
     CDS             complement(825..1172)
                     /locus_tag="VQ664_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET2788474.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEVEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
     gene            complement(1283..3058)
                     /gene="spxB"
                     /locus_tag="VQ664_000234"
     CDS             complement(1283..3058)
                     /gene="spxB"
                     /locus_tag="VQ664_000234"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HET2788475.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAISKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            complement(3265..5508)
                     /locus_tag="VQ664_000235"
     CDS             complement(3265..5508)
                     /locus_tag="VQ664_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HET2788476.1"
                     /translation="MTEIVKASLENGIQKIRIRAEKGYHPAHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYIVVEKTR
                     KSLSLLQRFWITSIFTVPLVILMIGMLTGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDIIGDEVEVFGLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQSLHGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKENAKLAISQLKKRGLRTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QQSGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            complement(5518..5889)
                     /locus_tag="VQ664_000236"
     CDS             complement(5518..5889)
                     /locus_tag="VQ664_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HET2788477.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHANLPMGEEYVVEITPE
                     QVGEFGFACGMNMMHGKMIVE"
     gene            complement(5900..6295)
                     /locus_tag="VQ664_000237"
     CDS             complement(5900..6295)
                     /locus_tag="VQ664_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HET2788478.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTIQTLL
                     ARLVEKECLTRKKEGKSFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     regulatory      6479..6577
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            6661..7452
                     /gene="thiD"
                     /locus_tag="VQ664_000238"
     CDS             6661..7452
                     /gene="thiD"
                     /locus_tag="VQ664_000238"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HET2788479.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDVYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLESVFSDIPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSSARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEGMQRA
                     GRLILKEFGPQSVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     gene            complement(7661..8293)
                     /locus_tag="VQ664_000239"
     CDS             complement(7661..8293)
                     /locus_tag="VQ664_000239"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HET2788480.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARKVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPV
                     VAIGGLTSENIDQLMGTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(8286..9089)
                     /locus_tag="VQ664_000240"
     CDS             complement(8286..9089)
                     /locus_tag="VQ664_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HET2788481.1"
                     /translation="MQALTNPFPIGSSSLIHCMTNEISCEMLANGILALGCKPVMADD
                     PREVLDFTKQSQALFINLGHLSAEKEKAIRMAASYANQSSLPMVVDAVGVTTSSIRKS
                     LVKDLLDYRPTVLKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYPG
                     MSFLVTGPKDLIVSENQVAVLENGCTELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEVYE"
     gene            complement(9089..9613)
                     /gene="thiW"
                     /locus_tag="VQ664_000241"
     CDS             complement(9089..9613)
                     /gene="thiW"
                     /locus_tag="VQ664_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HET2788482.1"
                     /translation="MRKHQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFAERID"
     gene            complement(9618..10310)
                     /gene="tenA"
                     /locus_tag="VQ664_000242"
     CDS             complement(9618..10310)
                     /gene="tenA"
                     /locus_tag="VQ664_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HET2788483.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKELEINDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            complement(10321..10971)
                     /locus_tag="VQ664_000243"
     CDS             complement(10321..10971)
                     /locus_tag="VQ664_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ABC transporter permease"
                     /protein_id="HET2788484.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALNLSVVAFCILFMLY
                     YRRFKMLAWMIILAIFPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQKLHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAYGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            complement(10973..12358)
                     /locus_tag="VQ664_000244"
     CDS             complement(10973..12358)
                     /locus_tag="VQ664_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2788485.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHAQAFTLLVGSSGSGKSSLFQMI
                     AQVSSLPYSGQVLIDGSEVSQLSIVERVQTVGILLQNPNHQFTMESLFEELVFTMENI
                     GYHLQEIDSKIAEVVQQCRCKDILHRLIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELVYDGKTVILCDHDLSDYKAYIDHMVELRDGKLREVFQIPS
                     YEMTQVASKEVASSPELFHMNRVTGELGNRPLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGSITWKGSVLKKKKSLYRDLTGVVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLRHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            complement(12359..12919)
                     /locus_tag="VQ664_000245"
     CDS             complement(12359..12919)
                     /locus_tag="VQ664_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET2788486.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGFVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     regulatory      complement(13181..13269)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(13478..14107)
                     /locus_tag="VQ664_000246"
     CDS             complement(13478..14107)
                     /locus_tag="VQ664_000246"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HET2788487.1"
                     /translation="MFHKELLKLYFICGTTTCQGKNLYTVVEEALKGGITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIRNEEEFQQSKVEYVDYVGVGPVFGTQSKDDAGGTIGYEGLELMRKLL
                     PQMPLVAIGGIQTKHIKDIIKTNMDGVSIISAISYAKNIEKTVREMSEQ"
     gene            complement(14109..14891)
                     /gene="thiM"
                     /locus_tag="VQ664_000247"
     CDS             complement(14109..14891)
                     /gene="thiM"
                     /locus_tag="VQ664_000247"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HET2788488.1"
                     /translation="MTSLKLLKEKAPLVICITNDVVKNFTANGLVALGASPAMSEFPA
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVMIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEMAEKRPNGHLPGTFKVEFINALYEITDEDVKEFKRVK"
     gene            complement(15134..15802)
                     /locus_tag="VQ664_000248"
     CDS             complement(15134..15802)
                     /locus_tag="VQ664_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HET2788489.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENDYLEVTLHPVTKAFQDLMYSAVASSDYAHLLVMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAEWVQFLVDELNRVDKNREDLTELQQRWNQAVALELAFFDI
                     GYDV"
     regulatory      complement(16017..16105)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(16359..17495)
                     /gene="lctO"
                     /locus_tag="VQ664_000249"
     CDS             complement(16359..17495)
                     /gene="lctO"
                     /locus_tag="VQ664_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HET2788490.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCDVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDRRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGAQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
     gene            complement(18120..19610)
                     /gene="lysS"
                     /locus_tag="VQ664_000250"
     CDS             complement(18120..19610)
                     /gene="lysS"
                     /locus_tag="VQ664_000250"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HET2788491.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYANLDKEQLHDKNETATIAGRLITKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINEPFKRVHMVDAIREITGVD
                     FWQDMTLEEAKTIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            complement(19738..19884)
                     /locus_tag="VQ664_000251"
     CDS             complement(19738..19884)
                     /locus_tag="VQ664_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HET2788492.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAGDTF
                     TSFQ"
     gene            20110..20778
                     /locus_tag="VQ664_000252"
     CDS             20110..20778
                     /locus_tag="VQ664_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006531263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET2788493.1"
                     /translation="MVEQYLPLYQKAFFLTLHIAVWGILGSFLLGLIVSIIRHYRILV
                     LAQVATAYIELSRNTPLLIQLFFLYFGLPRIGIVLSSEVCATLGLVFLGGSYMAESFR
                     SGLEAISQTQQEIGLAIGLTPLQVFYYVVLPQATAVALPSFSANVIFLIKETSVFSAV
                     ALADLMYVAKDLIGLYYETDIALAMLVVAYLIMLLPISLVFSWIERRLRHAGFGNPST
                     LSRK"
     gene            20738..21415
                     /locus_tag="VQ664_000253"
     CDS             20738..21415
                     /locus_tag="VQ664_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001154125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET2788494.1"
                     /translation="MQDSGIQVLFQGNNLLRILQGLGVTIEISILSVLLSMMFGTVMG
                     IIMTSHSRIIRFLTRLYLDFTRIMPQLVLLFIVYFGLARNFNINISGETSAIIVFTLW
                     GAAEMGDLVRGAITSLPKHQFESGQALGLTNVQLYYHIIIPQVLRRLLPQAINLVTRM
                     IKTTSLVVLIGVVEVTKVGQQIIDSNRLTIPTASFWIYGTILVLYFAVCYPISKLSTH
                     LEKHWRN"
     gene            21416..22173
                     /locus_tag="VQ664_000254"
                     /pseudo
     CDS             21416..22173
                     /locus_tag="VQ664_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
     gene            22185..23046
                     /locus_tag="VQ664_000255"
                     /pseudo
     CDS             22185..23046
                     /locus_tag="VQ664_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765255.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine ABC transporter substrate-binding
                     protein"
     gene            complement(23126..23773)
                     /locus_tag="VQ664_000256"
     CDS             complement(23126..23773)
                     /locus_tag="VQ664_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2788495.1"
                     /translation="MNEIIILKNIELKLKKTCVFQNLNFSCKQGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(23770..24468)
                     /locus_tag="VQ664_000257"
     CDS             complement(23770..24468)
                     /locus_tag="VQ664_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2788496.1"
                     /translation="MGKLSSHMWRLNKIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAVVYRRRASDFFMEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLPNWDIGVLFIVDSLNACVLVLFCFMLYALG
                     ANVQMNFACVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDVGGDLFLQLLFLVFLFQ
                     SIFYFTRQKRRFIE"
     gene            complement(24478..25230)
                     /locus_tag="VQ664_000258"
     CDS             complement(24478..25230)
                     /locus_tag="VQ664_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2788497.1"
                     /translation="MKQFVQFYKKDFLSVLVYFILLLSCVLSSTVYLLRCRQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFYLMNNYFNRLECRIRLKSIKHFTSFSFKLA
                     ALSTGIWTATLFLLIFLIAFSNGFSFSLEIKEVDFLREFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLNNGIIGLLPIFQYMV
                     NSNPYALIYWLTLLSIIIPLTVFSVHRNWRRV"
     gene            complement(25230..25994)
                     /locus_tag="VQ664_000259"
     CDS             complement(25230..25994)
                     /locus_tag="VQ664_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2788498.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKKYLAIVG
                     STAIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQLLYSLVTTLW
                     YGVWGAVFSIFGLASALLVKKKIGAIFIPVAYMMVGGIFWAILGLSYLEPVTTLALGY
                     QKDISLSLVSGHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            complement(26090..26493)
                     /locus_tag="VQ664_000260"
                     /pseudo
     CDS             complement(26090..26493)
                     /locus_tag="VQ664_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829085.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(26673..27305)
                     /locus_tag="VQ664_000261"
     CDS             complement(26673..27305)
                     /locus_tag="VQ664_000261"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HET2788499.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVEAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYRELIHLAQEEGYITPEGLDLLKRFKEDQENWQEG"
     gene            complement(27339..28040)
                     /gene="pyrF"
                     /locus_tag="VQ664_000262"
     CDS             complement(27339..28040)
                     /gene="pyrF"
                     /locus_tag="VQ664_000262"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HET2788500.1"
                     /translation="MREHRPIIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKVLSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QVIKQATNPDFICLTPGIRPAGVAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHAIKDEWTQNWN"
     gene            28361..28453
                     /locus_tag="VQ664_000263"
                     /pseudo
     CDS             28361..28453
                     /locus_tag="VQ664_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011516271.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(28775..29488)
                     /locus_tag="VQ664_000264"
     CDS             complement(28775..29488)
                     /locus_tag="VQ664_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2788501.1"
                     /translation="MLKRFLALVWLRCQIILSNKSILLQVLVPFAFTYFYKYLMETQG
                     KVNDQQALVLLMMCLPFSLALAVGSPITIILSEEKEKYNLQTLLLSGVKGSEYILSTM
                     FLPFLLTFVIMGTTPLILGVTIVHTFNYITIVLLTSLSIILFYLLIGLTAKSQVVAQV
                     ISLPAMILVAFLPMLSGLDKTVAKITDYSFMGLFTKFFTKWEGFSWNKTLIPNLTLLI
                     WIVLLLTLITITIRKKKIS"
     gene            complement(29481..30176)
                     /locus_tag="VQ664_000265"
     CDS             complement(29481..30176)
                     /locus_tag="VQ664_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2788502.1"
                     /translation="MTGQFLADKGQSIILGQKSQNLTSGELKRIGLVSDTSGFYEKMS
                     LYNNLLFYSKFYNISKSRVDNLLKRVGLYDSRKMVAGKLSTGMRQRMLLARALINKPA
                     VLFLDEPTSGLDPTTSRTIHELILELKTAGTTIFLTTHDMNEATLLCDYVALLNKGKL
                     VEQGAPSELIQRYNKDKKIKVTDYNGNQITFDFTSLEQVSQADLENIFSIHSCEPTLE
                     DIFITLTGGKLNA"
     gene            complement(30516..31848)
                     /locus_tag="VQ664_000266"
                     /pseudo
     CDS             complement(30516..31848)
                     /locus_tag="VQ664_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812020.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
     gene            complement(31832..32630)
                     /locus_tag="VQ664_000267"
                     /pseudo
     CDS             complement(31832..32630)
                     /locus_tag="VQ664_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001824573.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M50 family protein"
     gene            complement(33420..34619)
                     /gene="divIB"
                     /locus_tag="VQ664_000268"
     CDS             complement(33420..34619)
                     /gene="divIB"
                     /locus_tag="VQ664_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HET2788503.1"
                     /translation="MSKDKKNEDKEILEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQEDSESAKEESEEKVASSEADKEKEEKEEPES
                     KEKEEQDKKLSKKATKEKPAKAKIPGIHILRAFTILFPSLLLLIVSAYLLSPYATMKD
                     IRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIKVFV
                     SELAQISPELKAAIQKVELAPSKVTSDLIRLTMNDSDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVVDMEAGIYSYTVADKLIMEAEEKAKQEAKEAEKKQEEEQKKQEEESNRNQT
                     TQRSSRR"
     gene            complement(34629..35687)
                     /locus_tag="VQ664_000269"
     CDS             complement(34629..35687)
                     /locus_tag="VQ664_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HET2788504.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVCWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLSKVEHVGA
                     VAKVSDQKNPEPDELVDIQSHFNHKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELSQNLFRVDYVTDLYQPLMELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQLENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            complement(35689..37041)
                     /locus_tag="VQ664_000270"
     CDS             complement(35689..37041)
                     /locus_tag="VQ664_000270"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HET2788505.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQSLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYNNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIASD
                     KDTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGSFSEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLAKDLTSKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRGVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            complement(37145..37786)
                     /locus_tag="VQ664_000271"
     CDS             complement(37145..37786)
                     /locus_tag="VQ664_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2788506.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTSGCGKTTFL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNCVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTTSLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            complement(37788..39809)
                     /locus_tag="VQ664_000272"
     CDS             complement(37788..39809)
                     /locus_tag="VQ664_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HET2788507.1"
                     /translation="MKKLFILLSTFFLSFFLAWIIVLRAPQYLYASYDSVSLLRVKKD
                     TQEPTREVFEQELENFANSEQSLIARRIVEPSKDGTTHFTYATYGQGTLPKEFQEASQ
                     ESRERSDPLNSYLLLSGSLTKEKLADKLGDLGYKASADRKIPPYFLAFRILLNPLILI
                     SLAIFGLSFFALVIITRIKEMRAAGIKLFSGQTLLSIMGHSLSTDIKWLLLSALLSFL
                     GGGVVLFSQGLFYPILLATYGFGISFYLLFLLAISILLMLLYLMSLSYKALVPVIKGR
                     LPLKRLMILTLLCQLVAVFTVGYAVKTGLMSYQRLKELEISKQAWQDRADYYQISFGL
                     GDRGKDTENQSKWYAFAKEAIEEEQALYVKDNLLHFANPQGKNEQGETLDTYSPDANT
                     LYVSPSYLDKEKVVVDAETKQKLAHLQKGEFILLLPEHLRSREAELKKVFEERLSYYG
                     KSGEEASAPLDYEMKAHVSYLSMGEKRFVYNNGENPVSTQYLTDPILVVFTPTSTGDS
                     FISLSSWSINAGKQLFIKGYESGLELLKKAGIYEQVSYLKEGRSVYLTRYNEVQTETA
                     TLILGAIVGIASSLLLFYSVNLLYFEQFRRDILIKRISGLRFFETHAQYMVSQFASFV
                     FGASLFILSSRDLVIGLLTLLVFLASAVLTLYRQAQKESRVSMTIMKGK"
     gene            complement(39880..40179)
                     /locus_tag="VQ664_000273"
     CDS             complement(39880..40179)
                     /locus_tag="VQ664_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HET2788508.1"
                     /translation="MKTKKHRLLALALISSFTLLGAASAAVQYPDGGVWTYGEGSGGG
                     WAFSNYYHGKKYHYSSLVSRWNSHSDKGEASAGKTSYAWIWTKWGEQVAFYCDYD"
     gene            complement(40545..40799)
                     /locus_tag="VQ664_000274"
     CDS             complement(40545..40799)
                     /locus_tag="VQ664_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HET2788509.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLILAYFSVRDITLMPVKKSKRR"
     gene            complement(40819..42660)
                     /gene="typA"
                     /locus_tag="VQ664_000275"
     CDS             complement(40819..42660)
                     /gene="typA"
                     /locus_tag="VQ664_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HET2788510.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            42822..43547
                     /locus_tag="VQ664_000276"
     CDS             42822..43547
                     /locus_tag="VQ664_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase"
                     /protein_id="HET2788511.1"
                     /translation="MRLDNLLAQEKVSRKAMKQALLRGEILVDGCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVQVNELLTPDHIQAFQKGIVFLDGTVC
                     KPAKLEILSASPSLSQASITISEGKFHQIKKMFLSVGVKVTSLKRIQFGDFTLNPDLA
                     ESNYRPLNQKELQIIKNYLEMSR"
     gene            complement(43587..43814)
                     /locus_tag="VQ664_000277"
     CDS             complement(43587..43814)
                     /locus_tag="VQ664_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2788512.1"
                     /translation="MKEKKKNPLFVGILSIILGLLFPIVGLILGIIGLVLAISYQKES
                     QLDYKIEKILNILGIVISVVNWIVAIALIFR"
     gene            complement(43903..44283)
                     /locus_tag="VQ664_000278"
     CDS             complement(43903..44283)
                     /locus_tag="VQ664_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET2788513.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNEEFEALIRTGQ
                     LIDLRDPAEFHRKHILGARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            complement(44283..44552)
                     /locus_tag="VQ664_000279"
     CDS             complement(44283..44552)
                     /locus_tag="VQ664_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HET2788514.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            44616..45524
                     /locus_tag="VQ664_000280"
     CDS             44616..45524
                     /locus_tag="VQ664_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HET2788515.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLAHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            complement(45578..46333)
                     /locus_tag="VQ664_000281"
     CDS             complement(45578..46333)
                     /locus_tag="VQ664_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HET2788516.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEADAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(46354..47283)
                     /locus_tag="VQ664_000282"
     CDS             complement(46354..47283)
                     /locus_tag="VQ664_000282"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HET2788517.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTIRPRKVSKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTDASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            complement(47298..47921)
                     /locus_tag="VQ664_000283"
     CDS             complement(47298..47921)
                     /locus_tag="VQ664_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HET2788518.1"
                     /translation="MTDIKTLALKYGGYTSLDKVYLDQLLAGKTEQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKPFIRLNLSGKSFGFCY
                     ESDGFGRIFSENEEKISDDLLFEIAQIFSHQLVFEESGKIYMKPVKDEEVVSLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            complement(47914..49152)
                     /gene="hflX"
                     /locus_tag="VQ664_000284"
     CDS             complement(47914..49152)
                     /gene="hflX"
                     /locus_tag="VQ664_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HET2788519.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDG
                     EVITGYISEKNKWRLEEFYD"
     gene            complement(49145..50029)
                     /gene="miaA"
                     /locus_tag="VQ664_000285"
     CDS             complement(49145..50029)
                     /gene="miaA"
                     /locus_tag="VQ664_000285"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HET2788520.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKCFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVPHHLIDVREITESYSAFDFVSEAKMTIEDIHSRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVEQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQEILYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTLEEARESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            50150..50320
                     /locus_tag="VQ664_000286"
     CDS             50150..50320
                     /locus_tag="VQ664_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001051775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HET2788521.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            complement(50368..51207)
                     /locus_tag="VQ664_000287"
     CDS             complement(50368..51207)
                     /locus_tag="VQ664_000287"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HET2788522.1"
                     /translation="MTKADTIFKENIERILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPIITLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRVDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(51304..52263)
                     /locus_tag="VQ664_000288"
     CDS             complement(51304..52263)
                     /locus_tag="VQ664_000288"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HET2788523.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDRDKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPISCTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENTFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            complement(52390..53388)
                     /locus_tag="VQ664_000289"
     CDS             complement(52390..53388)
                     /locus_tag="VQ664_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HET2788524.1"
                     /translation="MNKRLFLKMSLVTLPILALFSQPVLAEENIHFSSCKEAWANGYS
                     DLHEGEPGYSAKLDRDHDGVACELKNAPKGAFKAKQAATTQTDTTSSTASGWVKQDGS
                     WYYFDGNGNLVKNAWQGNYYLKADGKMAQSEWIYDSSYQAWYYLKSDGSYAKNAWQGA
                     YYLKSNGKMAQGEWVYDSSYQAWYYLKSDGSYARNAWQGNYYLKSDGKMAKGEWVYDA
                     TYQAWYYLTSDGSYAYSTWQGNYYLKSDGKMAVNEWVDGGRYYVGADGVWKEGQASTA
                     SSSNDSNSEYSAALGKAKSYNSLFHMSKKRMYRQLTSDFDKFSNDAAQYAIDHLDG"
     gene            complement(53438..54055)
                     /locus_tag="VQ664_000290"
     CDS             complement(53438..54055)
                     /locus_tag="VQ664_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET2788525.1"
                     /translation="MKLIFLHGLGQSAESWKEVRNLLTDYPSEAIELFPSGVSNYQQA
                     KERVYQHLAQETEPFVLIGLSLGAALTLELSSYDLPNLRALILSGCPLKLAGNILFYL
                     QLLIFKLLPKRVFEKQGADKTLMVGVSEELKTLDLTDIAGTCSYPTLLICGSKDKPNL
                     SSMKALHRLLTDSQFQIIPDGPHVLNKAKPKEFVEKTRSFLELLK"
     gene            complement(54056..55777)
                     /gene="pabB"
                     /locus_tag="VQ664_000291"
     CDS             complement(54056..55777)
                     /gene="pabB"
                     /locus_tag="VQ664_000291"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HET2788526.1"
                     /translation="MHRKTVIDFRTLGERYTFAQPIKELKTRNVEEVADLLAQVESYQ
                     EQGYYVVGYVSYEAAPAFEEKLAVHKDPLLGEYLLYFTVHDSVETSPIPLTYEDIDLP
                     SNWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLSANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFRSLFPCGSITGAPKIATMEIIKDLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGEISQKNLLFED
                     QHLERLRKASRYFAFPFDAEDLGHKIEEECQDCEANRDYRLRISLSKSGEIEVNRQVL
                     TPLSTSFCQAQVCLQEAALNQSFTYFKTTHRPHLSLGEQEKIYHNKSGELLETSIGNL
                     VLKIAGKLYTPPIRLGILPGIYRQYLLETGQVEEKVLTLADLTQAEAIYGCNAVRGLY
                     ELSLEEN"
     gene            complement(55846..61533)
                     /locus_tag="VQ664_000292"
     CDS             complement(55846..61533)
                     /locus_tag="VQ664_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HET2788527.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQLPQTGTEASVLTAFGLLTVGSLLLIYKRKK
                     IASVFLVGAMGLVVLPSAGAVDPVATLALASREGVVEMDGYRYVGYLSGDILKTLGLD
                     TVLEETSAKPGEVTVVEVETPQSTTNQEQARTENQVVETEETPKEEAPRTEESPKEEP
                     KSEVKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKSEEKVAVKPESQPSDKPAEES
                     KVEPPVEQAKVPEQPVQPTQAEQPSTPKESSQEDNPKEDRGAEETPKQEESTPDTKAE
                     ETVEPKEETKTAKGTQEEDYVGEALVPEQLPEYKVTEGTLVEESTTELDYKTETTEDP
                     TKYTDEETVLRNGEKGSQVTKTTYKTIGGVKTDQVLSTSTEVTKEPVNQQVIRGTKPI
                     EGTTVETREEIIPFETKEQEDDTLKRGTRQVTQEGVNDKKQITETYKTIRGEKTSDAP
                     TITETVIEKPQDKIIKNGTKELEKPTLEWAKTDKDVLKKSATASYTLTKPAGVEIKSI
                     KVALKDNTGTVVKEVTVEENNLQATLDNLKYYQGYTLSTTMVYDRGNGEETEILEDKE
                     VQLDLKKVEIKDIKETRLMKVDENGNETDSSLLETVPENLTSYYLKITTNHNKVTRLA
                     ITNIEEVTEEETSLFKVTASAPDLIQRDSNNSLSQTYTYYIEKPKASQNNVYYNFKDL
                     VDAMQKNPNGEFKLGSDLNATNVPTPSKSYVTGKFTGHLTSVDGKHFSIHNTARPLFD
                     RVEGGSIKNINLINVNINMPWANQLASLAQTVKNATVENIKVTGTIVGNNNVAGILDK
                     LDDAGIMTNVAFIGKVQSVGDKGWNLAGIASEIYRGNLNKAYADVELKGLNTRAGAIV
                     GHLAHDFNPRDVGAWSNVRNSVAKGTIDVARGDVGGLIGKDWPWGTIDNNISLVNVKR
                     GDIFFGSNDMDDEFVSNWIKPNNATVIGVSSGDKTHKQSSKIKEISQVEADKKIKDMG
                     ITADTFEVTEHLVDKLNRRILRDEEYKTIQDYNANRELVYRNVEKLQPFYNKEWIVNQ
                     GNKLTTDSPLMNKEVLSVTAMKGNDFITDLTDADHIMVHYADKTKDIFTISPKDSQVK
                     QVKEYSVAELGEVVYTPNMVVKDRADLISAIEGILSPIELQSDPIYQRLGRTGDNRVN
                     AIKNLYLEESFKEVKDHLNTFVTKLVENEDHQLNTDEAAKRALIKKIEDNKAAVLLGL
                     TYLNRYYGVKFDNFNIKELMLFKPDFYGKNVSVLDRLIEIGSKEDYIKGSRTQESFRE
                     VVAKNTLSGNLHDFLTYNMKLFTNETDINVWFKKAIENNAYVVEQPSTNPAFANKKYR
                     LYEGLNNGQHGRMILSLLNLKDAHLFMISTYNTISFSSFEKYGKDTEEKRESFKSEIN
                     KRAKEQVNYLDFWSRLATDNVRDKLLKSQNVVPTPVWDNHGAPGGWPDRFGHRKDKPD
                     YAPIREFFGRIDKYHDYKYGYGAYAYIFADPQPMDAVYFVMSDLISEYGTSAFTHETT
                     HVNDRMAYLGGHRHRQGTDLEAFAQGMLQTPAEHGHQGEYGALGLNMAFERSNDGNQW
                     YNPDPTKLQTRDQIDHYMKNYNEAMMMLDYAEAEAVLPKVKGDNSKWFKKIDRETRRP
                     MDRNKLSGPHQWDKVRDLIDAEKTTNLETIDDLVNNNFMTIHGNPGNKVFHPEDFGTA
                     YVNVNMMAGIYGGNTSQGAPGSLSFKHNAFRMWGYYGYEHGFIDYVSSKHQGAANKEN
                     NGLLGDDFIIKKVSNNQFSNLEDWKKQWYGEVLTKSKKGFAPIEINGTQISTYEQLKT
                     MFDEAVTKDLTELNDSSIKDKYRNTVVLKSKVFKALLKNTDGFSGDLFTAPQA"
     gene            complement(61555..62118)
                     /locus_tag="VQ664_000293"
     CDS             complement(61555..62118)
                     /locus_tag="VQ664_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HET2788528.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGVLFVLGLSSSEVLGGQIG
                     KESSQEIGELIVETILGILGSRGIHLAVQGCEHVNRALVVERQVAEQFDLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALASRPKLIGGARAHYPQDAIRKS"
     gene            complement(62234..63925)
                     /locus_tag="VQ664_000294"
     CDS             complement(62234..63925)
                     /locus_tag="VQ664_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET2788529.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIETGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VAFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYQMKIDSRPQKGTKVEIYINRIETS"
     gene            complement(63922..64659)
                     /locus_tag="VQ664_000295"
     CDS             complement(63922..64659)
                     /locus_tag="VQ664_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2788530.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
BASE COUNT        19547 a        14065 c        11433 g        19804 t
ORIGIN      
        1 ataaaaatag taaacaaatg tgctctactc gatgcttaca ccattgctat aaatgacatg
       61 taccaataga aggacttctt cttgctacgt ttgagagtcc catttcctac attatctcga
      121 tctacataga taaagccata gcgcttattc atttcccctg tgccagctga aaccgaatcg
      181 atacagcccc atgtcgtata accaagcaag tcaaccccgt ctttgtaaat ggcatctcgc
      241 atggccttga tgtgggcctc taagtaagta atccgatagt catctgctac ataaccattc
      301 tcatccggtg tatccatagc accgagtcca ttttctacga taatactata ctaaaatcaa
      361 aaagcattat ataatagtga tatgaaatca actaaagaag aaatccaaac catcaaaaca
      421 ctttttaaag actctcgtac agctaaatat cataaatgcc ttcaaatcat tctatttcgt
      481 ctgatgggca aatcttataa agactccgac taatattggt tttgcattta ttcctccata
      541 cacaccagag atgaacccat cgaacaagtg tggaaagaga ttcataaacg tggatttaag
      601 aataaagcct ttcgaacttt ggaagatgtc atacaaggac tggagaagga ggtgataaag
      661 tccatcgtta atcggagatg gaatagaatg ctttttgaaa gcagatgagt attatatgca
      721 atttctttat ataaaaagac cggattgctc cgatctttca atagttcata ttctcaattt
      781 ctattttaaa aatagctaag gttaacgtca aatgactacg cgacctattt catacgataa
      841 aaatcaagca ctagaccagc aggtccttga actaataagg actctgttcc ccaatcggtt
      901 acagttggtc cgtgtaaaac ctttatacca agctcattca accgtttgta gttctggtct
      961 acatcctcaa cctcgatatg aataatgatt cctgactgaa agttttccaa aggaaccaaa
     1021 tgattttgtg acaacataag gcagtgacta ccaatcgtaa actgagcaaa accatcatca
     1081 gcataatctg cctttttatc caaaatatgc tccaagtcag cacagacttg gggaacattt
     1141 gaaacgataa tatctaattg atttaaattc atttactctc ctccataaaa agaccgaatt
     1201 gctccgatct tttaaagttc tgctctatga aaatcaaaga ataaagtcta caagtttcat
     1261 atttgatttt cggcgagagg aattatttaa ttgcgcgtga ttgcaatcct tcttcttcca
     1321 agaagagacg gaatggtacg agttcttctg cttcgtattt ttccttgaag gctttgatag
     1381 cttcttctga gtgaagtttt ggatccaatt caagtacttc tactggaagt ggacggtgtt
     1441 gagtgatgcg agcatcgatg acaacagttt taccttcttt gttcaattta acagcttctg
     1501 caacaactgc atcgatgtct tcgatacggt caactgtgaa tccaacagct ccttgagctt
     1561 ccgcaatttt agcgtagtca gcgtttgtga agtctacacc aaacaagtgt ttgtttgtat
     1621 cttcgtattt gttcttgatg aagccgtact cagcatttga gaagacaagg ttgataactg
     1681 gaaggtcgta ttgaacgttt gtgataacgt ctgggtagca catgttgaat gctccatcac
     1741 ccatgatgtt ccatacttgg cgatctggat tgtctttctt agcagcgata ccaccaggaa
     1801 gggcaatacc cattgtcgca aagagcggag atgtacgcca catattctta ggtgtcatgt
     1861 gaaggtgacg agtagatgtt tgagtagtgt tacctacgtc gattgagtag atagcgtctt
     1921 gatcagcatg tttgttgatt gcattgtaaa cttgatacaa ttgcaattca ccctcagttt
     1981 taccttcgag tttgttcatg taatcacgcc agttttggtt gttcttaacg tttgcacgcc
     2041 accatggagt tgattcaact gggtttactt tgtcaaggat agctttagct gcttgaccag
     2101 catcaccaag gattgaagcg tcaagggcat gacgtttacc aagtttgtaa gggtcgatat
     2161 cgacttggat gaatttttca gtgttcttga atgcttcgta aacttcagca aatgggaagt
     2221 ttgaaccaag gaaaagaact gtgtctgctt caaagaccac ttcgttggct ggtttccaac
     2281 caacacggta agcagaacct gtcaaacctt catagttcca ttcgaaagct tcaaagtttt
     2341 taccagttgt gatgattggt gctttgattt tacgtgacaa ttcagtaatc acttcaccag
     2401 ctttaacacc accaaatcca gcatagataa ctgggcgttc agcattgttc aagatttcaa
     2461 cagctttgtc gatttcaact tcgttcaaag caggagcgat gaatgagcgt tcgtatgaac
     2521 ctgaaccgta gtatgagttt tcgtcgattt cttggaaacc gaagtttact ggaatttcaa
     2581 caacagctgg acctttttta gaaattgcag cacggcaggc ttcgtcaatt acttttggca
     2641 attgctcagc gtaagctaca cgtttgttgt aaacagcgat accgttgtac attgggtttt
     2701 ggttaagctc ttggaaagca tccatgttca attcgttaac tggacgtgat ccaaggatcg
     2761 ctaggaatgg agtgttatcc atagctgcat cgtaaacacc gttaatcaag tgagtcgcac
     2821 ctggaccacc tgaaccaact gcaaccccga ttgagccgcc gaatttagct tgcataaccg
     2881 ctgcaagagc acctgtctct tcgtggcgaa cttgtaagaa gcggatatct ttgtcttcag
     2941 ccaaagcgtc catcaatgag ctgagtgttc ctgatgggat accgtagatt gtatctacgc
     3001 cccatgtttt caatacgtta agcattgctg cagatgcagt aattttccct tgagtcataa
     3061 tgataactct ccttcaattt ttttagattt ggagaatacg attacataga attggaaacg
     3121 ttctccaaat ttttactatt ccactgtatc atatttatgc tgacttttct aaaaatctgc
     3181 tcaaaactct ctattctcta ttctaataca gttttgaaag ttctgtcatt tctgttttat
     3241 aacaaagaaa tctagtcatt acttttagtc tattttacta aaatttaaca gaagggaact
     3301 ggtcagaaca gatacagaac taaaggccat ggctagacct gccaattctg ggttgagagc
     3361 cagtccaaca cctgaaaaga ctcctgctgc aatcggaatt ccgacaacat tgtagataaa
     3421 agcccagaaa agattgagta gaattcgatg aaaggttttc ttactcatat caaaggcacg
     3481 aaccactcct aaaagattat tggttgtcaa caccaaatct gctgactcga tggcgatatc
     3541 tgttccagct cccatagcaa tccccacatc tgctacacta agggcaggag cgtcattgat
     3601 accgtcccca acaaaggcta ctttccctga ctgttgcagt ttatggattt catgggcttt
     3661 ttcttctggc aagacgcctg caatgacctc ttcaattccg atttgatctg caatagcacg
     3721 cgccacacca gcattgtctc ctgtcagcat gactgttcgg agaccacgtt tttttagctg
     3781 actgatggct agcttagcat tttccttagg aatatcttgc aaagcaagca agcctttgat
     3841 ttcattgtca acagctaaga acacaactgt cttagcttct ttttctagtt cttctagttt
     3901 atcttgataa gtattagaaa tatccatacc atccagcatt ttagcatttc caagtaaaac
     3961 ttgttttcca ttgattcgcc ctgaaacacc tttcccgtgc aaggactgaa aattttcaac
     4021 agtttgaaac tcaagtccag cttcactcgc tcgcttaacg atagcctcag ccagtgggtg
     4081 ttgagaagca tcttccaagg aggctgccaa tccaaacact tctacttcgt cgccgatgat
     4141 atctgttacc acaggtttcc cttccgtcaa agtcccggtc ttatcaaaga caagagtttg
     4201 aactttctgg atttcctgta agacagttcc atttttgagg agaaccccca tcttggcact
     4261 acgtcctgtc cccaccataa gggctgtcgg tgttgcaagt cccaaggcac aaggacaggc
     4321 gataatcaaa accgccactc cgtagagaag agaggacaca aagctagctc caagcacgac
     4381 cacactatcc ctgagcaaga cgaaccaaac ccaaaaggtc atgattccta aaatgacaac
     4441 tactgggaca aaaatccctg aaatcttatc cgtcaagtcc tgaatcggcg cacgacttgt
     4501 ctgagctttc ttcacaaaat ccacaatctg agccaaaaca gtctctgagc caactttttc
     4561 tgctctaaag acaagcgttc cactatgatt gatggttgag ccaatgacag tatctccaac
     4621 tgtcttgtcc acaggcagac tctcacctgt caccatggat tcgtcaatac tagagacacc
     4681 ttctactacg acaccatcaa cagcaatctt ttcaccggga cgcactcgaa tcaggtcgcc
     4741 taccttgact tgttccaaag gaacttggac ataactatca tcactcaaga cttctgcggt
     4801 tttagcttgc aagtccagta atttctccac agcttgggac gtattttttc tcattttttc
     4861 ctcaaaaact gctcccaaaa gaacgaaaaa gaggataaat ccagcacttt cgaagtaaac
     4921 agggagacca gcaaagagag caactaggct atagaaataa gccactagag ttcccagcgc
     4981 aaccaaggta tccatgttgg cattgtgctt tttaaaactg gcccaagcac tctggatata
     5041 tggcttacct gcaactaaca taataggcgt tgttgctaga aaggttcccc aatgcatgac
     5101 ttgatgacta atgctacctg tcaacatccc aatcatgaga atcacaagag gcacagtaaa
     5161 gatactagta atccaaaaac gttgcaggag agatagagat tttcgagtct tctcaacgac
     5221 tatatagctt cccttttgca tcttcatgcc acaagaaaat tcatgtcgcc ctaattcttg
     5281 aggtgtaaaa cgaatgactt tctcctcatc tacgccgatt ggttccaaga taccttcttc
     5341 ttcaaacaga atttccttat aacagtttga aggagtagca cgatgaaagg taatctcagc
     5401 tggaattccc ttttgaagct ggatatgggc tggatgatag cctttttcag ctcggatacg
     5461 gattttttga atgccatttt ctaagcttgc tttcacaatt tctgtcatag tctccaccta
     5521 ctctacaatc atcttgccgt gcatcatgtt cataccacaa gcaaagccaa actctccaac
     5581 ctgctcaggc gtgatttcca ctacatactc ttcccccatt ggcaggttcg catgtacacc
     5641 aaaatctgga aaaacaattt gatccagaca tggtgaagga tccttgcggt caaagacaat
     5701 gcgtgctggc actgatttct tgaggacaat caactcagga gtatagcctc ccatgacttc
     5761 cactcgaatc tcttggtatc cgtttttttg ctgggctttt tgtccagatt tttcaggctt
     5821 tttgaaaaac caaaacaaga taaacgcgat aagggcaata caaataatgg ttacaatact
     5881 atttaacatg acgtctcctt tacatacaat tacatcttac ttctgttaca gcacttgatt
     5941 tcttctctga aatcacagct tccaagtctt ccaagtcagt ctgagtaaat tcacattcta
     6001 caatcaagtc agccaacaaa ttcctaatcc tacgggaaca aaccttgtct ttgatatctt
     6061 ggacaagtaa atcccgactt tggtctagag ttaaaagggc tgaataaaca aaggacttgc
     6121 cttctttttt ccgagtcaga cactctttct caaccaaacg agccaaaaga gtttgaatgg
     6181 tcgacttgga ccagtcgaac cgctctgcca aaaccctaat caaatctgta ctggtctgct
     6241 ccccctgcat ccaaataatc ttcatgacct gccattctgc atctgaaatc tgcattacca
     6301 tacctccaaa atctacattt gtcaattaca ctcatcagta tactcttaaa atctacattt
     6361 gtcaattata gaaataatat tttcttcgaa aaatagaatt ttaatcattt gaaaaacgat
     6421 ttgcagtcaa atattactat ataaacaata aaaatatgct atactaaaga aaaaagaaaa
     6481 caaccactag gggtgcgtaa agctgagatt aacgactgtt agatccctct gactcaatct
     6541 aggtaatgct agctgatgga agtggaaatg ataatgggga ctagcagtct tctattgcct
     6601 ttctaaaaca gactagcttg ttcttaagaa tacaaacttc agttggttgg gaggttttag
     6661 atgacttatt tacccgttgc tttgaccatt gcagggactg accctagtgg tggtgctggc
     6721 attatggcag atttaaagtc attccaagcg agagatgtct atggaatggc tgttgtaacc
     6781 agtcttgtcg ctcaaaatac cagaggtgtt cagctaatcg agcacgtttc tcctcaaatg
     6841 ttgaaagccc aattggagag tgtcttttct gatattccac ctcaggctgt aaaaactgga
     6901 atgttggcta ctactgaaat catggaaatc atccaaccct atcttaaaaa actggattgt
     6961 ccctatgtcc ttgatcctgt tatggttgct acaagtggag atgccttgat tgactcaagt
     7021 gctagagact atctcaaaac aaacttacta cctctagcaa ctattattac gccaaatctt
     7081 cctgaagcag aagagattgt tggtttttca atccatgacc ccgaaggcat gcagcgtgct
     7141 ggtcgcctga ttttaaaaga atttggtcct cagtctgtgg ttatcaaagg cggacatctc
     7201 aaaggtggtg ctaaagattt cctctttacc aagaatgaac aatttgtctg ggaaagccca
     7261 cgaattcaaa cctgtcacac ccatggtact ggatgtacct ttgctgcagt gattactgct
     7321 gaactagcca agggcaagag tctttaccag gcagttgata aggccaaggc ctttatcaca
     7381 aaagctattc aagatgcccc tcaactcggt catggttctg gtccagtcaa ccatacaact
     7441 tttaaagatt aagaaaaaaa ctctctagtt cccactttaa gggaattaga gagtttttat
     7501 actcttcgaa aatctcttca aattacgtca gcttccatct gcaacctcaa aacactgttt
     7561 tgagctgact tcgtcagtct tatctaaaac ctcaaggcag tactttgagc aacctgcgac
     7621 tagctttcta gtttactctt tgattttcat tgagtattaa ttaggaaaga atgtcatgca
     7681 actttgttaa aaaggcttgc gtttttgcct caatatcttc tgcttgcatc aaatcacgta
     7741 caacagctac accagctatg ccagtgccca taagctgatc aatattctcc gaagtcaagc
     7801 ctccaatagc aactactgga atggcaaccg tttggcaaat tgttttcaag gtcgatatca
     7861 gagtaatggg cgcattttcc ttggtggtgg ttgggaaaat ggctcctgta cccaagtaat
     7921 ctgcacctga tttctccgct tccagagctc ttttaaccgt tttagcggtg acaccgagga
     7981 ttttttcagg acccaagact ttgcgagcta ccgaaactgg taattcatca tctccgatat
     8041 gcagacctgc tgcatcaacc gcaagacaaa catccaaccg atcatcgatt atcaagggga
     8101 cctgataggc atctgttatt tccttgactt gttttgccag ttgataatat tgattggttg
     8161 tgagattttt ttctcgcaat tggactatgg taacccctga acggcaggcc gtctcaactt
     8221 ttgcaagaaa gctttccacg gaatcttgat agcgattggt taccagatat agtctaagtg
     8281 cttctctatt cataaacctc tcctttgatg gtatctagcc aattttcatc tcttcttagg
     8341 agcgaaagct gattgagtac ttggtaacga aattcttcca atcccattcc ttgaacaact
     8401 attttctcag cagcgatatt gagataagag actgctaagc aagaagcttc aaaaccagtc
     8461 tttccttggc tgagaaaaac ggctgttaag gctccaacca agtctcctgt ccctgttatc
     8521 cagtctaatt cagtacagcc attctccagt acagcaactt gattctccga aacaataagg
     8581 tccttggggc cagtaactaa gaaagacata ccaggatagg tctgacacca gtctttcaag
     8641 acttgaagca aatcctccgt ttcttgatct ttagcactcg catcgacccc aacgccgtgg
     8701 tgctttaatc caacaagact tcgaatttct gacatgtttc ctttaaggac cgtaggtcta
     8761 tagtctaaaa ggtctttaac taagctctta cgaatggatg aagtcgttac gccaaccgca
     8821 tctactacca tcgggagaga agattggttt gcatacgaag ctgccatgcg gattgctttt
     8881 tccttctcag ctgacaaatg ccccaaattg atgaagagag cctgactttg cttagtaaaa
     8941 tcaagaactt cacggggatc atctgccatg acaggtttgc atcccagagc caaaatccca
     9001 tttgccagca tctcacaaga aatctcattg gtcatacagt gaatgaggga actagagcct
     9061 ataggaaaag gatttgtcaa tgcctgcatc agtctatcct ttcagcaaag aaatatcctt
     9121 gcactttttt aaagaattcc tgcttgatta aaaatctaaa tgcaataaag gaaatcgctg
     9181 taccaatcaa ggttgctccg aaaaatcgag gagtgtagat aaaccaacta agcttagcag
     9241 ccgatcctgt aaagagcacc ataacaggat aggaaacaat agaaccaata atacctgttc
     9301 ccacaatttc tcccaaggca gaaaagtaaa attttcgacc gtacttataa aagagacctg
     9361 ctagaagggc tccaaaagtc gctcctgtga gagctaaagg cggaatccct tgagtcgtca
     9421 tacggataaa ggctgtcact gtagccatag ccaaggcata aacaggtccc atcatgattc
     9481 ccgctagaat attgactaca ctggacatcg gtgccattcc ctcaatccga aagataggtg
     9541 taaggactac atcaagggca atcatcatag ataaaatggt caatttgtga acttgtagtt
     9601 ggtgctttct catgtttcta ttcttctcct ttttctaaag actgtaaatc gctcttccat
     9661 gtctggtgtt ggtaagccat ctcccaaaac ttggcttcca tatgaacact gatgtggaag
     9721 gcatctagca ttttttgctt atctgtctca tcactttctc gataaagctg attgaccagt
     9781 gctccctcct ctctgatctg ttgctctaac tcatccgtaa tataagtttc aatccattgt
     9841 tgatagagag gatttggtga tggtttaaga ttaagtgatt tgcctatatc atggtataac
     9901 caaggacaag gaagcaagct tgcaaaagct atggctaagt tcggttctgc aaattgccta
     9961 taaatatgag aaatgtaatg ataacaggtt ggagcgattg gatgttgctc catttcctgg
    10021 tcgttgattt ccaattcctt gaaaaattgt tggcgaataa ataactcacc ctccactaaa
    10081 ccctgagcat tttgtttcaa gagtcttttc atctcttggt ttgaagtctt atcagccaaa
    10141 agatgataga tttctgagaa agccttcaga tagtaggcat cctgaatcag gtaatagcgg
    10201 aaaatggcag gttctaaatt cccctcttgt aattgtaaaa taaagggatg atgaaaggaa
    10261 gcctgccaag ctttcttgga taattccatc gcaatatctg taaattccat aataactcct
    10321 ttataaaaat agactggttt gaagcaataa aaagaaaagc aggtagatta attttgtttt
    10381 tttaggaata taaaaagtcc gatagctatt cttcaactgt gcatgttcgt catatccgta
    10441 agcagataga gctctcaggt aaagatggcg ccacctaaag actgtcatca gaaccttact
    10501 gtaaatcaag ggcgaccaaa aatgtagttt ttgaccacgt aataggcaag cttctttgag
    10561 ggacttgatt tcttgctgaa tgagaggaaa agaattgaat accacaatca aggcatagga
    10621 ccaagagcgt gatagcccct tttgagccaa gtacaagaga agctctttta gtgaaataga
    10681 ggaaacaaag acaaggccga tacaaactgt cacaaaggcc ctcgttccaa gcatgactgc
    10741 ctgtgaagca tctccgtgta actgaactgc ccagtagttg gcaaaagatg ggaaaatggc
    10801 aagtatgatc atccaagcta acattttaaa tcgacggtaa tagagcataa agagaataca
    10861 aaatgcgact accgaaagat tcagagcaat cgaaggaatg aaagatgttt ccaaggataa
    10921 aatcagcaag aagagactga taatcggtgt ctgggttgct actttgacca tactatctca
    10981 cctccccttg ggtattgcta ctctgagatg taagtggttt ggtaatggtc acttctttca
    11041 catgccgaag accctgacta gtcatctcaa tccaataatc aaccacagaa atcaaagggt
    11101 ctaaacgatg actaatgagc agaaaacttc ttccttgatt cctctcctcc acaatccact
    11161 tgcaaaaata atggcaggct ctatcatcca aacctgcaaa aggttcatct agcaagatca
    11221 cggaagcctt actggtcaag atggtcagga gctgaagaat tttttgctga ccaccactta
    11281 attgataggg actcttatcg actgcctgct ccaaatcaaa atatcgtaaa gcttgaaaaa
    11341 tccgctgatt tctttcagaa tcaggtccat ctaattgaag ctcctctcgc agactgactc
    11401 ggataaactg cttctcagct tcctgaacaa caccagtcag atcacgatac aaactctttt
    11461 tctttttcag gaccgaaccc ttccaagtaa tgctcccctt atacttttga aattgaagaa
    11521 tagaccgaaa gagggttgat ttcccgacac cattgtcacc caggatacag gaaatccctt
    11581 gatagaatgt gaaatcagca attgaaaaga gggggcgatt accaagctca ccagtcacac
    11641 ggttcatatg gaatagttcc gggctagaag caacttcctt tgaagcaacc tgtgtcatct
    11701 cataggaagg gatttgaaac acttccctta gttttccgtc tcttagctcc accatatggt
    11761 cgatataggc tttatagtca gataaatcat ggtcgcacaa aataactgtc ttcccatcat
    11821 agaccaactc ttttagaatc tccaatatct cgattctgct cttgcggtca atggaagcga
    11881 agggctcatc caagagatag accctaggat tcatggcaaa gaggacagcc agcgctgctt
    11941 tttgcttttc cccacctgat aagtgatgga tgagacggtg caagatgtcc ttgcaacgac
    12001 attgctggac aacctctgct attttagaat caatttcctg aaggtgatag ccgatatttt
    12061 ccatggtaaa aaccaactcc tcaaacaagc tctccatggt aaattgatga ttaggatttt
    12121 gcaagagaat accaaccgtc tggacacgtt cgacgataga aagctgactg acctcgctcc
    12181 catctatcag gacttgaccg ctatagggaa gagaactaac ttgggcaatc atttgaaaga
    12241 ggctggattt tccagaccca ctactcccaa ctaacaaggt aaaggcttgc gcatgaaaag
    12301 taaaatcaaa cggctcagag aagattgggg actgaatcgc tcgtagttcc agacccatct
    12361 atgcttttcc tccagttgca aactgatgat agagtttgac aatggcacga accaagatgg
    12421 tacagaagaa ataaacagaa ataaaacgta ccacaagcaa ggaaaggaca aacggaaggg
    12481 aaaaggcgta gtaacctaac ttaatgtatt catagacaaa gctaacaagc gtaatcccaa
    12541 tactattagc agttagagag agccaacttt catagcgatt cttagttacg ataaaaccaa
    12601 attcacttcc caaaccttga acaaagccag acaaaagagc tcctagacca aattggctac
    12661 cataaaggac ttcagcaagc gcagctagca cttctccaat cgttgcactt ccgactctcg
    12721 gaacaaagat ggcagcaatg ggcgcagcca tacaccagag accgaagagg atttcattgg
    12781 caaaggcctg caaaccaaga ggtgttaaga gtagactgag aatattatac acatatcctg
    12841 aaccaacgaa aaccccacca aaaaagatag acaagaaagc aagcaagata acatctttta
    12901 actgccattt tttcaacata aaaaactcct ttttttaaag aaaagtgggg cactcaagaa
    12961 gaccgaccta aatactttgt atagcagact gaatttagaa cagtacacaa gaacactaaa
    13021 atatttctag aaattaattt gaattttcta attgatttgt tcgcatctta tttcaatcta
    13081 ctatatcatc ttcatccagt ttcgtaaaag aaaaaactct aattacagat acaaattaga
    13141 gttcagctta caagattaga cagttctttt cgacatacga aaaaaacatt tcacatttcc
    13201 cttcgccagt cttaactgta tcaggttcaa tgggtatcat ctcagcctaa agcaccccaa
    13261 atgtctttat tatttaatta tgtgattatt ataacacaca ttttatacta gttcaagaaa
    13321 ttgaactgga aatacagcct tgcactcaca aagacagcag atctttcttt tgcaaaaaac
    13381 aaatgacctg tttgatgaat tagccattca agctgaatct ggacatagct ttttaaaaaa
    13441 ggaaaatcct acttacttag aatccaagga tagatatcta ttgttcactc atttcccgaa
    13501 cagttttttc tatatttttt gcatacgata ttgccgaaat gattgaaacg ccatccatat
    13561 tggtctttat aatgtcttta atatgtttcg tctgtatccc accaattgca actaaaggca
    13621 tttgtggcaa tagttttctc atcaattcaa gaccttcata acctatagta ccaccagcat
    13681 catcctttga ctgggtacca aatacaggcc caacacctac ataatctaca tattcaactt
    13741 ttgattgttg aaattcttct tcgtttctta tagaaagacc aattatttta tctggcatca
    13801 attttctaat ttcatcaaca ccaatatcat cttgacctac atgtacgcca tcggcgtcaa
    13861 tttccattgc taaatctata tcgtcattaa cgataaatgg aacattgtat tttttacaaa
    13921 gttctttaat ttggatagct agctcaagtt tttctaagcc ttctaaagca ccctcacctt
    13981 tttctcgaaa ttgaaataag gttataccac cttttaaggc ttcctcaacg actgtatata
    14041 gattttttcc ttggcaagta gtcgttccac aaataaaata tagttttagt aattctttat
    14101 gaaacatctt acttcactct tttgaattcc tttacatctt catctgtaat ctcgtataag
    14161 gcatttataa attcaacttt aaatgtccca ggaagatgtc catttggacg tttttctgcc
    14221 atttctccag cgatattgta aaccaacatt gctgtttcta atgatttcaa ttcttgacct
    14281 ttttctagtc cgataaagct tgctactaca gctcctaata agcatcctgt cccaatgact
    14341 ttcggcatca tagcactacc attatgaatc attaccactt ctccattaac agcaatggca
    14401 tccacttcac ctgttactac tattggaata ttgaacttct catttgctgc tagagcaatt
    14461 tcgtcaatat tatctacgcc cgcactatct actcctttag atgccacatc tattcctact
    14521 aaagaggcaa tctcgccagc atttcctcta atcgctgcta gtttataatt gttgattaga
    14581 tcatctgcta ctttttttct atattctcct gctccacagg ctacaggatc taaaactgct
    14641 gggacattat atttctctgc aattttcaga gcagcttggt ataatttcca attttcatct
    14701 gtcaatgttc ctatgtttat taataaacca ccagcatact ttaacaaatc ctctaaatct
    14761 gctggaaact cactcatggc tggtgaggcg cccagtgcta ctaatccatt tgctgtgaaa
    14821 ttttttacta catcattggt tatacaaatg accaatggtg ctttttcttt taataatttt
    14881 aaacttgtca tattgaaatc cttccttttc actttatacg atctactgat ttcgatttat
    14941 ttctatcttt cgttaagaat ttttttcatt tacattgaat gatttatact caatgaaaat
    15001 caaagagcaa actaggaggc taaccgcagg ttgctcaaaa cactgttttg aggttgtgga
    15061 tagaactgac gtggtttgaa gagattttcg aagagtctta cctcatcaaa tttgtaaata
    15121 tcatgagcct tctctagaca tcgtaaccaa tatcaaaaaa agctaattct aaagcgactg
    15181 cttgattcca gcgttgctga agttctgtca aatcttctcg atttttatcg acacgattga
    15241 gttcgtcaac cagaaattga acccactctg caaagaaagg acctctgtgg agattgatcc
    15301 attccgaatg aatatagact tcaggtaaag ccaaatcttt agaaccccag tctaaataga
    15361 gaccttctgc aatgaccagc atgaccaaaa gatgggcata gtctgatgaa gccaccgccg
    15421 aatacattag atcctgaaag gcttttgtta cagggtgcaa agtcacttct agatagtcat
    15481 tctctgctac ttttaactct ttaaaagcct tttggaaata accatcttca tctgcttcaa
    15541 gaaagcctag ttgcttggca aaacgaagct tggattcaag tttatctgcg tgagctacgc
    15601 aggcacccag catggataag aaggcatcaa agaagtgata atcttgaatc agatagtcct
    15661 ttaagacctt attctcaatt gtccccgcaa aaagttcctt aacaaaacga tgattgattg
    15721 cagcctgcca atccttctga ctgcttttta ataattctcc aacagtcaaa cctggctgaa
    15781 atgcatagtc ttgtgtttcc atatttactt ctcctctctt tacttgttag taattaataa
    15841 aacaccaaga aatatcaagc aaaatcgtaa ttccacttga tccttttaaa gcacatcgag
    15901 agcatttgca gagagctaac taaacaagcc tatccagttt atataaacaa aaaactccaa
    15961 ttacaatcaa gaattagagt tgacttacaa gattagatcg ttcatttcgc catacgaaaa
    16021 aacgtttcac atttcccttc gccagtctta actgtatcag gttcaatggg tattatctca
    16081 gcctaaagca ccccaaatgt ctctattatt taattactga accagtatag caaaaaatga
    16141 aagccctagc aagatatttg accgaaaaat atctttatat ataatatatt gaaactagaa
    16201 tagtacacct ctacttctaa aacattgtta gaaatcgatt tgactgtcct gattgatttg
    16261 tcctattctt atttcatttt actatagttt tcgatagcaa tttattcttc caatacacga
    16321 agaaaaacct ccacattcag tggaggcaat ctgttttatc aatacaattt taagtcacga
    16381 gggtcaactg ggaaggttgg gttgtatgga ttgtgacgga gcttaaagtg tttgacatct
    16441 tcaatggtct gagctccaga caattgcata actgtcttca attccgcatt caagtgttca
    16501 aagacttgac gcacaccgac actaccaccg agagccaagc cataaataac agggcgacca
    16561 atagctacca agtctgctcc tgaagccaag gctttaaaga cgtgttgacc acgacgaaca
    16621 ccagagtcaa agacaatcgg cacacgtcta tcaactgctt ctgccacttc ttgaagcgag
    16681 tcaaaggcag ctggtccacc gtcgatttga cgaccaccgt ggttggttac ccagatacca
    16741 gaagctcctg cagcaagtga acgttcaacg tcctcacggc attgtggtcc cttgacatac
    16801 acaggaagac cagagtattc agcgataaat tctacatcgc gtggagacaa gcgttgttta
    16861 gctgatttgt aaacaaagtc cattgattta ccagcacctt ctggcaggta ttcttcaaca
    16921 atcggcatgc caactgggaa gacaaaacca ttacgcttat ccacttcacg attcccccct
    16981 acagtagcat ctgccgtcaa gacaatcgct ttataacctt cagccttcac acggtccatg
    17041 atgtggcggt tgataccgtc atccttacta aagtaaaatt ggaaccaatg gggtgtccct
    17101 tgaagggctt cagaaatctc tggaaggtca acagtagagt aagagctggt tgtataaaga
    17161 gaaccaaact catgcacacc acgcgcagtc gccacttccc cctgttcatt tgccaattta
    17221 tgagccgcaa caggcgccat aatgattggt gaagatagtt tttcacctgc aaattcaatc
    17281 tctgtacttg gattttcaac atcgcaaagt gtatgaggaa cgatgagttt gtggttaaag
    17341 gcgcggatat tctctcttaa agtgaaagta tcttccgccc cactagcgat atagccaaat
    17401 gctgctttag gaataacttg ttgcgccatt ggctccaaat cataggtatt gatgaagtct
    17461 acatgacctt ctgcattgct tgttttgtat gacataaaat gccctccttg attaagtaag
    17521 cgtttgcttt ttactacaca actataataa ctcttttttc aatcattttc aagagttttg
    17581 cttaaaaacc atcttatttt ttcatacaat atactagccc tactttcctt aaactctaaa
    17641 ctttagtcta tattaagtga atcgttgaga ttttttgctg ccaggcattt gaactacttt
    17701 tttatttgcg gattctatct actaatacta taaaaaaaca agtgaataag acaccagaac
    17761 atcctctaat aggacctatg gacttatatc agtcccatat atactgttta agcaagatac
    17821 tatcctagtt gacgctaact tcctatccca cttattaatt ttttatttat agtgaatctg
    17881 aacaaatcaa ttggggaatc caagtcaatt tctagtactt tttgaacagt ttcagcgtac
    17941 tatcgtaaaa tgaaataaaa catgcacaaa ttgcttaggg aatttaaacc aatttctaac
    18001 aatgtcttag aaatcaaagt gtactatttc aacttcaata tactacactt cattttctcc
    18061 ttaaattcag tctctttttg aatcaaaaaa tcccctggta agagccagag gataagaatt
    18121 tatttcattg ttgggaagag caatacatca cggatagttg ttgtatcagt gaggagcatg
    18181 cagagacggt cgataccgat tcccaaacca cctgttggtg gcataccgta ttcaagagct
    18241 tcaatgtagt catagtcgat gcctgtcgct tcatcatcac caagttcttt ggctttagct
    18301 tgggcttcaa aacggctaag ttggtcgatt gggtcgttca actcagtaaa ggcattaccg
    18361 tactccttag tcatgataaa gagctcgaaa cggtcagtaa agcgttggtc ttcaggattt
    18421 ttcttagcga gtggagatac agctactgga tgtccataga caaaggttgg ttggattaaa
    18481 gtttcttcaa caaactcttc aaagaaggca ttgatgatgt gaccaacctc agtgtagtgt
    18541 ttctcaactg gaactttctt ctcagcagcg atagttttag cttcttccaa agtcatgtct
    18601 tgccagaaat cgacaccagt aatttctctg atagcatcca ccatatgaac acgcttaaat
    18661 ggttcgttaa tcttgatttc agtaccttgg tagttgactg ggccatcacc tttgactgat
    18721 ttagcagcgt gttggataat gccttcagtc aagtccatga tgtcttggaa gtctgcataa
    18781 gcttggtaaa cttcgataga agtgaactca gggttatgag tagcgtccat tccttcgtta
    18841 cggaagatac ggccaatttc atagacacgt tccataccac ccacgataag gcgtttcaag
    18901 tgaagctcag tcgcgatacg aagcaccatg tcaatgtttt gggcattgtg gtgggtgata
    18961 aatggacggg cagcagcacc accggcttca ttatgaagaa caggtgtttc cacttcaagg
    19021 aatccttttt ggtcaaggta acgacggatt tcagagatga tttttgaacg agtgacaaag
    19081 cgttcaaagc tttcacgatt agaaatcaag tcaaggtaac gtttacggta aattgtttca
    19141 acgtctgtca aaccatggaa tttctcagga agaggacgaa gagccttaga caagtgtgtg
    19201 atgtgggttg ccttgataga gagttctccc atatccgtac gcatcacttc accttcgaca
    19261 ccaaggaagt caccaaggtc tgcttttttg aagatttcgt agttttcttc accgacagca
    19321 tccttacgaa cgtagatctg aatctggcct tcgcggtctt gaaggtgggc aaaaccaact
    19381 tttcctttac cacgtttggt tatcaagcgt cctgcgatag tagctgtttc gtttttatcg
    19441 tgtaattgtt ctttatcgag gttggcatat ttatctttta attcttgtga atttgcagta
    19501 cgttcaaaac gttttccgaa aggatcgatt ccttgttcgc ggagcgcagc cattttttca
    19561 cggcgaacga tctgctggtc atttagttct tccatatgtt ctgtagacat gggatcctcc
    19621 tagttttact caaaattgaa tacgatgagt cattttttgc gatactccca ttttatcata
    19681 aataagcaag aaattcacgg ataatcttta aaaactaaaa agaacctgac gctaaaatca
    19741 ctggaaagaa gtgaaagtat ctcccgcccc actagcgata tagccaaatg ctgctttagg
    19801 aataacttgt tgcgccattg gctccaaatc ataggtattg atgaaatcta catgaccttc
    19861 tgcattgctt gttttgtatg acataaaatg tcctccttaa taagtaagcg tttactttgt
    19921 gtattacaaa aatatcttaa ctctttttca aaacttttaa aatattttgt ttggaaattt
    19981 cagaaatttt atgtctatga taaaaatcct tataacggca ataaaaaata gatattatcc
    20041 aaagaagatt ttaagtgcta caataactgt attatttcta gatgggaggt tctatttttg
    20101 gattgatcca ttgttgaaca atatctacca ctatatcaaa aggcattctt tctgaccttg
    20161 catattgcag tttggggaat tttgggatcc tttctgctcg gtttaatcgt tagtatcatc
    20221 cgacattatc gaatccttgt tttggcgcaa gtagcgacag cctacattga attgtcacgt
    20281 aatacgcccc ttttgattca actcttcttt ctctacttcg gtcttccccg aatcgggatt
    20341 gtcctatctt cagaagtctg tgcaacgctt gggcttgtct ttttaggagg ctcctatatg
    20401 gcagaatctt tccgaagtgg gctggaagcc atcagtcaaa cccagcagga gattggcctc
    20461 gctattggtc tgacacctct acaggtcttt tactatgtgg ttcttccgca agcaacagcg
    20521 gtggcactcc cctcctttag tgccaatgtc attttcctta tcaaggaaac ctctgttttc
    20581 tcagcagtgg ctttggccga cctcatgtac gtcgccaagg atttgattgg tctctactat
    20641 gagacagaca ttgcgctagc tatgttggta gttgcttatc tgatcatgct gctacccatc
    20701 tcactggtct ttagctggat agaaaggagg ctccgccatg caggattcgg gaatccaagt
    20761 actctttcaa ggaaataatc tcctgagaat cttacaggga ttgggcgtta cgattgagat
    20821 atccatcctg tctgtcctct tatccatgat gttcggaaca gtcatgggaa tcatcatgac
    20881 ctcccattct agaatcatac gatttttaac acgattgtat ctggacttta cccgtatcat
    20941 gccccagctg gtgctactct tcatcgttta ctttggctta gctcgaaact ttaatatcaa
    21001 tatctcaggt gagacttcag ctattatcgt ttttaccctc tggggagcag ctgaaatggg
    21061 agacttggta cgtggagcta tcacttctct ccctaaacat cagtttgaaa gtggacaggc
    21121 actcggcttg actaatgttc aactttacta ccacatcatc atcccacaag tcttaagaag
    21181 actgctaccg caggctatca atcttgtcac tcggatgatt aaaaccactt cattagttgt
    21241 tttgattggg gttgtggaag tgaccaaagt tggacaacaa atcatcgata gcaatcgcct
    21301 gaccatccca actgcttcat tttggattta tggaaccatt ctagtcttat atttcgcagt
    21361 ttgctaccct atttccaaac tatccactca cttagaaaaa cattggagaa actaaatgtc
    21421 tgaaactatc ttagaaatca aggaactaaa aaaatccttc ggagacaatc ccatcctcca
    21481 aggactttct ctagaaatca aaaaagggaa gttgttgtca tcctagggcc atctggttgt
    21541 gggaaaagta ccctccttcg ttgcctcaac ggcttagaaa gtattcaagg tggagatatt
    21601 cttctggatg gtcagtctat cgttgaaaat aaaaaagatt ttcacctagt tcgccaaaag
    21661 attggcatgg tctttcaaag ttatgaactc tttccccatc tggatgtctt acaaaacctc
    21721 atcctaggcc ctatcaaagc tcaaggaagg gacaagaaag aagtaacgga agaagctttg
    21781 caattactag agcgtgtcgg tttgctggat aaacaacata gctttgcccg tcaattatct
    21841 ggtggacaga agcaacgtgt tgcaattgtc cgtgccctcc taatgcatcc agaaatcatc
    21901 ctttttgacg aggtgactgc ttcgctggat ccagaaatgg tgcgtgaggt gctggaactt
    21961 atcaatgatt tggcccaaga aggccgtacc atgattttag taacccacga aatgcagttt
    22021 gcccaagcca ttgctgaccg gattatcttc ctcgaccaag ggaaaatcgc tgaagaagga
    22081 acagctcaag ccttctttac caatccgcaa accaaacgag cccaggaatt tttaaacgtc
    22141 tttgacttta gccaattcgg ctcatatcta taaaggagat tcttatgaaa ctattcaaac
    22201 cactcttaac tgttttagca cttgcctttg cccttatctt tatcactgct tgtagctcag
    22261 gtggaaacgc tggttcatcc tctggaaaaa caactgccaa agctcgcact atcgatgaaa
    22321 tcaaaaaaaa agcggtgaac tgcgaatcgc cgtgtttgga gataaaaaac cgtttggcta
    22381 cgttgacaat gatggttctt accaaggcta cgatattgaa ctagggaacc aactagctca
    22441 agaccttggt gtcaaggtta aatacatttc agtcgatgct gccaaccgtg cggaatactt
    22501 gatttcaaac aaggtagata ttactcttgc taactttaca gtaactgacg aacgtaagaa
    22561 acaagttgat tttgcccttc catatatgaa agtttctctg ggtgtcgtat cacctaagac
    22621 tggtctcatt acagacgtca aacaacttga aggtaaaacc ttaattgtca caaaaggaac
    22681 gactgctgag acttattttg aaaagaatca tccagaaatc aaactccaaa aatacgacca
    22741 atacagtgac tcttaccaag ctcttcttga cggacgtgga gatgcctttt caactgacaa
    22801 tacggaagtt ctagcttggg cgcttgaaaa taaaggattt gaagtaggaa ttacttccct
    22861 cggtgatccc gataccattg cggcagcagt tcaaaaaggc aaccaagaat tgctagactt
    22921 catcaataaa gatattgaaa aattagcaag gaaaacttct tccacaaggc ctatgaaaaa
    22981 acacttcacc caacctacgg tgacgctgct aaagcagatg acctggttgt tgaaggtggt
    23041 cattaactct taaaagggac tggattttaa gctccaatcc ctttttaaga ttttacctat
    23101 aacatcctga gtctatctaa gatgttcaat ctgaacacag tgtacatact ttatcttcta
    23161 ttgcatatac tttatcacat aagatacgaa tatcctcttc actatgacta gcaatcaaaa
    23221 ttgttgtccc tttttcacta gagagctttc taaacaatgt tctcatattt tctacacttg
    23281 atttatccaa ggcattcata ggttcatcta gtaaaagaat agagggattc tccatgattg
    23341 cttgagcaat ccctagcttt ttcctcatac ctagcgaata agttttaact ttctggtctt
    23401 tttgctcata tagaccaact attttcagtg tatcattgat ttcctgatta ccaactactc
    23461 ctcgtatgct tgccaaatat tgtaaattct taaagccact ataataattt ataaaaccag
    23521 gttcttcaat caaagctccc aaattagctg gaatttttct ctcaggaaca atattttccc
    23581 cattgattaa cacttctcca taagacggac tatataaacc agctattaat ttaaacaata
    23641 cacttttccc tgagccattc gcaccagtaa ttcctataat ttccccctgt ttacaactaa
    23701 agttaaggtt ttgaaaaaca catgtctttt ttaatttcaa ctcaatattt tttaatataa
    23761 ttatttcatt cattctataa acctcctctt ttgacgagtg aaatagaaaa tgctttgaaa
    23821 aagaaagact aaaaatagca actgaagaaa caaatctccc cctacatccc cattccctcg
    23881 attcaaaata taaaatagat aattagttcg atttcctaca aatagaccac caaacacaat
    23941 catgagtaaa aagaaactaa cgcaagcaaa gttcatttgt acattcgctc ctagtgcgta
    24001 taacataaag caaaacaaga ctaacacaca agcattcaaa gaatcaacta taaacaaaac
    24061 tcctatatcc cagtttggta actgtaacat aaattgaatc actagaactt ttaccatgat
    24121 taaaatgagt ccataaagaa aacaggtcca aatctgatac ctaatccaga gcttaataga
    24181 agaaaatcga atcacttcca taaagaaatc ggatgctctt ctacgatata caactgctag
    24241 aaaaaatgta tgaataataa accaatgaag caaccatata gataagacta aaaaagagtt
    24301 ttgactcaga ttaggccctt ttaaaatttc tataacaagt ctatcatttc cttctaacca
    24361 ataccataat cctaaacaaa tcaatatcca aaaaagaaca taaccccaaa agtacttggt
    24421 atagattatc ttattcaacc tccacatgtg actacttaac tttcccattt ccaactttta
    24481 cactctcctc cagtttctat gaacagaaaa tacagtcaat ggaattatga tagatagtaa
    24541 tgtaagccaa taaatcaatg catacggatt ggaatttacc atatactgaa aaattggcaa
    24601 taatccaatt atcccattgt tcaactgata aatccagaat aaggattcta caaataaaaa
    24661 agtaaacaga aatactaagc tcatgtttga ttttttaaac caagaaaaac tgctaatagt
    24721 aagtaaggat aaaaagaaat agtatgctat ataagagaaa aaaaatccta taaagaaact
    24781 agcattgttt gcaatactta taccataaaa ttctcttaaa aaatcaacct cctttatctc
    24841 caaagagaag ctaaaaccat tactaaatgc aattagaaaa atcaataaaa ataaagtcgc
    24901 cgtccaaatc cccgtactaa gagctgctaa tttgaaacta aaactggtaa agtgcttaat
    24961 tgatttcaga cgaatgcgac actccaacct attaaaatag ttattcatca aataaaaaaa
    25021 gaacaatata tatgtgaacg gaaagcaata tactccagtc gtcatatctt gaagtaaaac
    25081 taaaatccat tctaatacat ttggatggat tgaatattgg cgacagcgca ataaatatac
    25141 tgtactagat aaaacacagg atagcagtaa tataaaataa accaatactg ataaaaaatc
    25201 ttttttgtaa aattgaacaa attgtttcat tatacatagt cctctgaatg tagaaaaaat
    25261 gtaccataaa caaccaaaca actaacaaat aaaataaaag caagatgccc actaactaag
    25321 gaaagactga tatctttctg atatcccaaa gctaatgttg tcacaggttc taagtaagat
    25381 agccctaaaa tagcccaaaa aataccacca accatcatat aggcaactgg gatgaaaata
    25441 gctcctattt ttttcttcac tagcaaagca ctagctagtc caaaaataga gaacacagcg
    25501 ccccaaactc cataccagag agtcgtcaca agactataga gcaactgatt agaatcaaat
    25561 aattctttta aggcaccact ataatctcca atataaattt cctgataagg agtcactaaa
    25621 agattaattc ctaataataa taaatagggg agaaaaaaga ctagaaaaga agaaataatt
    25681 gcagtactac ctacaatagc cagatacttc tttttagaaa ttcggcacaa ttgtgctgtt
    25741 agaaaatgac tctcagcatc ctctattatc tgactagaat agggcagtgt acagataagt
    25801 gcagctacta ggctaatcgg tgaaaatcct cgaatagaag aagcggcaaa aaaaatcgat
    25861 aaaccttcaa ttttataaat accattgaaa gcaaggaaat ttcctaaact catgcaaaga
    25921 agggtcaaaa ataaagacat ataaaatcga ggtgattgaa cgactcgtac aagattacaa
    25981 atgaaaaatt ccatccttac tcctccttat aataaaaata gggtgtagca ttcttttttc
    26041 atgctacacc cacaatcaac catctttaag gcttactctg acaagtaagt taataagaat
    26101 ctggactcca agaacctgaa gtatgaattc ttacatgatt tccaaattgt ggcgccatag
    26161 ctaatctagt accagaacca atataattgt caccacctcc attatagtac atgacaatcc
    26221 tagagccaga ccccaatgaa tataccgggg taatatctga cccactatag gcgctacgaa
    26281 tagaggtatt taacctttta ccgccaccag tgctgtcact attattaatt ccagcagagg
    26341 cgttttcttt ctcaagctca ctagttgtat ccgaacccca acgcggcaac gttaaatcat
    26401 aatttccaat ctgtctagct aaaactgtag ggagaaacaa actagatgca attgtaacta
    26461 cgcaaaaaag gaatatattt ttcttctttt catgacatcg tcctcttaag aagtgataaa
    26521 caagatagtt gattgatcaa tttgatacat attacatttt cattatatca ataaaagaaa
    26581 gcgttgtcaa ttattttatt taaaatattg tcatatttta aataaaatgg taaaagagac
    26641 tcggtagcct cgtctctctt tatcttactg acctaacctt cttgccaatt ttcttggtct
    26701 tctttaaagc gttttagaag atcaaggccc tctggcgtga tgtaaccttc ttcttgggct
    26761 agatggataa gctctctata gtttgaaagc gtcacaagtt taacaccagc atctgcaaag
    26821 ttcttatctg cttttggcaa ttggtagctg aaaatcgcta caactccaag tacatctgct
    26881 ccttctcgct tggctgctgc tacagcttca agaactgaac cacccgttga aataaggtct
    26941 tcaaccacta ccattttttg accttgagct acgcgacctt cgatttgatt accagctccg
    27001 tggtcttttg gtttgctacg gatgtaggca aaaggcaagt ccatcttatc agcaataatg
    27061 gctccgtgtg gaatccctgc tgttgcagtt cctgcaatca cttctacttc aggaaaggct
    27121 tctttaatag cttccacaaa accattttca attagggtac gagtttctgg ataggctagt
    27181 gtcacacgat tatcagtgta aatcggtgac ttgataccag atgcccaagt gaagggttcc
    27241 tctggtttga ggtaaacggc ttggattttc aagaggtggc tagcgatatc tttagcaagt
    27301 gtcatggtat tctcctttta tttttctaat ctagttcttt aattccagtt ctgtgtccat
    27361 tcatccttga tggcatgata agctgcaaca ggatcctcag cttgggtaat gggacgtccc
    27421 actacgatat agtcactgcc gatttgatag gcatcagcag gtgtcatgac tcgtttttga
    27481 tctccaactg caacaccagc tggacgaatc cctggtgtca gacagataaa atctggattg
    27541 gtagcctgct tgatgacttg tacttcctga gccgagcaaa caacaccatc caagccagct
    27601 tcagctgtct tcttggcata gtgaatcaca gactcttgca gactggtttg gatattttga
    27661 aactcctgca tctgagcttc tgacgttgat gtgagctgag ttacagcgat caatttggct
    27721 tgactcccaa gaccttcacg cgccgccttc atcatctcta caccaccagc cgcatggaca
    27781 ttagtcatat cgacaccaag ctgagacaag accttcatgg ctgacttgac tgtattagga
    27841 atgtcatgaa gtttgagatc caaaaagaca ctatgaccca aaccttttaa gtaggacaca
    27901 atctcaggcc ccgctgcgta ataaagctcc atccctacct tgagataaag gctttcttct
    27961 gctgggaaaa gagctaaaaa ttccttgacc gcctcaaaac taggaaaatc aagagcaatg
    28021 attggacgat gttctcgcat aggtttctcc ttttaccttt actagtgaga gagtctggcc
    28081 aacagaagcc acgaaaaaag gaacctgcca acagcaaggt tccacgaaaa atgggtagtc
    28141 tccacccttt caccgtctaa ccttagctgc ctctctggac tgctttaaag gttttctatt
    28201 attctattat ttctactagc acttgtcaag taaaaactta gtcacgtatg tgttgactgc
    28261 tattgaacac ctcacaagac tctttccaaa agaatagtta aagactttca cttaggacag
    28321 agaaaaagag tttgcttgtt accctttaat tgaacaaatg ggaattctgt tttattttgc
    28381 ggatgcctat tcatcttggc aaaggggaag taatgagaat gcgaatggac ttcttcgtga
    28441 gtattttctt aaaccgattt ggcaacaatt accgaaaaaa tccttaatgg tgctttgcta
    28501 gcttattaat caccgtcccc aaaaatactt ggattacaag acaggttttg aagcacttat
    28561 agaggaaatt taaaaatgtt gcatttttta ttgcaattta tcagttatct tatcacccaa
    28621 aacttctgca attagtatga gcactattgt tatttttctt ttttcgtaca ctcaaatcaa
    28681 aatatagcaa taagactatt ctgtagaatt gctgtcaaaa agatcagttc atttttcctt
    28741 cccacttgtg tttataatca ttaaaataac tcaattaaga aattttcttt ttcctaatag
    28801 ttatcgtaat taaagttaat agaagaacaa tccaaataag tagtgttaga ttaggaatta
    28861 gagttttatt ccatgaaaat ccctcccatt ttgtgaaaaa cttagtaaac agtcccataa
    28921 aactataatc tgttatcttc gcaactgtct tatccaaacc agatagcatc ggtaagaaag
    28981 caactaaaat catagcagga agactgataa cctgagctac tacttggctc ttcgcggtta
    29041 aacctatcaa taaatagaat aaaatgatgg ataaagaggt tagaagaacg attgtaatat
    29101 aattaaaagt atgtacaatt gtaactccta aaataagagg agtagttccc ataatcacaa
    29161 aagttagcaa aaaaggaaga aacatcgttg ataaaatgta ttcggatcct ttaacaccac
    29221 tcaacagaag agtttgtaaa ttgtactttt ctttttcttc agacaagata atagttatag
    29281 gacttccaac agccaaagcc aaagaaaaag gtaaacacat catcaaaaga actaatgcct
    29341 gttgatcgtt gaccttcccc tgtgtttcca taagatattt ataaaaatat gtgaaagcaa
    29401 aaggcactaa aacttgcaat aaaatactct tattggaaag gataatttga caacgcaacc
    29461 ataccaaagc cagaaaccgt ttaagcattt agctttcctc ctgttaatgt gataaaaata
    29521 tcttctaaag taggctcaca tgaatgaatt gaaaaaatat tttccagatc agcctgagat
    29581 acctgttcta gtgatgtaaa atcaaaagtt atctgattcc cattataatc tgtaacctta
    29641 atctttttat ctttattata tctttgaatg agttcagaag gagctccttg ctcaactaat
    29701 ttccctttat ttaataaggc aacataatca cataaaagag ttgcttcatt catatcatga
    29761 gtcgttagaa aaatcgttgt ccctgctgtt ttcaattcta aaattaactc atgaattgtt
    29821 cgagaagttg tgggatctag acctgaggtc ggttcatcca gaaagagtac agcgggtttg
    29881 ttgataagag ctcgtgctaa aagcattcgt tgcctcattc cagtggataa ttttcctgct
    29941 accatcttgc gactatcata taatcctact cgctttaaca aattatcaac acgtgattta
    30001 ctaatattat aaaatttact ataaaaaaga agattgttat acagagacat tttctcataa
    30061 aatccacttg tatcgctaac caatccaatt ctctttaatt caccgcttgt taaattttga
    30121 gatttttgtc ccaaaataat agattgtcct ttatcggcaa ggaactgccc agtcagaata
    30181 ttaatcgttg tggtctttcc agaaccagat ggtcctaaaa atctaacctt ctttaacagt
    30241 gaagcttata ttatttaaag ctattttatc accaaaactt tttgataaat ggctaacttc
    30301 aatcatactc attgcacctc ctttatattc tacattttta cttaacatct atttacttat
    30361 ctttatcaaa taaacgtctt aaaaaaaaca ataacattaa gcatataacc gttagcaaga
    30421 ttgtttcaat attattgata atacgataca ttctcaagca gtataaaata attatatata
    30481 tgcaaatgct cattatacct atttttttaa acatactaag cctccttgct aaataataaa
    30541 gttatataat aactaagaca cactatacct aacataataa atatccactg gtaactgaat
    30601 aaatgttcta aaattaacaa gcaaaaataa aatctcaaac gatgaaaaaa gccatactat
    30661 attttccaat gatgtttgaa tatttttatt gtagtaagca taatatatag caaaaataat
    30721 acccaagaac aatactatta attgtgtttc tataacagtg aactgcccaa tagcagataa
    30781 aaaagctact cctcctgata ataagcaaaa acaaactgaa cgaataaatg ttttcgctct
    30841 aatattgtta tctttcactt tattattttt ttacaaattg gacattctcc gttttccaga
    30901 acatattttt cttgacttag agcatgattt ctcatattat aaacgtaagc gttatctatt
    30961 aggatttcat tataacatcc cagaaatatt ttaattatta aattagtcat tatccctccc
    31021 aaaatagcag gcatctctgg tgtagtcggc cactttgtct tatcagataa agtgtactta
    31081 tttatatctt tgtttatatt ccgacaacca aagcaagaac cgatggtagg gatatatatt
    31141 atcagtaata agatagcatc cattaaaccc tcctgatatg taggatatct tatgcgatac
    31201 agcaaattga ttgacaattt ttataatatc aatgggcgta tcaattgctt taacgataaa
    31261 atctatactc ccatattccg caacaatttt ttctaattct tctactgaag aaactttaat
    31321 agaaataggt actacctgaa catctgaatt atacttgtgt attttttcag aaagaacatt
    31381 aatcttctcc ttaccaacat ccgactctgt ataaagaatt tgcctattta aatttgatgg
    31441 ttctattata tcgtaatcag cgacaataag tttcctcact ccatacatac ttagacttag
    31501 agatatataa catcctaagg ctcctgctcc taatactaat actgttttat tctgtatttt
    31561 attatactct tcattataaa ataacgaata gtaaccttta gttctagaat atctactatc
    31621 aatatctatc tcatccgaaa ttaaaatttg ttcatttaat agttcaaatg ttagtttact
    31681 gcctaatact tcttctatct ctaatagttc cttacaacta ttaaatagat cgttgataaa
    31741 ttcttgcgaa atttgaggtt ctatagctat ttcccgcata ctccgaccac gcaaatacat
    31801 tataccttct tttttataag caaaaacata actatttacg tagaacatat ttcgtccttc
    31861 ctctcatata taatatagaa agcagtatag aaacaaccac ccctcctata ctacgaacaa
    31921 taatattagg tgtcaaaaac tgtaatagtt gactcaaagg gaaataaata ataacaaatg
    31981 ctattaaaag ttgaactata tattgaaaat tcaagttatt attgttagaa ttcaagtatc
    32041 ttaaaataat accactatca tactgaaaaa aaggaattga attaataaaa atcataccta
    32101 agttaatgat aaaaaataag agtccaagca atttatacga tgtgaacaat aaaacaagta
    32161 aacctgtaag tgataaaatc gaatttgaag caattcctgc taacataatt ttcaaaaatt
    32221 gttttttatt ttttaagaat tgcaccccac ttaaatctac aaaaaaaagc caaattaaac
    32281 aaaagtagca ttattccaca atttgggatc tcaatttgat aattattagc aattattgca
    32341 tgactaaatt catgtatcgt tgcagacata ataacaacaa gcaaccaaaa taaaagaatg
    32401 tttagcgtta ttggaaagtt ttggaaatta gtcaaaatat ccgccctata aatatacata
    32461 ataaaacatt gcaaaataag agccaatggg aaaataccaa ataggatttt ttcaaaattc
    32521 ttattaaatc ttttatagtt taatttttca gataatgtta tattaaagtc ccaagatatt
    32581 ttaaaaatat ttatcttttt tcgtgatttc atagaatcta taagtcccat tttactaaga
    32641 acaatataaa atcttaaata atatttcttc cctactaaca ctaataagtc cgatatggta
    32701 aattcttgac ctattagttg ctctaaccat ttttttcctg tttcccaact aatacatgtt
    32761 tcttactaga tggtatatat agatgatact gtccctcata aggagtaggt aatatcttaa
    32821 tcttatcaac aattctcata acaaacctaa cctttaataa ataaaagagg ggctaagtaa
    32881 aacatactct agtccctcag tccgcaatca ataaaataat gactaattct attaatctct
    32941 tgctgcaaga ctaatacgga aaattcaaat gactgtctaa aatgaaattg aaaaagcttg
    33001 atgttagtaa atgaacaaac ttcaacaacc agcaagagca aggattgcta aaccaaatcc
    33061 gatacctgtt gcaagtccag ctgaaaaatc actaactggt actgaaattt cttcaatttc
    33121 ctcaaataaa aagttatctt gcatgattat cactccctat ctttttaaca acaggctatt
    33181 ccaattaaga gaactacccc agttccaagt aaaactcccc caaaaattca ccatctgtag
    33241 gggctacgat ttcttcaatt tcttcaaata agaatgcttc atctgacata tgtgttacct
    33301 tcttcataaa aaattatttt gtaatcgatt acattgcaaa tgtaacataa agaaaaacag
    33361 atgtcaaata ttaaacgtaa gaacatggtc actaaagaac tataagagaa aaggtaaacc
    33421 tagcgacgcg atgagcgctg ggtcgtttga tttcgattgc tctcttcctc ttgttttttc
    33481 tgttcttctt cctgtttttt ctcggcttcc ttggcctctt gtttggcttt ttcctcagcc
    33541 tccataatta atttatccgc cacagtgtaa ctgtaaattc cagcttccat gtcgaccaca
    33601 ctcggttctg acaattgtgg cttaatctta ctgtaatatg gcagtttctt actcatttca
    33661 gatagaggaa ccaagacttc gtccgaatca ttcatggtca atcgaattaa atcggatgtc
    33721 accttgcttg gggctaattc caccttttgg atagccgcct tgagttctgg gctaatttga
    33781 gcaagttctg agacaaaaac cttgatttgt tcactatcat taaagagaac tgataaataa
    33841 gtttctggta aactgttcag actcacagaa ctagtctcaa gctgaccact ggaaagaata
    33901 ggataatgat tttcaccaga aatatagtag gccacaatat catattcctt gaccttaata
    33961 gtgaacttag ttggaaattg atagacaagt tgagctgatt caacccaata gttagactta
    34021 atctgctttt catattttgc cttgtctagc agaaggttaa tcgtataatc cgaatcctga
    34081 atgcctgaag cctgtcgaat atcatcagct gtagtttgca ccgttccctc aacacgaata
    34141 tctttcatgg tcgcataagg actgagcaag taggcagaga caatcaataa aagcagactt
    34201 ggaaataaaa tcgtgaaggc tcgcaagata tggataccag gaatctttgc tttggctggt
    34261 ttttcctttg tagccttttt agaaagcttt ttatcctgtt cctccttctc tttagactct
    34321 ggttcttctt tctcttcttt ctctttgtca gcctctgagg atgctacttt ttcttcagac
    34381 tcttccttag ctgattctga atcttcctgg tctgtttcac tctcctggtc ctgtttgtcc
    34441 tctgacttct cagattcttc tcccattcga gcttgtcttt ccttttcctt ctcctcagct
    34501 agagccgcct cttcttcagc cttctttttt agatattctt ggtttcgttt ctgccattct
    34561 gataactctt tcaattcttc gaggatttct ttgtcctcat ttttcttatc ttttgacatt
    34621 tactttcctt atgataaatc ttttttcaac aattgataaa aatctgctag agatttcaat
    34681 tccttagaag ccttcatctt agcttggtaa tcttccttgt gacttagtaa gtgagaaagc
    34741 ttctcttcca aactatccaa ggtcaaatcg ctttcttgaa ggtcttctgc atagcctttt
    34801 tttacaaagt aagctgcatt ttcaagctgg tcaccacgac tagcttcacg accaagcggc
    34861 acaatgacat gcaattttgc tatcgccaag agctcaaaaa tcgtattggc accacctcgt
    34921 gtcacaacaa tatcagccaa ttccatcaag ggttgataga gatcggtcac atagtcaaca
    34981 cgaaaaagat tttggctcaa ctcattcagg ctagaatctc cagttagatt gataatattg
    35041 tagcgctctg ttagttcttt cttatggtct gtcaccaatt ggttaaagac acgagcacct
    35101 gcagaaccgc caacaaacaa tacagtcggc aatttatgat taaagtggct ttgaatatcc
    35161 accaattcat ctggttctgg atttttttga tctgaaacct tggccactgc tcccacatgc
    35221 tcaaccttag acaaactcga agcttgctca aaggttgaat acatcttagt cgcaaattta
    35281 taggcgattt tattggccaa gcccatagac aggtcagatt cgtgaataaa gacaggcact
    35341 cctgacacac gcgcagcgat aacaggcggt actgagacaa agcccccctt tgaaaaaagg
    35401 gtctgtggac gaagtcgcaa catgataaag agcgattgga cgattcccca gcaaactttg
    35461 aagacgtcca gcatattttg ccaagagaaa tagcgacgca attttccagt cgcaatagaa
    35521 tggaaggtga catccaaacc tgacttaagg atttcttggt gttcgatacc acgcttgtcc
    35581 ccgatatagt ggacttccca accatcttcg atgaacttgg gcattaacaa aagattgagg
    35641 gtaacgtgtc caaccgtccc cccacctgta aagacaattt ttttcatatt attcttttaa
    35701 ctccgctact gtgtcgataa agaggtcgcc acgtacttca aagttagcat acatatccca
    35761 gctggcattg gcaggactaa gaagaaccac atctccttga gtcgcaagct cataggcctt
    35821 gcgggtcgca tctgcaatat ctgtcgcctc cacataagcg acaccagcct tgtctgctgc
    35881 ccgtttgaca cgttctgcag attgacccag gatgaccatc ttcttgagtc cagtaatgtc
    35941 tggcaccaat tcgtcaaact cattgccacg gtccaaacca cctgcaatca agacgacctt
    36001 gctgttatca aatcctgaca aggctttttg agtagccaag atattagttg atttactgtc
    36061 gttatagaat ttaacaccct tgatgtcatc cacaaactgg agacggtgtt tgacaccacc
    36121 gaaggctgaa agagtttcct tgatggtttg attgtccaca ccacgaagct tggctacagc
    36181 aatagtcgca agggcatttt ccacattgtg gctacctgga acaccgattt cattcgctgc
    36241 catgactact tcaccacgga agtagagttg accatcttcc agataagctc catcaacctt
    36301 ttcaagtgtt gaaaatggta caacagtggc ttctgtcttg gaagtcaagt cttttgccaa
    36361 gtcttgatta aagttcaaga caaggaaatc agctgctgtc atcttgttct ggatattcca
    36421 cttggctgct acatattccg aaaatgaccc atggtagtcg atatgagttg gcatgaggtt
    36481 ggtaataacc gcaatctctg gatggaattc ttgaacaccc atgagttgga aagaagaaag
    36541 ttccataaca agcgtgtcct tatctgatgc tatttgagca acctgactag ctggatagcc
    36601 gatattccct gataaaagac catgttgccc agcagcagtc aaaacttccc caatcatagt
    36661 cgttgtggtt gtcttaccgt tcgatcctgt gataccaata atcggtgctt ctgaaatcaa
    36721 ataagccaat tccacctcag tcaagactgg aattcccttg gccaaagcct tttcaatcat
    36781 gggattgttg taggggatac ctggattttt caccataagg gcaaactctt catccaagag
    36841 ttccaaagga tggccacctg taatgacctt gatcccttct tccagcaaac tttgggcagc
    36901 tggattgtcc tcgaaaggtt tcccatcatt tactgtcaca atggcaccta gcttgtccaa
    36961 caaacgagct gcagattcac cagacttggc caaacctaaa acaaggactt tcttattttt
    37021 aaattgatct attactttca tgtctcgaac tccatttcta ctcctactat tttaccattt
    37081 ttatggaaat aaaaaagcca caaagtgtgt ttgtgactct ttcttctaac tgaatcttac
    37141 catatcatct atgtgataaa tcggtaactc gaatgacctg atccacttgt tcccaaataa
    37201 gaggattgtg ggtcgcaata ataatggtcc gattcggatt ttttaaagat tctaggatgg
    37261 aaagtaattc ctcagagttt ttggggtcta aggaagtggt tggttcatct gcgaggatca
    37321 aaggtggatc ctttaaaatt atcttcgcta atgcaacacg ttgtgcttct cctcctgata
    37381 actcaaatat aggttgcttc aaatccaaat aagagaggtt tacacagttt agagcttgtt
    37441 tcatcaaaga gattttctct ttttccttca actttttacc aactaaaccc agattgagat
    37501 tctctttgac ggtttggctt tcaattaagc caaaatcttg aaataagtat cccaagtaat
    37561 ctctaaagaa aacagaaggc ttgatgtcct taagagaagt accatcatag atgatttgtc
    37621 ctttgtcata tggctctaat cgtccaatca tattcaagaa tgttgtctta ccacagccac
    37681 ttgtaccgat taaggcataa attttcccac cttcaaaatg aagatttgta tctgaaaata
    37741 gctgacggct tccaaatttt ttagatatat tctttagttc aatcatccta ttttcctttc
    37801 ataattgtca tagaaacacg agattctttc tgcgcttgac ggtaaagcgt cagaactgca
    37861 ctagctagaa agactaataa agtgagcaag ccaatcacca agtctcgact gcttaaaata
    37921 aagagactag caccaaatac aaaactggca aattgactaa ccatatactg agcatgtgtt
    37981 tcaaaaaatc gtaaacctga aattcgttta atcaaaatat ctcggcggaa ttgctcgaaa
    38041 tatagaagat tgacagaata aaatagtaat aaggaactag ctatccccac aatagctcct
    38101 aagattaaag ttgctgtttc agtttgaact tcattataac gagttagata aacacttctt
    38161 ccttctttaa gataggatac ttgctcataa attccagctt tcttcaagag ttctagccca
    38221 ctctcatatc ctttgataaa gagttgtttt ccagcattga tagaccaact agataaggat
    38281 ataaaactat cacctgtaga agtcggcgtg aataccacta aaatcggatc agtcaaatac
    38341 tgagtagata cgggattctc accgttatta taaacaaacc gcttttctcc cattgaaaga
    38401 taactaacgt gcgctttcat ctcataatcc aaaggagcac ttgcctcctc accagatttt
    38461 ccataataac tcaatctttc ttcaaaaact ttcttaagtt ctgcttctcg agagcgcaaa
    38521 tgttctggga gcaagaggat aaactcacct ttttggagat gggctaactt ctgtttggtc
    38581 tcagcatcta ccacgacctt ttccttgtcc aaataactgg gactaacata gagcgtatta
    38641 gcatctggac tataggtatc cagtgtctct ccctgttcat tttttccttg tggattggca
    38701 aaatggagca gattatcctt tacataaaga gcttgttctt cttcgattgc ttccttggca
    38761 aaggcatacc acttgctctg attttctgta tcttttcctc tatcacctaa gccaaaagaa
    38821 atttgataat agtctgctct atcctgccat gcttgttttg aaatttcaag ttctttcaat
    38881 cgttggtaag acatcaaacc tgtcttaaca gcgtagccta ctgtaaagac agcaaccaac
    38941 tgacacaata gggttaaaat catcaggcgt ttaaggggta atctcccctt aataacggga
    39001 actaatgctt tgtaactcaa actcattaga taaagaagca ttagtaaaat tgaaatcgcc
    39061 aataaaaaca acagatagaa actaatccca aaaccatagg tggctaacaa gataggataa
    39121 aacaaacctt gactaaaaag aacgactccc ccacctagga aggaaaggag ggctgataga
    39181 aggagccatt tgatatcagt agataaagaa tgccccatga tggataagag agtctgacca
    39241 gaaaagagtt ttatacctgc tgctctcatt tccttaatcc gagtgataat cactaaagca
    39301 aagaaagata agccaaatat tgctaaacta attaaaataa ggggatttag taatattcga
    39361 aaagcaagaa aatagggcgg tatctttcgg tcagcacttg ctttataacc caaatctcct
    39421 aatttatcgg caagcttttc tttcgtcaag gagcctgaca aaaggagata actatttagc
    39481 ggatcactac gttcacgact ttcttggcta gcttcttgga attcttttgg taaagttccc
    39541 tgaccataag ttgcataagt aaagtgagtc gtcccatcct tactcggctc tacaattctt
    39601 ctagctatta aactctgttc tgagtttgca aaattctcca attcctgttc aaatacctca
    39661 cgcgtcggtt cctgagtatc ttttttgaca cgaagtaaag aaacggaatc atagcttgca
    39721 tataaatatt gtggcgcacg taagacaata atccaagcaa ggaagaagct gagaaaaaaa
    39781 gttgataata atatgaatag tttcttcata gtagactcct tgtaaacaaa attccccctg
    39841 taatttctta caaggggaac gatttaaatc aatgaacgat tagtcataat cacagtaaaa
    39901 tgctacttgt tctccccatt tagtccaaat ccatgcatag gaggtttttc cagcagaagc
    39961 ttctccttta tctgaatgac tattccatct acttacaaga gaagaataat gatatttttt
    40021 accatgatag taatttgaaa aagcccaacc acctcctgaa ccttctccat acgtccatac
    40081 tcctccatct ggatattgta cagcagctga tgcagctccc aataatgtaa aacttgaaat
    40141 aagagctaga gcaagtaatc tatgtttttt cgttttcatt ttattttttc tttcaaaaaa
    40201 agcacacctt gagcaacaat gcaacaaaat aaaccctcct ctctcttttg ttgaaaccgc
    40261 tttcttatgt gataaaaata tcatttttat tatttgttgt caaggaaaaa atcgaatttt
    40321 ttagatattt tactacattg cctctatgaa taatattata tagtagtttt attttaaaat
    40381 aatatgcaac cagtactaac caaatataaa atagatgcca ttaacgaatt ttattcaagt
    40441 ttttcccatt catactatcc aagcaaaaga gatgatgtta tagtacaaaa caattcaaac
    40501 tattgtaaaa ttcctagcaa aaaagagagc caaaactctc ttttttatct tcttttactt
    40561 tttttgactg gcatgagtgt aatgtctcta acactaaagt aagctaggat caacatggct
    40621 attgctagga atatttctgt tggtaattga aaaattttca gaaaagatag aaccaataaa
    40681 atcaagagtg ccactaaaat acataccata gcgacgatat tgactgtccc tttaatgctt
    40741 tctggtgtcg caaatacata gagtaggagc agtaaaattc ctaggactaa atagaccatc
    40801 tttctctctt tctagctctt attcagctga ttttttcttc ttgttagctt tctcacgctc
    40861 tgctttgtta aggatttgtt tacgcaaacg gatagactca ggcgttactt ccatgtactc
    40921 atcgtcgttc aagaactcaa gagactcttc aagtgtcaag atacgaggcg tcttgataac
    40981 agctgtttgg tccttagtag ctgaacgaac gttggtcatt tgttttgcct tcgtgatgtt
    41041 aactgtcaag tcattttcac gagagttttc accgatgatc attccttcat aaacctcagt
    41101 acctgggttg acaaagatcg taccacgttc ttcgatagac atgattgagt aagttgtagc
    41161 cttaccagca tcgatagaaa caagggcacc acggtgacgt ccaccaattt cccctggaat
    41221 caatggcaag tattggtcga aggtatggtt catgataccg taaccacgag tcattgacaa
    41281 gaactcagtt gagtatccaa tcaaaccacg cgctggaaca aggaagacca aacgagtttg
    41341 accattacca gttgaaatca tatccaacat ttcaccttta cgttcagaaa ggctttggat
    41401 aacagaccct tggtattctt ctggagtgtc gatttgtaca cgttcaaatg gttcacattt
    41461 aacaccgtcg atttctttta cgataacttc tggacgagat acttgaagtt catagccctc
    41521 acgacgcatt gtttcgataa ggattgacaa gtgcaattct ccacgtcctg aaacagtcca
    41581 tttatctggt gaatcagttg ggtcaacacg aagggaaacg tctgtttgca attctgcctg
    41641 caagcgttct tccaccttac gagaagttac ccatttacct tctttaccag caaatggtga
    41701 gttgttgacc aagaaagtca tttgaagagt tggctcatcg atgtgtagga ttggaagagc
    41761 ttctactgca tctgtcggag tgatggtttc accgacaaag atgtcttcca tacctgaaac
    41821 ggcaatcaag tcacccgctt tggcttcttg gatttcacga cgttccaaac caaagaaacc
    41881 gaagagtttt gtaacacgga agtttttagt tgtaccgtca agtttagaaa gggtaacttg
    41941 gtccccaacc ttaactgtac cacggaagac acgaccgata ccgatacgtc caacgaagtc
    42001 attgtagtcc aaaagtgaca cttggaactg caaaggctca tctgagttat ctactggagc
    42061 tgggatatgg tcgataatcg tgtcaaagat tggtgccata gtcgcttctt ggtcagctgg
    42121 atcatctgac aatgaagaag ttccgttgat cgctgaagca taaaccactg ggaaatcaag
    42181 ctggtcgtca tctgcaccaa gctcgatgaa aagttccaag acttcatcca ctacttctgc
    42241 tggacgagct gatggcttat cgattttgtt aacaaccacg attgggacaa ggtcttgttc
    42301 caaggctttt ttcaatacga aacgagtttg tggcatggtt ccttcatagg catctacgac
    42361 caagacaaca ccgtcaacca ttttcatgat acgctcaact tctccaccaa agtccgcgtg
    42421 tcctggtgtg tccataatgt tgatacgagt tccgttgtaa gcaacggcag tatttttagc
    42481 aaggatggta atcccacgct ctttttcgat atcgtttgag tccatagcac gctctgccaa
    42541 ttcagtacgt gcatcaagcg tttctgattg tttcaataat tcgtcaacca gggttgtttt
    42601 accgtggtca acgtgggcga taatcgcaat gttacggata tcttctctta attttgtcat
    42661 gatttcctct ataatattca aaatttattt tctaactgaa cgattatacc ataatttcaa
    42721 ataaataaca taactcaagc aagtgtaaat gttttcactc cgcttttctt ttcacgtcaa
    42781 gccttttcaa agcaagcgac ttatgataag ataggcacag tatgcgttta gataatttat
    42841 tagcccaaga aaaagttagc cgaaaggcca tgaagcaagc actcctcaga ggggaaattc
    42901 tagtcgatgg ttgcccagcc cgatccctag ctcaaaatat cgatacagga ctacaagaac
    42961 tcctttttca ggatcgaatc attcaaggct atgaacacac ctatcttatg cttcataagc
    43021 ctgctggtgt cgttacagcc aacaaagaca aggaacttcc gaccgtcatg gacctgcttc
    43081 catctgacat ccagtctgac aagctctatg ccgttggccg actggaccga gatacaacgg
    43141 gactcctcct cttgaccgat aacggtccct tgggctttca gctcctccat ccccaatatc
    43201 atgtcgataa gacttaccaa gtccaggtta atgaacttct aacacctgac catatccaag
    43261 cctttcaaaa gggaattgtc tttttagatg gtactgtctg taaacccgca aaactagaga
    43321 ttctatctgc aagtccctcc ctcagtcaag cctctatcac catttcagaa ggaaaatttc
    43381 atcaaatcaa gaaaatgttc ctctcggttg gtgttaaggt gactagcctc aaaagaatcc
    43441 aatttgggga cttcacattg aacccagatt tagcagaaag taactaccgc cctttgaacc
    43501 aaaaagagtt acaaatcatt aaaaactatt tagagatgag tcgataaaac aaaaaaagct
    43561 ttaaaactaa agcttttttc ttttatttac cgaaaaatta aggcgattgc tacaatccag
    43621 ttaactacag aaatcacaat tcctaagata ttaagaatct tttctatttt atagtctaat
    43681 tgtgactctt tttggtatga aatagccaag accaatccta tgatacccaa aatcaagcct
    43741 acaattggaa ataacaaacc aagaataatc gacaagatac ccacaaaaag tggatttttc
    43801 ttcttttctt tcatgttcta agaactcttt aaattttata caaattaatt atactataaa
    43861 acaatagctt catcctatca ttcgactaat ttggaaataa ggttagctag tcttcacttt
    43921 ccctttccaa gaatccaagc cataagaaag gatataaatc tcagaaaaac cttgtttttt
    43981 caagtaaaga gctgcatttg taactcgttg cgcacgttgg ttctcgtaga gaaggacagg
    44041 tttatcttta cgaagggctg caagactagt tttcaactga cttgaaggaa tattgcgtgc
    44101 accaaggata tgttttctgt ggaattctgc tgggtcgcgc aaatcaatca attgacccgt
    44161 acgaatcaag gcttcaaact cctcattgtc cacaatttta gccgcacgac gaatacgaag
    44221 atagttaaag cccatccacg ccaacattgc tagtataagt gcccacaaaa tccaagtaac
    44281 cattagttct tttctccatt tttctcaata taatccaatt ctaccttgtg ctctctgcga
    44341 agaactgctt ctgcctctag atagtctaat ttatccatca accctgcatc gtaaatccga
    44401 gatagttcca acttcatcag ttcaatatca tataagcgtt ttcccatgta aacaataata
    44461 ccaaatcgtt tgaggaattg ctgcacatca tagaatgttt tcataagact cattctagca
    44521 aaattttgtg tttttttcaa gaagagactc acacaatgct ccttattttc ctatcttctt
    44581 tggcgattct aaggcaagtg tggtacaata aaaacatgag aattcaacaa ttacattata
    44641 ttatcaaaat cgtcgaaact ggctctatga atgaggcagc caagcaactc tttatcactc
    44701 agccaagtct ttccaatgct gtgagagatt tggaaaatga aatgggcatt gagatcttta
    44761 tccgcaatcc caagggaatc accttgaccc gtgatgggat ggagtttctc tcttatgccc
    44821 gtcaggttgt cgagcaaact cagcttctgg aggaacgcta taaaaatcct gtcgcccacc
    44881 gcgaactctt tagcgtttcg tctcaacact atgcctttgt ggtcaatgcc tttgtctctt
    44941 tgctcaagaa aagcgatatg gagaaatacg agcttttcct tcgtgaaact cggacttggg
    45001 agattatcga cgacgtcaag aacttccgca gtgaggtcgg ggtcctcttc ttaaacagtt
    45061 acaaccgtga tgttttaacc aagatgctgg atgacaatca cctactagcc caccatctct
    45121 tcacagcgca accgcatatc tttgtcagca agaccaaccc tctggcaaag aaagacaagg
    45181 tgaaactgtc tgatttggag aatttccctt acctcagcta tgaccaaggg acgcacaact
    45241 ccttctactt ttcagaagag attctttctc aagaacacca caagaaatcc attgtggtca
    45301 gtgaccgtgc caccctcttt aatctcttga ttggtttgga tggttatacc attgcgacag
    45361 ggattttgaa cagcaaccta aacggagaca atatcgtttc tatcccactg gatattgatg
    45421 acccgattga gctggtctat atccagcatg agaaaaccag cctatctaag atgggcgaac
    45481 gctttatcga ctatctacta gaagaagttc agtttgatag ttgagaaatg ataagaacca
    45541 atatgtaggc tagcaacaac ctgcacattg gttcttttta cttataatta aaagtttccc
    45601 ctgccaactt atcagctagc ttgggaaaga gagtataaaa cttatgggct aggttcaaca
    45661 aaatcgggag attgagttct cgtttatttt ttcctataat cttgacaatc tttttagcca
    45721 ctgcatctgc ctctaagagg aagcggtcaa ccgatttaag ataagttcca tctgggtcag
    45781 cttggtcaaa aaatcctgtt cggattggac ctggattgac tgttgtcaca tagactccat
    45841 agggcataag ttcgagtcgc agagcatttg aaaaaccaat agccgcaaac ttggtcgctg
    45901 agtaaagact agacttgcca gtagctatta gacctgccat gctgacgatg ttgatgatat
    45961 gccctttgct gctttccttc atacgagccg caaggtgacg agacagattc atcagggcaa
    46021 aggtattgac ctcaaacatc tggtgaatat ctttatcagc aatctggtca aatccctcaa
    46081 aaatcccgta accagcgttg ttaatcaaga catcaatctt gccatagcgg agataaagat
    46141 cagttaccag agcttctagg gctgaatcgt cggtaatatc aatttcaatc aattctgcat
    46201 gggaataatt tccgtagagt tgggctaatt tttccttatt tctaccaagc aagatgagtt
    46261 ggtcattggg caggagtttg accatttctt gagctagacc accgctagct ccggtaatga
    46321 gaatagtagg catacttatc ctttctgtga ctgctagatt tccacttctt ccaagtcttt
    46381 gaccacatgg acattttcaa aaattgtggc agcgtccttc ttgagtttgc ttatatcttt
    46441 tgagaggaaa cgggcactga tatggttgag taggaggcgt ttggcacctg cttctaccgc
    46501 tacttgtgca gcttgcatat tagttgagtg accatggtta cgagcaattt tttcatcacc
    46561 cttgccataa gtggactcat gaactaggac atctgcattg acagccagac gcacactggc
    46621 atccgttttt cgagtgtctc ctaaaatagt gataatctta cctggacgtg gcgctgagat
    46681 atagtctgct gccttgattt cagttccgtc ttccaaaaca agatcctggc cgtttttgat
    46741 tttaccaaaa agcgggccga acggaacacc agcagccttg agtttttcag catccagcgt
    46801 cccttctaga tccttttgca tgacacgata gccaacacag aaaatagtgt ggtccagctc
    46861 ctctgcatac acagtgaatt tatcggtttc aagaatttta cccagagaat cttggtcaaa
    46921 ctcatggaaa tgaatgcggt agggcagacg agaacctgac acacgaaggc tggttaagac
    46981 aaatgacttg attccttgag gtccgtagat ttccaaatct gtctgctctt cattggcctg
    47041 aaaggcacgg ctagaaagga aacctggcaa accaaaaatg tggtctccat gcagatgagt
    47101 aataaagatt ttgctgacct tacgtggtcg aattgtggtt tccagaatgc gattttgcgt
    47161 accttctcca cagtcaaaga gccaaacttc gttaatctcg tccaaaagtt tcagggcgag
    47221 acttgaaacg ttgcgggctt tagagggctg accagccccc gttcctaaaa attgaatatc
    47281 cattcgatac tttctaatta atcaatatat aacatggctg tgcggttttc cgatcggaaa
    47341 tagcgtttgc cagaaaaagc agcagcttct tgcaataaat cctcttggct gtagcctttg
    47401 agacgttttc gaccatcagc caatctttcc aaatcagtca aagctgtgag actttctagg
    47461 ctgacaactt cctcgtcctt gacaggcttc atgtaaatct taccagactc ttcaaagact
    47521 aattgatggg agaaaatttg cgcaatttca aagagcaagt catccgagat tttctcctca
    47581 ttttcagaga aaatccgacc aaagccgtca ctctcataac aaaaaccaaa ggatttacca
    47641 gacagattaa gccgaataaa aggcttattt tctagggtga aacttggctc agtattgtaa
    47701 agattcagtt cctgactgag ttctgcaaaa taatccgtcg cagcctgagg actttttttc
    47761 tgatagagtt ctgcaaagta ggcattaaca acacttggcg gaggtgtaat aagtgttaac
    47821 tgctcctgct ctgttttacc agctagaagc tgatccagat agaccttgtc cagacttgta
    47881 taacctccat actttagagc caaagtttta atatcagtca taaaattctt ctaacctcca
    47941 tttatttttc tcggaaatgt agcctgtaat cacttcgccg tcttcctgat aatcacgttc
    48001 ttccagaatt gcaacactct ctaaatcatg aatcttgtag gactttgaaa aaggcactcg
    48061 cagggtaaat gcttcaaaaa tttccttaat cttatctagc aataatgctt gcaagttttc
    48121 acgactgtcc tcagacttgg cagaaatgag ggtatatggc gtttgggtag gcgtgaaatc
    48181 ctccaccaaa tccgctttat tataaagcgt caagtgagga atatcttcca tgtccaggtc
    48241 tttcatgatg gagagaaccg ttttttcatg ctcctcgtgg taaggattgc tagcatcgat
    48301 aacatgaacc agaaggtcca catgcttgct ttcttccaag gttgacttga aactggacac
    48361 caactctgtc ggcaaatctt ggataaagcc aacagtatct gtcaaagtta cttggagatt
    48421 gcctcccaga tgaatactct tggttgtcgc atccagagtc gcaaagagct catctgcttc
    48481 atactgggtc ttactggtca agatgttcat gatagttgat ttcccagcat tagtataacc
    48541 aatcaaacca atcttaaaag tgctagactc caaacgtttt tctctgacag tcgcacgatt
    48601 tttctcaacc accttaagct ggcgctcgat atccgtgatt tgattgcgaa cgctacgacg
    48661 gttcagctcc agttggcttt caccaggacc acgggaacca attccccctg cctgacggct
    48721 gagcataatc ccctgaccaa ccaagcgagg caagaggtat ttgagttggg ctaggtggac
    48781 ttggagcttc ccttcatggc ttcgagcccg catggcaaag atatccaaaa tcaactgcat
    48841 acggtcaatg accttaacac cgagaacttc ctctagattg acattctgcc ttggggtcag
    48901 acggttgttg acgatgacag tagtgatttc ttctgcatcc accataagcg caatctcttc
    48961 caacttacca gagccgacga aggtcttgga atcatatttt tcacgttttt gtctgtagct
    49021 atctacaacg actgcccctg ccgttttcgc taaactagcc aattcttcca tggagaggtc
    49081 aaaactgtcc ataccctgca attccacacc aatcagcagg actcgctcct cttttttctc
    49141 cgtttcaatc atctaaaaac tcctctatct ggcttaaaat gcggtcttgt acaccagatt
    49201 ctccaatctg ataaaaggtg acctgcatgc gattacggaa ccaggtcagc tgacgcttgg
    49261 caaaacgacg ggtcgcctgt ttaagactct cacgagcttc ctccaaggtc tgctctccac
    49321 ggaaataagg aaagagttcc ttatagccaa ttcctttagc agcctgtaca ttaggggaat
    49381 ggtcaaacag ccacttggcc tcatccaaaa gcccagcctc aaacatcaaa tccactcggt
    49441 ggttgatacg ctcataaagt tgactacgtt catcatccaa gcagataatc agcggttcat
    49501 acaaaatctc ttgattttcc aaatcctgac caaaatgggc aatttctaag gcacgcatag
    49561 cacgacgacg attaaactgg ggaatctcaa ggcctgcttg ctccaccaaa tgggctaatt
    49621 cctcatctga atatggctcc aaactagctc gataagctaa aatctcctca tgaggagtct
    49681 ccccacctag gtggtaacct tctagcaagc tctggatata aagtccagtc ccaccggcga
    49741 taatggctag cttgccacgg ctgtgaatat cctcaatagt catcttagct tctgaaacaa
    49801 aatcaaaagc cgagtaagac tcagttatct ctctaacatc gattaaatga tgaggaacag
    49861 ctgcctgctc ttctggacta gccttggccg tcccaatatc aagtcctcga tagacttgct
    49921 ggctatctcc actaaccact tcgccattaa agcactttgc aacttcaata gctagagccg
    49981 tctttccaac agcagtcggt ccaacaatca caattatttt tgttttcatc ttttttcctt
    50041 gaaaaattcc cattttttcg ttactattat tataacacaa aaaggtcagt cagaaaaatg
    50101 tgacctcttg aggaggctgg ctgattgaga atataaagga ggaagactca tggctaaagg
    50161 attcgctaaa ggtcttgtaa caggtgtcgc aggaactgtc gctgccgttg caggtgcagt
    50221 atacgcattt aaaaagaaag taatcgaacc agaagagcaa aaagcagctt tcatcgaaga
    50281 aaaccgtaaa aaagcagctc gtcgccgcgt atcacgttaa gaaacaaaag aagttgggat
    50341 tattctcaac ttcttttttc tattctttta aatagctagg tcaaacttca actgtggctt
    50401 aacagggtca taatccacca actcaaaatc ttctgctttg atatcaaaga aattagtccc
    50461 atcaggaaca tttaaaacca agcgtggttg gcagtttgac ggctcccgac ggagcaattc
    50521 ctgagcttgt tcaaattgat tatcatagat atggaggttg ttgatgaagt agaagaactt
    50581 cccaaccttc cagccaaaat gtttagcaat catcatctgc aaagccacat actgcatagc
    50641 gttgatgtgg tgggccacca gcatatcatt ggagcgctgg gtcaaggtcg catccagata
    50701 gatttcccca tcaacacgcc gaacatcaaa catggtctga aaggcgcacg ggagcagccc
    50761 atctgtttct tcgaaagctt ggtaatccca gagagaaata atattgcggc ggttccaagg
    50821 attggtttcc aactgtttga gaagcttatt gataatgtcg tgtttcttaa caacggcacc
    50881 atagcgctca ccaatggttc ccgtgtctcc aacttcccag tcattccagt agtgaacatt
    50941 gtacttgtca ttaagcactt ctaagctatt tgactggtct tggtaaatcc agagaacttc
    51001 tttgatggcg gatttgattg caatgggacg caaggttatg ataggaaatt ctcctttaga
    51061 taagtcgtac tcggaaaagg caccagttac atacttggaa ttagcaacag tcccatcctt
    51121 gtacttagga cgagcctgct ctgagaaaac accttccttt agaatgcgtt caatattctc
    51181 tttaaaaatc gtatctgctt ttgtcattta ctctcacctc attcattgtc ctaactagta
    51241 tagcataaaa aataaaagag gaacattact aactctaggt tagcattttc ctctctcatt
    51301 atcttattgc aatacaagtg atgctgctcc gataactcca gcgtcatttc ctagagttgc
    51361 aagagctaat ttagtagatg tgcgtacttg tgggaaagta ttttcgtcat agactttttg
    51421 aacaccttgt agaaggaatt ctcccgcagc tgacacacca ccaccgatga cgattgttga
    51481 tgggtttagg attgaaccaa tgttagcaca agcgattccc aagtaacgtg agaagttacg
    51541 gtaaacaatc aaagcaaggt cgtctccttc ttttgcgaga tcaaagacag tcttagcagt
    51601 tacttcttct ccgttatcaa tcaagcgttt caaggctgca tcgccttcgt attcatcggc
    51661 atagcgacga gtcaagttga caattcctgt tgcagaagcg actgtctcaa gacagccttt
    51721 cttaccgcaa gtacatgaga ttggctggtc aaagtcaaca gtgatgtgac ccaactcacc
    51781 tgctgcacca gcaacaccgt gaagcaattt gccttctgcg acgataccgc caccaacacc
    51841 agtaccgagt gtcataaaga caacatctgg ttggttatca ccagcaccca tccagcgctc
    51901 accaagagct gctacgttgg catcattatc gatgaaaaat ggaatgccca aagctttttc
    51961 aatcttttgt ttgattggtt gaagggtttt ccagttcaag ttgtaggcac cgataacagt
    52021 ccctttgtca cggtcaacca cacctggtga tcccattcca atgccttgga agtccgctgc
    52081 tgccaatcca agcaagtcca aacgatgttg aatagactca atcatatcat caacgatatg
    52141 acttccctca tccaaaatgt tggtcttgat tgaccatttt ccttggattt ctcctgctgt
    52201 tgttaagatt gcaaatttga tagaagttcc accaaggtca atcccaataa tcttttgact
    52261 cattatattc tcctttttca ttgtgtagta attgaaaatg cttacagtac tagtatatca
    52321 aaatccattc acttatgcaa aggtttgcgt aaatgaatta taaggaattt tttcgcctac
    52381 cagtatctgt taaccatcta aatgatcaat ggcatattga gctgcatcat ttgaaaattt
    52441 atcaaaatca gaagttaatt gtctatacat acgttttttt gacatgtgga ataacgaatt
    52501 ataacttttt gcctttccta aagcagcaga atattcacta ttgctatcat tactagaaga
    52561 agctgtactt gcttgacctt ccttccaaac tccgtcagcg ccaacataat aacgtccacc
    52621 atcaacccat tcattgacag ccattttacc atccgatttt agatagtaat ttccttgcca
    52681 tgtactataa gcataagaac catctgatgt caaataatac caagcttgat aggtggcatc
    52741 ataaacccat tcacctttag ccattttacc atctgatttc aaatagtagt ttccttgcca
    52801 tgcattgcga gcatatgaac catctgattt caagtaatac catgcttggt aagaagaatc
    52861 ataaacccac tcaccttgtg ccattttacc gtttgattta aggtaataag ctccttgcca
    52921 tgcatttttt gcataagaac catctgattt caaataatac caagcttgat aagaagagtc
    52981 ataaatccat tcactctgtg ccattttgcc atcagctttc aggtaatagt ttccctgcca
    53041 tgcatttttc actagatttc catttccatc aaaatagtac caagaaccgt cctgcttaac
    53101 ccaaccactt gctgtggatg aagttgtatc agtttgagtt gtagccgctt gttttgcttt
    53161 aaaagcaccc ttaggagcat ttttcaattc gcaagccaca ccatcatgat cgcggtctaa
    53221 cttggcagaa taaccaggtt ctccctcatg aagatccgaa tatccattag cccaagcttc
    53281 cttacagctc gaaaaatgga tgttttcttc cgccaaaact ggttgtgaaa acaaggctaa
    53341 aattggcaac gtcaccagac tcatttttaa aaatagacgt ttattcattt ctttctccca
    53401 taattatgat atcgatttca atattatttt atcaaactta tttcagcaat tcaaggaaac
    53461 ttctggtctt ttctacaaac tcctttggtt ttgccttatt caagacatga gggccatcag
    53521 gaatgatctg aaactgcgaa tctgttaaca gtctatggag agctttcata gaactaagat
    53581 tcggtttatc tttgctgcca caaattagta aggttggata ggagcaagtc cctgctatat
    53641 ccgttaaatc aagtgtcttc aattcctcag aaactccgac cataagagtc ttgtctgctc
    53701 cctgtttttc aaatactctt ttgggaagta gtttaaaaat cagcaactga agataaaata
    53761 ggatattccc tgctaattta agcgggcatc ctgacagaat caaagctcga agatttggta
    53821 aatcgtaact ggaaagttct agtgtcaggg cagcacctaa ggacaatcca atcaaaacaa
    53881 aaggttctgt ctcttgagct aggtgctgat aaactcgctc tttagcttgt tgatagttac
    53941 taactccaga aggaaataac tcgatagcct cagaaggata atctgtcagt agattccgaa
    54001 cttctttcca agactctgct gactgcccta acccatgcaa aaatatcaat ttcatctagt
    54061 tctcctcaag gcttagttca tacaagcctc tcactgcatt acagccgtaa atagcttctg
    54121 cttgggttaa atctgccaag gtcaagactt tctcttctac ctgtcctgtt tctagcaaat
    54181 actgacggta aattcctggt aagattccaa gtcggatagg cggtgtgtag agttttccag
    54241 cgattttcag aaccaaattt cctatagagg tttcaagcag ttctcctgac ttattgtggt
    54301 aaatcttctc ttgttctcct aggctcaaat gcggtcggtg agtggtttta aagtaggtaa
    54361 aggattgatt caaagcagct tcctgaaggc agacttgggc ctgacaaaag cttgtactga
    54421 gaggggttaa tacttgacga ttgacttcta tctctccaga tttgctaagg ctgattcgca
    54481 agcggtaatc tcgattagct tcacaatcct gacactcttc ctcaatcttg tgtcccaagt
    54541 cttctgcatc aaaaggaaaa gcaaaataac gactagcttt tctcagtctt tccagatgtt
    54601 gatcttcaaa cagcaggttc ttctggctga tttcccctgt cgtaatcagt tggaagcgag
    54661 cttgtttacg ataaagaact gctgcctttt gatgaacctc tcggtattca gattcccatg
    54721 tgctatccca agtaatccct ccgccaactc cataaatggc ttgacctttg tgaagttgaa
    54781 tggtacgaat ggccacatta aaaatccgtc gtccatttgg aagcaagaga ccaatcgttc
    54841 cacagtagac tccacgcggt tgaggctcca agtccttgat aatctccatt gtcgcaattt
    54901 tcggtgcacc cgttatggaa ccacaaggaa agagtgagcg gaagatttca acaaggtcca
    54961 catcctctcg caactgactc ttgatggtcg aagtcatctg ccaaacagtt gaatactgct
    55021 ctacctgaca cagacgctcc acgtgctcgc tcccaacttc agaaatacgg ttcatatcat
    55081 tgcgcaagag gtccacaatc atcatatttt cagagcgatt tttgggatcc tgttccaacc
    55141 aactggcctg ttcaagatct tcttggtcag ttaccccacg ctgagtcgtc cccttcattg
    55201 gtcgtgttgt caactcgcga tcattttgct caaaaaagag ctctgggctc atggaaatca
    55261 ctgccatctc gtcatgttcc acataggcat tgtagcccgc ctcctgctct accaccatac
    55321 gattgtagat ggcaaaagga ttggcactta acttttgctt gagttggacg gtgtagttga
    55381 cctgataggt gtctccctgc ctcaagtgat ggtgtatctg ggcaatggcc ttttcatagt
    55441 ctgctgcaga cgtcacttcc tgccaatttg agggcaaatc aatatcctca taagtcagag
    55501 gaatagggga agtttctacg ctatcatgaa cagtaaagta aagcaggtac tctcccagta
    55561 ggggatcctt gtgaactgct aatttttcct caaaagcagg tgcagcctcg tagctgacat
    55621 accccaccac ataataacct tgctcttggt agctttccac ttgtgccagc aaatctgcca
    55681 cttcttctac atttctcgtt ttcaactctt taataggctg ggcaaaggta tatctctccc
    55741 ctaaagtcct aaaatcaatc actgtttttc tatgcatacc ttaagtatag cataaaaagg
    55801 cagatacaga caaagctgat ctaccttttt acgattttat tcattctatg cttgtggtgc
    55861 agtaaataga tcaccagaga aaccgtctgt gtttttaagg agagctttaa agactttcga
    55921 tttcaagaca actgtatttc ggtatttgtc tttaatacta ctatcgttta gttccgttaa
    55981 atctttagta acagcctcat caaacatagt cttcaactgt tcataggttg aaatttgagt
    56041 gccattaatt tcaattggtg caaaaccttt tttagatttt gtaagaactt ccccatacca
    56101 ttgcttcttc caatcttcaa ggtttgaaaa ttggttatta gaaactttct taataatgaa
    56161 atcatcacct aatagaccgt tattttcttt attggctgca ccttgatgtt tgcttgaaac
    56221 atagtcaatg aacccatgtt catatccata gtaaccccac atacggaagg cgttatgttt
    56281 gaaggataga gaaccagggg caccttgact cgtattaccg ccataaatac cagccatcat
    56341 attaacattg acatatgccg taccaaagtc ctctgggtgg aagaccttat tacctggatt
    56401 tccgtgaatg gtcatgaaat tattatttac caagtcatcg atggtttcaa ggttagttgt
    56461 tttctcagcg tctatcaaat cacgcacttt gtcccattgg tgaggaccac ttagtttatt
    56521 tctgtccatt ggtcgacgtg tttcgcgatc aattttcttg aaccacttac tattgtcacc
    56581 tttaacctta ggaagaacag cctcagcttc tgcataatcg agcatcatca tagcttcatt
    56641 gtagttcttc atgtaatggt cgatttggtc acgtgtttga agtttggtag gatctggatt
    56701 ataccattgg tttccatcat ttgaacgttc aaatgccata tttaatccaa gtgcgccata
    56761 ttcaccttga tgtccatgtt ctgctggagt ttgtaacata ccttgagcaa atgcttcaag
    56821 atctgtaccc tgtcgatgtc tatgacctcc cagatatgcc attcggtcat ttacgtgggt
    56881 agtctcatgt gtaaaggcag atgtgccata ttcacttatt aaatccgaca taacaaaata
    56941 tacagcatcc ataggctgtg gatcagcaaa gatgtaagca tacgctccat acccatactt
    57001 ataatcatga tacttatcaa tacgtccaaa gaattcacga ataggtgcat aatccggttt
    57061 atcttttcga tgaccaaatc tatcaggcca accaccgggt gcaccatgat tatcccatac
    57121 aggagttgga actacatttt gactcttaag aagtttatcg cggacattat cagtggcaag
    57181 gcgtgaccaa aaatctaagt aattaacttg ctctttagca cgtttattga tttcactctt
    57241 gaacgattca cgtttttctt ctgtatcttt accatacttt tcaaacgaac taaatgagat
    57301 agtattatat gttgaaatca taaataaatg tgcatctttc aagttcagaa gcgataaaat
    57361 catgcgtcca tgttgtccgt tattaagtcc ttcatataga cgatattttt tattagcaaa
    57421 tgcagggtta gttgacggtt gttcaactac ataagcatta ttttcaatag ctttcttaaa
    57481 ccaaacattt atgtctgttt catttgtgaa tagtttcata ttgtaggtca agaagtcatg
    57541 taagtttcca gaaagagtat ttttcgccac cacttcacgg aaggactcct gtgtacgact
    57601 tcccttaata tagtcctctt ttgaaccaat ttctattaat cgatctaaaa cacttacatt
    57661 cttaccataa aaatctggtt tgaatagcat taattcttta atattgaagt tatcaaattt
    57721 cacaccgtaa taacgattta ggtatgttaa tcctaacagg acagcagctt tgttatcttc
    57781 aattttctta atcaaggcac gttttgcagc ttcatctgta ttcagttgat gatcttcatt
    57841 ttcaactaat tttgtcacaa atgtattaag atgatctttt acttctttaa agctttcttc
    57901 taagtaaaga ttcttaattg cattaactct gttatcccca gttcttccta atcgttgata
    57961 aattggatca gattgtaatt caattggact taaaatacct tcaatagcac taattaaatc
    58021 tgcacgatct ttaacaacca tatttggtgt atagacgact tcaccaagct ctgcgacact
    58081 gtattctttt acttgcttaa cttgagagtc tttaggagaa atcgtaaaga tatcttttgt
    58141 cttatctgcg taatgaacca taatatggtc agcatctgta aggtctgtaa taaagtcatt
    58201 acctttcatt gcagtcacag acaatacttc tttattcatt aatggactat cagttgtaag
    58261 cttgttccct tgattcacaa tccattcttt gttgtagaac ggttggagtt tttcaacatt
    58321 acgataaaca agctcacgat ttgcattata atcttgaatt gttttgtatt cttcatcacg
    58381 taatatacgg cgattcaact tatcaaccaa atgctcagtt acttcaaatg tatcagcagt
    58441 gatacccata tccttaattt tcttatcagc ttctacctgt gaaatttctt taattttaga
    58501 cgattgttta tgggttttat ctccagaact cacaccgata actgttgcat tattaggttt
    58561 aatccaattg cttacaaatt catcatccat atcattagaa ccaaagaaaa tatcaccacg
    58621 cttaacattc actaagctga tattgttatc aatggttccc caaggccagt ctttaccaat
    58681 taaaccgcct acatcacctc tagcaacatc aatagtacct ttggctacag aatttcttac
    58741 attagaccaa gcaccaacat ctcttggatt aaaatcatga gctaaatgtc ctactatagc
    58801 acctgcacga gtatttaaac ctttaagttc aacatctgca taagctttat ttaaattgcc
    58861 tcgataaatc tcagatgcaa tcccagccaa gttccaccct ttatcaccaa cagattgaac
    58921 ttttccgata aaagcaacat tagtcataat acctgcatca tctaatttat ccaaaatacc
    58981 cgcaacattg ttattaccaa cgatagtacc cgttacttta atattttcaa cagttgcatt
    59041 tttcactgtt tgagctaatg aagctaattg atttgcccaa ggcatattaa tattaacgtt
    59101 aattaaatta atatttttga tagaaccccc ttcaactcta tcaaataatg gacgagcagt
    59161 gttatgaatg gagaaatgct taccatcaac acttgttaag tgacctgtaa atttacctgt
    59221 tacatatgat ttacttggtg taggtacatt tgttgcattt aaatccgatc ctaatttaaa
    59281 ctcaccgtta ggatttttct gcatagcatc tactaaatct ttgaagttat agtaaacgtt
    59341 attttgcgat gctttgggtt tctctatgta ataagtgtat gtttgactca aactattatt
    59401 tgaatcacgt tggattaaat caggagctga agcagtaact ttaaataagg atgtctcctc
    59461 ctcagttact tcctctatat tagtaatggc aagccttgtt actttattat gattagtggt
    59521 aatttttaga taatatgacg ttagattttc tggaacagtt tctagaaggc tactatctgt
    59581 ttcatttcca ttctcatcca ctttcatcaa tcttgtttct ttaatatctt taatctcaac
    59641 ttttttaagg tctaactgaa cttctttatc ttctaatatt tcagtttctt caccgttacc
    59701 tcgatcatag accatggttg tggatagtgt ataaccttga taatatttca agttgtctaa
    59761 agtagcttgt aagttatttt cttctaccgt tacttcttta acaactgttc cagtattatc
    59821 ttttagagct actttaatcg atttaatttc tactccagct ggtttagtca atgtataact
    59881 agctgtcgca ctcttcttca agacatcttt atctgtttta gcccattcca aggttggttt
    59941 ctctaactct tttgtgccat tcttaataat tttgtcttga ggtttttcaa tcactgtttc
    60001 tgtgatagta ggagcgtcac ttgttttttc tccgcgaatt gttttatagg tttcagtaat
    60061 ttgtttctta tcgtttacac cttcttgagt tacttgtctt gttccgcgtt ttaaagtgtc
    60121 atcttcttgt tcttttgttt caaaaggaat gatttcttct cttgtctcaa ccgttgtccc
    60181 ttcaattggt tttgtaccac ggattacctg ttgatttaca ggctccttgg tgacttccgt
    60241 actggttgaa agaacttggt cagttttaac ccctcctatt gttttatagg ttgtttttgt
    60301 aacttgactt cctttttcac catttcgtag gacagtttct tcgtccgtgt acttggttgg
    60361 gtcctcagtc gtttcagttt tatagtcaag ttctgtagtt gattcttcaa cgagtgttcc
    60421 ttcagtcacc ttatactcag gtaattgttc tggaacaaga gcctcaccca cgtaatcttc
    60481 ttcttgcgtc cccttagctg ttttagtctc ctcttttggt tctacagttt cttcagcctt
    60541 ggtatctgga gttgactctt cttgtttcgg tgtctcttcc gctcccctat cttctttagg
    60601 attgtcttct tgtgatgatt cttttggtgt acttggttgc tcagcttgtg taggttgcac
    60661 gggttgttct gggacttttg cttgttctac tggtggttca acttttgatt cctcagctgg
    60721 tttgtctgat ggttgacttt ctggcttaac tgctactttt tcctctgatt ttgactcaac
    60781 ttctccacct acttcttcaa ctggagctgg ttctgctgaa tcttctttcc cctcttctac
    60841 tttaggaagg gtgtcgtcag taggttttac ctccgatttt ggttcttcct ttggactttc
    60901 ttctgttcta ggtgcttctt cttttggagt ttcctctgtc tctactactt ggttttctgt
    60961 cctagcttgc tcctgatttg ttgttgattg aggagtctca acttcgacta cagtcacctc
    61021 tccaggtttt gctgaggttt cttctaaaac agtgtccaag ccaagcgttt tgaggatgtc
    61081 acctgataga taaccaacat agcgatagcc atccatttca acaacaccct ctcgactagc
    61141 cagcgctaag gtcgcaactg ggtctacagc ccctgcacta ggaagaacta ccaatcccat
    61201 agctccaact agaaagacgc tagcaatttt ctttctcttg tagattaaaa gcaagctccc
    61261 aacagtcagc aaaccaaaag ctgtcaaaac agatgcttct gtccctgttt gaggcaactg
    61321 atctttttga tacaccaaac catatacaac ttcattcctg tcaggctttc ctgtctgaat
    61381 taaatcttta gcttcttgtg aaataatctc tttatttaca tagtgatagg tagctgcgtc
    61441 cactacagaa ggagccatca aaaggcttcc aagaaataca gagcctacaa ctcccttaat
    61501 cttacgaatt gaaaaacggt cttttttaaa cactttcatc tcctttattc attctcaaga
    61561 ctttctaata gcatcttgcg gatagtgcgc acgcgcacct ccgattaatt ttggacgact
    61621 agccagtgcc gttacatggg catgaccaat ctctctcaaa atagggcgaa tcggaacctg
    61681 aacatgcttg acatgcatgc caattgcagt gtctccgata tccaatccag catgagcctt
    61741 gataaattca acctcaactg gatcctgcat aaacttaaag gctgccaact gccccgaacc
    61801 tcctgcatga agagtaggat ggacactgac aatttccaga tcaaactgct ctgccacctg
    61861 acgttcaaca acgagagccc gattgacatg ctcacaacct tgaactgcta aatggatacc
    61921 tctactacct agaataccca agatagtctc cactatcagc tcaccaatct cttgactgga
    61981 ttctttccca atctgaccac ctagcacctc actagaagat agacctaaaa caaaaaggac
    62041 cccctgcttc aaattggtct tttctaaaac atcttccact acctgacgtg tttctctttg
    62101 aatctgtgtc tcgttcatct ctgttacctc tgttgtcact cttctatcat accgtttttt
    62161 cttgttttta gcaagataga caacctataa agtctgccca attacgcata aaactcccag
    62221 aattgactgg gagttagcta gtttctattc tatttatata tatttcaact ttcgttcctt
    62281 tttggggtct agaatcaatc ttcatctggt aattggctcc aaaatgaagt ttgagccgtt
    62341 gatcgacatt ttgaagacca actcccccac gtttgagttg actttgacta ctatcaccag
    62401 catcttggaa gccaacgcca tcatcctcaa tacggatgac caatcccgaa tcctgtttct
    62461 ggacagaaag tttaatatgg ccctgacctt ccttttcctt aatgccatgg taaagagcat
    62521 tttctacaag gggttgtagg accagcttgg gtaagactaa attatcaaag gcaacatttt
    62581 cattaatttc gtattccagc ttatctccat agcgttgttt ctggataaag agatactggc
    62641 ggacatgatt gatttcgtca gagagacaaa tcaagtcctt gccttgattg agcgccaagc
    62701 ggaaataggt tgccaaggac ttggtcacct gcaccactcg ctgactatca tgaaattcag
    62761 ccatccagat gatggtgtcc aaagtgttat agaggaaatg tggattaatc tggctcgaaa
    62821 gggcttgaag ttggtactga cgggtcgttt cttcctggct acgaatagct accatcaact
    62881 gatcaatctg atccaacata gcattaaatt ggcgagttac ttctctcagt tcataggcac
    62941 caacttcctt ggcacgaaga ttttgagcac cagaagcaat ttccaacatg gtttctctca
    63001 aatccttcaa aggagcaatc cagcgtttaa gactgaacca cactaagcag agacaaacaa
    63061 gaagagatgt gacactggcc ccaagcaagg tccacaagag ctgactccga acctggtcta
    63121 acttttccaa tgatgacacg ccaagtaccg tccaatcagt tcctgcaatc ttctcttgac
    63181 tgacgtagga tttgtgacca ggagtataac cctgacctgt ctcgatgtag ggtttcatag
    63241 cctccatttt gctagacgaa ctataaactg tgtgttgagg atggtagaca aattcatggt
    63301 tttcattgat aatgaaggca aagccctgct gccccaactg gagttgattg agataggctt
    63361 ccagagtttc ataagaaata tccaaacgaa gcacaccaag attggctccc tttgcatcaa
    63421 caagttcttg agtgacagaa atgacccact gactatctga tttacgagct ggagtcaaaa
    63481 caggcatagc tccctgatga atagcctttt ggtaccaatc ctcagccatc atatcagagg
    63541 aagttttcat ctgcacactg tcatctgtag aaatgacctg accagatttg gtcaccagca
    63601 caacagtttt caagtcctta tctgacttca agatggtcaa aaacaaatct cggattccct
    63661 cgaccttgtc ttgactggga ttctcagcat aggccagaac atccgtctgc tgggtcaaac
    63721 cagtcgaggt ggtttctagt tttttgatat aagactgaat aaagtggcta gtctggctga
    63781 tggtcgtttg gctgttgccc tcaatggtgg cctcaatggc tgaagaactt gattgatagt
    63841 agaaagttcc aaccagagct aggagaatga gaaagaccag aaagatggaa ataaccattc
    63901 taactaaaag agaagaacgc ttcatcggtc ttctcccttc ttaaactgac gaggtgtcac
    63961 acctgcaatc tgcttaaaac gttgggtaaa atagttcata tcttcaaaac caaccttctc
    64021 tgcgatctca taaatcttca gatctgtagt taaaagcaag agcttggctt gtttaacacg
    64081 ttctctcacc agataatcct gaaaaggcaa gcccaactct ttcttaatca aggaactcag
    64141 ataggtcgga ctaaaaccta agtcactggc taaagacttt aaactaaatt ggctatcagc
    64201 cagatgagac tggattttct gggccatgtt tccttcaaac ctattagtca ataaatcttg
    64261 taactgctct tctttctctt ccttgtctag tttttgtttg attttcccca acatttcctc
    64321 aatatcctga cgagaaaagg gtttgagcag gtagtcgtcc acacctagtt tgacagcaga
    64381 caaggcataa tcaaaatcat cgtaacctgt taaaaagacc aaatgaacct gaggataggt
    64441 ttctcgtacc agactggcca actggatgcc atttagatga ggcatgttga tatcggttaa
    64501 aatgatatct ggcacctgct tttggatcaa ttcccaagcc tgccttccat tttcagcctg
    64561 accgatgatt tccatatcgt aggctgctac attgaccagt ttagtcaaac cttgtcttac
    64621 cagatattca tcttctacga ttaagattgt gtaggtcatg ctctgctcct ttaccactta
    64681 ctagtatcag tatagcaaaa ttctcctcta actgcttagg aaagacctct tatactcaat
    64741 aaaaatcaaa aagtaaacta ggaagatagc cacaggtttc tcaaagtata gctttgaggt
    64801 tgtaaataaa actgacgaag tcagatcaaa gtatagcttt gaggttgta
//
LOCUS       DAVBIC010000005        51676 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.005, whole genome shotgun sequence.
ACCESSION   DAVBIC010000005 DAVBIC010000000
VERSION     DAVBIC010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 51676)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51676)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51676
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.005"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            complement(54..362)
                     /locus_tag="VQ664_000296"
                     /pseudo
     CDS             complement(54..362)
                     /locus_tag="VQ664_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996568.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose 4,6-dehydratase"
     gene            complement(604..900)
                     /locus_tag="VQ664_000297"
     CDS             complement(604..900)
                     /locus_tag="VQ664_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2788531.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYELTEYSKMK"
     gene            complement(884..3043)
                     /gene="pfbA"
                     /locus_tag="VQ664_000298"
     CDS             complement(884..3043)
                     /gene="pfbA"
                     /locus_tag="VQ664_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HET2788532.1"
                     /translation="MLKIVKKLEVLMKYFVPNEVFSIRKLKVGTCSVLLAISILGSQG
                     ILSDEVVTSSSPMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNS
                     ISSNGTIRSNSQLDNRTVESTVISTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAV
                     GDGIHDDRQAIQDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILN
                     GINIKNHPSIVFMTGLFTDDGAQVEWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLI
                     NSSGAFAIGNSNNVTIKNVTFKDSYQGHAIQIAGSKNVLVDNSRFLGQALPKTMKDGQ
                     IISKESIQIEPLTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTL
                     STQNPSNIKILNNHFDNMMYAGVRFTGFTDVLIKGNRFDKKVKGESVHYRESGAALVN
                     AYSYKNTKDLLDLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVIN
                     NNSKETEQPNIELLRVSDNLVVSENSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYI
                     SFIKSNANGKESVIRDSDGNFNIVTENGLYKIVTNNLSDKNEKEKNKEEKQSNSNNVI
                     DSNQKNGEFNSSKDNRQMNDKIDNKQDNKTEEVNYKIVGDGRETENHINKSKEIVDVK
                     QKLPKTGSNKIMELFLTVTGIGLLLTLKGLKYYGKDK"
     gene            complement(4173..5399)
                     /locus_tag="VQ664_000299"
     CDS             complement(4173..5399)
                     /locus_tag="VQ664_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="HET2788533.1"
                     /translation="MPNYNIPFSPPDITEAEIAEVADTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILRVFEVGPGDEVIVPAITYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSTYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWKANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAGSRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            complement(5442..6134)
                     /locus_tag="VQ664_000300"
     CDS             complement(5442..6134)
                     /locus_tag="VQ664_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HET2788534.1"
                     /translation="MLKWEDLPVEMKSSEVESYYQLVSKRKGSLIFKRCLDWVLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGNLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSTEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMRYNLAYLREFSFFGDI
                     KIMFQTVFKVLK"
     gene            complement(6320..8071)
                     /locus_tag="VQ664_000301"
     CDS             complement(6320..8071)
                     /locus_tag="VQ664_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2788535.1"
                     /translation="MQNKQEQWAVLKRLMSYLKPYRLLTFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLVYANRSVALDALFLRPAMSLLKLLGYAVLMAYFGYRGLSIG
                     ITAGTMYAFIQYINRLFDPLIEVTQNFSTLQTSMVSAGRVFALVDERTYEPLQENGQA
                     KVQEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQEISDEQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLALGG
                     TYHKMYSLQAGAMAYTL"
     gene            complement(8061..9806)
                     /locus_tag="VQ664_000302"
     CDS             complement(8061..9806)
                     /locus_tag="VQ664_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2788536.1"
                     /translation="MSIIQKLWWFFKLEKHRYLVGIVALVLVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSPAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYATSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLLFVGSSYVLTLLVGSLMVQEGQITVGN
                     LVTFISYLDMLVWPLMAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     RLEYAIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGAI
                     YLNGHDIRDYRLTELRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSEVEEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILNPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADFILVLQNGQIIERGRHEDLLAMDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            complement(10012..10308)
                     /locus_tag="VQ664_000303"
     CDS             complement(10012..10308)
                     /locus_tag="VQ664_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001276342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HET2788537.1"
                     /translation="MSASDVALKLRSQGIFQMKQVKRAVQEQNGQLIVVQMGDENPKY
                     PVVTDGVIQVDVLESIGRSEEWLLDNLSKQGHDNVANIFIAEYDKGAVTVVTYE"
     gene            complement(10461..10917)
                     /locus_tag="VQ664_000304"
                     /pseudo
     CDS             complement(10461..10917)
                     /locus_tag="VQ664_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            11051..11878
                     /gene="xth"
                     /locus_tag="VQ664_000305"
     CDS             11051..11878
                     /gene="xth"
                     /locus_tag="VQ664_000305"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HET2788538.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTISFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDVKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            11890..12033
                     /locus_tag="VQ664_000306"
     CDS             11890..12033
                     /locus_tag="VQ664_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HET2788539.1"
                     /translation="MDYNAVIPEFLVSNIEQSRSFYCGLLGFRIEYQRSEENFLFLLK
                     SVN"
     gene            12033..12272
                     /locus_tag="VQ664_000307"
     CDS             12033..12272
                     /locus_tag="VQ664_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HET2788540.1"
                     /translation="MLEEGTKDQLAELTYPFGRGVNLSFGIKDVPKLYQKVMEANYPI
                     YRPLTKRKFRVSDPYIYPHKFAVLDPDGYFLRFSE"
     regulatory      12656..12751
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            13151..13732
                     /locus_tag="VQ664_000308"
     CDS             13151..13732
                     /locus_tag="VQ664_000308"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HET2788541.1"
                     /translation="MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGKVFAE
                     KFAAAGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     gene            13732..14994
                     /locus_tag="VQ664_000309"
     CDS             13732..14994
                     /locus_tag="VQ664_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HET2788542.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSGAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LSAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPTP
                     LYFGMPTFEISSIVMMCIIATVSMVESTGVYLALSDITKDPIDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIVVASLLAIVLNAVLNHKKK"
     gene            complement(15081..15947)
                     /locus_tag="VQ664_000310"
     CDS             complement(15081..15947)
                     /locus_tag="VQ664_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II restriction endonuclease"
                     /protein_id="HET2788543.1"
                     /translation="MKQTRNFDEWLSTMTDTVADWTYYTDFPKVYKNVSSIKVALNIM
                     NSLIGSKNIQEDFLDLYQNYPEILKVVPLLIAKRLRDTIIVKDPIKDFYFDFSKRNYS
                     IEEYTMFLEKSGIFDLLQNHLVSNLVDYVTGVEVGMDTNGRKNRTGDAMENIVQSYLE
                     AEGYILGENLFKEIEQNEIEEIFSVDLSAITNDGNTVKRFDFVIKNEQVLYLIEVNFY
                     SGSGSKLNETARSYKMIAEEIKAIPNVEFMWITDGQGWYKAKNNLRETFDILPFLYNI
                     NDLEHNILKNLK"
     gene            complement(15934..16704)
                     /locus_tag="VQ664_000311"
     CDS             complement(15934..16704)
                     /locus_tag="VQ664_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HET2788544.1"
                     /translation="MTKPYYNKNKMILVHSDTFKFLSKMKPESMDMIFADPPYFLSNG
                     GISNSGGQVVSVDKGDWDKISSFEEKHEFNRKWIRLAKEVLKPNGTVWISGSLHNIYS
                     VGMALEQEGFKILNNITWQKTNPAPNLSCRYFTHSTETILWARKNDKKARHYYNYDLM
                     KELNDGKQMKDVWTGSLTKKVEKWAGKHPTQKPEYLLERIILASTKEGDYILDPFVGS
                     GTTGVVAKRLGRRFIGIDAEKEYLKIARKRLEAENETN"
     gene            complement(16730..17584)
                     /locus_tag="VQ664_000312"
     CDS             complement(16730..17584)
                     /locus_tag="VQ664_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
                     /protein_id="HET2788545.1"
                     /translation="MKIKEIKKVTLQPFTKWTGGKRQLLPVIRELMPKTYNRYFEPFV
                     GGGALFFDLAPKDAVINDFNAELINCYQQIKDNPQELIEILKVHQEYNSKEYYLDLRS
                     ADRDERIDMMSEVQRAARILYMLRVNFNGLYRVNSKNQFNVPYGRYKNPKIVDEELIS
                     AISVYLNNNQLEIKVGDFEKAIVDVRTGDFVYFDPPYIPLSETSAFTSYTHEGFSFAD
                     QVRLRDAFKRLSDTGAYVMLSNSSSALVEELYKDFNIHYVEATRTNGAKSSSRGKISE
                     IIVTNYEK"
     gene            complement(17741..18145)
                     /locus_tag="VQ664_000313"
     CDS             complement(17741..18145)
                     /locus_tag="VQ664_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HET2788546.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVTGQRSEERRVRI"
     gene            complement(18215..19696)
                     /locus_tag="VQ664_000314"
     CDS             complement(18215..19696)
                     /locus_tag="VQ664_000314"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HET2788547.1"
                     /translation="MTLVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKDQLVEEAVRLETIEDSQTAREILGTELMDLVTPCPSQVNRDFWEAYAYSPE
                     QAIEDFYQLSQKNDYIKLKAIAKNIVYRVPSDYGELEITINLSKPEKDPKEIAVAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARSNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVEQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKTFRFAGFEQVKAGIIKWPMSVLRLTSDSKEDLINLADKIFQEWRQYSDSSVQ
                     ILAETDGTPHHTITPIARKRDGQFELDLVLRDNQTSADHPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFARVLEDAGVYKQTEQGQTAFMRFVEHVGILLD"
     gene            complement(19715..20893)
                     /locus_tag="VQ664_000315"
     CDS             complement(19715..20893)
                     /locus_tag="VQ664_000315"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HET2788548.1"
                     /translation="MAQHLTTEALRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLERLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAVDQYSYLIKDENRLKRAR
                     HAVFENQRTLKAQAALQAGDLETFGRLMNASHVSLEHDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEAFKEAVGKHYEEVVGYAPSFYIAEVAGGTRVLD
                     "
     gene            21058..22065
                     /gene="galR"
                     /locus_tag="VQ664_000316"
     CDS             21058..22065
                     /gene="galR"
                     /locus_tag="VQ664_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HET2788549.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIQDKRLENFRNYSQAKGIYHDELVFQGN
                     FTAQSGYDLMKEAIQNLGDQLPPAFFAASDSLAIGALRALQEAGISLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHDRKIPSLTMLGTRLTLRESTLNQ
                     E"
     gene            complement(22111..23148)
                     /locus_tag="VQ664_000317"
     CDS             complement(22111..23148)
                     /locus_tag="VQ664_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HET2788550.1"
                     /translation="MKSAVYTKAGQVGLASIERPQIIEADDVIIRVVRACVCGSDLWR
                     YRNPETKAGHKNSGHEAIGIVEEAVEAITTVKPGDFVIVPFTHGCGECDACLAGFDGS
                     CDNHIGNNLGGDFQAEYIRFHYANWALVKIPGQPSDYTEGMLQSLLTLADVMPTGYHA
                     ARVANVQKGDKVVVIGDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVV
                     AERGQEGITKVREILGGGADAALECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRAL
                     GSTFMQNISVAGGAASATTYDKQFLLKAVLDGDINPGRVFTSSYKLEDIDQAYKDMDE
                     RKTIKSMIVIE"
     gene            complement(23149..23502)
                     /locus_tag="VQ664_000318"
     CDS             complement(23149..23502)
                     /locus_tag="VQ664_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HET2788551.1"
                     /translation="MNIKSASDLLGISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            complement(23746..24636)
                     /locus_tag="VQ664_000319"
     CDS             complement(23746..24636)
                     /locus_tag="VQ664_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HET2788552.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGVFGSSAVLADSVHDLGDA
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVTAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALPRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     ASLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            24769..25305
                     /locus_tag="VQ664_000320"
     CDS             24769..25305
                     /locus_tag="VQ664_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HET2788553.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKGYEATTVQDIIDLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTEDYLAHLFLHFHKNQDHITSLLFS
                     KNDYFLRQLHKELEHHVYSVLADNLKEAHPNLPTSYLQHLVMSNFIETLTWWLKKGQD
                     FTDQEVVQFYLDLLIPKN"
     gene            complement(25472..26278)
                     /locus_tag="VQ664_000321"
     CDS             complement(25472..26278)
                     /locus_tag="VQ664_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HET2788554.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLLN"
     gene            complement(26623..28143)
                     /locus_tag="VQ664_000322"
     CDS             complement(26623..28143)
                     /locus_tag="VQ664_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HET2788555.1"
                     /translation="MTNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVFL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPNLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLAALIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVAL
                     LLGLSYSPALLVQKEKENLVIAGKIGPEPEILANMYKLLIEENTSMTATVKPNFGKTS
                     FLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVATMEPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELERVLNTLAGKITESQMSQLNYQVGVEGKSAKQVAKEFLQEQGLLKK"
     gene            complement(28136..28864)
                     /locus_tag="VQ664_000323"
     CDS             complement(28136..28864)
                     /locus_tag="VQ664_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2788556.1"
                     /translation="MIEYKNVALRYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVAENIALIPEM
                     KGWSKEEITKKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKIFLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVA
                     NPETILKAPATDFVADLFGGSVHD"
     gene            complement(28879..29643)
                     /locus_tag="VQ664_000324"
     CDS             complement(28879..29643)
                     /locus_tag="VQ664_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HET2788557.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGDTYIQHSTGVPDGK
                     EGFAAFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     RIVEHWDVVDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTEIFQNGELEQW
                     SDYVADDLIQHNHDIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLENGKIVEHWDNKEVMPKVEDLTNRGKF"
     gene            complement(29647..30090)
                     /locus_tag="VQ664_000325"
     CDS             complement(29647..30090)
                     /locus_tag="VQ664_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HET2788558.1"
                     /translation="MKDSHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKFQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKGNEV"
     gene            complement(30772..31068)
                     /locus_tag="VQ664_000326"
     CDS             complement(30772..31068)
                     /locus_tag="VQ664_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HET2788559.1"
                     /translation="MAEPNLESLIKDLYNHARHDLSEDLVAALLETAKKLPTTNEQLQ
                     AVRLSGLVNRELLLNPKHPAPELLNLARFIKREEAKYRGTATSALMYEELFKML"
     gene            complement(31090..32154)
                     /gene="pepA"
                     /locus_tag="VQ664_000327"
     CDS             complement(31090..32154)
                     /gene="pepA"
                     /locus_tag="VQ664_000327"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HET2788560.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKAEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
     gene            32555..33256
                     /gene="galE"
                     /locus_tag="VQ664_000328"
     CDS             32555..33256
                     /gene="galE"
                     /locus_tag="VQ664_000328"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HET2788561.1"
                     /translation="MTKTILVTGGTSYIGSHTVKALLNAGYKVHVLDNLSTGNRAAVD
                     SRASFKELDVYDASALKAYLEENQIDAVLHCAGEIVVSESIENPSKYFTANVAGMNQV
                     LKVLSEVGIQKIMFSSTASLYGNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMAN
                     RYDWKYVIFRYFNVAGAEMDASNGLRVKNPTHIIPNINKTALGQNDSLKIFGDDYDTR
                     DGSCIRDYIYVLDLA"
     gene            33679..34638
                     /locus_tag="VQ664_000329"
     CDS             33679..34638
                     /locus_tag="VQ664_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2788562.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFVSSIVFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKEISESLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKRYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLGFILLLWRGGRKDAD"
     gene            34628..35584
                     /locus_tag="VQ664_000330"
     CDS             34628..35584
                     /locus_tag="VQ664_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HET2788563.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSLFFLTLQGYLKTLMKQDLVFILLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILVGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRSRQ"
     gene            35581..36333
                     /locus_tag="VQ664_000331"
     CDS             35581..36333
                     /locus_tag="VQ664_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2788564.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINMASQYADEIVAFKDGQVFSKGS
                     TDQIMQADLLSQLYEIPITLADINDKKICIYS"
     gene            36429..37394
                     /locus_tag="VQ664_000332"
     CDS             36429..37394
                     /locus_tag="VQ664_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2788565.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEVTI
                     KSSLDEVKLSKVPEKIVTFDLGAADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETGTQKAKEELAKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTKFEDSRHGQEVSFESVKEINPAILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(37619..37861)
                     /gene="yidD"
                     /locus_tag="VQ664_000333"
     CDS             complement(37619..37861)
                     /gene="yidD"
                     /locus_tag="VQ664_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HET2788566.1"
                     /translation="MKRILIAPVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFK
                     GVLMGLARILRCHPWSKTGKDPVPDHFSLKRNQEGE"
     gene            complement(37861..38583)
                     /locus_tag="VQ664_000334"
     CDS             complement(37861..38583)
                     /locus_tag="VQ664_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HET2788567.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVANKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLTIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            complement(38570..39139)
                     /locus_tag="VQ664_000335"
     CDS             complement(38570..39139)
                     /locus_tag="VQ664_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HET2788568.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKSQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            complement(39158..39886)
                     /locus_tag="VQ664_000336"
     CDS             complement(39158..39886)
                     /locus_tag="VQ664_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HET2788569.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            complement(39886..40626)
                     /gene="xerD"
                     /locus_tag="VQ664_000337"
     CDS             complement(39886..40626)
                     /gene="xerD"
                     /locus_tag="VQ664_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HET2788570.1"
                     /translation="MPMRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETS
                     LKIYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEIL
                     YLDSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQQRIVT
                     IPTALLSELEPLMGQTYLFERGEKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFIL
                     RQIENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            complement(40617..41078)
                     /locus_tag="VQ664_000338"
     CDS             complement(40617..41078)
                     /locus_tag="VQ664_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HET2788571.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDAEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            complement(41075..41596)
                     /locus_tag="VQ664_000339"
     CDS             complement(41075..41596)
                     /locus_tag="VQ664_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HET2788572.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWLEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            complement(41572..42543)
                     /locus_tag="VQ664_000340"
     CDS             complement(41572..42543)
                     /locus_tag="VQ664_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HET2788573.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYKTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGKSSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            complement(42540..43334)
                     /gene="racE"
                     /locus_tag="VQ664_000341"
     CDS             complement(42540..43334)
                     /gene="racE"
                     /locus_tag="VQ664_000341"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HET2788574.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIYVEHVEL"
     gene            complement(43541..43789)
                     /locus_tag="VQ664_000342"
     CDS             complement(43541..43789)
                     /locus_tag="VQ664_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HET2788575.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            complement(43931..45556)
                     /gene="treC"
                     /locus_tag="VQ664_000343"
     CDS             complement(43931..45556)
                     /gene="treC"
                     /locus_tag="VQ664_000343"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HET2788576.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTGNGIGDFRGIIGKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCIGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWAPFGDTGKYYLHLFDETQA
                     DLNWRNPNVRKELFKVVNFWRDKGVKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQMLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDASENAGFSTGTPWLKAGKSYKDINVENEIQGPIFTFY
                     QDLIRLRKEMPIISEGSYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            complement(45734..47701)
                     /gene="treP"
                     /locus_tag="VQ664_000344"
     CDS             complement(45734..47701)
                     /gene="treP"
                     /locus_tag="VQ664_000344"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HET2788577.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGNDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QRVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKWLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFAYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKTEGDTNLQAEFVAQEEAEFVNHEPVELTSVEII
                     SPLTGQVKELSQATDPIFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVTVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATIPGTYPTTIQAGASLMVATRI"
     gene            47886..48596
                     /gene="treR"
                     /locus_tag="VQ664_000345"
     CDS             47886..48596
                     /gene="treR"
                     /locus_tag="VQ664_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HET2788578.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
     gene            complement(48629..49432)
                     /locus_tag="VQ664_000346"
     CDS             complement(48629..49432)
                     /locus_tag="VQ664_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000157668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2788579.1"
                     /translation="MASLLTLENIHKTFEAGTVNENHVLKGLDLEVEEGDFISVIGGN
                     GAGKSTLMNILAGNLSVDEGDLLLAGKSIKHLSVRKRAKDIARVFQDPKMGTASRLTI
                     EENMAIALRRGQKRGLGWGVKEKDRIQFQEALKELNIGLENRLKVDTQYLSGGQRQAL
                     TLVMAALVKLKLLLLDEHTAALDPKTSQMVMDLTQKIVEYHQWTTLMITHDMNHAIEY
                     GNRLIMLYQGKIVVDVKGEEKKHLTVEDLMHLFQKNSGQSLVSDELVLG"
     gene            complement(49445..49873)
                     /locus_tag="VQ664_000347"
     CDS             complement(49445..49873)
                     /locus_tag="VQ664_000347"
                     /inference="COORDINATES: protein motif:HMM:NF014684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2788580.1"
                     /translation="MKTEIGLVLRSTGDNIPMSEANGVNVNTMKIVGYMISTGLIALC
                     GSLFAQNDGFSDVTSGTGTIVVGLSSEVLIHDLTIGGRLLSIGIGAIVYRLIILNIYE
                     IPNLDQNLVRLFNAILLALVLFAPALQKRLKIRGLKLRNE"
     gene            complement(49882..50322)
                     /locus_tag="VQ664_000348"
     CDS             complement(49882..50322)
                     /locus_tag="VQ664_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2788581.1"
                     /translation="MNFVLSSLSEGLLWSIMAIGVYLTFRILDIADMTAEGAFPMGAA
                     IVVSQIQAGANPWLATLLALLAGMVAGLISGMLHTKMKIPALLTGIVTLTGLYSINIK
                     IMGSVPNLSLGDSATVFKQLASLGLTNEGAVFSLSLVCLLLVWF"
     gene            complement(50367..51272)
                     /locus_tag="VQ664_000349"
                     /pseudo
     CDS             complement(50367..51272)
                     /locus_tag="VQ664_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000512061.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
BASE COUNT        15175 a        11736 c         9477 g        15288 t
ORIGIN      
        1 attaaaaggt taagtaattt ttccaaaata cagcactcat atagacagta tcatcaatta
       61 tagccattgg gattttttga ttgccaattc catgtatctc tacacatgtc ttcaatcgat
      121 tttgttgtcc tccaatttaa ttccttatat gctttgtctg catttgcata ataagttgca
      181 acgtctcctg aacgtcttgg aactatttta taaggaatag ggatcttatt aacactttca
      241 aatgtattta caagttgtaa tacactagtg ccttctcccg agcctaggtt atagatataa
      301 acatctgttt tttcagatac tttttctaaa gcttttatat gtcctattgc taaatctact
      361 acttgaatct tttatctcat ttttcccttt ttcaaataag ttatctactc tatgatcagt
      421 tatttccatt tcgtttacta acatgacgca gtcacctagc atcatatact ccaacttttt
      481 ttctgaaagt ttagcaaata ttggtaagcg ataatatagt atattgaaac tagaatagta
      541 cacctctact tctaaaacat tgttagaaat cgatttgact gtcctgattg atttgtccta
      601 ttattatttc attttactat actctgttaa ttcatatgag tttaaaccga tttcatcttt
      661 aacctcgagt aaagcagttt caaatatttg tttaagagtt tttgattctt tacaattaac
      721 cgacaaactt tctgataaaa tatgtacaac ttctgagact gaataaccta tctcctcttt
      781 agaattatat aaatctgtag ctccaccaat aatccaaaaa tactgatttt gtgaacctac
      841 aatatcctca ttttctacgg aacttccttg tatcgaacaa attttattta tctttaccat
      901 aatacttcaa cccttttagt gtcaaaagta aaccaattcc tgtcactgtt aagaatagtt
      961 ccataatctt gttcgaacca gtctttggta atttttgttt tacatctact atttctttag
     1021 atttattaat atgattttca gtttctctgc catctccaac tattttatag tttacttctt
     1081 ctgtcttatt atcttgttta ttgtcgatct tgtcattcat ttgtctatta tctttacttg
     1141 agttaaactc tccgttcttc tggttactat caattacatt atttgaatta gattgttttt
     1201 cctctttgtt tttttctttt tcgtttttat cacttaaatt atttgttaca attttgtaaa
     1261 gcccattctc cgttacaata ttgaaattac catcgctatc acgtataaca gattctttcc
     1321 catttgcatt agatttgatg aatgatatat acttaccgga taaattataa aattggttat
     1381 ttaaaacggt tattttaccc tttgaatcct caataacaat tccttcttta ccaccgaata
     1441 tactattctc tgagactact aaattatcac taactcgtaa taattcaata tttggttgtt
     1501 ctgtttcctt agaattatta ttaattacat tttttgttac agtaatatct gatacttttc
     1561 ctaaatattc tgcactatct tttgcaactc gtatcgcttt tgttttagga tcggcaatat
     1621 taaatatatt ttcggcgata accacctgtt tatttaaatc taataggtct ttagtgtttt
     1681 tatagctata agcatttact aaagctgctc cgctttctcg ataatgtaca ctctctcctt
     1741 taactttctt atcaaagcga tttcctttga ttaatacatc agtgaatcct gtaaaacgta
     1801 cacctgcata catcatgtta tcaaaatgat tatttaaaat tttaatatta gaggggttct
     1861 gtgtcgacaa tgtttgatag tgtgtgccaa ttgctgttac taattcccca gatttatcac
     1921 ttttgccaaa ataggaattt tgaatagtca cattttcaga ttttttccca tcatcattca
     1981 aggcataagg aaaacctttt ctagttaatg gttcaatctg aatgctctcc ttacttatga
     2041 tttgcccatc cttcatcgtt ttgggtaagg cttgcccaag aaaacgagaa ttatcaacta
     2101 atacattttt cgaacctgca atttgaatag catgcccttg ataactatcc ttgaatgtta
     2161 cattttttat agttacgtta tttgaattcc caatagcaaa tgcacctgaa gaatttataa
     2221 gtggtagatt ttttgcttta gttccttctt cattcaaagc accgttcata tcaatcgtac
     2281 caccagaata actaatatct tctgttgggc cccattctac ttgcgcacca tcatccgtaa
     2341 ataaacctgt cataaaaaca atggaagggt gattcttaat atttatacca tttagaattg
     2401 tagctttctc attcaattct aagtgtgtat gactttttaa aaaaacaatt tcttttacta
     2461 aataagttcc ttcaggaaaa tatacatttc ctccacctag cccttgagct gcagcatcta
     2521 ttgcatcttg aattgcttgt cgatcatcat gaatcccatc acctaccgca ccataatctt
     2581 ttacacttaa agcagtatct tcaaattctt ttttgataat tctgtcactt ataacatctt
     2641 ccttataact cttattttca ttagtagata ttactgtaga ttcaactgtt ctgttgtcta
     2701 attgtgaatt ggaacgaata gtaccattag agctgatact attaacactt aacgaattat
     2761 ctaaaccatt agtggttgaa ttagaggcaa tcatttcagc agaacgattt tgattaacag
     2821 ttggtgaatt atctaaatca ttagtgattg cattagaaga ctcttttgta gccatcggtg
     2881 aagaactagt aacaacttca tccgataaaa taccttggct tcccaaaatt gaaattgcca
     2941 atagtaccga gcaagtcccc acctttaatt tacgaatact gaatacctca ttaggaacaa
     3001 aatatttcat cagaacctcc aattttttta ctatttttaa caattgatta ttacttttct
     3061 taaaatagat agaatgacac cgctgtcatt atctttatca tatattttcc aaattgaatt
     3121 gtcaaggaat aacacaagaa aatattaaaa tttatactct tcggaaatct cttcaaacta
     3181 ggtcagtgcc gccttgccct aagtctaggt tactgacttg gtcagttcta tagtagactg
     3241 aaactataat agtacacctc tacttctaaa acattgttag aaatcgattt gactgtcccg
     3301 atcgatttgt cctattctta tttcatttta ttatatctac aacctcaaag cagggttttg
     3361 agctatctat ggccaacttc ctagtttgct ctttagcctt ccattcaaaa gtgatgctat
     3421 ctttcttagc ttgaatataa aatatcccat ttactatatt taaatttgtt gatatgttgt
     3481 aaattataaa tgaaagaaca aatatcttgt catacaagca ttcgccaggg atatttacat
     3541 gaatatcgct catatggcgg attgaaacta aaacactaca atatatttct taaatagacc
     3601 ttctataaaa gctagattta acctcgataa aaatagatgc agtgcttcta aaatactgga
     3661 atagggcata taggtaatcg tagacaagtg ttttatagat tgtctcgcgg gagatctaat
     3721 gatgtatagc aagcatcact aaacatatag aatatttgtg ttattataat gtcaatatgc
     3781 tataaattct atcatgcaaa agaatgacta gaacatgaaa gacaggcaca aaactttgaa
     3841 caatattctg aaaacaaaaa aagacgcgag tttccacaat ctcactcatg gaaactcacg
     3901 tctttcaaaa aatagggtga attaaaaact agaacaagac actagatttt ctaaatgatg
     3961 tctagtaagg attctaaatg ctacaccaaa ttgctcacat cttatttcaa accacgggac
     4021 tcccacaaga aaggaaaatc ctataaaaat tctctctctg aggagagaga ggcctcaact
     4081 acaggtgtaa actattatca attgaaaaca acagttttta cactcaatta gactttttag
     4141 ggacaggatc actttcgctt gactgtagtt tgtcattttt ttgataaagt tagcactttt
     4201 tcagaaactg ttttgaaagt ctcaatgata tagtctactt cttcatcgct taatttagta
     4261 tgaagaggga gggtaatttc attctcaaag aaggcatagg ccttaggata gttcgtcata
     4321 tcaaatccaa gattcttata ggctgtcaag agaggaagcg gtttgtagtg aacattactt
     4381 gcaattcctg ctttagccaa ttcttggatg atgaggttgc gttcttctag gcttgctcct
     4441 tctacacggg tgatgtagag gtggcgtgaa gattcgacag tttcagtctt gtgtgccaaa
     4501 ggatggatgc gagaacctgc aaaaccacta tcatagcggt ccacaatgtc cttacggcgt
     4561 tgcaacaaac ttggatagcg gtccaattgt accaaaccaa gtgaagccat gatatcggtc
     4621 atgttgcact tataggctgg tgtaacgata tcgtattccc atgaccccag ttgcatcttg
     4681 gcaagagcat ccttagtttg cccgtgaagg gaaaggattt ggaattcctt gtacatctct
     4741 tcgtcatcaa tcactggatt ggctttccaa gtcgcacttc caccttctgc cgttgtaaag
     4801 ttcttaacgg catggaatga gaaggaagta aagtcagcga tagaaccaga aggttgtcct
     4861 ttataagtag atcccaaagc gtgggcacta tcagagacaa tgacaatacg gttaaaggcc
     4921 ttttgccact tgcttgaagc ggtaaagaag tcacgttttt tctccacgac ttggaacaaa
     4981 cggtcataat cgcaaacaat ccctgcgagc tctactggga taatcacctt agttttctca
     5041 gtgatagctt gctcaagcag gtcatagtcc atctcaaacg tatctgcttg gatatccacc
     5101 atgacagggg ttgctcccac gtgcgtaatg acactacatg aagccgtata ggttatggct
     5161 ggaacgatga cttcatcacc aggtcccact tcaaaaacgc gtaaaatcaa ctccagagcg
     5221 gctgtcgcag agttgagaca aacagtctta ggtgtctgtg tgtaaagaga caagcggcgc
     5281 tccagttctt ttgttttagg acctgttgtg atccaaccag aacgcagggt atccgctact
     5341 tcagcaattt ctgcttctgt gatatcaggc ggtgaaaatg gaatattgta atttggcatt
     5401 gatttgctcc ttttatctgt actcattctc ttatgactac tttattttag taccttaaac
     5461 acggtttgaa acatgatttt gatgtcccca aagaaactaa actctcggag ataggcgagg
     5521 ttatagcgca tcttttcagg aagaacatgc tccacatagg cctgatcaac tgacagacct
     5581 ttctctgtca tttgactgat gatggtgtcc tcatccttgt agttgatgct ggctggagag
     5641 gtaattcctg cttgcaagag caaggttgcc atcatttcag tgctatactg ctctgtataa
     5701 cgtggcactt caggtcgtgt accgacaaag gacatctcac ctttaaggac attgaccaac
     5761 tgaggcagtt cgtccaaacg gacacgtcgg atgaaatttc caaccttggt aatacggcta
     5821 tcgttagcag aagtcaccag atttcctttt ttatccgcat ccgtcaccat ggtacggaac
     5881 ttccaaatct tgaaccgacg gttgtactgg gtcacacgct cttgcttgta aatcactggc
     5941 cccttgctat ccaacttgat ccaaatgctc aagatgagaa agatgggaga ggtcagaacc
     6001 agtaagacca aggccaaaac ccagtccaag caacgcttga aaatcagcga acccttcctt
     6061 ttagagacaa gctggtagta agactcaacc tcgcttgatt tcatttccac aggcaagtct
     6121 tcccatttca gcatgctgtt ctcctttgtt tttattatac tatttgtcaa cactttttgt
     6181 caacactttt cattatacca caaaatggaa aaggcggtga aaaaaatctg taatttgaag
     6241 gatttccttc tagtactcaa tgaaaatcaa agtacagctt tgagattgca gataaagctg
     6301 acatggttta aagagatttt caaagagtat aggccatggc ccctgcctgc aaactataca
     6361 tcttgtgata ggttcctccc agagccaaga gttcctcatg ggttccactc tcgataatgc
     6421 gtcccttatc caagacatag atgcagttgg cgtcttgaat agtagaaagg cggtgagcta
     6481 tagcaatagt tgttcggccc tgtctcatct tcgccagaga agcttgaacc aagctttctg
     6541 tttcagagtc aatattggct gtcgcttcat ccaaaatcag gattttaggc tggctggcga
     6601 ctgttctagc aaaggcaaga agctggcgtt gcccagtaga gaagctcgaa ccacgctcgg
     6661 aaacagggga gtcgtacccc tgaggaagtt cttgaataaa ggaatctgca tccacaaagg
     6721 ctgccgcagc ctgaacctgc tcatcactga tttcttggta catggcgata ttggacttaa
     6781 tagttccatg atagaggaag ggttcctgca agaccaaacc gatgtttttt ctcagctctt
     6841 cttgactgaa atccctgata tccacatcat ccaagagaac tctccctgac tggaattcat
     6901 aaaagcgcat gaggacattg ataatagacg atttccctga acctgtatga cctacaaagg
     6961 caatggtttc acccttatta acagagaaag aaatgtcatc cagaatcgga tgtttaccgt
     7021 catatgagaa acacacatgt tcaaagcgga tattgccttc ttggactttg gcttgcccat
     7081 tttcttgaag aggttcatag gtcctctcgt ctaccagggc aaagacacga cctgcagaaa
     7141 ccatagacgt ttgcagtgtt gaaaagtttt gcgtcacctc aatcaaaggg tcaaagaggc
     7201 ggttgatgta ctggataaaa gcatacatgg tcccggccgt tatcccgata gaaagaccac
     7261 gatagccaaa ataggccatc aagacagcat aacctagaag tttcaacaaa ctcatggcag
     7321 gtctcaaaaa gagggcatcc aaggctacag aacggttggc atagaccaag tgctcttggt
     7381 tgatttcatc aaattctgcc tgcaggcgct tctcttgatt aaaggcctgg attattctga
     7441 ttccctcgat gttttcagcc agcttgctat tgatatctga caagagactt ctggttttct
     7501 caatgatttt cactgatttt ttccgataga gattgaccaa aaggaaaatc aaggggagaa
     7561 agagcaagac taatgctgtc aaacgaaaat ccaataccaa catggtataa agggttgtca
     7621 gaaagatgaa aactgctgag ataaagctag ataaaatccc agaaaacata tcactaatcg
     7681 tctcggtatc gttggtcaaa cgagaaacga tagaacctgc tggcgtcttg tcaaagtaag
     7741 acatgcccag tttctccata ttggcaaagg catcccgacg aatatcccta acaatactgt
     7801 aagacacgcg cgcaaagaga agattgccga catactgaac tacagtttgt aggatgtaga
     7861 gaccatagta gaccagcaaa acggtaacgg ctagttggtt aagattgctg agatactggt
     7921 cgataaagtg ggaagccacg aggggtatga cacttttaat gaccgtcgtc gctaggagaa
     7981 aactgagtgc caaaaaggtc aggagtctat aaggcttgag ataagacatc aagcgcttca
     8041 atacagccca ttgttcttgt ttattctgca tcttcttctc ctttcatttc taactgctga
     8101 gactggtagg tttgggcata ccagccatcc atcgctagca agtcttcgtg cctgcctcgt
     8161 tcgataattt gaccattttg tagaactaaa ataaaatctg catggacaac agcactgagg
     8221 cgatgggcag ttataatggt tgtcttgtcc tttcgcgtct ccttgagatt gtcgataatc
     8281 gcatactctg tcttggcatc tacggcggat aaggaatcat ccaaaatcaa gatatcaggg
     8341 tttaaaatca tagcccgact catagccaac cgttgctttt gaccaccaga aagactgact
     8401 cctttttcac caatcagcgt atcaaatcct tgaggcatgt ctacaatatc ttggtaaact
     8461 cgggctagct tagtagcttc ctcaacctct gaaaggggca agttaggatt gccaaagcgg
     8521 atattgtcta ggattgaagt cgcaaagaga aactggtcct gaggaacata gcccatgaga
     8581 ctgcgaagtt ctgtcaaacg atagtcccga atatcgtgac cgtttagata aatggcaccc
     8641 ttatccacat cgtattcacg caagaggagc ttgattaagg acgttttccc agagcctgtc
     8701 tgcccaacca agcccagtgt ttgccctttt gccaaactaa agtgaatatc cgtcagtgtt
     8761 tcctcatttt caaaagcaaa gctgtcaatg gcatactcca aacgcccatt ttcaatacca
     8821 tccagaggaa actcagggtc ttgtacagga gattcctgag acaaaagatt ttcaatccgc
     8881 tggtaagaaa ccttccctcg ctgagtagta ttaaagagga agccgatggc cataagaggc
     8941 cagaccagca tatccaaata gctgataaag gtgactagat taccaactgt aatctgccct
     9001 tcctgaacca tcaaggagcc aaccaaaagc gttaaaacat aggacgaacc aacaaacaag
     9061 agaaccatag ggtcaaagag actatcatat ttcatggttt gcaggttctt ttggaaggtt
     9121 aattcattga ctgcctgaaa agacttcaac tcgtctgcct gataaccgaa agacttggtc
     9181 actttgatac ctgatacgga ctcctgtacc ttgttattga gttcagaaaa agcagcttgg
     9241 gattcgccaa aggccttatg agtctttctc cctaggcgac tagtcgcata ggccatgaaa
     9301 ggtaggggga gaatggcaac aagagtcatc tgccatgaga tgctaaagag catggtcaac
     9361 aaagtcacca gagccgtgat agaggcatcc accgcagaca tgacaccgcc acctgctaaa
     9421 cgagtcaagg cattgatatc attggttgcg tgtgccatca gatcacccgt ccgataggtt
     9481 tgataaaagg ctggcgacat ttttgtgaaa tgcttaaaca agcgagaccg catgatctgt
     9541 cccaagcaat aagaggtccc aaggatatac atacgccaca catagcgcaa atagtacata
     9601 ccaaaggctg caagtagcaa gtaaaatagg ctaagaagga ggtcctgctg ggttaattgc
     9661 cccgatgtga tggcatcaat gactcgcccc ataaccatag gaggaatgag attgagaacg
     9721 gaaaccaaga ccagggccac aatcccgact agataacggt gtttttctaa cttgaaaaac
     9781 caccagagtt tttgaataat ggacataaaa tccctttctg attgcaaatg gaaacctgag
     9841 gccaatactc aatgaaaatc aaagagcaaa ctaggaaact agccgcaggc tgctcaaagc
     9901 actgctttga ggttgtagat agaactgacg aagtcagtaa cctacatacg gcaaggcgac
     9961 gttgacgcgg tttgaagaga ttttcgaaga gtacaagacc ccaggttttt cttattcata
    10021 agttacgact gtaacagcac ccttgtcata ttcagcaata aagatattgg ctacattgtc
    10081 atgcccttgt ttgctgaggt tatcaagcaa ccactcttcg ctacgaccaa tcgattccaa
    10141 gacgtctact tgaatcacac cgtcagtcac aactggatac ttaggatttt catctcccat
    10201 ttgcacaacg atgagttgcc cattttgctc ttgcacagct cgtttgactt gcttcatctg
    10261 gaaaatccct tggctacgaa gtttgagggc tacatccgat gcagacaaac caactgaacg
    10321 acaggcttat gggtcaatat tcccattttt gataaggaga gttggcttac catcaatcaa
    10381 acgtttcaca aagtgaacat tgttgttgag ctatttgaga gtcaagatca gtttgattaa
    10441 aatttcgata taattaagtg tcatttgttc acatccacca gttcaattgc gtctgtctta
    10501 tacaattcga ctttctctaa caggtacttg tctggctcac ttccgtttag ggcacgataa
    10561 tagcgatctc ccaccttgat aagtgcgcca tctgtgtttg tggaagtatt aacatggact
    10621 tctgacttgt ctactcccaa atctttggaa acaacctcga tgaaatgaag tgaagtttga
    10681 aatttattgt tagaaacttg attgttttga taagtcgtga tgctgaccaa aagcatagct
    10741 aaataaggcc agagctgaaa tcatgaccaa ctcacgaaat ttggttcctt ttttatcatg
    10801 gtatgccttg aaagcaaaaa aaactgtcac agctaataga acaatcccaa agccaaccat
    10861 gataccattt tgctgaccga tttggctgag tacatagtca taagagtaga atttcatgta
    10921 ttttcactcc ctttcataaa atcattctta attataaacg aaagagagta atttttcaaa
    10981 ccatacgttg gggaaataga tctttttttg gtataataaa atctataatc tgaatgaaaa
    11041 aggtaacttt atgaaactta tctcatggaa tattgattcc ctaaacgctg ccctaactag
    11101 tgactcagct cgtgccaaat tgtcccaaga agtcctacaa accttggtcg ctgaaaatgc
    11161 tgatatcatt gctatccaag aaaccaagct ttctgccaaa ggacctacaa agaaacacgt
    11221 ggaaatttta gaagaactct tcccaggcta cgaaaacacg tggcgctctt cccaagagcc
    11281 tgcccgtaaa ggctatgctg gaaccatgtt cctttataag aaagaactta cacccactat
    11341 cagcttccca gaaatcggtg ccccttctac catggacttg gaaggccgta tcatcactct
    11401 agaatttgat gcatttttcg taacccaagt ttacactcca aacgctggtg acggtctcaa
    11461 acgcttggaa gaacgccaag tctgggatgt caaatatgcg gagtatttgg ctgaactaga
    11521 caaagaaaaa ccagtccttg cgaccggtga ctacaacgta gcccacaatg aaatcgacct
    11581 tgcaaatcct gctagcaacc gccgttcacc tggatttact gacgaggaac gtgctggatt
    11641 taccaaccta ttggcaactg gatttactga taccttccgc catgttcatg gcgatgttcc
    11701 tgaacgctac acttggtggg cacaacgcag caaaacttct aaaatcaaca atacaggctg
    11761 gagaatcgac tactggctca caagtaaccg tatcgctgac aaggtcacta aatctgatat
    11821 gattgactca ggtgctcgcc aagaccatac accgattgtc ttggaaattg acttgtaagg
    11881 attttctata tggactacaa tgcggtcatt cccgagtttc ttgtatcgaa tatcgaacag
    11941 tcccggtcct tctactgtgg tttactgggt tttaggattg aataccaacg ttcagaagaa
    12001 aactttctct ttctcttgaa gagtgtcaac taatgttaga ggagggaaca aaggatcaac
    12061 tagctgaact gacctacccc tttggtcgtg gagtcaatct ctcctttggc ataaaggatg
    12121 ttccaaaact ctatcaaaaa gtgatggagg caaactatcc tatttatcgt cccttgacca
    12181 aaagaaagtt tcgtgtcagt gatccctata tctatcctca taaatttgca gttttggatc
    12241 cagatggcta ttttttaaga tttagcgagt agaataataa aaattgggaa aagtctttaa
    12301 aagttagaaa aaggcatatt gtcaggtgtc taaaaacttg atagtatgcc ttttatgatg
    12361 gaaaaatctt ctaatactct tcgaaaatct cttcaagcca cgtcaacgtc gccttaccgt
    12421 aggtatataa tactgactct gtcaattcta tccacaacct caaaacagtg ttttgaggtt
    12481 gtggatagct tcctagtttg ctctttgatt ttcatttagt ataaatgtta gcttacaatg
    12541 gagtttttgt tcaccctctc ttctgtttgt tcgtttttta aaccaaaaca ctaacaaaat
    12601 agttgatttc taaagttatt tagtgtaaaa taaaaacatt ggctcaagcc tatttaaaat
    12661 tgaatatcgt tttacttgtt tatgtcgtga attggcacga cgtttctaca aggtgccgga
    12721 acacctaaca ataagtaagt cagcagtgag atatggccgt ttttgccatg cctatttggg
    12781 ggacttactt agagattaag taggtctttt ttgaatattt ttaatatttc ccttaattag
    12841 tgcggacggg aggtgaaatt atcctgtgaa taatttcagg aatccaggga atttcatccc
    12901 taatttttga gcccctagct ctttcatttc taggcttagg ctaaaatagt tccccgaact
    12961 attttactct caaaaatccc gtcatagaca ataacaagat tattgtctat gataccacta
    13021 caacgggaaa tatttgataa gactcgcttc gctcgtaata gttttatcaa atatatagca
    13081 ttagcaaaag ggatcactat agaaacattt aaacaacaag taaattaact tttagacttt
    13141 aggaggtctt atgaaattat tagaagagcg catcctcaag gatgggcata tcttgggtga
    13201 taacatcctc aaggtagatt cctttttaac ccaccaagtt gactttagct tgatgcgaga
    13261 gattggtaag gtttttgcgg aaaaatttgc tgctgccggc attaccaagg tcgtaaccat
    13321 tgaagcgtcg ggtattgccc cagccgtttt tacagctgaa gccttaaacg ttcccatgat
    13381 tttcgccaaa aaagctaaga acatcaccat gaacgaaggc atcttaactg ctcaagtcta
    13441 ctcctttacc aagcaggtga ccagcaccgt ttctatcgct ggaaaattcc tctcaccaga
    13501 ggacaaggtt ttgattatcg acgatttcct tgctaatggc caagctgcta aaggcttgat
    13561 tcaaatcatc gaacaggccg gtgccacagt ccaagctatc ggtatcgtga ttgagaaatc
    13621 cttccaagat ggccgtgatt tgcttgaaaa agcaggctac cctgtcctat cacttgctcg
    13681 tttggatcgt tttgaaaatg gtcaggtcgt atttaaggag gcagatctct aatgcaaact
    13741 caagaaaaac actcgcaagc agccgttctt ggcttgcagc acttactagc catgtactca
    13801 ggatctatcc tggttcccat catgattgcg acagcccttg gctattcagc tgagcagttg
    13861 acctacctga tttctacaga tatcttcatg tgtggggtgg caaccttcct ccaactccaa
    13921 ctcaacaaat actttgggat tggactccca gtcgttcttg gagttgcatt ccagtcggtc
    13981 gctcccttga ttatgattgg gcaaagccat ggtagtggcg ctatgtttgg tgcccttatc
    14041 gcatctggga tttacgtggt tcttgtttca ggcatcttct caaaagtggc caatctcttc
    14101 ccctctatcg taacaggatc tgttattacc acgattggtt taaccttgat ccctgtcgct
    14161 attggaaata tgggaaataa cgttccagag ccaactggtc aaagtctctt gctttcagct
    14221 attactgttc tgattatcct cttgatcaac atctttacca aaggatttat caagtctatc
    14281 tctattttga ttggtctggt tgttggaact gccattgctg ctactatggg cttggtggac
    14341 ttctctcctg ttgcggtagc tccacttgtc catgtcccaa ctccactcta ctttgggatg
    14401 ccaacctttg aaatctcatc tattgtcatg atgtgtatca tcgcaacggt gtctatggtt
    14461 gagtcaactg gtgtttatct agccttgtct gatatcacaa aagatccaat cgacagcacg
    14521 cgccttcgca acggttaccg cgcagaaggt ttggccgtac ttctcggagg aatctttaac
    14581 accttccctt acaccggatt ttcacaaaac gttggtttgg ttaaattgtc aggcatcaaa
    14641 aaacgcctgc caatctacta cgcagctggt ttcctggttc tccttggact gcttcctaag
    14701 tttggtgccc ttgcccaaat cattccaagc tccgtcctcg gcggtgccat gctggtgatg
    14761 tttggttttg tatctattca agggatgcaa atcctagccc gagttgactt tgctaacaat
    14821 gaacacaact tccttatcgc agctgtttca atcgctgcag gtgtcggtct caacaacagt
    14881 aatctctttg tcagcatgcc gacagccttc caaatgttct tctcaaacgg aatcgtcgta
    14941 gccagcctac tcgccattgt cctcaatgcc gtattaaatc ataaaaagaa ataagaaaaa
    15001 gaggtgcgag cctctttttt gtttatcaca aattgattat aaatacaatc aatcccaatt
    15061 cccatctaat tgaattggac ctatttcaaa ttctttaaaa tattatgttc caaatcgtta
    15121 atattatata agaatggtaa aatatcaaat gtttctcgta aattattctt agccttatac
    15181 caaccttgtc catcagtaat ccacataaac tcaacattag gaatagcttt aatttcttca
    15241 gcaatcattt tgtaagatct agccgtctca tttaattttg aaccacttcc tgaataaaaa
    15301 ttaacctcaa tcagataaag cacttgttca ttttttatga caaaatcaaa acgtttcaca
    15361 gtattcccat cattcgtaat agcagataaa tcgacagaaa aaatttcctc tatttcattt
    15421 tgttcaatct ctttaaataa attctctcct aaaatatacc cttcagcttc aagataactt
    15481 tgaacaatat tttccatcgc atctccagtc cgatttttgc gcccattagt atccatacca
    15541 acctcaacac ctgtaacgta gtcaactaaa tttgatacta aatgattttg caataaatca
    15601 aatatacctg atttttccaa aaacatagta tattcttcaa tactatagtt tcgtttacta
    15661 aaatcaaaat agaaatcttt tatcggatcc ttaacaataa tcgtatctct caaacgttta
    15721 gcaataagta gaggcacaac tttcaaaatt tctggataat tttgatataa gtctaaaaaa
    15781 tcctcttgta tatttttact accaataaga ctattcataa tatttagagc aacttttata
    15841 ctagatacat ttttataaac cttgggaaaa tctgtataat aagtccagtc agctactgtg
    15901 tcggtcatcg ttgacaacca ctcatcaaaa tttctagttt gtttcatttt ctgcctccaa
    15961 cctcttcctt gcaattttta aatattcttt ttcagcatcg atacctataa atcttctacc
    16021 taaccgcttc gcaacaacac ccgtagtgcc actaccaaca aatgggtcta gaatatagtc
    16081 accctcttta gtagaggcta aaataatgcg ttctaacaaa tactctggtt tttgagttgg
    16141 atgtttccca gcccattttt caactttctt tgttaaagaa cccgtccaga catctttcat
    16201 ttgttttcca tcattcaatt ctttcattaa atcataattg tagtaatgac gagctttttt
    16261 atcatttttt ctggcccata aaatggtttc agtagaatgg gtaaaataac gacaagataa
    16321 attgggggca gggtttgttt tctgccaagt aatattattc agaattttaa aaccttcttg
    16381 ttctaatgcc attccaactg agtatatgtt gtgcaaacta cctgaaatcc ataccgtccc
    16441 attaggcttc agaacttctt ttgctaggcg aatccattta cgattaaact catgtttttc
    16501 ttcgaatgaa gaaattttat cccaatctcc tttatcaaca gaaacaactt gtcccccaga
    16561 attagatatt ccaccattac ttaaaaaata aggtggatca gcaaaaatca tatccatact
    16621 ttctggtttc atttttgata agaacttgaa cgtatctgaa tgaacaagaa tcatcttatt
    16681 tttattgtag tatggttttg tcataagaac acctccatac ttatattcgt tatttttcat
    16741 aatttgtgac tataatttca gaaatttttc ctcgacttga agattttgct ccattagttc
    16801 gggtagcttc aacataatgt atattaaaat ccttatacaa ctcctctact aaagcactag
    16861 aagaatttga taacataaca taagctcctg tatcactcaa tctcttaaag gcatctctta
    16921 atcttacttg atctgcaaaa gagaatccct catgagtata agacgtaaat gcactcgtct
    16981 cagacaatgg aatatatgga gggtcaaaat acacaaaatc tcctgttcga acatctacaa
    17041 ttgccttttc aaaatctccc actttaattt ctagttgatt gttatttaga taaactgaaa
    17101 tagcagatat caattcctca tcaacaattt taggattctt ataacgtcca tatggaacat
    17161 taaattggtt cttagaattc acacgatata gaccattaaa gttcactctc aacatatata
    17221 gaatacgtgc agctctttgt acttcggaca tcatatctat tctttcatca cgatctgcag
    17281 aacgtaaatc taaataatat tcttttgaat tatattcctg atgaactttc aaaatttcaa
    17341 tcaattcttg aggattgtcc ttaatttgtt gatagcaatt tattagttca gcgttaaaat
    17401 cattaataac tgcatcttta ggagccaaat caaaaaataa agctccacct ccaacaaaag
    17461 gttcgaaata cctgttatag gttttaggca ttaattctct aataacaggc aataattgtc
    17521 ttttaccacc tgtccatttc gtgaacggtt gtaaagtaac tttctttatt tcttttatct
    17581 tcatgctttt aattatacca tagaaattaa aacacaactc ttgtattttc taccacatta
    17641 ctaaattttc tattttagaa ttaaatcata tcaatataaa aaaatgagta aggcaaatct
    17701 tataaattcc aaaattcacc tcactctatt aaattactct ttatatcctt acccgtcttt
    17761 cctcagacct ttggcctgtg acaaacatag taaaggttgc tttgcagaca tttctgccct
    17821 cttgattggt gatatccaca tccatcacac aggttgtacg accttgatgg acacattctc
    17881 ctttaatggt caatacatcg tcgagttttc ctgccttaag gtagttgata gaggattgga
    17941 gtgtcacccc atcaagtccc agcgagataa ccaccaaacc actgatttgg tcacatagtg
    18001 tgaatagata gccaccatgg gcattgccat agtagttgag cgacgagttc actactttgg
    18061 tcgtcaccac aacgtgacca tctctcattt tttcaatttc gtaattttca aaggcagata
    18121 tagcgtcaaa atgaaagtct ttcatcgttt cctcctgata tttcaaatga cactatgata
    18181 ctacttttta taggactgtg caaggagaaa gctcctagtc tagtaaaatt ccgacatgtt
    18241 ccacaaagcg cataaaggct gtctgccctt gttctgtctg cttgtagact cctgcatcct
    18301 caagtacacg cgcaaagata gcacccacag agtccttgac gattgcaagg gctttttctt
    18361 tatccgttag gtctggatgt tgggatttga gttggtctgc ccactcctga tgataatcgg
    18421 caactgtaac agcttctcct acaagatagc tagcgacttg ctctacttct tctttcagac
    18481 gtggtggcaa gattgccaag cccatgacct caatcaagcc gatattttcc ttcttgatat
    18541 gttggacatc cttgtgggga tgatagatgc catcaggatg atctgctgaa gtctgattgt
    18601 ctcgcaagac caagtccaac tcaaactgtc catcacgctt acgcgctatt ggtgtgatgg
    18661 tgtgatgcgg tgtcccgtct gtctctgcta aaatctgcac actagaatct gaatactgac
    18721 gccattcctg gaaaatctta tcagctaagt taatcaaatc ctctttggaa tccgaagtca
    18781 agcgtaggac agacattggc cacttgataa ttccagcctt gacctgctca aaaccagcaa
    18841 atcggaaggt cttttgcaag ggagccaatt ccataggaaa tacgtgacgg cctccctgat
    18901 aatgatcatg agttagaata gagcccccca caatcggcag gtcggcatta gatccagcaa
    18961 aatatcctgg aaactgctct acgatagcca acagacgttc aaaactctga cgactaatgg
    19021 ccatgggacg atgctggcca tctaaaaaga tacaatgctc attaaagtaa gcatagggcg
    19081 aatactggaa accccattcc tgaccaacca tttcaaaacg gataatccgg tggttgctgc
    19141 gagctgggtg gttgacccga ccatggtaac cctcattctc taaacaaagt tgacactgag
    19201 gataattact agcttgcacc aacttggcta ccgcaatctc tttcggatcc ttttcaggct
    19261 tagagagatt gatggtaatt tcaagttctc cataatcaga tggaacacga taaacgatat
    19321 ttttagcaat ggccttgagt ttgatgtagt catttttctg actgagttga taaaaatcct
    19381 ctatcgcttg ctcaggagag taggcatagg cttcccagaa gtcacgattg acctgactcg
    19441 gacaaggagt caccaagtcc atcaattcag taccaaggat ttcacgcgca gtctgactat
    19501 cctcaatcgt ctctaatcga acggcttcct caactagctg gtccttgagg tcaatcaatt
    19561 tatccagatt ggtctcaact tccaaaacac cttctcccac tcgtgccaaa acacgattgg
    19621 tcaggtagat tcgatccatt tcctcaaatg aactttcaga aatgacatgt gttacaaatt
    19681 tatctactaa ggtcactata gagcctcctt ttgactagtc aaggacgcga gtgccacctg
    19741 caacttcagc gatatagaag cttggagcgt atccaactac ttcctcgtag tgtttgccta
    19801 cagcttcctt aaaggcctca acagtatctt tttgaaccaa ggcaatggca cagccaccaa
    19861 aaccagcccc tgtcatacga gcaccgagaa ctccttcttg tgcccaagct gtgtgaacaa
    19921 gagtatccaa ttccaaacca gttacttcat aatcatgctc cagagaaacg tgtgacgcat
    19981 tcatcaaacg accaaatgtt tccaaatcac ctgcttgaag ggctgcttga gctttaaggg
    20041 tacgttggtt ttcaaacaca gcatggcgag cacgtttcaa acgattttca tctttaatca
    20101 gatagctata ttggtcaacg gcccactcgt ccaattcacc cagggtctga atatccaagg
    20161 caacttgcaa ttcttccact gctttttcac actcagcacg acgttcattg tatttagagt
    20221 ccgccaattc acggcgtttg ttggtgttca tgataacaac gacattgtcc ttcaaatcaa
    20281 gtggcaccaa gtcgtattct aaagtattgg tatctaagta aatagcacgt tggtcagccc
    20341 ccataccaat agcaaattgg tccatgatac cagagttgac tccgataaag ttattttctg
    20401 tttgttttcc gattttaacc aaatcgagac gctctagttt taaatcaaag agatgctctg
    20461 ccacgactcc tgtcaagagc tccaaggatg ctgaagaaga caaaccagca ccatttggga
    20521 tattcccata aacataaaaa tcaaaacctt tgtcaatcac gtgcccagct tcttgcaaga
    20581 aatgaaggac accttttgga taattggtcc agttgtgctc tttttcaaac ttgaggtcag
    20641 cgagaggcac ttcgataatg cccttgtcct caaagttagc tgagtagaaa cgcaagactt
    20701 ggtcgtcacg cttacgagct gcaccgtaag ttcccaagga aatagcagca ggaaaaacgt
    20761 gcccaccgtt gtagtctgtg tgttcaccaa tcaaattaat gcggcctggt gaaaagaagg
    20821 tttggtctgc ttcttgacca aaaacagcaa gaaagtcttt gcgaagggct tcagtagtaa
    20881 gatgttgtgc catatgaatt ctcctttgac tgtccgttaa gccaccttaa cgtataatcg
    20941 ttttctttct attgtatcca aggaattttc caagatcaat cctttttact aaaattttag
    21001 taaaatatca gtaaaaagaa gaaaaacatg atatactaac ctaatcaagg aggatttatg
    21061 gctaccttaa aagacattgc acagctagcc tctgtctcta tcgcgaccgt atcccgcgtc
    21121 ctcaatcgcg accagagcct atctgttaca gaagaaacca gacaccgtat tttaaccgtt
    21181 gctgaagagc tgggctacac caagcacctc aagacaggcg agtcccacaa acccaagcaa
    21241 aagattgcca ttatccaatg ggtcagcgaa caaggggagc tggacgacct ctactactac
    21301 cagattcgcc taggaataga aaaaagagcc caagagttgg actatgatat cttgcgctat
    21361 tttaatgacc atccttttac cttaagcgag gaagtgattg ggattctctg cattggaaaa
    21421 tttagccgag ctcagatttc tgcctttgaa gaataccaaa aacccctggt ctttctagac
    21481 agtgatacac tttctctggg gcatacttgt attattacgg atttttacac tgccatgaaa
    21541 caggttgtcg attatttcct cagccaagga atggaccgta tcgggattct aacaggcctt
    21601 gaagaaacaa ctgaccaaga agaaatcatt caggataagc ggctggaaaa tttcagaaac
    21661 tacagtcaag caaaaggaat ctatcatgat gaactggtct ttcaaggaaa ctttactgcc
    21721 cagtctggct atgacttgat gaaggaagcc attcagaact tgggagacca actcccacca
    21781 gcatttttcg cagccagcga tagtttagct atcggtgccc ttcgtgccct ccaagaagct
    21841 ggaatcagcc taccagaccg tgtcagcctc atttccttta acgacaccag cctgaccaag
    21901 caggtttatc ctcccctctc cagcatcaca gtttatactg aagaaatggg gcgagcaggt
    21961 atggatattc ttaacaagga agtcctccac gatcgcaaaa ttcctagcct gaccatgctg
    22021 ggaaccagac tgacattaag agaaagtacc ctaaatcaag aataggataa cataaaaaac
    22081 gaatagagtt ctaaaactcc tattcgtttt ttattcgatt acaatcatag acttaatggt
    22141 cttacgttca tccatatctt tgtaggcttg gtcgatatct tccagtttat aacttgaagt
    22201 aaagacgcga cctggattga tatcaccatc aaggacggct tttagtaaaa attgcttatc
    22261 gtatgttgta gcagaagctg ccccacctgc tacagagata ttttgcataa atgtcgaacc
    22321 aagagcacga ttattatagt gtgggactcc tacaaagccc atacgccctc cattatgaag
    22381 aacacctagc gcctgttcta tagcagcctc cgtaccaaca cattcaagtg ctgcgtctgc
    22441 tcctccaccg aggatttcac gcaccttggt aattccttct tgaccacgtt ctgcaacaac
    22501 agctgtcgca cctgactcca tagccatctt ttgacggtct tcatgacggc tcataaggat
    22561 aatttgtgat gctccacgca tcttagccgc gatgacagca cattgaccaa cagccccatc
    22621 accgataaca acaaccttgt cccctttttg aacatttgca acacgcgccg catgatagcc
    22681 tgtcggcatg acatctgcaa gagtcaaaag ggactggagc atcccttctg tatagtcaga
    22741 aggttgacca gggattttaa ccagcgccca gtttgcatag tggaagcgaa tatattctgc
    22801 ctgaaaatca ccccccaaat tattgccaat atgattgtcg caagaaccgt caaatccagc
    22861 aagacaggca tcacactcac cacatccatg tgtaaaaggg acaatcacaa aatcacctgg
    22921 tttcaccgtc gtaatggctt ccacagcttc ttcaacaatc ccaatcgctt cgtgtccact
    22981 atttttgtgt ccagctttcg tttctggatt acggtacctc cataaatctg aaccacaaac
    23041 gcacgcacga accacacgaa taatcacatc atccgcttct attatttgcg gacgttcaat
    23101 gctagcaagt ccaacctgac ctgcctttgt atatactgct gatttcattt aaaattttcc
    23161 ttccttataa agtttaattt tgagatttaa acgatttaaa gctgtctgta gctgagacaa
    23221 gcgctcctct aatttttgct tttcctcttc taaaatacca agcctctcct ctctcgtttc
    23281 atctcccttt tggtagagcg acatatagtc aactaaacta tctacagaga cacccgccga
    23341 acgaaaacac ttaataaatt ccagcgcttc gatatcctga tcttgaaaat cacgaatccc
    23401 agtagcagta cgagtaatcg gtggcacaag accaacccgt tcataatacc gaatcgtatc
    23461 cgctgaaatt cccaacaaat cactggcaga tttaatattc acacgctaac ctcctctcat
    23521 ttcattcact gaattcacgc tattctaact cacttatctt attatataac tttgagttga
    23581 ctccaagtca agcattttgt atctaatcga aaaattttta tcattaacaa tcatatatct
    23641 ggagtttata caatgctctt ctcttaccaa tttttgaaat atttaaataa taaagaaatt
    23701 actctattcc aaataagata gtacccaagt atttttcact tttttctaat gttgatgctc
    23761 ataactccgt tccaagtcac acacctttcg cttatgggtt tggtgagttt ctaggtcagc
    23821 atcaatttca atggtaatat tttgaaaacc acaatctttt aggaaaattc gaatagactc
    23881 tttacaagtt tccatatgtt ccatttcttt tagacaaaca tggacaatgg catttttttc
    23941 caaagcatcc atagtccaga gattaagctg attaaggctg gccacattgt ccaatcgctc
    24001 caggccactc tttacttgct tgatatcaag accttctggc acagcatcca agaaaatctt
    24061 gagtgtagac caaaaacgtg gaagggcttt tgaaagaata aagaaagaaa tgacaaggga
    24121 caaaagagga tctaggatat accagtccgt aaatcgaaga acaatcgcca tcaggataac
    24181 agctacccac cctagcgtat cttccagaaa atgcagactc agaatagact cattctttgt
    24241 ctttccctta ccaaccacca gactcgctaa cagattgata gtaatcgcaa taattcctaa
    24301 ccagagaatc ccctcatcat tgactggttg cggatgcaaa atcttcgtga cattttccaa
    24361 aatgactaga acagagcccg ttacgagaat cacagctgtt accaaggctc ctagcaggct
    24421 aaaccgctta tagcccaagg tgtactgatt gtcttcttca cgattggaga ttgtttctag
    24481 aaaagctgat attccaattg caatcgcatc tcccaagtca tgcacagagt cagcaagaac
    24541 agcgctagaa ccaaatactc cacctgcaat aaactcaaca atggcataag tcaaatttaa
    24601 gaaaaaagcc acccaaacag catattttgc cttcatattt ctcattcctt tgttataata
    24661 gatttatgaa caccttgttc attatcatta tccactaaaa ctcaaagaaa ggatagaagc
    24721 aaaacgtcag ctttattcag ttctgaacaa tttgccttaa gtgtccatat gactaacatt
    24781 gaccgccgta tcagcaaaac caaaaaagcc atctatcaag cttttataca acttttgaat
    24841 gctaagggct acgaggccac tactgttcag gatatcattg atctcgcaga tgtgggacga
    24901 tccacctttt actgtcacta tgagagtaag gagcttcttc tggaccagct ctgccgctac
    24961 ctcttccatc atctttttga aagagagcaa gccatttcaa ccgaggacta cctcgcccac
    25021 ctctttctcc attttcataa aaaccaagac catatcacca gtctgctatt ttccaaaaat
    25081 gactacttcc tccgtcaact ccataaagag ctagaacacc atgtctattc cgtgctagct
    25141 gataatttaa aagaagccca ccctaatctg cctacttctt acctccaaca cttggtcatg
    25201 tccaacttta tcgagacatt gacctggtgg ctcaaaaaag gtcaagattt cacagaccag
    25261 gaagttgtcc aattttatct agaccttctc attcctaaaa attgaatata gagtaaagct
    25321 tcagttgtct tatttctagg ttactgagtt ttttatcttt tcaacaacaa aagaggaccc
    25381 gccgatcctc tttttcatac tataaatcct tgattatcaa ctatatctgt tttaatcgaa
    25441 atctcaaaac agcactttca aacatctttt cctagttaag taaatcagta ttctgcttag
    25501 ctgccttgct ccattgatac caaccaacta gactgttaat gagataaatt agatatttcc
    25561 cttgaatttg caggctttct ccccaccaga gatagattga aaagacattg gtagccgccc
    25621 agaatatcca ctgttcacgg taaacagctg tcatgaggat ttgccctacc ccattggttg
    25681 catctgtgat tgaatcacga tagggacgat tggcaccaat agactgataa atgaagccaa
    25741 aggccaacca ccaaagcaca ctaatggaaa gatactttgt ccagcccttg ccgtccagtt
    25801 tacgcgcgac aaactcctgc ttttccttct taaactgtgc ctgataaatc caaactagaa
    25861 gtccaattgg ctgcatgact gtgaagtaaa gtgtcgtcag cacctcacca taaaagcctt
    25921 tctgtagggc caaaataagg taaataacag agttaatcaa gccaaaaaga taattacttg
    25981 ctcgaccttc cgatacaaag attacacaga taatccctgt caagctacaa atcatcccaa
    26041 tccagtcaac aatacgatgt tcgtaaacca actccagcca gagaggaaaa cttcctaaaa
    26101 ccagcaaata aatccactgg gcaaaactac gatgggcaaa gaggtcatcc cagatagcct
    26161 tcatagttcc tgaaaatcct aaatcagcca tagccgcaac catacgacgg taaccacctg
    26221 acatttcacc tagggttgtt ttgatatttt caattttctt ttgcaaataa gtatgcatca
    26281 tttctccttt tgtttttaaa gagccgtgtc tggatagact ttcggacgca acgctctatt
    26341 agataatgaa ctgcctatac acaagatttc taaccttagt cgacatgagc tgaaacctct
    26401 tatttgttaa gtagttcaca aaatattata cacctatttt atgaatagtc aactgtcttt
    26461 acagtaaaat tttagaaaat catgaaaatt ttctctttct ttccatttta agtgacattc
    26521 agtcattctc acatcaaaaa agcccagacg aaattgtctg agcattcttt tatctagtcg
    26581 tttaaggaag ttgagttcag tatgtttaaa gtctctgtcc catcatttct tcaacaaacc
    26641 ttgttcttgg agaaactcct tggctacttg ctttgctgac ttgccttcaa caccgacttg
    26701 gtagttgagc tggctcatct ggctttctgt aatcttacca gccaatgtat taagaactct
    26761 ttccaactct gggtgtttct tgagaagagc ttctttcatg agtggagccc cttgataagg
    26821 tgggaagagt tgcttgtcat cttccaagac ctgtaaatca taacgctcca attccgcatc
    26881 agtcgaatag gcatccgtga tttgaatatc ccctgactga atagcctgat agcgaagggc
    26941 tggctccatg gtcgctacat tgagattgag accatacatt gattgcaagc ccttatttcc
    27001 atcttcacgg tcgttaaact cgagtgtaaa acctgccttc aactgccctt ccactttttt
    27061 caagtctgaa atggtcttca agccatattc ttgagcaatc tttttcggaa cagctacagc
    27121 ataggtgttt tgataagaca tgggtttgag ataggctaga tgatcctgct tagcaatgcc
    27181 atcacgcgcc acctgataaa cctgttctgg ttcatgactc accttgggtg atggttgaag
    27241 caaactttca gtcaccgtac cagtaaattc aggatagatg tcaatatcgc cttttttcag
    27301 agcttcataa aggaagcttg tcttcccaaa attcggttta acagtcgcag tcatgctggt
    27361 attttcttca atcagcaact tatacatatt ggccaaaatt tctggttctg gacctatttt
    27421 cccagcaata accaagtttt ccttctcttt ttgaaccaaa agagctggac tataagacag
    27481 acccagtaat aaagccacca aggcaaaacc tgagaaaatc gtccgtaatt ttgctttttc
    27541 catcactttt agtaggaagt taaaggcaat ggctagcact gcagaagaaa gtgccccaat
    27601 caaaatcaaa ctggcattat tacggtcaat tcccaaaaga ataaaggaac ctagtccccc
    27661 tgcaccaatc aaggccgcca aggttgccgt accgataatc aaaacagctg ccgtccgaat
    27721 cccagacatg ataacaggca tggcgagtgg aatttcaaat ttcttgagac gttcccatct
    27781 ggtcatccca aaggcaatcc cagcctcttg caggttcgga tcaattccct tcagcccagt
    27841 gatagtattt tgcaaaatag ggaaaatcgc ataaatcact agagctgtca aagccggcaa
    27901 ggtcccaatt cccatcaaag ggataaagag ccccaacaag gccagagacg ggatggtctg
    27961 gaaaatacct gcaatctgca agacccagtc ggccagcttc tcatgatagc gaagaaaaac
    28021 agccaaggga atcgcaagca aaatagctag taacaaggtc aaaagcgaca actgcaaatg
    28081 ttgagataga gctgtcaacc aatcactaaa acgatcctga aaagttgcaa ttaaattagt
    28141 catgaacact acctccaaac aagtctgcta caaagtctgt tgcaggcgct tttaaaattg
    28201 tctcgggatt cgctacctgg cgaatttctc catcctgcaa gacagcaata cggtccgcca
    28261 acttcaaggc ttcatccgta tcatgggtta caaaaatcgt tgtcatccca aactctttat
    28321 gcaattcttt tgtcagaacc tgcaactgtt ttctcgaaat agcatccaag gccgaaaagg
    28381 gttcatccat gaggaaaatc ttgggctgac caatcatagc tcggacaata ccgacccgtt
    28441 gctgttctcc accagataat tcactaggta agcgatgccc atactcggct actggtaaac
    28501 caaccttagc caaaagctct tctgttttct tcgtaatttc ttccttgctc caccccttca
    28561 tttcaggaat gagagcaata ttttccgcaa ctgttagatt tggaaaaaga gcaatagcct
    28621 gtaaaacata accagtagaa agacgaagtt cacgctcatc atagtctttg atgcgcttcc
    28681 catccatata aatatttcca tcagttggtt ccaaaagacg gttaatcatc ttgagcatgg
    28741 tcgtcttacc tgacccagaa ggccctacta aaaccataaa ttccccatcc tcaatctgta
    28801 agttgacatc tctcaagaca tccttttctg tgtagcgcag tgctacattt ttgtattcaa
    28861 tcattctttg tcctcaattt aaaacttccc tcgattggtc aagtcttcta ccttaggcat
    28921 aacttcctta ttatcccaat gctccacaat tttcccgttc tctaaacgga agatatcgta
    28981 ctgggcataa gcaacgccat caatctgagt ctgaccatag ctaaccacat agtttccttg
    29041 tcctaagagt tggaaaacaa agtcaaaagt gacactatat tcagccacat agtttttata
    29101 agcagcactt ccttgtccaa tatcatgatt atgctgaatc aaatcgtctg ccacataatc
    29161 actccactgc tctagctccc cattttggaa aatttctgtc aagaaacggc gaaccagctt
    29221 tttattttct gctttcttgt ccaaatcctt gatttcaaaa tctccaaaaa tttgatctag
    29281 ttggtcattt tcaggtgttc gatagtagtc aacgacatcc caatgctcaa caatacgacc
    29341 attctcatcc gcacggaaag tatccgtcgt cacccattga gcttctccac cattcagata
    29401 ttgatgaaca tgaacaaaga ccagattgcc atcctcaatg gtgcggacaa tcttaatctg
    29461 acgctctgga tgacgctcaa agaaatctgc aaagaaggct gcaaatcctt ctttcccgtc
    29521 aggaacacct gtcgaatgtt ggatataggt atcccctaca gactgggctt gagcctcagc
    29581 aactcgcccg tcttgaatgg catggatgta taggttgtga gcatttttca cttgttgtga
    29641 catattctaa acctcatttc ccttctcttt cagattcgcc aaaattcttt cttgaaaacc
    29701 ttcaaattgg tgaatttctt cctctgaaaa tcctttgtaa aagatagtat ccaatttctg
    29761 actgacacga tgccccactt ctttctggaa cttgcctaac tccgttaaaa ctaaatactt
    29821 cttacgcttg tcttttccac acggactaac aattacaagc ttttgttcct ctagcttttt
    29881 tatcatagtc gtcagcgtat tattcgcaag cccagtcgca agcgcgatat ctgtcgcagt
    29941 tgcgcagcca gtttcactat tccataaaac cgctaaaatc ttgccctgtt cacccctata
    30001 aagagcctca ggatcttgac tcagtaactt ttgaaaaatc cgcccattca acaaacgaat
    30061 atgatgggct agcaaatgac tatctttcat aacacctcca atttatttcg atatcgaaat
    30121 gaataaaata attgtaacac tcatcgttct aactgtcaac tatttcgatt tggaaataat
    30181 ttttgataat tatccacacc accatactcc ggctcaacta acttttaacg agagtttcta
    30241 aactccttcg tcctccagtc tacaaaagcc ttccattcgt actatcctat attttatgag
    30301 gggacacatt tttcctatca gaccatttat tttaaagata gaagtaaatc ataattgctt
    30361 ccatctgttc ttttatagta tattgaagtt agactagagc actgtatctt ctaaaacatt
    30421 gatagaaagc gatttgaatt tcccaatcaa tttgttcgta tttatagcat tttgaaacta
    30481 gaataggaca ccatgactgc taaaagattt ctataaattc atttgatttt cctaatcaat
    30541 ttgttcatat cttatttcat tccgctataa tttcacctta ccctatcttt ttcgtagcac
    30601 ccttcaaaca gcctatcccc taccgtttga cgattcctca cttcgctcca cttccattac
    30661 agaagtttct tcactactat gggctcggct gacttctcat gattccttgt tactactatt
    30721 tgaacgctca cgagatagat cttacaaaaa atgctttgat ccacaatgga atcaaagcat
    30781 tttaaagagt tcctcataca taagcgcaga agtcgcagtt cctctgtact tggcttcttc
    30841 tcttttgata aagcgagcca agttgagcaa ctcaggtgct ggatgtttgg gatttaggag
    30901 caattcacga ttgaccaggc ctgagagacg aactgcctgc aattgctcat ttgtagtagg
    30961 cagtttttta gcagtctcta ggagagcagc aactaaatct tcactcaaat catgtcgagc
    31021 atgattgtaa agatctttta taaggctttc taggtttggt tctgccatcc ctaccacctc
    31081 ccttatggtt taataatgtt taatcaaatc aaccgttgaa cgatccaatt tcttcaccaa
    31141 ggcttgtaag aaagcttgcg cttctaggaa gtcatccatt gcatagaggg tttggtgaga
    31201 atggatataa cgagcgcaga caccgatagt tgttgatggg acaccaccat ttttcagatg
    31261 agctgcacct gcatctgttc cgcctttacc acagtagtat tggtacttga taccagcttc
    31321 ttcagccgtt gtcaaaagaa aatccttcat ccctgggaga agcaagtgac ctggatcata
    31381 gaaacgaatc aaggttccat ctccaatctt gccttgacca ccgtagacat cacctgctgg
    31441 tgagcaatca actgcgagga agacttctgg gtcaaacttg gttgtagagg tatgagcgcc
    31501 acgcagacca acttcttctt ggacgttaga acccagatag agttcattgc cgagtttttg
    31561 acctgataaa gcttcagcta gctcgcttac catgaggaca ccgtagcggt tatcccaagc
    31621 ttttgagatg atattttttt cattggctgt caaaattgca gaactatctg gtacgatggt
    31681 atcaccagga cggatgccaa aactttctgc ctcagccttg tccgcaaaac caccatcaaa
    31741 aacgatatcg gcaatggctg gcatggttgg tccccccttt ccacgagtca aatgcggagg
    31801 aacagaacct gaaatcacag gaatttcatg accatcacga gtcaagagtt tgaaacgttg
    31861 gctgctaacc accatggggt tccagccacc gatttctacg acacggaagg taccatctgg
    31921 cttgatttcg ctgaccataa aaccaacttc gtccatatga gaagcgacca agacgcgcgg
    31981 tgcatccaca gcttctgaat gtttgatacc aaaaatacca cccaagccat ctgtcaccac
    32041 ttcatccaca tgcggtgtca acttttcacg aagataagca cggacaggcg cttcatgacc
    32101 tgagactgca gcaagttctg ttacttcttt aatttttgaa aataatgttg tcatttcagt
    32161 tccttctttc tttcatccat tttaccactt tttataggag aaggatagtg ggaaggtgga
    32221 tttctaagtt agtatcttag tcctgctcta tcttagaaaa ggatagtatt ctcttgcatg
    32281 tagtgcaaaa tctagtaaac attccaaaat taactcgaat atttatttcc aaacaaaaaa
    32341 acaatacacc atcaaagttg tttgtatttt tcatgaaatt tacagaaaat agttgacttc
    32401 cctttcttct ttctttaaat atatagttgg ttgagtttgg aatagtacgc tgtagctgct
    32461 gaaacatttc tagaaattaa tttgactttc ctaatagagt tgttcatatc ttatttcaat
    32521 ttactatagt acaaaactag aaaaggaaaa aatcatgacc aaaacaattc ttgttacagg
    32581 tgggactagc tacattggct cccataccgt taaagctctt ttaaatgctg gctataaggt
    32641 gcatgtcctc gataatctct ccacaggaaa tcgagcggct gtggatagtc gtgctagctt
    32701 taaagaactg gatgtttatg atgctagcgc cttaaaggct tacttagaag aaaatcagat
    32761 tgatgctgtc ctccattgtg caggtgaaat tgttgtgagc gaaagtattg aaaatccaag
    32821 taaatacttc actgccaacg ttgctggtat gaaccaagtt ctcaaagtct tatctgaagt
    32881 tggcattcaa aaaatcatgt tctcttcgac tgcttctctc tatggaaata actgtattga
    32941 caagccagtg actgaagata ccctgctcga ccctgtcaac ccttatgcag agacaaaact
    33001 gatgggcgaa cgaatgattt actggatggc caatcgctac gactggaaat atgttatttt
    33061 ccgttacttt aatgttgctg gggctgaaat ggatgcttca aacggtctgc gtgtgaaaaa
    33121 tccaactcac atcattccaa atatcaacaa gaccgcattg ggacaaaatg atagcttaaa
    33181 aatatttgga gatgactacg atacacgtga cggttcatgt attcgagatt acatttatgt
    33241 cttggacctt gcataggctc atgttaaagg aatgaactac ctatttcaag aagacagttc
    33301 ttctcaaatc tttaacttag gaactaaaaa aggctatact atcaaagaaa tctttaaaac
    33361 tgctgaagaa ttactaaatt aaaaaatccc acacgagatt gttgctcgac gtgctagtga
    33421 cccagccagt gtcctagcag atgcttcaaa agctaaacaa tatcttgatt ggacggctag
    33481 ctactccctc gaagatatta ttttatcaga ttaaggtaaa aacattttag aataggataa
    33541 caaaggagaa agtcttgttg ctctctcctt gttgtattta ttaaattgtc agaaatttta
    33601 ttgacagatt agaaaaataa tgttacattt atatccgcag atatctttcg ataccaaatc
    33661 tacatgaaag gacggggtat gaaactttct cattatttaa ttggcttact tctactccta
    33721 gtctttctct ctattagcat tgggaccagt gatttttcat ggggaaagct atttgatttc
    33781 gaccagcaga catggctcct ctttcaagag tcccgtctcc caagaactat cagtattctc
    33841 ctgactgcct ctagtatgag tatggcaggc cttctcatgc agactattac ccaaaatcag
    33901 tttgctgcac cgagtacagt tggaacgact gaagccgcca aactgggaat ggtgctgagc
    33961 ctttttgtct ttccatcggc tagtctgacc caaaagatgc tcttcgcttt tgtttcatcc
    34021 atcgtattca ccctcttctt cctagccttt atgaccattt ttactgtaaa ggaaaggtgg
    34081 atgttgcctc tgattgggat catctatagc gggattatcg gctcagtcac agaagttatc
    34141 gcctatcgtt tcaatctggt tcagagtatg actgcctgga cccagggctc cttctccatg
    34201 attcagaccc atcagtatga gtggctcttc ttaggcctca tcatcctgat aaccgtttgg
    34261 aaattatccc aaaccttcac catcatgaat ctggggaaag aaatcagcga gagtttgggg
    34321 atttcctact ccctacttga aaaactggcc ctctttctgg tggcgctaac gacaagcgtc
    34381 accatgatta ccgtgggtgg cctaccattt ctcggagtta tcgttcccaa tcttgttcgc
    34441 aagcgctatg gagataatct aagtcaaacc aaactcatgg tcgcactggt tggtgccaat
    34501 ctagttctgg cttgcgatat cctatcccga gttctgatta ggccctatga gttgtctgtc
    34561 agtctcttgc taggaatcat cggtagtctc ggctttatcc tacttctctg gagaggggga
    34621 cgaaaagatg cagactaaaa gcaaacatac caagctcttc tggattctca ttattcttgc
    34681 catcggagct tgtcttctct acttttggcc catcactcac ttgtcagcct ttgcttggaa
    34741 gttgcgttcc caaaagatca tcgtttatct cttggtagcc atcgcgactg ggatttcgac
    34801 cattagtttt caaaccctga cggaaaatcg cttcctgacg cctagtattt tgggaattga
    34861 atccttctac gtcctactac aaaccctact actggttttt gaaagcaagt ttcttcaact
    34921 tggcaaatcc cctatcttag aattcctagt cttacttctt gtccagtccc tcttctttct
    34981 caccttacaa ggttacttga agacactgat gaagcaagac ctggtcttca tcctgctgat
    35041 ctgtctagcg ctcagaagtc tctttcgaaa tatcagcacc ttccttcaag tcctaatgga
    35101 tccaaacgaa tacgataaac tgcaaaatag tctttttgcc tcctttcaac atctcaacac
    35161 ttccatccta gccatcggtt ctctgatcat cctcgctttg acaatctttt tctttcgaaa
    35221 agcagtcgtt ctagatgtct tgcacctgca aagagaaacg gctcagatat tgggactcga
    35281 tgttgaaaaa gaacagaaag agctcctctg gggaatcgtg cttttgacct caacggccac
    35341 tgccttggta ggacctatgg ccttcttcgg ctttatgctg gccaacctca cctacctgat
    35401 tgtcaaagac tatcagcaca agttactctt tatagtggcc attctggttg gatttattag
    35461 cttaaccttg gggcaagcct tgattgaacg agtctttgca ctggaaattc gtatcagtat
    35521 gatcattgag agtgtgggtg gcttcttatt ctttatctta ctatatagga ggtctcgtca
    35581 gtgaaactgg aaaacattga caaatccatt caaaaacagg atattttgca aggcatttcg
    35641 cttgaagtca gtcctcaaaa actgacagcc tttattggtc caaatggtgc tggaaaatcg
    35701 actctcctct ccatcatgag cagactaacc aagaaagatc agggagttct cagtatcaaa
    35761 ggacgtgaaa tcgagagctg gaattcgcaa gaactggccc aagaactaac catcctaaaa
    35821 cagaaaatca attaccaagc caaattgact gttgaagaac tggtcagttt tggacgtttt
    35881 ccctacagcc gaggtcgact tagatcagaa gactgggaaa aaatccgaga aactctgaac
    35941 tatttggaac tgaccaactt aaaagaccgc tacatcaata gcctgtcagg ggggcaactc
    36001 cagcgcgtct ttatcgctat ggtactggcc caggatacgg actttatctt gctggacgaa
    36061 ccactcaaca atctcgatat caagcaaagc gtcagcatga tgcagattct tcgacgactg
    36121 gtggaggaac tcggcaagac cattatcatc gtcctccacg atatcaacat ggccagtcag
    36181 tatgcagatg aaattgtcgc cttcaaggac ggccaggtct ttagcaaggg aagcaccgat
    36241 caaatcatgc aggctgacct gctcagtcaa ctttatgaga ttcccatcac gctagctgat
    36301 atcaatgaca aaaagatctg tatctatagc tagtaacata aaagctcaag ttagagaacc
    36361 ttcagtctct tagtcaataa gattaagaga ctccctaaat cgttatcaca ttttaaaaag
    36421 gagaaattat gaaaacatcc cttaaacttt atttcactgc cctagtggcc agcttcttgc
    36481 tcctacttgg tgcatgtagt acaaactcaa gcactagtca gacagagacc agtagctctg
    36541 ctccaacaga ggtaaccatt aaaagttcac tggacgaggt caaactttcc aaagttcctg
    36601 aaaagattgt gacctttgac ctcggcgctg cggatactat tcgcgcttta ggatttgaaa
    36661 aaaatatcgt cggaatgcct acaaaaactg ttccgactta tctaaaagac ctagtgggaa
    36721 ctgtcaaaaa tgttggttct atgaaagaac ctgatttaga agctatcgcc gcccttgagc
    36781 ctgatttgat tatcgcttca ccacgtacac aaaaattcgt agacaaattc aaagaaatcg
    36841 ccccaaccgt tctcttccaa gcaagcaagg acgactactg gacttctacc aaggctaata
    36901 tcgaatcctt agcaagtgcc ttcggcgaaa ctggtacaca gaaagccaag gaagaattgg
    36961 ccaagctaga caagagcatc caagaagtcg ctactaaaaa tgaaagctct gacaaaaaag
    37021 cccttgcgat cctccttaat gaaggaaaaa tggcagcctt tggtgccaaa tctcgtttct
    37081 ctttcttgta ccaaaccttg aaattcaaac caactgatac aaaatttgaa gactcacgcc
    37141 acggacaaga agtcagcttt gaaagtgtca aagaaatcaa ccctgccatc ctctttgtca
    37201 tcaaccgtac ccttgccatc ggtggggaca actctagcaa cgacggtgtc ctagaaaatg
    37261 cccttatcgc tgaaacacct gctgctaaaa atggtaagat tatccaacta acaccagacc
    37321 tctggtatct aagcggaggc ggacttgaat caacaaaact catgattgaa gacatacaaa
    37381 aagctttgaa ataagccact tcaaactcaa tttaatactc aatgaaaatc aaagagcaaa
    37441 ctaggaaact agccgcaggt tgctcaaaac actgttttga ggttgcagat gaaagctgac
    37501 gcggtttgaa gggattttcg aagagtataa aattttgaca ttctaaaacg catcctatca
    37561 agttcactca aacctgatag gatgcgtttt tatcattttg aaatctattt accccacctc
    37621 attccccttc ttgatttcgt ttaagggaaa agtggtctgg aacggggtcc ttacctgttt
    37681 tcgaccaggg atgacaacgt aaaatccgag ccaagcccat caataccccc ttaaaaccat
    37741 gtttttcaat agcctgaatc atgtagttgg aacaagtcag ctcaaagcga caagagggtg
    37801 gaaagactgg tgagataaaa cgttggtaaa agcgcacagg cgctattaaa attcgtttca
    37861 ttatttctta gttacagcca tggtgtgtag ttggctgatt tcttttttat taagacgacg
    37921 ggattctcct ggacggagtc ctgtcaagtc taggtgtccg aaacgagtcc gagacaactt
    37981 atctacttgg agaccaacag cttcaaacat ctttttaacc tgatggttac gcccttcatg
    38041 gatggtcaac tgcaccacag agcgattttt gactgggtcc actttgagaa tttcataaac
    38101 agctggcttg gttttcttac catcaatctc aagaccacgg gtcaaggggc ggagattgtc
    38161 cttattggcc acacccttaa cacgcgcgac ataaaccttg tcaatctcat tacgagggtg
    38221 aatcatctcg tctgtaaagt ccccatcatt ggtcaaaatc aagacacctg atgtatccca
    38281 gtccaaacga cccacagggt aaatacgctc tttgacattg ggcaagaggt cgacaaccgt
    38341 cttgcgaccc ttatcatctg tcacactgga aatcacaccg cgtggtttgt taagcagata
    38401 gtagaccttt tcttcgttgt agataggttg accttcaact tcgaccttgt cgcctgactt
    38461 gatagtggtt gctagttcac gcaccacttg gccgttaacc gtcaccaagc cttgcttaat
    38521 cagctcttct gcttttctcc tactggccac acctgcgtgg gcaatatact tattgattct
    38581 catcttcttc tatcctttca ccaaataatt ggctttcttg ggcttgaatc tcaagctcat
    38641 caatcactgg taattcttct aaatggttta tccccatgta atctaggaaa taatccgtag
    38701 tcacatagag gttggggcgc cccaatactt cctttttccc gtcttccttt atcaggtcaa
    38761 aagcctgcaa ctttgccaag gctccactcg agttaactcc acggatggca tcaatttcta
    38821 tccgcgtaat cggctgtttg taggcaataa tggacaaggt ctcaagggca gcccgagaca
    38881 agctctggtt gataggcgcc ttagagtatt ccttcaaaat ctctgcaaat tgagacttgg
    38941 tcaccaatct ataagcacca cttgtctcaa tcaaagccaa actggaatct gggtcctttt
    39001 catacttctg ggctaatttt cctaaactct gctggatgcc tgtcggtggc agagagagga
    39061 gttcagctaa ctggcggacc cgaatcccat cttcacccgc tacaaacaag agcgcttcta
    39121 tttttgctaa agtactcatc tttcctctct atcaagtcta gctttgaggc acttgacttt
    39181 cttccttctt ttccatgaga tagatatctc caaaactctc ctcttgcacg aggatcagct
    39241 cctgggtttt gattaactct agggttgcca aaaagagggt gatgacctct tggacattct
    39301 gggcttcctt gaacaaatcc tgcaagcgca attgatctcg tccaatcaag gactctttca
    39361 cgataatcat catgtcctca atcttatact catcccgcaa gatagtcgtg tgattttgtg
    39421 caaactcctc ttttttcttg gctaggatat ttgaaaaagc caaaaagagg tcaatggtcg
    39481 tcttgtcatg cacaagctcc gcatcttcgt aaatcaactc tgtcggcgct ttggaataat
    39541 actgggcccg ttcttggtgc ttggcttcca agtgctcacc caagagcttg aacttgcgat
    39601 attcttcgat ttgagagagg aggtcctgct ccaggtcatc ccccaagtct gtcacttctg
    39661 ctaccttcgg aaggagttta cgactcttaa tcagcatgag ctgactagcc atgaccatgt
    39721 actcacccgt cacttccaga cgcatggcct gcagggttga aacataggct agatactgtt
    39781 cgatgacttc cgtaatgggc acatcgtaga tatccatctg gtacttagaa accagatgca
    39841 agagcaagtc cagggggcct tcaaaatctt ttaatttaat atccattatc tatatttttc
    39901 taaggtcagg actgttttta atcctaattt ttttgcaatt tcgtacaaat cgaccttgtt
    39961 ttctatttgt cttagaataa actgttcacg taagacttga gctgataagg atggaaaacc
    40021 tttctccttg acaaaagatt ctaactgacg aaaggcccac tgacgagaat agggtttctc
    40081 tcctctttca aaaagatagg tctgccccat caagggttcc aattctgaaa gcaaggccgt
    40141 gggaatggtg acaatcctct gttgggaagc cttgctgatt cgcaacacct gaaaatccag
    40201 attgatgtcc gcaaccttga tggctaaaat ctcactgggc aagagcccca tttctaggat
    40261 taagagcgct agcaagcggc cctctggatg gtcgctttcc tgccaaaaag agtctaggta
    40321 tagaatctct ggcttttccg tcttcttttc agcttgtttg gctaattcca agcggtaaaa
    40381 gctgtccacc tctccttttt gatagagaaa gtatagaaat tggttacagg ccgaaatctt
    40441 tcgcttctgg gcgctgattt ttagattggc tagctgggct tggtaaatct tgagactggt
    40501 ctcagaaatc cgctcaccta ccatgtctaa aaattgctcc aaatcatact tataggactg
    40561 cttggaattg acagacaagc cctgcttttc ctctaaaaag gctgaaatcc tgtctctcat
    40621 tggcatcgaa tctcatattc cttactaaag tcatgcaaga gggcattaac ggccttgagg
    40681 atggacttac gcgtaataat cccttggaaa ataccctctg catccacaac cggtaagaag
    40741 gactcatcta ctagcttgtg caagacctcc gtaatggtga aatcaggcga aacaaccgct
    40801 acgtccgttt ttgtcatatg aacgatatcc gtatccgcca tgatttcttg gctcaagtca
    40861 tgctccatct gataagccat aatatctctg agtccaatcg tcccaacaaa ctgtttttca
    40921 tctgtcacaa cgggaacacg ggtataggtc atctgactga gcaagagggt cgcatgatcc
    40981 gcattgtggg tatcaatcaa cacagctaga tttttagcag gggtcaaaaa agtttcctcc
    41041 tgccccaaca agaaagtctc aaactccttg gcaatcatcg gctaaactcc ttggacaaac
    41101 ctggatacac ctcgtgatct cgtgtcaaaa agtccacttt gaagtaacta tcatcaatct
    41161 ccacacgagc atagagacat tctctgatgg tacctcgtgg ttgactgata gaacctggat
    41221 ttagaaagag gatcttgcct tccaaccaag cacttggcac atgcaagtga ccatagaggc
    41281 agatagcggc ctcttcctcc tgagcccagt agtccaactt ttgaaagttg aaattgatgt
    41341 caaacaagtg accatgagtt tggataatct tggtcgaacc aagctcagtc accagacgtt
    41401 ctgggtagcc ggcgtagaag tccatgtttc ctttaacaac gcggatgccc tcccaaagtg
    41461 gagaatccgg acgtagttca gaatcgccgt tatgaaaaac ggcatcgact ttgcccacat
    41521 agcgatcacg gacttcttcc acaatcaagc tatcgccatg ggaatcgctc attacaatga
    41581 tggtttgctt tgccatgatg gaaatacctc caaaagtttc ttaacggcta aggcacggtg
    41641 agattgacta tttttttctt ccagggttaa ttcagctgat gacttacctg tctctcctac
    41701 aaggaagagg ggatcatagc caaagccatt ttcaccctta ggttcaaagt taatataacc
    41761 tgaccagtct gcttcaacaa ctaaactttc cttatttggg ctggctacga ctagggttgt
    41821 gtggaactga gccgagcggt ccttgagttc aaagaccatg gccaattcgt gcaagagttt
    41881 ggcattattt tcacggtcag ttgctcccac acctgcgaaa cgagctgacc agacgcctgg
    41941 taagccacca aggacatcga ctttgagacc agaatcatct gccaaaacca tcttgcccgt
    42001 taattgagaa atggtttctg ccttaaggcg ggcattttct tcaaaggtca tacctgtttc
    42061 tgctacttca ggcaggtcag ggtagtcatt aagattttcc acatcgtagc ctaacttatc
    42121 aaagatagct cggaattcct tggttttgcc ttcgttacga gtcgcaatca acaaggtttc
    42181 tctgaccttg cttgtctcaa agaaatcatg aacattgacc ccttctttag gcaattctac
    42241 atacaagagt tgcccatttt caaccaagag cagggcccca tgacgttgaa taacttccaa
    42301 gtttcgtccc atttcttgat taagcatgtc taccacaaag gagaacaaac ggtaggtaga
    42361 accatagcgt aaaacagtaa ctgaaagcgg gaaaccatac tcttcatctc caaatatttt
    42421 ggagaattca aacagaggaa aatctgtctt atagtcgctc aaactgttaa cgccaccaaa
    42481 aatactataa gacccaacat accaatcctg gtcatcctta tattcataaa ttttatttgt
    42541 cataattcta catgctccac ataaatctct ttttccagcc attcttcacc aatttgtgca
    42601 aaactttggc tactggctgt tgtgtaaaaa cggtgatgga gtggtccagc atcgcgacca
    42661 cgattgattt caaaataatt gagtaagact gagatatccc gtacgcactc tgccccacta
    42721 tcgatgagct gaacctttgg ccccatgaca ttttggataa tagggcgaag gagtggataa
    42781 tgagtacagc ccaaaatcag gctatccacc tttccaacca agggacgcag ggtttcatag
    42841 accaccttct tggtaacact ggttgacagg gcacctgact caaccaaggg agcaaacttg
    42901 ggacaggcca agctctccac ctgtaagtcg ggatccagat catggatttt ctgacggtat
    42961 atgtctgatt gtaccgtcat gggcgttcca atcactccga ttttcccacc ttgactggac
    43021 ttgatggctg ccgaagctcc tggcaaaatt acacccaaga caggaatatc tagttgagcc
    43081 ttgatttctt cccagacgac cgcagtcgca gtgttacaag caatgacaat cattttgaca
    43141 tccttggtca agagaaagtt gaccagctgc caagtatatt cacgaatttg ctcagctgga
    43201 cgggggccat agggcgcccg cgccgaatct ccaatataga cgatttcttc atggggaagc
    43261 tggcgcatga gctcgcgcac aacggtcaag cccccgacac ccgaatccaa aaaaccaatt
    43321 ggtcgattat ccatacagtc ttctttctag tcttttttct gattgatcgt tcattatgat
    43381 tccttgtact gaacgaactg accgacagct tgatagaatg tcaactacct ctctcttaat
    43441 cataatcaaa tatcaataga atgcaaggaa aaagtctcat ccctaaacca taaccaacat
    43501 agtgagaagt ctggaacttt catcccagac ttttccttat ttattttttc tttttattgt
    43561 tagcaagggc tgccttttgt tggcggatga tttggtggta aacttgttgt accttagctt
    43621 cgcttggttt ttgaccattt gcactcaaaa gagtacgaac tgcttcagca ttcaaacgtg
    43681 ggttgtcagc aaattctttt tcgatttgct tacgaaccaa gtacattcct ccaagagctc
    43741 ctcctagaaa agctagcaca atcaatacaa ttgctaaaag taaatccatc atttttctcc
    43801 tgtttctttt tgagtccctt tcattatacc acaaactagc caccctgacc agtttgttct
    43861 acactttcag ggatggaata gacagcaaaa agaaccctgc ttttctgaaa aagaggtctc
    43921 cttgctaagt ttaatttaca taaatagcca gtgtttgata gggttttagt agaattttct
    43981 cagacacttc tgcatcttca tagtttgaaa tcaaaatctg tccattttgg tagactgctg
    44041 gcaagtcgat ttccacttct ttagcataaa agttattgag cactagtaac ttttgatcct
    44101 caaactggcg ttcaaaagcg tagacttgtt tgctatcttc aaaggctggt ttgtaacttc
    44161 cttctgaaat gattggcatt tccttacgca gtcgaatcaa gtcttgatag aaggtaaaaa
    44221 tcggaccctg gatttcattt tctacattga tgtctttata ggatttacca gctttcaacc
    44281 aaggagtgcc tgttgaaaat cctgcatttt ccgaagcatc ccactgcatg ggaatgcgtg
    44341 aattatcacg cgacttagct tgaataatct ggaaggcttc ttgctgactc tttccttctt
    44401 ctaggagcat ctgataggca ttaagcgatt cgacatccac gtaatcagcc atagaatcat
    44461 agtctgggtc aatcatcccg atttcctcac ccatgtagat ataaggtgtc ccacgtgaca
    44521 ggtgaatgct ggctgctagc atggtggctc cttccttgcg gaagttttga atatcgacaa
    44581 aacggttcaa ggcacgtggt tgatcgtgat tgttccaaaa gagggcactc caaccgtctt
    44641 tatcactcat ttccttaccc caactatggt aaagactctt caactcttca aaatcaaagg
    44701 gagccaaggt ccacttttgt ccatccttat agtccacctt gaggtgatga aaattaaagg
    44761 tcatggataa ttcctgacga tcaggcgacg aatagaggac acagttttcc atggtggtag
    44821 aagacatttc cccaactgtc ataaagctat cgtcagatcc aaaagtggct tggttcatca
    44881 tacgcaaata gttatgaacg atgggtttgt ctgtataagc tggcttccct tcattttcag
    44941 gacagtccac tgaaacctcg tccttaccaa tcaaattgat cacatcaaat cgaaaacctt
    45001 tgacaccctt gtcgcgccag aaattaacaa ccttgaaaag ctccttacgg acattgggat
    45061 tgcgccagtt aaggtcagcc tgggtctcat caaataggtg aagatagtat ttcccagtat
    45121 ccccgaaagg cgcccatgca gaaccaccaa acttagactg ccaatctgtt ggttggtctt
    45181 ggatgaagaa aaagtcttga taatacttat caccagctag ggctttctga aaccattcat
    45241 gctctgtcga acaatgatta agtaccatgt ccagcataaa gtcaatcttg tgctctttac
    45301 cgatacacac catttcctca aaatcagcca tatcaccaaa aagaggatcc actgccatat
    45361 aatctgaaat atcgtaacca ttatcccgtt gaggacttgg atagaatgga ttgagccaga
    45421 ccatatccac acctagtttg gctagatagg gaatttttcc gataatccca cggaaatccc
    45481 caataccatt gccagtggtg tctttgtaag attttggata gatttgatag actacttttc
    45541 ctttatcaag tgtcatctgt ttctcctttt ctgataaaag ggaggaagca gtcttccgtc
    45601 cctatttgtg ctatttcaat tatactcaat gaaaatcaaa gagcaaacta ggaagctagc
    45661 cacaggttgc tcaaaacact gttttgaggt tgcagataga gctgacgtgg tttgaagaga
    45721 ttttcgaaga gtattagatt cgtgtagcga ccatgagaga tgctccagct tgaatcgttg
    45781 tcggataagt tccgggaata gtcgctgtat aagcatcttg gttggtgatg ataacaggag
    45841 tttctgtcac cagacctgca gccttaatga catccatatc aaaacgaatc agttgctgac
    45901 caactgtaac gtgatctcct tggactacaa gactttcaaa acctttgcca tcaagaccta
    45961 ctgtatccat accgatgtgg atgagcaatt caactccctc gtcagagaca atgccgatgg
    46021 catgcttggt agggaaaaga accgtcactg tcccattaac tggagaggtc aactcacctt
    46081 ggcttggttc aatgactaga ccttgcccca tgacacctga tgcaaaaata ggatccgtcg
    46141 cttgactcaa ttctttcact tggccagtta gtgggctgat aatttctacc gaagtaagtt
    46201 ctactggttc atggttcaca aattctgctt cttcttgagc aacgaattct gcctgcaagt
    46261 tcgtatcgcc ctctgttttt gtaaagagac cagccttgcg gaagaagaaa gtcaagagca
    46321 ttggaacaac aatcgcaact agcatagttc ctgcaaatgg cagcatgtat tgaggttgaa
    46381 tagagagaat acctggcaaa ccaccgatac caatagaagc cgcagttaca ttaaaagtaa
    46441 cggataacat gcctgcaagg gctgaaccag tcatcccagc aacaaatgga taaatatatt
    46501 ttacgttaac cccaaaaaga gctggttctg taacaccgag ataggctgaa atggttgcag
    46561 gaagtgaaac ctgagcctca cgctcatcat ggcgatgcat gaaataatag gcaaacacgg
    46621 ctgagccttg agcaatatta gaaagagcaa tcattggcca tagggcagtg ccaccagcat
    46681 ccgcaatcaa ttgtgtatca atggcattgg tcatatggtg cagacctgtg atgacaaatg
    46741 gagcgtagag ggcaccaaaa attgcaccga agagccattt aactggacca gttaaacctg
    46801 ccaagacaac tgatgaaagt ccttgtccaa ttgtccaacc gattggtccc aaaacagtat
    46861 gagccaaaat caaggctgga atcaatgaca agaaaggtac aaaaatcata gaaatgactt
    46921 ctgggatatg cttgcgccag aagatttcaa gataagatag actcaaacct gcaagcaagg
    46981 ctgggataac ttgggcttgg taaccgatac gattaacagt aaaatagcca aaattccaaa
    47041 cccagtttgc cgcgatatca gctgctggcg ttgaagcaac cgcataggca ttgagcaact
    47101 gaggcgatac caaacagatt ccgagaacaa ttcccaaaat ttggctggtt cccatcttac
    47161 gagaaacaga ccaagtaatc cctactggta agaactggaa gatagcttca ccaggcaacc
    47221 agaggaaatg attaacacct gcccaaaact gagaggattc tgtgatggtc ttgccatcca
    47281 acatcgacca atggacacct tccaagacat tacggaaacc gaggatcaat cctccgacta
    47341 tcaaggctgg aataatcgga gtaaaaatct ccgccagagt ggtcatgaca cgttggacca
    47401 cgttttgatt actcttagct gcagacttgg ctgcttcttt ggaaacaccc tcaatacctg
    47461 aaacagctgt aaaatcatta taaaagatgg gcacgtcatt tccaatgatt acctgaaatt
    47521 gacctgcatt tgtaaaggtt cctttaacag ctggaattga ctcgatagct ttaacattag
    47581 ccttcttatc atttcctaaa acaaagcgca tccgtgttgc acagtgagtt acggcagtca
    47641 cattttcttt gcctccgatt gcctgaagca gatctttggc ttcttgttca aattttccca
    47701 tttgattctc cttatacttg tcaaagcaag tttgatttga taagtatatt gtaaacgata
    47761 ccaaacttgt ctgcaacttg tttggtataa aaagggtgtt tttttgtaaa ttttctagca
    47821 cttgtatggt aaaatagata caggtgttca ttaaactaga ctaaaaacct atttaagcag
    47881 gcaaaatgaa gaaataccaa caattattta agcaaatcca agaaaccatt caaaacgaga
    47941 cttacgctgt cggagatttc cttcctagcg agcacgacct tatggagcaa tatcaagtga
    48001 gtcgtgatac cgtccgaaag gccctgtctc tcctccaaga ggaaggattg atcaaaaaga
    48061 taagagggca aggttctcaa gtcgtcaaag aagaaaccgt caatttccct gtatccaacc
    48121 taaccagcta ccaagaacta gttaaagaac ttggactgcg ctctaaaacc aacgtggtca
    48181 gtctggacaa gattattatt gataaaaaat cctcactgat aaccggtttc ccagagtttc
    48241 ggatggtttg gaaggtggtc cgccagcgtg tggtggatga tctggtatcc gttctggata
    48301 cggactatct ggatatggaa ctcatcccaa atctcactcg ccaaattgct gagcagtcta
    48361 tctattctta tatagaaaat ggcctcaaac tccttattga ttatgctcag aaggaaatca
    48421 ccattgacca ctcaagcgac cgagacaaga ttctcatgga cattggcaaa gacccttatg
    48481 tcgtttcgat taaatcaaaa gtctatctcc aagacgggcg ccaatttcag tttaccgaaa
    48541 gtcgccataa gttagaaaaa tttagatttg tagattttgc aaaacgcaag aaataaaaga
    48601 ctgagacacc agatctcagc ctttttcttt atcccaaaac taattcatca ctgaccagac
    48661 tttggccact atttttctgg aagagatgca taaggtcttc aactgtcaga tgctttttct
    48721 cttctccctt gacatccacc actatcttgc cttgatagag cataatgaga cgattgccgt
    48781 actcaatcgc atgattcata tcatgggtaa tcatcaaagt cgtccactga tggtactcca
    48841 caatcttttg cgtcaagtcc atcaccattt gactggtttt cgggtcaagt gccgcagtat
    48901 gttcatccaa aagcaaaagt ttgagtttca ccagagctgc catgactagg gtcaaagcct
    48961 gtctttgtcc tcctgagaga tattgagtat ctacttttaa gcggttttca agaccaatat
    49021 tcaactcctt caaggcctct tggaactgga ttctatcctt ctccttcacg ccccaaccaa
    49081 gccctctctt ttgcccacgt ctcaaggcaa tagccatatt ctcctcaatc gtcaaacgag
    49141 aagctgttcc catcttagga tcttgaaaaa cacgggcaat atccttggct ctctttctga
    49201 cactcagatg tttaatggat ttccctgcca gtagaaggtc cccttcgtcc accgatagat
    49261 taccagccaa gatattcatc aaagtggatt ttcctgctcc atttccacca atcacagaga
    49321 taaaatctcc ctcttcaacc tctaaatcta atcctttgag gacatggttc tcattgaccg
    49381 tccctgcttc aaatgtcttg tgaatatttt caagtgttaa caaacttgcc ataactttct
    49441 cctcctattc atttctcaat ttcagaccac gaatctttaa tctcttttgc aatgctggtg
    49501 caaataaaac caaagcgagc aagattgcat taaagagacg taccaagttt tgatctagat
    49561 ttggaatttc atagatattt aaaataatca aacggtaaac aatagcaccg attccgatgg
    49621 ataataagcg gcctccaatg gtcaagtcgt gtatcaagac ttccgagctc aaaccaacaa
    49681 caatggttcc tgtcccagaa gtcacatctg aaaatccatc attttgggca aacaaggaac
    49741 cacatagggc aatcaaaccg gttgaaatca tgtaaccaac aatcttcatg gtgtttacat
    49801 tgactccatt ggcctcactc atcgggatat tgtccccagt cgaacgcaag accaaaccaa
    49861 tctctgtttt catcaaaagg gtcaaaacca aacaagtaag agacagacta aactaagtga
    49921 gaaaacagct ccttcatttg tcagacccaa gctcgccaac tgtttaaaga cggttgcaga
    49981 atctcccaag gaaagattgg gtacactgcc catgatttta atattgattg aatagagccc
    50041 tgtcaaggtc acaatccctg tcaagagagc tgggattttc atcttggtgt ggagcattcc
    50101 tgatataaga cctgctacca tacctgccag caaagcaagt aaagtcgcaa gccaaggatt
    50161 tgcccctgcc tgtatctgtg atacaacgat tgctgccccc ataggaaagg ctccctcagc
    50221 agtcatatcc gcaatatcca aaatacggaa agtcaagtag accccaattg ccataatcga
    50281 ccacaacaaa ccttctgata aactagataa cacaaaattc atcttaatcc tccttattcc
    50341 ttgccttcta acttactaat atcaattcac aatgcatctg ccatttcttg attagtatgc
    50401 aattccagtt tttcaggcaa ctcaactgct atattttctg gttcctcacc ttttaaaaca
    50461 cgaatcagca tgcgagctgt ctgtcttccc aattcttcat aattggttcc gtagttatac
    50521 aagccaccaa cagcaatcat ttctgttgaa ccaccgaata ctggaacctt gtgtttaata
    50581 gaaacctgct taactgtttc catggttgac gaaatgatat tatcagttgg gacaaaaacc
    50641 atatccacct ctgccatcaa actctctgct gccgccttga cgttattact gtccaagatt
    50701 gttttttcaa caacggtaaa gcctttttct ttcagaaatc gcttagcttc atccttttaa
    50761 acaaccgaat tgggctcgct ctgagtatag aggattccaa tcgttttagc ctttagcaac
    50821 actttcttta tcaaattgat ttgggttgaa atggcatctg atgactgatc gcttgtccca
    50881 gttacattgc ccccaggatg ttctcttgac tcaaccaact tggcactgac tgggtctgtt
    50941 acagctgaaa agataactgg tgtcgtttgc gtcgtattgg ccaagctctg agcagaaggc
    51001 cttgcgatgg ctagaacgac atcgctggat tctgctagtt gctgggaaat cgtttttaga
    51061 tttctttgtt ctccctgtgc attttgcaaa tcaatctcaa tattttcccc ctcaacatag
    51121 ccttgtttgg ccagctcatc cacaaatcct tctctagtag cgtctaagga ctggtgggta
    51181 ataaactgcg aaataccgat acgaaagaca tctcttttct tatctgcctt caactgatgc
    51241 aaactgatca gagaagtcaa gaggatcccc actaccaaga gggggctagt gattttcgaa
    51301 caactttcat aatgaaactc cttctcagaa aagataaaac aaaaaaacgc ctagatacta
    51361 tctaaacggg tacttgaaat aacctaacaa gttacaactt agctggtcca tttagatatt
    51421 catctatatg gaccacaatc aaaaatctta gccacataga tacaaacaaa ttgcttgaac
    51481 tgtttgcatc catggtgaca tgtctacaaa cactatctaa agtagctaaa gtaaaagttt
    51541 tgattcatag ttacggcttg tctcttattc atttcttttt ctgctttctt ttttgatcct
    51601 tcctatccta ccaccttttt catcacctgt caataatatt tcaaaatttt ttaaaatttt
    51661 tcgaaaattc tttcag
//
LOCUS       DAVBIC010000006        48474 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.006, whole genome shotgun sequence.
ACCESSION   DAVBIC010000006 DAVBIC010000000
VERSION     DAVBIC010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 48474)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48474)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48474
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.006"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            complement(308..1474)
                     /gene="recA"
                     /locus_tag="VQ664_000350"
     CDS             complement(308..1474)
                     /gene="recA"
                     /locus_tag="VQ664_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HET2788582.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVPLDLGDELEIEIEE"
     gene            complement(1529..2785)
                     /locus_tag="VQ664_000351"
     CDS             complement(1529..2785)
                     /locus_tag="VQ664_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HET2788583.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNLLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQVDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGISSIFKGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQDQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            complement(2869..3885)
                     /locus_tag="VQ664_000352"
     CDS             complement(2869..3885)
                     /locus_tag="VQ664_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HET2788584.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNVERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEKALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSVGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNILRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            complement(3893..4411)
                     /locus_tag="VQ664_000353"
     CDS             complement(3893..4411)
                     /locus_tag="VQ664_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2788585.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVRHIGDLFIVIGKRYWNNG
                     LGSLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLIG"
     gene            complement(4401..4844)
                     /gene="tsaE"
                     /locus_tag="VQ664_000354"
     CDS             complement(4401..4844)
                     /gene="tsaE"
                     /locus_tag="VQ664_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HET2788586.1"
                     /translation="MYTKNEEELQALGERLGHLLAKNDVLILTGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLLEELQYGV"
     gene            complement(4930..5550)
                     /locus_tag="VQ664_000355"
     CDS             complement(4930..5550)
                     /locus_tag="VQ664_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2788587.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            complement(5933..6796)
                     /locus_tag="VQ664_000356"
                     /pseudo
     CDS             complement(5933..6796)
                     /locus_tag="VQ664_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            6961..7155
                     /locus_tag="VQ664_000357"
     CDS             6961..7155
                     /locus_tag="VQ664_000357"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2788588.1"
                     /translation="MKKKRVSRMKKNRGIQKLAILVLLGVFMFSNTIPYQQFIQKNRQ
                     LEIRVQSQKKSNGLDVGKAD"
     gene            7470..7766
                     /locus_tag="VQ664_000358"
     CDS             7470..7766
                     /locus_tag="VQ664_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000911560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HET2788589.1"
                     /translation="MLKFRKVVASSLAVLAFSLALPVLAVSHRGGEWTYGGHHDPNNW
                     GAFSNYYHGSQYHWAYVGSNGRNNQKTVYAGARSAAYAFVNTNFGEQVTFDAGW"
     gene            7869..9884
                     /locus_tag="VQ664_000359"
     CDS             7869..9884
                     /locus_tag="VQ664_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HET2788590.1"
                     /translation="MKKLFILISNLLASLFFVWVFTIWTDTYVSYYYPNVVVHDSSPE
                     TTFQHVATRLEKLAEETDSFIAIQHQDPNSEGTTVFSYTTFGDGKLPDGLQEKKLEDA
                     QSSSVETNYFVFDGHLDIHLLREELSQLGLTNMNLTIPSKLSTLMAIFSNGFQLISLL
                     IFILTFIALTLISQISQLRSSGIRLISGEKRWSIFLRPVGEDLKGIAVGFSLAGVLAI
                     LMQKILSLPTQSLMTIGAGLLSYNLILLSISLFFAQLFAVGIKKIHLMQIIKGQVPVR
                     GIISLILIGQLLAIIIVTLGIGSSLKYSQAWQQHRIGQEAWSQERQLITLSISREGTS
                     PGFDEQAQRKLRTWYQLMDLAVSEQKAFLSRHQLIDRTLQNGMASSKNLITSTEWHDY
                     NPNGNVLIVTPQYLERQNIPVDTTIEQKMNHLDVGEFVLLLPEHLRSEEEHYKSVFED
                     DLTSRMSSQDERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQ
                     SILFWIDAVQNYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVM
                     LAGAGLGIATSILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLG
                     FVASVFLQVEIGVAFLVLLLFTGLSLLQLHVQMQKENKMSMLVLKGG"
     gene            9886..10518
                     /locus_tag="VQ664_000360"
     CDS             9886..10518
                     /locus_tag="VQ664_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2788591.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLTYLDLDKRIFELSGGESQRVALAKVILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDRLK"
     gene            10659..10937
                     /locus_tag="VQ664_000361"
     CDS             10659..10937
                     /locus_tag="VQ664_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComA"
                     /protein_id="HET2788592.1"
                     /translation="MKKFDNYIVEKPCDSNSDKLQKILIIENLVDDILQFPLRINNSV
                     GEIFLLQPFQKKTIFIPCYFEEDIVKVKDDDKVEWNLLEFQKFRAFLA"
     gene            complement(11446..11859)
                     /gene="ndk"
                     /locus_tag="VQ664_000362"
     CDS             complement(11446..11859)
                     /gene="ndk"
                     /locus_tag="VQ664_000362"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HET2788593.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYPPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTI
                     RGDFAKAAGENEVIQNVVHGSDSEESAKREIALWF"
     gene            complement(11970..15647)
                     /gene="rpoC"
                     /locus_tag="VQ664_000363"
     CDS             complement(11970..15647)
                     /gene="rpoC"
                     /locus_tag="VQ664_000363"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HET2788594.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGDIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKAEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGEVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPYAVNEEEYLNPPVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            complement(15680..19291)
                     /gene="rpoB"
                     /locus_tag="VQ664_000364"
     CDS             complement(15680..19291)
                     /gene="rpoB"
                     /locus_tag="VQ664_000364"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HET2788595.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVVAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSSLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            19707..19777
                     /locus_tag="VQ664_000365"
     tRNA            19707..19777
                     /locus_tag="VQ664_000365"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19739..19741,aa:Cys,seq:gca)
     gene            complement(19975..21306)
                     /locus_tag="VQ664_000366"
     CDS             complement(19975..21306)
                     /locus_tag="VQ664_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HET2788596.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTDTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPVIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFNVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKVQITEVEIEEETE"
     gene            complement(21597..22421)
                     /gene="endA"
                     /locus_tag="VQ664_000367"
     CDS             complement(21597..22421)
                     /gene="endA"
                     /locus_tag="VQ664_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HET2788597.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSTANSPKTKLSQKKQ
                     APEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            complement(22460..22648)
                     /locus_tag="VQ664_000368"
     CDS             complement(22460..22648)
                     /locus_tag="VQ664_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HET2788598.1"
                     /translation="MNKKSSYVVKRLLLVIIVLILGTLALGIGLMVGYGILGKGQDSW
                     AILSPAKWQELIHKFTGN"
     gene            complement(22641..23924)
                     /gene="murA"
                     /locus_tag="VQ664_000369"
     CDS             complement(22641..23924)
                     /gene="murA"
                     /locus_tag="VQ664_000369"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HET2788599.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            complement(23948..24178)
                     /locus_tag="VQ664_000370"
     CDS             complement(23948..24178)
                     /locus_tag="VQ664_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HET2788600.1"
                     /translation="MVQLLFTLSSHMLFIYVSFYLLKDLVRWEKVLKVTAENTRKVRV
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            complement(24236..25273)
                     /locus_tag="VQ664_000371"
     CDS             complement(24236..25273)
                     /locus_tag="VQ664_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HET2788601.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     VNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            complement(25257..25745)
                     /gene="coaD"
                     /locus_tag="VQ664_000372"
     CDS             complement(25257..25745)
                     /gene="coaD"
                     /locus_tag="VQ664_000372"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HET2788602.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLCVGIFFNPHKQ
                     GFLPLENRKRGLEKALGHLENVEVVASHDELVVDVAKRLGATCLVRGLRNASDLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACYVPESILEEIRNEK
                     KD"
     gene            complement(25735..26274)
                     /gene="rsmD"
                     /locus_tag="VQ664_000373"
     CDS             complement(25735..26274)
                     /gene="rsmD"
                     /locus_tag="VQ664_000373"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HET2788603.1"
                     /translation="MKIVSGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEVGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQMTKEVGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYAKEQIVADIEKMAERELFSEDVMVVCETDKTVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            complement(26339..27331)
                     /locus_tag="VQ664_000374"
     CDS             complement(26339..27331)
                     /locus_tag="VQ664_000374"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HET2788604.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            complement(27443..28126)
                     /locus_tag="VQ664_000375"
     CDS             complement(27443..28126)
                     /locus_tag="VQ664_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HET2788605.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYLLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            complement(28182..28922)
                     /locus_tag="VQ664_000376"
     CDS             complement(28182..28922)
                     /locus_tag="VQ664_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HET2788606.1"
                     /translation="MTIITSKANSVVKNAKKLHQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFALENYRNQLAAFPQTVWISEDILLDLADSQTPQGIVAVVQKEEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSQALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVAAGILIFHLS"
     gene            28956..29234
                     /locus_tag="VQ664_000377"
     CDS             28956..29234
                     /locus_tag="VQ664_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HET2788607.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYSDFKIAN"
     gene            29312..30238
                     /gene="yidC"
                     /locus_tag="VQ664_000378"
     CDS             29312..30238
                     /gene="yidC"
                     /locus_tag="VQ664_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HET2788608.1"
                     /translation="MKSIKRFAFSAMGVAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVREELAKNPPKASAFSK
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(30313..31107)
                     /gene="pflA"
                     /locus_tag="VQ664_000379"
     CDS             complement(30313..31107)
                     /gene="pflA"
                     /locus_tag="VQ664_000379"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HET2788609.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTSQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKKLMDTESYQDYMKRVHG"
     gene            complement(31233..32483)
                     /locus_tag="VQ664_000380"
     CDS             complement(31233..32483)
                     /locus_tag="VQ664_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HET2788610.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERVAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGIHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     ISLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTSAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEAVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            complement(32550..33377)
                     /gene="purR"
                     /locus_tag="VQ664_000381"
     CDS             complement(32550..33377)
                     /gene="purR"
                     /locus_tag="VQ664_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HET2788611.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLHEFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            complement(33644..34585)
                     /locus_tag="VQ664_000382"
     CDS             complement(33644..34585)
                     /locus_tag="VQ664_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HET2788612.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMTNKIFAMDNRSFYKPDLD"
     gene            complement(34575..35831)
                     /locus_tag="VQ664_000383"
     CDS             complement(34575..35831)
                     /locus_tag="VQ664_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HET2788613.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVVVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYETGDKDEIERCRKSLLASVKRFARDIRNKYI
                     APPRTTNFGILFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            complement(35833..36495)
                     /locus_tag="VQ664_000384"
     CDS             complement(35833..36495)
                     /locus_tag="VQ664_000384"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HET2788614.1"
                     /translation="MSEYKLSENNWTRVAVFAGGDRGHYRTDFDGFVGVDRGSLWILE
                     EDLPLALAVGDFDSVTEEERQVIQKRAQYFVQARPEKDDTDLELALLTIFKQNPQAQV
                     TIFGALGGRIDHMLANVFLPSNPKLASYMHQIEIEDGQNLITYCPEGISQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            complement(36458..37114)
                     /locus_tag="VQ664_000385"
     CDS             complement(36458..37114)
                     /locus_tag="VQ664_000385"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HET2788615.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDGHFVP
                     QISFGAGVVEALRPHSKMVFDCHLMVSNPEHHLEDFVRAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTPVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALRDEKGLNFEIEVDGGIDDQTIAQAKEAGATVFVAGSYVFKGDVNERVQTLRKQLD
                     "
     gene            complement(37125..38003)
                     /gene="rsgA"
                     /locus_tag="VQ664_000386"
     CDS             complement(37125..38003)
                     /gene="rsgA"
                     /locus_tag="VQ664_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HET2788616.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDGGELDFYQQTYGDIGYDFVTSKEELLPLLTGKVTVFMGQTGV
                     GKSTLLNKIAPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     TAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGTIAPFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            complement(38596..39369)
                     /locus_tag="VQ664_000387"
     CDS             complement(38596..39369)
                     /locus_tag="VQ664_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HET2788617.1"
                     /translation="MRKKLVNSLMCAVVLSGFPIATYANEKNIGPNITVSNGQTRLSI
                     PEKNGVEVIQSEENRVVYEVKEAAKIETSDGDMVAPIVVDSRITSINNQVVQGKTVYT
                     ADLEKATFVEEGYNKLAKPTNILDHIFGIQKVHAYTQNITTHQSQFDSTYSVELYTVV
                     HWVSYDGGVQKNITKISGGVDFHERDIEIESSSVEVRQGGWYSSQQKWFHPGARSSWE
                     YSTGFSKVGPGENRVVTNYTVNLIRYGDRWSAYLQNNPW"
     gene            complement(40059..40931)
                     /gene="rsmA"
                     /locus_tag="VQ664_000388"
     CDS             complement(40059..40931)
                     /gene="rsmA"
                     /locus_tag="VQ664_000388"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HET2788618.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAEVMAFEIDHRLVPILADTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPDLPIKVVANLPYYITTPILMHLIESGIPFSEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPVPAVAVED
                     ENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLE
                     EFASLADALKGQGL"
     gene            complement(41182..41400)
                     /locus_tag="VQ664_000389"
     CDS             complement(41182..41400)
                     /locus_tag="VQ664_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2788619.1"
                     /translation="MENMTNPLLLVQIRVHGYLLDFASSEGQRQKHYRLKNLPQTVEL
                     TVDDVEEDVDLTLPENRSYQEADFFDTQ"
     gene            complement(41468..42109)
                     /locus_tag="VQ664_000390"
     CDS             complement(41468..42109)
                     /locus_tag="VQ664_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2788620.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRIIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            complement(42111..44141)
                     /locus_tag="VQ664_000391"
     CDS             complement(42111..44141)
                     /locus_tag="VQ664_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HET2788621.1"
                     /translation="MKRLFILISMVLVSLYMVITSVDHREEILFGNYPSVDVTGMMIN
                     QPVASREEVTEVLSHLAVEHNSLIARRIVEPNEAGETLFTYATYGEGELPEGLTISSK
                     ESAETSDLLGSYLIVSGSLDGVSLQTTLKELGYQGFVSNGEDPFSIVLLLAATPMVLL
                     SLAIFLLTFMSLTLIYRIKSLRQAGIRLIAGESLFGVALRPVLEDVRQFICSVLVSSL
                     LGLGILWYQGALFMATVQLVIIALLLYGLTLAGISTLLSVVYLLGLQENSLVDLLKGK
                     LPLKRMMTLMMVGQLLAVLVVGSSATALLPHYREMQEMERASNKWSQSSDRYRLSFGW
                     SSAFADEEGTRKDNREWQTFTEERLANTDSFYIMSNVDNFSDGAEVDLDGNRLSDYTP
                     SGNVIYVSPRYLIEEKITVSSEFMDKMQNLSEGEFGLILPESLREQSTYYQRLFTDYL
                     QNFSSESVEVTSQKYYLPQVSLAFTETGQERFLYNDGYKTTRQYLKDPIIVVLTPQAT
                     GTRPVAGMLWGTTANSALKLDRYGDSITALKEQGLYHKVSYLVKSQLFFAKVLNDKRV
                     EFYSLLIGTILTLSTAILLFDSMNLLYFEQFRRELMIKRLAGMTIYELHGKYLLAQGG
                     VLLLGLVLSSILTRDGLISALVVALFTLNALLILVRQDKKEEAGSMAVLKGK"
     gene            complement(44410..45309)
                     /locus_tag="VQ664_000392"
     CDS             complement(44410..45309)
                     /locus_tag="VQ664_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2788622.1"
                     /translation="MLIGQKIKEIRIEKGVSRPYFCGDEQELTVRQLSRIESGASQPS
                     LPKLAYIARRLGVPVYSLMPDFSALPPAYLELKYQILREPIYGKEEEYDKKEACLEEI
                     YKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMSQIIEKEVYSTNDMLL
                     IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTKLENFFIIRDTLISGMCCLEKVG
                     VTDCFNDYLSCLQEIMDKTQDYQKKPLVFMFLWKQALREERDFSLAESFYQSSKTFAK
                     LIGDGFLVKKLTEEWQEDVKKYL"
     gene            complement(45381..45941)
                     /gene="rnmV"
                     /locus_tag="VQ664_000393"
     CDS             complement(45381..45941)
                     /gene="rnmV"
                     /locus_tag="VQ664_000393"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HET2788623.1"
                     /translation="MKEKISQVIVVEGRDDTVNLKRYFDVETYETRGSAINAQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMTAIPTVRHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLAGADSRKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            complement(45941..46714)
                     /locus_tag="VQ664_000394"
     CDS             complement(45941..46714)
                     /locus_tag="VQ664_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HET2788624.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALAAEMGVTQMNIVGFDKPTIE
                     RALELVDEYDQLYATIGWHPTEAGTYTEEVEAYLLDKLKHPKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIQLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKVTDLQEAAKELPLDKILVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAVATTANAERIFGLDSK"
     gene            complement(47019..47912)
                     /locus_tag="VQ664_000395"
     CDS             complement(47019..47912)
                     /locus_tag="VQ664_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HET2788625.1"
                     /translation="MVAQDPKAQDSTKPTAEKSTVKAPAQRVDVKDITHLTDEEKVKV
                     AILQANGSALDGATINVAGDGTATITFPDGSVVTILGKDTVQQSAKGESVTQEATPEY
                     KLENTPGGDKGGNTGSSDANANAGGGSQAGGSAHTGSQNSAQSQASKQLATEKESAKN
                     AIEKAAKDKQDEIKGAPLSDKEKAELLARVEAEKQAALKEIENAKTMEDVKEAETIGV
                     QAIVMVTVPKRPVAPNAAPKTTSAPQATAGTMQDVTYQSPAGKQLPNTGSASSAALAS
                     LGLVVATSGFALLGRKTRRRK"
     gene            complement(48196..48330)
                     /gene="rpmH"
                     /locus_tag="VQ664_000396"
     CDS             complement(48196..48330)
                     /gene="rpmH"
                     /locus_tag="VQ664_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HET2788626.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
BASE COUNT        13991 a        10914 c         9042 g        14527 t
ORIGIN      
        1 taaagctatt atatcagctt tccagaggag cgacaagaaa cagcaaactt atatatagcg
       61 gaatgaaata aggaaagtca aatcgatttt taacaatgtt ttagaagtag atatgtacta
      121 ttctagtttc gatctattat agttggttga gtttggaata gtacgctgta gctgctaaaa
      181 catttctaga aattaatttg actttcctaa tagagttgtt catatcttat ttcaagctac
      241 tatatataat ctaaaaactt gaatcaaaaa tcgaaaaagt agcggatttc tccactgctt
      301 taacagctta ttcttcaatt tcgatttcaa gttcatcgcc taagtcaagc ggaacttctt
      361 cattcactgc ttcttctttc tttggctcat cttttttgtt ttcagtatct tgttctgaaa
      421 cttcttctcc atcaatcaag ccaaatttag aacggacttg cttatcaatt tcatcaaaga
      481 tttctgggtg ctctgccaag tatttcttag cattctcaga accttgccca attttttcat
      541 ctttgtaaga ataccaagcc cctgcttttt tgataatatc caaatcgctt gcaatcttca
      601 aaagctcacc agtcttagaa attccttctc cgtacataat ttcaactacg gcttccttaa
      661 acggtggagc taccttattt tttacaacct taatcttagt ttctttaccg acattggttt
      721 ctttttggtc accagttccc ttaatttgtg tattaccacg aacatccaag cggactgaag
      781 catagaattt caaagcacgt ccgcccggtg ttgtttctgg atttccaaac atcactccaa
      841 ctttttcacg caattggttg ataaaaatgg caattgtttt ggttttattg atagaggcgc
      901 caagtttacg catggcctgg ctcatcatac gagcctgcaa accaacatgg ctatctccga
      961 tatctccatc aatttccgca cgaggaacaa gggcagcaac tgagtcgact acgacaagat
     1021 caactgcacc tgagtcaatc aattttcccg caatctcaag accttgctct cctgagtctg
     1081 gttgagacaa gagcaattcg tcaatattga caccaagggc cgcagcataa gctggatcaa
     1141 gggcatgttc cgcatcgata aaagcagcaa tcccaccttc tttttgcgct tgtgcaactg
     1201 catgaagggc aaccgttgtc ttaccagatg actctgggcc atagatttcg atgatacgtc
     1261 ccttaggata accacctgag ccaagggcaa tgtcaagagc taaagaacct gagctcatca
     1321 cttgcacctt ttgctccgca cgttcaccca aacgcatgat tgatccttta ccaaagtctt
     1381 tctcaatcaa tttaagagcg tcattcaagg ccttttcacg ttctgcccca aatttttttg
     1441 aaatttcttc taattttttt ggttttttcg ccattctatt ctcctacatt ctaatgatcc
     1501 tcagacctat ctactattat atcaaaaatt agtcacttaa taaagccttg cgaactaggt
     1561 taaaggcatg cataaccgca atgtgacgta catctgctcg gcttctgcct ccaatattaa
     1621 ccttgataac ctcagttcct tgatcttgcg ccaagcctat gaagactgtc ccaactgggt
     1681 gtccttctag gctatctggt cctgccactc cagtcaaact aattccaaaa tcagactggg
     1741 tcttgcttcg tgcctgctca gccatcttct gagctgtaaa ttcagacacc acaccatgtt
     1801 cttccaaatt cttggcagga atatccaaca tccttgattt ttcctccaag ctataggtca
     1861 caaaaccacc cttaaatata cttgaaattc cagaaaaatt cgccacggta gcttggaaaa
     1921 gacctgccgt caaactctct gcagccgcga tggttttccc ttgccttttc agttcttcta
     1981 ccacaatgct ggctaaacta gtttcttccc cataaccata gcaaaagtct cgtaaagaaa
     2041 ttccttcgaa agtctggcag tccaagattt gattttccaa gatatccagc gcttgattcg
     2101 cctcttcttg actgctagcc tttgttgaca gacgtagagt gacttctcct gtcttggcat
     2161 aaggggccaa ggtaggatcg acctgattat caattaaatc agccaaaatc gtaaccagct
     2221 ggctctcgcc aatcccaaag aaacgaagaa ctcgggaata cagcttgctc cctgtcatca
     2281 acttgggtag aagtaggttt aagaccatgg gtttcaattc acttggcgga cctggaagga
     2341 cgacataggt cactccgtct acttctaatt ttcctccaac agccagtcct gtttcgtttg
     2401 gcagtggaat cgctccttct acaatttgag cttgtctttc gttattcggt gttcgggcat
     2461 agtctggtcg cagggcaaaa aagatatcca acttctcctg agcctgagga tcaaagacta
     2521 atgctttccc taaaaattta gctagggttt gtttggttag gtcgtcctca gttggcccca
     2581 aaccgcctgt caaaatcacc agactgctac gttgactggc aatctcaagc aaagacaaga
     2641 gacgaacttc attgtctcct acagccgtct gaaaatatac atctacccca atctcagcta
     2701 gtttttccga caaaaactgg gcattggtgt tgacaatctg tcctgtcaaa atctctgttc
     2761 caacagcaat gatttctgct ttcatgtttc ctcctaccta tctattcgta tttttttgaa
     2821 aaaatcgcag gaattttcct acgattgatt ttttatttgt atcaaaagtt aattatcttc
     2881 atcaccaaca ggtgctctgc caaataaatc ttcaaataaa accgcattgg tttcaagctg
     2941 agtaacttct tcttgtccca aagaacgtcg gagtatattt tgcatttcca acatatgtgc
     3001 tcttgaaaca atctggtaag aaacaccttg aagtatctct ccttcaccct gcaactgctg
     3061 agtttcaatg gttttaaatg aatctttata gcctagcaag ttagggatac tttttgcaga
     3121 caaatcaata ttggtctgca tattgtcact caaagctttt agaatctctt gataatgacc
     3181 aacgctattt aaactgagag ctttttccat gactttttga ataacttcac gttgacgttt
     3241 ttgacgacca taatccccct caggatcttg gtaacgcatt cgtgcataga ctagggcttt
     3301 ttctccccca atatgttgct ccccaacacc gatagaaata gtattaaatt cttcttggtc
     3361 actgatagaa attgggaaac ctaggatatt attgactgta atacctccta ctgcatccac
     3421 tagtttttgc aaccctctca tattgaccat cacatagcga tcaatatgga tattcatcat
     3481 tttttgaatg gtttctatag caagctctgc tccaccatct gcatatgctg agttcagttt
     3541 cgcttcatga gcctgaccat tccctgattc aatgcgcgtc agaatatccc gctctaaact
     3601 catcattgtt gtttttttcg ttttaggatt cactgtcatc aagatcatgc tatcacttct
     3661 accgacccaa gtttcagttc gttcaacatt tccggtgtcc actcccatta acagaatggt
     3721 tagaggttca gtcgcttcaa taaccttggt ttcttcgccg atttttttat aggttttagc
     3781 taaggtttct gtcccttgtt gataaatagt ataagcaaaa acacctactc ctactacagt
     3841 tacagaaagt aaagctagca ccattccaat aattttttta accatatttc tactaaccta
     3901 tcagtttacc catcaagtaa acatcgataa atttcccttc ttctatatat gccccacgct
     3961 cttggctacc ttcaatgaca aagccatgct tttgataaag atggactgct gcttgattac
     4021 gagtttggac agtcagttgg agacgacgca gaatgccact tgcttgtgcc cactctatcg
     4081 cttcttctag caacaaactt cccaagccat tattccaata tctttttcca atcacaatga
     4141 agagatctcc aatatgacgg actctcttac gctgatcagc tgtaatattt acaataccag
     4201 caattttgcc atttaagaat gcaagtaagg ttatctgatt gtccgaacta gcttgcttgt
     4261 tgaggaatat ttccatctcc tcactagtca agagaatacc atctccgtct aggctggtaa
     4321 agtctgtctc caaactcaca cgatttaaaa aggccactaa ttcagctgca tctttgggct
     4381 ctgcttccct aatgagcaat tcatactcca tattgaagct cctctaacaa tttctcagca
     4441 cgcaaaccct ttgcctgaaa atttaaacgg cgtccatctg cttcttttag aatttccaat
     4501 tctaaataag catctggcaa ggcatctcct aagagatttc cccactcaat aacagtcacg
     4561 ccgccaccaa agataaactc atccaagtcg atagaatcag catctccttc aatacgataa
     4621 acatctaggt gataaagtgg aagtcgacct tcatactctc tcacgatagt ataggtggga
     4681 cttttaatca tttgagaaat ctgtaatcct tttgcaagtc ctttagtaaa ggtcgtttta
     4741 cctgcaccca gttctccagt taagattaaa acatcattct ttgctaatag atggcccaaa
     4801 cgctccccta aggcttgcaa ctcttcttca ttttttgtgt acatactctt attataccaa
     4861 aaacttttct tttgtgtcta ttttcctact aaacttatca tcataacatc cataaaaaac
     4921 aggctttctc taaaagaaaa tgagcgtaac aatgaccaat acaagatctc ggaaaatatg
     4981 accataaaag gaaacttcct tcttaaccga atttgggaca agataggctg caaaaaacaa
     5041 gcccagtcca atataaatca gaagtgagac aatggtcatt ggatttctta agaaaagaag
     5101 tgttgctaaa atagtcacca acactgtctt ttttctgtct agcatagcaa gaaaatcgcg
     5161 cacgtatttt ttcaagggta aaaaaatcag caaatctagc ccaaatagga aaaagaagga
     5221 tggcaataaa aagtcaacta attcttgctg cagcgtattt ttgatgaaca agttatctga
     5281 caaaacaaga acagctccta acaaattaat taagagtaac atactgtaaa aaagcttcac
     5341 cgacttctta ctggctagga cactatggac ttcttgctta cgggtataaa gataatttac
     5401 tccagcacag attcctgaaa cgaaaaccat gctcccgatg aaaaaagctg tactttgttt
     5461 aaaggacaag atgcattcct tccataggaa acagctactc aaactgattt gaattaaagc
     5521 taacaaaaat aagattctca ttgatttcat cttctctctc ccttcctacc aatcattata
     5581 ctaggagaaa agagagaact gtttctaatc ttctcaaatg tctctttaag acgctaaaca
     5641 aacactagag actaatactc aatgaaaatc aaagagcaaa ctaggtagct agccacaggt
     5701 tgctcaaaac actgttttga gattgcagat agagctgacg tgatttgaag agattttcga
     5761 agaatataaa tttgaaatca tgaaaatccg tcaaacgggt ggttgttttg tctcgcacct
     5821 cacggagcga gacggactca gagtcacata attataaggc tgatagtatt aatctaacta
     5881 tcagccttac aggttattta acgtttcaga aaaactataa tgtcaagatt aactaaacag
     5941 tatctaattc cttcaaataa ttttctatct tcatcagcat taaaggattg ttataaatct
     6001 tgcatagctc tcttgcttct atataataat ttttgacttg ttctctgtct agaaatttgg
     6061 ctccagcatt tcctacaaga ataagtagag gagccaattg gtagcttgtc tgtctttgtt
     6121 tacagagttc gatagtctca agagcttctt ggatggcttc attatatttt tcctttgata
     6181 ctaggtagtg agcgtaattg taacgaactc tgatgtagcc aaataaaaac tcttgatgct
     6241 caaaattttt tgtctgatat aactccatca aatgagagta gtttacctca tattcttgtt
     6301 cacgacccac taaggaatag aaattagata gagtattcaa cgcctttaaa taaatcaaag
     6361 tatttgagga gacttttaat aatatatttt ccaatgaaga aattgcttca cacttactgt
     6421 catattgaca gaagtcaata atagctttaa tccattcaag gtaagttcgg tcttctagtg
     6481 ttagaaaagt acttcgttca atctctattc tataaatata ttccaaattt tcataatttc
     6541 tatcatctaa taggcgagca gataattgct tgaaattaga gaggttagat ttaatttcaa
     6601 tttgttcatt aaaaaaataa tctaatggca cttcgagtcg ttgtgagagt ttgaacaaaa
     6661 ggtctgcgga gggaatgaaa taccctctct caattttact aatctggctc tattcacaaa
     6721 ttccttctgc aagagtttgt tgggagagtc tcaactcttt tcttttcaat ctgaatttct
     6781 ctgcgagtgt attcattaaa gataataaac cttcctattt gcttaatttc attataaaat
     6841 ttttagttca aaatagcaag ttaaaggaat aaataattct ttgcggtaat aaacaaaaaa
     6901 aagtcaaaaa ttacataaaa atgcttggct aaataaaata tatttgttaa aataaggata
     6961 atgaaaaaga aaagggtttc acgaatgaag aaaaatcgtg gaattcaaaa attagctata
     7021 ttagtattac taggtgtttt tatgtttagt aacacaattc cttaccaaca gtttattcag
     7081 aagaatagac aattggagat tcgagtccaa tcgcaaaaga agtccaatgg tcttgatgtt
     7141 gggaaggctg attgatttta tattacttta aaattcaact atttagagaa aggtattctg
     7201 atgagagctt gtaacaatac cagatagata taagaatgga gatgtttgat aaaatgcttt
     7261 catagctaac caactgttga aaattatgag ttacaaaatc taaagtattt aagattggtt
     7321 tataaaatta ggtctctgcc tgtagaaagg aacgtgcagt tagaaaggag gaaaaaatag
     7381 gatactataa ttcagactga gatttctaat taaaatatat agttgcattt cgctcatttt
     7441 cataatattt cattcagagg agtaataata tgttaaaatt tagaaaagta gttgcatcat
     7501 cccttgccgt tttggcattt agtttggctc ttcctgtttt ggcagtttct caccgtggtg
     7561 gcgagtggac ctatggaggc catcatgatc caaataattg gggagcattt tcgaattatt
     7621 atcatggttc acagtatcac tgggcctatg ttggaagtaa tggacgtaac aatcaaaaaa
     7681 cagtttatgc aggagcacgt agtgcggcct atgcgtttgt taatacaaat tttggggagc
     7741 aagttacatt tgatgcggga tggtaaagaa taattgaaga agattctttt atcaatagtt
     7801 cagtaagctt gttagtttat agagggcagg ggtatttctg ccctctgttt tagaataagg
     7861 aatgcactat gaaaaaatta tttatactca tatccaacct gcttgctagt ttgttctttg
     7921 tttgggtatt taccatttgg actgatacat atgtctccta ttattacccc aacgttgttg
     7981 tacatgattc ttcccctgaa acaacttttc agcatgttgc tacacgcttg gaaaaactag
     8041 cagaagaaac agatagcttt attgcgattc aacaccaaga tcctaactca gaaggtacta
     8101 cagttttttc ttatacgacc tttggggacg gaaagttgcc tgatgggctt caggaaaaaa
     8161 aactagaaga tgctcaaagt agtagtgttg aaacaaacta ttttgtattc gatggacacc
     8221 tagatattca cttgctaagg gaggagctaa gtcaacttgg cttgactaac atgaacctga
     8281 caattccatc taaactatct acgttaatgg ctatctttag taacggattt cagttaatca
     8341 gtctattgat tttcatctta acctttatag cactgacttt aattagtcaa attagccaat
     8401 tacggtcgtc gggcattcgc ctcatttcag gagagaaacg gtggtccatt ttccttagac
     8461 cagttggtga ggatttgaaa gggatagctg ttggtttcag tttagctggc gtgctcgcca
     8521 ttcttatgca aaaaattctg tcgcttccaa cgcaatccct aatgaccata ggagcaggct
     8581 tgctcagtta taatctcatc ttgttgtcga tctccctgtt tttcgctcaa ctcttcgcag
     8641 ttgggataaa aaagatacac ctgatgcaga ttataaaagg gcaagtgcct gtcagaggaa
     8701 tcattagttt gattttaatc ggtcaactat tagcgattat tattgtaacg ctgggaatag
     8761 ggagtagctt aaagtattcc caagcctggc aacagcatcg gattggacaa gaggcttgga
     8821 gtcaggaaag gcaactgatt accctatcaa tcagccgtga aggaacgagt cctggttttg
     8881 atgaacaagc tcaaaggaaa ctcagaactt ggtatcaatt gatggatctg gctgtttcag
     8941 aacaaaaggc tttcttatct agacaccagt taattgaccg tactttgcaa aatggcatgg
     9001 cttcctccaa aaacttgata acctctacag aatggcacga ttacaacccg aatggcaatg
     9061 tccttatcgt cacaccgcaa tacttggagc gtcaaaacat tcctgtagat acaactattg
     9121 agcaaaagat gaatcacctt gatgtagggg agtttgtctt attgctgcct gaacacctcc
     9181 gttcagagga agaacattat aaatctgttt ttgaagacga cttaaccagt cgcatgtcta
     9241 gtcaagatga acgacagcaa atgactgcta cggtaggtta tttagaatca ggtcaggatc
     9301 gttttgtgta taatacgacc cctatttctt accagcagtt tttgaaagat ccaatcatca
     9361 ttgttataac accccaatca actggtccac agtccatttt gttttggata gacgcagtac
     9421 agaactacgt tctctttaat caattgtctg atgcccagga gcttatccag agacaaggca
     9481 ttgaaaattg ggtctcagaa atgcaaacag gttaccacaa ctacatcaca ttattggata
     9541 atattcagag ggaacgttgg gtaatgctag caggagctgg gcttgggatt gcaacttcaa
     9601 tcttgttgtt taacactatg aataggctct actttgaaga atttagacgt gccattttta
     9661 tcaaacgcat tgcaggtctc aggttcttag aaatccatcg cacttatctc tttgctcaac
     9721 tgggtgtgtt tttactggga tttgttgcga gtgtatttct tcaggtagag ataggagttg
     9781 ctttcttagt cttgttactc tttactggtc tatctctttt acagttacat gtccaaatgc
     9841 agaaagaaaa caagatgtcc atgcttgttt tgaagggagg ttaatatgat tgaacttaaa
     9901 caggtgagta aatcttttgg agaacgagag ttattttcga atctttcaat gacatttgag
     9961 gctggaaaag tctatgcctt aattggttca agtggtagcg gaaaaacaac cttgatgaac
    10021 atgattggga aattagaacc ttatgatggg acgatttttt accgaggtaa agacttggcc
    10081 aattataaat cgagtgattt tttccgtcac gaattgggct acctcttcca gaactttggc
    10141 ttaattgaaa accaaagtat tgaagaaaac cttaagctag gtctcattgg tcaaaagttg
    10201 agtcggtcgg aacagcggtt gaggcagaag caggctttag aacaggtcgg cctgacttat
    10261 cttgacctag ataagcgcat ctttgagtta tcgggcggag aatcgcaacg ggttgccttg
    10321 gcaaaagtta tcttaaagaa tccacccttt attctggcag atgagccaac agcttcaata
    10381 gacccagcaa cttctcagtt gattatggag attctgctat ctcttcgaga tgataatagg
    10441 ctaatcatta tcgcaacaca taatccagca atttgggaga tggctgatga agtgttcacg
    10501 atggatcgtc tgaaataaaa atccttgttt ttaattgcac gatgagttac tgaaatatta
    10561 tcatgaatca ataattggag ttaatttaga attgtacttt attaatattg aggtaacttt
    10621 ttcttgataa aggaagaaat agtggagagg aagttagaat gaaaaaattc gacaattata
    10681 ttgttgagaa gccttgcgat tctaattcag ataaactgca aaaaatctta ataattgaaa
    10741 atttggtaga tgatattttg caatttcctc tcagaatcaa taatagtgta ggagagattt
    10801 tcctcctaca accgtttcaa aagaaaacta tctttattcc atgttatttt gaggaagata
    10861 ttgtgaaagt caaagatgat gataaagttg agtggaattt gttagaattt caaaaattta
    10921 gagcattttt ggcttagtaa tctgtgttga aggctcaaaa cctatggtaa aaaagtcgct
    10981 ttgaaaacgt attgcctcca aagatttagt taaataatga tttaacacaa aaagaaatta
    11041 ttgaagttct ggaaagatgt tgtttcagta ttgagaaaag gtgggaaaaa cttgcgattt
    11101 tcacagagaa aggaagaaaa agtatagaaa tatagtcaat tgaaacaaga acaggacaaa
    11161 agaacctttt gtgccatatt tttctccttt cgctttacaa ttggcttgaa cacctttatt
    11221 gtatcgcgtt tggagttttt ttggtataac cttcgacgcg cacccgcata gcgggtgttt
    11281 ttttgtctcg cacctaacgg agcgagacga actaatagtc acttaatcaa aaaacgcacc
    11341 atatcaaaaa ctaaaaagtt tgatatcatg cgtcatgtct taaactaatt gactatactt
    11401 tctattcaaa tgagctttta accaattgat tgagccaatc cactcttaaa accaaagagc
    11461 aatttctcgc ttagctgact cttctgaatc tgaaccatgt acaacatttt ggataacctc
    11521 attttctcca gcagcttttg caaaatcacc tcgaatagtg cctggtaaag cttcttctgg
    11581 acgagttgca cccatcatgg tccgccaagt ttcgattact ttgggaccag aaatgacacc
    11641 cacaagaact ggacctgaag tcatgaattc acgaatcggt gggtaaaaac tctgaccaac
    11701 caagtcctga tagtgctggt caatcaactc ttctgaaact tgtgaacgaa actccaattt
    11761 ttcgattgta aatccacgtt gttcgatgcg ctttaacact tcacccacta gccctctttt
    11821 tacaccatct ggtttgatga taaagaatgt ttgttccata cccgtctcct ttgtcagctt
    11881 ctttctttta ttttaccaca tttcgtggaa aaatggagaa agttttcaga atagagaatg
    11941 agagaacccg agggttctct cattctctat tattctactg tttcttccac agtttcaacg
    12001 gcagtatcca caactacttc tgttgtttct tcatttcctt cttcctctac tggaggatta
    12061 aggtattctt cttcgttgac agcatatggt tcaaggttac ggtaacgggc cataccagta
    12121 ccagctggga tgatcttacc gatgataaca ttttctttaa gtccaaggag atggtctttc
    12181 ttaccacgga tagctgcgtc agtaaggaca cgagttgttt cctggaagga agccgctgac
    12241 aagaaactgt ttgtttcaag tgaggctttg gtaattccca taaggactgg gcgacctgtc
    12301 gctggaactc cacctgcgat aaggacatct ttgttggcat ctgtaaagtc attgatatcc
    12361 atgagggtac ccatgagaag atctgtatca cctggatcca tgacacggac tttacggatc
    12421 atttgacgaa ccattacctc gatgtgtttg tcaccgattt ctaccccttg gctacggtaa
    12481 actttttgta cttcaccgag aaggtacgtt tcaactgaca agacatcacg aactgcaagg
    12541 agacgttttg gttggataga accttctgtc agagcagcac cacgcgctac ttggccccca
    12601 acttcgacac gcatacgagc tgtaaatgga acgacatatt caccttcgcc agtttcaccc
    12661 ttaacaaaga ctttcttggt acgagttgat gcatcttctt cgatagcagt aacttctcct
    12721 ttaacctctg tgataaccgc ttccccttta ggattgcggg cttcaaagat ttcttggaca
    12781 cgaggaagac cctgagtgat atcggtattt gaggcaaccc cacctgtgtg gaaggtacgc
    12841 attgtaagct gtgtaccagg ttccccgata gattgggcag caatggtacc aactgcttca
    12901 ccaacttcaa ccgcatcacc agtcgccaag ttgataccgt aacagtgacg gcagacaccg
    12961 tgacgagtgt tacatgtaaa tacagaacgg atagtcactt cttccacacc agcattgaca
    13021 atttcacgcg ccttgtcttc tgtaatcaat tcatttggac caataatcac tgcaccagtt
    13081 tctggatgtt taacagtttt cttagtgtaa cgaccgttga gacgctcttc gagagactcg
    13141 atcatctctt ttccttctgc gatagaacgg atcaagagac cacggtcagt tccacagtcg
    13201 tcctcacgga tgataacgtc ttgggcaacg tcgaccaaac gacgagtcaa gtaacctgag
    13261 tcggctgtct taagggccgt atcggtcata cctttacgag caccgtgagt tgagaagaac
    13321 atttccaata ccgacaaacc ttcgcggaag tttgaaagga ttggcaattc catgatacgt
    13381 ccattcggag cagccatcag accacgcata ccggcaagct gtgagaagtt tgagatgtta
    13441 ccacgggctc cagagtccat catcataacg attgggttct taggatcttg gttagcaatc
    13501 aagcgtttct caagtttttc acgggcagca cgccattcag ctgtaacagc attgtaacgc
    13561 tcgtcgtctg tgatcatacc acgacggaat tgtttggtga tttgctcgac acgtttgtgt
    13621 gattcttcaa tgatttcagc cttgtcatca acgactggga tatcggcaat acccactgtc
    13681 aatcctgcaa gagttgagtg gtggtaaccg agattcttca tgcggtcaag tagggcagaa
    13741 gtttctgtcg tacggaaacg tttgaagatt tcagcgatga tatttccgag gtttttcttc
    13801 ttgaacggag ggttgagctc aagattgctg atagcttcct tgatatctcc accaagtggc
    13861 aagaagtatt tagctggaac accttctgtc aagttggcat tgtttggttc ttgcaagtat
    13921 ggtagcccct ctggcatgat atcgttgaag agaattttac caactgttgt aagcaagacc
    13981 ttatgtcttt gctcttctgt ccaaggcttg ttgaggctgt ctgttgcgat accaacacgt
    14041 gagtggaggt gaacataacc attgcggtaa gccataaccg cttcgtcacg gtctttgaag
    14101 accattcctt caccttcgcg accagcttct tccatggtca agtagtagtt acccaaaacc
    14161 atgtcctgag atggagtaac taccggtttc ccatctttcg gattcaagat gtgctcagca
    14221 gctagcatga ggatacgagc ttctgcttgt gcttcttctg aaagtggtac gtggatggcc
    14281 atttggtccc cgtcaaagtc agcattgtag gcttcacaga caagtgggtg caagcgaaga
    14341 gccttaccat caatcaagac tggctcgaag gcttggatac ccaaacggtg aagggtcggt
    14401 gcgcggttca aaagcactgg gtgttcttta atcacttctt caaggatatc ccagatacgc
    14461 tcatctccgc gttccaccaa gcgtttagct gctttgacgt tttgcacgat atcacgggca
    14521 acgatttcac gcatgacaaa tggtttaaag agttcaatcg ccatttcacg tggcacacca
    14581 cattggtaca tcttaagagt tggaccaacg gcgataacgg aacgtcctga gaagtcaaca
    14641 cgtttaccga gcaagttttg acggaagcgt ccttgtttac ctttaagcat gtggctcaat
    14701 gatttcaatg gacggctacc tggtcctgtg attggacgac cacgacgacc attgtcaatc
    14761 aaagcgtcaa ctgcttcttg aagcatacgc ttctcatttt gaacgatgat acctggtgca
    14821 tttaactcaa gcaaacgagc caaacggttg ttacggttga taacacggcg gtaaaggtca
    14881 ttcaagtcag atgaggcaaa acggccacca tccaactgca acattggacg aagatctggt
    14941 gggataaccg gaagaatgtt aagaatcatc cattcaggtt tgtttccaga cttgtaaaag
    15001 gcatccaaaa catccaaacg acggatggct ttgacacgtt tttgtccagt agctgttttc
    15061 aattcttctt tgagttcagc aatttctttt tcaagatcta cttgcttcaa aaggtcttgg
    15121 atggcttccg cacccatctt ggcaacaaat gaaccataac catattcacg caagcgctct
    15181 cggtattcgc gctctgtcat gatagacttg tgctcaagtg gtgtatcctt aggatcaatc
    15241 accacataag ccgcaaagta gataacttcc tcgagggcac gagggctcat atcaagggtc
    15301 aagcccatac ggcttggaat ccccttgaag taccagatgt gagatacagg agctttcaat
    15361 tcgatatgtc ccatacgctc acgacgaact ttcgtacgcg ttacttcaac cccacagcgg
    15421 tcacaaacaa ttcctctgta acgaatgcgt ttgtacttac cacaagcaca ttcccagtct
    15481 tttgtaggac caaagatcac ttcatcaaag agtccttcac gttctggttt caaggtacga
    15541 taattgattg tttcaggttt tttgacttct ccataagacc atgaacggac tttacttgga
    15601 gaagctaggg tgatttgcat acttttaaaa cgatttacat caaccactat ttcttccctt
    15661 tctattctaa gtgaactgct tattcttgtt cagcagcttc ttctgttgct tccgcttttg
    15721 ttgctttctc agcttcttca gcttcaaagg ctgctttagc ctcttgagct gctttttcgc
    15781 gggctttttc aaggtcatct acgtggatga catcttcgtc cattccttca tccaagtcgc
    15841 gaagttccac ttcttggtca tcttcgtcta ggacacgcat gtcaagacca agagattgca
    15901 attctttgac aagaactcgg aaggattctg gaacacctgg ttttggaatt ggtttgcctt
    15961 ttgtaatagc ttcataggct ttcaaacgtc cgttgatatc gtccgacttg taagtcaaga
    16021 tttcttgaag gacatttgac gcaccgtagg cttcaagagc ccaaacctcc atctcaccga
    16081 aacgttgtcc accaaactga gctttacctc cgagtggttg ttgggtaaca gttgagtaag
    16141 gtccgactga acgcgcatgc aatttatcgt caaccatgtg gtggagtttg atcatgtaca
    16201 tgactccaac agaaacacgg ttatcaaatg gttcacctgt acgtccatcg taaaggattg
    16261 tcttggcatc gctatccata cctgcttctt taacagttga ccaaagatct tcagaacttg
    16321 ctccatcaaa gactggtgtc gcaatgtgaa taccaagagt acgagctgcc ataccaaggt
    16381 gaagctccat aacctgaccg atattcatac gtgatggcac cccaagtggg ttcaacatga
    16441 tgtcgactgg agttccgtct ggaaggtaag gcatgtcttc tacaggaacg atacgagaga
    16501 caaccccttt gtttccgtga cgtccggcca ttttatctcc gaccttaatc ttacgttttt
    16561 gagcgatgta aacacgaacc aacatgttaa cacctgattg caactcatct ccatttacac
    16621 gtgtaaagat cttaacatca cgaacgacac catcggcacc gtgtggtaca cgaagagaag
    16681 tatcacgcac ttcacgagac ttgtctccaa agatagcgtg caagagacgt tcttcagctg
    16741 aaagatcttt ctcaccctta ggtgttactt tacctacaag aatatcacct tctttaacct
    16801 cagcaccaat acggataatc cccatttcgt caaggtcttt gagggcatct tcaccaacgt
    16861 ttggaatttc gcgagtgatt tcttcaggcc caagctttgt atcgcgcgtt tctgattcgt
    16921 attcttcaag gtgaacagat gtgtagacat cgtccttcac caagcgttcg ctcatgataa
    16981 cggcatcctc gaagttgtaa ccttcccaag tcatgtaggc aacgattggg ttttgtccaa
    17041 gcgccatttc tccattttcc atagaaggtc cgtcagcgat gaaatcgcct ttttcaacga
    17101 catcaccaac ttttacgaga gtgcgttggt tgtaagcagt acctgagttt gaacgacgga
    17161 atttttggat gtggtaaaca tccaatgaac catcttcacg acgaacttct accttgtcag
    17221 catctgcgta agtaacttta ccatcatact gagcaatcac agccgcacca gaatcgtggg
    17281 ctgcttggta ttccatacca gtaccaacgt aaggtgcctg aggattaatc aatggcacag
    17341 cctgacgttg catattggct cccatgaggg cacggttgga gtcatcgttt tccaagaaag
    17401 gaatacatgc tgtcgcaacg gcaactacct gttttggtga aacgtccatg tagtcaacaa
    17461 tattagctgg atactcttgg ttgacccctt ggtgacgtcc catgacaatc ttctcagcaa
    17521 aggttccatc ttcattcaga ctagagttag cctgagctac agtatattca tcttcttcat
    17581 cagctgtcaa ccaaacaatt tcgttcgtga caacacctgt ttcacggtca accttacggt
    17641 atggtgtttg aacaaaacca tatttgttca agtgtccgta agatgacaag ttattgatca
    17701 aaccgatgtt aggtccttca ggtgtctcga ttggacacat acgaccatag tgagtgtagt
    17761 gcacgtcacg tacttcatat ccagcacggt cacgagtcaa accaccaggt cctaaggctg
    17821 acaaacggcg tttgtgagac aactcagaaa gcgggttgtg ttggtccatg aactgtgaca
    17881 actgtgatga accaaagaat tctttaactg cagctgttac aggacggata ttgataattt
    17941 gttgtggtgt caagacttca ttgtcctgaa cagacatacg ttcacggaca ttacgttcca
    18001 tacgagaaag tcccaaacgt acttggttgg caagcaattc accaaccgca cggatacgac
    18061 gatttccaag gtggtcgata tcatctacac ggccaagtcc ttcagccaag ttgaggaagt
    18121 agctcatctc agcaaggata tctgcaggag tcaccgtacg aaccttgtca tctgggttag
    18181 cattaccaat gatcgttacg acgcgatctg gatcagttgg agcaacaacc ttgaattttt
    18241 gaagaacaac aggctcagtc acaacggctg catcgtttgg gatgtagaca atcttgttca
    18301 agtcgccatc caaatggctt tcaatgcttt caatcacgct acgagtcata atcgtaccag
    18361 cttctaccaa gatttctcca gtttcagggt ctaccaatgg ctctgcaatg gtttggttga
    18421 gcaaacgtgt tttaacattg agttttttat tgattttgta acgaccaact gctgccaagt
    18481 catagcgacg tgggtcaaag aagcgagcca caagcaagct acgtgagctt tcagctgtct
    18541 taggctcacc tggacgaagg cgttcgtaaa tttctttcaa ggcttcgtct gtacgagagt
    18601 ccattggatt cttgtggata tctttttcaa cagtgttgcg aaccaattcg ctgtcaccaa
    18661 agatatcaaa gatttcatca tcacctgaga aaccaagagc acgaaccaag gttgtaaatg
    18721 gaatcttacg agtacggtcg atacgagtgt aggtgatatc ttttgagtcg ctttcaagtt
    18781 ccaaccaagc tccacggtta gggataacag ttgaaccata gcccacctta ccatttttgt
    18841 ctactttgtc gttaaagtaa acacctggtg agcggaccaa ctgagaaacg ataatacgtt
    18901 caccaccatt gatgatgaaa gtacccattt ctgtcatgat tgggaaatca ccaaagaaaa
    18961 cttcttgggt cttgatttcg cctgtttctt tattgatcaa gcggaaggtt acaaaaattg
    19021 gtgctgagta gctagcatcg tggatacgag cttcttctag cgtgtatttt ggttccttga
    19081 tttcatatcc aacaaattcc aactccattg tgtctgtgaa gtttgaaatt ggcaatacat
    19141 cttcaaacac ttccttaaga ccgtggtcta ggaaagcttt gaatgagtca gtttgaattt
    19201 caatcaaatt tggtaagtca agaacttctt tgattcttga aaaactacga cgggtacgat
    19261 gtttcccgta ttgaacgtca tgtcctgcca agatgattct cctttgtaaa taagttccaa
    19321 gccttgtcaa tcaggctttt ctaatcgcca tatggttgta aaccccttat caccgtgtcc
    19381 tcttgacgaa ttttcagaat ctttaagcct ctgttacaaa tgctcaaaat cttgaaaaaa
    19441 agcacaaaaa gagcagctaa atctgacttt ttcagaagat ttaactgctg tgagccttgt
    19501 ctggacaata tttcagacaa aacctacgac aaatgattac ccatattata ccctatttag
    19561 ctagattttt caaggggatt cagtaggttt ttggtaattt ttttcccata gaaaacttgg
    19621 catcacattc gaatcacgct atggtacaaa aaactgaaaa aactattgac tgaaaatcat
    19681 tttcaaggta taataataaa cgttaaggcg gtatagccaa gtggtaaggc acggctctgc
    19741 aaaagcttga tcgtcggttc aaatccgtct accgccttct ataacttgat ttatcaggtt
    19801 tcaaatgaac agaaagccca atttgaaggg ctttttttat tttccctcga ataaatacgt
    19861 ataactttaa aaacttttgg agcgagtttg tggcagagtt ctttccatgg cataattccc
    19921 ttttgaaatc aattgaaaaa agcttcgtca cgcctggtga caaaagcctc tagtttattc
    19981 tgtttcttct tctatttcga cttctgtgat ttggactttt accttggtaa cacgtccatt
    20041 cttcacttta tcattggtta agataaactg tttgttttgg ctgaccaatt catagctgag
    20101 tttctcagtc gttggaatgg ttcccactcc tgtcaaataa taaccagcga tagtatcaac
    20161 gtcatcactt tccagttcaa cattaaagta attattgaaa tcattgaggg tcatagttcc
    20221 ttgaacaatg taggtatcct cgccaatctg atgaacatct attgctgctt tgtccgtttc
    20281 atcatcaatt tcaccaacaa tttcctctaa gaggtcttcc aaagtcacca aaccagccat
    20341 accaccgtat tcatccagca agattgccat ttgtctttgg gtatttcgca gttcttttag
    20401 caagtcatcc acaaaaatag tttcaggtac aaaaagtgga tcttgtaaaa ttctcttcca
    20461 aacaatattg tcaaaaccgt ccacaaagcc tgccttaagg agactcttgg tgtgaatgat
    20521 tccaattaca ttgtccttat ccccatcata aaccgggata cgagaataat tttgttttaa
    20581 aatactttgg ataatggctt gactatcatc ctgaatatcc accataaagg catccgttcg
    20641 aggaaccata acctctcgtg ccatcagttc atcgagcgaa aagacacctt gtaacatctc
    20701 aatctcatca gcatccaatg tttcttcact atttgtcagc atataggcaa tttcatcacg
    20761 ggtcatcttt tcatccgcat catcgaatga cataggagtc aaatggctca agaaattggt
    20821 cgaagcagct aaaagccaaa caaaaggact gactagtttt ccgatcccaa tgataaccgg
    20881 cgctgtacga attgccaagg catcctttag attaagagcg attctcttag gatataattc
    20941 cccaaaaacg atggaaatat aggtcaaaaa tgccaaggat agaaaagttg ccacggcttg
    21001 tgctgtttcg ccattcccaa gccaagaggc aatcacacgt cctagagtat cagttaaact
    21061 cgcccctgat aagattgtaa tcagggtgat tcctacctga atggttgata aaaagtggtt
    21121 aggattttct agtaccttca gcaggcggat gtagcgtctg tctccttctt ccgccttttg
    21181 ttcaactcgg gcacgattaa gagaaaccat ggccatttct gtggctgaga aaaaggcatt
    21241 taataccgtc aagataaaca ataaaacaaa ttgtagcaac aaattctgac tacttgggtc
    21301 ttccatagtt cttctcctaa aatagtatct tatcctttat tatatcacaa aatttaatcc
    21361 aatacatatt atttttttct tagcgtaact tccatctctc tcccaaaact ggaagttagt
    21421 ctaagacgga tttccactga tttcacgcgt ttttctcata ctaaaagcta ggttgtggga
    21481 aactggaagt tagttttaga agttactatt ttttcttagt acctgttcta gccctgctta
    21541 aactagtaaa aagaactcct acatccataa gtgacatagg agtttaggct tatcttttac
    21601 tgagttacag ttacttctcc agttcggtaa tccagttgaa gtcccttttg aacattggga
    21661 actagaacat tgaattccaa ttctccatcc gaagacttgg cttcaatctg tgaagctgag
    21721 ggaactaaat cctcgtttga agcgtagtaa agggttacac ggtaacggac acgcttgttt
    21781 tggtccaagg ctttacgcac cttgctttca tagtagtttt gaccagtcga atactcggct
    21841 tgtgcctgat ttgcccaggc tgtctgaaca gcaatgtttt taggattgct tgttgaggca
    21901 tcaaaaccat ccaaaccacc gattaaggca tagcctaaca aatgacctct atcgactgca
    21961 tgggtataag agccctttag attcttgacc tgatgccaac ctggaggagt ccaagaagtt
    22021 gaaccattcc cagtttcttt acgattcttg tactgacgag tggccttaga caagagggca
    22081 ttagctacgg ttggaacagt ttccttaccc actgtctttg ttttattgtc agcgtagggc
    22141 ttacttgaaa ccttggcatc tagatttgtt ttattaccat tgacgataaa agcacctgag
    22201 ccattccact ccagactccc ctttatttga ctcttgactg cgtctgttaa gacactctct
    22261 gccaatgctt gactaggagc ttcaggcgct tgttttttct gactaagctt ggttttagga
    22321 ctattagctg tcgactgcat ctgcttgata taatagctcc ctgtagacaa aagcaataac
    22381 actagcagtc cgattagtgt ctgtcttgtt tttttgttca tatttctcct tatctttaga
    22441 aaaaggctgg ttctccagcc taatttcctg taaatttatg aatcaattcc tgccattttg
    22501 ctggagacag gatagcccat gaatcttgac ccttgcccaa gattccataa cctaccatta
    22561 aaccgattcc tagagccaga gtacctaaaa tcagtactat gatgactaaa agtaaacgct
    22621 tgactacgta gcttgatttc ttattcatct tcatcacttg cctcaatccg ctgaatctta
    22681 gcacctagct gcgccaactt ctcatggaaa ccgtagtaac ctctatccaa gtgaaccaat
    22741 ttaccgacca cagtttctcc ctgtgctacc aaacctgtca aaatcaaagc tgcactggca
    22801 cgaaggtcag ttgaaagaac ttctgctccc tgcaaaggct gtccaccaac aatacgagct
    22861 gtatcacgga taatctcaga atgcaagccc atgcggcgca tctcttctag gtgttggaaa
    22921 cgattttcaa aaactgtctc caccatggtt gattcgcctt ttgcaactgt catcaaggct
    22981 gtaaattgag cctgcatatc tgttggaaat cctgggtggg gcaaggtttt cacatgaaca
    23041 gcttttagat tttccagttg agaacgaaca cgaattcctt cgtcttcttc aattacttca
    23101 acacccattt caagtaactt ggcaatcaag ggacggttgt gctcccagac agcgtctcga
    23161 atcaagacat caccaccagt catggcagca gctaccataa aggttcctgc ttcgatacgg
    23221 tcctggacta cattgtgagt cgtaccatga agtttctcaa caccagtaat ggttatagtc
    23281 tctgtaccag cacctttgac cttggctccc atttcattaa ggagaatggc taagtcaaca
    23341 atctcaggct cacgcgcagc attctcaatc actgtcaccc catcagccag agtcgctgcc
    23401 atcatcaagt tctgcgttgc accaacactt ggaaagtcca tatagatatg agcaccatgc
    23461 aagcgttctg cctttgcttc gatgtaacca gctgtctgac taatcttaac ccccatagct
    23521 tccagacctt tcaaatgaag atcaatagga cggctaccaa tcgtacaacc acctggcatg
    23581 gataccttgg catgacccac acgggcaagg attggcccta atacaacgat ggaggcgcgc
    23641 atcttactga catacttgta aggggcttcc tcagtgatgt cgccagtagc atccaccttg
    23701 acaagatgag cttcctcatc aaagtcaacc ttggcattca aaccaccaac tacctgattc
    23761 ataataaaga catccgacaa aatcggaaca ttctgcaaga cggtctttcc ttcacttgct
    23821 agaatagtcg ctgccaacaa gggtaagact gcattttttg ctccctcgat cgtcacgctt
    23881 cctaccagac gattatcgcc accttgaacc acaattttat ccatactcgt ttcctttact
    23941 cttgatttta taataatcct ctaagcgctt cttgccacaa atgatacagg ctaataaaga
    24001 aagaactcag gatgtagcct atgacaatgc taaaaaaggc tactaataca cgaacttttc
    24061 ttgtattctc agctgtcact tttaaaacct tttcccatct aacaagatcc tttaaaaggt
    24121 aaaaactcac ataaataaag agcatatgac tacttagagt gaataataat tgaaccattt
    24181 gactattata ccatcttctc tgtttgtgcg ctagtttgga aacttcactc aaaaattagg
    24241 gattgttttt caagtaatca atcgcatctt gtagggtttt aacgggcacg attttcatat
    24301 ccgtcttgat tgttttagcc gcttctaggg ctgtttggta gttgtttttc gcgtccggat
    24361 gcgccttttg ttcttcttcg ctaacagggt tatcaggagc aaagaaaata gcagcacctg
    24421 ccctagccga agctacaacc ttcttatcaa tacctccaat gtctcccaca ttaccatcgc
    24481 ggtcaatggt acctgtaccg gcaacaatac gaccattacg aagatctggg tgagctattt
    24541 gagtatagat agctagacta aacatgagac cagcacttgg gccgccaata ccagctgttg
    24601 aaaagctaat tgggacattg ctgattacct ctgtacgatc aatcaagccg attccaatcc
    24661 cattttttcc attttccaag gtgataatct tcccttctgc agacttggtt tgcccatcct
    24721 cttcataggt gaccttgacg gaatccccta atttttgaga actgacgtaa tcaatcaagt
    24781 ctttggaact atcaaaggtc tgatcattga ctgctgtgac tgtatcagag atattgagaa
    24841 tccctttaaa ggttgaatta tccgtcacat tcaaaacata aactccaaag tacttgagtt
    24901 cgatatcctt accagctgtt tttagtcctt gatacttggc catattttgc gatgtttgca
    24961 tgtagaattg attgattcgc ataaattcaa catcggaaga accacctgta gtctcctgag
    25021 cactacgaat atctgtaaaa ggtgtcaacc aagcataaat catatgagct aaagtagcat
    25081 gttgaacacc aaccgtaacg aattgatagg caccagcttc cttatcttct gtgtcattta
    25141 ctttaaggac ttggcgaata tcttccgaac cacctggaac ctctatataa taaggcaagg
    25201 gcactacaaa tgccaagaaa gtcacaatca aggccgcaat gacgtataag ggccatctaa
    25261 tctttttttt catttcttat ttcctccaaa atactctcgg gaacatagca ggcaatatcc
    25321 tgaccaaact tcaaaagctc tctaacgcct gatgaactga tatagagatg ttcaggtcga
    25381 ctatgtaaat aaatagtctc tatatcagaa gacagctgat gattgtagta atcaaaactg
    25441 gcttcatatt gcaaatccga cgcattcctc aaaccacgca ctagacaagt agcacccaat
    25501 ctttttgcaa catcgaccac caattcatca tgagaagcca cgacttcaac attttccaaa
    25561 tgtcccaaag ccttttctag cccccgttta cgattttcaa gagggagaaa tccttgtttg
    25621 tggggattaa aaaaaatacc cacacaaagc ttatcaaaaa gtctgctcgc ccgttcaatg
    25681 atatccagat gcccatttgt catcggatca aatgagcctg tgaataagcc aatcttatct
    25741 gacatagact gtcaccttac taattccata aatcttttcc ttccagatac ccagacaggc
    25801 aatttcttct ggaagttcaa cggtcttatc cgtctcgcac acaaccataa catcttcaga
    25861 aaaaagctct ctctcagcca ttttttcaat atctgctacg atttgttcct tggcataggg
    25921 agggtctaag aaaacgaggt caaattcccc agatacctgt tccaatgccc tttctgcatc
    25981 cattttgagg agttgaaatt ttccaacttc cttggtcatc tggatatttt cagccacgat
    26041 ggtctgagcc ttacggtctc gctccaccaa aacagcactg gacatgccac gcgatactgc
    26101 ttcgatagat aaaccaccac tacctgcata aaggtccaag actcgtccca cttcaaagta
    26161 gggaccaatc atgttaaaaa tggctcccct aaccttatcc gaagtaggtc ttgttgtctt
    26221 gccttctagt gtcttgaggg gacgtccccc atagattcct gatacgattt tcatactgtt
    26281 tattatacca aattatagac aaaaagagaa agaaaaccga accttgcggt tcgattctct
    26341 acaaaatatt ttcgtaagta tcgcggactt cttgaggcca aacacttgtt tgcacttctc
    26401 cgatgtgtct cttgcgaagt aggaacatgg ccatacgaga ttgtccaatt cctccaccga
    26461 ttgtcaatgg gaataggcca ttcaacaaag acttgtgcca ttccaattct aagcggtctt
    26521 catcacctgt aatttccacc tgacgtctaa gagtttcttc atctacacga attcccatag
    26581 aagacaactc aaaggctcca cctaaagact cattccagac aagaatatca ccatttagac
    26641 ccttgtagcc attctcagac tcgcttgtcc agtcatcata gtctggtgca cgtccatcgt
    26701 gcggtttacc atctggcaac tcgccaccga taccaatcaa aaagacggct ccaaattctt
    26761 tacaaatcgc attttcacgt tctttaggtg tcaagtctgg gtagcgttct accaattctt
    26821 ctgtatggat aaaggtgatt tgttttggca agatagactc gatgtcatag cgggcttcaa
    26881 cagctagctc agtcaggcga atagccttat aaatcttctc aactgtttct tttagataaa
    26941 cgatgttacg cttaccattt gggataacct tctcccagtc ccactggtca acataaacag
    27001 agtgggttgc atccaaggaa tcctcatctg gacgaagggc tttcatgtgg acaaagagac
    27061 cctctccttc accaaagcca aaacgagcca aggtgtggcg tttccattta gcaagtgagt
    27121 gcaccacttc ataagtagca tcagggattt ggagaacctt gaccgatact ggattttcca
    27181 caccagacag gttgtcctgc attccgtcac cgaccttact caagatagga ccttgaactt
    27241 cgacaacttc tagcttatct ttcaaatact gggtaaaagt gtttttgaca aaggaaattt
    27301 cttcttgttg atggataaaa cttttcttca tagacaactc ctcaaaaatt taataaacgt
    27361 attatacacc tatttccaag aaaagaaaag agaaaatttt aaaaaaatca gtgtcactca
    27421 aaacactgat ttcatagacc ttttagtcat tgcgaccaaa gatacgtaga atacttagga
    27481 aaagattgat aaaatcaaga tagatgctga gagccattga caccacccag cctgtcgcta
    27541 cacgaccttg tgattgttca taggcgaggc gaatcttttg gttatcccaa gcaatcaacc
    27601 ctgaaaaaac caaaaccatg gctacgctaa tcatataatc aaagaagcca ctagccaaga
    27661 aaatattgac taccatagca atcagtaaac caatgagagc tgccatcatt gctcgaccaa
    27721 tcccactcaa gtctttcttg gtaaaaatac caactgccgc catgacaaag aagagaaggg
    27781 cgctcgatac aaaggcagat aaaactgtac ccggagtata gaaagccacc acaaaactaa
    27841 gggtaaagcc gtttaaaacg gagtaaagta aaaatactgg aagagcagct ggactatttc
    27901 ttgaagccat gctactggca acgaaaacca aagccaactc cgcaaaagta gcaatggtca
    27961 accagagacg cccctgcatc aacaagtaaa ccaactgaga ctgaaagacc gtcaacataa
    28021 ggcctgatac caaagcagat agtccgattc ccagaccaac aaaggcataa accttagcgt
    28081 aaaattgatt gagacctgca cggtcatgta taatagtgtg attcatcctt ttctcctttt
    28141 ctgtgaacat ctttccttga ttataacaaa aaaagttaaa attagcttaa atggaagatt
    28201 aaaataccgg ctgcaactgc aacattcaaa ctctcggcct gccccttcat gctaatatgg
    28261 accaactggt ctgcactttc agccataagg ggactaattc cttgaccctc atttcccata
    28321 actagtacaa aattttctat agaaggcagt tctctgtaat caacagaatc tttagatagg
    28381 gttgttgcta gcactgggat agctaccttt ttagtttcgt caagaagcgc ttgactagtc
    28441 atccggtaaa tgggcagatg gaaatgacta ccttgcatgg aacgtagggt tttgagactg
    28501 tagatgtctg ccgacttatc tgaaacaatc actcctgtaa aacctgctgc atccgcagtt
    28561 cgaatgatag ttcctacatt accaggatct tgcacatctt ccaaaaacaa gaacttgccc
    28621 tgactcaaat cagcttgtcc tacttcttct ttttgaacca cggcaacaat tccctgtgga
    28681 gtctgagaat ccgccaaatc tagcaaaata tcctctgaaa tccagacagt ttgcggaaaa
    28741 gcagctaact gatttcgata attttctagg gcaaagattt tctcaatcgt cactccagct
    28801 tggacagctt cttcaaacaa gtgccagcct tcaatcaaat aggcagactt gcggtatttt
    28861 ttttggtgta atttcttggc attttttacc acagaattgg cttttgaggt tataatagtc
    28921 atagaaatat tataacacaa tcaaaggggt ttggtatgca aaaggttaga atgattgccc
    28981 aaggtagggt gcagggagtc ggctttcgtt ggggtgttta tagcctggcc cttgaaatcg
    29041 gtggcatcac aggtcgggta tggaataacg acgatggcac agtggaaatc ttagcccaag
    29101 cagactcatc tgctatcatg gcaaaattta tccaagaaat ccgaaaagga ccgacacctt
    29161 tttcaaaagt aagctactta gatgtcaaac taagcaactt tcctccctac tctgacttta
    29221 aaatcgcaaa ttaggtctcc agaactattg tatattttgt aaaaaaacag tagaatagaa
    29281 aggtataatt tttaaagaag gaataaaaac agtgaaatct attaaacgtt ttgcattctc
    29341 ggctatggga gtggctatgt tgcttgtctt gactggctgt gtcaatgtcg ataaaaccac
    29401 aggtcagcca acaggattta tttggaatac gatcggagcg cctatggctg aagccatcaa
    29461 gtacttcgct actgataaag gtctaggctt tggtgtcgct atcattatcg taaccattat
    29521 cgtacgcttg attatcttac cacttggtat ctaccaatca tggaaggcaa cgcttcactc
    29581 tgaaaagatg aacgctctca agcatgtcct tgagccacac caaacacgtc tcaaagaagc
    29641 aactactcaa gaagaaaaac tcgaagccca acaagccctc tttgccgctc aaaaagagca
    29701 cggcatcagc atgtttggtg gtgtaggatg tttccctatc ctccttcaaa tgcctttctt
    29761 ctctgctatc tactttgctg cccaacatac tgaaggggtt gctcaagcaa gctacctagg
    29821 cattcctcta ggttctccaa gtatgatttt ggttgcctgt gctggtgtcc tttactatct
    29881 tcaatcgctc ctttcacttc acggagtaga agatgaaatg caaagagaac aaatcaagaa
    29941 aatgatttac atgagcccac tcatgatcgt cgtcttctcc ctcttctcac cagctagtgt
    30001 cacactttac tgggttgtcg gtggtttcat gatgattctc caacagttta tcgtcaacta
    30061 tatcgttcgt ccaaaacttc gcaaaaaagt ccgtgaagaa ctagccaaga acccaccaaa
    30121 agcaagtgct ttctctaaac caagtggacg aaaagacgtt acccctgaac aaccaactgc
    30181 tatcacaagc aagaaaaaac acaaaaatcg caacgctgga aaacaacgtt cgagataaga
    30241 agaaaaaggc ttagctgatt tgctaagtct ttttgcaaat caaaagcccg atgtttccat
    30301 caggcttctt ttctatccat gtacacgttt catataatct tgataacttt cggtatccat
    30361 gagtttttta gcgttcttga cgcgatctgc tgttggtggt ttgactcctt cgagggaata
    30421 tggaattcca agttcacgcc acttgaactc acccatggtg tgataaggta gaatttcaaa
    30481 cttatcaaca tttttgaggg tcttgacgaa cttaccaagt tcaatcaagt catcatctct
    30541 gtctgtcaat cctggaacta gcacgtggcg aatccagaca ggttttccaa tatctgatag
    30601 atactgggca caagccaaga tatttttatt agtttggcta gtgacaatct tgtgctgttc
    30661 ttcgttgatt tccttgatat ccaaaagaac caagtcagtg acagccatga gtttgtcaaa
    30721 cttctcaagg taacgtggtt tattacggaa aggaagagca caggtatcca aggtacagtg
    30781 gattccttgt tccttagcct tggtgaagag agcaatcagg aaatcaatct gcaagagagc
    30841 ttctcctcca ctgactgtaa tcccaccctt atttccccag aaaccacggt agcgcaaggc
    30901 ctctgtcaag acatcatcta ccgtccgttc acgtgactta ttggactcca tagcccaagt
    30961 gtctgggttg tggcaatact ggcaacgcat gtgacagccc tgcaaaaaga caataaagcg
    31021 aataccaggc ccatctactg acccaaagct ttctgtcgaa tgcaccattc ctgtcacttg
    31081 tccataatca attgtttctt cagacatatc gttaccttcc ttgaaaacgt tttatagttt
    31141 tattatatca cgacttgaag gaaaaacaag atttttgcct attttttaga aagcaatctg
    31201 tttttcaatt tcattttcaa tctattatca gattattctt caaaatcgaa gccatataag
    31261 gttgcaaaat agtcctcagg gcgctctgca cggcggattt gacgggcttt accttcttcg
    31321 gtatagagga tttccgcaga acgtaatttg gcattatact ggtagcccat tgaaaatccg
    31381 tgggcacctg tatcatgaat taccagcaaa tcaccgattt ctgtatgagg cagttcgcga
    31441 ttgactgcaa atttatcatt gttttcacag agtgaaccaa ccacatctac cgcttcagct
    31501 ggtccatctg gatgggtcac gttgctaata tgatggtaag ctccgtacat agctggacgc
    31561 atgaggttga ctgctgaggc atccacacct agataggtac ggtaggtttc cttcttatga
    31621 gtcactcttg tgactagagc accgtgaggt gccagcataa aacgacccaa ttcggtgaaa
    31681 atcttgacct gaccaagacc tgctgacgta agaacttctt catacacctt acgaactccc
    31741 tcaccaatca aggcgatatc gttcggctcc tggtctggac gataattaac accaataccg
    31801 ccagaaagat tgataaagtc tagcgaaatg cccaactttt ccttgatttc aacagccagt
    31861 tcaaagagct gacgagccaa ctctggataa tagagatggg tcacggtatt ggacgctagg
    31921 aaggagtgaa tcccaaaagt cttggctcct ttttccttca agatagcaaa ggcttcaaag
    31981 agctggtcct tggtcatgcc aaacttagcc tccccaggat tgtccataat gtctgtcccc
    32041 agttcaaaaa cgcctccagg attataacga caagagatga tttctggaat gcctgctact
    32101 ctctccagat gttcaatatc ttcaaaggca tccaagttaa tggtcgcacc caattcacgt
    32161 gcataggcgt attccttgtc tggcgtgttg ttggaagaga acataatctc agaacccaga
    32221 aagtccagtt tatggctcat caaaagctct acataactag agcagtccac accacaacct
    32281 tcttcttgga gaattttcaa aatagctgga gttggagtag ccttaactgc aaaatattcc
    32341 ttaaagccct tgttccacga aaaagcttgg ttgacggctc ttgccttctc acgaatcccc
    32401 ttctcatcat acaagtgaaa gggagtcggg aactcggcaa caatcgcttc taactcttct
    32461 ctattgataa atggtgtttt cataagcttc cttctattct gtttgcaaag aaaggctggg
    32521 acaatcgttc caacctttag ttctatctct tatttatctt cgtcaaagat attgccaacc
    32581 tcaacatcga tggcttggtt cttgacatca atattggtta ccttcaagag tgacttgtag
    32641 tcaaactgct tttcacgttc ttcttgggca ttgtccgcaa agaccgctac acctgccagt
    32701 tctgagtcga actcgtgcaa gagactaatc ataccattga ccgttccgcc acctttcaag
    32761 aagtcatcca caatcaagac acggctgcct gccttaagac tacgttttga aaggaacatt
    32821 ttctcgatac ggtcaccact tgaacctgaa acatagttga cgctaacagt tgaaccttcg
    32881 gtaattttca ggtcacggcg cacaatgaca aaagagacat tgaggacatt ggcaactgca
    32941 tttgcaagtg gcacaccctt agttgctacg gtcataaccg cgtcaatttt ttggtccata
    33001 aagcttttgg caataatacg accaatattt ttcaagatgg ctggtgtgct aagcaaatca
    33061 gacagataga tataaccacc tggcaagata cggtcacttt ctgacaactt ggtacgcaag
    33121 tcttcaacca tttccttagc atcctgactc gaaatagacg gtgtgaagat gacacctccg
    33181 ccagccccag tcactgtctg gatatgaccg atttcaattt cctcaaaggc gcgtttgata
    33241 atgacgatat cttctgagat ggatgattta gcagactcat acttttcagc aaaagtattg
    33301 agactagtta gtttataagg attattaatc aaatagttgg aaatgacaac catccgatca
    33361 cttcttctta atttcatttc tatttcctat tccattttta ttcaaaaaat caaaaagcaa
    33421 actagaaagc tggtcgctgg tggttcaaaa cactgttttg agattgtcaa tagaactgac
    33481 aaaccctgta atatacctgc atatatacat acgacaaggc gatactaccc tagtttgaag
    33541 agattttcga agagtattca tttttgtctt ttacttatta taccatattc acataaaaaa
    33601 acgaacattc ttatcctaaa aaatgctcat ttttcttaaa ttatcaatct aaatctggtt
    33661 tatagaagga acgattatcc atagcgaaga ttttattggt catctctcct ttatccacca
    33721 aagccagagc tgttgacatc atcatcatgc ttgcatccag attgtcaatc atatggataa
    33781 tctctgcctc cataatacgt ggacggactg gacttccata ttcaagcaag ccgtggtgac
    33841 tgaggatgac atgacgaagc aaaacgactt cttccttggt atcatcgatg ccgagttcca
    33901 taactgtctt ggtaatttcg ctatcaatga gagcgatatg tccaagaaga ttacctcgca
    33961 ctgtgtactc tgtctggtct ggccccgtca actcgataac cttagctaag tcatgcagca
    34021 taatccccgc atagagcagg ctcttattga gctgaggata aacttcgcta atagcgtctg
    34081 ccaaacgtac catggtcgcc gtatgataag ccaaccccgt ttcaaaggca tggtggttgg
    34141 tcttggcagc tggataggag tagaattcct tatcatactt ggtgtagaga tttcggacaa
    34201 tccgttgcca gacaggattt tcaattttga aaatcatttg cgacatgtag tcacgaattt
    34261 ccttgacatc aactggtgac ttgaccttga aatcggctgg gtcattgggt tcaccagctt
    34321 gaggcaggcg gagagtaatt tgattgactt gaggggtatt gttataaact tctcggcgtc
    34381 ctttcatgtg gacaacctta cctgcggtaa aggcctcaat gttatgaggt tgggcatccc
    34441 agagcttccc atcaatctcg ccactatcat cttggaaggt aaaggctagg tagtttttcc
    34501 cagctcgagt ttgcctcagg tcagctgatt tgattaggta aaagccttca aatagctcat
    34561 cttttttcat gtgactaatc ttcatattct tcctcatttt cttgaaaatg gagtagatca
    34621 agcgcaggct caccttctga caactcaatg tgacggagcg tccgctcgat agctatggta
    34681 cgacggttta ataattcatc aatattgcca gaggcatgtt ggagatgttt ttgtgccttg
    34741 accagaatac caccaaactt gccaaactcg gtcttgacac tggcaagagt cttgctgata
    34801 tggtcggcac tcttttggat attaagggtc ttgaaaccaa ctgatagaga gttaagaagg
    34861 gctgataggg tacttggtcc tgcaacaata atctgttctt cccgtctcaa atcatcaaag
    34921 aagaccggat tgcgcacaat ctctgaataa agaccttctg tcggaacaaa caagattcca
    34981 aagttggttg tccgaggtgg tgctatgtac ttgttcctaa tatccctagc aaagcgcttg
    35041 acgcttgcta ggagtgactt acgacagcgt tcaatctcat ccttgtcacc tgtctcatag
    35101 gcttcttcca agcggtaata atctgccagt ggaaacttag agtcaattgg cagatagacg
    35161 tattcttggt cgccttgtcc gggtaacttg atggcatact ccactcgttc actagagttt
    35221 tcaaccgttg cgtattctcg ttcgtactgg gcaggtgtca tgatgtcttc aataatttgc
    35281 cccagttgca attctcccag aatccctcgc gtcttggttc cagagagaac cttgttaaga
    35341 gctccgacat cacgggcaac tgtctgcatt tctccaaggc cacgattgac agactccagt
    35401 tgtttagaaa ctgtctcaaa ggaagcctgt aagcgtgtct gcaaggtctt ttctagtttt
    35461 tcctcgaccg tctggcgcat ttgttccaaa cgttgctcat ttgattcctg caaggcttgg
    35521 agacgttggt ctgtcttgtc tctagtttgg aggagattat ctgtcatttc ttgacggact
    35581 tgggtcagac cttggtgcaa ttcaatccgc acttcttgca aacggtcgct gacaaccact
    35641 tccaaatctt tttggtctaa ctggctggct tgtctggctt ggtcaaagcg gtaatccaac
    35701 tggtctgaca aatgatctgc ctgatcctcc aagctcttac ttaagtgttt ctcctgccta
    35761 tcctgccttt gccaaatcag aaagagacca gctagattgg caattaataa tagaataagt
    35821 aaactttcca tcctacctcc tgtccttgct atgcagtacg accacataac catctgggca
    35881 agttaccgac acttccctat ctatatattc gttagaagcg tacacttttt taaagaaaaa
    35941 attttcctct gtcaactcat acttggctcc aagaatagtc agctggctat cccgaactgg
    36001 cataaaggct agatagtcgt agtctgaacg aggttctagc tgactgattc cttctggaca
    36061 ataagtaatc aagttttgcc catcctcaat ttctatttga tgcatatagg atgccaactt
    36121 aggattgcta ggcagaaaga cattggccaa catatggtca atacggccac ccaaggcacc
    36181 gaaaatagta acctgagcct gaggattttg cttaaagatg gtcaagagag ccaattccaa
    36241 atcagtatca tctttttctg gccgggcttg gacaaaatac tgggcacgtt tttgaatcac
    36301 ctgtcgctct tcttccgtca cagaatcaaa atctccgact gctagagcaa gaggcaaatc
    36361 ttcttccaag atccagagcg agcctcgatc cacaccaaca aaaccatcaa agtccgtccg
    36421 ataatgaccg cggtctccgc ctgcaaaaac ggcaacccta gtccagttgt tttctgagag
    36481 tttgtactcg ctcattgaca tctcccttaa agacatagga acctgctaca aaaacggtcg
    36541 caccagcttc tttggcttga gcaatagttt ggtcatcaat cccaccatcc acttcaatct
    36601 caaagttcaa acctttttca tcacgaaggg caaccagctc acgaacctta tccatggttt
    36661 ctggcagaaa ggcttgacca ccaaatccag ggttaactgt catgactagg acttggtcaa
    36721 ctagatgaag cacatgctta atcgcttcaa ctggtgtacc aggattgata acaactgatg
    36781 gcttgacacc gagtgaacga atcttttgga gggcaccatg aatatgaggc gttgcttcca
    36841 catggatact aataatatcc gcacctgcac gcacaaagtc ctctaaatga tgctcagggt
    36901 ttgacaccat caagtggcag tcgaaaacca tcttactatg aggacgaaga gcttcgacca
    36961 cacccgcacc aaaactgatt tgcggcacaa aatgaccatc cataatatcg atatgggcat
    37021 actctgcccc agttgcttct aggcgtttaa tttcacgttc aaagttggca taatctgctg
    37081 ccagaattga cggagcaatc ttgtattgag acataggttt ctccttattt tggaattttt
    37141 ttgctgactt ttttataggt ttctctgcga ttttcaattt cgctgaggaa ttgcaggtag
    37201 ttgtcaaaac ggaagggcgc aatggtacct tcttcaactg ctggcttgac agcacaggac
    37261 ggctcatggg tatgggtaca agtacggaat ttgcagtctc gactgacagt ggcaatctct
    37321 ggaaaggcct gattgaggtc ttcagccgtt gatacttcat aatccagtga tgaaaagcct
    37381 ggtgtgtctg cgattttacc cccattgagg ttgtaaaaac taacagctcg agtggtatga
    37441 cgcccgcgac ccagactgtc tgaaatttct cccgtttcaa gattaagatc tggtgcgatt
    37501 ttattgagaa gagttgattt cccaacaccc gtctgcccca taaagaccgt aaccttgcct
    37561 gttaacaaag gcaggagttc ctctttactg gtcacaaagt catatccgat gtcaccatag
    37621 gtctgctggt aaaaatccag ttctcccccg tcttccaaca aatccatttt agaaatatag
    37681 acgatgggat gaataccctt atgctccaaa agaaccaaga aacgatccag caaattgctg
    37741 ttaaaatcag gttccttgac agacatgatt actacagctt ggtcgatatt gacaataggc
    37801 ggacggacca gactgttttt ccgttcgtga atcttgagaa tatagccttc tgaattttcc
    37861 tcggcagaga aatctaccca gtccccaacg taaggggtat gccctttttt acggaaattc
    37921 ccacgcgcgc gtgtttgata gacttggcca tcactctcta catagtagaa cccagccaag
    37981 gctttaatga tttgtccctg caaaataact cctttaaaat tgttagttcc attataacaa
    38041 aaaaaagcta ttttagctta gcttctcttt acaatttcga taagtctatt ctaaaagaaa
    38101 aagatacact cacgctttag ataccaagtt ttatacaaaa ataacgaatc tacctcctta
    38161 tataaaaaca ggcgaacaga gagcctaaaa ctccctgttc gctttacttt ttctgtgtgt
    38221 aatagaaaaa acctaataaa gcaagacaaa aaatatgaat ataaactcca tacatcatgt
    38281 ggggaaagac agactctata aaatagcctg gtagatagat gattggaaat tgatagaaat
    38341 cataggtcgt tagagatagt aaacaaagaa catacataaa tactgctaca attagaaccc
    38401 atccttgctt tcgccataga aaaatcatca ataagaacag acaaagtaga tagattgacc
    38461 aatttcgcaa cataaattga aaaccataaa tcatactttc agtcgtttct ccatcaatca
    38521 catcaactac tttatagaaa ggtaaacaat agctcactaa aaaaagaagg ggactaatta
    38581 tttttttcat attctctacc atggattatt ttgcaagtaa gctgaccatc tatctccata
    38641 tcgaatcaaa ttaacagtat aattagttac tacccgattt tcacctggtc caaccttaga
    38701 aaaacctgtg ctatactccc aactacttct tgcacctgga tgaaaccatt tttgctggga
    38761 tgaataccaa ccaccttgtc taacttccac acttgaagat tctatttcga tatccctttc
    38821 atggaagtca actcctccac ttattttagt aatatttttt tgtacacctc catcataact
    38881 cacccagtga acaacagtat acaattccac actataagta ctatcaaact gactttgatg
    38941 agtagtaatg ttttgagtat aagcgtgcac tttctgtata ccaaaaatat ggtctaatat
    39001 attcgttggt ttagcaagct tattgtaacc ctcttcaaca aaagtagcct tctctaaatc
    39061 agcggtataa acagtttttc cttgtactac ttgattgttt atagaagtaa tacggctatc
    39121 cacaacaatg ggggccacca tatctccatc gctagtttct attttagctg cctctttcac
    39181 ctcatataca actcgatttt cttcagactg aatcacttct accccatttt tttcaggtat
    39241 agataatcta gtttgcccat tagaaaccgt tatatttgga ccaatattct tctcatttgc
    39301 ataagtcgca ataggaaatc ctgatagaac cactgcacac ataaggctat tgactaattt
    39361 ttttctcatg aatatatcct tcccattttc aagaggagta aaaatagcta atataagatg
    39421 aacgtttcct tatatttcag aataggatat ctatctgaaa gcaattcaca ctcctataga
    39481 taactgttcc aaatcttggc tacatatatt tcaatagttt gctacaaaaa actcctttct
    39541 aagtctattg aacatgccct tattcaccta ctaatatatc acaaaaataa ataaatacaa
    39601 gactgttttt tctactagtt ttatgataga atagtattgt tagggtaaat ttcatatata
    39661 aatgtcgagt gaaaaatcga tggagcagaa atcggtagac aaagactcga tttcgttggt
    39721 ccagccccac aaggctaatc aggtatttca cgagtttaaa aatctaatga agtgcccaat
    39781 caactactga ttcattgatt taatacgaac tatagtggat tgaacctaga aatagtacac
    39841 taaggattct aaaacgtttc tagaaattaa tttgactttc ctaatctctt tgttcatatc
    39901 ttatttcaat ctactatata taccaaaatg ctaggacaaa agtctttaaa atcagagaaa
    39961 cgcatattat caggtgttgg aaaaccttga taatatgcgt tttatcatag aaagatctac
    40021 ttcatttttt actaaaatta agtttttgtc cctgcatctt agagtccttg ccctttaagt
    40081 gcatctgcta ggctggcaaa ctcttccaag ctgagagctt ccccacgcac acttggtgac
    40141 aagcctgctt ggtccaaagc cttggtcagc ttgtccttga cctcttcagt cttgccaaag
    40201 taacctgtca agttattcca caaggtcttg cggcgatggg taaaactagc cttggaaacc
    40261 ttaaagaaaa agttctcgtc ttccactgct acagctggca ctggacggcg caccattttc
    40321 aagatggctg agtctacatt tggtgctggc acaaagactg tacgcggcac gataaaggca
    40381 accttggctg tcatgtaata ctgcacagcg atagacaagc taccgtaagc cttggtattt
    40441 ggttgagccg agatacggtc cgccacttct ttttgcatca tgaccacaaa ctcactaaaa
    40501 ggaatgccac tctcgattaa gtgcatgaga ataggcgttg tgatgtagta aggcaaatta
    40561 gccactacct tgattggcag gtcaggattt ttgaaattct ggatatgttg cgccaaatcg
    40621 accttgagaa tgtcctcgtt gactacagtc acattgtcaa aatcacgcaa ggtatctgcc
    40681 aaaatcggta ccaaacgatg gtcgatctca aaggccataa cttctgctgc acgctcagcc
    40741 aaaaactcgg tcaaggcacc aatacctggc ccgatttcaa tgacattgac ctggtcatca
    40801 atctcagccg tatccacgat tttttgtagg atattggtat ccgtcaagaa attttgccca
    40861 aaggactttt taaaggtaaa accgtgacgc tccagcactg ccttggtcac gctataatct
    40921 gcaattctca tctattctct tttctattat ctgttactac tattgtaaca cattcccctt
    40981 gtattttggg ggtgaaaatc ataccaaaaa actatctttc ctcatgaaga aagatagtct
    41041 tggaaatctt taaaagtggc cttagcgctt ctctcgaaac atacgttcat actcttcgaa
    41101 aatctcttca aaccacgtca gcttcacctt gccgtactca agtacagcct gcggctagct
    41161 tcctagtttg ctctttgatt ttcattgagt atcaaaaaaa tcagcttctt gataacttcg
    41221 attttcgggt agggtcaaat ccacatcctc ctccacatca tccactgtca gttcaaccgt
    41281 ttgaggtaaa tttttcaaac gataatgctt ttgcctttgc ccttcactac tagcaaaatc
    41341 aagcaaatag ccatgcactc ggatttgaac caaaaggaga ggattggtca tattttccat
    41401 gatgaggata tcttataaac cacctctggc actaggataa tcagataccc tgcgaatacg
    41461 gattttttca cacatgagca agtttcctca tatcaatgat ttcatcagcc ttattccaga
    41521 ctaggggatt atgggtcgca atgatgataa ttcgattttc atctttcaaa tccaccaaga
    41581 gattcataac ctcctctgaa ttttcaggat caagagctgc tgttggttca tctgccaaaa
    41641 tcaagggtgg atttttcaaa atagttttcg caagggcaac tcgttgggcc tctcccccag
    41701 ataaagtata aattttttgt tctaaatcca aataccctag attaactttt tctaaagccc
    41761 ccacttgcct ttccaaacgt tctacttttg agattttctg accaacaaaa cccaaatcca
    41821 aattttcttt gattgattgg ttttctaaga ggccaaaatt ttgaaagaga tagcccatct
    41881 gatctcgaaa atactcacga gtgggaatgg tttttaaatc tttcccctga tagagaaccc
    41941 ttcctccatc tatcttttct agctttccca agatattcag cagcgtcgtc tttccgcttc
    42001 cactctttcc gattaaggca taaaccttgc ccttctccag cttgagattc aaaccagaga
    42061 aaatcgcgcg gtcattaaat ttcttttcca atccttgaat atcaatcatc ttattttcct
    42121 ttcaatactg ccatgctacc agcttcttct tttttgtcct gccttactaa aatcaagagg
    42181 gcgttaagcg taaacaaagc tacaactaga gcgctaatca aaccatctct tgtcaaaata
    42241 ctagatagga ctaggccaag caagagaact cctccttgcg ccagtaaata cttgccatga
    42301 agctcataga ttgtcatacc agcaagacgt ttaatcataa gctcccgtct gaactgctca
    42361 aaatagagaa gattcatgga atcaaataac aagatagccg tagacagggt caaaatcgtc
    42421 ccaataagga gagagtaaaa ctctacccgt ttgtcattta gtaccttggc aaaaaatagc
    42481 tggcttttta ccaagtaaga aaccttgtga tacagacctt gctcttttag agctgtgatg
    42541 ctgtctccat atcgatctag tttcaaggca ctattagccg tagttcccca caacatccct
    42601 gcaacaggtc ttgttccagt cgcttgcggc gttagaacta caataatcgg atcttttagg
    42661 tactggcgtg ttgtcttgta cccatcatta tagaggaaac gttcctgtcc tgtttctgta
    42721 aaagctagac ttacctgtgg gaggtagtat ttctgactcg tcacttctac actttcagat
    42781 gaaaagtttt gcaggtaatc tgtaaacaat ctttggtagt aggtagactg ctctcgcaag
    42841 ctctcaggca agattagccc aaactctccc tcagacaagt tttgcatctt gtccataaac
    42901 tctgaagaaa cggtaatctt ttcttctatc agatagcgtg gtgagacata gataacattc
    42961 cctgacggtg tgtagtcact gagacgattg ccatctaggt ccacttctgc tccgtctgag
    43021 aaattgtcaa cattgctcat aatataaaaa gagtctgtat tggctaaccg ttcttcagta
    43081 aatgtctgcc actcacgatt atccttacgc gttccttctt catcggcaaa tgcactagac
    43141 caaccaaagg atagacggta acggtctgag gactggctcc atttattgct agctctctcc
    43201 atttcctgca tttcacggta gtggggtagg agagctgtcg cactcgatcc gaccaccaat
    43261 acagctaaga gttgccccac catcatcaat gtcatcatac gtttgagagg gagtttccct
    43321 ttcaatagat ccaccagact attttcctgt aaaccaagta gatagacgac acttagtaag
    43381 gtagaaatcc ctgccagggt caatccataa agtagaagag caatgatgac cagttgcacc
    43441 gttgccataa acaaggcacc ttgataccag agaatcccca atcccaaaag actggatacc
    43501 agcactgagc agataaactg tctcacatct tctaacactg gtctgagagc aactccaaac
    43561 aagctctcac cagctattaa gcgaatccct gcctgacgaa gggatttgat ccgataaatc
    43621 agggtcagac tcataaaggt cagcagaaaa atagctaaac tcagtagcac cataggggtg
    43681 gccgccaata gtaagactat cgaaaatgga tcttctccat tcgaaacaaa gccttgatag
    43741 ccaagttctt tcaaggtggt ctgtaagctc actccatcca aacttcctga cacaatcaag
    43801 taagacccta ataaatcact cgtttctgca ctctccttgg aggaaatggt cagaccttct
    43861 ggaagctctc cctcaccata agtggcatag gtaaagagtg tttctccagc ttcatttggc
    43921 tcaacgattc gacgggcgat gagactatta tgctctaccg ccaagtgact caaaacctct
    43981 gtcacctctt cgcgactagc tactggttga tttatcatca ttcctgtcac atcaacagaa
    44041 ggatagttac caaataaaat ctcttctcga tggtcaacgg aagttatcac catataaagc
    44101 gataccaata ccattgaaat caaaataaat aaacgtttca tcatttcctc caaaaagtta
    44161 cttggtcact tagtgagaag gtgaccacag tcactgcgat gttaagaagc ttattaagtt
    44221 ctttctacta gcaacatctt caaatacatt atatccgttt tttcaagaac tatcaaggac
    44281 atcaatgtcc ttaaaatcta actatttcat attattttta gcttatatct aaaaaaacag
    44341 ttctaaagac gaactttaga actgttttga tacgaggaca aggacatttt tgtcactgat
    44401 tcactatgtt tataaatatt ttttgacatc ctcttgccat tcctctgtca atttctttac
    44461 tagaaatcca tctccaatta gcttcgcaaa tgttttagaa gactgataaa atgattcagc
    44521 taaactaaaa tctctttctt ctcttaatgc ttgcttccac aaaaacataa atacaagagg
    44581 tttcttttga taatcttgag ttttatccat aatttcttgt aaacacgata gataatcatt
    44641 aaaacaatca gttactccta ccttttcaag acaacacatt cctgaaataa gagtatctct
    44701 aattataaag aagttttcta atttagttac ctttttctgt tccaaaagaa agagcattag
    44761 cttttcgatt tgatttataa atttggcaag atcttttcta atgagcattt gataaaaaaa
    44821 caaacgaatc aacaacatat catttgttga ataaacttct ttttctatga tctgagacat
    44881 atgttcctca agtattaact ctgcatattc aggccttcta gttctagaag tatccaaaca
    44941 cgcctgcaat acttcacatg ctaattgttc ttctttagga agattatcaa agtatgtttt
    45001 ataaatctct tccaaacacg cttccttctt atcgtactcc tcttctttac catagattgg
    45061 ttcacgtaaa atctggtatt tcaattctaa ataagcagga ggaagagctg aaaaatccgg
    45121 cataaggcta taaactggaa ctcctagccg gcgagcaata taggctaact tgggcaaact
    45181 cggttgcgaa gctccacttt caattcgcga cagttgacga actgtcagtt cttgctcatc
    45241 tccacaaaaa tatggacgac taactccttt ttctatccga atctctttaa ttttttgacc
    45301 aattaacatc agacgcctcc tcttctacct gcttcgaaaa atactgtgaa acttaaaaaa
    45361 ttgtaacggc tacatctttc ctactcataa gatttcatag cttcttccac ttctgccaaa
    45421 gtaaccccaa acaactctag gcgtttgagg agttgcttgc cgttagaata gccgattcgg
    45481 agagtctctc cgagatattc tctacgctta cggctgtctg cccctgctag aaaaccaagg
    45541 cgaatcaagt cgctacgact aatgtcaaac tgactctcat gttcaaattg ttctgtcacc
    45601 tgagctagag ccgttttcag gtcttcatag ctggcatgct caattcccag agaacgcccc
    45661 ttggtcttgg actttggaac agcttcatct cgcttgagaa aggcatgccg aactgttgga
    45721 atggccgtca taatcatgcg ccgaatccgc tccccattaa aatctgggtc tgtaaagaca
    45781 atgactccat gacgttggtg caggcgctga atccgctcta tatcctgagc attgatggca
    45841 gaacctcgag tctcataggt ctccacatcg aaataacgtt tgagattgac cgtatcatca
    45901 cgcccttcaa ccacgataac ttgagaaatt ttctctttca ttacttgctg tccaatccaa
    45961 aaatgcgttc tgcatttgca gtcgttgcta ccgccagctc ttctgtcgtc ataccacgca
    46021 agtcagcgat aaagtcgacc acatagcgag tataggctgt tttattttca cgaccacgct
    46081 tgggtacagg tgctaagtaa ggcgcatctg tttccaccaa aatcttgtcc aaaggtaact
    46141 ctttagctgc ttcttggagg tcagttacct tcttaaaagt caccactcct gagaaggaaa
    46201 tggtcatacc aagatccaca aacttctctg cccactcaag cgtccctgaa aatgaatgca
    46261 tgataccacc acgaggacca acgccctcac tcttgataat ctcataggta tcttccagcg
    46321 catcacgggt atggacaaca aaaggcaaat ccaagtcctt agatagctga atctgacggc
    46381 gaaaaacctg ctcctgcacc tctttgggcg ctgtcatcca atggtaatct aagccaattt
    46441 cacctaaagc cacaaccttg ggatgtttta acttatccaa caagtaagcc tcaacttcct
    46501 ctgtataagt accagcttct gtaggatgcc aaccaatagt cgcatagagc tgatcatact
    46561 catctaccaa ctccaaggca cgctcaatcg tcggtttatc aaaaccaaca atattcatct
    46621 gtgtcacacc catctcagca gccaaggcaa tttcttctgc ctcacgacct gcaaattctt
    46681 ctacattcaa gtgtgtatgt gtatcaaaaa tcatctcttc taacctcgtt ttctatcttc
    46741 tattatacca aaaaagagga ggggcaccta atttttcggt ttcccctcct ctcttcaata
    46801 gagagctatt ctgctatctt ttctatccga tattgcccat ctcctattcc acagttagag
    46861 acagaagaga ttggctacat tgatagaata ttcctattca gctaaagtat gtgattatct
    46921 tgggttctca cttttctcac ccatcactag gattgatgac ttctcaaaat cccccttata
    46981 atctaacttt aagtagagaa tagaattttc tagctgttct attttctacg tctagtcttt
    47041 cttcctagca aagcaaaacc acttgttgcc accactagac caagactagc aagtgctgca
    47101 cttgatgctg aacctgtgtt aggtaattgt ttgccagcag gtgactggta ggtaacatct
    47161 tgcattgttc ctgcagttgc ttgcggtgca cttgttgtct taggagcagc attaggagcc
    47221 actggtctct taggaactgt aaccatgaca atggcttgca ctccaatcgt ttctgcttcc
    47281 ttcacatctt ccatagtttt cgcattttca atctctttga gagctgcttg tttttctgct
    47341 tccactcttg ctaaaagttc tgctttttct ttatcagaaa gcggtgcgcc tttgatttca
    47401 tcctgcttgt ccttggctgc tttttcaatg gcatttttag ctgattcttt ttcagtagct
    47461 aattgcttag aagcttgtga ttgagctgag ttttgtgaac ctgtgtgagc tgatccaccc
    47521 gcctggctac caccgcctgc attcgcatta gcatctgagc ttccagtatt gcctccctta
    47581 tctccacctg gtgtattttc tagcttatac tctggtgtag cttcttgagt tacagattca
    47641 cctttcgcag attgttgaac tgtatctttt cctagaatcg tcactactga accatctggg
    47701 aatgtgattg ttgctgtacc atctccagct acattgattg tcgctccgtc taatgctgaa
    47761 ccatttgctt gtaaaatagc aaccttaact ttttcttcat ctgttaaatg agttatatct
    47821 tttacatcta ctctttgagc aggtgcttta acagttgatt tttcagcagt cggtttagtg
    47881 ctatcttgtg cttttggatc ttgtgctacc aattgatttc ctggaattgt aatagctgaa
    47941 ccatctttaa agacgattgt cgctgcgcca tctccagcta cttcaacttt atagtaaaat
    48001 gaaataataa caggacaaat cgatcaggac agtcaaatcg atttctaaca atgttttaga
    48061 aatagaggtg tactattcta gtttcaatct actataacat cgcttccgaa tccatttgca
    48121 tctactgaac ttttttacaa aaataaaaat cagtagactc gagttcctac tgatttttga
    48181 tagaattcgt ttggattatg cagccaaaac tttgcgtcct ttacgacgac gagctgccaa
    48241 tacgcgacga ccatttttag ttgacatacg gttacggaat ccgtgtttgc gcgcacgacg
    48301 aagtttactt ggttgataag tacgtttcac gatgaatacc tcctcataga ttttgtattc
    48361 gtttagccgg ctataaagtg atcagttact aaacatactt tactattcta tctgattctt
    48421 tcacttttgt caatagctct aggcaaatgt ttccagcttt ttcgaatgca agcc
//
LOCUS       DAVBIC010000007        47058 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.007, whole genome shotgun sequence.
ACCESSION   DAVBIC010000007 DAVBIC010000000
VERSION     DAVBIC010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 47058)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47058)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47058
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.007"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            51..299
                     /locus_tag="VQ664_000397"
     CDS             51..299
                     /locus_tag="VQ664_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2788627.1"
                     /translation="MVSSSGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPTSQFY
                     QKFVDEMGRIYSGNLILQELITVNGAYKATYIGELSSN"
     gene            430..1602
                     /locus_tag="VQ664_000398"
     CDS             430..1602
                     /locus_tag="VQ664_000398"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HET2788628.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENADSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTALSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            1602..2876
                     /locus_tag="VQ664_000399"
     CDS             1602..2876
                     /locus_tag="VQ664_000399"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HET2788629.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFT
                     AQVHQRQMIGQVALYQVANPKLAQEKIASKKAELLEFANQAYPSIVKRGGGARDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLIGILSNYATDSL
                     VTASCRMAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VAFSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVERLISDKTFNLETAQRYLENLRS"
     gene            complement(2912..3877)
                     /locus_tag="VQ664_000400"
     CDS             complement(2912..3877)
                     /locus_tag="VQ664_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET2788630.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     GYKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQTIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(3858..5312)
                     /locus_tag="VQ664_000401"
     CDS             complement(3858..5312)
                     /locus_tag="VQ664_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HET2788631.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLVHFKETGIKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFKSQYYAVVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLVFVEEHPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDRFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRASEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN"
     gene            5689..7572
                     /locus_tag="VQ664_000402"
     CDS             5689..7572
                     /locus_tag="VQ664_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HET2788632.1"
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEV
                     IENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQ
                     RAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
                     LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGS
                     VLPAFIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYI
                     LIATKAILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAA
                     MTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAG
                     AIGGGLASILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYE
                     DEVDATAAAKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQG
                     IAVKPSQGVVYALADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFEAKV
                     AQGNKVKAGDVLGTFDSNKIAAAGLDDTTMVIVTNTADYASVAPVATGSVSKGDAVIE
                     VKI"
     gene            7721..8608
                     /locus_tag="VQ664_000403"
     CDS             7721..8608
                     /locus_tag="VQ664_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET2788633.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEMVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGTSLEARTGVRGETIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(8928..9545)
                     /locus_tag="VQ664_000404"
     CDS             complement(8928..9545)
                     /locus_tag="VQ664_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HET2788634.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(9960..10148)
                     /locus_tag="VQ664_000405"
                     /pseudo
     CDS             complement(9960..10148)
                     /locus_tag="VQ664_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(10658..10738)
                     /locus_tag="VQ664_000406"
                     /pseudo
     CDS             complement(10658..10738)
                     /locus_tag="VQ664_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            10854..11747
                     /locus_tag="VQ664_000407"
     CDS             10854..11747
                     /locus_tag="VQ664_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2788635.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQETYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            11744..12682
                     /locus_tag="VQ664_000408"
     CDS             11744..12682
                     /locus_tag="VQ664_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2788636.1"
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHLQGS
                     SMAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLEQTIQFTEKIDEA
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILDHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFF"
     gene            12683..12943
                     /locus_tag="VQ664_000409"
     CDS             12683..12943
                     /locus_tag="VQ664_000409"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2788637.1"
                     /translation="MTALGAAGDNLLLKIGSYIPFISTFFMPFRTINGYAGGAEAWIS
                     LAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTFKRALSYK"
     gene            complement(13296..14063)
                     /locus_tag="VQ664_000410"
     CDS             complement(13296..14063)
                     /locus_tag="VQ664_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2788638.1"
                     /translation="MFWNLVHYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLAISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAAYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVKELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(14080..14775)
                     /locus_tag="VQ664_000411"
     CDS             complement(14080..14775)
                     /locus_tag="VQ664_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2788639.1"
                     /translation="MSLLVFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            complement(14780..15145)
                     /locus_tag="VQ664_000412"
     CDS             complement(14780..15145)
                     /locus_tag="VQ664_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET2788640.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMIH
                     FGYEKEELPGVVSDYIKGV"
     gene            15285..15758
                     /gene="nrdR"
                     /locus_tag="VQ664_000413"
     CDS             15285..15758
                     /gene="nrdR"
                     /locus_tag="VQ664_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HET2788641.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            15759..16928
                     /locus_tag="VQ664_000414"
     CDS             15759..16928
                     /locus_tag="VQ664_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HET2788642.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLALHAPLSSQD
                     FLEHPVYRRLLEKKIGDSAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLEHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFNPKEATIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEEAVLRIRER
                     GQKTKTQKQNQTAPAKTNIPKWSNPDYKNETSEETRLELERKKQELLARLEKGGD"
     gene            16929..17825
                     /gene="dnaI"
                     /locus_tag="VQ664_000415"
     CDS             16929..17825
                     /gene="dnaI"
                     /locus_tag="VQ664_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HET2788643.1"
                     /translation="MESVGDVLKRQPSRFYYQDLVQKIMKDPDVAAFIQQESLTPEEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVKNHGYADVSYEETPELIAAEKEAA
                     IKNRLKLINLPASLKKASLAQVDLDDLGRLPVFEKLLAFVEQYPAIRKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAISDGNVKTLVDEIKLSEVLILD
                     DIGAEQSTAWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKVKHGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            17822..18535
                     /locus_tag="VQ664_000416"
     CDS             17822..18535
                     /locus_tag="VQ664_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HET2788644.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQHHDMKPRLPLENVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQ
                     FGQAEPSSTRKNLEQKKLL"
     gene            18549..19859
                     /gene="der"
                     /locus_tag="VQ664_000417"
     CDS             18549..19859
                     /gene="der"
                     /locus_tag="VQ664_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HET2788645.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            19950..20285
                     /locus_tag="VQ664_000418"
     CDS             19950..20285
                     /locus_tag="VQ664_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2788646.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            20425..20760
                     /locus_tag="VQ664_000419"
     CDS             20425..20760
                     /locus_tag="VQ664_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2788647.1"
                     /translation="MEYLFKMIILLPCFYFFSWIEKANRDSKIFPIFYYFYWIYITLY
                     ALFSLAWTVFSVLFFNIVLRNLTDIKLWGIWLLLLLIAFASDWLDYICFKKMLDLRRE
                     LGKSKGGRH"
     gene            20945..21736
                     /locus_tag="VQ664_000420"
     CDS             20945..21736
                     /locus_tag="VQ664_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2788648.1"
                     /translation="MKIPLLTLARHKFVYVLLTLLFLALVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPIIIVLLGFQYIELKNKVLRLSIG
                     REVSYQGLKRKLTLQVASIPCLIYLVTVLIIAIITYFFGTFSPLEWNSLFSDGSGLQR
                     LLDGEIKSYLFFTCVLLIGIFINAIYFLQIVDYVGNVTRSAITYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILYVVPYMVLKKYEDNV"
     gene            21729..22370
                     /locus_tag="VQ664_000421"
     CDS             21729..22370
                     /locus_tag="VQ664_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2788649.1"
                     /translation="MFKNFNNIWLKRKIVLLLRIVLMMILINYLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEANLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FFDYTRKRLVVISKFFTQDLFVWFLGLLPLGIHFKTVALFFLLAQLMMLYLLLSYLIA
                     LISAGAGFSFFLYFLAFVGQEWMMDHIVTVYLVLLSLLVMLIVSRLEEKFKKG"
     gene            22374..23024
                     /locus_tag="VQ664_000422"
     CDS             22374..23024
                     /locus_tag="VQ664_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2788650.1"
                     /translation="MRLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGDNGSGKTVL
                     LKILAGYIKLDKGKVLQDGKVYGVKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDVEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISEDISDLCTDVLVVENGHIQYVKDIQS"
     gene            23035..23322
                     /locus_tag="VQ664_000423"
     CDS             23035..23322
                     /locus_tag="VQ664_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2788651.1"
                     /translation="MAHLKSFITRYSKVYIGLVLLIWLSFFFIPWDRAILGVRIDIFI
                     MQKILLAFGILSILMALLSKKVSLFVFGLICCLSLWINLFITFAILPIFGN"
     gene            23468..25981
                     /gene="secA"
                     /locus_tag="VQ664_000424"
     CDS             23468..25981
                     /gene="secA"
                     /locus_tag="VQ664_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HET2788652.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMATLTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYAQRYDVITADRDL
                     APEIQAMIKRTIERVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRALKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            26062..27093
                     /locus_tag="VQ664_000425"
     CDS             26062..27093
                     /locus_tag="VQ664_000425"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HET2788653.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            27095..28126
                     /locus_tag="VQ664_000426"
     CDS             27095..28126
                     /locus_tag="VQ664_000426"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HET2788654.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEIFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            28165..28533
                     /locus_tag="VQ664_000427"
     CDS             28165..28533
                     /locus_tag="VQ664_000427"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HET2788655.1"
                     /translation="MRMIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLK
                     GRRQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLS
                     ISHTDQFVTASVILEENHES"
     gene            28523..29626
                     /locus_tag="VQ664_000428"
     CDS             28523..29626
                     /locus_tag="VQ664_000428"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HET2788656.1"
                     /translation="MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVRVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLALPYDLIPALTLESALVHIKTVPAGACMGYGATYQTDSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKPYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            29645..31660
                     /gene="recG"
                     /locus_tag="VQ664_000429"
     CDS             29645..31660
                     /gene="recG"
                     /locus_tag="VQ664_000429"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HET2788657.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     IKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQ
                     LQMLKSENRVQGSGLVLNWSQEKVTAVKVSLPFALTQAQEKSLQEILTDMKSDHHMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLT
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQAYVISPLIEESEALDLKNAIALSEELTTHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIEAWQEDPEWRMIALHLEKKEHLD"
     gene            31976..32956
                     /locus_tag="VQ664_000430"
     CDS             31976..32956
                     /locus_tag="VQ664_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HET2788658.1"
                     /translation="MKNPALLEEIKTYRGRDEVPEDFDAFWDGEVKNVSTLPSYHLEE
                     RDFHIPQVKCYELTFEGSKEGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAMEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVNDQVYNWLCGSEIPFKYLK"
     gene            33761..33988
                     /locus_tag="VQ664_000431"
     CDS             33761..33988
                     /locus_tag="VQ664_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2788659.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            34276..37173
                     /gene="nanA"
                     /locus_tag="VQ664_000432"
     CDS             34276..37173
                     /gene="nanA"
                     /locus_tag="VQ664_000432"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
                     /protein_id="HET2788660.1"
                     /translation="MNRSVQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGESSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKIPRDYYARDLEN
                     VETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDAKAPAFYNLFSVSS
                     ATKKDEYFTMAVYNNTATLEGRGSDGKQFYNNYNDAPLKVKPGQWNSVTFTVEKPTAE
                     LPNGRVRLYVNGVLSRTSLKSGNFIKDMPDVTHVQIGATKRANNTVWGSNLQIRNLTV
                     YNRALTPEEVQKRSQLFKRSDLEKKLPEGAALTEKTDIFESGRNGKPNKDGIKSYRIP
                     ALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGNRVTITNLRDNPKASD
                     PSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKKIDGKTYQILY
                     REGEKGAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGNQLLGNIYFTTN
                     KTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLNGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NRRAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHNGKEYIILSNAGGPNRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWEFLSKDLISPTEAKVKRTREMGKGEMG
                     KGVIGLEFDSEVLVNKAPTLQLANGKTATFLTQYDSKTLLFAVDKEDIGQEIIGIAKG
                     SIESMHNLPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGTEPAVHEIAEYKGSDSLV
                     TLTTKEDYTYKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKREQ"
     gene            38190..38642
                     /locus_tag="VQ664_000433"
     CDS             38190..38642
                     /locus_tag="VQ664_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HET2788661.1"
                     /translation="MIITKISHLGTYVGVNPHFATLIDFLEKTGLENLTEGSIAIDGN
                     RLFGNCFTYLADGQAGAFFETHQKYLDIHLVLENEEAMAVTSPENVSVTQEYDEEKDI
                     ELYTGKVEQLVQLRAGECLITFPEDLHQPKVRINDEPVKKVVFKVAIS"
     gene            38661..39998
                     /locus_tag="VQ664_000434"
     CDS             38661..39998
                     /locus_tag="VQ664_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HET2788662.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            40077..40961
                     /locus_tag="VQ664_000435"
     CDS             40077..40961
                     /locus_tag="VQ664_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2788663.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTVFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            40961..41794
                     /locus_tag="VQ664_000436"
     CDS             40961..41794
                     /locus_tag="VQ664_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET2788664.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAIFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            41812..43905
                     /gene="nanB"
                     /locus_tag="VQ664_000437"
     CDS             41812..43905
                     /gene="nanB"
                     /locus_tag="VQ664_000437"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HET2788665.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQ
                     GGSYQLNNKSIDISPLLLDKLSGESQTVVMKFKADEPNSLQALFGLSNSKAGFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKRSIDEISLFNKAISDQ
                     EVSNIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKIN
                     IATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDK
                     KSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVY
                     DETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSGSLRERHNGKQVPMNVFYKDSL
                     FKVTPTNYIAMTTSQNREESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFAT
                     YTSGELTYLISDDSGQTWKKSSASIPFKNATAEAQMVELRDGVIRTFFRTTTGKIAYM
                     TSRDSGETWSEVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQL
                     VVGLVNKEDDSIDWKYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLS
                     NVVQYIDLEINDLTK"
     gene            43917..45020
                     /locus_tag="VQ664_000438"
     CDS             43917..45020
                     /locus_tag="VQ664_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HET2788666.1"
                     /translation="MVKYGVVGAGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDACKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQPSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVKLSEIVK"
     gene            45194..45892
                     /locus_tag="VQ664_000439"
     CDS             45194..45892
                     /locus_tag="VQ664_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HET2788667.1"
                     /translation="MPQISKEALIEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAA
                     EQGGAVGIRANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIE
                     VIALDCTKRERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTL
                     SGYTSYSPKVDGPDFELIKKLCDAGVDVIAEGKIHTPEQAKQILEYGVRGIVVGGAIT
                     RPKEITERFVASLK"
     gene            45911..>47058
                     /locus_tag="VQ664_000440"
     CDS             45911..>47058
                     /locus_tag="VQ664_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HET2788668.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALVVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETVAGQTVVGAQKIFFAQLADLAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFLGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPFGLIWSV"
BASE COUNT        14314 a         8496 c        10330 g        13918 t
ORIGIN      
        1 tactttcctt attgtctgta aatctactga ccttgttgtt tatcccagtc atggtttcta
       61 gttcgggctc agagtttcaa agtggatggc aagagcatca attgattgct gagaaggtta
      121 gtaaaacact tgataagaca tttgataagg atgtcagaga aattccgacc agtcagtttt
      181 atcaaaaatt tgtagatgag atgggaagga tttactcagg aaatttgatc ctccaggagc
      241 tgataactgt gaatggagct tataaagcta cttatatcgg tgaactctct agcaactaat
      301 cattctttaa aatgatgacc aataagaggc ttgatttggt gaatcaagtc ttttttctct
      361 cttttactgc catttgtgat aaaatagtat agaacgattt tttacatgaa tgataaaaca
      421 gaggtaaata tgacaatcgg tattgataag attggttttg cgaccagtca atatgtcttg
      481 aaattacaag acttagcaga agcgagggga attgaccctg aaaaattaag taaaggactc
      541 ttactcaagg aattgagtat tgcgccccta actgaggaca tcgtgacctt ggcggccagt
      601 gctagtgact ctattttaac tgagcaagaa agacaagaag ttgacatggt cattgtggct
      661 accgagtcag gaattgacca gagtaaggct gcggccgtct ttgtgcatgg cttgctgggc
      721 atccagccct ttgctcgtag tttcgagatt aaagaagcct gctatggggc gacagctgcc
      781 ctccattatg ccaaattgca tgtggaaaat tctccggagt ccaaggtctt ggtcattgcc
      841 agtgatattg ccaaatatgg tattgaaact ccgggagaac caactcaagg tgctggaagt
      901 gtagctatgt tgattacaca aaatccacgc atgatggcct ttaataatga caatgtagct
      961 cagacccgtg acatcatgga tttctggcga ccaaattact cgacaactcc ttatgtaaat
     1021 ggtgtctatt ctacccaaca atacttggat agtttgaaaa cgacttggct tgaatatcaa
     1081 aaacgctacc agcttactct ggatgatttt gcggctgttt gtttccactt gccttatcct
     1141 aaattagcgc taaaaggctt gaaaaaaatc atggataaga gcctgcctca agagaaaaaa
     1201 gacctcttac aaaagcattt tgaccagtct attctctaca gtcaaaaggt ggggaatatc
     1261 tacacaggtt cacttttcct tggacttttg tctctcttgg aaaatgcaga tagcttgaaa
     1321 gctggggata aaatcgccct ttatagttac ggaagtggag ctgtggctga gttcttcagt
     1381 ggtgaattgg ttgaaggata tgaagcttat ttggataaag accgcttgaa caagctcaac
     1441 caacgaactg ccttatccgt tgcagactat gaaaaggtct tttttgagga agtaaacttg
     1501 gatgaaacaa actctgccca gtttgctggc tatgaaaatc aagattttgc cttggttgaa
     1561 attctcgacc accaacgccg ttatagcaag gttgaaaaat aatgaagata agttggaatg
     1621 gattttctaa aaaatcatac caagagcgcc tcgagctgtt aaaagctcag gcgctcctta
     1681 gtcctgagag acaagctagt ctggagaagg atgaacagat gagtgtgact gtggcagacc
     1741 agctgagtga gaatgtagtg ggaacttttt ctctgcctta ttcgctggtt ccggaggtac
     1801 ttgtcaacgg tcaggaatac accgttccct atgtgacaga agaaccctct gtggttgcgg
     1861 cggccagcta tgccagcaaa atcatcaagc gtgcaggtgg ttttactgca caagtccatc
     1921 agcgccagat gattgggcag gtagcccttt atcaagttgc taatcctaaa ctagcgcaag
     1981 agaagattgc cagcaagaaa gcggagctct tggagtttgc caatcaagcc tatccttcta
     2041 tcgttaaacg tggaggtggg gcgcgtgatc tgcatgtcga gcagataaaa ggcgaaccag
     2101 actttctcgt tgtttatatt catgtcgata cccaggaagc catgggtgcc aatatgctca
     2161 acaccatgct ggaagccttg aaaccagtct tagaagaact cagtcaggga cagagtctca
     2221 taggaatcct gtccaactac gcgaccgatt ctctggtgac tgcaagctgt cgcatggcct
     2281 ttcgctactt gagccgccaa aaggatcaag gacgagagat tgcggagaaa attgcgttgg
     2341 ctagtcagtt tgcgcaggct gatccttacc gagctgctac tcataataaa ggaattttta
     2401 atggtattga tgcgattttg attgccactg gtaatgactg gcgtgccatc gaagctgggg
     2461 cccatgcctt tgccagtcga gatggacgct atcaaggtct tagttgctgg acgctggacc
     2521 ttgaaagaga agaattggtc ggtgagatga ccctgcccat gcctgtagcg actaagggtg
     2581 gctctatcgg cctcaaccca cgtgtagctt tcagtcatga tctactagga aatccttctg
     2641 ccagagaatt agcccagatt atcgtgtcca tcggtcttgc ccaaaatttt gcagccctca
     2701 aagctttggt aagtacgggc atccagcaag gccacatgaa actacaggcc aaatccctag
     2761 ctctcctagc tggggctagt gaatctgaag ttgctcccct agtagagcgc ctcatctcag
     2821 ataaaacctt taacctagag acagcccagc gctatctcga aaatttaaga tcataaaaaa
     2881 ctcagacgaa tcggtctgag ttttcttgtg tttaaatact ttttcctggt aatagtgtaa
     2941 ctggtaagaa gtaaccagtt gtggcaactt ccttgccttc aatcttttgc aagagaagat
     3001 caatagtgag acaagcaatc tcttccaaag gttgcttgat agtagccaat tgagggtagt
     3061 aattttcgat aaagtaggtc ccatcatagc cgatgacctt gagctctttt gggacagaaa
     3121 tgcccaattc ttgagcgatt ttaatgacca gaatagctgt caaatcatcc gaagcaaaaa
     3181 tggcatctgg tttttcccgg gtcaagatat tcttgatttc catttctttt ctgacgggag
     3241 aaaagtcact ggaaacattg ataataggag cttttgggag tacggatgca aaaccagcgt
     3301 ggcgtagtcc ggttggcgaa ttggaattgt cattccctgt aatcatgatg atagtctggg
     3361 cacctgtctt gaccaaggtt tgggcagcaa gaaccccacc agcatagttg tcagaggaga
     3421 cgacagggat gtctggcgat aggtttcggt caaaggaaat aatcggcgct gtcacacgat
     3481 tgtagtcttc gattcctagg ttgtgactac cagaaatgat gccgtccacc tgattggctt
     3541 ccaacatttc gatgtattcg cgttccttct cagaatcatg ttcactgttg cagatgatgg
     3601 tcttgtaacc atttttgaag agttggtgtt ccaatttatc aatcaattct gcatagaaaa
     3661 cattggaaat attagggaaa atcaagccga ttaacttagc tgattttcct tgcagactac
     3721 gagccaggtt gttgggttta tagcccaatt ctcgcatggc ttcattgact ttttggatgg
     3781 ttttctcaga tagataccct tttttattga taacccgaga aacggtagta ggactgacgc
     3841 ctgcaagttt ggcgacatca gttagttttg cgaccataat ctaattcata gtaagttcca
     3901 gttgggtttc cagatttgat caggatacca ttttggtccg catgtgggaa gacacgacca
     3961 gaaaatactt tttctccttt attgatgaaa atttcaaaga cagagttatc gatgaagatt
     4021 gtagcagtag tagcctgatt ctcgataggg caagaacgag ttgtcccaaa ttcttgggca
     4081 tactgttctc cagcctggct acgatccact gtcacttgac cgtttacaag gtcaaagttg
     4141 attgaaagtc ccttaccttc tttatcagca agtaagacaa tctcgctctg gctattagct
     4201 tccaagttga gttcaagttc gtaagtgttc ttggtttggg aacggtttga gaaggcttct
     4261 tcagaagcac gaaggtcctt aatagcagcg actggatact ggtagagctt gtcgtctttg
     4321 atagtgagtt ccttgaccaa agagaaggtt ccttggtggt caaaacggtc agatgggtaa
     4381 gaaacatctg gcaaaccaag ccagctaact gctagagcac gcccatcagg agcgttgaag
     4441 gcttgagttg cataggcttc gaaaccgtaa tccatgtttt gaagttgaga cacatctacc
     4501 attttggcat ttttagggtc aaaggaagcc ccaatcttat acatatttgg aaagatatta
     4561 tcgtagtcta gaactttctt atccaatcct tgtggacagt agagaaggac aggatgttcc
     4621 tctacaaaga ccagattagg acattccatc atgtaggcag tacggtcgtt agcaaagtca
     4681 aggtcgccaa ctgcttgcca gtttgtgtag tcgttattga cagccttgta gagacggacg
     4741 aagccttttt tctccaagtc ctgtccaccg acgacagcat agtattgact tttaaagtta
     4801 aaaatttgtg gatcgcggaa gtggtcagta gagtctgctg gctggtcaat caagatcttg
     4861 tcaatctttg taatcttacc ctccttgtcc atcaaagcac cgatctggta tgggtgacgg
     4921 atccagtttt catcgcgaac atttcctgta taaaatagga ataagttatc gccaaattgc
     4981 atggcagaac cagagtaggc accgtggcta tctaatggag tatctggtaa aactttgatt
     5041 ccagtttctt taaagtgaac caaatcatca ctttctagct gtgcccaaga tttcaaaccg
     5101 tgggctgcac caaaaggaaa attctggtaa aagaggatcc acttgccatc aaagtaagaa
     5161 aagccatttg ggtcgttgag aagtcctgtt tttggctcaa catggtaatg agtatgccat
     5221 ggagattgtg ccatattttc ctttatatgt tgaatttctt cttgcgtcca atcttgataa
     5281 agtctgtaac gacgctcagt tgtccattcc attcattcct ccaaaaatct tatcactttt
     5341 aatagtaact gttttcgata aaaaatgcaa gccttttatg ttaaaaaaga ggaaaaactg
     5401 tcaaacgatt atcataaaat aaatacagga aatcaatcaa atttttacga aaatgtgaaa
     5461 gataatgaaa taaaagactt tttaaccaag gtttcaaact tatttttcaa ggaattcctg
     5521 atgaaacagt caaaaacaat caatctaaaa cttgcccact aagtggatag aatatttttt
     5581 ctgcaaaacg cttgacatat ttttaaaaca tgataaaata atagtcgtaa gggcgaataa
     5641 aatcgctttc aaacaagaac aaaatgttat ataaggagat ttttgcaaat gaacaatcag
     5701 gaaattgcaa aaaaagtcat cgatgccttg ggcggacgtg aaaatgtcaa tagtgttgcc
     5761 cactgtgcga ctcgtctacg tgtcatggtc aaagatgaag agaaaatcaa taaagaagtg
     5821 attgagaact tggaaaaagt tcaaggtgct ttctttaact cagggcaata ccaaattatc
     5881 tttggtacag gtacagttaa caaaatgtac gatgaagttg ttgtacttgg cttaccaaca
     5941 tcatctaagg atgacatgaa agcagaagtt gctaaacaag ggaactggtt ccaacgtgct
     6001 atccgtactt tcggtgatgt tttcgttcca atcatcccag ttatcgtagc gacaggtctc
     6061 ttcatgggtg tgcgtggtct tttcaacgct cttgaaatgc cacttccagg tgactttgca
     6121 acttacacac aaatcttgac agatacagcc ttcatcatct tgccaggttt ggttgtgtgg
     6181 tcaaccttcc gtgtatttgg tggaaatcct gccgttggta tcgttcttgg tatgatgctt
     6241 gtctctggct cacttccaaa cgcttgggca gttgctcaag gtggtgaagt aacagcgatg
     6301 aacttctttg gtttcatccc tgttgttggt ttgcaaggtt ccgttcttcc agccttcatc
     6361 atcggggttg tcggagctaa atttgaaaaa gctgtccgca aggttgttcc agatgtcatt
     6421 gacctcttgg taacaccatt cgtgacactt ttggtcatgt ctatccttgg actctttgtc
     6481 attggaccag ttttccacgt tgttgaaaac tacatcctta ttgctacaaa agcgattctt
     6541 agcatgccat ttggtcttgg tggtttcttg attggtgggg ttcaccaatt gatcgtcgtg
     6601 tcaggtgtgc accacatctt caacttgctt gaagtgcaat tacttgctgc tgaccatgct
     6661 aacccattca acgctatcat cacagctgct atgacagctc aaggtgctgc tactgttgcg
     6721 gttggtgtta aaacaaaaaa tccaaaactg aaaacacttg ctttcccggc tgctctttct
     6781 gccttcctag gtattacaga gcctgctatc ttcggggtga acttgcgctt ccgtaaacca
     6841 ttcttccttt cattgattgc tggtgcaatc ggtggtggat tggcttctat ccttggactt
     6901 gctggtactg gtaatggtat caccatcatc cctggtacaa tgctttatgt tggtaacgga
     6961 caacttccac aataccttct tatggtagct gtatcatttg cccttggttt tgctcttact
     7021 tacatgtttg gttacgaaga tgaagtagac gcaactgcag ctgcaaaaca agctgaagtg
     7081 gctgaagaaa aagaagaagt tgcgccagca gctcttcaaa atgaaacact tgtaactcct
     7141 atcgtcggtg atgttgtcgc tcttgctgat gtcaatgacc cagtcttctc aagtggagct
     7201 atgggacaag gtatcgctgt gaaaccaagt caaggcgtgg tctatgcact agctgatgct
     7261 gaagtttcaa ttgcctttcc aacagggcac gcttttggtt tgaaaacaag aaatggtgct
     7321 gaagttttga ttcacgttgg tattgacact gtatctatga acggtgacgg ttttgaagca
     7381 aaagttgctc aaggtaataa ggtgaaagct ggcgatgttc ttggaacatt tgactcaaac
     7441 aaaatcgctg cagctggact tgatgataca acaatggtta tcgttacaaa tacagctgac
     7501 tacgcttcag tagctccagt cgcaacaggt tcagtttcga agggggatgc tgtgatcgaa
     7561 gtgaaaatct aatcaatcct ctctaatgtg aaaacgaaca aatgacatgt ttgttcgttt
     7621 ttattagata gtaagattta cagaggaaaa tctaaaaaat agagacattt agactttcga
     7681 agtatgctat aataaagaaa ataaaaacaa gaggtttatc atgacaaaat tatatggaag
     7741 cttggaagcg ggcggtacaa agtttgtctg tgctgtcggt gatgaaaact ttaacgttgt
     7801 agaaaaaaca caatttccaa caacaactcc aatcgaaaca atcgataaaa ccattgagtt
     7861 cttctcaaaa ttcgataacc ttgctggtct tgcagttggt tcatttgggc cgattgatat
     7921 tgacaaaaac tcaaaaactt atggctttat cacgacgact ccaaaaccaa actgggcaaa
     7981 tgtggacttg cttggtgccc ttcgtcgcgc cctaaacgtg ccaatgtact tcacaacaga
     8041 cgtaaacagc tctgcttacg gtgaaatggt tgctcgtaac aatgctggtg gtcgtatcga
     8101 aaacttggtt tactacacaa tcggtacagg tatcggtgca ggcgtcatcc aacgtggtga
     8161 gtttatcggt ggtgtgggtc accctgaaat gggtcattat tatgttgcta gacacccaat
     8221 ggatattgaa aaagagttta agggtgtttg tcctttccat aagggatgtc tagaaggtta
     8281 tgcagctggt acaagtttgg aagctcgtac aggtgtacgt ggggaaacta ttgaactcaa
     8341 caaccctgtt tgggatgttc aagcctacta tatcgctcaa gctgcggtta atgcgacagt
     8401 gactttccgc ccagacgtga ttgtctttgg tggaggggtc atggctcaac aacatatgct
     8461 ggaccgtgtc cgtgagaaat ttacatctct tcttaatggt tacctaccag taccagatgt
     8521 gcgtgactat atcgtgacgc cagcagtcgc aggaaatggt tctgccacac ttgggaactt
     8581 tgttcttgca aaagaagttt caaaataaag cacaaaatcc gcttgggaaa ccaaacggat
     8641 tttgtggttg aaaacaatat ttttgagcct ttccttaagt gattacggac ggtagcgact
     8701 ttcttcgaaa ttccatacct aaactttgag cctagtgtct caaagtttcc gaatacctga
     8761 aaccattaga tttcaggtgt ttctatcacg gcggaaaggc taggtaagtc ctcgcctcac
     8821 tatcgaaaaa tatgcataat ttccatacca aagtatattt agtatcaagc tatagttaat
     8881 ctacgcttta aaaatccact tgggaaacca aacggatttt ttacgtgtca aagcatttgc
     8941 cagaaaaagt caataatata ggtcagaccg taggtataaa ccacgagggt aaagggtttg
     9001 gtcagaatga tgatagtcat gtagcgcttg aaactcatct tggtcagggc ggccagcata
     9061 cagagaaagt cagctgggct aatgggccaa atcatcataa aaataaagaa gcggtcaaaa
     9121 cgattgccct tatctagcca gccgatgtac ttgtcgtagg tgcgcttgct gacgacagac
     9181 tggacaaagg cagctccgta taggcgcact agataaaaga taatggcaca gccaatcacg
     9241 atgccgatat agttgtagat agtcccgatg atgtgcccgt agataaagac cccagccacc
     9301 gaggtcaagg cccctggaat gatagggacg acagtctgta aaatctgtaa aaagataaag
     9361 agaggtggac cccagatgcc tgcctgctgg ataaaggcag agagggtttc cttggattgt
     9421 aaaatcccag cctgataagc ccaaatacag aaaatcaaac tcccaacccc accgacaatc
     9481 gatgagatat tgataactcg ctgcagaagg ggagaaacag ctttcatttg tttatcctgt
     9541 gacatgtaaa ctcctcatag atagtatatt tctactatac catattttgg aggagaaagg
     9601 gggaatgagt cttttttgat aaggaataga aagtaaatag cccttcgaga cttagaatag
     9661 gtctgtcaac taaaggttat atgcattcta ggtttcgaat aatcgcaatt ccataaattt
     9721 aaaagtattc taagtttcga atagcttatc tgagataatt ttgaggcatt cgcgctttcg
     9781 aatagtcatt ttccctaaag tttatatgta ttctgaagct agaaagacta aaatataaaa
     9841 gtagtaagag tctctctctg atggacgtaa tttatggcta gtatgaatcc tttgaattgt
     9901 tagttaattt taatattaat cagttctgaa ataattacta aatatagtta gatggtgagt
     9961 taattattgc taaatttcaa gttcaagtta gtcatccaga agtcttctct gggggacttg
    10021 tagttcaagc attttttagg atagttgtta atccactttt cgataaatgc gacttccttt
    10081 gtagttgttt tcttagttcc ctgaggtaac catctatgaa tgagcctgtt gtgattttca
    10141 ttagatccta tagtgatgtg cataatagat atagcagatt gaaactagaa tagtatacat
    10201 ctacttctaa aacattgtta gaaatcaatt tgactgtcct gatcaatttg tcctgttttt
    10261 atttcatttt actatataat ccttagaaaa catatcggac aagcggttga attccgttcc
    10321 gtccattagt agataaagga ttactccttc ttgaaatgac agatgaactt gtttcttata
    10381 aaaatgttgt ctgaaactat tagccttttt ccagaagttt tagaggaaga aaactttacg
    10441 aggaaaaagg agttactcaa ataacaattc aggattaaaa atagacagtt gaggagcgga
    10501 aggtataaat taagtttgct actgtataat ggatttatca ctaatactct tcgaaaatct
    10561 cttcaaacca cgtcagcttc gccttgccgt agatatagtt actgacttcg tcagttctat
    10621 ccacaacctc aaaacagtgt tttgagctga cttcgtcagt tttatctgca acctcaaagc
    10681 tgtactttga gcagcctacg gctagcttcc tagtttgctc tttgcttttc attgagtata
    10741 aaagtgctcc aggccatatt ttacacagca atagtcttct aaaaatggac aaaaacattg
    10801 taaaggctat caaaaaggag tataatgagt gcaagaaatt tcggaggtga aagatgctag
    10861 aagtaagaag tctagagaaa agttttggct ccaagcaagt tttgtttggt attgactttc
    10921 aagcgcgacc aggtcgtatt ttgggactag tcggaaaaaa tggtgctgga aaaacaacga
    10981 ttttccatag tattttgaaa ttcctagaat atcagggaga aatcggtctg gatggtcagg
    11041 atattcgtca ggagacctat gctcggattg gttatctgcc tgaagaacgc agtctcatgc
    11101 ctaaattgac agttcttgaa caagttcgct acttggcgac tctaaaaggc atggatgcca
    11161 aagaagtcaa agaaaaactc cctcaatgga tgaagaggtt ggaagtgaaa ggaaagctga
    11221 cagataaaat caagagtctg tcaaaaggaa atcagcagaa gattcagctc attattactc
    11281 tgattcatga accagacctg attatcttgg atgagccttt tagtggattg gacccagtta
    11341 atacagaatt gctcaaacaa gtcatttttc aggaaaaaga gcgcggagca accattatct
    11401 tttctgacca tgtcatgacc aatgttgagg aactttgtga cgatattctg atgatccgag
    11461 atggccgtgt ggtcttgcac ggaccagttc aggatgtccg caatcaatac gggaaaacgc
    11521 gtctctttgt ttcaagtgaa cgaagcaagg aagaattgga aaatcttcct catgtcaaac
    11581 aggtgagctt gaccaaacaa ggcagttgga aattgatttt ggaggatgag agcgctggaa
    11641 gggaactctt cccaatcttg actcaaggtc aatatatcgc aacatttgac caacaagcgc
    11701 caactatcga tgaaatcttt aaactagaat caggagtgga agtatgagaa atatgtgggt
    11761 tgtaatcaag gaaacctatc ttcgacatgt cgagtcatgg agtttcttct ttatggtgat
    11821 ttcgccgttc ctctttttag gaatctctgt aggaattggg catctccaag gttcttctat
    11881 ggctaaaaat aataaagtgg cagtagtgac aacagtgcca tctgtagcag aaggactgaa
    11941 gaatgtaaat ggtgttaact tcgactataa agacgaagca agtgccaaag aagcaattaa
    12001 agaagaaaaa ttaaaaggtt atttgaccat tgatcaagaa gatagtgttc taaaggcagt
    12061 ttatcatggc gaaacatcgc ttgaaaatgg aattaaattt gaggttacag gtacactcaa
    12121 tgaactgcaa aatcagctta atcgttcaac tgcttccttg tctcaagagc aggaaaaacg
    12181 cttagagcag acaattcaat tcacagaaaa gattgatgaa gccaaggaaa ataaaaagtt
    12241 tattcaaaca attgcagcag gtgccttagg attctttctt tatatgattc tgattaccta
    12301 tgcgggtgta acagctcagg aagttgccag tgaaaaaggc accaaaatta tggaagtcgt
    12361 tttttctagc ataagggcaa gtcactattt ctatgcgcgg atgatggctc tgtttctagt
    12421 gattttaacg catattggga tctatgttgt aggtggtctg gctgccgttt tgctctttaa
    12481 agatttgcca ttcttggctc agtctggtat tttggatcac ttgggagatg ctatctcact
    12541 gaataccttg ctctttattt tgatcagtct tttcatgtac gtagtcttgg cagcattcct
    12601 aggatctatg gtttctcgtc ctgaggactc agggaaagcc ttgtcgcctt tgatgatttt
    12661 gattatgggt ggtttttttt gagtgacagc tctaggtgca gctggtgaca atctcctctt
    12721 gaagattggt tcttatattc cctttatttc gaccttcttt atgccgtttc gaacgattaa
    12781 tggctatgcg gggggagcag aagcatggat ttcacttgct attacagtga tttttgcggt
    12841 ggtagcaaca ggatttatcg gacgcatgta tgctagtctc gttcttcaaa cggatgattt
    12901 agggatttgg aaaaccttta aacgtgcctt atcttataaa tagaagagcc ttgcgaaagc
    12961 gaggttttta aaggtgaaaa gggtggaatc acgaacctaa tgatgtacac attatgtaaa
    13021 caggttgctt gaaaactcaa ttgtatagtg aactgaatct ggaataggat aatattactt
    13081 ctaaaacatt cttataaatt gatttgaatt ccaaaatccc atcgttccgt tcttatttca
    13141 ttttgcgata tagtgaaagg aaataagtca gctcacaaaa aacgcataat atcaaggatt
    13201 tttaacactt gatactatgc gttttctaat tttaaagact ttttgcctgg tctcttttgt
    13261 tctatgagta tgttacatat ctaggtaaaa attatttaaa gcaaattaac cttatttctc
    13321 aagatgtagt aggttccgag ataaaagata gctatgaata tgagttcttt aacaatggct
    13381 atacctgctc ccatatagaa atggtcattg agtcctacca gtgaattgac atagaaatta
    13441 gaactaagat tgaagaaaag ttcaataaat ccaatgacga tttggatacc aatgtaggct
    13501 gcaacagcga gtgctgtacg gtattcattg aaaagctgtc caatggaaat agccaggtag
    13561 atgcagagga ttcctgaaat ggtatttagt aggaaggata tacctgtaag aaagatctga
    13621 gggagatgtg tttctacaaa tgtaatcaca taagaaagag gaatccattc tggagctgtt
    13681 aaagccagaa taataacagc acttagagcc aatacagcgg tgctaatcaa tgaccagata
    13741 aaggcaccga ttagtttggc tgtgatgata tggtgttcag aaactggcaa ggtcaaagtc
    13801 agatagcctt gtcggtcgta gacactacct ttgaagcgtt taataatcaa gaaaatggtt
    13861 gaaatcgcaa gtgtaagcat caagccacca aagactgtag ctagaaaaag tagcatagta
    13921 gcctgacttt cttggtaagg tagattttta aagccttgtg tctgtattcc gatgagggca
    13981 gaaaggacta gcacggctgc gtagagggct aaataccact tgttaacatt tttaaattcg
    14041 tagtgaacta aattccaaaa cataaataat ctcctttgct taggccttaa attcctgacg
    14101 gaagagttgg tcaatggatt cacctgactc gtagcgaata tcatctacat ttccttgacg
    14161 gacgactttt ccgtctttta ggaagacaat ttcatccaag attggctcga tatcagaaat
    14221 caagtgggta gaaatcaaaa cggtagaagt tggtgagtag ttgttgataa tggtattgag
    14281 gatataagca cgggctgctg gatccacccc accaatgggt tcatccaaaa catagagacg
    14341 agcatcacgg ctcataacca aaatcagttg aaccttttct ttgtttcctt ttgatagttt
    14401 cttgagacga ctattttcat caatgcccag gtctgcaagt agatgatgag cgcgttcaag
    14461 attgaaatct ttatagaagg tcttgaagta ggttagggct tctttgacct tcatttgctc
    14521 attgagatag gtcgtatcag gcaaataagc tacaacggcc ttggttgctg ggcttgggtc
    14581 catgtcgttg atgaggacac gtccttgatc tggttgtaag aggccattaa ttagtttaat
    14641 cagggttgtt tttcctgagc cgtttggccc aagaaggccg acaatttttc cagctggaat
    14701 gtcaagagaa acattttcaa gggctggtgt tgctccatat gatttggata cattttcaaa
    14761 tactagtaat gacataggct taaactcctt taatataatc actgactacg cctggtagtt
    14821 cttctttttc atagccaaaa tggatcatgg aggaaacgaa gtgttccaat tcttcttctg
    14881 ataattgttt gcgtgactga gcgattagct ccttatcctt agtcacaaat cgtccagttg
    14941 ttcgcttgct gtagacaaat ccttctcgtt caaggtctga taaggctctt tggatggtat
    15001 tgggattgac accagcctcg ctagctagct ccctcacggt tggaagttgt tgattgggtt
    15061 ccagtgtatg ggaaacaatc tgaagcttga ttttctccat aatctgtaaa tagatgggtt
    15121 ttttgttgtc aaatgtccag gacatcttag tctcctttct cttatccttt tgtcttaact
    15181 aaataataca acaaaacaaa aaacttgtca agcaaaaaga agaattgttt tgggaatcgc
    15241 ttaaaaaatg gtataatgaa aagaaaacga taaggaggga aaggatgcgt tgtccaaaat
    15301 gtggggctac caagtcaagt gttatcgata gtcgccaagc agaagaaggg aacaccattc
    15361 gtagaagacg tgagtgcgac gaatgccaac accgttttac aacctacgaa cgagtagaag
    15421 aaagaacctt agtggttgtt aaaaaagatg gtacacggga acaattctcc agagataaaa
    15481 tctttaatgg gattatccgc tcagcccaga aacgtcctgt gtcaagtgat gaaatcaaca
    15541 tggtagtcaa tcgtatcgaa cagaaactcc gtggtcgaaa tgaaaatgaa attcaaagtg
    15601 aggacattgg ttcactcgtc atggaggagt tggctgaatt ggacgagatt acctatgtac
    15661 gttttgctag tgtctatcgt agttttaagg atgtcagtga gttagagagc ttgctccaac
    15721 aaatcaccca gtcctctaaa aagaaaaagg aaagataaat gaagccaatt gaccgttttt
    15781 cttatctaaa gaataatcgg gtgtcgcaag atacctcatc tctggtacag tgctacctcc
    15841 cgattatcgg tcaggaggca ctgagccttt atctttatac aatcagtttt tgggataatg
    15901 gtagaaagga atatcttttt tcaagtatcc tcaatcatct caactttggg atggatagac
    15961 tgataaaatc attgaaaatc ttatctgctt ttaatctctt gaccctctat caaaaggggg
    16021 atgtttatca gctagccctc catgctcctc tatctagtca agacttcttg gagcatcctg
    16081 tttatcgcag actcttagag aaaaagattg gcgactctgc tgtggaggat ttgaaagttg
    16141 aaagtgctga tggtgaagaa atacctgtct cactcaatca agtctttcca gaattggcag
    16201 aactaggcag tcaagaagac cttggtctca agaagaaagt ggccaatgat tttgacttgg
    16261 aacattttcg ccagctgatg gctcgagatg gacttcgttt tgcggatgag cagtccgatg
    16321 tcttaaacct ctttgctatt gccgaggaga agaaatggac ttggtttgaa acctatcaat
    16381 tggccaagtc aacagctgtt tctcaggtta tttcaaccaa acgcatgcgt gaaaaaattg
    16441 ctcaaaaacc agtttcctct gactttaatc ctaaggaagc aaccattatc aaggaagcta
    16501 aaagtaagac tgccctgcag ttcttagcag aaatcaagca aacacgcaag gggaccatta
    16561 cccaaacaga aagagaactt ttgcaacaga tggctggctt gggcttgctg gacgaagtca
    16621 tcaatatcat tctcttgttg acctttaata aggtggattc ggcaaacatc aatgagaaat
    16681 atgccatgaa ggtggctaat gactatgcct atcaaaagat acattcagca gaagaggccg
    16741 ttttacgaat tcgtgagcga gggcagaaaa caaaaacaca aaaacagaat cagactgccc
    16801 cagcaaaaac caatattcct aaatggagta acccagatta taagaatgaa accagcgagg
    16861 aaactcgtct ggaactagaa cgtaagaaac aagaactatt agctcgatta gaaaaaggag
    16921 gagattagat ggaaagtgtc ggagacgtac tcaaacgtca acccagccgt ttttattatc
    16981 aagatttggt ccagaaaatc atgaaggacc ctgatgttgc ggcttttatc cagcaagaat
    17041 ccttgactcc agaggaatta aatcgcagta tctccaagtt taatcagtac atcaccgagc
    17101 gtgacaagtt tctccgtggg gatacggatt atattgccaa aggctacaag ccgattttgg
    17161 ttaagaatca tggctatgca gatgtttcat atgaagaaac tcctgagcta atcgcggctg
    17221 aaaaagaagc ggctattaag aatcgtctca agctaatcaa tctaccagcc agtctcaaaa
    17281 aagctagttt ggctcaagtt gatttggatg atttgggacg cttgccagtt tttgaaaaac
    17341 tattagcctt tgtggagcaa tatccagcta ttcgaaaagg tctttactta tatggagact
    17401 ttggtgtggg taaaagtttc atggtggcgg ccttagctca tgatttatca gaaaaacgtg
    17461 gtgtttcatc aactctcctc cactatccta gctttgtcat tgatgtcaaa aatgctatca
    17521 gtgatggcaa tgttaagacc ttggtggatg agattaagct gtctgaggtc ctgattttag
    17581 atgatattgg cgccgagcaa tcaaccgctt gggtgcgtga cgaaatcctg caggtcattc
    17641 tccaatatcg gatgcaggaa aatttaccga cctttttcac atccaacttc aactttgaag
    17701 atttggagaa gcattttgcg aaagtgaaac atggaaatga cgaaacctgg gaagccagac
    17761 gggtcatgga acgcatccgt tatttggctg aggagactcg tttagaagga gtaaaccgtc
    17821 gatgacagaa accattaaat tgatgaaggc tcatacttca gtgcgcaggt ttaaagagca
    17881 agaaattccc caagtagact taaatgagat tttgacagca gcccagatgg catcatcttg
    17941 gaagaatttc caatcctact ctgtgattgt ggtacgaagt caagagaaga aagatgcctt
    18001 gtatgaattg gtacctcaag aagccattcg ccagtctgct gttttccttc tctttgtcgg
    18061 agatttgaac cgagcagaaa agggagcccg acttcatacc gacaccttcc aaccccaagg
    18121 tgtggaaggt ctcttgatta gttcggtcga tgcagctctt gctggacaaa acgccttgtt
    18181 ggcagctgaa agcttgggct atggtggtgt gattatcggt ttggttcgat acaagtctga
    18241 agaagtggca gagctcttta acctacctga ctacacctat tctgtctttg ggatggcact
    18301 gggtgtgcca aatcaacatc atgatatgaa accgagactg ccactagaga atgttgtctt
    18361 tgaggaagaa taccaagaac agtcaactga ggcaatccaa gcttatgacc gtgttcaggc
    18421 tgactatgct ggggcgcgtg cgaccacaag ctggagtcag cgcctagcag aacagtttgg
    18481 tcaagctgaa ccaagctcaa ctagaaaaaa tcttgaacag aagaaattat tgtagaaagt
    18541 gagaaattat ggccctacca actattgcca ttgtaggacg tcccaatgtt gggaaatcaa
    18601 ccctatttaa tcggatcgct ggtgagcgaa tctccattgt agaagatgtc gaaggagtga
    18661 cacgtgaccg tatttatgca acgggtgagt ggctcaatcg ttcttttagc atgattgata
    18721 caggaggaat tgatgatgtc gatgctcctt tcatggaaca aatcaagcac caggcagaaa
    18781 ttgccatgga agaagcagat gttatcgtct ttgtcgtgtc cggtaaggaa ggaattaccg
    18841 atgcagacga atacgtagcc cgtaagcttt ataagaccca caaaccagtt atcctcgcag
    18901 tcaacaaggt ggacaaccct gagatgagaa atgatatcta tgatttctat gctctcggtt
    18961 tgggtgaacc attgcctatc tcatctgtcc atggaatcgg tacaggggat gtgctagatg
    19021 cgatcgtaga aaatcttcca aatgaatatg aggaagaaaa tccagatgtc attaagttta
    19081 gcttgattgg tcgtcctaac gttggaaaat caagcttgat caatgctatc ttgggagaag
    19141 accgtgttat tgctagtcct gttgctggaa caactcgtga tgccattgat acccacttta
    19201 cagatacaga tggtcaagag tttaccatga ttgatacggc tggtatgcgt aagtctggta
    19261 aggtttatga aaatactgag aaatactctg ttatgcgtgc catgcgtgct attgaccgtt
    19321 cagatgtggt cttgatggtc atcaatgcgg aagaaggcat tcgtgagtac gacaagcgta
    19381 tcgcaggatt tgcccatgaa gctggtaaag ggatgattat cgtggtcaac aagtgggata
    19441 cgcttgaaaa agataaccac actatgaaaa actgggaaga agatatccgt gagcagttcc
    19501 aatacctgcc ttacgcaccg attatctttg tatcagcttt aaccaagcaa cgtctccaca
    19561 aacttcctga gatgattaag caaatcagcg aaagtcaaaa tacacgtatt ccatcagctg
    19621 tcttgaacga tgtcatcatg gatgccattg ccatcaaccc aacaccgaca gacaaaggaa
    19681 aacgtctcaa gattttctat gcgacccaag tggcaaccaa accaccaacc tttgtcatct
    19741 ttgtcaatga agaagaactc atgcactttt cttacctgcg tttcttggaa aatcaaatcc
    19801 gcaaggcctt tgtttttgag ggaacaccga ttcatctcat cgcaagaaaa cgcaaataaa
    19861 aaagtagaat ctggaatgac agttccggat ttttttgata taataaaata atagaaaacg
    19921 ctatcaaaag aaggagggtg atgtcggtga tggaacattt gtttaaattc ttacttttag
    19981 caccgtactt ttattttgat aactggattg agaaggccaa cagaaatagt aagttttttc
    20041 caatttttta ttatttttac tggttttaca tccccttcta ttctcttttt agccttgctt
    20101 ggacagttgt ttcagttctg tttttcaata ccgtcttgag aaatgtgaca gatatcaagt
    20161 tatggggcat ttggtttctt tttattctgc tagctattgg tatgaattgg ttaacttatt
    20221 cctgtttcaa agaaatgttt cgcttgagac aggaactagg gaagtctaag ggtggaaggc
    20281 attgatttat atcggtttct atttgtagga ggtggcttat ggtacctcta aaatcattta
    20341 ttacacgcta ttccaaggtt tatattggta ataacattta atagaacgaa actaaagaaa
    20401 acaatttaaa agaggaggtt tgtgatggaa tacttgttta aaatgataat cttattaccc
    20461 tgtttttact ttttcagctg gattgaaaag gcaaacagag atagtaagat tttcccaatt
    20521 ttttactatt tttactggat ttacatcacc ctctatgctc tttttagcct tgcttggaca
    20581 gttttttcag ttctgttttt caatatcgtc ttgagaaatt tgacagatat caagttatgg
    20641 ggtatttggc tattattact acttatcgct tttgctagtg actggttaga ctatatctgt
    20701 ttcaaaaaaa tgcttgactt gagacgggaa ctagggaagt ctaaaggcgg aaggcattga
    20761 tttatactct tcgaaaatct cttcaaacca cgtcaacgtc gccttggatt atatatgtaa
    20821 ctgacttcgt cagtcttatc tacaacctca aagcagtgct ttgagcaact tgcggctagt
    20881 ttcctagttt gctctttgat tttcattgag tattatatta ctttctattt gtaggaggtg
    20941 gcttatgaag attcctctct taactttggc aaggcataaa tttgtttatg tcttgcttac
    21001 tttgcttttt cttgctttgg tttatcgtga tgttttgatg acttatttct tttttgatat
    21061 tcatgcgccc gatctagcta aattcgatgg acaagcaatt aaaaatgact tattaaaatc
    21121 agcattagat tttcgtattc tccagttcaa tctaggtttt tatcaatcat ttattattcc
    21181 aatcatcatt gttttgctag gttttcaata tattgagctg aaaaataaag ttttacgatt
    21241 gagtattgga agagaagtga gctatcaagg gttaaaaaga aagttgactt tgcaagttgc
    21301 aagtatccct tgtttgatat atttagtgac tgtgctgata attgcaatta taacctattt
    21361 ctttgggact ttttctcctc ttgaatggaa ttctctattt tctgatggga gtggtttaca
    21421 aagactccta gatggagaga taaaaagcta tttgttcttt acttgtgtcc tactaatcgg
    21481 tattttcatc aatgcaatct attttttaca aatagttgat tatgtgggga atgtgactcg
    21541 ttcggcaatc acctatttga tgtttctttg gcttggttct atgctgctct atagtgcctt
    21601 gccttactat atggttccta tgacgagttt gatgcaagct agctatgggg atgtaagttt
    21661 gatgaaactc tttactcctt atatccttta tgttgtccct tatatggtac ttaaaaaata
    21721 tgaagataat gtttaagaat tttaacaata tttggctaaa gagaaagatc gttttactac
    21781 ttcgtatagt tctgatgatg attttgataa actatctatt gtcaacagcg gttcaaaagc
    21841 aggatgctgt tatctttttc aagagagaat tgatttcaat tttttcctat aatgactatt
    21901 ctgaagcgaa tttagaaatc cccaaactct tgttaaacct ttcgcttttc atggtaggat
    21961 ggctctctgt cattttactt gaaagtgatt tggcagacca ttaccatcac ttgattcgct
    22021 atcaatcaag ctcctttttc gattatacaa ggaaacgatt ggttgtcatt tctaaatttt
    22081 ttactcaaga tttgtttgtc tggtttcttg gtttacttcc gctaggaatt catttcaaaa
    22141 cagtcgcact tttcttttta cttgctcagt taatgatgtt gtacttacta ctgtcttatc
    22201 tgatagcact gattagtgcg ggcgctggtt tttctttttt tctctatttt ttggcatttg
    22261 tgggacaaga atggatgatg gatcatattg taacagtgta tttagtactc ttaagcttat
    22321 tagttatgtt gattgttagt cgcttggaag agaaatttaa gaaaggataa acgatgagac
    22381 ttgaaattat aaatggacag aaaatttatg ggaaaagacc tattttaaat cagttgaatt
    22441 tggtgtttca atcaggaaaa atttatggac ttaaaggtga taatggatct ggcaagacgg
    22501 ttcttttaaa gatacttgct ggttatatta agcttgacaa aggaaaagtt cttcaagatg
    22561 gtaaagttta cggggtaaaa aatcattata ttcaggatgc aggaatttta attgaaaaag
    22621 tcgagttttt atctcattta tccctgagag aaaatttgga actgttaagg tatttttcat
    22681 ctaaagttac ggaaaaaaga attgcctatt ggattcaata ctatgattta caggaatttg
    22741 aagacgttga ataccgtcat ttatccttgg gaacaaagca aaaaatggcc ttgattcaag
    22801 cctttatttc ctctccttct atactctttc tcgatgaacc tatgaatgct ttggatgaga
    22861 agagtgtgag gttaaccaaa caggtcattt tatcttacct gaaaaaagaa aatggtctgg
    22921 ttatcctgac gtcgcacata tcggaagata tttcagacct ttgtacagat gtattagttg
    22981 tcgaaaatgg acatatacaa tatgtaaagg atatacaatc ctaggagatg gcttatggca
    23041 catctaaaat catttattac acgctattcc aaggtttata ttggtttagt tctgctgatc
    23101 tggctgtctt tcttctttat cccttgggat agagcgattc tgggggtaag gattgacatc
    23161 ttcatcatgc agaaaatctt gctagctttt ggaattctgt ccattctcat ggccttgctg
    23221 tccaagaaag tcagtctctt tgtttttgga ctgatttgct gtctttctct ttggattaac
    23281 ttatttatca catttgccat tttgccgatt tttggcaatt aaacagtcat aaaagtcgga
    23341 gaggttagct tgaaaactaa cctctttttc cttttcaaaa tggggattct tccttgaaaa
    23401 taatcagtaa ttgtgctaaa attaaaggaa cattctaaaa tattcggaat ttaaagtaag
    23461 gaaaaacatg gctaatattt taaaaacaat tatcgaaaat gataaaggag aaatccgtcg
    23521 tctggaaaag atggctgaca aggttttcaa atacgaagac caaatggcta ctttgactga
    23581 cgaccaacta aaagcaaaaa cagttgaatt taaggaacgt tatcaaaatg gagaatcact
    23641 ggattcattg ctttacgaag catttgcggt tgtccgtgaa ggtgccaaac gtgtcctagg
    23701 tctcttccct tataaggttc aggtcatggg ggggattgtt cttcaccatg gtgacgtgcc
    23761 agagatgcgt acaggggaag ggaaaacctt gactgcgacc atgccggtat acctcaatgc
    23821 cctttcaggt aaaggggttc acgtagttac ggttaatgaa tacctgtcag aacgtgacgc
    23881 gactgagatg ggtgaattgt actcttggct tggtttgtca gtagggatta acttggctac
    23941 caaatctcca atggagaaaa aagaagccta tgagtgtgat attacttact caactaactc
    24001 agaaatcgga tttgactacc ttcgtgacaa catggtcgtt cgcgccgaaa acatggtaca
    24061 acgtccgctt aactatgcct tggtcgatga ggttgactct atcttgattg acgaggctcg
    24121 tacacctttg attgtatcag gtgccaatgc ggttgaaacc agtcagttgt atcacatggc
    24181 agaccactat gtaaaatctt tgaacaaaga tgactacatc atcgatgtgc agtctaagac
    24241 tattggtttg tctgattcag ggattgacag ggctgaaagc tacttcaaac ttgaaaacct
    24301 ctatgacatc gaaaacgtgg ctttgactca ctttatcgat aacgcccttc gtgccaacta
    24361 catcatgctt ctcgatattg actatgtggt gagcgaagag caagaaatct tgattgtcga
    24421 ccaatttaca ggtcgtacca tggaaggtcg tcgttattct gatggattgc accaagctat
    24481 tgaagccaaa gaaggtgtgc caatccagga tgaaaccaag acatctgcct caatcacgta
    24541 ccaaaacctt ttccgtatgt acaagaaatt gtctggtatg acgggtacag gtaagactga
    24601 ggaagaagaa ttccgtgaaa tctacaacat tcgtgttatt ccaatcccaa caaaccgtcc
    24661 tgttcaacgt attgaccact cagaccttct ttatgcaagt atcgaatcta agtttaaagc
    24721 ggttgtcgaa gacgttaagg ctcgttacca aaagggtcaa cctgtcttgg ttggtacagt
    24781 agcggttgaa actagtgact acatttctaa gaaattggtt gcagctggtg ttcctcacga
    24841 agtcttgaat gccaaaaacc actatagaga agcccaaatc atcatgaatg ctggtcaacg
    24901 tggtgccgtt accatcgcaa ccaacatggc gggtcgtggt accgacatca agcttggtga
    24961 aggtgttcgt gaacttggag gactttgtgt tattggtaca gaacgtcatg aaagtcgtcg
    25021 tatcgataac cagcttcgtg gacgttcagg tcgtcaagga gatccaggtg agtcacaatt
    25081 ctacctatct cttgaagatg atttgatgaa acgttttggt tctgaacgct tgaagggaat
    25141 ctttgaacgt ttgaacatgt ctgaagaggc gattgagtct cgcatgttga cgcgtcaggt
    25201 tgaagcagct cagaaacgtg tcgaaggaaa taactacgat acccgtaaac aagtccttca
    25261 atacgatgat gtcatgcgtg aacaacgtga gattatctat gctcaacgtt acgatgtcat
    25321 cactgcagat cgtgacttgg cacctgaaat tcaggctatg atcaaacgca cgattgaacg
    25381 tgtcgttgat ggtcatgcgc gtgccaaaca agatgaaaaa ctagaggcaa ttttgaactt
    25441 tgctaagtac aacttgcttc ctgaagattc tattacgatg gaagacttgt caggcttgtc
    25501 tgataaggcc atcaaggaag agcttttcca acgtgccttg aaggtttacg atagtcaggt
    25561 ttcaaaacta cgcgatgaag aagcagttaa agaattccaa aaagttttga ttctacgagt
    25621 ggtggataac aagtggacag atcatatcga tgcccttgat caattgcgta acgcggttgg
    25681 acttcgtggc tatgctcaga acaaccctgt tgttgagtat caggcagaag gtttccgtat
    25741 gtttaatgat atgattggtt cgattgagtt tgatgtgaca cgcttgatga tgaaagcaca
    25801 aattcatgaa caagaaagac cacaggcaga acgtcatatc agtacaacag cgactcgcaa
    25861 tatcgctgct caccaagcaa gtatgccaga agatttggat ttgagccaga ttggacgcaa
    25921 tgaactttgc ccatgtggtt ctggtaagaa atttaaaaac tgtcacggta aaagacaata
    25981 aaatgagata gtttagaggc ggatatcttg tgaaaagtaa atttttactg ggtatccgtt
    26041 tgctttataa ggagatgagt tatggtattt acagcaaaaa gctctaaaat aaatatagaa
    26101 gaagttcgtg ccttgtcaaa attagaaggt caggctttgg agaggaaatc acagcgcgat
    26161 caagagctag aagccattat acgtggagaa gatcagcgaa ttctcttggt aatcgggcca
    26221 tgctcatctg acaacgaaga agctgtcctt gaatacgcta agcgtttggc agtcctacaa
    26281 gaagaagtgg cagatcgtat ctttatggtt atgcgtgttt atactgccaa accccgtacc
    26341 aacggagatg gctataaggg cttgattcac cagcctaacg cgacagaagc gcctagtctt
    26401 atcaatggaa tcaaagccgt tcgccatctt cactatcgtg tcatcacaga aacagggatg
    26461 acaactgctg atgaaatgct ttatcctgaa aaccttccgc ttgtagatga tttgatttct
    26521 tacatggcag ttggtgcccg ttcagttgaa gaccagcaac accgctttgt ggcaagtggg
    26581 gcaggatttt ctactggttt taaaaatcca acctctggaa atctcaatgt catgtttaat
    26641 gggatttatg ctgctcaaaa caaacaaagt ttccttttct taggaaaaga agtagaaaca
    26701 actgggaacc cgctttcaca cgctattctt cgtggtgctc ttaatgagta tggaaaaaat
    26761 attcccaact actattatga caatttaatt gataccattg cccaatatga gaaaatgggc
    26821 ttggaaaatc cttttatcat cattgatacc aatcatgaca attctggtaa gcagtatatt
    26881 gaacagatcc gaattgtccg ccagaccttg attaaccgtg cttggaatga aaaaattaag
    26941 cagttcgttc gtggttttat gattgagtct tatctggaag atggtcgaca aaatgagcca
    27001 gaagtatttg gcaagtctat cacagaccct tgcctgggtt gggataacac agaagctctt
    27061 gtcagagaaa tttacaaaac gttaggagaa taagatggca tttattgaaa aaggtcaaga
    27121 aatcgatatg gaagtcatca aggctgaaac ccaattgtct gcggaagcct tgagactcaa
    27181 ggaaagccgt gacagggaat tggcagatat tatttcaggg gaagatgacc gtattctctt
    27241 ggtgattggt ccttgctctt ctgataatga agaggcggtc ttggaatatg ctcgccgttt
    27301 atccgccttg caaaagaagg tagcggacaa gattttcatg gtcatgcgcg tgtatactgc
    27361 taagcctcgt accaatggag acggctataa aggattggtt caccagccag atacttctaa
    27421 ggctccaagc ctgattaacg gtttgcaggc tgtgcgccag ttgcattacc gcgtgattac
    27481 agagactggt ttgacaacgg cagatgagat gctttatccg tcaaatctga tcttggtgga
    27541 tgacttggtc agctaccatg ccgttggagc tcgttctgtg gaagaccaag agcaccgctt
    27601 tgtggcttct gggattgatg caccagtagg gatgaaaaat ccaacctcag gaaatttggg
    27661 tgttatgttt aacgccatct atgctgctca aaacaagcaa accttccttt atcatgggca
    27721 ggaagttgag acatcaggta atcctttggc ccatgttatc ctccgtggag cagtcaacga
    27781 gtatggcaat tatatgccga attactacta tgaaaaccta ctccaagcca ttgaacgcta
    27841 tgaaaccatg ggacttgaaa atccttttat cctcattgac accaaccatg ataactcagg
    27901 caagcaatat atggagcaga ttcgaattgt tcgccagacc ttgcagaatc gtgattggaa
    27961 tgagaaaatt aaaaagacgg ttcgaggatt tatgattgaa tcttacctag cagatggtcg
    28021 tcaaaaccaa ccagagatct ttggttgctc tattactgac ccttgcctag gttgggaaaa
    28081 tacagaggcc ttggtagaag agatttatgt taccttgaca aaataagtga aaaggatgga
    28141 gttggggaat ctcaactcct tttgatgaga atgatagttg gacacggaat tgacatcgaa
    28201 gaattggctt cgatagaaag cgcagttaca cgacatgaag gatttgctaa gcgtgtactg
    28261 accgctcagg aaatggagcg cttcaccagt ctcaaaggac gcaggcaaat agaatattta
    28321 gctggtcgct ggtcggctaa ggaggccttt tccaaggcta tgggaacggg cattagcaag
    28381 ctcggttttc aggatttgga agtattgaac aatgaacgtg gggcgcctta ttttagtcag
    28441 gcaccatttt caggaaagat ttggctgtct atcagccaca ccgatcagtt tgtgacagcc
    28501 agtgtcattt tggaggaaaa tcatgaaagc tagtccacat agaccaacca aggctctgat
    28561 tcatctggga gctattcgac aaaatattca gcaaatgggg gctcatatcc ctcaaggaac
    28621 gctcaagttg gctgtggtta aggccaatgc ttatggtcat ggagctgttg ccgttgccaa
    28681 ggcaattcaa gatgatgttg atggcttttg cgtttccaat atcgatgaag ccattgaact
    28741 cagacaagct ggactcagca agccaatcct cattttagga gtttctgaaa tcgaagctgt
    28801 tgctctagct aaagaatatg acttcacctt gacagtggct ggactggagt ggattcaagc
    28861 actcttagat aaggaagtgg acctaactgg attgacagtc cacctcaaga ttgattcagg
    28921 gatgggacgg attggtttta gagaggcaag tgaggttgag caggctcaag atttgctcca
    28981 acaacacggt gttcgtgttg aaggaatctt tacccacttt gctactgctg atgaggaatc
    29041 agatgactat tttaatgccc agttagaacg gtttaaaact attttagcta gtatgaagga
    29101 agttccagag ctggttcatg ctagcaattc tgcaacgact ctttggcatg tagagactat
    29161 tttcaatgcg gttcgtatgg gagatgccat gtatggtctc aatccaagtg gagcggtctt
    29221 ggctttgcct tatgatttga taccggcctt gaccttggag tctgctctgg ttcatatcaa
    29281 gacagttcca gctggtgctt gcatgggcta tggagcaact tatcaaacgg atagcgagca
    29341 agtcatcgcg accgtgccaa tcgggtatgc agatggatgg acaagagaca tgcaaaattt
    29401 ctctgtcttg gtagatggcc aagcttgccc aattgtcggc agggtttcga tggaccaaat
    29461 cactattcga ttgcctaagc cttacccact cggaaccaag gtaaccttga ttggctccaa
    29521 tggggataag gaaatcactg caactcaggt agcgacctac cgcgtaacca ttaactatga
    29581 ggtggtttgc ctcctcagcg accgtattcc gagagaatat tactagaaaa gaaaggagtg
    29641 gagcatgaat ctacatcaac ccttgcatgt cttgcctggt gtgggaccaa agtcagcaga
    29701 aaaatacgcc aaactaggaa ttgaaaactt gcaagatctc ttgctctact ttcctttccg
    29761 ttatgaagac ttcaaaatca agcaggtgct ggagctggaa gacggtgaga aggcagttct
    29821 ttctggtcag gtagtgactc ctgctagtgt ccagtattat ggtttcaagc gcaatcgcct
    29881 gcgttttagt ctcaagcagg gagaggtcgt ttttgcggtg aatttcttta accagcccta
    29941 tctggctgat aaaatagagt tgggagcaac ccttgctgtc tttggaaaat gggaccgcgc
    30001 taaggctagt ctgactggga tgaaggttct ggctcaggta gaagatgacc tccagcctgt
    30061 ctatcgtctg gctcagggaa tcagtcaggc cagtctggtt aaggtcatca agacggcttt
    30121 tgatcaggga ctggacctct tgatagaaga aaatctgccc cagtctttac tagacaaata
    30181 caaactcatg tcccgttgtc aggcagtccg agctatgcat tttccaaagg atttggcaga
    30241 atacaagcag gctcttcgcc gtatcaagtt tgaggaactc ttttatttcc aaatgcagct
    30301 gcagatgctc aagtctgaaa atagagttca gggaagtggt ctggttctga attggtctca
    30361 ggaaaaagtg acagcagtta aagtaagtct tccttttgcc ctgacccaag ctcaggaaaa
    30421 gagtttgcag gaaattttaa ctgatatgaa gtccgaccac cacatgaatc gtctcctaca
    30481 aggggatgtg gggagtggaa aaacggtagt cgctggcttg gccatgtttg cggcagtgac
    30541 agcaggttat caggctgccc taatggtacc aacagaaatc ctcgcagagc aacactttga
    30601 gagtttacag aacctttttc ccaatttgaa actggctctc ttgacaggtt ccttgaaagc
    30661 tgcagaaaag agagaggtct tggagaccat tgccaagggt gaggctgatt tgattatcgg
    30721 aactcacgct ctgatacaag atggggtgga gtatgctcgt cttggtttga ttattatcga
    30781 tgagcagcac cgttttggtg tagggcaaag gcgtatttta cgggaaaaag gtgacaatcc
    30841 agatgtcctc atgatgacgg cgactcccat tccacggacg cttgccatca cagcctttgg
    30901 agatatggat gtttccatta tcgaccagat gccagcaggt cggaagccta ttgtgacgcg
    30961 ctggatcaaa catgagcaac tacctcaggt cttgacttgg ttagaggggg aaattcaaaa
    31021 aggttcccaa gcctatgtca tctctccttt gattgaagaa tcagaagctc tagatttgaa
    31081 aaatgccatt gccttatcag aggagttgac gactcatttt gcaggcaagg cagaggtggc
    31141 tcttctacat ggtaggatga agagtgacga aaaagaccag atcatgcagg atttcaagga
    31201 gagaaagacg gatattctgg tttcgacgac ggttattgag gttggggtca acgttcccaa
    31261 tgcgactgtc atgattatca tggatgccga tcgcttcggt ctcagtcaac ttcaccagct
    31321 tagaggtcgt gtcggtcggg gggacaagca gtcctacgct gttctcgttg ccaatcccaa
    31381 gacggattct gggaaagacc gcatgcgtat catgacagaa acgaccaatg gatttgtcct
    31441 tgcggaggaa gatttgaaaa tgcgtggttc tggtgagatt tttggaacca gacagtcagg
    31501 acttccagag ttccaagtgg ctgatattat cgaagatttt ccgattttag aagaagcaag
    31561 aaaggttgct agctacatta gttctataga agcttggcaa gaagatccag agtggcgcat
    31621 gattgccctt catctggaaa agaaagaaca tctggattaa gctttctcta aggaaaactt
    31681 aagctagttt ttaggtttgg ctcttatact aaagtcatca aaaagaaacg aggactctca
    31741 tatgacagta acgattaaag taaattacca aaccactttc caaaagaagg aagcaaaaaa
    31801 ctagtataaa cagaagagag agcgaaatgc tctttttcgt ttctaaaact actttcagcc
    31861 catcatccta aaagtaaaga atctaaattc actttctatt tatccttctt tcttgcattg
    31921 attacataga tatgctacag ttgtggtaac gattacaaaa taaaaggagc atgctatgaa
    31981 aaatccagct ttgctagaag aaattaagac ctatagagga agggatgagg ttccggaaga
    32041 ctttgatgct ttctgggatg gggaagtgaa aaatgtttcc acgcttccat cctaccactt
    32101 ggaggaaaga gatttccaca ttcctcaagt caagtgctat gagttaacat ttgaaggaag
    32161 caaggaagga aaggtctatg cacgcattgt tcttccaaag agtgaggaga aggttccact
    32221 aatcttccat tttcatggtt atatgggacg tggctgggac tgggccgaca tgctgggctt
    32281 caccgtagct ggttacggtg ttgtttccat ggatgtgcgg ggccagtcag gttactcaca
    32341 agacggcttg cgttctcctt taggaaatac cgtgaagggg catattatcc gtggtgctat
    32401 ggaaggtcgg gaccacctct tttataagga tgtttatctg gatatttacc agttggtcga
    32461 aattgttgct agtctgtctc aggttgatga gaagcgtctt tctagctatg gtgcctcaca
    32521 aggaggggct ctagctctag ttgcagcagc gctcaatcct cgaattcaga aaacagttgc
    32581 catttatccc ttcttgtcag acttcagacg ggtgattgag attggtaata ctagcgaggc
    32641 ttacgacgaa cttttccgtt atttcaagtt tcacgacccc ttccatgaaa cagaggagga
    32701 aatcatggcg acccttgcct atatcgatgt caaaaatctt gcccatcgta tccaaggtga
    32761 ggttaagatg attacgggct tggacgacga tgtttgctat cccattaccc agtttgcgat
    32821 ttataatcgt ctgacctgcg ataaaaccta tcgcatcatg cctgagtatg ctcacgaagc
    32881 catgaatgta tttgtcaatg accaagtcta caactggctc tgtggaagtg agattccttt
    32941 taaatatcta aaataaggag tcgactctaa gcacaaaatc ttaaaaatta caaacacgca
    33001 tagtatcagg ggattaaaaa aacttgatac tatgcgtttt atcatggaaa tatagtaaaa
    33061 tgaaacaaga ataggacaaa acgatcagga cagtcaaatc gatttctaac aatgttttag
    33121 aagcaaatgt gtactattct agtttcaatc tattatattt atagaatttt ttgttgctag
    33181 atttgtcaaa ttgcttaaaa taattttttt cagaaagcaa aagccgatac ctatcgagta
    33241 gggtagttct tgctatcgtc aggcttgtct gtaggtgtta atacttttca aaaatctctt
    33301 taaaccacgt cagcttcgcc ttgccgtata tatgttactg acttcgtcag ttctatctgc
    33361 cacctcaaaa cggtgttttg agctgacttt gtcagtctta tctacaacct caaaacagtg
    33421 ttttgagcat catgcggcta gcttcttagt ttgctctttg attttcattg agtataaaaa
    33481 cagatgagtt tctgttttct ttttatggac tataaatgtt cagctgaaac tactttcaag
    33541 gacattatta tataaaagaa ttttttgaaa ctaaaatcta ctatattaca ctatattgaa
    33601 agcgttttaa aaatgaggta taataaattt actaacgctt ataaaaagtg atagaatcta
    33661 tctttatgta tatttaaaga tagattgctg taaaaatagt agtagctatg cgaaataaca
    33721 gatagagaga agggattgaa gcttagaaaa ggggaataat atgatattta aggcattcaa
    33781 gacaaaaaag cagagaaaaa gacaagttga actacttttg acagtttttt tcgacagttt
    33841 tctgattgat ttatttcttc acttatttgg gattgtcccc tttaagctgg ataagattct
    33901 gattgtgagc ttgattatat ttcccattat ttctacaagt atttatgctt atgaaaagct
    33961 atttgaaaaa gtgttcgata aggattgagc aggaagtatg gtataaatag cataagctga
    34021 tgtccatcat ttgcttataa agagatattt tagtttaatt gcagcggtgt cctggtagat
    34081 aaactagatt ggcaggagtc tgattggaga aaggagaggg gaaaattggc accaatttga
    34141 gatagtttgt ttagttcatt tttgtcattt aaatgaactg tagtaaaaga aagttaataa
    34201 aagacaaact aagtgcattt tctggagtaa atgtcttatt tcagaaatcg ggatatagat
    34261 atagagagga tcagtatgaa tcggagtgtt caagaacgta agtgtcgtta tagcattagg
    34321 aaactatcgg taggagcggt ttctatgatt gtaggagcag tggtatttgg aacgtctcct
    34381 gttttagctc aagaaggggc aagtgagcaa cctctggcaa atgaaactca actttcgggg
    34441 gagagctcaa ccctaactga tacagaaaag agccagcctt cttcagagac tgaactttct
    34501 ggcaataagc aagaacaaga aaggaaagat aagcaagaag aaaaaattcc aagagattac
    34561 tatgcacgag atttggaaaa tgtcgaaaca gtgatagaaa aagaagatgt tgaaaccaat
    34621 gcttcaaatg gtcagagagt tgatttatca agtgaactag ataaactaaa gaaacttgaa
    34681 aacgcaacag ttcacatgga gtttaagcca gatgccaagg ctccagcatt ctataatctc
    34741 ttttctgtgt caagtgctac taaaaaagat gagtacttca ctatggcagt ttacaataat
    34801 actgctactc tagaggggcg tggttcggat gggaaacagt tttacaataa ttacaacgat
    34861 gcacccttaa aagttaaacc aggtcagtgg aattctgtga ctttcacagt tgaaaaaccg
    34921 acagcagaat tgccaaatgg tcgagttcgc ctgtatgtta atggtgtttt atctcgaaca
    34981 agtctgaaat ctggcaattt cattaaagat atgccagatg taacgcatgt gcaaatcgga
    35041 gcaaccaagc gtgccaacaa tacggtttgg gggtcaaatc tacagattcg gaatctcact
    35101 gtgtataatc gtgctttaac accagaagag gtacaaaaac gtagtcaact ttttaaacgc
    35161 tcagatttag aaaaaaaact acctgaagga gcggctttaa cagagaaaac ggacatattc
    35221 gaaagcgggc gtaacggtaa accaaataaa gatggaatca agagttatcg tattccagca
    35281 cttctcaaga cagataaagg aactttgatc gcaggtgcag atgaacgccg tctccattcg
    35341 agtgactggg gtgatatcgg tatggtcatc agacgtagtg aagataatgg taaaacttgg
    35401 ggtaaccgag taaccattac caacttacgt gacaatccaa aagcttctga cccatcgatc
    35461 ggttcaccag tgaatatcga tatggtgttg gttcaagatc ctgaaaccaa acgaatcttt
    35521 tctatctatg acatgttccc agaagggaag ggaatctttg gaatgtcttc acaaaaagaa
    35581 gaagcctaca aaaaaatcga tggaaaaacc tatcaaatcc tctatcgtga aggagaaaag
    35641 ggagcttata ccattcgaga aaatggtact gtctatacac cagatggtaa ggcgacagac
    35701 tatcgcgttg ttgtagatcc tgttaaacca gcctatagcg acaagggtga tctatacaag
    35761 ggtaaccaat tactaggcaa tatctacttc acaacaaaca aaacttctcc atttagaatt
    35821 gccaaggata gctatctatg gatgtcctac agtgatgacg acgggaagac atggtcagcg
    35881 cctcaagata ttactccgat ggtcaaagcc gattggatga aattcttggg tgtaggtcct
    35941 ggaacaggaa ttgtacttcg gaatgggcct cacaagggac ggattttgat accggtttat
    36001 acgactaata atgtatctca cttaaatggc tcgcaatctt ctcgtgtcat ctattcagat
    36061 gatcatggaa aaacttggca tgctggagaa gcggtcaacg ataaccgtca ggtagacggt
    36121 caaaagatcc actcttctac gatgaacaat agacgtgcgc aaaatacaga atcaacggtg
    36181 gtacaactaa acaatggaga tgttaaactc tttatgcgtg gtttgactgg agatcttcag
    36241 gttgctacaa gtaaagacgg aggagtgact tgggagaagg atatcaaacg ttatccacag
    36301 gttaaagatg tctatgttca aatgtctgct atccatacga tgcataatgg aaaagaatac
    36361 attatcctca gcaatgcagg tggaccgaat cgtgaaaatg ggatggtcca cttggcacgt
    36421 gtcgaagaaa atggtgagtt gacttggctc aaacacaatc caattcaaaa aggagagttt
    36481 gcctataatt cgctccaaga attaggaaat ggggagtatg gcatcttgta tgaacatact
    36541 gaaaaaggac aaaatgccta taccctatca tttagaaaat ttaattggga atttttgagc
    36601 aaagatctga tttctcctac cgaagcgaaa gtgaagcgaa ctagagagat gggcaaagga
    36661 gagatgggca aaggagttat tggcttggag tttgactcag aagtattggt caacaaggct
    36721 ccaacccttc aattggcaaa tggtaaaaca gcgactttcc taacccagta tgatagcaaa
    36781 accttgttgt ttgcagtaga taaggaagat atcggacagg aaattattgg tatagctaaa
    36841 ggaagcatcg aaagtatgca taatcttcct gtaaatctag caggtgccag agttcctggc
    36901 ggagtaaatg gtagcaaagc agcggtgcat gaagttccag aatttacagg gggagttaat
    36961 ggtacagagc cagctgttca tgaaatcgca gagtataagg gatctgattc gcttgtaact
    37021 cttactacaa aagaagatta tacttacaaa gctcctcttg ctcagcaggc acttcctgaa
    37081 acaggaaaca aggagagtga cctcctagct tcactaggac taacagcttt cttccttggt
    37141 ctgtttacgc tagggaaaaa gagagaacaa taagagaaga attctaaaca tttgattttg
    37201 taaaaataga aggagatagc aggttttcaa gcctgctatc tttttttgat gacattcagg
    37261 ctgatacgaa atcataagag gtctgaaact actttcagag tagtctgttc tataaaatat
    37321 agtagattga aataagatgt gaacaactct atcaggaaag tcaaattaat ttatagaaaa
    37381 attttagcag tcaaggtgta ctgttataga ttcaatatat tatgtgacta ttaaccttct
    37441 cttctcctaa aattgacttt cttgttttct tatcttgtcc actcgaaaca agtattgtaa
    37501 gaatttgatt atttttgaaa gtacttttaa tatacttgat atagttaaaa aagatttgaa
    37561 actaaattcc aaattagaaa aagacttgaa atactaaaaa aaaaaaaagt atactctaat
    37621 tgaaaacggt aacaaaacta atttagagaa tgaaatatag agtatttctc tcttaaaagt
    37681 ttttggtgaa acgagatgta gaaaggagat ttagccaaag agtctattag tgctagaata
    37741 atagattaga attattttag aaaaacgaag tgagcagctt ataaattcaa gtccccaaat
    37801 agattcatac tagtatcttt tgcaaaaaat aaagggcgac ttccttcatg aatatcaatt
    37861 tcatctataa ggaaggtagc taattgaact aacttattta ttctgtttgt cgctagaaaa
    37921 atcagacctc cttgtgaaga ttgaggagat actgaatgaa aatcaaagaa gaaactagca
    37981 agctagtagc agattgccca aaacaccgcc ttgaggttgt agataagact gacctatata
    38041 atccaaggtg aagcgactgt ggtttgaaga gattttcaaa gagtataggc tagagagtag
    38101 tgtttttatg tccttctagt agaaaatgct agacagaaga atggggaact tggataggaa
    38161 aaatagattg agaaaggagg ttagaagaga tgattattac aaaaattagc catttaggaa
    38221 cttatgtggg agtaaatcca cattttgcaa cattaataga ttttctagaa aaaacaggac
    38281 tagaaaattt aacagaaggt tcgattgcta tcgatggtaa tcgattgttt gggaattgct
    38341 ttacttatct agcagatggt caagcagggg ctttctttga aacacaccaa aaatatttgg
    38401 atattcattt agttttggaa aacgaagaag ccatggctgt tacatcgccg gaaaatgtaa
    38461 gcgttaccca agaatatgat gaagagaaag atattgaatt atacacaggg aaagtggaac
    38521 agttggttca gttgagagct ggcgaatgcc tcatcacttt tccagaagat ttacatcaac
    38581 ccaaggttcg tataaatgat gaacctgtga aaaaagttgt ctttaaagtt gcgatttctt
    38641 aatgtagaaa gagaagaacg atgaaaaaaa tgagaaagtt tttatgtcta gctggaattg
    38701 cgctagcggc tgttgccttg gtagcttgtt caggaaaaaa agaagctaca actagtactg
    38761 aaccaccaac agaattatct ggtgagatta caatgtggca ctcctttact caaggacccc
    38821 gtttagaaag tattcaaaaa tcagcagatg ctttcatgca aaagcatcca aaaacgaaaa
    38881 tcaagattga aacattttct tggaatgact tctatactaa atggactaca ggtttagcaa
    38941 atggaaatgt gccagatatc agtacagctc ttcctaacca agtaatggaa atggtcaact
    39001 cagatgcttt ggttccgcta aatgattcta tcaagcgtat tggacaagat aaatttaacg
    39061 aaactgcctt aaatgaagca aaaatcggag atgattacta ctctgttcct ctttattcac
    39121 atgcacaagt catgtgggtt agaacagatt tgttaaaaga acataatatt gaggttccta
    39181 aaacttggga tcaactctat gaagcttcta aaaaattgaa agaagctgga gtttatggct
    39241 tgtctgttcc gtttggaaca aatgacttaa tggcaacacg tttcttgaac ttctacgtac
    39301 gtagtggtgg aggaagcctc ttaacaaaag atcttaaagc agacttgaca agccaacttg
    39361 ctcaagatgg tattaaatac tgggttaaat tgtataaaga aatctcacct caagattctt
    39421 tgaactttaa tgtccttcaa caagctacct tgttctatca aggaaaaaca gcatttgact
    39481 ttaactctgg cttccatatc ggaggaatta atgccaacag tcctcaattg attgattcga
    39541 ttgatgctta tcctattcca aaaatcaaag agtctgataa agaccaagga attgaaacct
    39601 caaacattcc aatggttgtt tggaaaaatt caaaacatcc agaagttgct aaagcattct
    39661 tagaagcact ttataatgaa gaagactacg ttaaattcct tgattcaact ccagtaggta
    39721 tgttgccaac tattaagggg attagcgatt ctgcagccta taaagaaaat gaaactcgta
    39781 agaagtttaa acatgctgaa gaagtaatta ctgaagctgt taaaaaaggt actgctattg
    39841 gttatgaaaa tggaccaagt gtacaagctg gtatgttgac taaccaacac attattgaac
    39901 aaatgttcca agatatcatt acaaatggaa cagatcctat gaaagcagca aaagaagcag
    39961 aaaaacaatt aaacgattta tttgaggctg ttcagtagat gtaaaagact agaaaatagg
    40021 tgggctagtg agctgaaaag ctctagccca atcttgtaaa agaagggaga aggagaatgg
    40081 ttaaagaacg taatttaact cgctggatat ttgttttgcc agctatgatt atcgtaggat
    40141 tactctttgt ttatccgttt ttctcgagta ttttttatag ctttaccaat aagcatttga
    40201 ttatgcctaa ttataaattt gttggtttgg ctaactataa agctgtgcta tcagatccca
    40261 acttctttaa tgcgttcttt aattcaatta agtggaccgt tttctcatta gttggtcaag
    40321 ttttagtagg gtttgtattg gctttagctc ttcacagagt acgccacttc aagaaattat
    40381 ataggacctt attgattgtt ccttgggcat ttcctaccat cgttattgcc ttttcttggc
    40441 agtggattct aaacggggtt tatggctact tacctaatct aatcgtaaaa ttaggtttaa
    40501 tggaacatac acctgcattt ttgacagata gtacatgggc attcctatgt ttggtgttta
    40561 tcaacatttg gtttggagca ccaatgatta tggttaatgt gctttcagct ttgcaaacag
    40621 taccagaaga acaatttgag gctgctaaga tagatggtgc ttcaagttgg caggtgttca
    40681 agtttatcgt ctttccacat attaaagtgg ttgtaggact tctagttgtt ttgagaactg
    40741 tatggatctt taataacttt gacattatct acctcattac tggtggtgga ccagccaatg
    40801 ctacaacgac gcttccaatt tttgcttaca acctgggctg gggaactaaa ttgttgggtc
    40861 gtgcttcagc agttacagta ttgctcttta tcttcttggt ggcgatttgc tttatctact
    40921 ttgctatcat cagtaagtgg gaaaaggagg gtagaaaata atgaagaaga aatccagtat
    40981 ttatttagat attctctcac atgtactttt agttggtgcg accatcgttg caattttccc
    41041 attggtatgg attatcatat cttctgtcaa agggaaaggg gaattaactc agtatccaac
    41101 acgattttgg cctgaacagt ttacattaga ttatttcact catgttatca acgatttgca
    41161 cttcattgat aacattcgaa acagtttaat cattgccttg gctacaaccc tcattgcgat
    41221 tattatttct gctatggcag cctatggtat tgttcgattc tttcctaaat tgggagcaat
    41281 catgtcgaga ctactcgtca ttacctacat tttcccacca attttgttag caattcccta
    41341 ttcaattgcc attgctaaag ttgggttaac aaatagttta tttggcttga tgatggttta
    41401 tctatctttt agtgttccat atgcagtttg gctcttagtt ggatttttcc aaacagttcc
    41461 aattggaatt gaagaagcgg ctagaattga tggtgcaaat aaatttgtta cgttttataa
    41521 agttgtgcta ccgattgtag caccaggtat tgtagcaaca gctatttata catttatcaa
    41581 tgcttggaat gaattcctgt atgccttgat tttgattaac aatacaggaa agatgacagt
    41641 agcagtagcc cttcgttcac ttaatggttc agaaatacta gactggggag atatgatggc
    41701 agcgtctgtt attgtagttc ttccatcaat tattttcttc tctatcatcc aaaataagat
    41761 tgcaagtgga ttatcagaag gatctgtgaa gtagacgaaa gaaggaaaaa aatgaataaa
    41821 agaggtcttt attcaaaact aggaatttct gttgtaggca ttagtctttt aatgggagtc
    41881 cccactttga ttcatgcgaa tgaattaaac tatggtcaac tgtccatatc tcctattttt
    41941 caaggaggct catatcaact gaacaataag agtatagata tcagcccttt gttattagat
    42001 aaattgtctg gagagagtca gacagtagta atgaaattta aagcagatga accaaactct
    42061 cttcaagctt tgtttggcct atctaatagt aaagcaggct ttaaaaataa ttacttttca
    42121 attttcatga gagattctgg tgagataggt gtagaaataa gagacgccca aaagggaata
    42181 aattatttat tttccagacc agcttcatta tggggaaaac ataaaggaca ggcagttgaa
    42241 aatacactag tatttgtatc tgattctaaa gataaaacat acacaatgta tgttaatgga
    42301 atagaagtgt tctctgaaac agttgataca tttttgccaa tttcaaatat aaatggtata
    42361 gataaggcaa cactaggagc tgttaatcgt gaaggcaagg aacattacct cgcaaaaaga
    42421 agtattgatg aaatcagtct atttaacaaa gcaattagtg atcaggaagt ttcaaatatt
    42481 cccttgtcaa atccatttca gttaattttc caatcaggag attctactca agctaactat
    42541 tttagaatac cgacactata tacattaagt agtggaagag ttctatcaag tattgatgca
    42601 cgttatggtg ggactcatga ttctaaaagt aagattaata ttgccacttc ttatagtgat
    42661 gataatggga aaacgtggag tgagccaatt tttgctatga agtttaatga ctatgaggag
    42721 cagttagttt actggccacg agataataaa ttaaagaata gtcaaattag tggaagtgct
    42781 tcattcatag attcatccat tgttgaagat aaaaaatctg ggaaaacgat attactagct
    42841 gatgttatgc ctgcgggtat tggaaataat aatgcaaata aagccgactc aggttttaaa
    42901 gaaataaatg gtcattatta tttaaaacta aagaagaatg gagataacga tttccgttat
    42961 acagttagag aaaatggtgt cgtttatgat gaaacaacta ataaacctac aaattatact
    43021 ataaatgata agtatgaagt tttggaggga ggaaagtctt taacagtcga acaatattcg
    43081 gttgattttg atagtggctc tttaagagaa aggcataatg gaaaacaggt tcctatgaat
    43141 gttttctaca aagattcgtt atttaaagtg actcctacta attatatagc aatgacaact
    43201 agtcagaata gagaagagag ttgggaacaa tttaagttgt tgcctccgtt cttaggagaa
    43261 aaacataatg gaacttactt gtgtcctgga caaggtttag cattaaaatc aagtaacaga
    43321 ttgatttttg caacatatac tagtggagaa ctaacctatc tcatttctga tgatagtggt
    43381 caaacatgga agaaatcctc agcttcaatt ccgtttaaaa atgcaacagc agaagcacaa
    43441 atggttgaac tgagagatgg tgtgattaga acattcttta gaaccactac aggtaagata
    43501 gcttatatga ctagtagaga ttctggagaa acatggtcgg aagtttcgta tattgatgga
    43561 atccaacaaa cttcatatgg cacacaagta tctgcaatta aatactctca attaattgat
    43621 ggaaaagaag cagtcatttt gagtacacca aattctagaa gtggccgtaa gggaggtcaa
    43681 ttagttgtcg gtttagtcaa taaagaagat gatagtattg attggaaata ccactatgat
    43741 attgatttgc cttcgtatgg ttatgcctat tctgcgatta cagaattgcc aaatcatcac
    43801 ataggtgtac tgtttgaaaa atatgattcg tggtcgagaa atgaattgca tttaagcaat
    43861 gtagttcagt atatagattt ggaaattaat gatttaacaa aataaaggag aaaaacatgg
    43921 ttaaatacgg tgttgttgga gcagggtatt ttggagctga attggctcgc tacatgcaaa
    43981 agaatgatgg agcagagatt actcttctct atgatccaga taatgcagag gcgattgcag
    44041 aagaattggg agcaaaagta gcaagttcct tagatgagtt ggtttctagc gatgaagtag
    44101 attgtgttat cgtcgcaact ccaaataatc ttcataagga accggttatt aaggctgcac
    44161 agcatggtaa aaatgttttc tgtgaaaaac caattgcgct ttcttatcaa gattgtcgcg
    44221 agatggtaga tgcgtgtaaa gaaaacaatg taacctttat ggcaggacat attatgaatt
    44281 tctttaatgg tgttcatcat gcaaaagaac tcattaatca aggagttatc ggagacgttc
    44341 tatattgtca tacagctcgt aatggttggg aagaacaaca accgtcagtg tcatggaaaa
    44401 aaattcgtga aaaatcaggt ggtcacttgt atcaccacat ccatgaattg gattgcgttc
    44461 aattccttat ggggggcatg cctgaaactg taaccatgac aggtggaaat gtggcccatg
    44521 aaggtgaaca tttcggtgat gaagatgata tgatttttgt caatatggaa ttttctaata
    44581 agcgttttgc cttgttagaa tggggttcag cttatcgttg gggtgaacat tatgtcttaa
    44641 tccaaggaag caaaggtgcc atccgcttag acttattcaa ctgtaaagga actcttaagc
    44701 tagatgggca agaaagctat ttcttgattc acgaatcgca agaagaagat gatgatcgga
    44761 ctcgtatcta tcatagtaca gagatggatg gagcaattgc ttatggtaaa ccaggtaaac
    44821 gtactccatt atggctatca tctgtcattg ataaagaaat gcgctatctg catgagatta
    44881 tggaaggagc tccagtatca gaagaatttg caaaactttt gacaggtgaa gctgccctag
    44941 aagcaattgc tactgcagat gcttgtaccc agtctatgtt tgaagatcgc aaagtaaaat
    45001 tgtcagaaat tgtaaaataa attttggtat tctcctattt ataggtcgac ttgctcctct
    45061 gaaagtactt ttagaggagc tgtttgactt tgctagtttt tgaaactgaa atctattata
    45121 ctacaaacta ttgaaagcgt tttaatttta aggtataata atctcataga aataaagaaa
    45181 aggaggaaag aggatgccac agattagcaa agaagccttg attgagcaaa tcaaagatgg
    45241 aatcatcgtt tcttgtcagg ctcttcctca tgaaccgctt tatacagaag cgggaggggt
    45301 gattcccttg ctggtcaaag cggctgagca aggtggagca gtcggtatcc gagcaaacag
    45361 tgttcgcgat atcaaggaaa ttaaggaagt cactaaactt ccaatcattg ggattatcaa
    45421 acgtgattat ccacctcagg aacccttcat cacggctact atgaaagaag ttgatgaatt
    45481 ggcagaactg gacatcgagg tgattgctct ggattgtacc aagcgtgaac gctacgatgg
    45541 tttggaaatt caagagttca ttcgtcaggt taaggagaaa tatcctaatc agcttttgat
    45601 ggctgatact agtatcttcg aagaagggct agcagctgta gaagcaggaa ttgactttgt
    45661 cggaacaacc ttatcaggct acacatccta cagtccaaaa gtagacggtc cagattttga
    45721 attgattaag aaactctgtg atgccggtgt agatgtcatt gcagaaggaa aaattcatac
    45781 accagaacaa gccaaacaaa tccttgaata tggagtgcga ggcatcgttg ttggtggcgc
    45841 cattactaga ccaaaagaga ttacagaacg cttcgttgct agtcttaaat aagatgtgag
    45901 ggggagtttt atgtttaaag ttttacaaaa agttggaaaa gcttttatgt tacctatagc
    45961 tatacttcct gcagcaggtc tacttttggg gattggtggt gcactttcaa acccaaccac
    46021 gatagcaact tatccaatac tagacaatag tatttttcaa tcaatattcc aagtaatgag
    46081 ctctgcagga gaggttgtat tcagtaattt gtcactactt ctctgtgtgg gattatgtat
    46141 tggcttagcg aaacgagata aaggaaccgc tgcgttagca ggagtaactg gttacttagt
    46201 tatgactgca acgatcaaag ctttagtaaa actttttatg gcagaaggat ctgcaattga
    46261 tactggagtt attggagcat tagttgtcgg aatagttgcc gtatatttgc acaaccgata
    46321 taacaatatt caattacctt ccgctttagg attctttgga ggttcacgct tcgttcctat
    46381 tgttacatcg ttctcttcta tcttgattgg ctttgtcttc tttgttattt ggccaccttt
    46441 ccaacaactt cttgtttcta caggtggata tatttctcag gcgggtccaa ttggaacttt
    46501 tctatatgga tttttaatga gactttctgg agcagtaggc ttacatcata taatttaccc
    46561 tatgttttgg tatactgaac ttggtggtgt tgaaactgtt gcaggacaaa cagtggttgg
    46621 agctcaaaaa atattttttg ctcaattagc cgatttggcc cattctggat tatttacaga
    46681 aggaacaagg ttttttgcag gtcgtttctc aacaatgatg ttcggtttac cggctgcctg
    46741 tttagcgatg taccatagtg ttcctaaaaa tcgtcgtaaa aaatacgcgg gtttgttttt
    46801 gggagttgct ttaacatctt ttattaccgg tattacagaa ccaattgaat ttatgtttct
    46861 attcgttagt ccggttctat atgttgttca cgcattcctt gatggtgtta gcttctttat
    46921 tgcagacgtc ttaaatattt caataggaaa cacattttca ggaggtgtaa tcgatttcac
    46981 tttatttgga attttgcagg ggaacgctaa gacgaattgg gttcttcaga ttccatttgg
    47041 acttatttgg agtgtttt
//
LOCUS       DAVBIC010000008        46211 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.008, whole genome shotgun sequence.
ACCESSION   DAVBIC010000008 DAVBIC010000000
VERSION     DAVBIC010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 46211)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46211)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46211
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.008"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            <1..128
                     /locus_tag="VQ664_000441"
     CDS             <1..128
                     /locus_tag="VQ664_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HET2788669.1"
                     /translation="FQSLNQLEQAIVDYIDYYNNKRIKVKLKGLSPVQYRTKSFG"
     gene            complement(257..460)
                     /locus_tag="VQ664_000442"
     CDS             complement(257..460)
                     /locus_tag="VQ664_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2788670.1"
                     /translation="MIKLYSPYAFLSKYLGAILLSFFCYYAKEIGCNNLTLSVWNDNE
                     GALRFYQRQGMKPQETTMEMIID"
     gene            complement(453..1535)
                     /locus_tag="VQ664_000443"
     CDS             complement(453..1535)
                     /locus_tag="VQ664_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HET2788671.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTVFETAEFDNLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(1661..2443)
                     /locus_tag="VQ664_000444"
     CDS             complement(1661..2443)
                     /locus_tag="VQ664_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HET2788672.1"
                     /translation="MVYTSLSSKDSNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(2443..3786)
                     /locus_tag="VQ664_000445"
     CDS             complement(2443..3786)
                     /locus_tag="VQ664_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HET2788673.1"
                     /translation="MNLKTTLGLLAGRSSHFVLSRLGRGSTLPGKVALQFDKDILQSL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILDAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKECTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            complement(3885..5201)
                     /locus_tag="VQ664_000446"
     CDS             complement(3885..5201)
                     /locus_tag="VQ664_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HET2788674.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYATVAGTGVDIFDAEAHFLS
                     NKVIEIQAGDEKKELTAETIVINTGAVSNVLPIPGLATSKNIFDSTGIQSLDKLPEKL
                     GILGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYMEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            5394..6615
                     /locus_tag="VQ664_000447"
                     /pseudo
     CDS             5394..6615
                     /locus_tag="VQ664_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
     gene            6814..8388
                     /locus_tag="VQ664_000448"
     CDS             6814..8388
                     /locus_tag="VQ664_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET2788675.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRTEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQDIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVAPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LSEKQTGFVIRNKGDK"
     gene            8652..9440
                     /gene="codY"
                     /locus_tag="VQ664_000449"
     CDS             8652..9440
                     /gene="codY"
                     /locus_tag="VQ664_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HET2788676.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            9440..10015
                     /locus_tag="VQ664_000450"
     CDS             9440..10015
                     /locus_tag="VQ664_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HET2788677.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDFFHPESKLFPPHNLIGTSGRNLYGDLGIFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            10097..10182
                     /locus_tag="VQ664_000451"
     tRNA            10097..10182
                     /locus_tag="VQ664_000451"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10131..10133,aa:Leu,seq:aag)
     gene            10465..11595
                     /gene="ugpC"
                     /locus_tag="VQ664_000452"
     CDS             10465..11595
                     /gene="ugpC"
                     /locus_tag="VQ664_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HET2788678.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFINVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            12096..12854
                     /locus_tag="VQ664_000453"
     CDS             12096..12854
                     /locus_tag="VQ664_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HET2788679.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGLSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKVLTGEMTLMKLSGMIYDEGWLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            12941..13453
                     /locus_tag="VQ664_000454"
     CDS             12941..13453
                     /locus_tag="VQ664_000454"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HET2788680.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            13635..14579
                     /locus_tag="VQ664_000455"
     CDS             13635..14579
                     /locus_tag="VQ664_000455"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HET2788681.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYGYL"
     gene            14588..15265
                     /locus_tag="VQ664_000456"
     CDS             14588..15265
                     /locus_tag="VQ664_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HET2788682.1"
                     /translation="MTYLDAFKSGTLVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEMSPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELLFDASLALERL
                     DDLFGAVRSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFRN
                     AMDLWKD"
     gene            15363..16121
                     /locus_tag="VQ664_000457"
     CDS             15363..16121
                     /locus_tag="VQ664_000457"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HET2788683.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            16159..17664
                     /gene="lytC"
                     /locus_tag="VQ664_000458"
     CDS             16159..17664
                     /gene="lytC"
                     /locus_tag="VQ664_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
                     /protein_id="HET2788684.1"
                     /translation="MSVTFFIGEERLKTKIGLASICLLGLATSHVAANETEVAKTSQD
                     TTTASSSSEQNQSSNKTQTSTEVQTNAAAHWDGDYYVKDDGSKAQSEWIFDNYYKAWF
                     YINSDGRYSQNEWHGNYYLKSGGYMAQNEWIYDSNYKSWFYLKSDGAYAHQEWQLIGN
                     KWYYFKKWGYMAKSQWQGSYFLNGQGAMMQNEWLYDPAYSAYFYLKSDGTYANQEWQK
                     VGGKWYYFKKWGYMARNEWQGNYYLTGSGAMATDEVIMDGARYIFAASGELKEKKDLN
                     VGWVHRDGKRYFFNNREEQVGTEHAKKIIDISEHNGRINDWKKVIDENEVDGVIVRLG
                     YSGKEDKELAHNIKELNRLGIPYGVYLYTYAENETDAESDAKQTIELIKKYNMNLSYP
                     IYYDVENWEYVNKSKRAPSDTGTWVKIINKYMDTMKQAGYQNVYVYSYRSLLQTRLKH
                     PDILKHVNWVAAYTNALEWENPHYSGKKGWQYTSSEYMKGIQGRVDVSVWY"
     gene            18160..18678
                     /locus_tag="VQ664_000459"
     CDS             18160..18678
                     /locus_tag="VQ664_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HET2788685.1"
                     /translation="MVELKKEAVKDVTSLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGQLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEAGEYRNVEESLERVLVIYRYLSELFQKGLDVTDEEGDDVTNGIFAGAKTETDKTIW
                     MLAAELGQAPGL"
     gene            18808..19314
                     /locus_tag="VQ664_000460"
     CDS             18808..19314
                     /locus_tag="VQ664_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HET2788686.1"
                     /translation="MTKKIVAIWAQDEEGVIGKENRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQAQEKNLYIIGG
                     KQIFQAFEPYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEV"
     gene            19516..20748
                     /gene="clpX"
                     /locus_tag="VQ664_000461"
     CDS             19516..20748
                     /gene="clpX"
                     /locus_tag="VQ664_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HET2788687.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            20757..21344
                     /locus_tag="VQ664_000462"
     CDS             20757..21344
                     /locus_tag="VQ664_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HET2788688.1"
                     /translation="MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            21355..21735
                     /locus_tag="VQ664_000463"
     CDS             21355..21735
                     /locus_tag="VQ664_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HET2788689.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            21787..22677
                     /gene="rapZ"
                     /locus_tag="VQ664_000464"
     CDS             21787..22677
                     /gene="rapZ"
                     /locus_tag="VQ664_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HET2788690.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLAQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            22674..23651
                     /locus_tag="VQ664_000465"
     CDS             22674..23651
                     /locus_tag="VQ664_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HET2788691.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVAGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            23648..24559
                     /gene="whiA"
                     /locus_tag="VQ664_000466"
     CDS             23648..24559
                     /gene="whiA"
                     /locus_tag="VQ664_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HET2788692.1"
                     /translation="MSFTVAVKEEILGQHHLSRHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(24593..25561)
                     /locus_tag="VQ664_000467"
     CDS             complement(24593..25561)
                     /locus_tag="VQ664_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HET2788693.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEEFAITTS
                     KGSHLTKTVIIAMGGGAFKPRPLELEGVEGYENIHYHVSNIQQYAGKKVTILGGGDSA
                     VDWTLAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFAPSQLLGNGKTLDKL
                     EITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYA
                     IGDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            25697..26554
                     /locus_tag="VQ664_000468"
     CDS             25697..26554
                     /locus_tag="VQ664_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HET2788694.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYISTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            26541..27320
                     /locus_tag="VQ664_000469"
     CDS             26541..27320
                     /locus_tag="VQ664_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HET2788695.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            27344..28696
                     /locus_tag="VQ664_000470"
     CDS             27344..28696
                     /locus_tag="VQ664_000470"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HET2788696.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAIQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID
                     "
     gene            28770..29144
                     /locus_tag="VQ664_000471"
     CDS             28770..29144
                     /locus_tag="VQ664_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HET2788697.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPSELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            29146..29994
                     /locus_tag="VQ664_000472"
     CDS             29146..29994
                     /locus_tag="VQ664_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HET2788698.1"
                     /translation="MKLAVFTDSSAYLSEETLQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYIPVI"
     gene            30271..31038
                     /locus_tag="VQ664_000473"
     CDS             30271..31038
                     /locus_tag="VQ664_000473"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HET2788699.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLTDPDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLAGFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEVRESIQQGAADEEELIAGARGADFDDMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            31050..32234
                     /locus_tag="VQ664_000474"
     CDS             31050..32234
                     /locus_tag="VQ664_000474"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HET2788700.1"
                     /translation="MPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHSPIHDVDIA
                     TSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSAVSFVR
                     SLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDALRIMR
                     GFRFQASLGFALEPETFKAMKTLTPLLEKISVERTFVEFDKLLLAPFWRRGLASMIES
                     QAYDYLPDMASSQDKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKSWKTSR
                     QFAKQVQDLLIILALRENGELSKRDCYRFDIDLLLQAENLRQAQGKEVNPQAITEKYQ
                     SLTIHDKKEIQINGDILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIHAYLRE
                     KK"
     gene            32231..34102
                     /locus_tag="VQ664_000475"
     CDS             32231..34102
                     /locus_tag="VQ664_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET2788701.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTVLSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELDRAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELAWMRRQPQAR
                     ATKQQARINRFHDLKKEVSGSSAETDLTMNFETSRIGKKVIEFQAVSFAYENKPILQD
                     FNLLVQAKDRIGIVGDNGVGKSTLLNLIAGSLEPTKGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDSKIRPFFGHYTDYLDEKAFETDMANQVQKVEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIETLEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(34245..35429)
                     /gene="mntE"
                     /locus_tag="VQ664_000476"
     CDS             complement(34245..35429)
                     /gene="mntE"
                     /locus_tag="VQ664_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HET2788702.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLAAGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLEERF
                     GVFDTDVHIEPAPISEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            35733..38429
                     /locus_tag="VQ664_000477"
     CDS             35733..38429
                     /locus_tag="VQ664_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HET2788703.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLAEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LIEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVVLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEGHVLTGAELNELSDEEFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            38442..39233
                     /gene="yghU"
                     /locus_tag="VQ664_000478"
     CDS             38442..39233
                     /gene="yghU"
                     /locus_tag="VQ664_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HET2788704.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRPTAGARFEQNLPKGEQAFQ
                     LYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTENVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QGNLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            39349..39759
                     /locus_tag="VQ664_000479"
     CDS             39349..39759
                     /locus_tag="VQ664_000479"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HET2788705.1"
                     /translation="MEKKIVKDILFLSQVSHPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGMQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETIRL
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            39771..41366
                     /locus_tag="VQ664_000480"
     CDS             39771..41366
                     /locus_tag="VQ664_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2788706.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPKSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTN
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESIKGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKVQ"
     gene            41533..41697
                     /locus_tag="VQ664_000481"
     CDS             41533..41697
                     /locus_tag="VQ664_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HET2788707.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGTALV
                     LVAVWLGWPK"
     gene            41776..42504
                     /gene="yaaA"
                     /locus_tag="VQ664_000482"
     CDS             41776..42504
                     /gene="yaaA"
                     /locus_tag="VQ664_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HET2788708.1"
                     /translation="MKILIPTAKEMNTDLPSIEAIPLKPESQTVLDALALYSASQLES
                     FYKVSAEKAAEEFQNIQALKRQTAQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPALSPMAPHRLDFLMKLKVAGKTLKSHWKAVYDEALKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(42555..44039)
                     /locus_tag="VQ664_000483"
     CDS             complement(42555..44039)
                     /locus_tag="VQ664_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003096885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET2788709.1"
                     /translation="MRNLLSTKVQRQLRLMETLIQNRNWMKLHELAEKLGCTERILKS
                     DLNELRIAFPSINIQSSVNGIMIDLEVNTSVEDIYQYFLANSQSFQLLEYMFFNEGLP
                     IYRTIENLYFSSANLYRLGRNITKVLSSQFQIELSFTPSEIRGNEIDIRYFFAQYFSE
                     RYYFLDWPFPDLPEEDLTEFADFFYKITNYPMRFSIYRMYKLMIAISIHRVKNGHFID
                     LPNHFYKEYYPLLKSIPNFQETLAYFSKHFGLEMTPDTIAQIFISFLQNDIFLDPQEF
                     FNSLEDNSQARYSYQLLSQILERLSKQYKITFTNHDELIWHLHNTAFFERQEIFSTPI
                     LFEQKALTIKKFEGYFPDFMGSARQELAQYRQAIGQHDHPEQLEHLMYTILTHAENLS
                     TQLLENRPPIKVLIISNFDHAISLTFVDMLSYYCNNRFTFDIWDELKTSPEILNQTDY
                     DIIVSNFYISGITKKFICRNHLSIMNLVNHLNTLSNEIHLSNTL"
     gene            44255..>46211
                     /locus_tag="VQ664_000484"
     CDS             44255..>46211
                     /locus_tag="VQ664_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HET2788710.1"
                     /translation="MKHSHKKSFDWYSMQQRYSIRKYYFGAVSVLLGTALVLGAAASV
                     QTVQAEENKQETTNSISVGRGEAATKPAEVSASNKEKTYAAPTVANPVETTPVKTGEV
                     TKPAEKVEEAKDKKEEVTHQDAIDKSKLLTALSRAKKLESKLYTEASAANLQTSIQAG
                     QSLLGKADASEAELSAAESSIQSSIIGLELRSNSNKGTVSETPVAKKANIVEAKEETN
                     PAATTDRSAVDSAVLPTSTAAKVETTSAPASINEILKPGLSLSDARQNPAIRKEDVDR
                     GYSGFRAAPAPTNQPVTNLGNNTVFTDISRGSHTFRGNGNSRRGNPIHFDVTTTRVRN
                     RVDFSIRYSGPGEFVNNNFILDKGNGFGEPSRATVSTPKLRDQVKNISKGGNFVSHSG
                     YSLEAAVETSTNQTIKFSLPIANPNGDLSVRLRPVTFNVGQGESGSATSNDPYSNSNY
                     YFREKPLLLDANPNGGTNNKTVSEDIDFQTVYLPTSKLPEGQTRLVREGEKGQRQIIY
                     KVHQLGNETILGLPISNSVIKEVKPRIMQIGVAKDLIDTVKPRVDQNKVGDTNNLTFY
                     LDNDGNGVYTEGVDELVQKIAIKDGAKGEKGARGERGLTGAQGAKGEKGDRGERGLTG
                     AQGAKGEKGDRGERGLTGAQGAKGEKGD"
BASE COUNT        13768 a         8553 c        10458 g        13432 t
ORIGIN      
        1 cgtttcagtc gcttaatcaa ttggaacaag ctattgtaga ctatattgat tactacaaca
       61 ataaacgaat taaggtaaaa ctaaaaggac ttagtcctgt gcaatacaga actaaatcct
      121 tcggataaat taattgtcta actgtttggg ggcagtacat attcaacacc tgatactatg
      181 cgttttattg tgggaagatt ttcctcattt tctagtgaaa ttgaactttt tctaacatct
      241 tttgatagat gacttcttaa tcaattatca tttccattgt tgtttcttgg ggtttcatcc
      301 cttgtctttg ataaaagcgg agagcaccct cgttatcatt ccagacactt agggttagat
      361 tattgcagcc aatttcttta gcataatagc agaaaaatga caataaaata gcccctagat
      421 attttgaaag gaaagcatag gggctatata gtttaatcaa aataaagcaa atctttgctg
      481 gtgcttgtaa agaggtcgaa gccatccttg gtaacaacac cgcagtcttc aatacgaaca
      541 ccgactttac cagggatata gatacctggt tcaacagaga agcacatgcc ttcttcgatg
      601 accatgtcgt ttccttccat gatagatggg aattcatgga catccatacc gataccatgc
      661 ccgagacggt ggttgaagta ctcaccataa ccagcttttt cgatgacctc acgggcagcg
      721 cggtccactt catgagcagt cacacctggc ttgataaagt caagagcagc ttgttgggct
      781 tcaagagtca agttgtaaat atctttcttg aattggtctg gtttgccgac agcgactgta
      841 cgagtcatat ctgacgcata gccattgacc agaacaccca ggtcaaagag gagaagagca
      901 tcattttcaa ccttattagc tgctggaatg ccgtgtggat tcgcagcatt atcaccagtc
      961 aagaccatgg tatcaaagct catttcataa ccttcacgtt tcatggcaaa gtcgatttgt
     1021 gcgatgatat ctgtctcagt cttatcaaga gaaatattgt caaaaccaac atgaacagcc
     1081 ttgtcagcat aaagacctgc aaccatcatt ttttgcactt catcagctga tttgatgagg
     1141 cgcatgcgtt ggatacgagg agtgaggttg tcaaactcag cagtctcaaa aactgttttc
     1201 aaaccatggt atttggtcaa gatgagattg tcaaactcaa cagcgacacg tttgaagtca
     1261 agttgtggaa gagcatgttt gattttttgc catggatttt cagaatcgac atagcccact
     1321 actgggaagg aaacggtgct acttgcacgt tctacttcaa gagctgggac aaagaggaga
     1381 ggttcctgat ccgctaggac aaagaggaac atttggcgtt catggggatc actgtaaaaa
     1441 ccagtgaggt aattgattgt gacggggtca gatacgacag cgacgtctag tttttctgat
     1501 tcaagatatg ttaggatttg ttgtaattta gacatatgct accttctttc tacccctcta
     1561 ttttggcaaa aaatgagaga aaatgcaagg gagaagggta aaagaaaaga caaaaaactc
     1621 cgacaagata acggagttct ttgatatcat tttcctttgt ttaagaaaag tcagccttgc
     1681 ttttgacgtc actgtactct tcagcgattt cttggctgag aatgtcctca taggcaggga
     1741 gttggatgtc ctgaccatat ttcttcttga gggcagtagt aactaggcga taagccagat
     1801 tggcattacg agagaggata ggcccgtgga agtaggaacc aaagacattc ttataatgaa
     1861 ccccttcacc gaccttttct tcgttgtttc catttccata gacaacctgt cccagcggtt
     1921 tttggtcatc agagaggaag gtacgacctt ggtgattttc aaatccatag taggtttcat
     1981 cgaaatcttc attgtgaatc ttgatgtcac cgataaaacg gttattggtc tggttgagcg
     2041 tgtagtgtcc catgacccct agcccttcga tacgttttcc tgaagcttca acataatatt
     2101 gacccaatag ttggaaacca ccgcagatag ccagaactac accgtcgttt tggatgtagt
     2161 tgtcaatgct ctctttttta gcaggtaggt cgtctgcaat gatactttgt tcaaagtctt
     2221 gaccaccacc gaaaaaggcg atgtcgtagt gattttcatc aaagtcatca tggagagaaa
     2281 cgatgtcaac ggtcacatgg gctcccagtt tttcagccac atacttgagc atgaggatgt
     2341 ttccattgtc cccgtaggta ttcatgagat ttccgtagag gtgggcaatg ttgagctgat
     2401 aggggtaatt gctatctttt gaggaaagtg aagtataaac cattagttca tctcctttct
     2461 aacaatctga cgactagcca gcagttcacg aaattccagc atggcagtat aagttgccag
     2521 aatataggca tgcttgcagt cttgattctc aatggtcttg agaacttgct ccagattact
     2581 cgtttcagtg attttctcag ctggatagcc agtcactcgg aggcgacgag cgatttcaga
     2641 atgacgaaca ccgccagcgt tgatttcagg aatgtccatg tcagtgattt gctcaaagtc
     2701 tgcatcccag atccagctag tgtcaattcc atctgcatag ttggcattaa ggaggacaga
     2761 taggctaaat ggataaggtg ctagtttgat catttcgata gcttgggttg caccgactgg
     2821 atttttaatc aagacaaggg tacattcctt gtcaccgata tgaaaggttt cttggcgtcc
     2881 aaagacagca cggctcttgt caaatccctg tttgatgagt tgggaatctg cgccgaggaa
     2941 acgggcgatg gccacagcag ctagggcgtt atagatatta tagagcccgc cgatttggat
     3001 accgtattct tggccgtcta tgacaaagcg agagcgattg ttggtcaact caaccagttt
     3061 tgtcaaacga tagtcgagat caggacgttt acatccacaa ccttcacaga tataggcacc
     3121 caagtttgca taggtattat gctcatattt gaggatgcct tggcagtcag gacagagaat
     3181 cccttcggta ttgtagtgag ccagttgggc tggtcctttt tccaagtcaa aaccaaaata
     3241 ctctataggg tttggaatag ttggcttgta gaaaagtgga ctgtctccgt taaggagaac
     3301 agtagcagtt ggaacttttc gaatggcatc caatatcatg ttataggtag tatagatttc
     3361 accgaaacgg tccatctggt cacggaagat attagtaatg acaaaaagac taggctggat
     3421 atagtcacag atacgagata gactggcttc gtcaatttcg aggacggcaa tatttttccc
     3481 agtttttgaa gatttggctg ttaggaaggt tgttgcaatc cctgtaatca tgttggcacc
     3541 gcttgggttg gttagaactt gaccataaac ctcttttaaa atgccgacag tgagggcagt
     3601 tgtcagggtt tttccatttg ttccagtgac aacgacaatc tcgtagttct tagctaggct
     3661 ttgtaaaata tctttatcaa attgaagggc gactttccct gggagcgtac ttccacgtcc
     3721 aagacggctt aaaacgaagt gggaagaacg cccagcaaga aggcccaaag tagtttttaa
     3781 gttcatgttt ctattatatc acaaaagagg gaaaagacag atttggtgtt tcgtagaagt
     3841 aaaaacagcc caaagagggc tgtcagttaa gatgagattt caacttaaat cgcaaacaag
     3901 tcattcaagt tctcagccaa ggttgggtga gtgaagattt gttttgtgaa gtaagtgtaa
     3961 ggaatcttgt tgtccatagc aacagtaatg atgttgatga tttcttgaga accttctgag
     4021 aagatgcttg caccaagaat ttcttttgtt tcagtattaa caacagcttt gaaagctccg
     4081 cgaaggtctc catttacgtg accacgaggc atggctgcaa cagggatttc tttcactgcg
     4141 tatggaagtt tcaaatcagc tgcttggctt tcagtcaaac caacttgtga aagtgcaggt
     4201 gtgatgaaca tagtatttgg cacattgaga cggtcctcaa gtgtgtagct gccatctcca
     4261 gcaaggtagc tgtaaacaac acggaagtca tcaagtgaaa tgtaagtaaa ttgaaggcca
     4321 ccgttgacat ctccaactgc aaagacacca ggaacgtttg tttgacagtg tttgtctact
     4381 ttaatagcac cacgttcagt tagttcaata tctgtatttt caagttgaag tggttctaca
     4441 tttggtttgc gtccagttgc gtagagaagg gcgtcgaaac ggtaagtttc gtcttcagtt
     4501 acgacaagca cttggtcacc atcgtttttg atttcagtag tatggatatt ttgaagcaat
     4561 tcaatgccat cttcttccat gtattgttta gcaagagctg cgatggaagg ttctgcacga
     4621 ggtaggaatg tatccaaggc atctaggact gtgaccttgc ttccaagttt gttgtaaagg
     4681 ccggcaaatt caagaccgat atttccgcca ccaaggattc caagtttttc aggtaatttg
     4741 tccaagcttt ggatacctgt tgagtcaaag atgtttttgc ttgtagcaag tccaggaatt
     4801 ggcaagacgt ttgaaacagc accagtgttg atgacgattg tttcagcagt cagttctttc
     4861 ttttcatcac cagcttggat ttcgatgact ttatttgaaa ggaagtgagc ttccgcatca
     4921 aagatatcta cgcctgtacc agcaacagtc gcatagtttt taccgttgag gcgaccagtg
     4981 atcgtgtttt tagtagcaat cacttcttca aaagacaagt ccttttcagc agcaactagc
     5041 aaggttttag ttgggataca accaatgttg atacaagttc caccgtacat agccttgctg
     5101 cgttcaacga gggcaacttt tttgccagct gaagccaatt tacctgctag tgttttacca
     5161 gctttaccaa atccaataac aattaaatcg tatgttaaca tttatcttcc tcctattcga
     5221 atttcattct agcacaagaa aaaaactttt gcacaattct gctacggaaa agacagaaaa
     5281 agataaaaac gctttccaga caaaaaacta gtaatttttt gacaagcttg ataaactaaa
     5341 atcctatcta tttttatata agaaagaata aatgttcgaa aataggaggt tttatgaaat
     5401 cgaatcgtta tattattgcc tttgctgggg tcattttaca cttaatgctg ggttcgactt
     5461 atgcttggag tgtttatcgt aaccctatta ttgaaaaaac gggatgggat caggcttctg
     5521 ttgccttcgc ctttagtcta gcaatctttt gtttgggctt atcggctgca tttatggggc
     5581 gtttggtaga aaaatttggt ccgaaagtca tggggagtct atctgctttt ctatacgcag
     5641 gtggaaatat cttaacagga tttgcaatag accgtcagga actgtggttg ttgtatctag
     5701 cttatggcat tttaggtggg cttggtttgg gagcaggcta tattacccct gtgtcaacga
     5761 ttataaaatg gtttcctgat aaacgtggtc tcgcaacagg tttagcgatt atggggtttg
     5821 gttttgcttc tttattgact agtcccatag cgcaacacct catcgcaggg gtagggattg
     5881 tagaaacttt ttatatttta ggagcaagtt actttattat catgctccta gcttcacaat
     5941 tcattaagcg tccaaatgag caagagcttg caattttatc ttcttcaggg aaagaaaaaa
     6001 cagcctcttt gacgcaagga atggctgcaa atcaggctct aaaaagcaat cggttttata
     6061 tgctttggat tattttcttt atcaacatag cttgtggttt aggcttaatt tcagcggcat
     6121 cgccaatggc acaggagatg gctggcttgt ctacaagtca tgcagcagta atggtgggtg
     6181 ttttggggat tttcaatgga tttggtcgct tgctctgggc gagtttgtct gactatatcg
     6241 gtcgccctct aacctttagt atattactgc ttgtcaatct tttctctctc actttggctc
     6301 tttacagatt ccgttttatt tgtagttgct atgtctattt tgatgacttg ctatggagct
     6361 ggtttttctt tgattccagc ttatctcagt gatatttttg gaaccaagga attggccgct
     6421 ctgcatggtt atattttaac agcttgggca atggctggtt tagcgggacc tattttatta
     6481 gcagagactt ataaaatggc tcattcgtac acacaaacct tgttcgtttt tctcatttta
     6541 tacagtatcg ccttggcttt gtcttattat ctaggtcgtt caatcaaaaa agaaagtcaa
     6601 aaaccgctta catgattttc tgtagaaatg gggctatctt ttgctctggt cttgtgttat
     6661 actagatagg ttgcaaagaa aacagtactt ttcttttgtg gaaaagaagc aacacgattt
     6721 tatatctagt tatatgaaaa tacgtcataa aaagaaaagt ataaactaag ccctataggg
     6781 tggcttcgca ccacctttag aaagaagaat aacgtgaaat ttaatgaatt aaacttgtct
     6841 gctgatttgc tagcagaaat tgaaaaagct ggttttgtag aagctagtcc tatccaagaa
     6901 caaactattc ctttggccct tgaaggcaag gatgttatcg gtcaagctca gactggtaca
     6961 ggaaaaactg cagcctttgg cttgcctacc cttgaaaaaa tccgtacaga agaagcgact
     7021 atccaagctt tggtcatcgc tccaactcgt gaactagctg tccaaagtca agaagaactc
     7081 ttccgctttg gtcgtagtaa gggagtcaaa gtccgttcag tatatggcgg atcaagcatt
     7141 gaaaaacaaa ttaaggctct taaatctggt gcccatatcg tggtgggaac tccaggtcgc
     7201 ctcttggact tgattaaacg caaggccttg aaattacaag acattgaaac ccttatcctt
     7261 gacgaagcgg atgaaatgct taacatgggc ttccttgaag acatcgaagc cattatttcc
     7321 cgtgtacctg agaaccgtca aactttgctt ttctcagcaa ctatgccaga tgccatcaaa
     7381 cgtatcggtg ttcagtttat gaaagcccct gaacatgtca agattgcggc taaggaattg
     7441 acaacagaat tggttgacca gtactatatc cgtgttaagg aacaagaaaa atttgacacc
     7501 atgactcgtc tcatggatgt ggcacaacca gaactcgcta ttgtatttgg tcgtaccaaa
     7561 cgccgtgtgg atgaattgac tcgtggtttg aaaattcgtg gcttccgtgc agaaggaatt
     7621 catggcgacc tagaccaaaa caaacgtctt cgtgtccttc gtgactttaa aaatggcaat
     7681 cttgatgttt tggttgcgac agacgttgca gcgcgtggtt tggatatttc aggtgtgacc
     7741 catgtctaca actacgatat tccacaagat cctgagagtt atgttcaccg tatcggtcgt
     7801 acaggtcgtg ctggtaagtc aggtcaatct attacttttg ttgctccaaa cgaaatgggt
     7861 taccttcaaa tcattgaaaa cttgactaag aaacgcatga aaggtctcaa acctgcaagt
     7921 gtagaagaat ccttccaatc aaaaaaacag gtagctctca agaaaatcga acgtgatttt
     7981 gcagatgaaa ccattcgtgc caactttgag aaatttggta aggatgctcg caaattggct
     8041 gctgagttta ctccagaaga attggcaatg tatatcttga gtctgacagt ccaagaccca
     8101 gatagccttc cagaagtgga gattgcacgt gaaaaaccac taccgtttaa accatcaggt
     8161 aatggtttcg gtggtaaagc taagggaggt cgtggaggcc gtcgtgggga cgaccgtcga
     8221 gagcgtgatc gccgtggcaa tggtcgccgt gatgagttca aaaaaggaag tcgtggcaac
     8281 gatcgttttg ataaggaaaa acgttaccgt aaggataata aaaaaccacg caatacttta
     8341 agcgaaaagc aaacaggctt tgttattcgt aacaaaggcg ataaataaga aaaagcggtt
     8401 caaaatgaat cgctttttta tataaggaga ccgaatgtga aaagacaaat aaaattacta
     8461 tattatcttt tataatgtta tgatacacaa aaataggcaa cttgtcaata gaaaaggaac
     8521 aatttaatta aaaatattct ggtttttaat taaattgtaa gtcaatgcaa gtcaataagg
     8581 aattttcaga taattattga aaaagagacg tttttatgtt ataatgatag cgattaaatt
     8641 cgaggtgaaa aatggcacat ttattagaaa aaactagaaa aattacatca attttgaaac
     8701 gctcagagga gcagttgcag gatgagctcc cttacaacgc tattacgcgt cagttagcgg
     8761 atattattca ttgcaatgcc tgcattatca atagtaaggg acgtctgctt ggctatttta
     8821 tgcgttataa aacaaataca gatcgcgtag agcaattctt ccaaactaag attttcccag
     8881 atgactacgt tcaaggggct aatatgattt acgaaacaga agcaaacttg cctgttgagc
     8941 atgatatgag tattttccct gttgagagta gagatgattt tccagatggc ttgacgacta
     9001 ttgcaccgat tcatgtatcg gggattcgcc ttggttcttt gattatttgg cgtaatgata
     9061 aaaaattcga agatgaggac ttggttcttg ttgagattgc cagtaccgtt gttgggattc
     9121 agcttcttaa cttccaacgt gaagaagatg agaaaaatat tcgtcgtcgt actgctgtca
     9181 ccatggcggt caataccctt tcttactccg aactccgtgc tgtttcagca attttagggg
     9241 aattaaatgg aaatgaaggg aagttgactg cgtcagtgat tgcagatcgt atcggaatca
     9301 ctcgctctgt gattgtcaat gctcttcgta aacttgagtc tgcggggatt attgaaagtc
     9361 gctcacttgg aatgaaggga acctatctta aggtcttgat ttcagatatt tttgaagaag
     9421 tgaagaaaag agattactaa tgacaaaggc tttaatttcg attgattata cagaagattt
     9481 tgttgctgat agtgggaagc tgacagcagg tgctccagct caggcgattt cggatgccat
     9541 cagcaaggta actcgattag cttttgaacg aggagattat atcttcttta ctattgatgc
     9601 tcatgaagaa aacgattttt tccatccgga aagtaagtta tttcctcctc ataatctgat
     9661 tgggacgagt ggacggaatt tatatggaga tttggggatc ttttatcaag agcatggttc
     9721 agacagtcgt gtcttttgga tggataaacg ccattactca gctttttcag ggactgacct
     9781 agatattcgt ttgagagagc gtagagtgtc taccgttatc ttaacaggtg tcttgacgga
     9841 tatctgtgtc ctacatacag ctatagatgc ctataatcta ggatatgaca tcgagattgt
     9901 taaaccagct gttgcttcca tctggcctga aaatcatcaa tttgccctag gtcatttcaa
     9961 aaatacactc ggagctaagt tagtagatga aaatctaaat gaactttctg agtaacctgg
    10021 ttggtgaaaa tgaaaaaatt tgaaaaaaag tgttgacaag catcccaaaa gttgatatac
    10081 tagtaaagta atcgatgcgg ggatggcgga attggcagac gcgcaggact aaggatcctg
    10141 tgaccgcttt aggtcgtgag ggttcaagtc cctctctccg cataggaaaa gagttagcta
    10201 aagctagctc ttttgtattt ctctaaaaaa ttagaatcca gtcaaatgta gtggagaatc
    10261 agcgaaaata tgggaaaact gttccttgtt tctgcttttg tcatagaaga ataataaaga
    10321 ttatcttctt caaattctcc gatattctct aaagttttgt gcaagttgca cagaactttt
    10381 ttattttttt ggtcatcttg ccatagaaat ataaagcgtt ttcatctata atataattat
    10441 caaaagacaa aaggagttca cctcatggta gaattgaatc ttaaaaatat ttacaaaaaa
    10501 tatccaaaca gcgaacacta ttcagttgaa gatttcaact tgaacatcaa agataaagaa
    10561 tttatcgttt tcgtaggacc ttcaggatgt ggtaaatcaa ctacactccg tatgattgct
    10621 ggtcttgaag acattacaga aggtactgca tctatcgatg gcgtggttgt caacgacgta
    10681 gctccaaaag accgtgatat cgccatggta ttccaaaact acgctcttta cccacacatg
    10741 actgtttatg acaacatggc tttcggtttg aaattgcgta aatacagcaa agaagacatt
    10801 aacaaacgtg ttcaagaagc agctgaaata cttggattga aagaattctt ggaacgtaaa
    10861 ccagctgacc tttcaggtgg tcaacgtcaa cgtgttgcca tggggcgtgc gattgtccgt
    10921 gatgcgaaag tattcttgat ggacgaacct ttgtcaaact tggatgccaa acttcgtgta
    10981 tcaatgcgtg ctgaaatcgc taaaattcac cgtcgtatcg gagctacaac tatctatgta
    11041 actcacgacc aaacagaagc gatgacactt gcagaccgta tcgttattat gtcagctact
    11101 aagaaccctg ctggtacagg tactatcgga cgtgtagaac aaatcggtac tcctcaagaa
    11161 gtttacaaaa atccagttaa caaattcgtt gcaggattca tcggaagccc agctatgaac
    11221 ttcatcaacg tgaaattggt tggtagcgaa attgtttctg acggtttccg tttgaaagtg
    11281 ccagaaggag cattgaaagt tcttcgtgaa aaaggctacg aaggaaaaga attgatcttt
    11341 ggtatccgtc cagaagacgt gaatgcagaa cctgctttcc ttgaaacatt cccagactgt
    11401 gttgtaaaag cgactatctc tgtatcagaa ctgcttggtt cagaatctca cctttactgc
    11461 caagttggta aagacgagtt tgttgcaaaa gttgatgctc gtgactactt gcaaacaggt
    11521 gcaacagttg agcttggatt tgacttgaac aaagcacact tcttcgatgt agaaactgaa
    11581 aaaacaatct actaaaataa ataaaattca aagcactaca agaaaagata tctctttatc
    11641 aattgtagtg gagagatatc agttaatcta gggagagaaa caaaatgctt ctctcctttt
    11701 tgctagggaa gtcatattat gcatctatat tgtgatgctc tttaatactc ttcgaaaatc
    11761 tcttcaaacc acgtcaacgt cgccttgccg tacgtatgat tactgatttc gtcagtttta
    11821 tctgcaacct caaagatgta ctttgagcag cttacggcta gtttcctagt ttgctctttg
    11881 atttccattg agtattattt gtgggtacca tctacaagtg aagctatatg cgtaaactac
    11941 gtgagcaatt gaattcgaac tagagaggta ataataaatt tatgctatag ttatggtgac
    12001 ttgtatgctt ttgattctag tttatcaaat aatagattag aattgtcaga taatatcatt
    12061 ttgtgttata atgaagaaaa aacagaggtg ttcaaatgtc agaagcaggt cataagtttt
    12121 tagcaaaatt ggggaaaaaa cgcttacgtc caggtggaaa gcgtgctaca gattggttaa
    12181 ttgcagaagg aggattgtca aaagaaaaga gaatactaga ggttgcgtgt aataggggaa
    12241 ctacagcaat tgagttggca cagcgttttg gttgcaagat aactgctgtt gatatggatg
    12301 ctcaagcttt agaagtggct aaaaaatctg ctggaacggc aggtgttgct catttaatca
    12361 gttttgaaag agcaaatgca atgaaacttc cttatcaaga tgctagtttt gatattgtta
    12421 taaatgaagc tatgctgact atgcaagccg atcaagctaa gaaaaaatgt gtaatggaat
    12481 atctaagggt attaaaacct ggaggtcttc ttttgacaca tgatgtgctt cttaaggaag
    12541 ctaaagagtc tatcagacag gaattatcac aagcaattca tgtaaatgta ggtcctttaa
    12601 ctcaagatgg ttgggaacag gtgatgatag aatcaggtta ttgtgatgtg aaagtattga
    12661 ctggtgaaat gacattaatg aaattatcgg gtatgattta tgacgaaggt tggctaggaa
    12721 ctttgaaaat ttgtgtaaat gcttgtaaaa aggagaatag aaagcagttt ttaactatgt
    12781 ataaaatgtt tgctaagaat aaacagaaat tgggctttat tgcgatggct agttataaat
    12841 cgtcaaaacg ttagataatt attgaagtta acttttcctt ttttctttct taaaaaatat
    12901 gctataatag agagtgaaaa actttgaaag aaagaaaaag atgaatttaa aagattacat
    12961 tgcaacaatt gaaaattatc caaaggaagg cattaccttc cgtgatatta gtcctttgat
    13021 ggctgatgga aatgcttata gctacgctgt tcgtgaaatc gttcagtatg ctactgacaa
    13081 gaaagtcgac atgatcgtgg gacctgaagc tcgtggattt atcgtgggtt gtccagttgc
    13141 ctttgagttg ggaattggtt ttgcgcctgt tcgtaagcca ggtaaattgc cacgcgaagt
    13201 tatttctgct gactatgaaa aagagtacgg tgtcgatacc ttgactatgc acgcggatgc
    13261 cattaagcca ggtcaacgtg ttcttattgt agatgacctt ttggcgacag gtggaactgt
    13321 taaggcaact atcgagatga ttgaaaaact tggtggtgtt atggcaggtt gtgccttcct
    13381 tgttgaattg gatgaattga acggccgtga aaaaatcggt gactacgact acaaagttct
    13441 tatgcattat taatgaaaac agtccctagg gctgttttct ctacactagg atataaaaat
    13501 agactataac tagttagaga aaaactataa ttgaaaacta tatcttcttg cagtataata
    13561 aaaggactaa gtgtttgaga tttgtcttca aacacatgca attattcctg agagagtaca
    13621 gttaggagag ggttatgccg attcgaattg ataaaaaatt gccagctgtt gagattttac
    13681 ggacagagaa tatctttgtc atggatgatc aacgtgctgc ccaccaagat atccgtcctt
    13741 tgaagatttt aattttaaat ctcatgccac agaaaatggt cacagagacc cagttgttgc
    13801 gtcacttggc taatacaccc ctacaactgg atattgattt tctctatatg gagagccacc
    13861 gttctaaaac aactcgttca gagcacatgg agaccttcta taaaactttt cctgaagtca
    13921 aggatgagta ttttgatggg atgatcatca cgggtgctcc agttgagcat ttaccatttg
    13981 aggaagtgga ctattgggag gaatttaggc agatgcttga gtggtctaag acacatgtct
    14041 attcgaccct tcatatctgt tggggggctc aggctgggct ttatctgcgc tatggtgtag
    14101 aaaaatacca gatggacagt aagctatcag gtatttatcc tcaggacacc ctaaaagagg
    14161 gtcaccttct atttagaggc tttgatgata gctatgtatc ccctcattca cggcacacgg
    14221 agatttctaa ggaagaggtc ttaaacaaga ccaatctcga gattttatca gaaggacctc
    14281 aggttggggt ttctattttg gccagtcgtg atttacgaga aatttatagt tttggtcatt
    14341 tggagtatga ccgtgatacc ttggcaaaag agtattttcg agatcgtgat gcaggtttcg
    14401 acccacatat tccagaaaat tactttaaag atgatgatgt taatcaggta ccttgtcttt
    14461 gttggtcttc atctgcagcc ctctttttca gtaattgggt aaaccatgcg gtctatcagg
    14521 agacgccttt tgattggaga aagatagaag atgatgcatc tgcatatggg tatttataag
    14581 aggaattatg acatatttag acgcttttaa atcaggtacc ttggttttac cgagtgccct
    14641 gctcttgcat tttaaggaac tctttccttc tagcgacgat tttctggttt ggcaattttt
    14701 ctatttgcaa aatacgacag gcttagaaga aatgtcgcca agccagattg ctgaaaggat
    14761 tggcaaggaa atttcggatg tcaaccagtc catttctaat ctgacggaaa ggggactgct
    14821 ccagtatcgt actatcgaat taaatggcga aattgaattg ctctttgatg ctagtttggc
    14881 cttggaacgt ttggatgacc tgtttggagc agttcgttca agttcagacc agctaacacc
    14941 tcaaaaccag ctcaaggatt tggtggaaac cttccagcag gagttgggac gattgttgac
    15001 gccttttgag attgaggatt tgaccaagac actaaaggaa gatggaacca gtgctgactt
    15061 gattaaggag gctcttcgtg aagctgtttt gaatggaaaa ccaaactgga agtacattca
    15121 ggcgattttg agaaactggc gccatgaagg aatcaagagt gtggctcaaa ttgaggccaa
    15181 gagagcagaa agagaagcaa gcaatcctca gttgacacag gtatctgcag atttcagaaa
    15241 tgccatggat ctctggaagg attaatccat gcaagtaggc ttgaaatccg agtaagattt
    15301 gcaagctgtg tataattgtg atagaataaa tagaaaataa attgaaaaaa gaggtatgtg
    15361 aaatgtcacg taaaccattt atcgctggta actggaaaat gaacaaaaat ccagaagaag
    15421 ctaaagcatt cgttgaagca gttgcatcaa aacttccttc atcagatctt gttgaagcag
    15481 gtatcgctgc tccagctctt gatttgacaa ctgttcttgc tgttgcaaaa ggctcaaacc
    15541 ttaaagttgc tgctcaaaac tgctactttg aaaatgcagg tgctttcact ggtgaaacta
    15601 gcccacaagt tttgaaagaa atcggtactg attacgttgt tatcggtcac tcagaacgcc
    15661 gtgactactt ccatgaaact gacgaagata tcaacaaaaa agcaaaagca atctttgcga
    15721 acggtatgct tccaatcatc tgttgtggtg aatcacttga aacttacgaa gctggtaaag
    15781 ctgctgaatt cgtaggtgct caagtatctg ctgcattggc tggattgact gctgaacaag
    15841 ttgctgcctc agttatcgct tatgagccaa tctgggctat cggtactggt aaatcagctt
    15901 cacaagacga tgcacaaaaa atgtgtaaag ttgttcgtga cgttgtagct gctgactttg
    15961 gtcaagaagt cgcagacaaa gttcgtgttc aatacggtgg ttctgttaaa cctgaaaatg
    16021 ttgcttcata catggcttgc ccagacgttg acggtgccct tgtaggtggt gcgtcacttg
    16081 aagctgaaag cttcttggct ttgcttgact ttgtaaaata atcagtaagt agcaaaagct
    16141 aggtggaaca gcattcagat gtctgttaca ttttttatag gagaggaaag attgaaaaca
    16201 aaaattggat tagcaagtat ctgtttacta ggcttggcaa ctagtcatgt cgctgcaaat
    16261 gaaactgaag tagcaaaaac ttcgcaggat acaacgacag cttcaagtag ttcagagcaa
    16321 aatcagtctt ctaataaaac gcaaacgagc acagaagtac agactaatgc tgctgcccac
    16381 tgggatgggg attattatgt aaaggatgat ggctctaaag ctcaaagtga atggattttt
    16441 gacaactact ataaggcctg gttttatatt aattcagatg gtcgttactc gcagaatgaa
    16501 tggcatggaa attactacct gaaatcaggt ggatatatgg cccaaaacga gtggatctat
    16561 gacagtaatt acaagagttg gttttatctc aagtcagatg gggcttatgc tcatcaagaa
    16621 tggcaattga ttggaaataa gtggtactac ttcaagaagt ggggttacat ggctaaaagc
    16681 caatggcaag gaagttattt cttgaatggt caaggagcta tgatgcaaaa tgaatggctc
    16741 tatgatccag cctattctgc ttatttttat ctaaaatccg atggaactta tgctaaccaa
    16801 gagtggcaaa aagtgggcgg aaaatggtac tatttcaaga agtggggcta tatggctcgg
    16861 aatgagtggc aaggcaacta ctatttgact ggaagtggtg ctatggcgac tgacgaagtg
    16921 attatggatg gtgctcgcta tatctttgcg gcctctggtg agctcaaaga aaagaaagat
    16981 ttgaatgtcg gctgggttca cagagatggt aaacgctatt tctttaataa tagagaagaa
    17041 caagtgggaa ccgaacatgc taagaaaatc attgatatta gtgagcacaa tggtcgtatc
    17101 aatgattgga aaaaggttat tgatgagaac gaggtggatg gtgtcattgt tcgtctaggt
    17161 tatagcggta aagaagacaa ggaattggcg cataacatta aggagttaaa ccgtctggga
    17221 attccttatg gtgtctatct ctatacctat gctgaaaatg agaccgatgc tgagagtgac
    17281 gctaaacaga ccattgaact tataaagaaa tacaatatga acctgtctta ccctatctat
    17341 tatgatgttg agaattggga atatgtaaat aagagcaaga gagctccaag tgatacaggc
    17401 acttgggtta aaatcatcaa caagtacatg gacacgatga agcaggcggg ttatcaaaat
    17461 gtgtatgtct atagctatcg tagtttatta cagacgcgtt taaaacaccc agatatttta
    17521 aaacatgtaa actgggtagc ggcctatacg aatgctttag aatgggaaaa ccctcattat
    17581 tcaggaaaaa aaggttggca atatacctct tctgaataca tgaaaggaat ccaagggcgc
    17641 gtagatgtca gcgtttggta ttaagcgatg atttgaaaga gggatgtgat agtagcaccc
    17701 tctttttctt tgttttatga tagttcatcc tcgagtaaat tcaagttctt gctcggaaat
    17761 gaagcttata tagtagattg aatatagaca aataccttgt gattggtaaa acattttaga
    17821 aattcattta cctttcctaa tcgacttggt ttcatcttat ttcaatctat tatagtattg
    17881 gggaatttct tcaaaccaca tcagcttggt cagttctacc tgcgacctca aaacttgtgc
    17941 tttggtcaag ctgggtttag tttcctagtt tgctgatgga tttccattga ctataagcat
    18001 ccaaccctct ttttgtcttc taaagaattc ttaaattatc agtctattgc aacttttctc
    18061 atataagttc tttgtcttgc tattggtttt ccttagtagt atactaaggt agtaatcatt
    18121 aagaagtggt tacaaaaaat aatgaatgag gtaaagaaaa tggtagaatt gaaaaaagaa
    18181 gcagtaaaag acgtaacatc attgacaaaa gcagcgccag tagcattggc aaaaacaaag
    18241 gaagtcttga accaagctgt tgctgatttg tatgtagctc acgttgcttt gcaccaagtg
    18301 cactggtata tgcatggtcg tggtttcctt gtatggcatc caaaaatgga tgagtacatg
    18361 gaagctcttg acggtcaatt ggatgaaatc agtgaacgct tgattacact cggtggaagc
    18421 ccattctcta cattgacaga gttccttcaa aatagtgaaa tcgaagaaga agctggtgaa
    18481 taccgtaatg ttgaagaaag cttggaacgt gttcttgtta tctaccgtta cttgtcagaa
    18541 cttttccaaa aaggtttgga tgtcactgat gaagaaggtg acgatgtgac aaacggtatc
    18601 tttgcaggcg ctaaaactga aacagataaa acaatttgga tgcttgcagc cgaacttgga
    18661 caagcacctg gtttgtaaga aataaggaaa catagataaa tctgtaggaa atttcttaca
    18721 gattttttct attttgtaag ctattccaaa ccagtctttt tttgagtttt ttgataaaat
    18781 agtactatca gtgaaaagga tggaagcatg actaagaaaa tcgtagctat ttgggcccag
    18841 gatgaagagg gtgtgattgg taaggaaaat cgtctgcctt ggcatttgcc agcagaattg
    18901 cagcacttta aagaaacaac tctgaatcat gctatcttga tggggcgtgt gacctttgat
    18961 gggatggggc gtcgcttgct tccaaaacgg gaaaccttga ttttgacgcg taatccggaa
    19021 gaaaagatag atggggttgc tacttttcag gacgtccagt ctgttcttga ctggtatcag
    19081 gctcaagaaa agaatctcta cattatcggt gggaagcaaa tttttcaggc ttttgaacct
    19141 taccttgatg aagtgattgt cactcacatt catgctcggg tggaaggaga tacctatttc
    19201 cctgaagaac ttgacttgtc tctttttgag acagtttcaa gcaaatttta cgccaaagat
    19261 gagaagaatc cttatgattt taccatccaa taccgcaaga gaaaggaagt ctaatggaac
    19321 ggagtttatt tggtctattc acggcttttc tgtgtttcat ctgctttctg gcaggagcac
    19381 aagcttttcg taaaaagcgt tacgggcttt ctatcctcct ttggttaaat gcctttacca
    19441 atctggtcaa tagtattcat gctttttaca tgaccttatt ttagatagaa tgacagtata
    19501 gaatggaagg aaatcatgtc tacaaataga aaaaatgata tgatggttta ttgctcattt
    19561 tgtggcaaaa accaagaaga agtacaaaaa ataattgctg gcaacaatgc ttttatttgt
    19621 aatgaatgcg tggagttagc tcaggaaatc attcgagaag aattggttga ggaagtcttg
    19681 gcagacttgt ctgaggtgcc aaaaccaatt gaactcctcc atatcttgaa ccactatgta
    19741 attggtcaag atcgtgccaa gcgtgccttg gcagtggcgg tttataacca ctacaaacgc
    19801 atcaatttcc acgatacacg cgaagagtca gaagatgtgg atttgcagaa gtcaaacatt
    19861 ttgatgattg gcccaactgg ttcagggaaa actttccttg cccagacctt ggctaagagc
    19921 ttgaatgtac cttttgctat tgcggatgcg acagctctga cggaggctgg ttatgtgggt
    19981 gaggatgtgg aaaatatact cctcaaactc ttgcaggttg ctgactttaa catcgaacgt
    20041 gcagagcgtg gcattatcta tgtggatgaa attgacaaga ttgccaagaa gagtgagaat
    20101 gtgtctatca cacgtgatgt ttctggtgaa ggggtgcaac aagcccttct caagattatt
    20161 gagggaactg ttgctagcgt accgcctcaa ggtggacgca aacatccaca acaagagatg
    20221 attcaagtgg atacaaaaaa tatcctcttc atcgtgggtg gtgcttttga tggtattgaa
    20281 gaaattgtca aacaacgtct gggtgaaaaa gtcatcggat ttggtcaaaa caataaggcg
    20341 attgacgaaa acagctcata catgcaagaa atcatcgctg aagacattca aaaatttggt
    20401 attatccctg agttgattgg acgcttgcct gtttttgcgg ctcttgagca attgaccgtt
    20461 gatgacttgg ttcgcatctt gaaagagcca agaaatgcct tggtgaaaca ataccaaacc
    20521 ttgctttctt atgatgatgt tgagttggaa tttgacgacg aagcccttca agagattgct
    20581 aataaagcaa tcgaacggaa gacaggggcg cgtggacttc gctccatcat cgaagaaacc
    20641 atgctagatg ttatgtttga ggtgccgagt caggaaaatg tgaaattggt tcgtatcact
    20701 aaagaaactg tcgatggaac ggataaaccg atcctagaaa cagcctagag gtgactatgg
    20761 aacttaatac acacaatgct gaaatcttgc tcagtgcagc taataagtcc cactatccgc
    20821 aggatgaact gccagagatt gccctagcag ggcgttcaaa tgttggtaaa tccagcttta
    20881 tcaacactat gttgaaccgt aagaatctcg cccgtacatc aggaaaacct ggtaaaaccc
    20941 agctcctgaa cttttttaac attgatgaca agatgcgctt tgtggatgtg cctggttatg
    21001 gctatgctcg tgtttctaaa aaggaacgtg aaaagtgggg gtgcatgatt gaggagtact
    21061 taacgactcg ggaaaatctc cgtgcggttg tcagtctagt tgaccttcgt catgacccgt
    21121 cagcagatga tgtgcagatg tacgaatttc tcaagtatta tgagattcca gtcatcattg
    21181 tggcgaccaa ggcggacaag attcctcgtg gtaaatggaa caagcatgaa tcagcaatca
    21241 aaaagaaatt aaactttgac ccaagtgacg atttcatcct cttttcatct gtcagcaagg
    21301 cagggatgga tgaggcttgg gatgcaatct tagaaaaatt gtgaggaaaa gaaaatggca
    21361 aaaacaattc atacagataa ggccccaaag gctatcggac cctatgttca aggaaaaatc
    21421 gttggcaacc ttttgtttgc tagcggtcaa gttcccctat cccctgaaac tggggaaatt
    21481 gtaggagaga atatccaaga acagacagag caagtcttga aaaacatcgg tgctattttg
    21541 gcagaagcag gaacagactt tgaccatgtt gtcaaaacaa cttgcttctt gagcgatatg
    21601 aacgactttg ttccttttaa tgaggtttac caaacggcct tcaaagagga attcccagct
    21661 cgttcagctg tggaggtagc tcgtcttcct cgtgatgtaa aagtcgaaat tgaagtcatc
    21721 gcagagattg gataagctag ttgaagtttg gtgttgccaa acttcttttg atataaggag
    21781 aaaaagatga caaagaaaca acttcacttg gtgattgtga cagggatgag tggcgcaggg
    21841 aaaactgtag ccattcagtc cttcgaggat ctaggttatt tcaccattga taatatgccg
    21901 ccagctctct tgcctaagtt tttgcagctg gttgaaatta aggaagataa tcctaagttg
    21961 gctttggtag tggatatgcg tagccgttct ttcttttcag agattcaagc tgttttggat
    22021 gagttggaaa atcaagatgg tttggatttc aaaatcctct ttttggatgc ggctgataag
    22081 gaattggtcg ctcgttacaa ggaaaccaga cggagtcacc cactagcagc agacggtcgt
    22141 attttagatg gaatcaagtt ggaacgtgaa ctcttggcac ctttgaaaaa tatgagccaa
    22201 aatgtggtgg atacgactga actcactcca cgtgaactgc gcaaaaccct tgcagagcag
    22261 ttttcagacc aagaacaagc ccagtctttc cgtatcgaag tcatgtcttt cggatttaag
    22321 tatggaatcc cgattgatgc ggacttggtc tttgatgtcc gtttcttgcc aaatccctat
    22381 tatctaccag aactgagaaa ccaaacgggt gtggatgaac ctgtttatga ttatgtcatg
    22441 aaccatcctg agtcagaaga cttttatcaa catttattgg ccttgattga gccgattctg
    22501 ccaagttacc aaaaggaagg taagtccgtt ttgaccattg ctatgggatg tacgggtgga
    22561 caacaccgta gtgtggcatt tgctaaacgc ttggcgcagg acttatccaa gaattggtct
    22621 gttaatgaag ggcatcgcga caaagaccgc agaaaggaaa cggtaaaccg ttcatgagaa
    22681 aaccaaagat aacggtgatt ggtggaggga ctggaattcc cgtcattcta aaaagtctgc
    22741 gggaaaaaga tgtggaaatc gcagctatcg tgacggtggc agatgatggt ggttcttcag
    22801 gtgaactccg aaaaaatatg caacagttga caccgccagg tgatcttcgt aatgtccttg
    22861 tggccatgtc ggatatgcct aagttttatg agaaggtctt tcagtatcgg ttctctgagg
    22921 atgccggagc ctttgctggc catccattgg gaaatctcat cattgctggc ttgtcagaaa
    22981 tgcagggttc aacctataat gccatgcagt tattgagcaa atttttccat acaacaggga
    23041 aaatttatcc ttccagtgac catcctttga cccttcatgc agtctttcag gatgggacag
    23101 aagtggctgg agagagtcat attgtagacc atcgaggcat aattgacaat gtctatgtga
    23161 ccaatgccct aaacgatgat acgcctctgg ccagccgtcg agtagtgcag accatccttg
    23221 aaagtgacat gattgtccta gggccaggtt ccctctttac ctctattttg cccaatatcg
    23281 tgattaagga aattgggcgg gctcttttgg aaactaaggc agaaattgcc tatgtctgca
    23341 atatcatgac ccaacgtggg gagacggaac actttacaga tagcgaccac gtggaagtct
    23401 tgcatcgtca ccttggtcgc ccttttatcg acactgtctt ggtgaatatt gaaaaagtgc
    23461 ctcaggaata catgaattcc aaccgttttg atgaatactt ggtgcaagtg gaacacgatt
    23521 ttgtaggtct ttgtaagcaa gtttcgcgcg tgatttcatc taacttcctt cgtctggaaa
    23581 atggcggtgc cttccacgat ggagatttga ttgtggacga gttgatgcgc attatacagg
    23641 tgaaaaaatg agtttcacag tagcagtaaa agaagaaatc ctgggccaac accatctgag
    23701 ccggcatgaa ttatctgcca ttatcaaaat gtctggtagc atcggtctct cgacttcggg
    23761 cttgactttg tcagttgtga cagaaaatgc caaactggcc cgtcacctct atgagtcctt
    23821 tctccatttc tatgaaatca aatctgaaat tcgtcaccac caacggagca atcttcgcaa
    23881 gaatcgcgtc tataccgttt ttacagatga aaaggtgcag gatttgttaa gtgatttgca
    23941 cttggcagac tctttctttg gcctggaaac aggtattgat gaggcgattt tatcggatga
    24001 ggaagcaggt cgtgcctatc tctgtggcgc tttcttggca aatgggagca ttcgtgaccc
    24061 tgagtcaggc aagtaccagt tggaaatcag ttctgtttat ctggaccacg cgcaaggaat
    24121 tgcctccctt ctccaacagt ttttactgga tgccaaggtg cttgagcgca agaagggggc
    24181 tgtgacctat ctccagcgag cagaagacat tatggacttc ttgatagtaa tcggagccat
    24241 gcaggcacgt gatgattttg agcgggttaa gattttgcga gaaacccgta acgacctcaa
    24301 tcgggctaat aatgccgaga cagctaatat cgctcggaca gtttctgcca gcatgaagac
    24361 cattaacaat atcagtaaaa taaaagatat catgggctta gaaaatttgc cagtagattt
    24421 gcaggaagtg gcgcaactga ggattcagca cccagactac tctatccagc agttagcaga
    24481 tagtctcagc acccctctga ccaaaagtgg tgtcaatcac agactcagaa aaatcaataa
    24541 gatagcggat gaattataaa accacgaatc ctatgtgact cgtggttctt ttttataaac
    24601 tggtagagtg ttttggttgt actttttgtt cagggtcaat gtagttgata gcgttgttga
    24661 cagcagttgg agcttctccg aggcctgtcg caatcagatc aatttttccg tcatagtagc
    24721 agcagtcacc gatagcatag atacctgctt ggctggattc ctgtttgctg ttgacgataa
    24781 tcttgtgacg gttgaggtcg agcccccagt ttttaaggtt accgacagaa gatttgaaac
    24841 catagttgac aaagaggtgg tctaggtcaa tggtttcagt ttcatcagat ttgacttttg
    24901 tgatttcaag tttatcaagt gtttttccat ttccaaggag ttggctaggg gcgaatggtg
    24961 tcttgatggt tacagatgat tcttgcaagg cttgaacact gtgttccaag gcacggaaat
    25021 tatctctgcg gtgaacaagg gtagttggtg cgattttttc aaaagccaaa gtccaatcca
    25081 cagccgagtc tcccccacca agaatcgtca cttttttacc agcgtattgc tgaatgttag
    25141 aaacgtggta gtggatattt tcatagccct caaccccttc aagttccagc ggacgtggtt
    25201 tgaaggcacc gccacccata gcgatgataa ctgttttagt caggtgactt cctttagaag
    25261 ttgtgatggc aaattcttct tcttgtttgt caatctcaag aaccgtttca ttgagatgaa
    25321 taggggtatc aaatccattt agctgttcaa tcaagcggtt agtcaactct tctccagtca
    25381 ggtttgggaa gcctggtacg tctaggattt ccttttcagg gtagagaata gcaggttgtc
    25441 cacctagctg gggaagagag tcgatgattt gaaccttggc ttggcgtagg tgggcataaa
    25501 aggctgcaaa aagcccgaca ggaccaccac ccacaatggt aatatcatag agttgagaca
    25561 tagtttctcc tttgtttttt ctagtcagtt tattttatca tatttttgtt caatgtaaaa
    25621 tggactagga tagggaaaaa aatgccagaa aatggtataa taggacgaaa gtgttttgat
    25681 agggaggata tcagggatga attttcaaca attatccaat ttgcaatatt ggaccagttt
    25741 gtttgcaagt ccatggacga tagctatcaa tctgattgat attttgattg ttgcttatat
    25801 tttataccat tttacaaaag ctattgcagg aaccaagatt atgattttgg tacgtggagt
    25861 tttggtattt attttagctc aaatccttgc aaatatgatt ggtttgacta cgatttcttg
    25921 gttaatcaat caaattatta cttatggggt tattgcggcg gttgttatct tctctccaga
    25981 gattcggact ggtttggaac gtttgggaag agcgacagat ttcttttcca atgcccctat
    26041 tagtgctgag gaacagatga ttcgtgcctt tgttaagtct gttgaataca tgagtcctcg
    26101 taaaatcggg gccttggttg ctattcagcg tgtacgtacc ttgcaggagt atatttcgac
    26161 aggaattccc ttggatgcta agatttctgc agaacttctc attaacattt ttattcccaa
    26221 cactccccta catgacggtg cggtgattat caaagaagaa cgtatcgctg tgacgtctgc
    26281 ctatctgccc ttgacaaaaa acacagggat ttccaaggaa tttgggacca gacaccgggc
    26341 ggctatcggt ttatcagaag tctcagatgc cttgactttt gtcgtatcag aggaaacggg
    26401 aggaatttcg ataacctata atggaaggtt taagcacaac ctaacacttg atgaatttga
    26461 aacagaatta cgtgaaatct tacttccaaa agaggaagta ggtcttagtt ttaaagaacg
    26521 attgctagga ggatggaaac atgaaaaaaa atagtttata tatcatatcc tcactctttt
    26581 ttgcttgtgt cttatttgtc tatgctacgg cgacgaattt tcaaaacagt accagtgcta
    26641 ggcaggtaaa aacggaaacc tatactaata cagtaacaaa tgtccctatt gacatacgct
    26701 ataatagtga taagtatttt attagcggtt ttgcttcaga agtatcagtg gtcttgactg
    26761 gtgcaaatcg cctatcgcta gctagtgaaa tgcaagaaag tacacgtaaa ttcaaggtta
    26821 ctgctgacct aacagatgcc ggtgttggaa caattgaagt tcctttgagc attgaagatt
    26881 tacccaatgg gctgaccgct gtggcgactc cgcaaaaaat tacagtcaag attggtaaga
    26941 aggctcagaa ggataaggta aagattgtac cagagattga ccctagtcaa attgatagtc
    27001 gggtacaaat tgaaaatgtc atggtgtcag ataaagaagt gtcgattacg agtgaccaag
    27061 agacattgga tagaattgat aagattatcg ctgtcttgcc aactagcgaa cgcataacag
    27121 gtaattacag tggttcagta cctttgcagg caatcgaccg caatggtgtt gtcttaccgg
    27181 cagttatcac tccgtttgat acaataatga aggtgactac aaaaccagta gcaccaagtt
    27241 caagcacatc aaattcaagt acaagcagtt catcggagac atcttcgtca acgaaagcaa
    27301 ctagttcaaa aacgaattaa aaatagaaaa ggattttata acaatgggta aatattttgg
    27361 gactgatgga gtccgtggag aagctaacct agaactaaca ccagaattag cctttaaact
    27421 aggacgtttt ggaggctatg ttcttagtca acatgaaacg gaagcgccga aagtctttgt
    27481 aggacgtgac acacgtattt caggggaaat gctagaatcg gccttggtgg caggtctcct
    27541 ttcagtaggg attcacgtat acaaacttgg tgtccttgca acaccagcag tagcttactt
    27601 ggttgaaact gaaggagcaa gtgctggtgt catgatttct gctagccaca atccagctct
    27661 tgataacgga atcaagttct ttggcggtga tggcttcaaa ctagatgatg aaaaagaagc
    27721 agaaattgaa gccttgctag atgctgagga agacactctt cctcgtccaa gtgcagaagg
    27781 cttaggaatt ttggtagatt atccagaagg cttgcgtaag tatgaaggat accttgtttc
    27841 aactggaact cctcttgatg gaatgaaggt tgccttggat acagctaatg gagcagcttc
    27901 taccagtgcc cgtcaaatct ttgcagacct tggtgcccaa ttgacggtta tcggggaaac
    27961 accagacggt cttaacatca accttaatgt tggttcaaca catccagaag cccttcaaga
    28021 agtggtcaaa gaaagtgggt cagctattgg tttggccttt gatggagaca gtgaccgctt
    28081 gattgctgtt gatgagaatg gtgacatcgt cgatggtgac aagattatgt acatcatcgg
    28141 aaaatacctt tctgaaaaag gacaattggc tcaaaataca attgtgacaa ctgttatgtc
    28201 taaccttggt ttccacaagg ccttgaatcg cgaaggtatt aacaaggcag ttactgcagt
    28261 tggtgaccgc tacgttgttg aagaaatgag aaaatcaggt tacaaccttg gtggtgaaca
    28321 gtctggtcac gttatcttga tggattacaa taccacaggt gatggtcaat tatcagcaat
    28381 tcaattgact aaaatcatga aggaaactgg taagagctta tcagagttgg cggcagaagt
    28441 aacgatttat ccacaaaaat tagttaatat ccgagtggaa aacgtcatga aggaaaaggc
    28501 catggaagtg ccagctatca aggccatcat cgagaagatg gaagaagaaa tggcggggaa
    28561 cggccgtatc cttgttcgtc caagtggaac agagcccctc ttgcgtgtta tggcagaagc
    28621 gcctacaaca gaagaagtgg actactatgt tgatactatc acagatgtag ttcgtgctga
    28681 aattgggatt gactaaatcc tagaaaacta gatgaaaata aaaaattatg gtacaatagc
    28741 ttataatatt gtagccgatg gagaaagaca tgaatcttaa acgtgaacaa gaatttgtta
    28801 gtcagtatca ttttgatgca cgtaattttg aatgggaaaa tgaaaatgga gctcctgaaa
    28861 ccaaggtgga tgtgaatttc caattgctcc aacatgacca agaaaatcaa gtgacttcct
    28921 tgattgtcat tttgagcttt atgattgtat ttgataagtt tgtcattagt ggaacaatct
    28981 cacaagtaaa ccatatcgat ggccgtattg tcaatgaacc aagtgaattg aaccaagaag
    29041 aggtggaaac cttggctcgt ccatgtttga acatgctcaa tcgtttgact tacgaagtga
    29101 ctgaaattgc attagactta ccaggaatta atttggagtt ctaatatgaa attagctgtt
    29161 ttcacagatt cctctgctta tctcagtgaa gagaccttgc aaagagaaga cttgtttgtc
    29221 ttggatattc ctgtcaatat tgatggtgag gaatatgtcg aaggcatcaa tctgtctgct
    29281 gaggaatttt accaaaaaat ggctcaggct tctgaattgc ctaagaccag tcaaccaagt
    29341 attgccaagt tagatgagat cttaacttcg ctcaaagaac aaggctatac acatgccttg
    29401 gggcttttcc tatcttctgg aatttcaggt ttttaccaaa atatccagta tatggtcgat
    29461 gactatgagg gcttaaccat tgctttccca gacactttga ttacaagtgc tcccctaggc
    29521 atcatggttg aaagcgtctt taattggcgt gatcagggcg atgattttgc cagcattcag
    29581 gataagctag ccattcaaat cagccgtacg tcagccttta tcatggtaga tgacttggat
    29641 catttggtaa aaggtggacg cctttcaaat ggggctgcca ttttgggcaa tttgcttagc
    29701 attaagccaa tcctttattt taacgatcaa ggtgtgattg aagtttacga aaaagttcgt
    29761 actgaaaaga aggccaccaa gcgcttaatt gaaattatca aggaaacaac ggcttcaggt
    29821 caataccggg tcattgtcat tcatgggaat gctcctgaaa aggctgaaga attgcgtcag
    29881 cacttgcttg attttggctt gggttcggat gtttcacttg ctacatttgg tagtgtcatt
    29941 ggaacgcacc taggagcagg aagtattgct ctgggttata ttccagtgat ttagttggcg
    30001 cttctaggct agttaagatg ccttgtatct tagaaattga acacggacta cctgcctctt
    30061 gaaaaaagat gcctgtcttg cctttcgtgg aaagtcagtg ccattcccta tttttcagag
    30121 gcagctaagg tcctttgtat cttgataatt gaacacgcct ggaaccctgt gtgaaaaaga
    30181 tagttcttcc aagaagtaga cacttcttga ttggaattcc tattttcact ttgtgttctt
    30241 acggactttg tatcttagac aggagtagag atgagtattc gagtaattat tgccggtttt
    30301 aagggaaaga tgggccaggc tgcttgtcag atggtattga ctgatccaga cttggacttg
    30361 gtggcagttt tggatccttt tgagtctgag tcagaatggc agggtattcc tgttttcaag
    30421 gataaggctg atttagctgg ttttgaagcg gatgtctggg tagattttac tactccagct
    30481 gttgcctacg aaaatacacg ttttgctctt gaaaatggct ttgctccagt agttggaacg
    30541 actggtttca cgagtgaaga aattgcagag ctaaaagaat tttctcgtgc ccaagacttg
    30601 ggtggcctga ttgcccctaa ctttgccttg ggtgctgtct tactcatgca atttgcgacg
    30661 caggctgcca aatatttccc aaatgtggag attattgagc tccatcatga caagaaaaag
    30721 gatgctccga gtggaacagc cattaaaaca gctgagttga tggcagaggt tcgagagtcc
    30781 attcagcaag gcgcagcaga tgaggaagag ctgattgctg gtgctcgtgg tgctgacttt
    30841 gatgatatgc gcatccactc agttcgtttg ccaggcttgg tagctcatca ggaagtcatc
    30901 tttggcaatc agggagaagg gttgaccctc cgtcatgact cctatgatcg catctccttc
    30961 atgacaggag tcaatttggg aattaaagaa gttgtcaagc gtcatgagct tgtctatgga
    31021 ttagaacact tattatgaga ttaacgcaaa tgccttctga atttcagaag gctttaccag
    31081 tattagaaaa aattaaagaa gcaggctttg aggcttattt tgttgggggc tctgttcgag
    31141 atgcccttct ccatagccct atccacgatg tggatattgc gacgtcttct tatccagaag
    31201 agaccaagca gatttttccg cgaacagccg atatcggaat cgagcatgga accgtcttgg
    31261 tcttagatgg ggatgaggag tatgaggtaa caacctttcg gacagaggat gtctatgtgg
    31321 actatcgcag acccagtgcg gtttcctttg tacgatcgct agaagaagac ctcaaacgcc
    31381 gtgatttcac agtcaacgcc tttgccttgg atgagacagg agaaatcgtt gacttgttcc
    31441 atggtttaga agatttggaa aagcaagtct tgcgagcagt tggagtggct agtgagcgtt
    31501 tcaacgaaga tgctttacgg attatgcgtg gtttccgttt tcaggctagt cttggttttg
    31561 cacttgagcc agaaacattt aaagctatga agaccttgac gccgcttttg gagaaaattt
    31621 ctgtagagcg taccttcgtc gagtttgata aactcttgct ggctccattt tggagaaggg
    31681 gcttggcttc catgattgag agtcaagctt atgactatct ccctgatatg gcatctagcc
    31741 aggacaagct caacagactg tttgatttgg agactgattt tacttttgaa tcctctgaac
    31801 aagcctgggc ggctttacta tgggctttgg agattgaaaa tgcgcagtca tttttgaaat
    31861 cttggaagac ctcacgccag tttgccaagc aagttcagga tttgctgatt attttggctc
    31921 tgcgtgaaaa tggagaattg agtaagcgag attgttatcg ctttgacata gatttgcttt
    31981 tacaggctga aaatcttcgt caagctcaag gaaaagaagt caacccacaa gccatcacag
    32041 aaaaatacca aagcttgact atccatgaca agaaagagat tcagattaat ggcgatattt
    32101 tgatcaagga atatggctat cagccaggcc cagacttggg agagatttta acagagattg
    32161 agtttgccat tgtcgatgga gaattggaga ataatcgtga agccatccat gcttacctga
    32221 gggagaaaaa atgagtgatt ttatcgttga aaaactaagt aaatccgttg gtgacaagac
    32281 cgtttttagg gatatttcct ttattatcca tgacttagac agaattggtt taatcggtgt
    32341 caatgggact ggcaagacca cccttttgga cgtcctttct ggtgtttctg gatttgatgg
    32401 ggatgtcagt cctttttcag ctaaaaatga ttaccagatt ggttacttga ctcaggatcc
    32461 tgattttgat gatagaaaga cagttttgga tacggttcta tctagtgaac tcaaggaaat
    32521 ccagctcatt cgtgagtatg aattgattat gctcgactat agtgaggaca agcaggcgcg
    32581 tttggaacgt gtcatggcag agatggactc tctccaagct tgggaaatcg aaagtcaggt
    32641 caagaccgtt cttagcaaat tgggcattca agacttatct actcctgttg gggaattgtc
    32701 aggtggtctg agaagacggg tacagttggc acaagtctta cttggcaacc acgacctctt
    32761 gcttttggat gagccgacca accatctgga tattgcgatt attgagtggc tgaccctctt
    32821 tttgaaaaat tctaagaaga ccgtcctttt tatcactcac gatcgttatt tcttagacgc
    32881 tttgtcaaca cggattttcg agttggatcg tgcaggcttg accgagtacc agggcaatta
    32941 ccaggactat gttcgcctaa aggcggaaca ggatgagcgc gacgcggctc ttcttcacaa
    33001 aaaagaacaa ctctacaaac aagaactggc ctggatgcgc agacaaccgc aggcgcgtgc
    33061 gaccaagcag caggcccgta tcaatcgatt ccatgatctg aaaaaggaag tttcaggcag
    33121 tagtgctgag acagacttga ccatgaactt tgaaaccagt cggattggga agaaagtcat
    33181 cgagtttcag gctgtttcct ttgcctatga aaacaagcct attttgcaag attttaatct
    33241 cttggtgcag gccaaagacc gtatcggaat cgttggggac aatggtgttg gaaaatcaac
    33301 cctgctcaac ttgattgcag gaagtcttga gccaactaaa ggacaagttg tgattgggga
    33361 aactgttcgc atcgcctatt tctctcagca aattgagggt ttggatgaaa gcaagagagt
    33421 tatcaattac ctgcaggaag tggcagaaga ggtcaagacc agtggcggtt ctacgacttc
    33481 gattgcagag ttgctggagc agttcctttt cccacgttcg acgcatggaa ccttgattga
    33541 gaaattgtca gggggtgaga aaaaacgtct ttatctcctc aaactgcttt tggaaaaacc
    33601 aaatgttctt cttttagacg agccaaccaa tgacctagat attgcaactt tgacagtctt
    33661 agagaatttc ttgcaaggtt ttgcaggtcc cgttttaaca gtcagtcacg accgctattt
    33721 cttggataag gtagcgacca agattctcgc ttttgaggat agcaagattc gtcctttctt
    33781 tggtcattac accgactatc ttgatgaaaa agcttttgaa acagatatgg ccaatcaagt
    33841 gcaaaaggtc gaaaaggaaa aagtggtcaa ggttcgagaa gacaagaaac gtatgaccta
    33901 ccaagaaaag caggagtggg caagtattga aggtgatatt gaaaccttgg aaaaacgtat
    33961 cgctgctatt gaagaggaaa tgcaggctaa cggctctgac tttggtaagc tggctactct
    34021 ccaaaaagaa ttggatgaga aaaatgaagc actccttgaa aaatacgaac gctatgagta
    34081 tctcagtgaa tttgatagtt aagactattc gaaaatcaaa gtgcaaacta tgtcggcttc
    34141 acattgccga ctcaagtaca gcctgtgacc ggcttcctaa tttgcacttt gatttttatt
    34201 gagtataaaa gaatagaaaa atcccgtctc atgaaaggat ttctctattc ttttttggtt
    34261 tcttgatgaa agatattttg ccaggtttcg tggcgacgcc agatactggt atggatgata
    34321 ccatctaact catagcagat gagtttggtt ttttgactga tggaagtaat ttgaatgtcc
    34381 ttgatagcag aatttaactc ttttttggtc ttataagcct ctttatccat ctgctctcca
    34441 tcttggcgaa tatagacaaa atcatcagtc aagagttctt ctagttggtt tccttggtca
    34501 atcaattgtt cacgcataag caatttttta tagacattgt ctaaaatttc atcctcagag
    34561 ataggtgctg gttcgatatg gacatcggta tcaaagacgc caaaacgctc ctccagcata
    34621 gactcgacct gatccgcgat ttcatggctt tcaaaaacag acaagtcagg attcatctct
    34681 agtgtaatat ccaggtagat gttgctaccg taggtgcgac ctctttgcga tttgaccttg
    34741 ctgattttgg gaatttccat gatagccttt tggtagtcct cgagcaggcg gtcgtcaaag
    34801 ccatctgaaa gactaaagga agactcgatg aagatatcat aggcagtctt caagataaag
    34861 aaagtgatga tgatagcaac cagtttatcc acaatcggat aattgaaact actagctagg
    34921 atggcaatgg cggttccaag tgaggtaaca gcgtcagaaa gattgtcctt agcagctgcc
    34981 ttcagcgcct tggagttgga tttcttactg aggcgagtat tgtagagata gaccacaaac
    35041 ataatcgctg cagaaatgat tcctagagtt gcaccaagag gatcaatgac cgtttcttcc
    35101 cgactgagaa tcttttgaat ggtatctctt agaacatcga aaccgacata gaacatgatg
    35161 atagaagtga tcaagcttgc caaatcttca atcttccaat gaccaaaacg gtggtcacgg
    35221 tctgcaggct ggcgcgccat ccgaatcccg attaagaggg ccacatttcc aatgatgtcc
    35281 gatacgttat taaaaccatc ggccaccaaa ctggatgaat gaaggagatg accagctgct
    35341 aatttggctg cagacaagat caaataggtc gaaatactga taatggctcc acgctcagct
    35401 aacttgagat ttgagataga ttgcttcatt caacttcctt tctagtcaca tagcattcta
    35461 ccattatact ggttttcaag gaaaaattca aataaggcag tttttactct ttgaaaactc
    35521 cccaaaattt ggtataatgg tactactcaa gggagtagct ggcagaaacc tgtgatagtg
    35581 tcgtcattcc gaattttatg ctgaaaagta tgctttccgg ccctatctta aacagcgaga
    35641 cttgttatga ttaacaggtc tctttttgtt tgtcgtgaaa agatatgaca gaaagagagt
    35701 ctgttttgca cacaatgtca aggaggagac acatgtcaaa agaacaaaaa cgccaagcgt
    35761 tttatactca gagccctgaa gaggtcttgc aggctgtgga tgcgaccgag caaggtttgt
    35821 catcaagtga ggcggaaaag cgccttgctg aatttgggca caatgaactc gaagaaggcg
    35881 agaaacgatc aatcttggtc aaattcatcg agcaatttaa ggatttgatg attatcatcc
    35941 tagttgcggc agcaatcttg tcagtcgtga cttctggtgg ggaagatatc gcagatgcca
    36001 ttatcatcct agctgtggtt atcatcaacg ctgcctttgg tgtttaccaa gaaggaaaag
    36061 ctgaagaagc tattgaagcc ctcaaatcca tgtctagtcc agttgcccgc gttcttcgtg
    36121 atggacacat ggcagagatt gactctaaag aattggtacc aggcgatatc gttgcccttg
    36181 aagcaggtga cgtggtacca gcggacctac gtttgataga agccaactct cttaaaattg
    36241 aagaagcagc cttgacaggt gaatctgtac cagtcgaaaa agacttgtca gtcgagcttg
    36301 cgacagatgc tggtattggt gaccgtgtca acatggcctt ccaaaactca aacgtaacct
    36361 atggtcgtgg gatgggtgtt gttgtcaata caggtatgta cactgaagtt ggtcatattg
    36421 ctggtatgct tcaagatgcg gatgagactg atacaccact caaacaaaat ttgaacaacc
    36481 tttctaaggt cttgacctat gctatcttgg tcattgccct tgttactttt gtagtgggtg
    36541 tcttcattca agggaaaaat ccacttggtg agttgttgac ttctgttgcc cttgccgttg
    36601 cagccattcc agaaggactt cctgctatcg ttaccatcgt tctttctctt ggtactcaag
    36661 ttttggccaa acgacattcc atcgttcgta agttgccagc agttgaaaca cttggttcaa
    36721 ctgaaatcat cgcttctgat aagactggta cgctgactat gaacaagatg acagtcgaaa
    36781 aagtcttcta cgatgcggtt ctacatgact cagctgatga tattgaacta ggtcttgaaa
    36841 tgccactact tcgttcagtt gtcttggcca atgatacgaa aatcgatgtg gaaggtaact
    36901 tgattggtga cccaaccgaa acagccttta tccaatatgc cttggacaag ggctatgatg
    36961 tcaaaggttt cttagagaaa tatcctcgtg tagctgaatt gccatttgac tctgaccgta
    37021 agctcatgtc aacagttcac ccattgccag atggtcgttt ccttgtagca gtcaagggtg
    37081 cgccagacca actcttaaaa cgttgtcttc ttcgtgataa ggctggggat attgctccga
    37141 ttgatgagaa ggttacaaat ctcattcata caaacaattc tgaaatggct catcaagcct
    37201 tgcgtgtcct tgcaggtgct tataagatta tcgatagtat tccagaaaat ctcacttctg
    37261 aagagcttga aaatgattta atttttactg gtttgattgg gatgattgac cctgaacgtc
    37321 ctgaagccgc tgaggctgtt cgtgtggcta aggaagcggg aatccgtcca attatgatta
    37381 caggtgacca ccaagacaca gcggaagcca ttgccaaacg tttgggaatc attgacgcaa
    37441 acgatacaga aggtcacgtt ttaactggtg ctgaactcaa tgaactgtca gatgaagaat
    37501 ttgaaaaagt cgttggtcaa tactctgttt atgcccgtgt gtctccagaa cacaaggttc
    37561 gtatcgtcaa ggcttggcaa aaacaaggta aagtcgttgc catgacaggt gacggtgtca
    37621 atgacgcgcc agctctgaaa acagccgata tcggtatcgg tatgggaatc actggtacag
    37681 aggtttctaa gggggcttct gatatgattc ttgcagatga taactttgcg actattatcg
    37741 tcgcagtgga agaaggacgt aaggtcttct caaacattca aaagactatt cagtacctac
    37801 tttctgctaa tactgctgaa gtattaacca tcttcctatc aaccttgttt ggttgggatg
    37861 tcttacagcc ggttcatctt ttgtggatta acttggtaac ggataccttc ccagctatcg
    37921 ctcttggtgt tgaacctgcg gaacctggtg tcatgaatca taaaccacgt ggacgcaagg
    37981 caagcttctt ctcaggtggt gttttgagtt ctatcattta tcaaggtgta ctccaagcag
    38041 ctcttgttat gagtgtttat ggccttgcga ttgcttaccc agttcatgtg ggtgacaatc
    38101 atgctattca tgcagatgcc ctaacgatgg cctttgcaac ccttggtttg attcagctct
    38161 tccatgccta caatgtcaag tctgtctacc aatccatctt gacagttggc ccattcaagt
    38221 ctaagacctt taactggtcc atcttggtat cctttatcct tctcatggca acaatcgttg
    38281 tagaaccgct tgaaggaatc ttccacgtaa ccaaactaga cttgtcacaa tggggaattg
    38341 ttatggctgg aagcttctca atgattatca tcgtcgaaat cgttaagttt attcaacgca
    38401 aactcggttt tgacaagaat gcgatttaag ggaggtttcg gatgtcagca tatcaattac
    38461 cgaccgtatg gcaggatgaa gctagtaatc aaggagcttt tacggggcta aacagaccaa
    38521 cagcaggtgc ccgtttcgaa caaaacttgc caaaaggaga acaagctttt cagctttatt
    38581 cactgggaac accaaatggt gtgaaggtta ctatcttatt ggaagaatta ctagaagctg
    38641 gttttaagga agcggcttac gacttgtata agattgctat catggatggg gatcaattcg
    38701 gctcagactt tgtgaagctc aatccaaatt ccaagattcc agccttattg gaccagtcag
    38761 gtactgaaaa cgtaagagtc tttgagtctg ctcatattct tctttacctt gctgagaaat
    38821 ttggagcctt tttaccaagt aatcctgtgg aaaaggtaga agttttgaat tggctattct
    38881 ggcaagcagg tgcagcacct tttctaggtg ggggatttgg acatttcttc aattatgctc
    38941 ctgaaaaatt ggaatatcct attaaccgtt ttacgatgga agtgaaacgc cagttggatt
    39001 tattggataa ggaattggct cagaaacctt atattgcagg caatgactat acgattgcag
    39061 atattgctat ctggtcttgg tatggacagt tagttcaagg aaatctttac caaggttctg
    39121 caaaattctt ggatgcctca agttatcaaa atctagtaaa atgggcagaa aaaattgcca
    39181 atcgtccagc tgttaagcgt ggcttggaag taacttatac agaaattaaa tagcaaaaaa
    39241 gtcatcttcg gatggctttt tgctacagtt gagggaaagg gtttgcagtt atcggctttt
    39301 gtgctataat tgctataata tagtaaaaag caagaggagt gtgaggaagt ggaaaagaaa
    39361 attgtgaagg atatcttatt tttatctcaa gtgtctcatc cggcaagtca ggaggacctt
    39421 tatcttgcca gagatttgca ggatacactc ttagcaaatc gtgatacctg tgttggtcta
    39481 gctgccaata tgattgggat gcagaagcgc gtgattatct ttaatcttgg cttggttccc
    39541 gtggtcatgt ttaacccagt gcttctgtcc tttgaaggat cctatgaggc agaagaaggc
    39601 tgtttgtcct tggtaggtgt gagatcaact aagcgttatg aaaccataag gcttgcctat
    39661 cgtgacagca agtggcagga acagaccatt accttgacag gcttcccagc tcagatttgc
    39721 cagcatgagc tggatcactt ggaaggacga atcatttagg aggaaagcaa atgaaacgaa
    39781 tagtctttga acttattttt atcgcaacga cctggtatat ctttttaccg ccccttaacc
    39841 tgaccagctg ggaatttctc ttcttcctct gtgggcattt gttagttgtg gcaatcttat
    39901 ttggctttgg caaggggata aaccttgtca aaacggttca tgtgcgccac ggtaaggcgg
    39961 aagctgcctt aaatcttgag ggtttcaaaa tcaatcggtt agggaaaatt ctgttagctt
    40021 cgattggagg aattcttctc ttggcagctt tggtttcctt ggtaacttct agcatgtttc
    40081 aggctaaaaa ttatgccaat gtagtcacgg ttacggaaaa agactttact gaatttccta
    40141 agagtgacac cagtaaggtt cctatcctag atagaagtac tgctgaaaaa attggagacc
    40201 gctacttggg ttccctaacc gataaggtgt cgcaatacgt agcggcagat acctataccc
    40261 aattgacaat tgatgggaaa ccttatcggg tcacaccact agaatatgca gaccctatca
    40321 aatggtttaa caatcaagcc aagggaatcg gtgagtatat caaggtggac atggtaactg
    40381 gaaatgcgga tttggtggac ttgaagacac caatcaagta ttcagactcg gagtatttta
    40441 accgtgatgt caaacgtcac ctgcgcttga agtacccgac caaaatcttt aaaactccat
    40501 cttttgaggt ggacgatgag ggcaatcctt tctatgtagc aacggtttac caaaagcaat
    40561 ttggacttgc tgttcctcgt cctgcttcag tcattatctt ggatgctaca aatggagaaa
    40621 ccaaggaata cagcttatca gatgttccag aatgggtgga caggatctat ccagcagagg
    40681 aaaccattga gcaaatcaac tacaacggca agtacaagga cggtttcttg aatgccatga
    40741 tttccaagaa aaacgtgacc cagacgacca atggctataa ttacttgtct atcggtaatg
    40801 acatctatct ctacacaggt gtgacgtcgg ctaatgcgga tgagagtaat cttggtttca
    40861 tccttgaaaa tatgcgaaca ggagaaatta ctaagtatag cttggcttct gcgacagaag
    40921 aatcagcccg tgaatcagca gaaggtgctg ttcaggagaa atcctacaaa gcaaccttcc
    40981 caatcctcat caacctcaat gacaagcctc tctacatcat gggcttaaag gacaatgctg
    41041 gcttggtcaa agagtacgcc ctggtagacg cagtcgagta ccaaaatgtt atcgttgcta
    41101 ctacagtgga agagatgctc agcaagtatg ccaataaaaa cgaccttgaa attgacaatg
    41161 caacgacaga aagcatcaag ggagtagtag cagacctcaa atcagctgtt atcaagggag
    41221 acactgtcta cttctttaaa gttgatggca agatatacaa ggtaaaggct tcagtatccg
    41281 atgaccttcc ttaccttgaa aatggtaaaa ccttcgaagg tcaagtagga aaagacaatt
    41341 atctcaagac ctttaaagta caataatact cttcgaaaat ctctagctct atctgcaacc
    41401 tcaaaacagt gttttgagca gcctgcggct agtttcctag tttgctcttt gattttcatt
    41461 gagtataaaa aaggtttatt taataaatat atgttataat aaggtaaatt aagcctaatg
    41521 gaggacaaag aaatgggttt ttatttgatg gttgcttcaa tgctactcgg actgctcgct
    41581 ttgaagatag gtttttctca gttcaaggag aaaaaagata aattcttatc tatcttaaca
    41641 agtttagctg gcacagccct tgttctcgtg gctgtctggt taggatggcc caaataaata
    41701 gaaaaacctc ggtcaaaccg aggtttttca aatgaatttc ttggttgtgg ctaaaaaata
    41761 tgctacacta tcaatatgaa aattttaatc ccaacagcaa aagaaatgaa cacagacttg
    41821 ccaagtatcg aggcaattcc tttaaaacca gaaagtcaga ccgtgcttga tgccttggct
    41881 ctctattctg ccagtcaatt ggagagtttc tacaaggtat cagctgagaa agcggcggaa
    41941 gaatttcaaa atatccaagc tttgaaaagg caaactgctc aacactatcc agccttgaaa
    42001 ctttttgatg ggcttatgta ccgcaacatt aagagagata agctgaccga ggcggaacaa
    42061 gattatcttg aaaatcatgt cttcattacc tcggctttgt acggtgttgt tccagccttg
    42121 tcacccatgg ctcctcaccg tttggatttt ttgatgaaat taaaagtcgc tggtaagact
    42181 ttgaagagcc attggaaggc agtctatgat gaagctctga agaaggaaga agtgattttc
    42241 tctctcttgt catcagagtt tgagactgta ttttctaagg aaatcagagc aaagatggtg
    42301 accttcaaat tcatggagga tagaggcggt cagctgaaga ttcactcaac tatctccaag
    42361 aaagcgcgcg gggcctttct aacagcttta atagaaaatc aagtacaaac tgtgggggaa
    42421 gcacgtcgct tgaactttgc tggatttgtt taccgagaag atttgtcaca accacaggga
    42481 ttggtttttg taaaggaagt atagaaatca gataagagaa aagtcagcac gattatgctg
    42541 acttttttga taacttataa agtattggac aaatgaatct catttgataa ggtgttaaga
    42601 tgattaacca aattcatgat tgacagatga tttcggcaaa taaacttctt ggtaatccct
    42661 gaaatataga aattagacac gatgatatcg taatctgtct gatttaaaat ctcaggactt
    42721 gtttttaatt catcccaaat atcgaaggta aagcggttat tacagtaata ggaaagcata
    42781 tcaacaaagg taagggatat agcatggtca aagttactga taatcaaaac cttgataggt
    42841 ggtcgatttt ctaacaactg agtagagagg ttttcagcat gggttaagat ggtgtacatc
    42901 aagtgttcca actgttcagg atggtcatgc tgtccaattg cctgacggta ttgagccagt
    42961 tcttgacgcg cacttcccat aaagtctggg aagtaacctt caaatttttt aatcgtcaat
    43021 gctttttgtt caaataagat tggggtagaa aagatttcct gtctttcaaa gaaagcagtg
    43081 ttgtgtaaat gccaaatcag ctcatcgtgg ttagtaaaag taatcttata ttgttttgat
    43141 aggcgttcta atatttgact aagtaattgg taagagtatc ttgcttgact gttatcttct
    43201 aaagagttga agaattcttg aggatctagg aaaatatcat tctgaagaaa agaaataaaa
    43261 atttgagcga ttgtatctgg agtcatttca agcccaaaat gtttagagaa ataagcaagt
    43321 gtctcctgga aatttggaat gctctttaaa agaggataat attctttgta aaagtggttg
    43381 gggaggtcaa tgaagtgacc atttttaacc ctgtggatac tgatagctat catcagtttg
    43441 tacattctat aaattgaaaa tcgcattgga taattcgtga ttttatagaa gaagtcagca
    43501 aactctgtta aatcttcctc aggaaggtca ggaaaaggcc aatctaggaa ataatagcgc
    43561 tcagaaaagt attgggcaaa aaagtaacga atatcgatct catttccacg tatctcggat
    43621 ggagtaaaag ataattcaat ttgaaactga gatgaaagaa cctttgtaat atttctgccc
    43681 agtcgataga ggttggcact actaaagtaa agattttcta ttgttcgata aataggtagc
    43741 ccctcattga agaacatata ctctagtaat tgaaaagatt gagaattagc aagaaaatat
    43801 tgataaatat cttctacact agtgttaact tctaaatcta tcatgattcc gttaacagaa
    43861 gattggatgt taatagatgg aaaggcaata cgtaattcat ttaaatcact ttttaagatt
    43921 cgttctgtac atcctaattt ttcggctagt tcatgtaatt tcatccaatt acgattctga
    43981 attagggttt ccattaagcg taattgtctt tgaacttttg tggataaaag gtttctcata
    44041 cgggtatttc ctccataatt cattatatct ttttttgtct aagtagtata aaaaaattag
    44101 agcaagaaaa ttgtcgttag taatcggaaa aattagaata atataagtgg cttttaagtg
    44161 caaaaacaga atatattaat tgttcagaaa atattgatta atgcctcaaa tagttgtaca
    44221 ttgtaaacta taaaatacta tctaggagtt taaaatgaaa cattcacata aaaaatcatt
    44281 tgactggtat agcatgcaac aacgttattc tattcgtaag tattactttg gtgcagttag
    44341 tgtcttgctc ggtaccgctt tggtattagg tgcagcagct agtgtccaaa cagtacaagc
    44401 ggaagaaaac aaacaagaaa ctaccaatag tatttctgtt ggtaggggag aagcagctac
    44461 taaaccagca gaggtttctg cgtctaataa agagaaaacc tatgcagctc caactgtagc
    44521 taatccagta gaaacgactc cagttaaaac tggagaagtt actaaaccag cagaaaaagt
    44581 tgaagaagca aaagacaaaa aagaggaagt aacgcatcaa gatgctattg acaagtcaaa
    44641 attgttaacg gctctttcgc gtgctaaaaa gttagaaagc aagttatata cagaagcaag
    44701 tgctgctaac ttgcaaacaa gtatccaagc tggtcaaagc ttgcttggga aagcagatgc
    44761 atctgaagct gaattatcag cagcagagtc atctattcaa tcatctatta ttggtctaga
    44821 acttcgttct aactctaaca aaggaactgt atcagaaact cctgtagcga agaaagctaa
    44881 tatagttgaa gcgaaggaag agactaatcc agctgcaaca actgatcgtt cagctgttga
    44941 tagtgctgtt ttgccaacta gcacagctgc caaagtagaa acaacttcag ctccagcatc
    45001 tattaatgaa atcttgaaac caggtttgag cctttctgat gctcgccaaa atccagctat
    45061 ccgtaaggaa gatgttgata gagggtatag tggttttaga gcggcgcctg ctccaacgaa
    45121 ccaaccagta actaatctag gaaataatac tgttttcact gatattagca gaggttctca
    45181 tactttccgt ggtaatggaa attcacgtcg tggaaacccg attcattttg atgtaacaac
    45241 aactagagtt agaaatagag tagatttctc aatcagatat tcaggaccag gtgagtttgt
    45301 taataacaac tttatcttag acaaaggaaa tggattcgga gaaccttctc gtgcaactgt
    45361 ttcaacacca aaattaagag accaagttaa aaacattagt aagggtggaa actttgtttc
    45421 tcattcaggc tacagtttag aagctgcagt agaaacaagc accaatcaaa caattaagtt
    45481 tagtttacct atagccaacc ctaatggtga tctgtctgtt cgattaagac ctgttacttt
    45541 taatgtaggt caaggggaat caggatctgc aactagtaat gatccatata gtaactctaa
    45601 ctattacttc agagaaaaac cactcctctt ggatgcaaat ccaaatggtg gtactaataa
    45661 taagactgtt tcagaagaca ttgacttcca aactgtctat cttccaacta gtaagttacc
    45721 agaaggtcaa actagattag ttcgagaagg tgaaaaagga caacgtcaaa tcatctataa
    45781 agttcatcaa ttgggtaacg aaacaatcct aggattgcca attagtaatt cagttattaa
    45841 agaagttaag ccacgtatta tgcaaattgg tgtggctaaa gatctaatcg atacagtaaa
    45901 accacgtgtt gatcaaaata aagtcggtga tacaaataac ctcactttct atcttgataa
    45961 cgatggaaac ggtgtttata ctgagggcgt agacgaactt gttcaaaaaa ttgctattaa
    46021 agatggtgct aaaggtgaaa aaggagcccg aggcgaacgc ggtctaactg gagctcaagg
    46081 agctaaaggt gaaaaaggag accgaggtga acgcggtcta actggagctc aaggagctaa
    46141 aggtgaaaaa ggagaccgag gtgaacgcgg tctaaccgga gctcaaggag ctaaaggtga
    46201 aaaaggagac c
//
LOCUS       DAVBIC010000009        45892 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.009, whole genome shotgun sequence.
ACCESSION   DAVBIC010000009 DAVBIC010000000
VERSION     DAVBIC010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 45892)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45892)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45892
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.009"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            <1..1194
                     /locus_tag="VQ664_000485"
     CDS             <1..1194
                     /locus_tag="VQ664_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HET2788711.1"
                     /translation="STSASESASTSASASASTSASASASTSASASASTSASESASTSA
                     STSASASASTSASASASTSASTSTSTSASTSASTSASTSASTSASTSASESASTSAST
                     SASTSASASASISASESASTSASASASTSASASASTSASESASTSASASASTSTSASE
                     SASTSASASASTSASASASTSASASASTSASESASTSTSASESASTSASASASTSASA
                     SASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASA
                     STSASASASTSASASASTSASASASTSASASASTSASESASTSASESASTSASASAST
                     SVSNSANHSNSQVGNASGSTGKSQKELPNTGTESSIGSVLLGVLAAVTGIGLVAKRRK
                     RDEEE"
     gene            1255..3340
                     /locus_tag="VQ664_000486"
                     /pseudo
     CDS             1255..3340
                     /locus_tag="VQ664_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000341103.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
     gene            3337..4215
                     /locus_tag="VQ664_000487"
     CDS             3337..4215
                     /locus_tag="VQ664_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exopolysaccharide biosynthesis protein"
                     /protein_id="HET2788712.1"
                     /translation="MKKNHLVGDALILTVSDQIEELDYLLESLPNICFYIAAPVQFSE
                     KIRSLETNYNVRLRTITNEEQLNFLVDTCDFLLDINHFQEVDAIVSKFVQAGKSVFAF
                     DNTVHGNQGQEVFLSSTPDKLVSRVRDYLNEVRVGTNHQEKIIQDGTWNVFKIDDKAH
                     FIVGANVICRNFENFHVSSGKLILHDGVFINNSCSFNCMERIEIGAGTMMGEGVRFYD
                     HDHIYTAEKIEKWQWTTAPIRVGRDCWIGSNVTILKGVTIGDNTIIGAGCLIRNDIPS
                     NSVVYNNGNLVVKRRD"
     gene            4255..4533
                     /locus_tag="VQ664_000488"
     CDS             4255..4533
                     /locus_tag="VQ664_000488"
                     /inference="COORDINATES: protein motif:HMM:NF021616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET2788713.1"
                     /translation="MENELISIVVPIYNVENYLRQCLDSIQKQTYPNFECIMVNDGSP
                     DHSSKICEEFVEKDSRFKYFEKANGGLSSARNLGIECSGGGVHYFCRL"
     gene            4541..5131
                     /locus_tag="VQ664_000489"
     CDS             4541..5131
                     /locus_tag="VQ664_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HET2788714.1"
                     /translation="MEHDALDRLYGALKKENADISIGRYNSYDETRYVYMTYVTDPDD
                     SLEVIEGKAIMDREGVEEVRNGNWTVAVLKLFKRELLQDLPFPIGKIAEDTYWTWKVL
                     LRASRIVYLNRCVYWYRVGLSDTLSNTWSEKRMYDEIGAREEKIAILASSDYDLTNHI
                     LIYKNRLQRVIAKLEEQNMQFTEIYRRMMEKLSLLP"
     gene            5160..6170
                     /locus_tag="VQ664_000490"
     CDS             5160..6170
                     /locus_tag="VQ664_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HET2788715.1"
                     /translation="MKLHLTNLYGMAGDSTVILAQNAVQKIASQLGFREVGIYFYNIA
                     SDSPSEMNKRLDGIMASISIGDILVFQSPTWNGFEFDRLLFDKLKDMQVKIICFIHDV
                     VPLMFDSNYYLMKDYMYMYNLSDVLIVPSERMKTRLMEEGLTTKKILVQGMWDHPHDL
                     SLYTPAFKKELFFAGSLERFPDLQNWSQDTPLRVFSNKGEASSSARNLSIEGWKKDEE
                     LLLELSKGGFGLVWGTYQNDGESNQYYTLNISHKVSTYLTAGIPVIVPSSLSTAKFIV
                     DQGLGFVANSLEEVHAIVDKMNLQEYQEMTNRIKTFSYLLKEGYFTKKLLVDAIYHLG
                     VE"
     gene            6180..8624
                     /locus_tag="VQ664_000491"
     CDS             6180..8624
                     /locus_tag="VQ664_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_1767 family glycosyltransferase"
                     /protein_id="HET2788716.1"
                     /translation="MIKTIVLAGDRNYIRQLETTIKSILYHNRDVKIYILNQDIMPDW
                     FRKPRKIARMLGSEIIDVKLPEQTVFQDWEKQDHISSITYTRYFIADYIQEDKVLYLD
                     SDLIVNTSLEKLFSICLEEKSLAAVKDTDGITFNAGVLLINNKKWRQEKLKERLIEQS
                     IVTMKEVEEGRFEHFNGDQTIFNQVLQDDWLELDKEFNLQVGHDVTAFYNKWENYFNE
                     LVPPSIIHFVSYRKPWTTLIANRYRDLWWEFHDLEWTKILQHHIGEFELTSSLDKEFS
                     CLTLTNSQDLEGIEELVTALPDVVFHIAAWTDMGDKLIKLAVYDNVRLHPQIVPPVLD
                     KLKKSTNLYLDINHGSADENFLKSLQEQEKTLLAFQSTQHGELGQIVFENGKVSFMID
                     TIKDFKKNGHLTCFRQLPSLTCLTFTASQDIEQLDYLAGQLPNVVFQVAAWTAMGPKL
                     YDLSNRYPNIQLYPAISRDKLDELKEKMDAYLDINLLTSTSDIVAEMAHLSKPILAFY
                     KSQNGNNGQRLYSSEHPERMLADLQKLITKDMLEKPLDIIQVKGIDETLDYIIEHNSS
                     LVRFGDGEINMLAGHSIPYQDYDEELVSIMRDIIGQESREDLVVCLPDAFTDRFRFTS
                     WAIPFWKDHMDHYMDFYRELCSDSWYGSTFVSRPYIDFEDKSQAKAQFEKLKSIWENR
                     DLLIVEGATSRSGVGNDLFDEANSIKRIICPSHSAFSRVHEIEQEIEKYAGGRLILCM
                     LGPTAKVLSYNLCQMGYQVLDVGHIDSEYEWMKMGAKTKVKFSHKHTAEYNFDQDIEF
                     IDDETYNSQIVARILN"
     gene            8655..9875
                     /locus_tag="VQ664_000492"
     CDS             8655..9875
                     /locus_tag="VQ664_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 8"
                     /protein_id="HET2788717.1"
                     /translation="MRNTKRAVAFAGDYAYIRQIETAMKSLCRHNSHLKIYLLNQDIP
                     QEWFSQIRIYLQEMGGDLIDCKLIGSQFQMNWSNKLPHINHMTFARYFIPDFVTEDKV
                     LYLDSDLIVTGDLTDLFELDLGENYLAAARSCFGAGVGFNAGVLLINNKKWGSETIRQ
                     KLIDLTEKEHENVEEGDQSILNMLFKDQYSSLEDQYNFQIGYDYGAAAFKHQFIFDIP
                     LEPLPLILHYISQDKPWNQFSVGRLREVWWEYSLMDWSVILNEWFSKSVKYPSKSQIF
                     KLQCVNLTNSWCVEKIDYLAEQLPEVHFHIVAYTNMANELLALTRFPNVTVYPNSLPM
                     LLEQIVIASDLYLDLNHDRKLEDAYEFVLKYKKPMIAFDNTCSENLSEISYEGIYPSS
                     IPKKMVAAIRSYMR"
     gene            9884..11080
                     /locus_tag="VQ664_000493"
     CDS             9884..11080
                     /locus_tag="VQ664_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HET2788718.1"
                     /translation="MRKSIVLAADNAYLIPLETTIKSVLYHNRDVDFYILNSDIAPEW
                     FKLLGRKMEVVNSTIRSVHIDKELFESYKTGPHINYASYFRFFATEVVESDRVLYLDS
                     DIIVTGELATLFEIDLKGYSIGAVDDVYAYEGRKSGFNAGMLLMDVAKWKEHSIVNSL
                     LELAAEQNQVVHLGDQSILNIYFEDNWLALDKTYNYMVGVDIYHLAQECERLDDNPPT
                     IVHYASHDKPWNTYSISRLRELWWVYRDLDWSEIAFQRSDLNYFERSNQSKKQVMLVT
                     WSADIKHLEYLVQRLPDWHFHLAAPCDCSEELTSLSQYTNVTVYQNVLHSRIDWLLDD
                     SIVYLDINTGGEVFNVVTRAQESGKKIFAFDITRKSMDDGLYDGIFSVERPDDLVDRM
                     KNIEIE"
     gene            11080..11322
                     /locus_tag="VQ664_000494"
     CDS             11080..11322
                     /locus_tag="VQ664_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET2788719.1"
                     /translation="MSELISVVVPIYNTGKYLVECVEHILKQTYQNIEIILVDDGSTD
                     NSGEICDAFMMQDNRVRVLHQENKGGQHKLKIWGLV"
     gene            11307..11984
                     /locus_tag="VQ664_000495"
     CDS             11307..11984
                     /locus_tag="VQ664_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HET2788720.1"
                     /translation="MGISVAKGEYITIVDSDDIVKENMIETLYQQVQEKDADVVIGNY
                     YNYDESDGNFYFYVTGQDFCVEELAIQEIMNRQAGDWKFNSSAFILPTFKLIKKELFN
                     EVHFSNGRRFDDEATMHRFYLLASKIVFINDNLYLYRRRSGSIMRTEFDLSWARDIVE
                     VFSKKISDCVLAGLDVSVLRIRFVNLLKDYKQTLEYHQLTDTEEYKDICFRLKLFFDA
                     EQRNGKS"
     gene            12041..13258
                     /gene="secY2"
                     /locus_tag="VQ664_000496"
     CDS             12041..13258
                     /gene="secY2"
                     /locus_tag="VQ664_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein translocase subunit
                     SecY2"
                     /protein_id="HET2788721.1"
                     /translation="MTKIYSSIAVKKGLFTLFLLFIYVLGSRITLPFVDLNTKDFLGG
                     STAYLAFSAALTGGNLRSLSIFSVGLSPWMSAMILWQMFSFSKRLGLTSTSIEIQDRR
                     KMYLTLMIAVIQSLAVSLRLPVQSSYSAILVVLMNTILLIAGTFFLVWLSDLNASMGI
                     GGSIVILLSSMVLNIPQDVLETFQTVHIPTGIIVLLALLTLVFSYLLALMYRARYLVP
                     VNKIGLHNRFKRYFYLEIMLNPAGGMPYMYVMSFLSVPAYLFILLGFIFPNHSGLAAL
                     SKEFMIGKPLWVYVYISVLFLFSIIFAFVTMNGEEIADRMKKSGEYIYGIYPGADTSR
                     FINRLVLRFSVIGGLFNVVMAGGPMLFVLFDEKLLRLAMIPGLFMMFGGMIFTIRDEV
                     KALRLNETYKPLI"
     gene            13268..14848
                     /gene="asp1"
                     /locus_tag="VQ664_000497"
     CDS             13268..14848
                     /gene="asp1"
                     /locus_tag="VQ664_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp1"
                     /protein_id="HET2788722.1"
                     /translation="MYYFIPAWYGSERTWHADITPWYFSHFRLEFDDTFHQIRLFQEQ
                     DIDSRLLVLAYQPHLRYFLYRHGVLETDTYSVFDVMQDFHNLHTQVLSIRDIEWDDDC
                     EFIYSPFTIIVQKNGKKFAKVEHGVEGFISDIQYFEPNGQIHMHHIMDDRGFISSIIF
                     FEDGQAAYQEYLNPKGVWQFRERLKEGGQVEVNPILGYRFKMLTYQNMGDLVAEFFEN
                     YLQTYVKDQDIFMLPSHSHHDQLVLDRLPSTNPKLLSLFIGRNPQDTFRDLDVTFEKS
                     DLILVDREDSLRLLQELYPERMHQCYHLSSFDTRLRLGRSQTKKESIIYFQLDFEQGI
                     DNQALLQVLSFVAENKDTEVIFGAFAASQEQMNEVEGIVESFIQENIQSENLGKAIDY
                     GDAENPLEENQHQDLRLQFVNLNDELDLIKTLEFVRLIVDLNRHPHLYTQIAGISAGI
                     PQINLVETVYVEHLKNGYLLTDVTEFSKAAHYYTDRLKEWNESLIYSIDKIKEHTGQQ
                     FLGKLEKWIEEVKNVKGT"
     gene            14832..16367
                     /gene="asp2"
                     /locus_tag="VQ664_000498"
     CDS             14832..16367
                     /gene="asp2"
                     /locus_tag="VQ664_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp2"
                     /protein_id="HET2788723.1"
                     /translation="MSKELNILQIGLANWENHYDIPENMSWYYFYPNSSKTLREIIEK
                     EDINRFHAVLIEDGQYSRDLFSYVKYFEPYTLFYNQNLQINDREVVDFLKKRCAQAID
                     FLSPQQLINDLSKSLFGGGYGDKLFPPTIQVNPNFTGAISYQGLDYVSLEGEFGQDFA
                     QLAYWAYNIMVQKTLPIELWLEYEKEGNCDFRLVIRKMWSGSVDDFFEEVIVSEKDLE
                     QALFMDSRDGDYFLSISVEARGRGTIKLGNLHQRWSRKQFGKFVLGGNILHDSKRDEI
                     NYFFHPGDFKPPLTVYFAGYRPAEGFEGYFMMKTLGCPFILFSDPRLEGGAFYLGTDE
                     LEGKVKDTITHYLDYLGFDHKDLILSGLSMGTFPALYYGASFEPHAIIVGKPLANLGT
                     IASRGRLDAPGVSNLAFDCLIHHTGGTSSQDMTELDQRFWKIFKQANFSKTTFGLSYM
                     KDEEMDPQAYEQLVSYLCNTGAKILSKGTAGRHNDDTDTNISWFLHFYRMVLETGFGR
                     EKR"
     gene            16364..16804
                     /gene="asp3"
                     /locus_tag="VQ664_000499"
     CDS             16364..16804
                     /gene="asp3"
                     /locus_tag="VQ664_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp3"
                     /protein_id="HET2788724.1"
                     /translation="MIITQRQSIYWGEVGGTYMYGTTVSYYLDKSVRLYNPLLPSGEI
                     LKTWFSSVNYQAARTQPQLPLLKRKQEYQLSLVFDCQPENGVYTKITFFDRYGDILEK
                     KVEKAKDFIFTYPEDSYTYQVSLLSAGFESLTFYHFSIKEIRSV"
     gene            16797..19169
                     /gene="secA2"
                     /locus_tag="VQ664_000500"
     CDS             16797..19169
                     /gene="secA2"
                     /locus_tag="VQ664_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system translocase SecA2"
                     /protein_id="HET2788725.1"
                     /translation="MFRRLGQDFQLRKVKKILKQINALKGKMSSLSDQELVAKTVEFR
                     QRLSEGESLDDILVEAFAVVREADKRILGMFPYDVQVMGAIVMHYGNVAEMNTGEGKT
                     LTATMPVYLNAFSGEGVMVVTPNEYLSKRDAEEMGQVYRFLGLTIGVPFTEDPKKEMK
                     AEEKKLIYASDIIYTTNSSLGFDYLNDNLASNEEGKFLRPFNYVIIDEIDDILLDSAQ
                     TPLIIAGSPRVQSNYYAIIDTLVTTLVEGEDYIFKEEKEEVWLTTKGAKSAENFLGID
                     NLYKEEHASFARHLVYAIRAHKLFTKDKDYIIRGNEMVLVDKGTGRLMEMTKLQGGLH
                     QAIEAKEHVKLSPETRAMASITYQSLFKMFNKISGMTGTGKVAEKEFIETYNMSVVRI
                     PTNRPRQRIDYPDNLYITLPEKVYASLEYIKQYHAKGNPLLVFVGSVEMSQLYSSLLF
                     REGIAHNVLNANNAAREAQIISESGQMGAVTVATSMAGRGTDIKLGKGVAELGGLIVI
                     GTERMESQRIDLQIRGRSGRQGDPGMSKFFVSLEDDVIKKFGPSWVHKKYKDYQVQDM
                     TQPEVLKGRKYRKLVEKAQHASDSAGRSARRQTLEYAESMNIQRDIVYKERNRLIDGS
                     RDLEDVVVDIIERYTEEVAADHYASRELLFHFIVTNISFHVKEVPDYIDVTDKTAVRS
                     FMKQVIDKELSEKKELLNQHDLYEQFLRLSLLKAIDDNWVEQVDYLQQLSMAIGGQSA
                     SQKNPIVEYYQEAYAGFEAMKEQIRADMVRNLLMGLVEVTPKGEIVTHFP"
     gene            19181..20692
                     /gene="gtfA"
                     /locus_tag="VQ664_000501"
     CDS             19181..20692
                     /gene="gtfA"
                     /locus_tag="VQ664_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system glycosyltransferase GtfA"
                     /protein_id="HET2788726.1"
                     /translation="MTIYNINLGIGWASSGVEYAQAYRAGVFRKLNLSSKFIFTDMIL
                     ADNIQHLTANIGFDDNQVIWLYNHFTDIKIAPTSVTVDDVLAYFGGEESHREKNGKVL
                     RVFFFDQDKFVTCYLVDENKDLVQHAEYVFKGNLIRKDYFSYTRYCSEYFAPKDNVAV
                     LYQRTFYNEDGTPVYDILMNQGKEEVYHFKDKIFYGKQAFVRAFMKSLNLNKSDLVIL
                     DRETGIGQVVFEEAQTAHLAVVVHAEHYSENATNEDYILWNNYYDYQFTNADKVDFFI
                     VSTDRQNEVLQEQFAKYTQHQPKIVTIPVGSIDSLTDSSQGRKPFSLITASRLAKEKH
                     IDWLVKAVIEAHKELPELTFDIYGSGGEDSLLREIIANHQAEDYIQLKGHAELSQIYS
                     QYEVYLTASTSEGFGLTLMEAIGSGLPLIGFDVPYGNQTFIEDGQNGYLIPSSSDHVE
                     DQIKQAYAAKICQLYQENRLEAMRAYSYQIAEGFLTKEILEKWKKTVEEVLHD"
     gene            20685..22022
                     /gene="gtfB"
                     /locus_tag="VQ664_000502"
     CDS             20685..22022
                     /gene="gtfB"
                     /locus_tag="VQ664_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system glycosylation chaperone
                     GtfB"
                     /protein_id="HET2788727.1"
                     /translation="MIELYDSYSQESRDLHESLVATGLSQLGVVIDADGFLPDGLLSP
                     FTYYLGYEDGKPLYFNQVPVSDFWEILGDNQSACIEDVTQERAVIHYVDGMQARLVKQ
                     VDWKDLEGRVRQVDHYNRFGACFAKTTYSADSEPIMTVYQDVNGQQVLLENHVTGDIL
                     LTLPGQSMRYFANKVEFITFFLQDLEIDTSQLIFNTLATPFLVSFHHPDKSGSDVLVW
                     QEPLYDAIPGNMQLILESDNVRTKKIIIPNKATYERALELTDEKYHDQFVHLGYHYQF
                     KRDNFLRRDALILTNSDQIEQVEAIVEALPDVTFRIAAVTEMSSKLLDMLRYPNVVLY
                     QNASPQKIQELYQLSDIYLDINHSNELLQAVRQAFEHNLLILGFNQTVHNRLYIAPEH
                     LFESSEVAALVETIKLALSDVDQMRQALGKQGQHANYVDLVRYQEIMQTVLGG"
     gene            22024..22203
                     /gene="asp4"
                     /locus_tag="VQ664_000503"
     CDS             22024..22203
                     /gene="asp4"
                     /locus_tag="VQ664_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory secretory system protein Asp4"
                     /protein_id="HET2788728.1"
                     /translation="MSEEDLFYKDVEGRMEELKQKPIKKEKETRGEKISKTFSLLLGL
                     MILIGLLFTLLGILR"
     gene            22208..22432
                     /locus_tag="VQ664_000504"
     CDS             22208..22432
                     /locus_tag="VQ664_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory secretory protein Asp5"
                     /protein_id="HET2788729.1"
                     /translation="MIEMLIVLAIILSLALIVLVTIQPRQNQLFSMDATSNIGKPSYW
                     QSNTLVKVLTLLVSLALFVLLLTFMVITYK"
     gene            22487..22567
                     /locus_tag="VQ664_000505"
                     /pseudo
     CDS             22487..22567
                     /locus_tag="VQ664_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(22803..23756)
                     /locus_tag="VQ664_000506"
     CDS             complement(22803..23756)
                     /locus_tag="VQ664_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HET2788730.1"
                     /translation="MSISQRTTKLILATCLACLFAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREEEIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYRQ"
     gene            complement(23824..25033)
                     /gene="sstT"
                     /locus_tag="VQ664_000507"
                     /pseudo
     CDS             complement(23824..25033)
                     /gene="sstT"
                     /locus_tag="VQ664_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            25172..25732
                     /locus_tag="VQ664_000508"
     CDS             25172..25732
                     /locus_tag="VQ664_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HET2788731.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQALHFVPNRNITVVSNFSRTD"
     gene            25789..26697
                     /locus_tag="VQ664_000509"
     CDS             25789..26697
                     /locus_tag="VQ664_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HET2788732.1"
                     /translation="MVLEKQLGHGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESGTVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLESHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFA
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDEPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            26649..27239
                     /locus_tag="VQ664_000510"
     CDS             26649..27239
                     /locus_tag="VQ664_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HET2788733.1"
                     /translation="MDCFILVTKENCEKKLRKGARMAIENYIPDFAVEAVYDLTVPSL
                     QAQGIKAVLVDLDNTLIAWNNPDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVE
                     KFGIDYVYWALKPFTFGIDRAMKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKP
                     LVQHDSIKTQINRTRERRVMRKITEKYGPITYKKGI"
     gene            27242..28348
                     /gene="yqeH"
                     /locus_tag="VQ664_000511"
     CDS             27242..28348
                     /gene="yqeH"
                     /locus_tag="VQ664_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HET2788734.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSDALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAHEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKLEGASAFYDKHLGTLLTPPNSKEKEDFPRLVQHVFTIKDKTD
                     LVISGLGWIRVTGTAKVAVWAPEGVAVATRKAII"
     gene            28562..28873
                     /gene="yhbY"
                     /locus_tag="VQ664_000512"
     CDS             28562..28873
                     /gene="yhbY"
                     /locus_tag="VQ664_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HET2788735.1"
                     /translation="MSLASKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            28925..29554
                     /locus_tag="VQ664_000513"
     CDS             28925..29554
                     /locus_tag="VQ664_000513"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HET2788736.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEKNPDTDYYFIIGADMVDYLPKWYRIDELVDMVQFVGVQRPRYKV
                     GTSYPVIWVDVPLMDISSSMVRDFLAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            29554..30147
                     /gene="yqeK"
                     /locus_tag="VQ664_000514"
     CDS             29554..30147
                     /gene="yqeK"
                     /locus_tag="VQ664_000514"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HET2788737.1"
                     /translation="MSYQDYINCSREALLEKMAEFLPEKRLTHCLGVERAAMELAQRF
                     GVDVEKASLAGLLHDYAKKLSNQEFLALIDRYQLDPDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEVHTVGAGQMTDLDKVIYVADYIEHNRAFPGVDVAREIANLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKEN"
     gene            30148..30648
                     /locus_tag="VQ664_000515"
     CDS             30148..30648
                     /locus_tag="VQ664_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HET2788738.1"
                     /translation="MKTAFIIIDVQNILVETGFQTKSLLGKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEERFADVL
                     DYKHIF"
     gene            30661..31014
                     /gene="rsfS"
                     /locus_tag="VQ664_000516"
     CDS             30661..31014
                     /gene="rsfS"
                     /locus_tag="VQ664_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HET2788739.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHVEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            31334..32074
                     /locus_tag="VQ664_000517"
     CDS             31334..32074
                     /locus_tag="VQ664_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET2788740.1"
                     /translation="MATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKERKKLLELA
                     CGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGKYD
                     FVTCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQTDEVFPGYSYHENA
                     EDFAMLWDTYEDEVPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYDILLEQAG
                     FKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            32084..33181
                     /locus_tag="VQ664_000518"
     CDS             32084..33181
                     /locus_tag="VQ664_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HET2788741.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRAQMALENGADLVVELPFLVSVQAADFFGQGAVDILDRLGIDSLVFGTEEVLD
                     YQKIADLYTEKGAEMEKFVKNLPDSLSYPQKTQAMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHPIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQA
                     SKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVELVTTKRY
                     TKARVRRLLTYILVQARENVLPEAIHVLGFTEKVRQHLKSLKGQVNLVSRIGKEPWDA
                     MTQKADQIYQLGKPSIAEQNFGRVPIRIETN"
     gene            33419..33673
                     /locus_tag="VQ664_000519"
     CDS             33419..33673
                     /locus_tag="VQ664_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HET2788742.1"
                     /translation="MEAVLYSTFRNHLKDYMKKVNDEFEPLTVVNKNPDEDIVVLSKS
                     EWDSIQETLRIAQNKELSDKVLRGMAQVRAGSTQVHVIEE"
     gene            33677..33931
                     /locus_tag="VQ664_000520"
                     /pseudo
     CDS             33677..33931
                     /locus_tag="VQ664_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152757.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
     gene            34122..35735
                     /locus_tag="VQ664_000521"
     CDS             34122..35735
                     /locus_tag="VQ664_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HET2788743.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
     gene            35865..36491
                     /gene="gmk"
                     /locus_tag="VQ664_000522"
     CDS             35865..36491
                     /gene="gmk"
                     /locus_tag="VQ664_000522"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HET2788744.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            36516..36830
                     /locus_tag="VQ664_000523"
     CDS             36516..36830
                     /locus_tag="VQ664_000523"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HET2788745.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            36896..39292
                     /locus_tag="VQ664_000524"
     CDS             36896..39292
                     /locus_tag="VQ664_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HET2788746.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLKSQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKAMLPGFLNSSYDKILYPLEGLSQEERVRLFGSEDSLAFSSLDLAKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGTVTIVQKEVQRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEAAYK
                     QDSNPRYHAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSRSIRYYGTGTQKAYDEL
                     AELFPQARILRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNSQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            39305..40240
                     /locus_tag="VQ664_000525"
     CDS             39305..40240
                     /locus_tag="VQ664_000525"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HET2788747.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEELMKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGTLFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEGQGNPGEILSIGKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            40233..41546
                     /gene="rsmB"
                     /locus_tag="VQ664_000526"
     CDS             40233..41546
                     /gene="rsmB"
                     /locus_tag="VQ664_000526"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HET2788748.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLSAADKG
                     LVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNAVLRRILREGWPDIASIKRKNKRDSIAYSLPVWLVAKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANNSLLATTGLVKEQGHFAG
                     HNLFADGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVEDRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            41561..42301
                     /locus_tag="VQ664_000527"
     CDS             41561..42301
                     /locus_tag="VQ664_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HET2788749.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVFMNEEDAE"
     gene            42298..44277
                     /gene="pknB"
                     /locus_tag="VQ664_000528"
     CDS             42298..44277
                     /gene="pknB"
                     /locus_tag="VQ664_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HET2788750.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSVE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            44392..45150
                     /locus_tag="VQ664_000529"
     CDS             44392..45150
                     /locus_tag="VQ664_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HET2788751.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAQPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            45152..45601
                     /locus_tag="VQ664_000530"
     CDS             45152..45601
                     /locus_tag="VQ664_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HET2788752.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            45663..45892
                     /locus_tag="VQ664_000531"
                     /pseudo
     CDS             45663..45892
                     /locus_tag="VQ664_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
BASE COUNT        13981 a         8236 c        10309 g        13366 t
ORIGIN      
        1 agcacctcag cgtctgaatc ggcatcaacg agcgcctcag cttcagcaag taccagtgcg
       61 tcagcctcag cgtcaaccag tgcgtcagct tccgcatcaa cgagtgcgtc tgaatcggca
      121 tcaacctcag caagtacaag tgcatcggct tcagcaagca ccagtgcttc ggcttcagca
      181 agcacgtcag catcaacaag cacaagtaca tcggcaagca cgtcagcatc gacaagtgca
      241 agcacatcgg cgtcaacaag tgcaagtacg tcagcatctg aatcggcctc aaccagtgcg
      301 tcgacttcag caagtacaag cgcctcagcc tcagcaagta tctcagcgtc tgaatcggca
      361 tcaaccagcg cctcagcctc agcatcaaca agtgcatcag cttcagcaag cacctcagcg
      421 tctgaatcgg catcaacgag tgcctcagct tcagcaagca ccagtacctc agcttctgaa
      481 tcggcctcaa ccagtgcctc agcttcagcg tcaaccagtg cctcagcttc tgcatcaacc
      541 agcgcctcgg cctcagcaag cacctcagca tctgaatccg catcaacgag tacctcagct
      601 tctgaatcgg cctcaacaag tgcctcggcc tcagcaagca caagcgcctc agcttcagca
      661 agtaccagtg cgtcagcttc cgcatcaacg agtgcttcgg cttcagcctc aacgagtgcc
      721 tcagcttcag cgtcaaccag tgcttcagcc tcagcatcaa cgagtgcttc ggcttcagca
      781 agtaccagtg cttcggcctc agcatcgaca agtgcctcag cttcagcaag tactagcgcc
      841 tcagcctcag catcaaccag tgcctcggct tcagcaagta ctagcgcctc agcttcagcg
      901 tcaaccagtg cctcagcatc agcaagcacc tcagcgtctg aatcggcatc aaccagtgcg
      961 tctgagtcag catcaacgag tgcgtcagcc tcagcaagta catcagtttc aaattcagca
     1021 aaccattcga actcacaagt tggaaatgct tctggatcga caggtaaatc ccaaaaagaa
     1081 ttgcctaata caggtactga gtcgtcaatt ggatctgtgt tacttggagt tctagcagct
     1141 gttacaggta ttggattggt tgcgaaacgc cgtaaacgtg atgaagaaga gtaagacaac
     1201 ctgtaaagtt aggctaaact aactcgcgca cataaatcaa ggagaaaatt gctagtggat
     1261 gataaaatta cggtcattgt accagtatac aatgtagaaa actatctgag gaaatgtcta
     1321 gatagtatta tttctcaaac atataaaaat attgagattg ttgtcgttaa tgatggttct
     1381 acggatgctt caggtgaaat ttgtaaagaa ttttcagaaa tggatcaccg aattctctat
     1441 atagaacaag aaaatgctgg tatttctgcc gcacgaaaca ccggtctgaa taatatgtcc
     1501 ggaaattatg tgacctttgt ggattcagat gattggattg agttagatta tgtagaaacc
     1561 ctatataaaa aaataacaga atatcaagct gatattgcag ttgggaatta ctattctttc
     1621 aacgaaagtg aaggaatgtt ctactttcat atatcaggag actcctatta tgataaggta
     1681 tatgacaatg tttccatctt tgagaacttg ttatgaaact caagaaatga agagttttgc
     1741 tttgatatct gcttgtggta aactctataa ggcaagattg tttgagcagt tgcgctttga
     1801 catgggtaaa ttaggagaag atggttacct caatcaaaag gtatatttat tatcggaaaa
     1861 ggtaatttat ttaaataaag gtctttatgc ttatcggatt agaaaaggta gtctatcaag
     1921 agtttggaca gaaaagtgga tgcacgcctt agttgatgct atgtctgaac gtattacgct
     1981 actagctaat atgggatatc ctctagagaa acacttggca gtttatcgtc agatgttgga
     2041 agtcagtctc gccaacggtc aagctagtgg tttatctgac acagcaatat ataaagagtt
     2101 tgaaatgaaa aaaagacttt taaatcagtt aacggtacaa gaatcaagtg aaaagaaagc
     2161 cattgtccta gcagcaaact atggctatgt agaccaagtt ttaacgacaa tcaagtctat
     2221 ttgttatcat aatcgttcga ttcgttttta tctgattcat agcgattttc caaatgaatg
     2281 gattaagcaa ttaaataagc gcttagagaa gtttgactca gaaattatta attgtcgggt
     2341 aacttctgag caaatttcat gttataaaac ggatattagt tacacagttt ttttacgcta
     2401 tttcatagct gatttcgtgc aagaagataa ggccctctac ttggactgtg atttacttgt
     2461 aacgaaaaat cttgatgatt tgtttgctac agacttacaa gattatcctt tggctgctgt
     2521 tagagatttt gggggcagag cttattttgg tcaagaaatc tttaatgccg gtgttctctt
     2581 ggtaaacaat gctttttgga aaaaagagaa tatgacccaa aaattaattg atgtaaccaa
     2641 tgaatggcat gataaggtgg atcaggcaga tcagagcatc ttgaatatgc tttttgaaca
     2701 taaatggttg gaattggact ttgattataa tcatattgtc attcataaac agtttgctga
     2761 ttatcaattg cctgagggtc aggattatcc tgctattatt cactatcttt ctcatcggaa
     2821 accgtggaaa gatttggcgg cccaaaccta tcgtgaagtt tggtggtact atcatgggct
     2881 tgaatggaca gaattgggac aaaaccatca tttacatcca ttacaaagat ctcacatcta
     2941 tccaataaag gaacctttca cttgtctaat ctatactgcc tcagaccata ttgaacaaat
     3001 tgagacattg gttcaatcct tgcctgatat tcagtttaag atagcagcta gagtaatagt
     3061 tagtgatcga ttggctcaga tgacaattta tccaaacgtg actatattta acggaattca
     3121 ctatttggta gatgtcgata atgaattggt agaaaccagt caagtacttt tagatattaa
     3181 tcatggtgaa aaaacagagg aaattatcaa tcaatttgca agacttggaa aaactatttt
     3241 gtcctttgaa aataccaaaa cctatgaagc aggtcaggag gtatatgctg ttgaccaagt
     3301 tcaagcaatg attgagaaat tgagagaaat aagcaaatga agaaaaatca tttagtagga
     3361 gatgctctga ttttgactgt tagtgatcag attgaagagt tggattatct ccttgaatcc
     3421 ttgccaaata tctgttttta tattgcagca cctgttcaat tttccgagaa aatccgtagc
     3481 ttagaaacga actataatgt ccgtctccga acgattacaa atgaagaaca gctaaacttt
     3541 ctagtcgata cctgtgactt tttactagat atcaatcact ttcaagaagt agatgctatt
     3601 gtctccaagt ttgtacaggc tggaaaatct gtctttgctt ttgacaatac agtccatgga
     3661 aatcaggggc aggaagtttt tctatcaagt acaccagaca aattggtttc tagagtgaga
     3721 gactatctga atgaagtcag agtaggcacc aatcatcaag aaaaaatcat ccaagatggg
     3781 acttggaatg tctttaaaat cgatgataag gctcacttca ttgtaggagc aaatgtcatc
     3841 tgcagaaatt ttgaaaattt tcatgtctct tctggtaagt taatactgca tgatggtgtt
     3901 tttatcaaca actcttgtag ttttaactgt atggaaagaa ttgaaatcgg agctggtacc
     3961 atgatgggag agggtgttcg tttttatgat cacgaccata tttatactgc tgaaaagatt
     4021 gaaaagtggc agtggactac agcgccgatt agagttggca gagactgctg gataggaagt
     4081 aatgtcacga ttttaaaagg agtgacgatt ggggataata ccattattgg agcaggttgt
     4141 ctcatacgca atgatattcc atcaaacagt gtagtttata ataatggaaa tcttgttgta
     4201 aagagaagag attaagaggg aaatagaata aatcaagtct aggaaagtta gtatatggaa
     4261 aatgaactaa ttagtattgt agtcccaatc tacaacgttg agaattattt gcgacagtgt
     4321 ttggatagta ttcaaaaaca aacttatccg aattttgaat gtatcatggt taatgatggc
     4381 tctccagatc attcatccaa aatatgtgaa gaatttgtag agaaagattc tcgtttcaaa
     4441 tattttgaga aagcaaacgg cggtctttca tcagctcgta acctaggtat tgaatgttcg
     4501 ggggggggcg tacattactt ttgtagactc tgatgattgg ttggaacatg atgctttaga
     4561 ccgattatat ggtgctttga aaaaggaaaa cgcagatatt agtatcgggc gttataattc
     4621 ttatgatgaa acacgctatg tgtatatgac ttatgttacg gatccagatg attctctgga
     4681 agtgatagaa ggtaaagcaa tcatggatag ggaaggtgtc gaagaagtca gaaatgggaa
     4741 ctggactgta gctgtcttga agttattcaa gagagagtta ctacaagatt taccatttcc
     4801 tataggaaaa attgcagagg atacttactg gacatggaag gtacttctaa gagcttcgag
     4861 gatagtctat ttgaatcgtt gtgtttactg gtaccgtgtt ggtttatctg atactttatc
     4921 gaatacatgg agtgaaaagc gtatgtatga tgaaatcggg gctagggaag aaaagatagc
     4981 tattttagca agttcagact atgacttgac caatcatatt ttgatttata aaaatagatt
     5041 acaaagagtg atagcaaaat tagaagaaca aaatatgcag ttcacagaga tttatagaag
     5101 aatgatggaa aaattgtctt tacttccgta gatagtaata aaaaatgaga tagcgtaata
     5161 tgaaactaca tttaacaaat ttatacggca tggctggtga tagtacggtt atcttagctc
     5221 aaaatgctgt tcaaaagata gctagtcaac tgggatttag agaggttggt atttattttt
     5281 acaacattgc ttcagatagt ccttctgaaa tgaataagcg tctggatggt attatggcca
     5341 gtatttctat tggggatatt ttagtctttc agtctccaac ctggaatggc tttgaatttg
     5401 atcgtctctt gtttgataag ttgaaggata tgcaggtgaa aattatttgc tttatccatg
     5461 atgttgttcc cctcatgttt gatagtaact attatctcat gaaagactat atgtacatgt
     5521 ataatctatc agatgttttg atagtgccgt cagagagaat gaaaacacgc ctgatggaag
     5581 aaggattgac gactaagaag attcttgttc aagggatgtg ggatcatcct catgatttat
     5641 ccttatacac ccctgctttt aaaaaagaac ttttttttgc tggaagttta gagcgttttc
     5701 cagacttaca aaattggtct caagatacgc ctttgagagt attttcaaat aaaggggaag
     5761 ctagttctag tgctagaaat ctcagcatcg aaggatggaa aaaagatgag gaattgttgc
     5821 tagaattatc aaagggtgga tttggccttg tctggggaac ttatcaaaac gatggagaaa
     5881 gcaaccaata ttatacctta aatatatctc ataaggtgag tacctatctg acagcgggca
     5941 tcccagtcat tgtaccaagt agcttgtcaa ctgctaaatt tatagtagat caaggcttag
     6001 gctttgtggc gaatagtcta gaagaagttc atgcgatagt tgataaaatg aatctacaag
     6061 aatatcaaga aatgacgaat cggataaaaa cctttagtta tttgctaaaa gaaggttatt
     6121 ttactaaaaa attattggta gatgcaattt accatttggg agttgaataa gagaacaaga
     6181 tgattaaaac aattgtatta gctggtgatc gtaattacat caggcagtta gaaacaacca
     6241 taaaatctat tttataccac aatcgagatg ttaagattta tattttaaat caagatatta
     6301 tgccagattg gtttcgcaaa ccacgaaaaa tagctcgcat gttaggtagt gagattatcg
     6361 atgtgaagct acctgaacaa actgtgtttc aagattggga aaagcaagat cacattagta
     6421 gcattaccta tactagatat tttattgcag attatatcca agaagataag gttttatatt
     6481 tagacagtga tttgattgta aatacttctt tagagaaatt atttagtatt tgtttagaag
     6541 aaaaatcact cgcagcagtt aaagatacag atggaattac atttaatgca ggtgttttat
     6601 taatcaacaa taaaaaatgg cgtcaagaga aattaaaaga acgactaatt gaacagagca
     6661 ttgttacaat gaaggaagtt gaagaaggcc gtttcgagca ttttaatggt gatcaaacga
     6721 tttttaatca ggtcttacaa gatgattggt tagagctgga taaagaattt aaccttcaag
     6781 tgggtcatga tgtaactgct ttttataata aatgggaaaa ttattttaat gagttagtac
     6841 ctcctagtat tattcatttt gtgtcttaca gaaaaccctg gaccaccttg atagccaatc
     6901 gttatcgtga tttatggtgg gaatttcatg atttggaatg gactaaaatt ttacaacatc
     6961 atatagggga gtttgaactg acatcgtctt tagataagga attttcttgt ttaactttga
     7021 caaattccca agatttagaa ggaatagaag agttagtcac agctttacca gatgtggtat
     7081 ttcatattgc tgcttggacg gatatgggtg ataagctgat aaaattagct gtgtatgata
     7141 atgtgagatt gcatccacaa attgttcctc ctgtattaga taagctgaaa aagtcaacaa
     7201 atctatattt ggatatcaat catggtagtg cagatgagaa ctttttaaaa tctttgcaag
     7261 aacaagaaaa aacgctacta gcttttcaat cgactcagca cggagagtta ggacaaatcg
     7321 ttttcgaaaa tgggaaagtt tcctttatga ttgatacgat taaagatttt aagaaaaacg
     7381 gacatcttac ctgttttcga caacttccaa gtttaacttg tttaacgttt acggcttctc
     7441 aggatatcga acaattggat tacttggctg gacagttgcc aaatgttgtt tttcaagttg
     7501 ctgcttggac agctatgggg ccaaaattat atgatttgtc taatcgttat cctaatattc
     7561 agctctatcc ggcaatttct agagataagc tagacgagtt gaaggagaag atggatgctt
     7621 atttagatat caacctactg acttcaacat ccgatatcgt tgcagaaatg gctcatctat
     7681 ctaaacctat actagccttt tataaatctc aaaatgggaa taatggccaa aggttgtatt
     7741 caagtgaaca tcctgaacga atgttggctg atttgcaaaa attgataact aaggatatgc
     7801 tagaaaaacc gcttgatata atccaggtga aagggataga tgaaaccttg gattatatta
     7861 ttgaacacaa ctcttcttta gttcgttttg gagatgggga aatcaatatg cttgcagggc
     7921 attcaattcc ctaccaggat tatgatgaag agttggtttc aatcatgagg gacattatcg
     7981 gccaagaaag tcgagaagat ttagtagtgt gccttcctga tgcttttaca gatcgtttta
     8041 ggtttacatc gtgggcgatt ccattttgga aagatcacat ggatcattat atggattttt
     8101 acagagagtt atgcagtgat tcatggtatg gctcaacctt tgtatctcgc ccttatatcg
     8161 attttgaaga caagagtcaa gctaaagctc aatttgaaaa attgaaaagc atttgggaaa
     8221 accgtgactt actgatagtc gaaggtgcga cttctcgttc aggtgtcgga aatgatttat
     8281 tcgatgaggc aaattctatt aagcgaatta tctgtccttc tcatagtgcc ttttctagag
     8341 ttcatgaaat tgaacaagaa attgaaaagt atgctggtgg tcgcttgatt ttatgtatgc
     8401 tgggtcctac agcaaaagtt ctgagttata atctatgcca gatgggctat caagttttgg
     8461 atgtaggcca tattgactca gagtatgaat ggatgaaaat gggagctaaa actaaggtta
     8521 aattttctca taaacatact gcagagtata attttgatca agatattgaa tttattgatg
     8581 atgaaaccta taacagtcag attgttgcac gaatattaaa ctagactatt taaaataaat
     8641 gataaggatt taaaatgaga aataccaaac gcgctgtagc atttgcaggt gattacgctt
     8701 atattcgaca aatcgaaacg gcgatgaagt cactctgtag acacaatagt catttgaaaa
     8761 tttatctgct aaatcaggac attcctcagg aatggtttag tcaaataaga atatatttac
     8821 aagagatggg gggcgacttg attgactgca agttaattgg ctcacagttt caaatgaatt
     8881 ggtctaataa attacctcat atcaatcata tgacatttgc acgctatttt attccagatt
     8941 ttgtaacaga agataaagtt ctctatctag atagtgattt gattgtgact ggtgatttga
     9001 ccgatttgtt tgaattagac ttaggtgaaa attatttggc agcagctcgt tcttgctttg
     9061 gagcaggagt cggcttcaat gctggtgttc tcttgattaa caacaaaaaa tggggatctg
     9121 aaactattcg acaaaaattg attgacttaa cagaaaaaga acatgagaat gtggaagaag
     9181 gagaccagtc aattttgaat atgttgttta aagatcaata tagttccctt gaagatcaat
     9241 ataattttca aataggatat gattatgggg cggcagcctt taaacatcaa ttcatttttg
     9301 atattccgct cgaaccactg ccactaattt tacactatat ttctcaggat aagccttgga
     9361 atcaattttc tgttggacgt ctaagagaag tttggtggga atactctttg atggattggt
     9421 ctgttatttt aaatgaatgg ttttcaaaga gtgtgaagta tcctagtaaa tcacaaatat
     9481 ttaagttaca atgtgttaat ttaacgaatt cttggtgtgt cgagaaaatc gattatttgg
     9541 cggagcaatt gccagaagtt cattttcata ttgttgctta tacaaatatg gcaaatgaac
     9601 tactagcttt aacgcgtttt cctaatgtta ccgtatatcc aaattcctta ccaatgttat
     9661 tggaacaaat agtaatagct tcagatttgt atttggattt gaatcatgat cgaaaattag
     9721 aagatgcata tgagtttgtg cttaagtaca aaaaaccaat gatagctttc gacaatactt
     9781 gctctgaaaa tctttctgag atttcatatg aaggtatcta tccaagctcc attccgaaaa
     9841 aaatggttgc agcaatcaga tcttacatga ggtagagaac agtatgagaa aatcaatagt
     9901 attagcggca gataatgcct atcttattcc tttagagacg actataaagt ctgtattgta
     9961 tcacaataga gatgttgatt tttatattct caacagtgat atagctcctg aatggtttaa
    10021 attattgggg agaaaaatgg aagttgtgaa ttctacaatt cgcagtgtac acattgataa
    10081 agaacttttt gaaagctata aaacaggacc tcatataaat tatgcttctt actttagatt
    10141 ttttgcgaca gaagtggttg aatctgatag ggtattgtat ctggattccg atatcattgt
    10201 aactggggaa ctagctactt tgtttgagat agatctcaaa ggatattcaa ttggtgctgt
    10261 tgatgatgtc tatgcctatg aaggacgaaa atctggattt aatgctggta tgttactaat
    10321 ggatgttgca aaatggaaag aacactctat tgtcaatagt ttattggaat tagcggccga
    10381 gcaaaatcaa gttgttcatc ttggggatca gagtatttta aatatttatt ttgaggataa
    10441 ttggctagcc ttagataaaa catataatta tatggtgggt gttgatattt atcaccttgc
    10501 tcaagaatgt gaacgtctag atgacaatcc acctacaatt gttcactatg ctagtcatga
    10561 taaaccttgg aatacatata gtatatctag actacgtgaa ttatggtggg tttatagaga
    10621 tttggattgg tcagagattg cttttcaacg ttccgattta aattattttg aaagaagcaa
    10681 tcagtctaaa aaacaagtga tgcttgtgac atggagtgca gatataaaac atttagagta
    10741 tttagtacaa cggttacctg attggcattt tcatttggct gcaccgtgtg attgttctga
    10801 ggagctgacc tctctatcac agtatacgaa tgtaacagta tatcaaaatg tattacatag
    10861 tagaattgat tggctattgg acgattctat agtttattta gatattaata caggtggaga
    10921 ggtttttaat gtagttacaa gggcacaaga aagtggcaag aaaatcttcg cttttgatat
    10981 cacacgtaaa agtatggatg atggactcta tgacggtatt ttttctgtgg agagaccaga
    11041 tgatttagtg gatagaatga agaatataga gatagagtaa tgagtgaatt aattagtgtt
    11101 gtggtaccga tatacaatac gggaaaatat ttagtggagt gtgtcgagca tattctgaag
    11161 caaacctatc aaaatataga aattatttta gttgatgacg gttctacgga taattctggg
    11221 gaaatttgtg atgcttttat gatgcaagat aatcgtgtgc gagtattgca tcaagaaaat
    11281 aagggggggc agcacaagct aaaaatatgg ggattagtgt agctaaggga gagtacatca
    11341 cgattgttga ttcagatgat atcgtaaaag aaaatatgat tgaaactctt tatcagcaag
    11401 tccaagaaaa ggatgcagat gttgttatag ggaattacta taattatgac gaaagtgacg
    11461 ggaattttta tttttatgta acagggcaag atttttgcgt cgaagaatta gctatacaag
    11521 aaattatgaa ccgtcaagca ggagattgga aattcaatag ctcggccttt atattgccga
    11581 catttaagtt gattaaaaaa gaattattca atgaagttca cttttcaaat ggtcgccgct
    11641 ttgatgatga agcaactatg catcgctttt atcttttagc ctctaaaatc gtctttataa
    11701 acgataatct ctatctgtat agaagacgtt caggaagcat catgagaacg gaatttgatc
    11761 tttcctgggc aagagatatt gttgaagtgt tttctaagaa aatatcggat tgtgtcttgg
    11821 ctggtttgga tgtctccgtt ctgcgtattc gatttgtcaa tcttttaaaa gattataagc
    11881 aaactttaga ataccatcaa ttaacagata ctgaggaata taaagatatt tgtttcagat
    11941 taaagttgtt ttttgatgca gaacaaagaa atggtaaaag ttgaaataaa agaattgtta
    12001 tttaccatat cacaaacaat gaaggtgagg ggagtgtttt atgactaaga tttattcgtc
    12061 aatagcagta aaaaaaggac tatttacctt atttctactg tttatctatg tattgggaag
    12121 tcgtattact ctcccttttg ttgacctaaa tactaaagat tttttaggag gttcaacagc
    12181 ctatctagcc ttctcagccg ccctaacagg tggaaatcta agaagtttgt caattttttc
    12241 tgttggattg tccccttgga tgtcagctat gattttatgg cagatgtttt ctttttctaa
    12301 acggttgggt ttaacatcta cgtctataga aatacaagat cgccgtaaaa tgtacctgac
    12361 cttgatgata gctgtcattc aatcattggc agttagcttg agactgccag tacaatcctc
    12421 ctattctgca atattggttg ttctaatgaa tacaatattg ctgatagcag gaacattttt
    12481 tcttgtttgg ttgtcagatt taaatgcgag tatggggatt ggaggttcta tagtcattct
    12541 cctatccagt atggttttaa atattcctca ggatgttttg gaaacatttc agacagtaca
    12601 cattccaaca gggattattg tgttacttgc tttattaacc cttgtctttt cttatttact
    12661 tgcccttatg tatcgagctc gctatttggt tcctgttaat aaaattggct tacacaatcg
    12721 atttaaacgc tatttttatc tcgaaatcat gttgaatcct gcaggtggga tgccttatat
    12781 gtatgtgatg agttttctta gtgtaccagc ttatttgttc atcttgttgg gatttatttt
    12841 ccctaatcat tcagggttag cggctttatc aaaggaattt atgattggaa agcctttgtg
    12901 ggtctatgtt tatatttcgg tcttattttt atttagtatc atttttgctt ttgttacgat
    12961 gaatggagaa gagattgcag accgtatgaa aaaatctgga gaatacattt atggtattta
    13021 tccaggtgcg gatactagtc gatttattaa tcgattggtc cttcgtttct cagtcatagg
    13081 tggtctcttt aatgtggtta tggcaggtgg tcccatgctt tttgttttgt ttgatgaaaa
    13141 gttattacga ttggcaatga ttccaggttt gtttatgatg tttggaggca tgatttttac
    13201 gattagagac gaggtcaagg ctttaaggct aaatgagacc tataaacctt tgatttagga
    13261 gacttttatg tattatttta ttccagcttg gtatgggtca gaaagaacat ggcatgcaga
    13321 tatcactcca tggtattttt ctcattttcg tctagagttt gatgatacct ttcaccagat
    13381 ccggctcttt caagagcaag atatagattc tcgtctatta gtattagctt accagcctca
    13441 tctacgttat tttttatata gacatggtgt gttagaaacg gatacttatt ccgtttttga
    13501 tgttatgcaa gattttcata atctccatac ccaagtttta agcattagag atattgagtg
    13561 ggatgatgac tgtgaattta tttatagtcc ctttacgatt atcgttcaaa aaaatgggaa
    13621 gaaatttgct aaggttgaac atggagttga aggcttcatc agtgatatac agtattttga
    13681 accaaatggt caaatacata tgcaccatat catggatgat cgagggttta tatcgagtat
    13741 tatttttttt gaagatgggc aagcagccta tcaagaatat ttgaatccta agggagtttg
    13801 gcaatttaga gagcgtttaa aagaaggagg acaggtagaa gtcaatccaa ttttgggtta
    13861 tcgctttaaa atgcttacct atcaaaatat gggagatctg gtggcagaat tttttgagaa
    13921 ttatctgcaa acgtatgtga aggatcagga tatttttatg cttccttctc attctcatca
    13981 tgaccagttg gtactagatc gtttacctag tactaatcct aaactgttga gtctgttcat
    14041 tggacgtaat cctcaagata cctttaggga tttagatgta acttttgaaa aatcggattt
    14101 gattttggtg gatagagagg atagtttacg attgttgcag gagttgtatc ctgaacgaat
    14161 gcatcaatgt tatcatttat catcttttga cacccgatta cgattgggac gaagccaaac
    14221 taagaaagaa tccatcattt attttcaact ggattttgag caggggattg ataatcaagc
    14281 tctgcttcaa gtcttgtcct ttgtcgctga aaataaggat actgaggtga tttttggagc
    14341 ctttgctgct agtcaggagc aaatgaatga ggttgaaggg attgttgagt ctttcatcca
    14401 agaaaacatt caatccgaaa atctgggaaa ggcgattgat tatggtgatg cagaaaatcc
    14461 cctggaagaa aatcaacacc aggacttacg cttacagttt gttaacttga atgatgagtt
    14521 agatttgata aaaacactag aatttgtccg tttgattgtg gatttaaata gacatcctca
    14581 tctctacaca cagattgctg ggattagtgc aggaattcct caaatcaacc tagttgaaac
    14641 cgtctatgtg gaacatttaa aaaatggtta tttgctgaca gatgtgacag aattttctaa
    14701 ggctgcacat tattacacag ataggttgaa ggagtggaat gagtccttga tatattcaat
    14761 tgataagatt aaggagcaca caggacaaca atttcttgga aaattagaga aatggataga
    14821 ggaggttaaa aatgtcaaag gaacttaata ttttacagat aggacttgcc aattgggaaa
    14881 atcactatga catacctgaa aatatgagtt ggtattattt ttacccaaac tcatcaaaaa
    14941 cccttcgtga aataatcgaa aaagaggata ttaaccgttt tcatgcagtt ttaatagaag
    15001 atggtcagta ttccagagac ttattttcct atgtaaaata ttttgaacct tatactttgt
    15061 tctataacca gaatctacaa ataaatgata gagaggttgt ggattttcta aaaaaacgat
    15121 gtgcacaagc aattgatttt ttaagtcccc aacaactaat caatgattta agtaaatctc
    15181 tttttggcgg tgggtatggt gataaactct ttcctccgac gatacaagtc aatccaaatt
    15241 ttacaggagc tatttcttat caaggattgg attatgtcag tttggaaggt gagtttgggc
    15301 aagattttgc ccagcttgcc tattgggctt ataatattat ggtgcaaaaa acactcccta
    15361 ttgagttgtg gcttgaatat gagaaggaag gcaattgtga ctttcgttta gtaatccgta
    15421 aaatgtggag tgggtctgtt gatgatttct ttgaagaagt aatagtatct gaaaaagact
    15481 tggagcaagc actttttatg gatagtcgag acggagacta ctttctctcg atatctgttg
    15541 aagcaagagg tcgtggaact atcaaactag gtaatcttca ccaacgatgg agtcgaaaac
    15601 aatttggtaa gtttgtactt ggtggaaata tcctacatga ttccaagcgt gatgaaataa
    15661 actatttctt ccatccaggt gattttaaac cgcctttgac tgtctatttt gcaggttatc
    15721 gacctgcaga aggattcgag ggttacttta tgatgaaaac tcttggatgt cccttcattt
    15781 tattttctga tccacgttta gaggggggag ctttttatct cggaacggat gagctagagg
    15841 gaaaagtaaa ggatacgatc actcactatc ttgattattt aggctttgat cataaggatt
    15901 tgattttatc aggtctttct atgggaacgt ttccggctct ctattatggt gcttcttttg
    15961 aaccccatgc catcatagtt ggtaagccct tggctaattt aggaactata gctagtcgtg
    16021 gacgtttgga cgcaccgggt gtctctaact tagcttttga ttgtttaatt catcatacag
    16081 gtgggacaag ttctcaagat atgacggagt tggatcagcg tttttggaaa atttttaaac
    16141 aagcaaattt ttcaaagaca acctttggtt tatcctatat gaaagatgaa gaaatggatc
    16201 cacaagccta tgaacaatta gtgtcttatc tgtgtaatac aggtgcgaag attttatcta
    16261 aaggaactgc tggacgacac aatgatgata cagataccaa tatttcttgg tttttgcact
    16321 tttatagaat ggtcttagag actggttttg gaagggagaa aagatgatta ttacacagag
    16381 acagtctatt tattggggag aagttggtgg gacttatatg tatggaacaa ctgtatctta
    16441 ttaccttgac aaaagtgttc gtctgtataa tcctctattg ccatctggtg agattctaaa
    16501 gacttggttt tctagtgtca attaccaggc tgcacgaacc caacctcagc ttcccttatt
    16561 aaaaagaaag caggagtatc aactatcact ggtttttgat tgtcagcctg aaaatggagt
    16621 ttataccaag ataacttttt ttgaccgcta tggtgatatt ttagaaaaaa aggtagaaaa
    16681 agcgaaagat ttcatattta cttatccaga agatagttat acttatcaag tttctctttt
    16741 aagtgctgga tttgagtcct taacttttta tcatttttct atcaaggaga tcagaagtgt
    16801 ttagacgttt aggtcaagat ttccagctta ggaaagtgaa aaagatttta aagcagatta
    16861 atgccctgaa aggcaagatg tcctctcttt cggatcaaga attagtagct aaaacagtag
    16921 agtttcgtca gcgtctttcc gagggagaaa gtctagacga tattttggtt gaagcttttg
    16981 ctgtggtgcg tgaagcagat aagcggattt tagggatgtt cccctatgat gttcaagtca
    17041 tgggagctat tgtcatgcac tatggaaatg ttgctgagat gaatacgggg gaaggtaaga
    17101 ccttgacagc taccatgcct gtctatttga acgctttttc aggagaagga gtgatggttg
    17161 tgactcctaa tgagtattta tcaaagcgtg atgccgagga aatgggccaa gtttatcgtt
    17221 ttctaggatt gaccattggt gtaccattta cggaagatcc aaagaaggaa atgaaagctg
    17281 aagaaaagaa gcttatctat gcttcggata tcatctacac aaccaatagt agtttaggtt
    17341 ttgattatct aaatgataac ctagcctcga atgaagaagg taagttttta cgaccgttta
    17401 actatgttat tattgatgaa attgatgata tcttgcttga tagtgcacaa actcctctga
    17461 ttattgcggg ttctcctcgt gttcagtcta attactatgc gatcattgat acacttgtaa
    17521 caaccttggt cgaaggagag gattatatct ttaaagagga gaaagaggag gtttggctca
    17581 ctactaaggg ggccaagtct gctgagaatt tcctagggat tgataattta tacaaggaag
    17641 agcatgcgtc ttttgctcgt catttggttt atgcgattcg agctcataag ctctttacta
    17701 aagataagga ctatatcatt cgtggaaatg agatggtact ggttgataag ggaacagggc
    17761 gtctaatgga aatgactaaa cttcaaggag gtctccatca ggctattgaa gccaaggaac
    17821 atgtcaaatt atctcctgag acgcgggcta tggcctcgat cacctatcag agtcttttta
    17881 agatgtttaa taagatatct ggtatgacag ggacaggtaa ggtcgcggaa aaagagttta
    17941 ttgaaactta caatatgtct gtagtacgca ttccaaccaa tcgtccgaga caacggattg
    18001 actatccaga taatctatat atcactttac ctgaaaaagt gtatgcatcc ttggagtaca
    18061 tcaagcaata ccatgctaag ggaaatcctt tactcgtttt tgtaggctca gttgaaatgt
    18121 ctcaactcta ttcgtctctc ttgtttcgtg aagggattgc ccataatgtc ctaaatgcta
    18181 ataatgcggc gcgtgaggct cagattatct ccgagtcagg tcagatgggg gctgtgacag
    18241 tggctacctc tatggcagga cgtggtacgg atatcaagct tggtaaagga gtcgcagagc
    18301 ttgggggctt gattgttatt gggactgagc ggatggaaag tcagcggatc gacctacaaa
    18361 ttcgtggccg ttctggtcgt cagggagatc ctggtatgag taaatttttt gtatccttag
    18421 aggatgatgt tatcaagaaa tttggtccat cttgggtgca taaaaagtac aaagactatc
    18481 aggttcaaga tatgactcaa ccggaagtat tgaaaggtcg taaataccgg aaactagtcg
    18541 aaaaggctca gcatgccagt gatagtgctg gacgttcagc acgtcgtcag actctggagt
    18601 atgctgaaag tatgaatata caacgggata tagtctataa agagagaaat cgtctaatag
    18661 atggttctcg tgacttagag gatgttgttg tggatatcat tgagagatat acagaagagg
    18721 tagcggctga tcactatgct agtcgtgaat tattgtttca ctttattgtg accaatatta
    18781 gttttcatgt taaagaggtt ccagattata tagatgtaac tgacaaaact gcagttcgta
    18841 gctttatgaa gcaggtgatt gataaagaac tttctgaaaa gaaagaatta cttaatcaac
    18901 atgacttata tgaacagttt ttacgacttt cactgcttaa agccattgat gacaactggg
    18961 tagagcaggt agactatcta caacagctat ccatggctat cggtggtcaa tctgctagtc
    19021 agaaaaatcc aatcgtagag tactatcaag aagcctacgc gggctttgaa gctatgaaag
    19081 aacaaatccg tgcggatatg gtgcgtaatc tcctgatggg gctggttgag gtcactccaa
    19141 aaggtgaaat cgtgactcat tttccataag aggagaaaat atgacaattt acaatataaa
    19201 tttaggaatt ggttgggcta gtagcggtgt tgaatacgct caagcctatc gtgctggtgt
    19261 ttttcggaaa ttaaatctgt cctctaagtt tatctttaca gatatgattt tagccgataa
    19321 tattcagcac ttaacagcca atattggttt tgatgataat caggttatct ggctttataa
    19381 tcatttcaca gatatcaaaa ttgcacctac tagcgtgaca gtggatgatg tcttggctta
    19441 ctttggtggt gaagaaagtc acagagaaaa aaatggcaag gttttacgtg tattcttttt
    19501 tgaccaagat aagtttgtaa cctgttattt ggttgatgag aacaaggact tggttcaaca
    19561 tgccgagtat gtttttaagg gaaacctgat tcggaaggat tacttttctt atacgcgtta
    19621 ttgtagcgag tattttgctc ccaaggacaa tgttgcagtc ttataccaac gaacttttta
    19681 caatgaagac gggactccag tctatgatat tttgatgaat caagggaagg aagaagttta
    19741 tcatttcaag gataagattt tctatggaaa gcaagctttt gtgcgtgcct ttatgaaatc
    19801 tttgaatttg aacaagtctg atttggttat tctggatagg gagacaggta ttggacaggt
    19861 tgtgtttgag gaagcacaga cagcacatct agcggtagtt gttcatgcgg agcattatag
    19921 tgaaaatgct acaaatgagg actatatcct ttggaataac tattatgact atcagtttac
    19981 caatgcagat aaggttgact tctttatcgt gtctactgat agacaaaatg aagttctaca
    20041 agagcaattt gccaaatata ctcagcatca gccaaagatt gttaccattc ctgtaggcag
    20101 tattgattcc ttgacagatt caagtcaagg gcgcaaacca ttttcattga ttacggcttc
    20161 acgtcttgcc aaagaaaagc acattgattg gcttgtgaaa gctgtgattg aagctcataa
    20221 ggagttaccg gaactaacct ttgatatcta tggtagtggt ggagaagatt ctctgcttag
    20281 agaaattatt gcaaatcatc aggcagagga ctatatccaa ctcaaggggc atgcggaact
    20341 ttcgcagatt tatagccagt atgaggtcta cttaacggct tctaccagcg aaggatttgg
    20401 tctgaccttg atggaagcta ttggttcagg tctacctcta attggttttg atgtgcctta
    20461 tggtaatcag acctttatag aggatgggca aaatggttat ttgattccaa gttcatctga
    20521 ccatgtagaa gaccaaatca agcaagctta tgccgctaag atttgtcaat tgtatcaaga
    20581 aaatcgtttg gaagctatgc gtgcctattc ttatcaaatt gcagaaggct tcttgaccaa
    20641 agaaatttta gaaaagtgga agaaaacagt agaggaggtg ctccatgatt gaactttatg
    20701 atagttacag tcaagaaagt agagatttac atgaaagtct agtcgctact ggtctttctc
    20761 aacttggagt ggtcatcgat gcagatggtt ttctgcctga tggtctgctt tctcctttta
    20821 cctattatct aggttacgag gatggaaaac ctctctattt taaccaagtt cccgtttcag
    20881 atttttggga aattttagga gataatcagt ctgcttgtat tgaagatgtg acgcaggaga
    20941 gggctgtcat tcattatgtt gatggaatgc aggctcgctt ggttaaacag gtagactgga
    21001 aagacctaga aggtcgagta cgtcaggttg accactacaa tcgctttggt gcttgctttg
    21061 ctaaaaccac ttatagcgca gatagcgagc cgattatgac agtttaccaa gatgtcaatg
    21121 gccaacaagt tttactggaa aaccatgtga cgggtgatat cttattgact ttgcctggtc
    21181 agtccatgcg ttactttgca aataaagttg aatttatcac cttctttttg caagatttgg
    21241 aaatagatac cagtcagctt atctttaata ctctagcgac tcctttcttg gtttccttcc
    21301 atcatccaga taaatctggc tcggatgtct tggtatggca ggaacctctc tatgatgcca
    21361 ttccaggtaa tatgcagttg attttggaaa gtgataatgt gcgtactaag aagatcatca
    21421 ttccaaataa ggcgacttat gagcgcgctt tagagttaac tgacgagaaa taccatgatc
    21481 agtttgtgca cttgggttat cattaccagt tcaaacgtga taatttccta agacgagatg
    21541 ccttaatctt gaccaattca gatcagattg agcaagtaga agcaatcgta gaagccttgc
    21601 ctgatgttac cttccgtatc gcagcagtga cagagatgtc ttctaagctc ttagacatgc
    21661 ttcgctatcc taatgtggtc ctttaccaga atgctagtcc acagaagatt caggagctgt
    21721 atcaactgtc ggatatttac ttggatatca atcacagcaa tgagttgttg caggcagtgc
    21781 gtcaggcctt tgagcacaat ctcttgattc ttggatttaa ccaaacggtt cacaatagac
    21841 tttatatcgc tccagaacat ctatttgaaa gtagtgaagt tgctgccttg gttgagacca
    21901 ttaaattggc cctttcagat gttgatcaaa tgcgtcaggc acttggcaaa caaggccaac
    21961 atgcaaatta tgttgacttg gtgcgatatc aagaaataat gcaaactgtt ttaggaggct
    22021 aacatgtcag aggaagattt attttacaaa gacgttgaag gtcgcatgga agagttgaaa
    22081 caaaaaccca tcaagaagga aaaagaaacc cgaggggaga agattagtaa aactttttca
    22141 cttttactgg gcttaatgat tctgattggt ttgctcttta ctttgttggg aattttgagg
    22201 tagatcaatg attgaaatgc taattgtttt agctattatc ctatctcttg ctttgattgt
    22261 attggtaact atacaacccc gtcaaaatca actattttcc atggatgcca ctagtaatat
    22321 tggtaaacca agctactggc agagcaacac cttggtcaag gtgctcactt tattggtgag
    22381 tttggcttta tttgttctac tattaacctt tatggtgatt acttataaat aaaagaaaac
    22441 ttcagatatt caccttttgt ggattggtct gaagttttct tttttatact caatgaaaat
    22501 caaagagcaa actaggaagc tagccgcagg ctgctcaaaa cactgtttta aggttgtgga
    22561 tggaactgac gaagtcagct caaaacaccg ttttgaagtt gtagatagaa ctgacgaagt
    22621 cagctcaaaa caccgttttg aggttgtgga tagaactgac gaagtcagct caaaacaccg
    22681 ttttgaggtt gtggatagaa ctgacgaagt cagctcaaaa catcgttttg aggttgtgga
    22741 tagaactgac gaagtcagta acatatatac agcaaggcga cgctgacgtg gtttgaagag
    22801 tattactgtc tatatttttg gtaaaaatca acttttactt ggatgaaggt tttggcttca
    22861 cgtaggagtt gaagaagggt ggcgcgggtt tcaaattctt ctcttgtctt gggcagactg
    22921 cggttccgga agacttccag ataacgttca atttcatcta gcaaatcaga agcaggattg
    22981 gtctggctca gttgacctgc aatttttgaa aagagttgcg ctaagatcag gctttcactg
    23041 gcggcaaggt gacaagtgtt aatctgttgg gccatgtttc tcaggatacg actttgtcgt
    23101 tgtctcatct caaagtagtg gatatggtag tcggtctggt gaaagaggtg gtcagagtga
    23161 tccaaataga ccagtctgag ggcttctttc aaaagcgtgt ctaattctgc taccagctgt
    23221 gctcggttgc gtccgtctcc tctggataaa tagtatttga agcgctggag gatatctttt
    23281 aacttttctt ccaccagcgt gtggtagtgc tggatttcct cttctcgtga aggcatatag
    23341 agattaacaa gcaaggcaaa tcctgtaccg atagcaaaga gaaggaattc gttgactagg
    23401 aggtctggag aggttgactc ttgaaccaag agatggctaa ccaaaaccgt gcttggtgtg
    23461 atgccaattt cccagcccat cttgtaggct aaaggaacgt agaaggccag atagaggccg
    23521 agactccaga tatgaaatcc gctcaagtga aaagctagaa caccgatagc cagagctaga
    23581 agcatagaaa aaagacgatt gcgagccagt tttaaagtac ttctacgcgt atcagatagg
    23641 ctcaagagag cgataattcc agccgaaact gctgacgaaa gattgagaaa ataagcaaac
    23701 aggcaggcaa gacaggtagc taagatgagc ttggtcgtac gttggctaat agacataaga
    23761 atttcctaat aagttagaat aaaagcgtaa aagacaagac atgagcaggc ttgccttgat
    23821 gagttatttt ttacgggttg ctgcgtattc ggcaacggcg gtaaagagga catctgtaga
    23881 agagttaagg gctgtttcac atgagtcttg gatgacacca atcacaaaac caaccccaac
    23941 aatttgtatg gcaatatcgt tagaaatacc gaaaaggcta caagcaactg ggataagaag
    24001 gagggaacct ccggcaatac ctgaagcacc acaggctgag atagctgcta ccacactgag
    24061 gacaaaggct gtggcaaagt caacaggaat tccaagagtg ttaactgtaa caagggtcaa
    24121 aaggttaatg gtaatcgcta ctccagccat attgatagta gaaccgagtg ggatagaaac
    24181 agaataggta tctgggttga gtccaaggtc atggcagagt ttcatattga caggaatgtt
    24241 agccgcagaa ctacgagtga aaaaggctgt cacaccgctg acacggaggc agttccaaac
    24301 tagagggtaa ggattgcgtc tcataaagaa gaaggcaatc aaagggttga ccacaggggc
    24361 aacaaaaagc atagtcgtta ctaatagaac caataaaata ccgtagttgg caagccttcc
    24421 gactcccttg tcagaaatgg ttttaaaaac aagaccaagg attccaaatg gagtcagatt
    24481 gatgatccat tcgacaattt tagaagtcac gtcagcgata gtttttagca attctttact
    24541 atttttactg gcttctctca tagcgattcc aaaaatgact gcccaagata agattccaat
    24601 atagttagca gtaagcaggg cgttgactgg gctgtcaacc agtttgagca agaggttgct
    24661 gaggacctgc ccaatcccat ctggtggtgc aatttcagta ttggcactat ttagggtaat
    24721 ttcaataggg acgatgaaac ttgctagtac agctacaaga gcagcggcga aagtccctat
    24781 cataggatat acaagaaaac aacagttttc atattgctat cttgtccctt ttgatgttgg
    24841 gaaagggcat tggcaacgag agcaaagact aggataggag caacagcttt tagacctcca
    24901 acgaataaat ccccgagtag cccaatccct gagagattag gaagggtcag tcctaggatt
    24961 ccccacaaag cataccaatc aagatacgct tgacaaggct tgccttattc caagcatgaa
    25021 tgattctttt cataataatc tcctttttgt gtagtgatta tgattatagt ataaatgata
    25081 gacaaaatca agaattttct gtctattttt tgaatattta tggagaatga gactgatgaa
    25141 aatatggtat aatgaaataa aggagtttta tatgcaaaaa tttattcagg cttatattga
    25201 aaagctagat gtgacaacca ttatcgagaa tattctaacc aaggtcattt ctcttttact
    25261 gcttttgatt gtattttata ttgctaaaaa aatgcttcat accatggtgc agagaattgt
    25321 caaaccttct ctaaaaatgt ctcgtcatga tgtcggacgc caaaaaacca tctcacgttt
    25381 actagaaaat gtgtttaatt atacgctata tttcttttta ctctactgca ttttgtcgat
    25441 tttaggtttg ccagtttcta gtttgctggc tggagctggt attgctgggg tagcgattgg
    25501 tatgggagcc caaggctttc tgtctgatgt catcaatggc tttttcatcc tctttgaacg
    25561 tcaactggat gtgggagatg aggtcgttct gacaaatgga ccgattactg tatcgggtaa
    25621 ggttgtcagt gtgggaattc gtacgacaca gcttcgtagc gaggagcaag cccttcactt
    25681 tgtccctaac cgaaatatca cagttgttag caatttctca cgcacagact agacctgtta
    25741 ttttaagtaa tttgtggtac aatagaggga gtttaataag gagaaaagat ggttttagaa
    25801 aagcagttgg gccatggttg tacctggata gacctagacc taggaaagtt gaataaacta
    25861 gaagaccttt ctgaaattta cggtttggac aaggaaacca ttgaatacgc actggataga
    25921 aacgagcgcg cccacatgga ctaccaccgt gaaagtggga cggttacctt tatctataat
    25981 gtcctagacg taaaaaagga caaggcctac tatgagactt ttcccatgac ctttatcgtc
    26041 gagcatcgtc gcctgattac cattagtaat accaagaacg cctatgtcat tgaacagatg
    26101 actcgttatc tggagagcca tgacacgctt tcgatttata agtttctctt tgccagtctg
    26161 gaaatcatca gcaatgccta ctatcctgtc attgagcaga tggacaagag tagggatgag
    26221 gtcaatgacc tcttgcgcca gcgaactacc aagaaaaacc tctttgccct gtctgatttg
    26281 gagactggta tggtttatct gacggcagct gccaaacaaa atcggatttt gttagagcat
    26341 attcaaggtc atgccttgta tcgtagtttt gatgagattg agagagaaca gtttgatgat
    26401 gccatgattg aggctcatca gctggtatcc atgacagacc taatctctca gattttacag
    26461 cagctttcag cctcttacaa caatattcta aacaataatc tgaatgacaa tttgacaacc
    26521 ttgactatca tttcagtctt gctagctgtt ttggcagtcg tgacaggctt tttcggaatg
    26581 aatgttccct tacctttaac agatgagccc catgcttggc tctatatcag tttggctagt
    26641 gcaggtttgt ggattgtttt atccttgtta ctaaggaaaa ttgcgaaaaa aagttaagaa
    26701 aaggagccag aatggcgatt gaaaattata taccagattt tgctgtggaa gcagtctatg
    26761 atctgacagt cccaagcctg caggcgcagg gaatcaaggc tgttttggtc gatttggata
    26821 ataccctcat tgcttggaac aaccctgatg gaacgccaga gatgaagcaa tggctacatg
    26881 accttcggga cgcgggtatt ggcattatcg tagtgtcaaa taacaccaaa aaacgcgttc
    26941 aacgagcagt tgagaaattt gggattgatt acgtttactg ggccttgaag cccttcacat
    27001 ttggtattga ccgtgccatg aaggaattcc actatgacaa aaaggaagtg gtcatggttg
    27061 gcgaccagct catgacagat atacgagcag cccaccgtgc agggattcgg tcaattttag
    27121 tcaaaccctt ggtccaacat gactcaatca aaacgcagat taaccgaact cgtgagcgtc
    27181 gtgttatgag aaaaatcact gaaaagtacg gaccgattac atataaaaaa ggaatttaac
    27241 tatggaagaa attctctgta ttggttgtgg agcaaccatt cagacgacag ataaagctgg
    27301 tcttggtttt accccccagt cggcacttga aaaaggtttg gagactggcg aagtctattg
    27361 ccaacgctgt ttccgtctcc gccactacaa tgaaatcaca gatgtccagt tgacgaacga
    27421 tgatttcctc aagctcttgc acgaggtggg agacagtgat gccttagtgg tcaatgtcat
    27481 tgatatcttt gattttaatg gatctgtcat cccaggttta ccacgtttcg tctcgggcaa
    27541 tgatgtcctc ttggtaggaa ataaaaaaga tatccttcct aagtcagtta agtctggtaa
    27601 gattagccag tggctcatga aacgtgccca tgaagaaggt cttcgtccag tcgatgtggt
    27661 cctaacttca gcacaaaata aacatgccat taaggaagtc attgataaga ttgaacacta
    27721 ccgtaagggc cgcgatgtct atgtggtcgg tgtgaccaac gttggaaaat caactctaat
    27781 caatgctatt atccaagaaa tcacgggtga tcagaatgtc atcactactt cacgcttccc
    27841 agggacaacc ttggacaaaa tagagattcc gcttgacgac ggatcttata tttacgatac
    27901 gccgggaatt atccaccgcc accagatggc tcactacttg acggccaaaa acctcaagta
    27961 tgtcagtcct aaaaaggaaa tcaagcctaa gacctatcag cttaatcctg agcaaaccct
    28021 atttttaggt ggtttgggac gctttgactt tatagcagga gaaaagcaag gatttactgc
    28081 tttctttgat aatgaactca aactccatcg tagcaagctt gaaggagcta gtgctttcta
    28141 cgataagcac ctgggaactc ttctgacacc accaaatagc aaggaaaaag aagatttccc
    28201 aaggctagtc cagcatgtct ttaccattaa agataagaca gacctagtca tttcaggcct
    28261 aggctggatt cgtgtaacag gcacagcaaa agtcgccgtc tgggcaccag aaggcgtcgc
    28321 cgtcgccaca cgaaaagcaa ttatttaaaa caaaatcgct gagcgaacaa agtgagctca
    28381 tatagcgata gttattgccg tggtgtgatt gccaatctgt agattggcaa ggggcacaat
    28441 tgagaccaag gctcaattgt gaggtcagga aatccatttt tcaaagatga aatctttgga
    28501 aaattagttc cgaccgtccc tcaccaccta aaataactat caaaaaacaa ggaagaaaat
    28561 tatgtcatta gcatcaaaac aacgtgcctt cctcaacagc caggcacaca ccctcaaacc
    28621 tatcatccaa atcgggaaaa atggactcaa cgaccaaatc aaaaccagcg tccgtcaagc
    28681 tcttgatgcg cgtgaattaa tcaaggttac tctcttacaa aacacagatg aaaacatcca
    28741 cgaagtagct gaaattttgg aagaagaaat cggtgtggat acagtccaaa aaataggacg
    28801 catcttgatt ttgtttaagc aatctagcaa gaaagaaaat cgcaagattt ctaagaaagt
    28861 caaagaaatc taagaccgaa actccaaata actgttttta tagagaaata aaggggacta
    28921 gcctatgaca atcgaactat tgactccctt taccaaggta gagttggagc cagaaatcaa
    28981 ggagaaaaaa cgcaaacaag ttgggatttt aggggggaat tttaaccctg ttcacaatgc
    29041 ccatctcatt gttgcggatc aagtacggca acagttggga ctggatcaag ttcttctcat
    29101 gcctgaatac caacctcctc acgttgataa aaaggaaacc atccctgaac accatcgtct
    29161 caagatgctt gagttggcaa ttgagggaat tgacggccta gtcattgaaa ccattgagtt
    29221 ggagcgcaag ggtatttcct acacctacga caccatgaag attttgacag agaagaatcc
    29281 agatacggat tattacttta tcatcggtgc cgacatggtt gactatctgc ctaagtggta
    29341 ccgaattgat gaactggttg acatggttca gtttgtgggg gttcagcgtc cacgctacaa
    29401 ggtagggact tcctatccag ttatctgggt ggacgtaccg ctcatggata tctcgtccag
    29461 catggtgcgg gacttccttg cccaaggtcg gaaacccaac tttctcctac ctcagccagt
    29521 gctagactac atcgagaagg aggggctcta ctgatgtcct atcaagacta tatcaactgc
    29581 tcccgtgagg ccttgttgga aaaaatggca gagtttctac ctgagaaacg tctaacccat
    29641 tgtctaggtg tggagcgtgc cgctatggaa ttagctcagc gctttggtgt agatgttgag
    29701 aaagcaagtc tagcaggtct tcttcatgac tatgctaaaa agttgtcaaa tcaggaattt
    29761 ctagccttga ttgaccgtta ccagctagac cctgacctca aaaactgggg caataatgtc
    29821 tggcatggta tggtcggaat ttacaaaatt caggaagatt tggatttgca tgattcagaa
    29881 atcctgcgag ccattgaagt ccatacagtc ggtgctggtc aaatgacaga cctagataag
    29941 gtcatctacg tcgcagacta tatcgagcac aatcgagcct ttcctggagt agatgtggcg
    30001 cgtgagattg caaatctatc gctcaataag gcggtggcct acgaaacagc tcgtaccgtg
    30061 gagtatctag ctcatcaggg attccccatc tatccccaaa cccttgaaac ctataacgcc
    30121 tttgtgcact atttgaaaga gaactaaatg aagacggctt ttataatcat tgatgttcag
    30181 aatattttag tagaaactgg gttccagaca aaaagtctat tgggaaaaat ttcttattta
    30241 caaaaccagg ctagaagcaa gaatattgaa attatctatg ttcaacatat tgagaactct
    30301 gaagctcaaa catcagaaga ttggcagtta tctgcgcttt taaatcgaaa acctgctgaa
    30361 aaggtctttc agaagaagta taacagtatt ttcaaagaaa ctggcttaaa agaatacttg
    30421 gataagcagg ggattgaaaa attagtttta tgtggtatgc agacagaata ttgtgtggat
    30481 acctctgtca aggttgcctt tgaatatggc tatcagctta ttgttccaga aggtgctgtc
    30541 acaacctttg atggggatga cattccagca gaaacgatta atgaatttta tgaggacatt
    30601 tgggaggagc gctttgcaga tgttctagat tacaaacata ttttctaaaa agaggattaa
    30661 atgaacgaaa aagaattact agaactagtc gtgaaagcgg ctgatgagaa acgtgcggag
    30721 gatatcctcg cacttgatgt acaagatttg actagtgtga cggactactt tgtcatcact
    30781 agctcaatga atagccgtca gttggacgct atcgcagcta atatccgtga aaaagtagct
    30841 caagcaggct ttaaaggtag ccatgtcgaa ggcgatgcag ctggaggctg ggtcttactg
    30901 gaccttggtg ctgttgtcgt gcatatcttt tcagaagaaa tgcgtgccca ttataatcta
    30961 gagaagctat ggcatgaggc gaattcagta gatatttcag aagctcttgc ttagaagatg
    31021 aactcagttg tagtcaactg ggtttctttg cttattttag aaaaattgat agaaaggtaa
    31081 agggcctcgt gtttgtttca tttcgaaact gaacacgagc taaaagctga gataaaaagt
    31141 aactttcttt gtatctgacg atagggaaga aagtttccta tgtactcttt gcttttaagg
    31201 ctctttgtat cttagaaagg atttgaaccc gtcctgtaat tctcggaaaa tagatagcct
    31261 tccttggagc tcggctccat cgtaaggctc ctaattttct atcgaattac gggcggactt
    31321 ggtatcatgt tttatggcga cttatgaaac ctttgcggcg gtctatgatg cggtcatgga
    31381 cgatagttta tacgacaaat ggacgaattt ttctctgcgt catttgccta agaccaagga
    31441 gagaaagaaa ctcttggaat tggcttgtgg gacaggaatt caatcagtgc gcttttctca
    31501 ggctggtttt gatgtgactg gacttgactt gagtgcggat atgttgaaga ttgcggagaa
    31561 gagagcaact tcagccaagc aaaagattgc ttttatagaa ggtaatatgc tgaatttgtc
    31621 caaggcaggg aaatacgatt ttgtcacgtg ttattcggac tctatctgct atatgcagga
    31681 tgaggtggaa gtaggggacg tctttaagga cgtgtacaat gcgctgaatg aagagggagt
    31741 tttcatcttt gacgtgcact cgacctacca gacagatgaa gtattccctg gctattccta
    31801 ccatgaaaat gcggaagatt ttgccatgct ttgggataca tatgaggacg aagttcctca
    31861 ctccatcgtg catgagctga ctttctttat caaggaggct gacggttcct ttagtcgcca
    31921 cgatgaagta catgaggaga ggacctatga gatcttgacc tatgatatct tgctggaaca
    31981 ggctggattt aagtccttca aactctatgc agactttgag gataaggagc caacagaaac
    32041 tagcacccgt tggttttttg tggcgcagaa gtaggagatt agcatgacca taacaggtat
    32101 tatcgcggag ttcaatcctt ttcataatgg ccataaatac ctgctggatc aggcagaggg
    32161 actgaaaatt gttgccatgt cagggaattt catgcagcgt ggagagcctg ctattgtgga
    32221 taagtggaca agggcccaga tggcgctgga aaatggcgca gacttggtag tggaattgcc
    32281 ctttttagtc agtgttcagg cagctgattt ctttggtcaa ggagctgtgg atatcttgga
    32341 tcgcttgggc attgatagtc tagtttttgg gacagaggaa gttctggatt accagaaaat
    32401 cgctgactta tacacagaga aaggtgctga gatggagaaa tttgtgaaaa atctgcctga
    32461 ttccctttcc tatccccaga aaacccaagc tatgtggaag gaatttgctg gtcttgattt
    32521 ttcaggtaat acccccaatc atgttcttgc tctggcctat gccaaggcgg ttgcaggacg
    32581 aaatatcaag ctgcatccga ttcagcgtca gggggcaggt taccattctg tgaataaaga
    32641 tgtggacttt gcctcggcga cagccctccg tcaacatcag aaggaccaag atttcttaga
    32701 acgttttatg ccttctgttg ccctatttga gcaggccagt aaggtgatct gggaagacta
    32761 ttttcccttg ctccgctatc aaatcttgtc aaatcccgac ctaaccacca tctatcaggt
    32821 caatcaagaa atggctgtgc gcattaaaga agctattaaa acagcccagt ctgtggaaga
    32881 attggtcgag ttagtgacta ccaaacgtta caccaaggcg cgtgtcagac gcctattgac
    32941 ctatattttg gtacaggcta gagaaaatgt cttgccagaa gccattcatg tccttggatt
    33001 tactgaaaaa gtcaggcaac atctcaagtc tctgaaagga caggtcaatc tagtcagccg
    33061 aattggcaaa gaaccttggg atgctatgac ccaaaaagca gaccagattt accaactagg
    33121 gaagccaagt atagcagagc aaaattttgg aagagtgccg attagaatag aaacaaacta
    33181 agtctaccga aaggtaggct ttttgagatt ttttacgaat aatactcttc gaaaatcaaa
    33241 ttcaaatcgc gtcaacgtcg ccttgccgta ctcaagtaca gcctgcggct agtttcctag
    33301 tttgctcttt gattttcatt gagtataaat agatagaaaa gaaaatcttg tacaagttcc
    33361 tgacaatttc tttcttttcg tgtataatag tggaaaagag ctaaaacgag gtatggttat
    33421 ggaagcagtc ctttactcaa cattccgaaa tcatttaaag gactacatga agaaggtaaa
    33481 tgatgaattt gagcctttga cggtggtcaa taaaaatcca gatgaggaca ttgtagttct
    33541 ttcaaagagc gaatgggaca gtattcagga aaccctgaga atcgcccaaa ataaggagtt
    33601 atcagacaag gttttgcgag gaatggctca agtccgtgct ggaagcactc aggtccatgt
    33661 gattgaggag tgatgaatgc tactcaagtt tacagaagat gcctgggcag attattgcta
    33721 ctgacaaaac caagataaaa aaacactaaa aagaatcaat aaattaatca aggatattca
    33781 acgcgatcca tttacaggaa taggaaaacc agagccactc aaatatgatt accaaggagc
    33841 ctggtcacgg cgtattgatg cagaaaatcg cttgatttat atgatggatg gagatagcgt
    33901 ggctttcttg tcctttaaag atcattacta agtctactgc aaagtaggct ttttctcaag
    33961 tctctactaa actactattt ctaaacaaca agtttatttt ggtaaatgtg ttccaaattc
    34021 cccaaaacat attctatttt aggtttgtga aaatcacttt tttatggtag aatgtaaaag
    34081 aatgtatgtc attcggaata acaataaaat gaggtaaaaa catggaaatc atgtcgcttg
    34141 cgattgctgt ttttgccgtc atcattggtt tagtcattgg atatgtcagc atctcagcta
    34201 agatgaaatc atctcaggaa gctgcagagt tgatgctttt aaatgctgaa caagaagcaa
    34261 ctaatttacg tggacaagct gagcgtgaag cggatttact tgttaatgaa gccaaacgtg
    34321 aaagcaagtc tcttaaaaaa gaagcactat tggaggccaa agaagaagcc agaaaatacc
    34381 gtgaagaagt ggacgctgaa ttcaaatcag aacgtcaaga actcaaacaa atcgaaagtc
    34441 gtttgacaga gagagctact agccttgacc gtaaggacga caatttgacg agtaaagaac
    34501 aaacacttga acaaaaagaa caaagtattt ctgatagagc gaaaaacctt gatgcgcgtg
    34561 aagagcaatt agaggaagtc gaaagacaaa aagaagcaga actagagcgt attggtgctc
    34621 tgtctcaggc agaagcacga gatattatct tggctcagac agaggaaaac ttgaccaggg
    34681 agattgccag tcgcattcgc gaagctgagc aagaggtcaa ggaacgttct gacaaaatgg
    34741 ccaaggacat cttggttcaa gctatgcaac gtatcgctgg tgaatatgta gcggagtcaa
    34801 caaactcaac agttcatctg ccagacgata ctatgaaggg acgcattatt ggtcgtgaag
    34861 gtcgtaacat tcgtaccttt gaaagtttga caggggtcga tgtgattatc gacgatacac
    34921 cagaagtggt gaccttgtca ggatttgatc cgattcgtcg tgagattgcc cgtatgacta
    34981 tggaaatgtt gctcaaagat ggtcgtatac atccagctcg tatcgaagag ttggttgaga
    35041 aaaaccgtca agagattgac aataagattc gtgaatacgg tgaggctgct gcctatgaaa
    35101 ttggtgcgcc aaaccttcat ccagacttga tgaagattat gggacgtttg cagttccgta
    35161 cttcatatgg acaaaatgtt ttgcgccatt cgattgaggt tgctaagttg gctggtatca
    35221 tggcgagcga acttggtgaa aatgcggctc ttgcccgtcg tgctggattc cttcacgata
    35281 tcgggaaagc cattgaccat gaggttgaag gtagccacgt tgaaatcggt atggaattgg
    35341 cccgtaagta caaggaaccc ccagttgtgg tgaatacgat tgctagtcac cacggagatg
    35401 ttgaagctga gagcgtgata gcagttatcg tcgctgcagc agatgccttg agcgcagccc
    35461 gtccaggtgc tcgtagtgag tctcttgaaa gctacatcaa gcgtctccat gatttggaag
    35521 aaattgctaa cggctttgaa ggagtgcaaa ctagctttgc ccttcaagca ggacgtgaaa
    35581 ttcgtatcat ggtcaatcca ggaaaaatca aggacgacaa agtcacaatc ttggctcaca
    35641 aagttcgtaa gaaaattgaa aacaatctcg attatccagg aaatatcaag gtaaccgtga
    35701 ttcgcgagct tcgtgcagta gattatgcta aataaataag aaagagcagt tgaaaaatta
    35761 ctgctttttt gttacactag atagaaagac tgtaaaggat aatctggctt tttgccatta
    35821 ttctagagaa atgttatttc acagattgac taaaaggaga cacaatggca gaccgaggct
    35881 tactaatcgt tttttctggt ccttcagggg ttggaaaagg aacggttaga agagagattt
    35941 ttgagagttc tgaaaaccaa tttcaatatt ctgtatcgat gacgacacgc gcacaacgtc
    36001 ctggagaagt ggacggtgtt gactatttct tccgtactcg tgaagaattt gaagagctga
    36061 ttcgtcaagg acagatgttg gaatacgcag aatatgtcgg caactactat ggaactcctc
    36121 tgacctatgt caatgaaacc ttggacaagg gaatcgatgt tttccttgaa attgaagttc
    36181 agggtgctct tcaggtcaag aaaaaggttc cagatgctgt ctttatcttc ctgacaccac
    36241 cagatttgga tgaattgcaa gatcgcttgg taggtcgtgg aacagatagt gcagaagtga
    36301 ttgcccaacg aatcgaaaag gccaaggaag aaattgccct catgcgtgag tatgattatg
    36361 cgattgtcaa cgatcaggtg cccctagctg ctgaacgtgt caaatgtgtg attgaagcag
    36421 aacacttctg tgtggatcgt gtcattggtc actatcagga gatgttacca aaatctccaa
    36481 ctacccgata aaatttagaa aataggtaca agcaaatgat gttaaaaccc tctattgata
    36541 ccttgctcga caaggttcct tcaaaatatt cactcgtaat cttggaagca aaacgtgccc
    36601 acgaattgga agcaggtgcc ccagcaactc aaggtttcaa gtctgaaaaa tcaactcttc
    36661 gcgctttaga agaaatcgaa tcaggaaacg ttacaattca cccagatcca gaaggaaaac
    36721 gtgaagcagt gcgtcgccgt atcgaagaag aaaaacgccg caaagaagaa gaagaaaaga
    36781 aaatcaaaga gcaaattgct aaagaaaaag aagatggtga aaaaatttaa ggttgggggg
    36841 actcaatctt attttttcta ttgcaagaat gtactgacaa ggaggaggtg agaagatggc
    36901 cctagctaag attatcgtag atgtgccctt gatgcagacg gaccagccct atagttacag
    36961 gattccggag gaatttgagg gaatgctgga agttgggatg cgggttcatg tgccttttgg
    37021 taagggtaat cgcctgattc aagggattgt tcttggtttg aagtcccaat cagatggaga
    37081 agagatggag caagatttaa aagatattgc agaggtgctg gatttttctc ctgttctcac
    37141 gccagaacaa ctctggctgg ctgaggagtt acgcaaatct gtcttctcct acaaaatctc
    37201 tatcctcaag gccatgcttc cagggtttct gaattctagc tatgacaaga ttctctatcc
    37261 tctggaaggc ttgagtcagg aagaacgagt acgcctgttt ggttcagaag attcgctagc
    37321 cttttcttca ctagaccttg ccaagcaagc tgaaatgatg cgtttgacta gaaaaggcct
    37381 gcttggtctg gaatatcagg cagtcgatca aaagaaggtc aagacccagt cttggtatga
    37441 ggttgaccat gcccaattag aaggtgttga gatttctaca cgtgccaaga aaaagttgga
    37501 actgagagat tatctgctgt ctcatccaga gagcgcttcc ttggctagct tgttagagtc
    37561 ctactcgcga gagcaagtca acttctttgt ggatcaaggt actgttacca tagtccaaaa
    37621 ggaagttcaa cgctcggctg cttattttga aggaattgaa gcaagtagac ctttggagtt
    37681 aaatccagaa caaagacagg cgcgtgatgc ggttgtgagt tctattggca gttctcaacc
    37741 tccctttcta cttcaaggga ttacaggaag tgggaagacc gaggtttact tgcagattat
    37801 ccaaggtgcc ctggataagg gtaagacagc tattttgctg gtacctgaga tttccttgac
    37861 tcctcagatg accgagcgtt ttatagcacg ttttggggac aaggtagcca ttcttcactc
    37921 aggattatcc aatggcgaaa agtatgatga atggcgcaag gtggagcgtg gcgatgccca
    37981 agttgttgtt ggtgccagat ctgctatctt tgctcctctg aaaaatctgg gtgtcatgat
    38041 tattgatgaa gagcatgaag cggcttataa gcaggacagc aatccccgtt accatgccag
    38101 agaggtagct attttacggg ctcagtataa tcaagcaact ctggtacttg gatctgcaac
    38161 gccgagctta gagagccggg cacgtgctgg caaaggcgtc tatcaacact tacgtctaac
    38221 ccaacgtgcc aatcctttgg ctacaatccc tgaggttcaa gtgattgact ttcgagacta
    38281 tatcggacaa aatgagacgt caaactttac gcctcctttg ctagaggcta tccaagaccg
    38341 tctggttaaa aaagagcagg tggttctcat gctcaatcgc cgtggttatt ctagctttgt
    38401 catgtgtcgg gagtgtggga cggtggatac ttgtcccaac tgcgatattt ctctgacctt
    38461 gcatatggat accaagacta tgaactgcca ttattgtggt ttctcgaagg atattcctca
    38521 ggtctgtcct aactgtaaga gccgcagtat tcgttactat gggacgggaa ctcagaaggc
    38581 ttatgatgag ctagcagaac tctttcccca agctcgcatt ttgaggatgg atgtggatac
    38641 gactcgaaag aaaggcagtc accaagcctt gcttgaccag tttgggcgag gggaagcgga
    38701 tattttactt ggtactcaga tgattgcaaa gggtttggat tttcccaatg ttaccctagt
    38761 cggagttcta aatgcggata cggccttgaa tctgcctgat ttccgttctt ctgagagaac
    38821 cttccagctc ttgactcagg tggcaggtcg agcaggtcgg gctgaaaaag caggtcaagt
    38881 cttgatacag tcctacaatt cgcagcacta tgctattcga tttgccaagg atcaagatta
    38941 cgaaggcttt tatgcctatg aaatgggaat cagacgacaa ctcggctatc caccttacta
    39001 tttcacgatt ggtattaccc tttctcacaa gaaagaagaa gaggttttca aacgtgccta
    39061 tgaagtcatg aacattttgc ggtcaggctt gtcagagacc agtcccattc tggggccaac
    39121 gccaaaaccg attgcccgta cccacaacct ctatcattac cagattttaa ttaaataccg
    39181 tttagaagat gagctggggc cgaccctcaa ccaggtcttg gccttgactc aagaacggga
    39241 aaatagtgag ctccgtctca gcattgacca tgagccgcag caatttttat aagaaggaga
    39301 agatatgaca aaactaatct ttatggggac ccccgacttt tcagcaacag tcttaaaagg
    39361 acttttgaca gatgaccgtt acgaaattct agccgttgtg acccagccag accgtgctgt
    39421 tggtcgtaaa aaagttatcc aagaaacccc agtcaagcag gctgccaagg aagcaggact
    39481 atctatctac caacctgaaa aattatctgg aagtccagag atggaagaac ttatgaagct
    39541 aggagcagat ggaattgtga ctgctgcttt tgggcagttt ctcccaagca aactccttga
    39601 tagcatggac tttgctgtca acgttcatgc ctccctcctt cctagacacc gtggtggtgc
    39661 gcctatccat tatgccttga ttcaagggga tgaggaagct ggtgtgacca tcatggaaat
    39721 ggttaaggaa atggatgcag gagatatgat ttctcgtcgc agcattccga tcacagatga
    39781 ggacaatgtt ggcaccttgt ttgaaaaatt ggcgctagtt ggtcgtgatt tgcttttgga
    39841 cactctgcct gcctatattg ctggtgatat caaacctgaa ccgcaggata cgagtcaggt
    39901 taccttctct ccaaatataa agccagagga agaaaaactg gactggaaca aaaccaatcg
    39961 tcaactcttt aaccaaattc gtggaatgaa cccctggcct gttgcccata ctttccttaa
    40021 gggcgaccgc tttaagattt atgaagccct accagtagaa ggtcagggaa atccaggtga
    40081 gattctctct atcggcaaga aagaattgat tgtcgcaacg gctgaagggg ctctatccct
    40141 caaacaagtg cagccagctg gtaagcctaa gatggacatt gcttccttcc tcaatggagt
    40201 tggacgtaca ttgactgtag gagaacgatt tggtgactaa agtagaaacg gctagaagtt
    40261 tagctctagc agtgctagag gatgtttttg tgaatcaagc atattcaaat attgccttaa
    40321 ataaacacct caaggggagt cagctctctg cagcagacaa gggcttagtg accgagctag
    40381 tctatggaac ggtagcccgt aaactgactc tggaatggta cctatcccac tttatcgaag
    40441 acagagacca gttagacagc tggctctatg tccttcttct catgagtgcc taccaactcc
    40501 gctatttgga caagattcca gatcatgctg tggtcaatga agcagtggaa ttggccaaac
    40561 tccgtaaaaa aggcagtgaa aaattggtca acgctgtcct tcgccgtatc ttgcgtgaag
    40621 gctggccaga tattgctagc atcaagcgaa aaaacaagcg tgactccatt gcctattctc
    40681 tcccagtttg gctagttgcc aaactcaagg aagaatacgg agaggagaga gcaaaagcca
    40741 tctttgaaag cctgttagtg cgaaacaaag ccagtattcg tgtaacagac ctaagtcgaa
    40801 aagaggaaat ccaagccttg ttggaggcga ataattccct tttagcaacc actggtctgg
    40861 ttaaggagca ggggcatttt gcagggcata atttgtttgc ggatggagcc attaccatcc
    40921 aagacgagtc cagtcagttg gttgctccga cgcttgattt acaaggtgat gagcgagtgc
    40981 ttgatgcctg tgcggctcca ggtgggaaaa cagcccatat agcctcttat cttacgacag
    41041 gtcaggttac tgctctggac ttgtacgacc acaagttgga tttaattcaa gaaaatgccc
    41101 aacgtctggg agttgaagat cgggttcaaa ctcaaaaatt ggatgccaga aaggtgcatg
    41161 agttttttga ccaggattcc tttgataaga ttttggtgga tgctccttgt tcaggaatcg
    41221 gtcttttgcg ccgaaaacca gatatcaaat acaataaaga aacggcagat ttcgcgtcct
    41281 tgcaggaaat tcagttagaa atattaggta gtgtttgtca aatactaggc aaaggtggta
    41341 taataactta tagcacctgc actatcgtct cagaggagaa ttttcaagtc gttaaggcct
    41401 ttttagagag tcatcccgag ttcgagcagg taaaactaga acatgaatgt aaggatatca
    41461 tgaaagacgg ctgtatcctc attacacctg aattgtatgg aagtgatgga ttcttcatca
    41521 gtcaatttcg caagatatcg gattaggaag gaactgacac atggaaattt cattattaac
    41581 agatgttggt cagaaacgaa caaataacca agactatgtc aaccactatg tcaatagagc
    41641 tggacgtacc atgattattt tagctgatgg gatgggaggt catcgtgcag ggaatatcgc
    41701 tagtgaaatg gcggtcacag acctgggtgt agcttgggtt gatacccaga tcgatacagt
    41761 caatgaagtg cgtgaatggt tcgcccatta cctagaaatt gaaaatcaaa agattcacca
    41821 gcttggtcag gatgaagctt acagaggcat gggaactact ttggaagtcc ttgctattat
    41881 tgataatcag gctatctatg ctcatattgg tgattcgcgt atcggcttga ttcgtggaga
    41941 agaataccat cagttgacga gcgatcattc cttggttaat gaattgctca aggctggtca
    42001 attgacacca gaagaggcag aagctcatcc gcaaaaaaat attatcaccc agtctattgg
    42061 gcaaaaagat gaaattcagc ctgattttgg gacagttatc cttgagtcag gtgactatct
    42121 cttgctcaat agtgacggct tgaccaacat gatttcaggc agtgagattc gtgatattgt
    42181 aaccagtgat attcctttag cagataaaac ggagacactt gttcgttttg ctaacaatgc
    42241 aggaggttta gacaacatta cggttgccct tgtttttatg aacgaggagg atgcagaatg
    42301 atccaaatcg gcaagatttt tgccggacgc tatcggattg tcaaacagat tggtcgagga
    42361 ggcatggcgg atgtctacct agccaaagac ttaatcttag atggggaaga agtggcagtg
    42421 aaggttctga ggaccaacta ccagacggac ccgatagctg tagctcgttt tcagcgtgaa
    42481 gcgagagcta tggcagatct agaccatcct catatcgttc ggataacaga tattggcgag
    42541 gaagacggtc aacagtacct agctatggag tatgtggctg gactggacct caaacgctat
    42601 atcaaggaac attatcctct ttctaatgaa gaagcagtcc gtatcatggg acaaattctc
    42661 ttggctatgc gcttggccca tactcgagga attgttcaca gggacttgaa acctcaaaat
    42721 atccttttga caccagatgg gactgccaag gtcacagact ttgggattgc tgtagccttt
    42781 gcagagacaa gtctgaccca gactaactcg atgttgggct cagttcatta cttgtcacca
    42841 gagcaggcgc gtggttcgaa ggcgactgtg cagagtgata tctatgccat ggggattatt
    42901 ttctatgaga tgttgacagg ccatatccct tatgacgggg atagcgcggt gaccattgcc
    42961 ctccagcatt tccagaaacc cctgccgtcc gttattgcag aaaatccatc tgtacctcag
    43021 gctttagaaa atgttattat caaggcaact gctaaaaagt tgaccaatcg ctaccgctcg
    43081 gtttcagaga tgtatgtgga cttgtctagt agcttgtcct acaatcgtag aaatgaaagt
    43141 aagttaatct ttgatgaaac gagcaaggca gataccaaga ccttgccgaa ggtttctcag
    43201 agtaccttga catctattcc taaggttcaa gcgcagacag aacacaaatc aatcaaaaac
    43261 ccaagccagg ctgtgacaga ggaaacttac caaccacaag caccgaaaaa acatagattt
    43321 aagatgcgtt acctgatttt gttggccagc cttgtattgg tggcagcttc tcttatttgg
    43381 atactatcca gaactcctgc aaccattgcc attccagatg tggcaggtca gacagttgca
    43441 gaggccaagg caacgctcaa aaaagccaat tttgagattg gtgaggagaa gacagaggct
    43501 agtgaaaagg tggaagaagg gcggattatc cgtacagatc ctggcgctgg aactggtcga
    43561 aaagaaggaa cgaaaatcaa tctggttgtc tcatcaggca aacaatcctt ccaaattagt
    43621 aattatgtcg gccggaaatc ttctgatgtt atcgcggaat taaaagagaa aaaagttcca
    43681 gataatttga ttaaaattga ggaagaagag tcgaatgaga gtgaggctgg aacggtcctg
    43741 aagcaaagtc taccagaagg tacgacctat gacttgagca aggcaactca aattgttttg
    43801 acagtagcta aaaaagctac gacgattcaa ttagggaact atattggacg gaactctaca
    43861 gaagtaatct cagaactcaa gcagaagaag gttcctgaga atttgattaa gatagaggaa
    43921 gaagagtcca gcgaaagcga accaggaacg attatgaaac aaagtccagg tgccggaacg
    43981 acttatgatg tgagtaaacc tactcaaatt gtcttgacag tagctaaaaa agttacaagt
    44041 gttgccatgc cgagttacat tggttccagc ttggagttta ctaagaacaa tttgattcaa
    44101 attgttggga ttaaggaagc taatatagaa gttgtagaag tgacgacagc gcctgcaggt
    44161 agtgtagaag gcatggttgt tgaacaaagt cctagagcag gtgaaaaggt agacctcaat
    44221 aagactagag tcaagatttc aatctacaaa cctaaaacaa cttcagctac tccttaaaag
    44281 cagatggata atcaaaatga gtaatcaatc tttgtcatga tttcatggca aagatttttt
    44341 ttgagtccgg atttgtgata gaatagaggg agttgataaa aggaggaaag catggaagaa
    44401 tcaaaagaat taaatgccgt cattgatgtg attatgctag cggggactat tctccttaaa
    44461 agtggctcag aaatccatcg tgtagaagat accatgattc gaatcgcgca ttcgcagggg
    44521 attgtggatt gcaatgtcct tgccatgcct gccgctatct ttttctctat tgaaaatacc
    44581 aatatttcgc gcatgaagcg cgtgacctcc tcttcttata acatcgaaaa agtctgcgat
    44641 gtgaaccaga tttctcgtca gctagttggg gggcagattg acttagaaac agcctttaag
    44701 caattgacgg ccttgcaagc tcaacccctt ccctatacta agttgcaggt aactctggct
    44761 gcgaccttta gtgctccttt cttttcagtt atgtttagcg gaaatatcta cgacgcactt
    44821 ggggcaggag tggcgacctt atttggtttt gccttttccc tctatgtgga aaaatttatc
    44881 cgaattccct ttgtgacagc ctttgctgga gcctttgtct ttgggataat tgcccagttt
    44941 tgggctcgct acacaggttt tccttcaacg gcagatttga ttatagctgg tgcggtcatg
    45001 ccgtttgtac caggtattgc cttgaccaat gcggtccgtg atattatgac caaccacata
    45061 aactctggta tgagtaagat gtttgaatcc ctgctcatta ccctcgcttt aggggcagga
    45121 acttctgtcg ccttggtatt gatgaactaa tatgacacta acaacctttt tattacaagc
    45181 agtagcaagt tttcttgcca ttatcacttt tttaatcgta ctcaatgtgc aacggtctat
    45241 gctcttacct ggagggattt tgggcatgac tgtctggcta atctatctct tgctcaagga
    45301 accgaccaat gtcattgtag ctaccttcat tgcagccatt attggttctt gtgtcagcca
    45361 gattttaagt attctttata agacacctgc tgtggtcttt atcttggcca ttttggcacc
    45421 gctggttcca ggttatctct cctaccgaac aactgccttt tttgtgacag gggactataa
    45481 taaagcactg gcaagtgcga ccttggttgt catgttggct ttggtaatct ctattggaat
    45541 ggctagcgga acagtgattc tcagactgta tcattatata aaaacacatc gagtatcgta
    45601 gactttacag aaataaaaga attttctgaa aaatgagata aataaattaa caacgctttc
    45661 tatatgtgcg agaataccgc acttatgaag aaattgcggc tgattttggt atccacgaaa
    45721 gcaacttact ccgtcggagc caatgggttg aagtaactct tgttcaaagg tggtgttacg
    45781 atttcaagaa ctcctctcag ttctgaagac acggtaatga ttgatgcgac ggaagtaaaa
    45841 atcaatcgcc ctaaaaaaaa caattagcga atgattctgg taaaaagaaa tt
//
LOCUS       DAVBIC010000010        45291 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.010, whole genome shotgun sequence.
ACCESSION   DAVBIC010000010 DAVBIC010000000
VERSION     DAVBIC010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 45291)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45291)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45291
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.010"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            complement(56..1066)
                     /locus_tag="VQ664_000532"
     CDS             complement(56..1066)
                     /locus_tag="VQ664_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HET2788753.1"
                     /translation="MSFLSKNGAGILACLLISIVSWYLGGFFPVIGAPVFAIFIGMLL
                     HPFLSSYKQLDAGLTFSSKKLLQYAVVLLGFGLNISQVFAVGQSSLPVILSTISIALI
                     IAYLFQRFFALDTKLATLVGVGSSICGGSAIAATAPVIDAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNEGFALFAGTAVNDTSSVTAAASAWDSLYQSNTLESATIVKLT
                     RTLAIIPITLFLSYWQSRQQENKQSLQLKKVFPLFILYFILASLLTTLLTSLGVSSSF
                     FTPLKELSKFLIVMAMSAIGLKTNLVAMVKSSGKSILLGAICWIAIILTTLGMQTLIG
                     IF"
     gene            1215..2384
                     /locus_tag="VQ664_000533"
     CDS             1215..2384
                     /locus_tag="VQ664_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET2788754.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQVISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEIFVVCDEVYSELTYTGEAH
                     VSLGTMLRDQAIIINGLSKSHAMTGWRLGLIFAPAAFTAQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            2381..3151
                     /gene="recO"
                     /locus_tag="VQ664_000534"
     CDS             2381..3151
                     /gene="recO"
                     /locus_tag="VQ664_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HET2788755.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKRMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDKRRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            3148..4140
                     /gene="plsX"
                     /locus_tag="VQ664_000535"
     CDS             3148..4140
                     /gene="plsX"
                     /locus_tag="VQ664_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HET2788756.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLAADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRAKLGALLLKDSLRGLKKQLN
                     YSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE"
     gene            4146..4379
                     /locus_tag="VQ664_000536"
     CDS             4146..4379
                     /locus_tag="VQ664_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HET2788757.1"
                     /translation="MTEKEIFDRIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQSVGDVVKIIQGK"
     gene            4425..4716
                     /locus_tag="VQ664_000537"
                     /pseudo
     CDS             4425..4716
                     /locus_tag="VQ664_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            4919..5149
                     /gene="blpU"
                     /locus_tag="VQ664_000538"
     CDS             4919..5149
                     /gene="blpU"
                     /locus_tag="VQ664_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HET2788758.1"
                     /translation="MNTKKMSQFEIMDTEMLACVEGGGCNWGDFAKAGVGGGAVRGLQ
                     LGIKTRTWQGAATGAAGGAILGGVAYAATCWW"
     gene            5864..8017
                     /locus_tag="VQ664_000539"
     CDS             5864..8017
                     /locus_tag="VQ664_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HET2788759.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPYKEQKNGLLSFIPI
                     LVKQRGLIANIVLATLLVTGINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGDMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            8030..9379
                     /locus_tag="VQ664_000540"
     CDS             8030..9379
                     /locus_tag="VQ664_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HET2788760.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAMETGASLASQNLAYSLYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSID
                     ATATKTEKGNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            9550..10257
                     /locus_tag="VQ664_000541"
     CDS             9550..10257
                     /locus_tag="VQ664_000541"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HET2788761.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNAAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIAGDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQELK"
     gene            10459..14184
                     /locus_tag="VQ664_000542"
     CDS             10459..14184
                     /locus_tag="VQ664_000542"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HET2788762.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDV
                     FDLAEDLFAPAEKHIFSEQGTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDATELEAVKNYLLNPVDSRFKDITTGIAKQEFS
                     ESDKTIPKLTFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDTFVA
                     ECNKENIDAVVVATVTEKPNLVMHWNGETIVDLERRFLDTNGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTIFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFAQFEASQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTAQLGGFVFTSPEEIAGVEKIG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVASDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEDANSTSPTLFYNDANQHVTKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            14277..15719
                     /locus_tag="VQ664_000543"
     CDS             14277..15719
                     /locus_tag="VQ664_000543"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HET2788763.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPANLDKLTGAGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     RDLKPGEIVIIDDEGIQYDSYTDDTQLAICSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSLTYLSIDGLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            15756..16778
                     /locus_tag="VQ664_000544"
     CDS             15756..16778
                     /locus_tag="VQ664_000544"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HET2788764.1"
                     /translation="MTNKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLASSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            16775..17320
                     /gene="purN"
                     /locus_tag="VQ664_000545"
     CDS             16775..17320
                     /gene="purN"
                     /locus_tag="VQ664_000545"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HET2788765.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKADYEAALVELLEEHQIALVCLAGYMKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYPEVVKALFTD"
     gene            17404..17913
                     /locus_tag="VQ664_000546"
     CDS             17404..17913
                     /locus_tag="VQ664_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HET2788766.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLIFFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEC
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            17938..19485
                     /gene="purH"
                     /locus_tag="VQ664_000547"
     CDS             17938..19485
                     /gene="purH"
                     /locus_tag="VQ664_000547"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HET2788767.1"
                     /translation="MTKRVLISVSDKADIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     DTIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVNL
                     YPFKETILKPDVTYDDAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAAN
                     GETSYETRQRLAAKVFRHTAAYDALIAEYFTAQVGENKPEKLTLTYDLKQPMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHM
                     NPCGIGQADDIETAWDYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLDGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAADKYGLTMVFT
                     GVRHFRH"
     gene            19607..20869
                     /gene="purD"
                     /locus_tag="VQ664_000548"
     CDS             19607..20869
                     /gene="purD"
                     /locus_tag="VQ664_000548"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HET2788768.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHSKLIDFAKTNDVAWTFIGPDDALAAGIVDDFNQAGLKAFGPTRAAAELEW
                     SKDFAKEIMVKYGVSTAAYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVSETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFFEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGMIKEGRPYLGVLYAGLILT
                     ADGPKVIEFNARFGDPETQIILPRLTSDFAQNITDILDSKEPNITWTDKGVTLGVVVA
                     SKGYPLNYSKGVELPVKTDGDIITYYAGAKFAENSRALLSNGGRVYMLVTTADTVKEA
                     QASIYQELSQQKIEGLFYRTDIGSKAIK"
     gene            21272..21760
                     /gene="purE"
                     /locus_tag="VQ664_000549"
     CDS             21272..21760
                     /gene="purE"
                     /locus_tag="VQ664_000549"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000805607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HET2788769.1"
                     /translation="MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTPD
                     LMFKHAEEARSRGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALFALRLLSVEDKSIADALANFAEEQGKIAEESSNE
                     LI"
     gene            21747..22838
                     /gene="purK"
                     /locus_tag="VQ664_000550"
     CDS             21747..22838
                     /gene="purK"
                     /locus_tag="VQ664_000550"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HET2788770.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPASRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDAVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKTATGGYDGHGQKVIRSEAD
                     LEAAYALADSADCVLEEFVNFDLEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLADKAKAMAVRIAEQLNLSGTLCVEMFATDDDVIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPVIKLHAPAVMLNVLGQHVEAAEQYVTENSSAHLHMYGKIE
                     AKHNRKMGHVTLFSDVPDSVDELGEGIDF"
     gene            22848..23075
                     /locus_tag="VQ664_000551"
     CDS             22848..23075
                     /locus_tag="VQ664_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HET2788771.1"
                     /translation="MIQIIVNTFIEKDKTGAVVEVLYASADQDKVQAKYEELAAQYPE
                     NYLAIYDVPLDTDLNTLDHYPSVFIEKEEFE"
     gene            23138..24436
                     /gene="purB"
                     /locus_tag="VQ664_000552"
     CDS             23138..24436
                     /gene="purB"
                     /locus_tag="VQ664_000552"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HET2788772.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEIDEIFNPVYYTKRVDDIFERLGLGD"
     gene            complement(24491..28429)
                     /gene="strH"
                     /locus_tag="VQ664_000553"
     CDS             complement(24491..28429)
                     /gene="strH"
                     /locus_tag="VQ664_000553"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HET2788773.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTPTTTEN
                     QPTIHTVSDSPQSSENRTEETPKAELQPEAPKTVETETPATDKVASLPKTEEKPQEEV
                     SSTPSDKAEVVTPTSAEKETANKKAEEASPKKEEAKEVDSKESNTDKTDKDKPAKKDE
                     AKAEDDKPETEAGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTD
                     LHLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYNDPNGNHLTESQMTD
                     LINYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKESARTVNLDNEQAV
                     AFTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYE
                     KFIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVAS
                     SKLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIP
                     IIGSMVAAWADTPSARYSPSRLFKLMRHFANANAEYFAADYESAEQTLNEVPKDLNRY
                     TAESVAAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTPEAQKEEEAKR
                     EVEKLAKNKVISIDAGRKYFTLNQLKRIVDKASELGYSDVHLLLGNDGLRFLLDDMTI
                     TANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSP
                     GHMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKI
                     FNFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYE
                     DKDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYILGQKPEDGGG
                     FLKKAIENTGKTPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFA
                     DHNKDYFRANYNALREELAKIPTNLEGYSKESLEALDAAKTALNYNLNRNKQAELDTL
                     VANLKAALQGLKPAATHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAG
                     QENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGAPVTHKGDESG
                     LAPTTEVKPRLDIQKEEIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADG
                     KEVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPKLEIPSQPAPSTAPA
                     EESKALPQDPAPVVIEKKLPETGTHDSAGLVVAGLMATLAAYGLTKRKED"
     gene            complement(28744..29460)
                     /locus_tag="VQ664_000554"
     CDS             complement(28744..29460)
                     /locus_tag="VQ664_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET2788774.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDRDH"
     gene            29808..31595
                     /locus_tag="VQ664_000555"
     CDS             29808..31595
                     /locus_tag="VQ664_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HET2788775.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRVPPEDWYHSLYNLKAL
                     GFNTVETYVAWNLHEPREGEFHFEGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPVYIEAVGRYYDQLLPRLVPRLLDNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEECGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            31592..32068
                     /locus_tag="VQ664_000556"
     CDS             31592..32068
                     /locus_tag="VQ664_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HET2788776.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            32096..33001
                     /locus_tag="VQ664_000557"
     CDS             32096..33001
                     /locus_tag="VQ664_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HET2788777.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            32988..33803
                     /locus_tag="VQ664_000558"
     CDS             32988..33803
                     /locus_tag="VQ664_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET2788778.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            33810..34214
                     /locus_tag="VQ664_000559"
     CDS             33810..34214
                     /locus_tag="VQ664_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET2788779.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIEGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
     gene            34513..35679
                     /locus_tag="VQ664_000560"
     CDS             34513..35679
                     /locus_tag="VQ664_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HET2788780.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVAKPAT
                     YLKKDVATVLVSFARSGNSPESVATVDLAKSLVDELYQVTITCAADGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTTLLVFDPTEFAVKSERFEVVSSLARKVLDKA
                     EDVKELVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTDYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVVLGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            35795..36832
                     /locus_tag="VQ664_000561"
     CDS             35795..36832
                     /locus_tag="VQ664_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HET2788781.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     SYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSIAPDGVPAKTPEAN
                     RDVVKHIYNGALLKDIFAEEDEQIQLASGLDHPFALPAGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            37040..37894
                     /locus_tag="VQ664_000562"
     CDS             37040..37894
                     /locus_tag="VQ664_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET2788782.1"
                     /translation="MTYEYKSHIYLAETALNVKDLASQTAFYQQVIGLEILSQTETES
                     ILGLGGKVLVQLIQAQESGEVREYYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEAIYLEDLEGNGIELYRDKPVSTWDIREDGRIIGVTEALAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLEDKFSVPSASWIAAGDYHHHLAVNEW
                     GGKGLASRKQGLPGLAYYVIEVAHKKELLTIAQRAQEVDAPIKWMTSSQLEITDSDGI
                     VTRIRLAR"
     gene            38044..38301
                     /locus_tag="VQ664_000563"
     CDS             38044..38301
                     /locus_tag="VQ664_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HET2788783.1"
                     /translation="MTNSKYITCLKRSEGQLCGIQKMIEGDRDCADIVTQLTAVRSSV
                     ERVIEMIITENLTECINQPLDDSEAQKERLEKAIRYLIKRK"
     gene            complement(38677..38769)
                     /locus_tag="VQ664_000564"
                     /pseudo
     CDS             complement(38677..38769)
                     /locus_tag="VQ664_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(38805..39101)
                     /locus_tag="VQ664_000565"
     CDS             complement(38805..39101)
                     /locus_tag="VQ664_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET2788784.1"
                     /translation="METSISMADFYGKYQNENLELIDVREAHEFQAGHAPGAKNLPLS
                     TLEQGYKELKPDHEYYVICQGGVRSASTCQFLISQGLTVTNVEGGMNAWPGQVE"
     gene            complement(39091..39252)
                     /locus_tag="VQ664_000566"
     CDS             complement(39091..39252)
                     /locus_tag="VQ664_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(FAD)-dependent dehydrogenase"
                     /protein_id="HET2788785.1"
                     /translation="MDKKQAYIVSCHSGLRSYIAEPILKQAGFTAQNLDGAYSLYKMV
                     NPEGVEYGN"
     gene            39322..40086
                     /locus_tag="VQ664_000567"
     CDS             39322..40086
                     /locus_tag="VQ664_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HET2788786.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLDEEI
                     DRYAREVGADCVGEFVSATKTYPVYVINYKGEEVCLAQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPSRYMEMQPEAIAAIEEVLE
                     DRGIPYEEVMTWTTDGFYRETAEKVAYRKEEGCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLDQYDSRDWGSEAFNKALELSLASVHHL"
     gene            40699..42078
                     /locus_tag="VQ664_000568"
     CDS             40699..42078
                     /locus_tag="VQ664_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HET2788787.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLI
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
     gene            42092..42757
                     /locus_tag="VQ664_000569"
     CDS             42092..42757
                     /locus_tag="VQ664_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HET2788788.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            42871..42966
                     /locus_tag="VQ664_000570"
                     /pseudo
     CDS             42871..42966
                     /locus_tag="VQ664_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            43112..43561
                     /locus_tag="VQ664_000571"
     CDS             43112..43561
                     /locus_tag="VQ664_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET2788789.1"
                     /translation="MKLLSIAISSYNAAAYLHYCVESLVIGGEQVGILIINDGSQDQT
                     QEIAECLASKYPNIVRAIYQENKCHGGAVNRGLAEASGRYFKVVDSDDWVDPRAYLKI
                     LETLQELESKGQEVDAFVTNFVYEKEGQSRKKSMSYESVLPVRQIFD"
     gene            43718..44128
                     /locus_tag="VQ664_000572"
     CDS             43718..44128
                     /locus_tag="VQ664_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HET2788790.1"
                     /translation="MYYLPVDFYRYLIGREDQSVNEQVMIKRIDQQLKVNRLLVDQLD
                     LSQVSHPKMREYLLNHIEITTVISSTLLNRSETAEHLAKKRQLWTYIQQKNPEVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
     gene            44244..>45291
                     /gene="pavB"
                     /locus_tag="VQ664_000573"
     CDS             44244..>45291
                     /gene="pavB"
                     /locus_tag="VQ664_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HET2788791.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADV
                     VNPTPGQVLPEETSGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     NSSSLDTLFEKDEEAQKNPELTDVLKETVDTADVDGTQASPAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRANGTQTYKATVKVYGNKDGK
                     ADLTNLVATKNVDININGLVAKETVEKAVKDNVKDSIDVPAAYLEKAKGEGPFTAGVN
                     HVIPYELFAGDGMLT"
BASE COUNT        12623 a         8744 c        10684 g        13240 t
ORIGIN      
        1 aacatatata cggcaaggcg acgttgacgt ggtttgaaga gattttcgaa gagtgttaga
       61 aaatgccgat aagggtctgc ataccaagag tggtgaggat gatggcaatc cagcagatgg
      121 ctccaagaag aatggatttt ccactggatt tgaccatagc gaccagattg gttttgagac
      181 cgatagcact catggccatg acaataagga atttagagag ttctttgaga ggggtaaaga
      241 aactactgga cacacctaga gaggtgagta gtgtagtgag gagagaggca aggataaagt
      301 aaaggataaa aagtgggaag acttttttca gttgtaggct ttgcttgttt tcttgttggc
      361 gactttgcca gtaggagaga aagagcgtga tagggataat agccaaagta cgtgtgagtt
      421 taacaatggt tgcagactcg agggtattgc tttggtaaag actgtcccaa gcgctggcgg
      481 cagccgttac agaggaagtg tcgttgaccg cagtccctgc aaagagggcg aagccttcat
      541 tggatagatg aagccaggtg ccgagggttg gaaagatgag cgcagccaag acattgaaga
      601 aaaagataac ggaaatggct tgggctactt ccttttcctt agcatcaata acgggcgctg
      661 tcgctgcaat ggcagaaccc ccacagatag aagaacctac tccaaccaag gtagccagtt
      721 ttgtatccag tgcaaagaaa cgctggaaga ggtaggcaat aatcagagct attgagatag
      781 tggacaggat gacagggagt gaagattggc caactgcgaa gacctgcgag atattgagac
      841 caaaaccaag caagacaacg gcatattgga gcaacttctt ggaactaaag gtcaaaccag
      901 catccagttg tttataggac gagagaaagg gatgtaggag catgcctatg aaaatggcaa
      961 aaacgggcgc gccaatcaca gggaagaatc ctcctaagta ccaagatacg atagaaatga
     1021 gaaggcaggc caagatacct gctccatttt ttgatagaaa tgacataaaa acctccaaat
     1081 aaaatctatt accattatag acctataaac aggaaaagta aaatagaaag tggaaagcta
     1141 ttctctaatg tatttttgcg gtcggggggc ttttgtagta taatagagat acgttttgaa
     1201 agtaggaggt atctatggac ttaactaagc gctttaataa acagttagat aaaattcaag
     1261 tttcgttgat tcgtcagttt gaccaggtta tttcggagat tcctggggtc ttgcgtttga
     1321 ccttggggga acctgatttt acaacgccag accatgtcaa ggaggcggcc aagcgagcga
     1381 ttgatcagaa ccaatcctac tatacaggga tgagtggtct gctgactcta cgtcaggcag
     1441 ccagtgactt tgttaaggaa aagtaccaac tggactatgc tcctgaaaat gaaattttgg
     1501 ttacaattgg ggcgacagag gctttatctg cgactttgac ggctattttg gaagagggag
     1561 acaaggtact tttgccagct cctgcttatc caggctatga accgattgtt aacttagttg
     1621 gggcagaaat tgttgagatt gatacgactg aaaatggttt tgtcttgact cctgagatgt
     1681 tggagaaggc cattttggag cagggtgata agctcaaggc ggttattctc aactatccag
     1741 ccaatccgac aggaattacc tacagtcgag agcagttaga ggccttggca gctgttttac
     1801 gcaagtacga aatttttgtt gtctgtgatg aggtttactc agaattgacc tacacaggcg
     1861 aagcccatgt gtctctagga acgatgttga gagaccaggc tattattatc aatggtttgt
     1921 ctaaatcgca tgccatgaca ggttggcgtt tggggctgat tttcgctcct gcggccttca
     1981 cagcccagtt aatcaagagt caccaatact tggtcactgc cgcaaatacc atggcgcaac
     2041 atgctgcggt agaagccttg acggctggta aaaatgatgc ggagcccatg aagaaggaat
     2101 atatccaacg tcgggactat atcatcgaaa aaatgactgc tcttggtttt gagattatca
     2161 aaccagacgg tgccttctat atttttgcta aaattccagc gggctacaat caagactcct
     2221 ttgcttttct gaaggatttt gctcagaaga aggccgttgc ctttatccct ggtgcagcct
     2281 ttggacgtta cggggaaggc tacgtccgcc tatcttatgc agccagcatg gagactatca
     2341 aagaagccat gaaacgactt gaggagtaca tgagagaagc atgattcagt ctatcacgag
     2401 tcaaggcttg gtgctttaca atcgcaattt tcgtgaggat gacaagctcg tcaaaatttt
     2461 tacagagcag gttggcaaac gcatgttttt tgtcaaacac gctggtcagt ctaagctggc
     2521 gcctgttatt cagcccttgg tgctggcacg atttctcttg cgaatcaatg atgacggact
     2581 cagttacatc gaagactatc atgaggtcat gacttttccc aagattaata gtgacctctt
     2641 tgtcatggcc tatgcgacct atgtggcagc tcttgcagat gctagtttgc aggacaatca
     2701 gcaggatgct cccttgtttg cttttttgca aaagactttg gagttgatgg aagcaggctt
     2761 ggattatcag gttttgacca atatttttga aattcaaatt ttgactcgat ttggaatcag
     2821 cctcaatttt aatgagtgtg tcttctgcca tcgggttggt caggcttttg acttttcttt
     2881 caaatatgga gcctgcctct gtccagagca ttatcatgag gataagagac gttgtcatct
     2941 caatcccaat atcccctatc tgctcaatca atttcaagct attgattttg agactttgga
     3001 gaccatttcg ctcaagcctg gaatcaagca agagctacgc caatttatgg atcaattata
     3061 tgaagagtac gttgggattc acctaaaatc aaagaaattt attgattccc tagcagactg
     3121 gggacaatta ctaaaagagg aaaagaaatg aaaaaaatcg cagtagatgc catggggggc
     3181 gattacgcac ctcaggccat tgttgagggt gtcaatcaag ccctatctga cttttcagat
     3241 atcgaggttc aactttacgg agatgaagct aaaatcaagc aatatctgac agcgacagag
     3301 cgcgtcagca ttatccatac ggatgagaag attgattcgg atgatgaacc tacgagagct
     3361 attaggaata agaaaaatgc cagtatggta ttggcagcca aggctgtcaa agatggtgaa
     3421 gcagacgctg tcctttcggc tgggaataca ggtgccttgt tggcagcagg attcttcatc
     3481 gtgggtcgta tcaagaatat cgaccgtcct ggactcatgt ctaccttgcc taccgttgat
     3541 ggaaaaggtt ttgacatgct agaccttggt gccaatgcag aaaatacagc ccagcacctc
     3601 catcaatatg cggttctagg ttccttctat gctaaaaatg tccgtggcat tgcgcaacca
     3661 cgcgttggtt tgctcaacaa cggaacagag agtagcaagg gcgacccgct tcgtaaggaa
     3721 acttatgaat tactggcggc tgatgaaagt ttgaacttta tcggaaacgt ggaagcgcgt
     3781 gatttgatga atggcgttgc agatgttgtt gtggcagatg gtttcacggg aaacgctgtg
     3841 ctcaaatcca tcgaagggac agctatggga atcatgggct tgctcaagac agctattaca
     3901 ggtggtggtc ttcgagcgaa actaggtgcc ctccttctca aggacagcct cagaggtttg
     3961 aaaaaacagc tcaattattc agatgttggt ggagcggtct tgtttggtgt taaggcacct
     4021 gttgtcaaga ctcatggctc aagcgatgcc aaggctgttt atagtacgat tcgtcagatc
     4081 cgtaccatgc tagaaacaga cgtggttgcc cagactgcgc gtgaattttc aggagaataa
     4141 aagagatgac agaaaaagaa atttttgacc gtattgtgac cattatccaa gagcgacagg
     4201 gagaggactt tgtcgtgaca gaatccttga gtctgaaaga cgatttggat gcggattctg
     4261 ttgacttgat ggagtttatc ttgactctgg aagatgaatt tagtatcgaa atcagcgatg
     4321 aggaaattga ccaactccaa agtgtaggag atgtggttaa aatcattcaa ggaaaatagc
     4381 aatcggagtt ccaagtcaac ggaagtagat ggtttttaga aatgagaaat atcggacaag
     4441 ctggtaaaat cttggctgac agtggttatc aagggctcat gaagatatat cctcaagcac
     4501 aaacttccac gtaaatccag caaactcaag ccgctaacag ttgaagataa agcctgtaat
     4561 catgcgctat ctaaggagag aagcaaggtt gagaatatct ttgccaaagt aaaaacgttt
     4621 aaaatgtttt caacaaccta tcgaaatcat cgtaaacgct tcggattacg aatgaatttg
     4681 attgctggta ttatcaatca tgaactagga ttctagtttt gcaggaagtc taatagtaaa
     4741 aaagtgatta gaaaacatct tttttaaaaa tagagatgat tttgaaacaa aaaagctaat
     4801 tcaagacgtt tcgatgccaa ttcaagattt ggatgaaaaa aattaataga tactgttata
     4861 ctaaacttgt caagtttgta acaagacaaa tattaaaaat aaaaaagagg tattcgttat
     4921 gaatacaaaa aagatgtcac aatttgaaat tatggatact gagatgcttg cttgcgttga
     4981 aggtggcgga tgcaattggg gagattttgc caaagcaggt gttggaggag gagcagtacg
     5041 aggtcttcag ctaggaatta aaacaagaac atggcaaggt gcagcaactg gtgctgcggg
     5101 aggagctata cttggaggtg tggcctatgc agcgacatgt tggtggtaat tatggatttt
     5161 aaaagtttta ttattggttt agtagttggt atatttggtc cttatatgga tgatttaatt
     5221 agaaaaaaat ttttaaagtc ttcggagaag aaaacagaaa aatctgttaa aaaataatca
     5281 aaactataaa tgatgaatct gaatcaaaat tattttgcgc atgtaaagag gagtcttata
     5341 gtaacgagtc aaaaaaggag taactatgaa tcgtaattta gaacggtgtt atctattctg
     5401 actaggaata gatcatacca gaggtagctt agaaatagca gggacattag aaattgaagt
     5461 aataaatagg atgtcgtaag tgttactatc aatgatttat ttgtttcaag cttgcctagg
     5521 gtgacagtaa aaaatcaatt tcctttcaat agcatatttt tagtgggcag gactcttgtt
     5581 ctgcctattt ttttatccaa aaagtgcagt tgggagggag ataggctcat ttgggaagga
     5641 agtccagttt ttgtttagtg attggggtaa gatagttgtt atcagatgag tttatactct
     5701 tcgaaaatca aattcaaacc acgtcaacgt cgccttgccg tatatatgtg actgacttcg
     5761 tcagtcctat ctacaacctc aaaacagtgt tttgagcagc ctgcggctag tttcctagtt
     5821 tgctctttga ttttcattga gtattaggga aaaggagatg aatatgaaat ttgggaaacg
     5881 tcactatcgt ccgcaagtgg atcagatgga ctgcggtgta gcttcattag ccatggtttt
     5941 tggctactat ggtagttatt attttttggc tcacttgcga gaattggcta agacgaccat
     6001 ggatgggacg acggctttgg gcttggtcaa ggtggcagag gagattggtt ttgagacgcg
     6061 agccattaag gcggatatga cgctttttga cttgccggat ttgacttttc cttttgttgc
     6121 ccatgtgctt aaggaaggga aattgctcca ctactatgtg gtgactgggc aggataagga
     6181 tagcattcat attgccgatc cagatcccgg ggtgaagttg actaaactgc cacgtgagcg
     6241 ttttgaggaa gaatggacag gagtgactct ttttatggca cctagtccag actataagcc
     6301 ttataaggaa caaaaaaatg gtctgctctc ttttatccct atattagtga agcagcgtgg
     6361 cttgattgcc aatatcgttt tggcaacact cttggtaacc gggattaaca ttgtgggttc
     6421 ttattatctg cagtctatca ttgataccta tgtgccagat cagatgcgtt cgacactagg
     6481 gattatttct attgggctag tcatcgtcta catcctccag caaatcttgt cttacgctca
     6541 ggagtatctc ttgcttgttt tggggcaacg cttgtcgatt gacgtgattt tgtcctatat
     6601 caagcatgtt tttcacctcc ctatgtcctt ctttgcgaca cgcaggacag gggagatcgt
     6661 gtctcgtttt acagatgcta acagtatcat cgatgcgctg gcttcgacca tcctttcgat
     6721 tttcctagat gtgtcaacgg ttgtcattat ttcccttgtt ctattttcac aaaataccaa
     6781 tctctttttc atgactttat tggcgcttcc tatctacaca gtgattatct ttgcctttat
     6841 gaagccgttt gaaaagatga atcgggatac catggaagcc aatgcggttc tgtcttcttc
     6901 tatcattgag gacatcaacg gtattgagac tatcaagtcc ttgaccagtg aaagtcagcg
     6961 ttaccaaaaa attgacaagg aatttgtgga ttatctgaag aaatccttta cctatagtcg
     7021 agcagagagt cagcaaaagg ctctgaaaaa ggttgcccat ctcttgctta atgtcggcat
     7081 tctctggatg ggggctgttc tggtcatgga tggcaagatg agtttggggc agttgattac
     7141 ctataatacc ttgctggttt actttaccaa tcctttggaa aatatcatca atctgcaaac
     7201 caagcttcag acagcgcagg ttgccaataa ccgtctaaat gaagtgtatc tagtagcttc
     7261 tgagtttgag gagaagaaaa cagttgagga tttgagcttg atgaagggag atatgacctt
     7321 caagcaggtt cattacaagt atggctatgg tcgagacgtc ttgtcggata tcaatttaac
     7381 cgttccccaa gggtctaagg tggcttttgt ggggatttca gggtcaggta agacgacttt
     7441 ggccaagatg atggttaatt tttacgaccc aagtcaaggg gagattagtc tgggtggtgt
     7501 caatctcaat cagattgata aaaaagccct gcgccagtac atcaactatc tgcctcaaca
     7561 gccctatgtc tttaacggaa cgattttgga gaatcttctt ttgggagcca aggaggggac
     7621 gacacaggaa gatatcttac gggcggtcga attggcagag attcgagagg atatcgagcg
     7681 catgccactg aattatcaga cagaattgac ttcggatggg gcagggattt caggtggtca
     7741 acgtcagaga atcgctttgg cgcgtgctct cttgacagat gcgccggtct tgattttgga
     7801 tgaggcgact agcagtttgg atattttgac agagaagcgg attgtcgata atctcatggc
     7861 tttggacaag accttgattt tcattgctca ccgcttgact attgctgagc ggacagagaa
     7921 ggtggttgtc ttggatcagg gcaagattgt cgaagaagga aagcatgctg atttgcttgc
     7981 acagggaggc ttttacgccc atttggtcaa tagctagaaa gaggagagga tgaaaccaga
     8041 atttttagaa agtgcggagt tttataatcg tcgttaccat aatttttcca gtagtgtgat
     8101 tgtacccatg gcccttctgc tcgtgttttt acttggcttt gcaactgttg cagagaagga
     8161 gatgagtttg tccactagag ctactgtcga acccagtcgt atccttgcaa atatccagtc
     8221 aactagcaac aatcgtattc ttgtcaatca tttggaagaa aataagctgg ttaagaaggg
     8281 ggatctcttg gttcaatacc aagaaggggc agagggtgtc caagcggagt cctatgccag
     8341 tcagttggac atgctaaagg atcaaaaaaa gcaattggag tatctgcaaa agagcctgca
     8401 agaaggggag aaccactttc cagaggagga taagtttggc taccaagcca cctttcgcga
     8461 ctacatcagt caagcaggca gtcttagggc tagtacatcg caacaaaatg agaccatcgc
     8521 gtcccagaat gcagcagcta gccaaaccca agccgaaatc ggcaacctca tcagtcaaac
     8581 agaggctaaa attcgcgatt accagacagc taagtcagct atggaaacag gtgcttcctt
     8641 ggccagtcag aatctagcct actctcttta ccagtcctac aagtctcagg gcgaggaaaa
     8701 tccccaaact aaggttcagg cagttgcaca ggttgaagca cagatttctc agttagaatc
     8761 tagtcttgct acttaccgtg tccagtatgc aggttcaggt acccagcaag cctatgcgtc
     8821 agggttaagc agtcaattgg aatcccttaa atcccaacat ttggcaaagg ttggtcagga
     8881 attgaccctt ctagcccaga aaatcttgga ggcagagtca ggtaagaagg tacagggaaa
     8941 tcttttagac aaggggaaaa ttacggcgag tgaggatggg gtgcttcatc ttaatcctga
     9001 gaccagtgat tctagcatgg ttgcagaagg tgccctacta gcccaacttt atccatcttt
     9061 ggaaagagaa gggaaagcca aactcacagc ctatctaagt tcaaaagatg tagcaagaat
     9121 caaggtcggt gattctgttc gctatactac gactcatgat gccgggaatc aacttttcct
     9181 agattctact attacaagta ttgatgcgac agctactaag actgagaaag ggaatttctt
     9241 taaaatcgag gcggagacta atctaacttc ggagcaggct gaaaaactta ggtacggggt
     9301 ggaaggccgc ttgcagatga ttacgggcaa gaaaagttat ctacgttatt atttggatca
     9361 atttttgaac aaagagtaat gttcgtgttt ttagagttaa ataattttta aactgtgaga
     9421 aagattcttc ttgcagtttt ttctttacaa tttttaaaaa aacatctgct atttattcgg
     9481 ttaaattctt gtgttttttg gttttttgtg gtaaaatgtg ctcaagtaat acgaaaggcg
     9541 aactttaaaa tgtcaaaaca attgatctat tcgggaaaag ctaaagatat ctatacaact
     9601 gaggatgaaa atcttattat ttcaacttac aaggaccagg cgactgcttt caacggtgtc
     9661 aagaaggagc agattgcagg taagggagtc ttgaataatc agatctcatc ttttattttt
     9721 gagaaattaa atgcggctgg tgtggcgact cactttgtgg agaaactttc agacacggaa
     9781 caactcaata aaaaggttaa gattattcct ttggaagtcg tgctccgcaa ctatactgct
     9841 ggttcctttt caaaacgttt tggtgtggat gagggaatcg ccttggagac tccgattgtc
     9901 gaattttact acaaaaatga tgatttggat gatccattta tcaatgatga gcatgtgaaa
     9961 ttcctacaga ttgcgggtga ccagcagatt gcctacttga aggaagaaac gcgtcgtatc
    10021 aatgaactat tgaaagtctg gtttgctgag attgggctta aattgattga ctttaagcta
    10081 gagttcggtt ttgacaagga tggcaagatt atcttggcag acgaattttc accagataac
    10141 tgccgcttgt gggacgctga tggcaaccac atggataagg atgttttccg tagaggattg
    10201 ggagaactaa ccgacgttta tgagattgtt tgggaaaagt tgcaggaatt gaaataatct
    10261 gtttgcaacg gaaaaccttc gtctctcaac taaaaggact caggctgaaa aggtccccca
    10321 gaccttttca ctctgtagag aactaggtga actaacagat gtttacgaaa ttgtctggga
    10381 aaagttgcag ggtttaaaat aacaacctca aggctgtttg ggaatattgc aagagctgaa
    10441 ataaaggaat aagaattgat ggataaacgt atttttgttg aaaaaaaggc tgattttcag
    10501 gtcaagtcag agagtttggt tagagagctc cagcacaact tgggactgtc aagcttgaaa
    10561 agtattcgta ttgtgcaagt atatgatgta tttgacttgg ctgaggactt gtttgcacct
    10621 gcagagaagc acattttctc tgagcaggga accgaccatg ttttagatga agtatctgtg
    10681 caggcggatc ttgctaacta tgctttcttt gccattgaaa gtctgccagg gcagtttgac
    10741 cagcgtgcag cttcgtcaca ggaagccttg cttttgttgg gaagttcgag tgacgtgaca
    10801 gtcaacacag cccaacttta cttggtgaat aaagatattg atgcgactga gttggaagct
    10861 gtcaaaaact acctgctcaa tccagttgat tctcgtttca aggatatcac gacagggatt
    10921 gccaagcagg agttttcaga gtcagacaag accattccaa aattgacttt ctttgaaagc
    10981 tatacagcag aagactttgc tcgctacaag gccgagcaag ggatggccat ggaagtggat
    11041 gatttgctct ttatccaaga ctactttaag tcaatcgggc gcgtgccaac tgagactgaa
    11101 ctcaaggttt tggacactta ctggtctgac cactgccgtc atacgacttt tgagacagag
    11161 ttgaaacaca tcgacttttc agcttctaaa tttcaaaagc aattgcagtc aacctatgac
    11221 aagtatattg ccatgcgcga ggagttaggt cggtctgaaa aaccacaaac cttgatggat
    11281 atggcgacta ttttcggtcg ttatgagcgt gctaacggac gattggatga tatggaagtc
    11341 tctgacgaaa tcaatgcctg ctcagttgaa attgaagtgg atgttgatgg tgtcaaggaa
    11401 ccttggctcc tcatgtttaa aaatgaaacc cacaaccatc caacagaaat tgagccattt
    11461 ggtggagcgg ctacctgtat cggtggagct attcgtgatc cgttgtcagg ccgttcctat
    11521 gtttaccaag ccatgcgtat ttcaggtgct ggtgatatta cagcaccgat ttcggaaact
    11581 cgtgctggga aattgccaca acaagtcatt tctaaaacag cagctcatgg ttattcttca
    11641 tatggtaacc agattgggct tgccacaacc tacgttcgtg aatacttcca cccaggcttt
    11701 gtagctaaac gtatggaact tggtgccgtt gttggtgcgg ctcccaaggg caatgttgtc
    11761 cgtgaaaaac ctgaagcagg tgatgtgatc atccttctcg gaggcaaaac aggtcgtgat
    11821 ggtgtcggtg gtgcgacggg ctcttctaag gttcaaacag ttgagtctgt agagactgct
    11881 ggtgctgagg ttcaaaaagg aaatgccatc gaagaacgca agattcagcg cctcttccgt
    11941 aatggcaatg tcactcgtct gatcaagaag tccaatgact ttggggcagg cggcgtctgt
    12001 gtggctatcg gtgaattggc agacggtctt gaaatcgacc tcaacaaggt gcctcttaaa
    12061 taccagggct tgaatggtac agaaattgcc atctctgaat cacaagaacg gatggcggtc
    12121 gtggttcgtc ctgaagatgt ggataccttc gttgccgaat gtaacaaaga aaatattgat
    12181 gctgttgtgg tggcgacagt aactgaaaaa ccaaatcttg tcatgcactg gaatggtgag
    12241 acaatcgttg acttggagcg tcgtttcctt gacaccaatg gtgtgcgcgt ggttgtcgat
    12301 gccaaagttg tggacaagga tgtcaaactc ccagaagagc gtcaaacatc tgctgaaaca
    12361 ctggaatcag atacccttac ggttctatct gacctcaacc atgcaagtca aaaaggatta
    12421 cagactatct ttgactgctc tgttggacgc tcaacggtta atcacccact tggtggtcgt
    12481 taccaactca caccaactga ggcatctgtg cagaaattgc cagttcaaca cggtgtgact
    12541 catactgcgt cggtcattgc tcaaggtttc aacccatatg tagctgaatg gtctccatac
    12601 cacggtgctg cttatgcggt tatcgaagca actgctcgtt tggtggctgc tggtgccaac
    12661 tggtctaagg ctcgtttctc ttaccaagaa tatttcgagc ggatggacaa gcaagcagag
    12721 cgtttcggtc agccagtagc tgctcttcta ggttctattg aagcacaaat tcagcttggc
    12781 ttgccatcta tcggtggtaa ggactccatg tctggtacct ttgaagaatt gaccgttccg
    12841 ccaaccttgg ttgcctttgg ggtgacgacg gcagatagcc gtaaggtgct ctctccagaa
    12901 tttaaagctg ttggggaaaa tatctactac atcccaggtc aagccctctc tgcagagatt
    12961 gattttgact tgattaagaa aaattttgct cagtttgaag caagccaagc tgaccataaa
    13021 gtgacgtctg catcagctgt caaatacggt ggtgtagttg aaagtttggc tcttgctacc
    13081 tttggaaact atattggtgc agaggtgacc ttgcctgaac ttaaaacagc tttgacagct
    13141 caattaggcg gctttgtctt cacatctcct gaagaaattg ctggagtaga gaagattgga
    13201 caaacgaaag cagactttac actgactgtc aacggtgtga agctagatgg acacaagctt
    13261 gacagtgcat ttcaagggac attggaagaa gtttacccaa cagaatttac ccaagcgaaa
    13321 gaactagaag aagtaccagc tgtggcatca gatgttgtga ttaaagccaa agaaaaggtt
    13381 gaaaaacctg tggtttacat cccagtcttt ccaggaacca actcagaata tgattcagct
    13441 aaggccttcg aaaaagaagg tgcagaggtc aatttggtgc cattcgtgac cttgaatgaa
    13501 gaagctattg tcaagtcagt tgaaactatg gttgacaata tcgacaagac taatattctc
    13561 ttctttgccg gtggattctc ggctgcggat gaaccagatg gttcagctaa gtttatcgtc
    13621 aatatcctgc ttaatgaaaa agtgcgtgtg gctattgata gctttatcgc ccgtggtggc
    13681 ttgattatcg gtatttgtaa tggattccaa gccttagtca aatcgggtct cctaccatac
    13741 ggaaactttg aagatgctaa cagtactagt ccaaccctct tctacaatga tgccaaccaa
    13801 cacgtgacca agatggtgga aactcgcatt gccaatacca actcaccatg gttggctggt
    13861 gtgcaagtgg gcgatatcca cgctattcct gtttcgcacg gtgaagggaa gtttgtcgtg
    13921 acggctgagg aatttgcaga gctccgtgac aatggacaaa ttttcagcca atacgttgac
    13981 tttaacggta aaccaagtat ggattctaag tacaatccga atggttctgt ccatgccatc
    14041 gaaggaatta ccagcaagaa tggtcaaatc atcggtaaga tgggccactc agaacgttat
    14101 gaggatggtc ttttccaaaa tatcccaggc aataaagacc aacacctgtt cgcatcagcg
    14161 gttaaacatt tcactggaaa ataagactta cagattttct aatagatagt atcagtaatg
    14221 taaaagtcat gtaaatctag ctcttgatga ttacaaatga aaattaggta taaaaaatga
    14281 catacgaagt aaaatctctt aatgaagaat gtggtgtttt cggtatttgg ggacatccag
    14341 atgctgctaa gttgacctat tttggactcc acagtcttca acaccgtggt caggaggggg
    14401 caggaatcct ctccaatgat caaggacaac tgaagcgcca tcgtgacatg gggcttttat
    14461 cagaagtttt cagaaatcca gccaatttgg ataaattgac aggagctggt gcgattgggc
    14521 atgtgcgtta tgcgactgct ggcgaagctt ctgttgataa catccagccc ttcctcttcc
    14581 gttttcacga tatgcagttt ggcttggctc ataatggaaa tctgaccaat gcagcctctc
    14641 tcaagaaaga actggaacaa agaggagcaa ttttcagcgc gacttcggac tctgaaatct
    14701 tggctcacct cattcgtcgt agtcataatc ctagcctgat gggcaaaatc aaggaagcgc
    14761 tcagccttgt caaaggtggt tttgcctata tcttgctgtt tgaggacaag ttgattgcgg
    14821 ctcttgaccc taatggcttt cgtccgcttt ctatcgggaa aatggccaac ggagcggtgg
    14881 ttgtttcctc tgaaacctgt gcttttgagg tcattggtgc cgagtggatt cgtgatttga
    14941 agccaggtga gattgtgatc attgatgacg agggcattca gtatgacagc tatacagatg
    15001 atactcagtt ggcgatttgt tctatggagt atatctactt tgctcgccct gattctaata
    15061 tccacggtgt caatgtccat acggcacgta agagaatggg agcgcaattg gcgcgagaat
    15121 ttaagcatga ggcagatatt gtagttggtg tgcccaattc ttccctaagc gcggctatgg
    15181 gatttgcgga agaatcaggc ttaccaaatg aaatgggtct gatcaaaaac caatacaccc
    15241 agcgaacttt tatccaaccg actcaagaat tgcgggagca aggagtgcgg atgaaactgt
    15301 ctgctgtttc gggtgttgtc aaaggcaaac gtgtggtcat ggtggatgat tccattgtac
    15361 gtggaacaac ctctcgtcgt atcgttcagc tcttgaaaga agcgggtgcg actgaggttc
    15421 acgttgccat tggaagtcct gcactagcgt atccatgttt ctacgggatt gatatccaga
    15481 cccgtcagga gctgattgca gccaatcata cggtcgaaga aactcgccaa atcattggtg
    15541 cggacagtct gacttatctt tcaattgatg gcttgattga gtcgattggt atcgaaacag
    15601 atgcgccgaa cggtggtctc tgtgtcgctt actttgacgg tgactaccca acgcctctct
    15661 atgactacga agaagactat cgtagaagtt tggaagaaaa gaccagtttt tacaagtagg
    15721 cgacagattc tccattaaag aaaaggaaaa aacaaatgac aaataaaaat gcatatgccc
    15781 agtcgggtgt ggatgttgaa gcgggttatg aagttgttga acggattaaa aagcacgtgg
    15841 cccgtacgga gcgtgcaggt gtcatgggag ctcttggtgg ctttggtggt atgtttgacc
    15901 tttccaagac tggggttaaa gaacccgtct tgatttcagg gactgacggt gtcggaacca
    15961 agctcatgtt ggctatcaag tacgacaagc acgataccat cgggcaggac tgtgtggcca
    16021 tgtgtgtcaa cgacatcatt gctgcaggtg cggaacccct ctattttctc gactacgtag
    16081 cgacagggaa gaatgaacca gctaagctag aacaagtggt tgctggtgtg gcagaaggtt
    16141 gtgtgcaggc tggtgctgcc ctcatcggtg gggaaacggc tgaaatgccg ggcatgtacg
    16201 gcgaagacga ctatgacttg gctggttttg cggtcggtgt ggctgaaaaa tctcaaatca
    16261 ttgacggttc aaaggtggta gagggagatg ttcttctcgg acttgcttca agtgggattc
    16321 actcaaatgg ttactctttg gttcgtcgtg tctttgcgga ttacacaggt gaggaagtcc
    16381 taccagaatt ggaaggcaag aaacttaagg aagttctact tgagccgact cgtatctatg
    16441 tcaaggctgt cttgccgctc atcaaagaag agttggtcaa cggcattgcc cacatcacag
    16501 gtggtggctt tatcgaaaat gtccctcgta tgtttgcaga tgacctagct gctgaaattg
    16561 atgaaagcaa agttccagtg cttccaattt tcaaagccct tgaaaaatat ggtcagatta
    16621 aacacgaaga aatgtttgaa atcttcaata tgggtgtggg acttatgttg gcggtcagcc
    16681 ctgaaaatgt agagcgtgta aaagaattgt tggatgaagc agtctatgaa attggtcgca
    16741 tcgtcaagaa agaaaacgaa agtgtcatta tcaaatgaaa aaaatagcgg tttttgcctc
    16801 tggtaatggc tcaaattttc aggtgattgc cgaagaattt ccagtggagt ttgtcttttc
    16861 agaccatcgt gatgcctatg tgcttgagcg tgcaaagcag ctcggcgttc tgtcctatgc
    16921 ttttgaactc aaggagtttg agagcaaggc agactacgaa gcagcccttg tcgaactctt
    16981 ggaagaacac cagattgcct tggtttgcct agcaggctac atgaaaatcg ttggaccaac
    17041 cttattgtcg gcttatgaag gtcggattgt caacattcat ccagcctact tgccagaatt
    17101 tccaggagct catgggattg aggatgcttg gaatgctggc gtgggtcagt ctggtgtgac
    17161 cattcactgg gtggattcgg gtgtggatac aggccaggtc atcaaacagg ttcgtgtgcc
    17221 acgactagct gatgatacca ttgacagatt tgaagctcgc atccatgaag cagagtacag
    17281 gttgtatccg gaagtagtga aggctctatt tacagattga ctttttgatg attcatatga
    17341 tatctttgat tttaaattgg agtcagtgtt tgttgaagac ggcttcaaac ggaggtattt
    17401 gtaatgttag aatctaaaaa aacaactcga tatgtatttt atgtctatct gatgttatta
    17461 acttggggaa tcttatttaa gtttgaaaca aatcctgaat ttatagcatt tttcttagct
    17521 ccaaggtata tcaattggat tccattttca gaaccactaa tagtcgatgg aaaaattgtt
    17581 tttgctgaaa tgttatttaa tctgattttc tttattccat taggtgtttg tttccctttg
    17641 ataaaaacta atttatctag tttaagaata gtcgggacag gtttcttgat tagtttattg
    17701 tttgagtgct tacagtatat tttagcaata ggtataacag atataacgga tttgacttta
    17761 aatacgctag gtgtctgtgt aggcttactg atttatcaaa tttttataag agtgttcaaa
    17821 tcacagacta gaaaatggat caatatctta ggtatgctta gccttggttt tgcttatctt
    17881 gttttactgt tactgcattt aattggtgtt taactaatga ttaaaaagga gaatataatg
    17941 actaaacgcg tcttaatcag cgtctcagac aaagcggaca ttgttgaatt tgcccaagaa
    18001 ctcaaaaaac ttggttggga gattatctcg acaggtggaa ctaaggttgc ccttgataat
    18061 gctggggtgg ataccattgc tatcgatgat gtgactggtt tcccagaaat gatggacggt
    18121 cgtgtgaaga ccctccaccc aaatatccac ggagggcttc tcgctcgtcg tgacttggat
    18181 agccacttgg aagcggctaa ggacaacaag attgagctca ttgaccttgt ggtggtcaac
    18241 ctttacccat ttaaggaaac tatccttaaa ccagatgtga cttatgatga tgcagttgaa
    18301 aatatcgata ttggtgggcc atctatgctt cgttcagcag cgaaaaatca tgccagtgtt
    18361 acagttgtgg tagatcctgc tgactacgct gtggttttgg acgaattggc agcaaacggc
    18421 gaaacctctt atgaaactcg ccaacgttta gcagccaaag tatttcgtca cacagcggct
    18481 tatgacgcct tgattgcaga atacttcaca gctcaagtgg gtgaaaacaa gcctgaaaaa
    18541 ctcactttga cttatgacct caagcaacca atgcgttacg gtgagaatcc tcaacaagac
    18601 gcggactttt accagaaagc tttgcctaca gactactcca ttgcttcagc caaacagctc
    18661 aacgggaaag aattgtcatt taataatatc cgtgatgcag atgctgctat ccgtatcatc
    18721 cgtgacttca aagatagtcc aaccgttgtg gctctcaaac acatgaatcc atgtggaatt
    18781 ggtcaagctg atgacatcga gactgcttgg gactacgctt atgagtctga cccagtgtct
    18841 atctttggtg ggattgtcgt cctcaaccgt gaggtggatg ctgcgacagc tgagaagatg
    18901 cacggcgttt tcctcgaaat catcattgca ccaagctata cggatgaagc gctagccatt
    18961 ttgatcaata aaaagaaaaa cttgcgtatc cttgccttgc catttaatgc tcaagaggct
    19021 agcgaagtgg aagcagaata cacaggtgta gtcggtggac ttctcgtgca aaatcaagac
    19081 gtggtcaagg aaagcccagc tgactggcaa gtggtgacta aacgtcagcc aactgagaca
    19141 gaagcgactg ctcttgagtt cgcttggaag gctatcaagt acgtcaaatc aaatggtatt
    19201 atcgtgacca acgaccacat gacacttggt gttggtccag gtcaaaccaa ccgtgtggct
    19261 tctgttcgcc ttgccattga ccaagccaaa gatcgtctgg acggggcggt ccttgcttca
    19321 gatgccttct tcccatttgc ggataacgtg gaagaaatcg ccaaagcagg aattaaggcc
    19381 atcatccagc ctggtggctc tgtccgtgac caagaatcca tcgaagcagc ggataaatac
    19441 ggcttgacta tggtctttac aggtgtgaga cattttagac attaagaaga taaaagggaa
    19501 gaaaacagtt tctttccttt tttggcttaa aatgctaact gaaacaagat taaaacgaac
    19561 ttttttgata taatgttggt aaataattcg caaaagaggt tgaggaatga aactgcttgt
    19621 tgtcggttct ggtggtcgtg agcatgcgat tgctaaaaag ttacttgaat caaaagacgt
    19681 ggaaaaagtc tttgtagctc ctgggaatga tgggatgact ctggatggtt tggaattggt
    19741 aaatatctct atttccgaac attctaaatt gattgacttc gcaaagacca atgatgttgc
    19801 ttggaccttt atcggtccag atgatgccct tgctgctggt atcgtggatg attttaacca
    19861 agctgggctt aaggcctttg gtccgactag ggctgcagcg gagctggagt ggtccaagga
    19921 ttttgccaag gaaatcatgg tcaaatatgg tgtttcgaca gcagcctatg gcacattttc
    19981 agatttcgag gaagcaaagg cctatatcga aaagcatggt gcgcctatcg tagtcaaggc
    20041 ggatggcttg gcgcttggga agggtgtcgt cgtttctgag acggttgagc aagcggtcga
    20101 agccgctcat gagatgcttt tggacaataa atttggtgac tcaggtgcgc gcgtggttat
    20161 tgaggaattc tttgaaggag aggaattttc actctttgcc tttgtcaatg gtgataagtt
    20221 ctacatcatg ccaacggctc aggaccacaa acgtgcctat gatggcgaca aagggcctaa
    20281 cacgggtggt atgggtgcct atgcgccagt tccacactta ccacagagtg tagttgatac
    20341 agcggttgac accattgtca agccagttct agaagggatg attaaagaag gtcgccctta
    20401 tctgggagtt ctttacgcag ggcttatcct gacagctgat ggaccgaaag tcattgagtt
    20461 caacgctcgg ttcggagatc cagaaactca gattatcttg cctcgcttaa cctctgactt
    20521 tgctcaaaat atcacagata tcctggatag caaggagcca aatatcacgt ggacggacaa
    20581 gggtgtgact ctgggtgtgg ttgtcgcatc caagggctac ccgctaaatt attcaaaggg
    20641 tgttgagttg ccagtcaaaa ccgatggcga catcattacc tactatgcag gggctaagtt
    20701 tgcggaaaat agcagagcac tgctctcaaa cggcggacga gtttatatgc tcgttaccac
    20761 agcagatacc gtcaaagaag cccaagccag catctaccaa gaactatccc aacaaaaaat
    20821 agaaggactc ttctaccgaa cagatatcgg aagcaaggca attaagtaaa gatataagaa
    20881 taacgcgccg tagtcgccaa acacgataat ggtcgtcgtg gtgaaaagac cagaacagtg
    20941 aatgttctgg tcagggggaa acttggagac cgtaggctca aagtttagga atgaaaccga
    21001 aggtttgctt ccgcctccat cacctaagac cattatcaaa aagaaaaata aaaattcaca
    21061 aaatacgtta atgatcgtat ggtttgcgag cgttagcgag ctaatataga acaatcaccg
    21121 ccgttgtgaa agaacgattg gatgataatc caatcgttca gggaaattgg aagaccttgg
    21181 gtttccaatt taggcatgag acacctttgg tggctgctgc cgtccctcac aagctaaggt
    21241 gattgttgaa aaagaggaaa aaggagaaga aatgaaacca gtaatttcca tcatcatggg
    21301 ctcaaaatcc gactgggcaa ccatgcaaaa aacagcagaa gtcctagacc gcttcggtgt
    21361 agcctacgaa aagaaagttg tttccgcaca ccgcacacca gacctcatgt tcaaacatgc
    21421 agaagaagcc cgtagtcgtg gcatcaagat catcatcgca ggtgctggtg gcgcagcgca
    21481 tttgccaggc atggtagctg ccaaaacaac ccttccagtc attggtgtgc cagtcaagtc
    21541 tcgtgctctt agtggagtgg attcactcta ttctatcgtt cagatgccgg gtggggtgcc
    21601 tgttgcgacc atggctatcg gtgaagctgg agcgactaac gcagctctct ttgccctccg
    21661 tctcctctct gtagaagata agtccattgc ggatgcactt gccaactttg ctgaagaaca
    21721 aggaaaaatc gcagaggagt cgtcaaatga gctcatctaa aacaatcgga attatcggtg
    21781 gcggtcaact gggtcagatg atggccattt ctgctatcta catgggccac aaggttatcg
    21841 cgctggatcc tgcggcggat tgcccggcct ctcgcgtggc ggaaatcatt gtggcacctt
    21901 ataacgatgt ggacgccctc cgtcagttgg cagaccgttg cgatgtcctc acttatgagt
    21961 ttgaaaatgt cgacgctgac ggtttggatg ccgttatcaa ggatggacaa ctccctcaag
    22021 gaacagatct gctccgcatt tcgcaaaatc gtatttttga aaaggacttt ttgtcaaaca
    22081 aggctcaagt cactgtggca ccctacaagg tcgtgacttc tagcctagac ttggcagata
    22141 tcgacttgtc gaaaaactat gtcctcaaga ctgcgactgg tggctacgat ggtcatggac
    22201 aaaaggttat tcgttcagaa gcagacttgg aagcagccta tgcgctagca gactcagcag
    22261 actgcgtctt ggaagaattt gtcaactttg accttgagat ttctgtcatc gtgtcaggaa
    22321 atggcaagga ggtgacgttt ttcccagttc aggaaaatat ccaccgcaac aatatcctgt
    22381 ctaagaccat cgtaccagcc cgcatttctg aaagtctagc agacaaggct aaagctatgg
    22441 cagtgcgaat cgcagaacaa ctcaacttgt ctggaactct ctgtgtggaa atgtttgcga
    22501 ctgatgatga cgttattgtc aatgaaatcg ccccacgacc acataactct gggcactatt
    22561 ctattgaagc ctgtgatttc tctcagtttg acacccatat tctgggtgtt ctcggagcac
    22621 cattaccagt catcaaactc catgcgccag ccgttatgct taatgtcctc ggtcagcatg
    22681 tcgaggctgc tgagcaatat gtgacagaaa attcaagcgc ccacctccac atgtatggta
    22741 aaatagaagc gaagcacaac cgcaagatgg gacatgtgac cttgtttagt gatgtaccgg
    22801 atagtgtgga tgagcttggg gaagggattg atttttagga caagtctatg atacaaatta
    22861 tcgttaatac atttattgaa aaggataaga ctggagcagt tgttgaagtg ttgtatgcca
    22921 gtgctgacca agataaggta caagctaaat atgaagaact agctgcacaa taccccgaaa
    22981 attatttagc tatctatgat gtaccgctgg atacggattt gaatacacta gatcattacc
    23041 cgtctgtgtt tattgaaaaa gaggagtttg agtagaaatc ttggtttacc tagatagctt
    23101 attcccaaca gcttaagaag aaaggaaaaa ttaacacatg atcaaccgtt actctcgccc
    23161 tgagatggcg aatatttgga gtgaagaaaa taaataccgt gcttggcttg aggtggaaat
    23221 cctctctgac gaggcatggg ctgagttggg ggaaatccct aaggaagatg tggctttgat
    23281 tcgcaagaag gcggactttg acatcgaccg tattttggaa attgagcagg agacgcgcca
    23341 cgatgtggtg gctttcacgc gtgcggtttc tgagactctt ggtgaagagc gcaagtgggt
    23401 tcactatggg ttaacttcta ccgacgtggt ggatactgct tatggttacc tctacaagca
    23461 ggccaacgac atcatccgtc gtgaccttga aaacttcact aatatcatcg ctgacaaggc
    23521 caaggagcac aagttcacca tcatgatggg gcgtactcat ggtgtgcacg ctgagccgac
    23581 aacctttggt cttaaattgg caacttggta cagcgaaatg aaacgcaata tcgagcgttt
    23641 cgagcatgca gctgctggtg tagaagctgg taagatttct ggtgcggttg ggaactttgc
    23701 caatatccca ccatttgtag aggagtatgt ctgcgataaa cttggcatcc gtgcccaaga
    23761 aatctctaca caagtccttc ctcgtgacct tcacgctgag tactttgcgg ttcttgccag
    23821 cattgcgact tcaatcgaac gtatggcgac tgagattcgt ggtctacaaa aatctgagca
    23881 acgcgaagta gaagagttct ttgctaaagg gcaaaaaggg tcttcagcaa tgcctcacaa
    23941 acgcaaccca atcggttctg aaaatatgac tggtctggcg cgtgtcattc gtggtcacat
    24001 gattacggct tatgaaaacg tcgctctctg gcacgaacgc gatatttctc actcatcagc
    24061 tgagcgtatc atcacaccag atacgaccat tttgattgac tacatgctca accgttttgg
    24121 aaatatcgtc aagaacttga cagtcttccc agaaaatatg atccgaaaca tgaactcgac
    24181 ttttggtctt atctttagcc aacgggctat gttgacattg attgaaaaag gcatgacccg
    24241 tgagcaagcc tatgacttgg tgcaaccaaa aacagcctac tcttgggaca accaagtaga
    24301 ctttaaacca cttcttgagg cagattcaga agtaacatca cgtctcactc aagaagaaat
    24361 cgatgaaatc ttcaacccag tttattacac caaacgagtg gatgatatct ttgaacgtct
    24421 tggactaggt gattaattaa aaaataaaca gcgagcttca atctcgctgt ttatttttta
    24481 tcgaaaagac ttagtcttct tttcttttag tgagtccata ggctgctagt gtggccatga
    24541 gtcctgcgac tactagtcct gcagaatcgt gagttcctgt ttcaggaagt tttttctcta
    24601 ttaccacagg agctggatct tgaggaagag ctttgctttc ctcagcagga gcagttgatg
    24661 gagctggttg gcttgggatt tctagttttg gtttttcttc agcaatagcg gcttgtccgt
    24721 tttcatcgcc tacatgtgtt accatagttc cgacttcgac tatttgagta acggcttcct
    24781 gtgctacgac actatttaca agtgttttca cttccttacc atcggcagaa gtgctcacag
    24841 agtagaagtt gctacgatgt ccattgacgc ccttagtaat gacttgtgtt tttcctttga
    24901 gtaagagtgg attttcacga gtcactgtgg taaatggaat ttcttctttt tggatatcca
    24961 gtctaggttt tacctcagta gttggtgcaa gaccactttc atcacccttg tgagttacag
    25021 gagcgccaac ttcaaccact tggtttataa cttctttggt tacctggcta tcaaggactg
    25081 tttctgttgt ttttccattt tcagtgagta cagagatgta atgagttcgc tcacctttga
    25141 ctcctgctgt gataatattt tcctgaccag ctgggaggtt aggattttct ttcttgataa
    25201 cttcaaatgg aatttcttca gttcttgtga tgagttctgg tctggtttca acattggcag
    25261 ccacttcatt ttcatccagg cttcctgaat gagttgcagc tggtttgagg ccttgaagag
    25321 cggcttttag gttggctaca agtgtgtcaa gctcagcttg tttattacgg ttgaggttgt
    25381 aatttagagc tgttttagct gcgtcaaggg cctcaagact ttctttacta tatccttcta
    25441 agtttgtagg aattttagct aattcttcgc ggagagcatt ataattagca cggaagtagt
    25501 ctttgttgtg gtctgcaaag gcagtcatga gttcaaagat ttcctcttcc ttgtattcag
    25561 cgcttggtct atctgcccag attgaaagca tacttccgac tgttggaaga tctacttcag
    25621 gatatttggt agaagctagt tgattgaatg gtgtttttcc agtattctca atagctttct
    25681 tgaggaaacc accaccatct tctggttttt gaccaagaat gtagtaccag tcaccgttgg
    25741 tattcaagaa tttatagcct ttgcttgcta ggtattgagg tgatgcgagg ttatatcccc
    25801 accagccttt agaccagtaa gaaatcaaga catctttgtc aaactgaaca tcgtccttgt
    25861 cttcatagta gaagccatcg ttgaaggcca ttggttgaag ccctctttct ttggccatag
    25921 ctgcgagggt gttggcatat tcggcaaatt tgccatagag ttgataccac ttgaggtagt
    25981 accagccttg ggcactagtc gcatcgttgg cgtattcgtc agtaccaaag ttgaaaatct
    26041 ttgttttacc tgcaaagaag tccatgtatt taccgatgag ggcttttaca aagttcatcg
    26101 cttcttcgtt tttcaagtcc atagttgttt ttgaaacttt atcaaagtgg gcttgaggat
    26161 ttttaatacc taatttttcc atggcaacca gcatagcatc catgtgacct ggactgttaa
    26221 tagctgggat gagaccgatg tccttagatt tagcgtattc aattagctct gttacttctg
    26281 cctgtgttag tgcagtaccg tttggatcgt cgtagtaagc tttagttcct tcgataatag
    26341 cttttttaac gtcatcacta gcataggttt ttccgttggc agtaatggtc atatcatcga
    26401 gtagaaagcg aagtccgtca tttcctagaa ggagatggac atcagaatat ccgagctcac
    26461 tggccttgtc tacgatgcgt ttgagctggt tcagagtaaa gtatttgcgt ccagcatcga
    26521 ttgagattac cttgtttttg gcaagttttt caacctcacg tttagcttct tcttcttttt
    26581 gagcttcagg cgtgagggtc aagttgttga cagtttcttg aagtttagca atggcttgat
    26641 caatcgtatc ttgttgggca cggctaaggt tgctatcgag agagcgaata gctttttcag
    26701 cttcttttac ggccgcgacg ctttctgcag tataacggtt caggtctttt ggtacctcgt
    26761 taagtgtttg ctctgcagat tcataatcag ctgcgaagta ttcagcgttg gcatttgcaa
    26821 aatgacgcat gagtttgaag aggcgtgatg gtgaataacg tgcagatgga gtgtcagccc
    26881 aagcagctac catactaccg atgattggga tatcagctcc ttctgttttt ggtacagaag
    26941 tgattggtgt gtttttaata ccattgagcc cctgatcgag attgtaccag ccttggccat
    27001 cagcgtttcg tccaagaacg tagtaccaag catcattggt attaaggatt tggtgacctt
    27061 tttcagctag tagtttagaa gaagcgacat cgtagcctcc ccaaccacca gtccacatag
    27121 aaacgatgat gtctttgtca aaactaccaa agcttgtgtc gctattgtag tagataccgt
    27181 cgttaaaggc cattggtttg agaccgtgcg attttacaat acgagcgagg tcattggcgt
    27241 aggcaataaa tttttcatag ccttttacag ggtagccttc gtttggatag tatttatcag
    27301 cttgaagcac actccaacct ttagcatctg tcgcatcatt ggcatattca tcaagtccga
    27361 tgttgaagat ttcagtcttt ttcgcgaaat aagcagcata cttgtcgata agggcttttg
    27421 taaaagcgac agcttgttcg ttgtcaagat tgacagtacg ggctgattcc ttcccaaaat
    27481 agctaaagtt agggttttgg attcccaatt ctttcatggc attgagaatc gcatccatgt
    27541 gaccaggact atttactgtc ggaatgagac cgataccttt atctttggca tagttaatca
    27601 gatctgtcat ttgactttct gttaagtgat tgccgtttgg atcgttgtaa taatcatttg
    27661 tacctttttc aatggcgcgt ttgacatcgt cactggcata ggtcttgccg ttagctgtga
    27721 tgctcatatc gtccaacatg aaacggagtc catcatttcc gactaatagg tgtaaatcag
    27781 tgtagccata atgtttcgct ttatcgatga tttccttgag ctgttctggt gagaaatatt
    27841 tacgtccagc atcaatagaa acaattttct ttttcgctag tttttcattt acagttgcag
    27901 cacgttcctt tcctgcctct gtttccggtt tgtcatcctc tgctttcgct tcatcttttt
    27961 tagctggttt atccttgtca gtcttgtctg tatttgactc tttagaatca acctctttcg
    28021 cttcttcctt tttagggcta gcttcttctg cctttttatt agcagtttct ttttcagcag
    28081 aagttggagt taccacttct gctttatcac taggagttga actaacttcc tcttgtggtt
    28141 tttcttctgt ttttggaaga ctagctacct tatcagtagc tggagtttct gtttctacag
    28201 tttttggagc ttctggttga agctctgctt taggtgtttc ctcagtccga ttttcggatg
    28261 attgagggga atcagaaacc gtatggatgg tcggttggtt ttctgtagta gtaggagtaa
    28321 ctccatcggc tgcaacagtc tgtgcttgga aggcaaatcc aattagaaca gaagctgctc
    28381 ctacagcgta tttacgaata gaaaaacgct gttgtttttc atgtttcatt gcaaaacctc
    28441 ctgattgcat tgttatattg atagcgatta tataaatcaa cgcctttatt ttatttctta
    28501 tattaacgag agtcaagagg agatgacaaa aaactataat aagtataaaa aaatataaaa
    28561 tttaaactta agatttcaga ttggtcggaa aaaatacgta tatatatcta gtataatttt
    28621 tggttctatt tctataaaat attccacaaa ttatagaatt ttccaaaaat aggtaagcgc
    28681 tacctttttg gtgtggtata ataagcatag aaaaagccca agcgattagc tcaggctttc
    28741 ttcttagtga tcacggtcac atgagataaa tttaatcttg tagtaatcag atcgtttgta
    28801 agtttcactg tattctaaaa cttggccagt tgattcgagt ttggtgattt tagtttgtag
    28861 gacagtaggg aattgttcat cgactccgag gactgaagcc gcatgttctg gagttggaaa
    28921 gactatttcg ttgatttctt caaagtgttc atcattcatg tgaatgtggt agtctaactt
    28981 gaaacgatta tagatagaac tatagtattc aaggtttgga taatttgcgt tgatatattg
    29041 ttctgggatg taggatgtat ggtagatata aacgacaccg tttgattcgc ggatacgttc
    29101 aatcttgtag tagaattgat cgccgcgtag acccaatttt tccaagtaaa caagcttgtt
    29161 tccgcgttca attgaaagaa cagttacctt atcatcttta gcattgaaga gttcaatatc
    29221 tgaaaactct acaagcttgt gtttgcgtgc acgtgaaacg aaggttcctt ttccttgttg
    29281 gcggacaata tagccatctt tggcaaggtc gtttaaggcg cgaacaactg tgatagagct
    29341 gacatcgtac attgaaatga gttctgcttc agtgtaaaat ttatctccac tgctaaactg
    29401 cccagagatg attttatttt ttaattcgtc ttttatgtat tgatatttgg gaattgccat
    29461 atttttacct ctattttcct tctccatagg aaattttacc ataaaagcga aaaaaatagt
    29521 agtcttttga ataaaaaatt agaataatag tttgaaaaat taagcgatat agggattgct
    29581 catattttat caatgtattc tatacaaaat tattttaggt cccatattcc gaatttaaag
    29641 agcgtttgaa atgggtctaa aaatgtttga aactaattga atgtgtgtat aatagtaaaa
    29701 atgcagtaaa tatcccgaca atttctattg acaattcaaa cagattggtt tataattaat
    29761 ataacaacaa atgaaagcgc aaactttcgc ggtcggaagg tagttttatg acacgatttg
    29821 agatacgaga tgatttctat ctcgatggaa aatcatttaa gattttatct ggtgccattc
    29881 attattttag ggttcctcca gaggattggt atcattcgct ctataacttg aaggctcttg
    29941 gttttaatac ggtagagact tatgttgctt ggaatttaca cgagcctcgt gaaggtgagt
    30001 ttcattttga aggtgatctg gatttagaga aatttctcca aatagcgcag gatttgggtc
    30061 tctacgcaat tgtgcgtccg tctccattta tctgtgcgga atgggaattc ggtggcttac
    30121 cagcttggct cttgaccaag aacatgcgaa ttcgctcatc cgacccagta tatatcgagg
    30181 cagttggtcg ctactatgat cagttattgc caagactggt gcctcgtttg ttggacaatg
    30241 gtggcaatat tctcatgatg caggttgaaa atgagtatgg ttcttacgga gaagataagg
    30301 cttacctgag agcgattcga cagctaatgg aagagtgtgg cgtaacctgt cccctcttta
    30361 catcagatgg tccatggcga gctactctga aagctggaac cttaattgaa gaggacctct
    30421 ttgtaacagg aaactttggt tctaaggcac cttacaactt ttcgcagatg caggaattct
    30481 ttgatgaaca tggtaagaaa tggccactca tgtgtatgga gttctgggat ggttggttca
    30541 atcgctggaa agaaccgatt atcacacggg atcctaagga attggcagat gcagttcgag
    30601 aggttttgga acaaggctct atcaatcttt acatgttcca cggtggtaca aactttggtt
    30661 tcatgaatgg ttgctcagct cgaggaactt tggacctgcc acaagttacg tcttatgatt
    30721 acgatgccct tctggatgaa gaaggaaatc caactgctaa atatcttgca gtcaagaaga
    30781 tgatggcaac acatttttca gagtatccgc agttggaacc actctacaaa gagagtatgg
    30841 agttggatgc tattccacta gttgaaaaag tttctttgtt tgaaacctta gatagcttgt
    30901 caagtcctgt agaaagtctc tatcctcaaa agatggagga gctgggacaa agttatggct
    30961 acctacttta tcgaacagaa acaaactggg atgcagaaga agaaagactt cgtatcattg
    31021 atggtcgaga tagggcccag ctgtatgtcg atggtcagtg ggttaaaact caatatcaga
    31081 cagagattgg ggaagatatt ttttatcaag gtaaaaagaa agggctatct aggttagata
    31141 tcttgataga aaatatgggg cgtgtcaact atgggcataa gttcttagcg gatacgcaac
    31201 gtaagggaat tcggacaggg gtctgtaagg atctgcattt cttactaaac tggaaacact
    31261 atccactccc actagacaat cctgagaaaa ttgatttttc aaaaggatgg actcaaggac
    31321 aaccagcctt ttacgcttat gactttacag tcgaagagcc aaaagatact tacctagact
    31381 tgtctgagtt tggtaagggg gttgcctttg tcaatgggca gaatctagga cgtttttgga
    31441 acgttggccc aactctctca ctttatatcc ctcatagcta tctcaaggaa ggtgccaacc
    31501 gcatcattat ctttgaaaca gaaggtcaat ataaagaaga gattcattta actcgtaaac
    31561 ctacactaaa acatataaag ggggaaaact tatgacaatt gtaggatgcc gtattgatgg
    31621 acgtttgatc cacggacaag tagccaatct ttgggctgga aaactaaatg tttcacgcat
    31681 tatggttgta gacgacgaag ttgtcaacaa cgatattgaa aagagtggtt tgaaacttgc
    31741 gacaccacca ggtgtgaaat tgagtatttt gccagttgag aaagctgcag ccaatattct
    31801 tgctggtaaa tacgatagcc aacgtctctt tatcgtggct cgtaaaccag accgcttcct
    31861 tggtttggta gaagcaggtg taccacttga aacccttaat gttgggaata tgtctcaaac
    31921 accagaaaca cgttctatta cacgttctat caacgtagta gacaaggatg tggaagactt
    31981 ccacaaactg gcagaaaaag gtgttaaact tactgctcag atggttccaa atgatccaat
    32041 ttcagacttt ttgagcttat taaaatagga aaaaaatttt taggaggtca ttgttatgat
    32101 acaatggtgg caaattttac ttctcacttt gtactcagct tatcaaatct gtgatgagtt
    32161 gacgatcgtt tcatctgcag gttctcctgt atttgctggt ttcattactg gtttaatcat
    32221 gggagatgtg actactggtt tacttatcgg tggtaacttg caactgttcg ttcttggggt
    32281 tggtaccttc ggtggtgctt ctcgtatcga cgcaacttct ggtgcggttc ttgcgacagc
    32341 cttctctgtt tcacaaggaa ttgatgcacc gcttgccatt actacaatcg ctgtaccagt
    32401 agcagctctc ttgacttact tcgacgttct tggtcgtatg actactacct tcttcgctca
    32461 ccgtgtggat gctgcaatcg aacgctttga ctataaaggt attgaacgca actacttgct
    32521 tggtgcgatt ccgtgggctc tatctcgtgc ccttccagtc ttctttgccc ttgcttttgg
    32581 tggtgccttt gtacaatcag tagtagactt cgttgaagcc tacaaatggg ttgcagatgg
    32641 cttgacactc gcaggacgta tgcttccagg tcttggattt gcaatcttgc ttcgttacct
    32701 tccagttaaa cgtaaccttc actaccttgc tatgggattt ggtttgacag ctatgttgac
    32761 tgttctttac tcatatgtaa caggtcttgg tggcgctgtt gctggtatcg taggtactct
    32821 tcctgctgaa gttgctgaaa aaattggttt cgtgaacaac ttcaaaggtt tgtctatgat
    32881 tggtatttct atcgtaggta ttttccttgc agtgcttcac ttcaaaaata gccaaaaagt
    32941 agctgtagca gcaccttcta caccatcaga aagtggggaa atcgaagatg acgaattcta
    33001 attacaaact tacaaaagaa gattttaatc aaatcaacaa acgtagcttg tttactttcc
    33061 aattaggttg gaactacgaa cgtatgcaag cttctggtta cctttacatg atcttgcctc
    33121 agttgcgtaa aatgtatggt gatggaactc ctgaattgaa agaaatgatg aaagttcata
    33181 ctcaattctt caatacttca ccattcttcc ataccattat cgctggtttt gaccttgcca
    33241 tggaagaaaa agatggtgta ggttcaaaag acgctgttaa cggtatcaag acaggtttga
    33301 tgggaccatt cgctcctctt ggggatacaa tctttggttc acttgtacct gctatcatgg
    33361 ggtcagtcgc agcaactatg gctatcgctg gccaaccttg ggggatcttc ctttggattg
    33421 cagttgcagt agcgtatgac atcttccgtt ggaaacagtt ggaatttgct tacaaagaag
    33481 gggttaacct tatcaacaac atgcaaagta ccttgacagc tttgattgac gctgcatctg
    33541 tacttggtgt cttcatgatg ggtgctcttg tagcaacagt gattaacttt gaaatttctt
    33601 acaagttgcc aatcggtgaa aagatgattg atttccaaga catcttgaac caaatcttcc
    33661 cacgtttgct tccagcaatc tttactgcct ttatcttctg gttgcttggt aaaaaaggta
    33721 tgaactctac taaagctatc ggtattatta tcgtacttgc tttggctctt tctgcccttg
    33781 gtcactttgc acttggaatg taattcctta tgactaaatc attaattttg gtgagccatg
    33841 gtcgcttctg tgaggagctt agaggtagca cagaaatgat tatgggccca caagacaaca
    33901 tttacacagt agctcttctt ccagaagatg gcccagaaga atttactgct aaatttgaag
    33961 ctgttattga aggattggat gatttcctag tctttgcgga tcttctcggt gggacacctt
    34021 gtaatgtggt gagtcgcttg atcatggaag gtcgtgatat tgacctttac gcagggatga
    34081 atcttccaat ggtgattgaa tttatcaatg cgagccttac aggcgcagat gcggactaca
    34141 agagccgtgc tgcagaaagc attgtgaaag ttaatgacct gttagcgggc ttcgatgatg
    34201 acgaagatga ataatactct tcgaaaatct cttcaaacta cgtcaacgtc gccttgccgt
    34261 aggtatatgt tactgacttc gtcagtctta tccggcaacc tcaaaacggt gttttgagct
    34321 gacttcgtca gtcttatccg gcaacctcaa agcagtgctt tgagcagcct gcggctagtt
    34381 tcctacagat tttagttgga actcgattca attcatgtga caacgtgaaa atcgttagag
    34441 cattttatat agaatataca tgggaatgga gcttactccc attcccatat ttaatagaaa
    34501 aagaggaact caatgctaca ttatacaaaa gaagacttgc tcgaattggg tgcagaaatc
    34561 actacgcgtg aaatctacca acagcctgat gtatggagag aagcttttga attttatcaa
    34621 gcaaaacgtg aagaaattgc agcctttcta caagaaatcg ctgataaaca tgactatatt
    34681 aaggttatct tgacaggtgc tgggacttct gcttatgtgg gagatacctt gctaccttac
    34741 tttaaggaag tctatgacga acgcaaatgg aatttcaatg ctattgcgac aacagatatc
    34801 gttgccaaac cagcaaccta tttgaaaaaa gatgtggcaa ctgtccttgt gtcttttgct
    34861 cgtagtggga actcgcctga aagtgtggcg actgttgatt tggccaaatc cttggtggat
    34921 gagctttatc aagtgacgat tacttgtgca gcagatggta aattggctct tcaagctcac
    34981 ggtgatgacc gtaatctctt gctcttgcaa ccagctgtct ctaatgatgc tggatttgcc
    35041 atgacttcta gctttacgtc tatgatgttg acaactctct tggtctttga tcctacagaa
    35101 tttgctgtta agtctgaacg ttttgaagtt gtatctagtc ttgcccgtaa agttttagac
    35161 aaggcagaag atgtcaaaga gctcgttgat ttagacttta accgtgtcat ctatctaggc
    35221 gctggtcctt tctttggact tgctcatgaa gctcagctca agattttgga attaactgct
    35281 ggtcaagttg cgaccatgta tgaaagccca gttggcttcc gtcacggtcc aaaatctctt
    35341 atcaacgaca atacagttgt tttggtcttt ggtacaacga cggactacac tcgtaagtac
    35401 gacttggact tggttcgtga agttgctggt gaccagattg ctcgtcgtgt tgtgcttttg
    35461 agtgatcaag cttttggtct tgaaaatgtc aaagaagtgg tccttggttg tggcggtgtc
    35521 ttgaatgata tttaccgtgt cttcccttac atcgtttatg cccaactctt tgccctattg
    35581 acttcactca aggtagaaaa taaaccagat acaccgtctc ctacaggtac agtaaaccgt
    35641 gtagtacaag gtgtcataat tcacgaatat caaaagtaag acagtgttta tgaattcttg
    35701 acaagaggat ttgtaaatta tcagataaac catagattgt cagtacgctt tctatggttt
    35761 gtttgcttga gagaaatagt aaaaggagaa cagaatgaaa gcatacacag agcgtgtatt
    35821 tggaaatgtt gagggtgagg atgtcttggc ctatcgattt gagacagacg gtggctacca
    35881 acttgaggtt atgacttatg gtgcgactat cttgcgctat gtcgcacctg acaaggctgg
    35941 aaattttgcc aatgttatct tgggatttga tgactttgat agttatgtag gcaatagtcc
    36001 caagcatgga gcaagtgtag gtcctgtagc gggtcgtatt gcaggtgcga cctttgagct
    36061 caatggtaag acctatgacc ttgaggttaa taatgctagc aactgtaatc acagtggttc
    36121 aactggttgg gattccagct tgtttgaagt tgaagaagta agcgatcatg gcttgactct
    36181 ctacacagag cgtacagatg ggacaggagg gttccctgga aatctcaaga tttggatcag
    36241 ttatcacttg gaagaaactg gtgcctatga aatcagctac aaggtaacga ccgatcagga
    36301 tacgctggtc aatccaacca accacagcta tttcaacttg tctggtgatt tcacgcagac
    36361 gattgaccgt catgtcttcc aactaaacac agagggcatt tactcaatcg ctcctgacgg
    36421 tgttcctgcc aaaactccag aagccaaccg tgatgtggtc aaacacatct acaatggtgc
    36481 cttgttgaag gatatctttg cagaagaaga tgagcaaatc cagctggcat caggtttgga
    36541 tcatccattt gcccttcctg caggccatga caatgctgga ttcctttatg accaaaattc
    36601 aggtcgcttc ctgcttttca agacagaagc tccttgcttt gtggtctaca cagcaaactt
    36661 tgtggatgaa agtgtcatca taggaggtca gccaatgcta cagcacaatg ggattgctct
    36721 tgaagcgcaa gctttaccag atgccattca cagtgacctt aaaggccaag tcattcttaa
    36781 agctggtcaa accttcacca gtaagacacg ttatgaactt gttgtgaaat aaaaaaagct
    36841 ggtcaaaaag tctttaaaat taaaataacg catattgtca ggtgatgaaa agtttgataa
    36901 tatgcgtttt attatgaaat gatttacttt atattatcct gaaatggtgt tatttttgag
    36961 ttatctggct tgactttctt gatggaaatt atataatagt tgtaacaatg ataattacaa
    37021 ctagaaaaga ggaccattta tgacctatga atacaagagt cacatttatt tggcagagac
    37081 agctttaaat gtaaaggatt tggccagtca aacagccttt tatcagcaag ttattggttt
    37141 agaaatctta tctcaaactg agacagagtc cattctaggc cttggtggaa aagtcttggt
    37201 acagctgatt caagcacaag agagcggaga agtgagggaa tattatggtc tttaccattt
    37261 ggccattctc ttgcccacac gcaaggcttt agctgatgtc ttgaaacacc tgacagattt
    37321 acaaattcct cttgtcggcg gtgcagacca tggttacagt gaagctattt acttggaaga
    37381 tttggaggga aatggcattg aactctatcg agataagcca gtttccacat gggatattcg
    37441 agaagatgga cgcattatcg gagtgacaga ggctcttgcg gcgcaggaca tttatgagtt
    37501 gggggaaaga gtagagccct ttatcctggc agaaggtacg agaatggggc atattcatct
    37561 ttccgtcaag gatagtcgaa agtccagcca gttttatcaa aaggtgttag ggctagagga
    37621 taaattcagt gtgcctagcg ctagttggat tgcggctgga gattaccatc atcatttagc
    37681 agttaacgaa tggggaggaa aaggtctggc ttcgcgtaag caaggcttac caggtttagc
    37741 ctactatgtc atcgaagtcg cacacaaaaa agaactatta acgattgccc aacgagcaca
    37801 agaagttgac gcaccaatca aatggatgac atcgagccaa ttggaaatca cagactcaga
    37861 tggcatcgtg acccgtattc gtttagcaag gtaaaattag gaatttttaa taagttataa
    37921 gtattgctag tttgcttttt gaacggtctt tggtaacaga actgcgtgag ctggatgggc
    37981 gagaattttg acaaagaagc tgattagaga tataatgaag aaaaatcgag caaggaaaaa
    38041 gaaatgacaa attcaaagta tattacttgt ttgaaacgtt cagagggcca gttgtgtggg
    38101 attcaaaaga tgattgaagg agatcgtgac tgtgctgata ttgtgacgca actgacagca
    38161 gtgagatcta gtgtagagcg cgtgattgag atgataatta ccgaaaatct tactgaatgt
    38221 atcaatcagc cactagatga ttctgaagct caaaaggaac gcttagaaaa ggctatccga
    38281 tacttgatta aacggaaata aatgaatgtt ttgagacgat atgtgcaaag gtctattaac
    38341 tattagaata gtttaatggg agtcaaaaga agttgtaaaa aatctttaaa attaaaaaaa
    38401 cgcatagtat caggtattga aatgtactga ccccaaaaag ttagattttt tctgtctaac
    38461 ttttggggtg cagttcataa gaaccttggt aatatgcgtt ttattatggg gagatttata
    38521 cttttcgaaa atctcttcaa accaggtcag cttcaccttg ccgtagatat ggttactgac
    38581 ttcgtcagtt ctatccacaa cctcaaaaca gtgttttgag ctgacttcgt cagttccatc
    38641 cacaacctta aaacagtgtt ttgagctgac ttcgtcagtt ccatccacaa ccttaaaaca
    38701 gtgttttgag cagcctgcgg ctaacttcct agtttgcact ttaattttca ttgagtatta
    38761 cttcatcttc tcatgaaatt gagtttttgc ccagttcctc ttgattattc tacttgacca
    38821 ggccaagcat tcataccacc ttctacgttg gtaacggtga ggccttggga gatgagaaat
    38881 tggcaggtag atgcagagcg gactcctcct tgacaaataa catagtattc atggtcaggt
    38941 ttgagttctt tgtagccttg ctctaaggta cttaatggaa gatttttggc acctggtgca
    39001 tgtcctgctt ggaattcatg tgcttcacgg acatcgataa gttctagatt ttcattttgg
    39061 tattttccat aaaagtcagc catgctgata ctagtttcca tattctactc cttctgggtt
    39121 aaccattttg tatagtgaat aagcgccgtc aaggttttgg gcggtaaatc ctgcttgctt
    39181 gaggataggc tctgcgatat agctgcgcaa accactgtgg cagctgacga tgtaggcttg
    39241 ttttttgtcc agttcatcag cttcctcctt gacactttgt cagtttttga tacaatagta
    39301 caaaattaga ggaggtgggc tatgattcag aaacatgcga ttcctatttt agagtttgat
    39361 gacaatcctc aggcggttat catgcccaat cacgaggggc tggacttgca gttgccaaag
    39421 aagtgtgttt atgcattttt agatgaggag attgaccgct atgcaaggga agtaggggcg
    39481 gattgtgtcg gcgaattcgt ttctgctacc aagacctatc cagtctatgt catcaactac
    39541 aagggtgagg aggtctgtct ggctcaggct cctgttggct ccgctccagc agcccagttt
    39601 atggattggt tgattggcta tggtgtggag cagattatct ctactgggac ctgtggtgtt
    39661 ctagctgata tagaggaaaa tgcctttcta gtccctgttc gcgctctgcg agatgaagga
    39721 gccagttacc actatgtggc accttctcgt tatatggaaa tgcagccaga ggctattgct
    39781 gctattgagg aagttttgga agacagaggg attccttatg aagaagtcat gacctggacg
    39841 acagacggtt tttaccgaga aacggctgaa aaggtggctt atcgtaagga agaaggctgt
    39901 gctgttgtgg agatggagtg ttctgctctt gcggcagtag ctcaattgcg tggggttctc
    39961 tggggtgaat tgttgttcac agcagattct ctagcggact tggaccagta cgacagtcgt
    40021 gactggggct cggaagcttt taataaggcg ctagaactga gtttagcaag tgttcaccac
    40081 ctttagttgt actggcaaag gatttgtttt atcataaaat gtctagctca tacttttcaa
    40141 aaatatgttt aaacgaggtc accttcctct tgtcctaagc atgttgaggt tgggaaaaat
    40201 ctttaaaatc agaaaaacgt atcatatcag gtgatgaaaa ccttgatact atgcgtttta
    40261 tgttggtaag atttagagtg agatgaaatg atactcttcg aaaatctttt caaaccaggt
    40321 cagcttcacc ttgccgtagg tatatgttac tgacttcgtc agtcttatcc ggcaacctca
    40381 aaacggtgtt ttgagctgac ttcgtcagtt ctatttgcaa cctcaaaaca gtgttttgag
    40441 caatctgtga ctagctttct aatcgatgcc ttggttctca ttgcctataa tcaaaaagag
    40501 aaattttctc ctgaaaagca tatagagtag ctggcgttaa aagctcctgt cttgcttttt
    40561 tgacctatag tcacatctat caagtattgt tcttgcctaa gctatcaata aaaaggtggc
    40621 attttttagg cttggtgtta gtagattttg ccttatccta tctaagtcat ttcgaacttt
    40681 ttatggtaca atggaaacat gttattcaaa ttatctaagg aaaaaataga gctaggctta
    40741 tctcgtttat cgccagcccg tcgtattttt ttgagttttg ccttggtcat tttactaggc
    40801 tctcttcttt tgagcttgcc ctttgtccaa gttgaaagct cacgagcgac ttattttgat
    40861 catcttttca ctgctgtctc tgcagtctgt gtgacaggtc tctcaaccct tccagtagct
    40921 cacacctata atatatgggg ccaaataatc tgtttgctct tgattcagat cggtggtcta
    40981 gggctcatga cctttattgg ggttttctat atccagagca agcaaaagct tagtcttcgt
    41041 agccgtgcaa ctattcagga tagttttagt tatggagaaa ctcgatcttt gagaaagttt
    41101 gtctattcta tttttctcac gacctttttg gttgagagct tgggagctat tttgcttagt
    41161 tttcgcctta ttcctcaact tggctgggga cgtggtcttt ttagttccat ttttctagcg
    41221 atctcagcct tctgtaatgc cggttttgat aatttaggga gcaccagttt atttgctttt
    41281 cagaccgatt tactggtcaa tctggtgatt gcaggcttga ttattacagg cggccttggt
    41341 tttatggtct ggtttgattt ggctggtcat gtaggaagaa agaaaaaagg acgtctgcac
    41401 tttcatacga agcttgtact attgttgact ataggtttgt tgttatttgg aacggcaact
    41461 actctctttc ttgagtggaa caatgctgga acgattggca atctccctgt tgccgataag
    41521 gttttagtta gcttttttca aacagtgacg atgcgaacag ctggcttttc tacgatagat
    41581 tatactcagg ctcatcctgt gactcttttg atttatatct tacagatgtt tctaggtggg
    41641 gcacctggag gaacagctgg gggactcaag attacgacat tttttgtcct cttggtcttt
    41701 gcacgaagtg agcttctagg cttgcctcat gccaatgttg cgagacgaac gattgcgccg
    41761 cgaacggttc aaaaatcctt tagtgtcttt attatctttt tgatgagctt cttgatagga
    41821 ttgattctgc tagggataac agccaaaggc aatcctccct ttatccacct catatttgaa
    41881 accatttcag ctcttagtac agttggtgta acggcaaatc tgactcctga ccttgggaaa
    41941 ttggctctca gtgttatcat gccacttatg tttatgggac gaattggtcc cttgaccttg
    42001 tttgttagct tggcagatta ccatccagaa aagaaagata tgattcacta tatgaaagca
    42061 gatattagta ttggttaaga aaggaaagag catgtcagat cgtacgattg gaattttggg
    42121 cttgggaatt tttgggagca gtgtcctagc tgccctagcc aagcaggata tgaatattat
    42181 cgctattgat gaccacgcag agcgcatcaa tcagtttgag ccagttttgg cgcgtggagt
    42241 gattggtgac atcacagatg aagaattatt gagatcagca gggattgata cctgcgatac
    42301 cgttgtagtc gcgacaggtg aaaatctgga gtcgagtgtg cttgcggtta tgcactgtaa
    42361 gagtttgggg gtaccgactg ttattgctaa ggtcaaaagt cagaccgcta agaaagtgct
    42421 agaaaagatt ggagctgact cggttatctc gccagagtat gaaatggggc agtctctagc
    42481 acagaccatt cttttccata atagtgttga tgtctttcag ttggataaaa atgtgtctat
    42541 cgtggagatg aaaattcctc agtcttgggc aggtcaaagt ctgagtaaat tagacctccg
    42601 tggcaaatac aatctgaata ttttgggttt ccgagagcag gaaaattccc cattggatgt
    42661 tgaatttgga ccagatgacc tcttgaaagc agatacctat attttggcag tcatcaacaa
    42721 ccagtatttg gataccctag tagcattgaa ttcgtaaaga gggatgaccc ctcttttttg
    42781 atgcccaaga tggcaaatag agacagaagc cccttgtctt ctagtaaaag ttcttcaaag
    42841 gctggacttt atggtaaaat agaaggaagt gacaagagag agtaatactc aatgaaaatc
    42901 aaagatcaaa ctaggaaact agctgcgggc tgctcaaaac actgttttga ggttgtggat
    42961 agaactgacg aagtcagctc aaaacactgt tttgaggttg cagatagaac tgacgaagtc
    43021 agtaacatct atacggcaag gcgacgttga cgcggtttga agagattttc gaagagtata
    43081 agaaaaaatc agtcccctaa aggagcagat tatgaagtta ttgtctatcg ccatttctag
    43141 ctataatgca gcagcctatc ttcattactg tgtggagtcg ctagtgattg gtggtgagca
    43201 agttgggatt ttgattatca atgacgggtc tcaggatcag actcaggaaa tcgctgagtg
    43261 tttagctagc aagtatccta atatcgttag agccatctat caggaaaata aatgccatgg
    43321 cggtgcggtc aatcgtggct tggcagaggc ttctgggcgc tattttaaag tagttgacag
    43381 tgatgactgg gtggatcctc gtgcctactt gaaaattctt gaaaccttgc aggaacttga
    43441 gagcaagggt caagaggtgg atgcctttgt gaccaatttt gtctatgaaa aggaaggtca
    43501 gtctcgtaag aagagtatga gttacgagtc agtcttgcct gttcggcaga tttttgacta
    43561 ggaccaggtc ggaaatttct ccaaaggcca gtatatcatg atacactcgc tgatttatcg
    43621 gacagatttg ttgcgtgcta gccagttcta actgcctgaa catacttttt atgtcgatga
    43681 tctctttgtc tttacgcccc ttcagcaggt caagaccatg tactatctgc ctgtcgattt
    43741 ctatcgttat ttgattgggc gtgaggacca gtctgtcaat gagcaagtga tgattaagcg
    43801 cattgaccag caactcaagg tcaatcgact cttggtagac cagcttgatt tgtcccaagt
    43861 gagtcatcct aaaatgcgag aatatctgct gaatcatatt gaaatcacga cggtgatttc
    43921 cagtaccctg ctcaaccgat ctgaaacagc ggagcatctg gcaaaaaaac gccaattgtg
    43981 gacctatatt cagcagaaaa atccagaagt ctttcaggct attcgtaaga ccatgttgag
    44041 ccgtttgacc aaacattctg tcttgccaga tcgcaaactg tccaatgtcg tctatcaaat
    44101 caccaaatct gtttatggat ttaattaata taagtgtttt ataagaggga tttaagaaaa
    44161 attttaactt tttcttagtc ctttttaatt tcaggagatt atactagagt catcaaataa
    44221 agaaagactc taaggagaat cctatgaaat tcaatccaaa tcaaagatat actcgttggt
    44281 ctattcgccg tctcagtgtc ggtgttgcct cagttgttgt ggctagtggc ttctttgtcc
    44341 tagttggtca gccaagttct gtacgtgccg atgtggtcaa tccgacccca ggtcaagtct
    44401 tacctgaaga gacatcggga acgaaagagg gtgacttatc agaaaaacca ggagacaccg
    44461 ttctcactca agcgaaacct gagggcgtta ctggaaatac gaattcactt ccgacaccta
    44521 cagaaagaac tgaagtgagc gaggaaacaa actcttctag tctggataca ctttttgaaa
    44581 aagatgaaga agctcaaaaa aatccagagc taacagatgt cttaaaagaa actgtagata
    44641 cagctgatgt ggatgggaca caagcaagtc cagcagaaac tactcctgaa caagtaaaag
    44701 gtggagtgaa agaaaataca aaagacagca tcgatgttcc tgctgcttat cttgaaaaag
    44761 ctgaagggaa aggtcctttc actgccggtg taaaccaagt aattccttat gaactattcg
    44821 ctggtgatgg tatgttaact cgtctattac taaaagcttc ggataatgct ccttggtctg
    44881 acaatggtac tgctaaaaat cctgctttac ctcctcttga aggattaaca aaagggaaat
    44941 acttctatga agtagactta aatggcaata ctgttggtaa acaaggtcaa gctttaattg
    45001 atcaacttcg cgctaatggt actcaaactt ataaagctac tgttaaagtt tacggaaata
    45061 aagacggtaa agctgacttg actaatctag ttgctactaa aaatgtagac atcaacatca
    45121 atggattagt tgctaaagaa actgtcgaaa aagctgttaa agataacgtt aaagacagta
    45181 tcgatgttcc agcagcctac ctagaaaaag ccaagggtga aggtccattc acagcaggtg
    45241 tcaaccatgt gattccatac gaactcttcg caggtgatgg catgttgact c
//
LOCUS       DAVBIC010000011        43021 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.011, whole genome shotgun sequence.
ACCESSION   DAVBIC010000011 DAVBIC010000000
VERSION     DAVBIC010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 43021)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43021)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43021
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.011"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            1..779
                     /locus_tag="VQ664_000574"
                     /pseudo
     CDS             1..779
                     /locus_tag="VQ664_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(827..3370)
                     /locus_tag="VQ664_000575"
     CDS             complement(827..3370)
                     /locus_tag="VQ664_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HET2788792.1"
                     /translation="MKSFLKTYRTYFISFIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSSLFYTFTSGLGLNFYALSSYYLGSFLAPLVYFFDLTNMP
                     DAVYLTTLLKFGLIGLSTFFSLNKLFQSIPQTLKLALSTSYALMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLFPFILTILFFTLKSIKFHVKLIYVIFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVAGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSAYSRDIPAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVNFDY
                     FSPIPYEKTENTNDLISVTSSSNEDAAIQYQIEVPENSQVYLSFINLHFSNDKQKKVD
                     ILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTKTFT
                     EAIQKIKEQPVTVSTSKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQAQT
                     GFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(3432..5054)
                     /locus_tag="VQ664_000576"
     CDS             complement(3432..5054)
                     /locus_tag="VQ664_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2788793.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEEDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            5260..6285
                     /gene="trpS"
                     /locus_tag="VQ664_000577"
     CDS             5260..6285
                     /gene="trpS"
                     /locus_tag="VQ664_000577"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HET2788794.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            6438..7916
                     /gene="guaB"
                     /locus_tag="VQ664_000578"
     CDS             6438..7916
                     /gene="guaB"
                     /locus_tag="VQ664_000578"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HET2788795.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(7967..9064)
                     /gene="recF"
                     /locus_tag="VQ664_000579"
     CDS             complement(7967..9064)
                     /gene="recF"
                     /locus_tag="VQ664_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HET2788796.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSAQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSRSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKAAVNGN"
     gene            complement(9067..9435)
                     /gene="yaaA"
                     /locus_tag="VQ664_000580"
     CDS             complement(9067..9435)
                     /gene="yaaA"
                     /locus_tag="VQ664_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HET2788797.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKIDIPDMNIDILLTQSTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            9594..10844
                     /locus_tag="VQ664_000581"
     CDS             9594..10844
                     /locus_tag="VQ664_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HET2788798.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPVVVDNGFDPALFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSYLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHCPSKYGDEKHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSQLDLFSGFLRMYAGIDRENRNQARKMMNNQLLDL
                     KKGYFTELELEQTKEMIRRSLLLSQDNQSSLIERAYQNALLGKSSADFKSWIAKLEQV
                     DKDAICRAANNVKLQAIYFMEGIE"
     gene            10841..12124
                     /locus_tag="VQ664_000582"
     CDS             10841..12124
                     /locus_tag="VQ664_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HET2788799.1"
                     /translation="MTKVVFEEKYYPAVKEMVYRTRLANGLTVALLPKKEFKEVYGSV
                     TVQFGSVDTLVTEVDGDVKQYPAGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTNYLFSATDYFLENLDLLDELITSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKLTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSDRFQKCYESGKIDASLSLEVEITSRFHFVMLTMDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            12166..12987
                     /locus_tag="VQ664_000583"
     CDS             12166..12987
                     /locus_tag="VQ664_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET2788800.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            12998..13543
                     /gene="pgsA"
                     /locus_tag="VQ664_000584"
     CDS             12998..13543
                     /gene="pgsA"
                     /locus_tag="VQ664_000584"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HET2788801.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            13540..14367
                     /locus_tag="VQ664_000585"
     CDS             13540..14367
                     /locus_tag="VQ664_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HET2788802.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALALVGMLDFKKREPARLSGGQKQRVAIAGVVALRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSQNGYDLPENYLTESELEDKLWELL"
     gene            14352..15191
                     /locus_tag="VQ664_000586"
     CDS             14352..15191
                     /locus_tag="VQ664_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HET2788803.1"
                     /translation="MGIALENVNFTYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPNQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPAILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            15184..15978
                     /locus_tag="VQ664_000587"
     CDS             15184..15978
                     /locus_tag="VQ664_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HET2788804.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            16037..16855
                     /gene="mreC"
                     /locus_tag="VQ664_000588"
     CDS             16037..16855
                     /gene="mreC"
                     /locus_tag="VQ664_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HET2788805.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKVSQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            16855..17349
                     /gene="mreD"
                     /locus_tag="VQ664_000589"
     CDS             16855..17349
                     /gene="mreD"
                     /locus_tag="VQ664_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HET2788806.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            17443..18621
                     /locus_tag="VQ664_000590"
     CDS             17443..18621
                     /locus_tag="VQ664_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HET2788807.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            18845..19624
                     /gene="rpsB"
                     /locus_tag="VQ664_000591"
     CDS             18845..19624
                     /gene="rpsB"
                     /locus_tag="VQ664_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HET2788808.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNA"
     gene            19703..20743
                     /locus_tag="VQ664_000592"
     CDS             19703..20743
                     /locus_tag="VQ664_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HET2788809.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEGGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
     gene            20990..21331
                     /gene="tnpB"
                     /locus_tag="VQ664_000593"
                     /pseudo
     CDS             20990..21331
                     /gene="tnpB"
                     /locus_tag="VQ664_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
     gene            complement(21467..21754)
                     /locus_tag="VQ664_000594"
                     /pseudo
     CDS             complement(21467..21754)
                     /locus_tag="VQ664_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            21745..22143
                     /locus_tag="VQ664_000595"
     CDS             21745..22143
                     /locus_tag="VQ664_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2788810.1"
                     /translation="MKSPIPKAPLAHNFGSASIIAHTIHQKFNLKVPNYRQEEDWARM
                     GLPIIRKEISNWHIKTSQYYLEPLYNLLRERLLTQPLLHADETSYRVLESDSQLTYYW
                     TFLSGKAEKQGITLYHHVLIDLFISYFNPL"
     gene            complement(22340..23260)
                     /gene="cysK"
                     /locus_tag="VQ664_000596"
     CDS             complement(22340..23260)
                     /gene="cysK"
                     /locus_tag="VQ664_000596"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HET2788811.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKLGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLALAPDNGERYLSTALYEL"
     gene            complement(23545..24180)
                     /locus_tag="VQ664_000597"
     CDS             complement(23545..24180)
                     /locus_tag="VQ664_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HET2788812.1"
                     /translation="MEFRTIKEDGQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHDLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVSVNLV"
     gene            24236..25534
                     /locus_tag="VQ664_000598"
     CDS             24236..25534
                     /locus_tag="VQ664_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET2788813.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQAVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPTL
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLSLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLEEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVIEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            25531..26193
                     /locus_tag="VQ664_000599"
     CDS             25531..26193
                     /locus_tag="VQ664_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HET2788814.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQACQFWCKEGVEVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            26273..26821
                     /gene="raiA"
                     /locus_tag="VQ664_000600"
     CDS             26273..26821
                     /gene="raiA"
                     /locus_tag="VQ664_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HET2788815.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNIVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            26957..28930
                     /locus_tag="VQ664_000601"
     CDS             26957..28930
                     /locus_tag="VQ664_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HET2788816.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTALLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDATSESDISQINSFVANFISEFSEKYMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDQVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDALGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNTVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGRKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEIKEKEKEE"
     gene            28927..29379
                     /gene="rplI"
                     /locus_tag="VQ664_000602"
     CDS             28927..29379
                     /gene="rplI"
                     /locus_tag="VQ664_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HET2788817.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            29423..30775
                     /gene="dnaB"
                     /locus_tag="VQ664_000603"
     CDS             29423..30775
                     /gene="dnaB"
                     /locus_tag="VQ664_000603"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HET2788818.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            30777..31043
                     /locus_tag="VQ664_000604"
     CDS             30777..31043
                     /locus_tag="VQ664_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2788819.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            31132..32478
                     /gene="cbpD"
                     /locus_tag="VQ664_000605"
     CDS             31132..32478
                     /gene="cbpD"
                     /locus_tag="VQ664_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HET2788820.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSRG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEIPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRV
                     IKANTMTGFIHFKDLDGGSVGNSQSSTSTGGTHYFKTKSAIKTEPLVSATVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGNSVLSSTGGTHYFKTKSA
                     IKTEPLVSGTVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNY
                     QNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQT
                     GWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV"
     regulatory      32561..32663
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            32734..33024
                     /locus_tag="VQ664_000606"
     CDS             32734..33024
                     /locus_tag="VQ664_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-binding protein"
                     /protein_id="HET2788821.1"
                     /translation="MKASIALQVLPLAQGIDRIAVIDQVIAYLQTQEVTMVVTPFETV
                     LEGEFDELMRILKEALEVAGQEADNVFANVKINVGEILSIDEKLEKYTETTH"
     gene            32987..33745
                     /locus_tag="VQ664_000607"
     CDS             32987..33745
                     /locus_tag="VQ664_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2788822.1"
                     /translation="MRNLKSILRRHISLLGFLGVLSIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     NPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRT"
     gene            33783..34790
                     /locus_tag="VQ664_000608"
     CDS             33783..34790
                     /locus_tag="VQ664_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET2788823.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            34790..35518
                     /locus_tag="VQ664_000609"
     CDS             34790..35518
                     /locus_tag="VQ664_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2788824.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLDK"
     gene            35637..36095
                     /locus_tag="VQ664_000610"
     CDS             35637..36095
                     /locus_tag="VQ664_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HET2788825.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRELLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQVIQEVDRKGK"
     gene            36097..38529
                     /locus_tag="VQ664_000611"
     CDS             36097..38529
                     /locus_tag="VQ664_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HET2788826.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYEMDRLEEVALELTETDYSQDETFMELPFSRRLQVLFDEAEYVASVVHAKV
                     LGTEHVLYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALVLGLAQRIASGDVPAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     ALRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKVKYVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKI
                     GVKAGQLKFDIA"
     gene            39171..39824
                     /gene="rr06"
                     /locus_tag="VQ664_000612"
     CDS             39171..39824
                     /gene="rr06"
                     /locus_tag="VQ664_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HET2788827.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDETTQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDIWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            39821..41161
                     /gene="hk06"
                     /locus_tag="VQ664_000613"
     CDS             39821..41161
                     /gene="hk06"
                     /locus_tag="VQ664_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HET2788828.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDVYKEAKNILFLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGEVGKQINGMYEHLLKV
                     IHELESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIA
                     KSINKIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIEN
                     QLTDATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQE
                     LEHLFDIFYHSQIVTDKDESSGLGLYIVNNILESYQMDYSFLPYEHGMEFKISL"
     gene            41244..41771
                     /locus_tag="VQ664_000614"
     CDS             41244..41771
                     /locus_tag="VQ664_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HET2788829.1"
                     /translation="MVLAIILVTFFIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     MAHIVFYLSCLVEAMVHKTIFDGMGMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYVTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            41850..>43021
                     /locus_tag="VQ664_000615"
     CDS             41850..>43021
                     /locus_tag="VQ664_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RICH domain-containing protein"
                     /protein_id="HET2788830.1"
                     /translation="MFASKSERKVHYSIRKFSIGVASVVVASLFLGGVVHAEGVRSGD
                     TPKVTSSGDEVESHLKKILSEIQTQLDRKRHAKTVALINKLQDIKRTYSYKLNVLEEK
                     PKAELTSKTKEELTAAFEQFKKDTLPTEPGKKVAEAEKKVAEAEKKAEDQKEEDRRNY
                     PTNTYKTLELEIAEFDVKVKEAELELLKEKAKKPLNEGTIKQAKEKVESKKAEATRLE
                     NIKTDRKKAEEEAKRKAAEEDKVKEKPAEQPQPAPAPQPEKPAPKPEKPAPAPKPENP
                     AEQPKAEKPADQQAEEDYARRSEEEYNRLTQQQPPKTEKPAQPSTPKTGWKQENGMWY
                     FYNTDGSMATGWLQNNGSWYYLNSNGAMATGWLQNNGSWYYLNANGSMATGWLQNNG"
BASE COUNT        13618 a         7042 c         9263 g        13098 t
ORIGIN      
        1 acctactact atcacttgaa acagctagat aaaacagata aggaccaaga gcttaaagct
       61 gaaattcaat ccatctttat cgaacacaag ggaaattatg gttatcgtcg gatttattta
      121 gaactaagaa atcgtggtta tctggtaaat cataaaagag ttcaacactt gatgaagtac
      181 tcaatttaca agctaaaatg cgacagaaac gaaaatattc ttctcataaa ggagacgttg
      241 gcaagaaggc agagaatctc attcaaggcc aatttgaagg ctctaaaaca atggaacagt
      301 gctacacaga tgtgacagaa tttgccattc cagcaagtac tcaaaagctt tacttatcac
      361 cagttttaga tggctttaat agcgaaatta tcgcctataa tctttcaact tcacccaact
      421 tagaacaagt acaaacaatg ttggaacagg cattcacaga gaagcactac gagaatacga
      481 ttctccatag tgaccaaggc tggcaatatc aacacgattc ttatcatcag tttcttgagg
      541 gtaagggaat tcaagcatct atgtcacgca agggaaacag ccaagacaac ggtatgatgg
      601 aatctttctt tgggattctg aaatcggaaa tgttttacgg ttatgagaag agctttagat
      661 ctttagaaaa ccttgaacaa gctattgtgg actacattga ttactacaac aacaaacgaa
      721 ttaaggtaaa actaaaagaa cttagccctg tgcaatacag aactaaatcc ttcggataaa
      781 ttaattgtct aactttttgg ggtcagtaca ttaactggtc gattttttat gccttagatg
      841 actttcgtct gtgattatag attccaaata gtaagagaga agtaaaggaa cagattgctc
      901 cagtaataaa accattggga atgaaggaaa gtgtaatagt tcctttcccc ttgggaatgt
      961 caactttcat aaatccagtt tgagcttgtt taatttctat tttcttacca tcttggtagg
     1021 cagaccaacc tttgtcataa ggaatggtga agaaaataga tgtatcttgt tggacatcat
     1081 atgtagcaaa aaccttgttt ttagaagttg atactgtgac aggttgttct ttaatttttt
     1141 gaattgcctc ggtgaaagtt ttggtatcta aacgatagaa ggtaggagat tcaaatgata
     1201 cttgtgaatt tccagggaaa ctaacattga tattgaaagt ttttttctct ttagtatatc
     1261 ctagattaaa gaaggagaag acattatcag ttgtaaaagt ctttttttca ccatttacaa
     1321 ggatgtcaac cttcttttgt ttatcgttag aaaagtgaag gtttatgaaa gagagataaa
     1381 cttggctgtt ttctggaact tcaatttgat actggattgc tgcatcttca tttgaagaac
     1441 ttgtgacact aatcaaatca ttagtatttt ctgttttttc ataaggtatt ggagaaaaat
     1501 aatcaaaatt gacgttagca agttgattta aaaatgaggc ctgattatcc aaggtatgtt
     1561 cattgaactt gacatcattg taaacagatt gactagcaac tgcaatcgga agagagtatt
     1621 gattttcata tagggtaaga ttatcttttt gatagatatc tttaaagcca tacttatcaa
     1681 taggactgtc tgagatattg tactggatac caaataaact atcagccaaa atactattat
     1741 ttgcatatcg gagattgaga ttagtcccag aggatttaaa accaagttta tctaaagtag
     1801 agcttgatga acgatttcga acagatgaaa attgagagat tccattgtag ttgaatttca
     1861 tactgtcatt tcctgtctga gtttgtagtt tttcagtacg agtaaattga tttccaatat
     1921 atgttgagaa agattccata gctgggatat ctcgactata agcacttcga gaagcaaatc
     1981 cccattcctt agcaattccg tccatttgag atgaagcatt taaactcatt tcaaccagta
     2041 taaataaaga gattagaatg gcaaatagat tcacagatat aaactttttg ataactgcaa
     2101 ggagtaaaag agaatagaca accaaaaatt caagagtaag cagaatattc aaatctgtta
     2161 aaaaagaata atgcgatttt agatagatgg tagctaaaaa tcctgctact acaagaaaaa
     2221 gcgaaactaa aaaattccag actttaagtt ctttcagacg ctttaagact tctgctgctg
     2281 tgtaaattaa caaggtagag aaaatccaag catagcgatg taaaaacatg tttggagtat
     2341 gcatgccttg ccaaaataag tcaagagctt ctatgtaaaa gcttgcaatt agaaatgcaa
     2401 agaatattac atatatgagt ttcacgtgaa acttaataga tttcagcgta aaaaataaaa
     2461 tggtcaaaat aaagggaaat agtccaacaa aaatcattgg gatggcccca tactttgttg
     2521 tgtcaaagga accaatgaat tgcttagcaa agagatcaag ataccagcta ctttcagttt
     2581 gaaactttgt aacttcagtc aatttttccc catgtgtctg taaatcaaat agagtgggaa
     2641 gagtcataat caaactagcc ataccagcta aaaaggagat aactatgaaa tcaagaacag
     2701 atgattttcg agtcttaaag tcccacgaaa tttgacagag ataccagaaa ataagaaaca
     2761 atactgtcat atatccaaaa taataatttt gaataaataa gattgacaga cttgtaaagt
     2821 acaataggag tttcttttca gttatcagta gatgtaaacc agttataatt aaaggaatca
     2881 agataaaaac atctagccag gtttttatct ctaattgact gacagtgaaa ctcatcagag
     2941 cataggaagt agataaggct agttttaaag tctgagggat agattgaaac aatttattca
     3001 aactaaaaaa ggttgacaga ccaatcaatc caaattttaa gagagtggtc agatagacag
     3061 catctggcat attcgttaga tcaaaaaagt aaactagagg cgcgagaaaa ctacccaagt
     3121 aataactaga tagggcatag aagtttagcc ctagaccact tgtaaaggtg taaaacagac
     3181 tactatttcc atgtaggata tttcgtaagg ctacatcaaa aataacgtat tgatgaaagc
     3241 catctcctaa tagaggagag ttgtcgctat tccagtagat accttgagat agatatactc
     3301 cagacataat cactacagga atgatgaaag aaataaaata ggttcgatat gtttttaaaa
     3361 atgatttcat gttacctcgt agaatgatag aaaactcagt tggttaaccc aactgagttt
     3421 tgaagtttta tttagtcttt ccaaagttct ttaacttttg cttgtacttc tgcattttct
     3481 aggaattcat cgtaggtttc atcgatacgg tcaatgacgc catttttaga taagacaatg
     3541 atatggttag ccaaagtttg aataaactcg tggtcatggc tggcaaagat gattgattct
     3601 ttaaagtttt tcagtccatc attcaagctt gagatagatt ccaagtccaa gtgatttgtt
     3661 ggatcatcaa gtacaaggac atttgatttt aagagcatga gttttgaaag catgacacga
     3721 actttttctc cccctgacaa gacatttaca ggtttgttaa cttcatctcc agagaagagc
     3781 atacggccga ggaaaccacg taggaaagta ttgtcatctt cttctttact tgcgaattga
     3841 cgcaaccagt caagaattga ttctcctcct gcaaaatcag ctgagttatc ttttggtagg
     3901 taagattgac tagttgtaac tccccacttg acagttcctt catagtcaat atctcccatg
     3961 attgcacgaa ttaatgcagt cgtttgaata tcattttgtc caataagtgc tgtcttatca
     4021 tctggacgca agatgaaact aatattatcc aagatagttt caccatcaat ctttacagtt
     4081 agattttcta ctgtcaagag atcattacca atctcacgtt ccgctttaaa gttgataaat
     4141 ggatatttac gactagatgg tacaatctct tctagctcaa tcttatcaag cattttctta
     4201 cgtgatgttg cctgccttga cttagaagca ttggcagaga aacgagcaac gaattcttgc
     4261 aattgtttaa ttttttcttc tgctttagca ttacggtctg ctagcaattt agcagcaagc
     4321 tcagaagatt ccttccagaa gtcgtagttt ccgacataga gtttgatttt tccaaagtca
     4381 aggtcggcca tgtgagtaca aactttgttt aagaagtgac ggtcgtggga tactacgata
     4441 actgtgttat caaagtcaat caagaagtct tctaaccaag taatcgattg gatatccaaa
     4501 ccgttagtag gctcgtccaa gagaagaaca tctggtttac caaaaagtgc tttggcgagg
     4561 agaaccttta ctttttcacc gttggccaat tcgctcatgt tttggtagtg taattcttct
     4621 ggaatgttta ggttttgaag tagttgagag gcttcactct ctgcttccca acctccaagt
     4681 tcggcaaact ctccttcgag ttcggcagca cgaaccccgt cctcgtctga gaaatcttcc
     4741 ttcatgtaga tagcatcttt ctctttcatg atgctataaa gtttttcatt tcccatgata
     4801 acgacatcaa tggcacgttc atcttcgtag tcaaagtgat tttgacgaag aacagagaga
     4861 cgttcatctg gaccaagaga gatgtgacca gtagtaggtt cgatatctcc agctaaaatt
     4921 tttaaaaagg ttgattttcc ggcaccatta gcaccgatta atccgtaagt atttccttct
     4981 gtaaatttga tattgacatc atcaaaaagt ttgcgatcac taaaacgtag tgaaacatca
     5041 gatactgtaa gcaatgtttt tctcctatat gtgtaatata tttattctac tagaaaatac
     5101 agaaatattc aaatttttat ttgtcaattt tgtgtaaatt atatttacag tatcctttac
     5161 acaaatctgt aaaaagcaag gctgatttat tttgataaat tacggttatt tcattaaaaa
     5221 aatgctataa ttgaaaggac tatatcgaag gagaacaaaa tgactaaacc cattatttta
     5281 acaggagacc gtccaacagg aaaattgcat attggacatt atgttggaag tctcaaaaat
     5341 cgagtattat tacaggaaga ggataagtat gatatgtttg tgttcttggc tgaccaacaa
     5401 gccttgacag atcatgccaa agatcctcaa accattgtag agtctatcgg aaatgtggct
     5461 ttggattatc ttgcagttgg attggatcca aataagtcaa ctatttttat tcaaagccag
     5521 attccagagt tggctgagtt gtctatgtat tatatgaatc tagtttcgtt agcacgtttg
     5581 gagcgaaatc caacagtcaa gacagagatt tctcagaaag gatttggaga aagcattccg
     5641 acaggattct tggtctatcc aatcgctcaa gcagctgata tcacagcttt caaggctaat
     5701 tatgttcctg ttgggacaga tcagaaacca atgattgagc aaactcgtga aattgttcgt
     5761 tcttttaaca atgcatataa ctgtgatgtc ttggtagagc cggaaggtat ttatccagaa
     5821 aatgagagag cagggcgttt gcctggttta gatggaaatg ctaaaatgtc taaatcacta
     5881 aataatggta tttatttagc tgatgatgcg gatactttgc gtaaaaaagt aatgagtatg
     5941 tatacagatc cagatcatat ccgcgttgag gatccaggta agattgaggg aaatatggtt
     6001 ttccattatc tagatgtttt tggtcgtcca gaagatgctc aagaaattgc tgatatgaaa
     6061 gaacgttatc aacgaggtgg tcttggtgat gtgaagacca agcgttatct acttgaaata
     6121 ttagaacgtg aactgggtcc tattcgtgag cgccgtattg aatttgctaa ggatatggga
     6181 gaagtttata atatgattca aaaaggtagt gaaagagcgc gtgaagttgc gggtcaaacc
     6241 ctatctgagg taaaaggggc aatgggactt cattacttta actaagttta ttttacaaga
     6301 aactatcatt tctatctcga agaaaagata gtttttttat ttacccctgt aacatttgac
     6361 aaatttttat agaatggtat gatagataca atataaaaag agtcaagctc aaaaagaaag
     6421 aaaagaggaa acttcgaatg tctaattggg acactaaatt tttgaaaaaa ggttttacct
     6481 ttgatgatgt attgcttatt ccagctgaaa gtcatgtgtt gcctaacgat gcagatttaa
     6541 caactaaatt ggcagataat ttgactttaa atatcccaat tattaccgct gccatggaca
     6601 cagttacaga gagtcaaatg gccattgcta ttgctcgtgc aggcggtctc ggagttatcc
     6661 ataaaaacat gtcaattgct caacaagcag acgaggttcg taaggtaaaa cgttctgaaa
     6721 atggagttat tattgatccg ttcttcttga cgcctgaaca tacaattgct gaagcagatg
     6781 agcttatggg tcgttaccgc atcagtggtg ttccagttgt tgaaacactt gaaaatcgta
     6841 aattggttgg tattttgaca aaccgagatc ttcgttttat ttcagattat aatcaaccaa
     6901 tttcaaacca tatgactagt gaaaatcttg ttactgctcc tgtgggtacg gatcttgcaa
     6961 cggctgagag tattcttcaa gagcatcgta ttgaaaaact tccgttggtc gatgaagaag
     7021 gcagtctttc tggtttgatc actatcaaag atattgaaaa agttattgag tttccaaatg
     7081 cggctaaaga tgagtttggt cgtcttctag ttgcaggtgc agtaggtgtt acttcagata
     7141 catttgaacg tgcagaggct ctttttgagg caggagcgga tgcgattgtt attgatactg
     7201 cacatggtca ttctgcaggt gtcttgcgta aaattgccga gattcgtgct catttcccag
     7261 atcggacttt gattgctgga aatattgcta ctgctgaagg tgcacgtgcc ctttatgaag
     7321 cgggtgtaga cgttgttaag gttggtattg gaccaggttc tatctgtact actcgtgtga
     7381 ttgctggtgt tggtgttccg caagtaacag ctatctacga tgctgcagct gttgcgcgcg
     7441 aatatggtaa aacgattatt gctgacggtg ggatcaagta ttctggagat attgtaaaag
     7501 cacttgctgc aggtggaaat gctgttatgc ttggatctat gtttgctgga actgatgaag
     7561 ctccaggcga aactgaaatc ttccaaggac gtaaattcaa gacttaccgt ggtatgggat
     7621 caattgctgc tatgaagaaa ggttcaagcg accgttattt ccaaggttct gtcaatgaag
     7681 caaacaagct tgttccagaa ggaattgaag gtcgtgttgc ttataaagga gcggcagctg
     7741 atattgtttt ccaaatgatt ggtggtattc gctctggtat gggttactgt ggtgcagcta
     7801 accttaaaga actacacgat aatgctcaat ttattgaaat gtctggtgct ggtttgaaag
     7861 aaagccatcc tcatgatgtg caaattacta atgaggcacc aaattattct atgtaaaaaa
     7921 caatgaaaag aactccagtg aaaacaggag ttcttttaca atgttgtcaa tttccattta
     7981 cagcagcttt accatcctga atagtgaaga tacttagatt ttctggcaga ttttgaagat
     8041 ggtctaagct tgttgttgtg ataaaggttt ggattgattg agaaatcgtt tctaataatt
     8101 ttaactgtct agtgttgtca agttcactca tcacatcgtc aagcagtaat ataggagatt
     8161 ctgtggtaat gctttccatt aattcgattt ctgctaattt tatcgagagg acgagactac
     8221 gatgttgacc ttggcttccg aaactagcat ccatcccatt tatataaaaa gaaatgtcat
     8281 ctcgatgagg accgacacca gtattctttt taaataaatc tctggatcta cttttttcta
     8341 aagcaatttt gaaagattcg gataagtttt gtttgtcagt tatattgaca gaagattgat
     8401 aggatattga caactcttcg atctgattag agagttcaaa atgtttctta cgcccaaatg
     8461 attctagttt ttttatgaaa tctaagcggt gattcattac acgacatcca taatcaacta
     8521 gctgatcatc taacacagaa aggaatgttt catctatttt ttgagctgat tttaggtaag
     8581 tgtttctttg ctttaggatg tggttataat tggttaagtc agataaatag attggcttaa
     8641 tttgcccaag ttccatatca atgaattttc gtcgaatcga aggtgctcct ttaattagtt
     8701 gtaaatcttc aggagcaaat aagacaacat tcatgtgtcc tacataatct gaaaggcgtg
     8761 cctgttttaa gtgattaact tttgttacac ggcctttttg tgttagttcg atttctaggg
     8821 gaatggatcc agtttttttc tgaacgagac ctgaaagatg aagttgttcc tcatcaaaat
     8881 gaatgagatt tttatctgtt cgagttcgat gactacgcgt taaggctaaa aaatagatag
     8941 cctctaacat gtttgttttt ccttgtgcat tacgtcccaa aaagacattc aatttaggat
     9001 taaagtctat tttcgtttct ttgtaattac gaaaagtctt gagagataga tgttgtagcc
     9061 acatgattat ctaccaggga atcgtggagc ttgttggctt ttaggtgatg aagcaggttt
     9121 cgatttgtct tttttaactc ccttattcat ctttttgaca agtttagcga tccgttcttt
     9181 ttcaacttta tcagcttggt attcatcttg ttcttcagaa gtagattgtg tcaacaagat
     9241 gtcaatgttc atgtcaggga tgtcaatttt atcgccaata cgaagttttt taccacgacg
     9301 actctctaat tccctattaa agtaaacaga atgttcagag agaaatgatt taatagctcc
     9361 tccgctatgt gtaattccaa gttctttgag tagtgcttgg agggtaataa attcttcaaa
     9421 taatttgtat tccataattc acctcaatct ttggtattat accatatttt cctaaaaata
     9481 gtgagagata cagcgagaaa tgtaagcgat ttttatttca aaagtgttac agggaacaag
     9541 aaaatttcag gttttcgtga tataatagaa gtctgtatat aaggagataa atcatggagt
     9601 tagtgcatgg aatttcaaca cattttatcc aatcaaaaaa gtttaaaaca aacaaaatta
     9661 ccgtgcgttt taccgctcca ttatcccttg atacgattgc aggtcacatg ttgagtgcaa
     9721 gtatgctaga gactgctaat cagatgtacc ccacttctca agatttgagg agacacttgg
     9781 ccagtctata cggtacagat atgtcaacca attgtttcag aagagggcaa agccacatta
     9841 tagaattgac atttacctat gttcgtgatg agtttttaag taggaaaaac gtgctaactt
     9901 ctcagatttt ggaacttgta aaagaaactc ttttttcacc cgtagtagtt gataatgggt
     9961 ttgatccggc cttatttgaa attgagaaaa aacaattgct agcaagttta gcagctgata
    10021 tggatgattc tttttatttt gcacataaag aattggataa attgtttttt catgatgaac
    10081 gtcttcaatt ggaatatagt tatttacgaa atcgtatttt agctgaaact ccacaaagtt
    10141 cttattcttg tttccaagaa tttttagcca atgatcgaat agatttcttt ttcctaggtg
    10201 attttaatga ggttgaaatt caaaatgtat tagaatcatt tggctttaaa ggtcgaaaag
    10261 gagatgtgaa ggttcagtat tgtcaacctt attctaatat ccttcaggaa ggtatggttc
    10321 ggaaaaatgt gggacaatcc attttggaat taggttatca ttgcccttct aaatatggtg
    10381 atgagaaaca tttacccatg attgtaatga atggtttact tggtggattt gctcactcta
    10441 aactttttac aaatgtccgt gaaaatgctg gattagctta tactatttca agtcagctcg
    10501 atttatttag tggattcttg aggatgtatg ctggtattga ccgagaaaat cgtaaccagg
    10561 ctcgtaaaat gatgaataat caactgcttg atttaaaaaa aggttatttt acagagcttg
    10621 agttagagca gaccaaggaa atgattcgtc ggtctttgtt actttctcaa gataaccaat
    10681 cttcattgat tgaacgtgct tatcaaaatg ccttacttgg aaaatcttca gcagatttta
    10741 aaagttggat tgcaaaactc gagcaagttg acaaagatgc tatttgtaga gcagctaaca
    10801 atgtgaaact acaagcgatt tactttatgg aaggaataga atgacaaagg ttgtttttga
    10861 agaaaaatac tatccagctg taaaagaaat ggtttatcga actcgtttgg caaatggatt
    10921 gacagtagct cttttgccta aaaaggaatt taaagaggtt tacgggagtg taactgtaca
    10981 gtttggttcg gtagatacgc ttgtcacaga agttgatgga gatgtaaaac aatatcctgc
    11041 aggaattgct cattttcttg aacataaatt atttgaaaga gaagattcta gcgatttgat
    11101 gtcggctttt acgagtctag gtgcagatag taatgccttt acaagcttta caaaaacaaa
    11161 ctatcttttt tcagcaacgg attatttttt agaaaattta gatttacttg atgaattgat
    11221 aacatcagca cactttactg aagcttccat tctgacagag caggatatta ttcagcaaga
    11281 acgagaaatg taccaagatg atccagattc gtgtttattc ttttcaactt tagcgaattt
    11341 gtatcctggt acacctttag caactgatat agttggaagt gaggagtcca tttcccaaat
    11401 caatctaact aatttgcaag aaaattttac aaagttttac aaacctgtaa acatgtctct
    11461 gtttttagtt ggtaattttg atgtggagcg agtacaggac tattttgaaa gcaaagaact
    11521 gaaagattca gattttcagg aagtagcaag agaaaagttg tttttacagc ctgtaaagct
    11581 aacagatagt atgagaatgg aagtatcttc tcccaaacta gcgattggag ttagaggtaa
    11641 gcgagaagtt tctgaagcgg attgctatcg acatcatatt ttattaaaat tattgtttgc
    11701 aatgatgttt ggttggactt cggatcgttt tcaaaaatgt tatgaatcag gtaaaattga
    11761 tgcgtcctta tctctggaag ttgaaataac aagtcgcttt cattttgtca tgttgacaat
    11821 ggatacgaaa gagccagttg ctttgtctca tcaatttagg aaggctattc gtaattttac
    11881 aaaggattta gatattacag aggaacattt agatattatc aaaagagaga tgtttggcga
    11941 atttttcagt agcatgaact ctcttgaatt tattgcaacg caatatgatg cttttgaaaa
    12001 tggtgagaca atttttgatt tgccgaaaat tttacaggaa attactttag aggatgtcct
    12061 tgatgctgga catcatttaa tagatgatgg tgacatagtt gattttacaa tatttccatc
    12121 gtagtaacct atcataatag acactagaaa gaagggatga caagtatgag aaaaaaaaca
    12181 attggagagg ttttacgatt agctagaatc aatcagggat tgagtttaga tgaattgcag
    12241 aaaaagacag aaatccagtt agatatgttg gaagcaatgg aagcagacga tttcgatcaa
    12301 cttccaagtc ctttttacac gcgttctttc ttgaaaaaat atgcatgggc tgttgagtta
    12361 gatgaccaaa ttgttttgga tgcttatgat tctgggagta tgattactta tgaggaagta
    12421 gatgttgatg aagatgagtt gacaggtcgt agacgttcaa gtaagaaaaa gaagaaaaaa
    12481 acatcatttt tacctttatt ttattttatc ctttttgctt tatcgatttt aatttttgtg
    12541 acttattatg tttggaacta tattcaaact caaccagagg agccttctct ttctaattac
    12601 agtgtggttc aatcaacaag ttcaactagc tctgttcccc actcctcaag tagtagttct
    12661 tctagtatag aatcagctat aagtgtatca ggcgaaggaa atcatgtaga aatcgcttat
    12721 aagacaagta aggaaacagt taaattgcaa ttggcagttt cagatgttac aagttgggtc
    12781 agtgtttcag aaagcgaact tgagggcggt gtaaccttat cgccaaagaa gaaaagtgca
    12841 gaagcaacag ttgcaactaa aagtcctgta acaattacgt taggtgttgt aaaaggtgtt
    12901 gatttgacag tagataatca gactgttgat ttatcgaaat taacagctca gactggacaa
    12961 atcactgtaa cctttactaa aaattaagga aaaacgaatg aaaaaagaac aaattcccaa
    13021 tctcttaaca ataggtcgaa ttctctttat acctattttt atctttattt taacgatagg
    13081 aaattcgata gagagtcata tagttgcagc tattatcttt gctgttgcca gtattaccga
    13141 ctatttagat ggatatttag ctcgtaaatg gaatgtggtc agtaattttg gtaaatttgc
    13201 agatcctatg gcggataagt tactagttat gtcggctttt attatgttga ttgagttagg
    13261 tatggctccg gcttggattg ttgcagtgat tatatgtcgt gagttagctg tgacaggttt
    13321 aaggctttta ttggttgaaa ctggtggaac aattttagca gcagcaatgc ctggaaaaat
    13381 taaaactttt agtcagatgt ttgctattat tttcttgcta ttacattgga ctttgcttgg
    13441 tcaagttcta ctttatgtag ccttattttt cactatctac tctggctatg actattttaa
    13501 gggtagtgcc tatgtattta aagggacatt tggttcgaaa tgaaatcaat aattgatgta
    13561 aaaaatcttt cttttcgcta taaagaaaat cagaactact acgatgtgaa ggatattacg
    13621 tttcacgtga aacgtggaga atggctttcg attgtagggc ataatggtag tggtaaatca
    13681 acgacggttc gattaattga tggcttactg gaagcagaat ccggagagat tgtaattgat
    13741 ggccaacgtt tgactgagga aaatgtttgg aatatacgtc gtcaaatcgg tatggttttt
    13801 caaaatccag acaatcaatt tgttggagcg actgttgaag atgatgttgc ttttggtttg
    13861 gaaaatcagg gactttctcg tcaagaaatg aaaaagagag tggaagaagc tctggcttta
    13921 gttggcatgt tggactttaa aaagagagag ccagcgcgtc tatcaggtgg tcaaaagcaa
    13981 cgtgtggcca ttgcaggtgt tgtagcccta agaccagcta ttttaatctt agatgaagca
    14041 acgagtatgt tggatcctga ggggcgtaga gaacttattg ggacagtaaa aggaattcga
    14101 aaagactatg atatgacggt catttctatt acccatgatt tggaagaagt cgccatgagt
    14161 gatcgcgtat tggtcatgaa aaaaggggaa attgaatcaa ctagtagtcc aagggagctt
    14221 ttctctcgaa atgatttaga tcaaattgga ttagacgatc cttttgctaa tcaattaaaa
    14281 aaatctttga gccagaatgg ctatgattta cctgaaaatt atttgacaga aagtgagcta
    14341 gaggataagc tatgggaatt gctctagaaa atgtgaattt tacatatcaa gaaggtactc
    14401 ccttagcttc agcagctttg tcggatgttt ctttgacgat tgaagatggc tcttatacag
    14461 ctttaattgg gcacacaggt agtggtaaat caactatttt acaactctta aatggtttat
    14521 tggtgccaaa tcaagggagt gtgagggttt ttgatacctt aatcacctcg acttctaaaa
    14581 ataaagatat tcgtcaaatt agaaaacagg ttggcttggt atttcagttt gctgaaaatc
    14641 agatttttga agaaacggtt ttgaaggacg ttgcttttgg accgcaaaat tttggagttt
    14701 ctgaagaaga tgctgtgaag actgcgcgtg agaaactggc tctggttgga attgatgaat
    14761 cactttttga tcgtagtccg tttgagctgt cagggggaca aatgagacgt gttgccattg
    14821 caggcatact tgccatggag ccagctatat tagtcttaga tgagccaaca gctggtctag
    14881 atcctctagg gagaaaagag ttgatgaccc tgttcaaaaa actccaccag tcagggatga
    14941 ccatcgtctt ggtaacgcat ttgatggatg atgttgctga atatgcgaat caagtctatg
    15001 taatggaaaa gggacgttta gtaaaggggg gcaaaccaag tgatgtcttt caagacgttg
    15061 tttttatgga agaagttcag ttgggagtac ctaaaattac ggccttttgt aaacgattgg
    15121 ctgatagagg cgtgtcattt aaacgattac cgattaagat agaggagttc aaggagtcgc
    15181 taaatggata gtatgatttt agggcgttat atcccagggg attcgattgt tcaccgattg
    15241 gatccacgta gcaaattgct tgctatgatg ctactgattt tgattgtgtt ttgggctaat
    15301 aaccccttga cgaatctgat tctttttata gcgacaggga tatttattgc cttgtcagga
    15361 gtatctcttt cattttttat tcagggcttg aagtctatgt ttttcttgat tgccttcaca
    15421 actatttttc aactattttt catttctaat gggaatgttt tatttgagtt ttcgtttgtg
    15481 agaatcacgg attatgcttt gcaacaagct gggattattt tttgtcgctt tgtattgatt
    15541 attttctttt caactttgtt aaccttaaca accatgcctt taagtttggc atcagctgtc
    15601 gaagctttat tagcaccttt aaagcgtgtg aaagttccag ttcatgaaat tggattgatg
    15661 ctgtctatga gtttgcgttt tgtcccaacc ttgatggatg atacgactcg gattatgaat
    15721 gcacagaaag ctcgtggagt ggattttgga gaaggaagca tcgttcaaaa agtaaaggcg
    15781 atgattccca ttttgattcc tctttttgcg acaagtttaa aacgtgcaga ttccttggct
    15841 atcgctatgg aagcgcgtgg ctatcagggt ggaaaaggca gaagtcaata ccgacaattg
    15901 aaatggactc taaaggatac gctgaccatt cttgttattc tcgtacttgg ttgttgttta
    15961 tttttcttaa aatcttagta gctttcagga attgataaaa agttactgta acagtttttg
    16021 atataaaggt aggaatatga accgttttaa aaaatcaaaa tatgtcatta ttgtttttgt
    16081 cactgttctg cttgtgtcag ctctcttagc gacgacttat tcaagtacaa ttgtgacaaa
    16141 attaggagat ggaatctcat tggttgatag agttgtacaa aaaccttttc agtggtttga
    16201 ttctgtcaaa tcagatttgg ctcatttgac acgaacatat aatgaaaatg aaagtttgaa
    16261 gaaacagctt taccaattag aagttaaatc aaatgaggtg gaaagtttaa agacagaaaa
    16321 tgaacaactg cgccaattgc ttgatatgaa gtctaaattg caagccacaa agactttagc
    16381 agcagatgtt attatgcgtt ctccggtatc ttggaagcag gagttgacct tagatgcagg
    16441 tagatcaaaa ggtgcttctg agaacatgtt agctattgca aatggtggct tgattgggag
    16501 tgtttcaaaa gtagaggaga actctactat agtcaacctt ctgacaaata cggaaaatgc
    16561 tgataagatt tctgttaaaa ttcaacatgg ctctactaca atttatggaa ttattattgg
    16621 ctatgacaag gaaaatgacg ttcttaaagt tagccaatta aatagtaata gcgatattag
    16681 tgcgggagat aaggtgacta ctggtggatt aggaaacttt aacgttgctg atattcctgt
    16741 tggtgaagtg gttgccacaa cgcatagtac agactatttg acacgagaag taactgttaa
    16801 attgagtgca gatactcata atgtagatgt gatagaatta gtggggaatt cataatgaga
    16861 cagttgaagc gagttggagt atttttattg cttcctttct ttgttctaat tgacgcccat
    16921 attagccagc ttctgggctc atttttcccc catgtacatt tggctagtca ttttcttttt
    16981 ctatttctct tatttgagac gatagaagta tcagagtatc tctacctagt ctattgtttt
    17041 gttataggct tggtttatga tgtttacttt ttccatctaa tagggattac aactctctta
    17101 tttatcttat tgggagcctt ccttcataaa ttgaatagtg ttattttgtt gaatcgttgg
    17161 acaagaatgc tagctatgat tgtactgaca ttcctgtttg aaatgggtag ttatcttttg
    17221 gcttttatgg tagggttgac agtagatagc atgtcgattt ttatagtcta tagcttggta
    17281 ccgacgatga ttttaaattt tttatggatt actgtttttc aatttatttt tgaaaaatat
    17341 tatctataag aacgacatat aaatgtaaca aaggcgtaat atttattagg cctttttttg
    17401 gtatactagt attgtcttta aaagaaggag tatctacgta atatgaagaa aaaaatctta
    17461 gcgtcacttt tattaagtac agtaatggtt tctcaagtag ctgttttaac aactgcgcat
    17521 gcagaaacga ctgatgacaa aattgctgct caagataata aaattagtaa cttaacagca
    17581 caacaacaag aagcccaaaa acaagttgac caaattcagg agcaagtatc agctattcaa
    17641 gctgagcagt ctaacttgca agctgaaaat gatagattac aagcagaatc taagaaactc
    17701 gagggtgaga ttacagaact ttctaaaaac attgtttctc gtaaccaatc gttggaaaaa
    17761 caagctcgta gtgctcaaac aaatggagcc gtaactagct atatcaatac cattgtaaac
    17821 tcaaaatcaa ttacagaagc tatttcacgt gttgctgcaa tgagtgaaat cgtatctgca
    17881 aacaacaaaa tgttagaaca acaaaaggca gataaaaaag ctatttctga aaaacaagta
    17941 gcaaataatg atgctatcaa tactgtaatt gctaatcaac aaaaattggc tgatgatgct
    18001 caagcattga ctacgaaaca ggcagaacta aaagctgctg aattaagtct tgctgctgag
    18061 aaagcgacag ctgaagggga aaaagcaagt ctattagagc aaaaagcagc agctgaggca
    18121 gaggctcgtg cagctgcggt ggcagaagca gcttataaag aaaaacgagc tagccaacaa
    18181 caatcagtac ttgcttcagc aaacactaac ttaacagctc aagtgcaagc agtatctgaa
    18241 tctgcagcag cacctgtccg tgcaaaagtt cgtccaacat acagtacaaa cgcttcaagt
    18301 tatccaattg gagaatgtac atggggagta aaaacattgg caccttgggc tggagactac
    18361 tggggtaatg gagcacagtg ggctacaagt gcagcagcag caggtttccg tacaggttca
    18421 acacctcaag ttggagcaat tgcatgttgg aatgatggtg gatatggtca cgtagcggtt
    18481 gttacagctg ttgaatcaac aacacgtatc caagtatcag aatcaaatta tgcaggtaat
    18541 cgtacaattg gaaatcaccg tggatggttc aatccaacaa caacttctga aggttttgtt
    18601 acatatattt atgcagatta atttacagag ggactcgaat agagccctct tttcaggttt
    18661 taccgtgaca atccctatta aaaattatat caaaatagct tgaaaatatt ggaaaagtat
    18721 ggtaaaatga aaattgtcgt gtgaacgata atactcattc ttgatgaatt gtgaagcagt
    18781 tgcccttggg tcgttttgcg agttgaagtc aagaagagga aaaaaacaaa aaggagaaat
    18841 actcatggca gtaatttcaa tgaaacaact tcttgaggct ggtgtacact ttggtcacca
    18901 aactcgtcgc tggaatccta agatggctaa gtacatcttt actgaacgta acggaatcca
    18961 tgttatcgac ttgcaacaaa ctgtaaaata cgctgaccaa gcatacgact tcatgcgtga
    19021 tgcagcagct aacgatgcag ttgtattgtt cgttggtact aagaaacaag cagctgatgc
    19081 agttgctgaa gaagcagtac gttcaggtca atacttcatc aaccaccgtt ggttgggtgg
    19141 aactcttaca aactggggaa caatccaaaa acgtatcgct cgtttgaaag aaattaaacg
    19201 tatggaagaa gatggaactt tcgaagttct tcctaagaaa gaagttgcac ttcttaacaa
    19261 acaacgtgcg cgtcttgaaa aattcttggg cggtatcgaa gatatgcctc gtatcccaga
    19321 tgtgatgtac gtagttgacc cacataaaga gcaaatcgct gttaaagaag ctaaaaaatt
    19381 gggaatccca gttgtagcga tggttgacac caatactgat ccagatgata tcgatgtaat
    19441 catcccagct aacgatgacg ctatccgtgc tgttaaattg atcacagcta aattggctga
    19501 cgctattatc gaaggacgtc aaggtgagga tgcagtagca gttgaagcag aatttgcagc
    19561 ttcagaaact caagcagatt caattgaaga aatcgttgaa gttgtagaag gcgacaacgc
    19621 ttaatttata caaatagtaa ttacctagga gggcggggct tagcccggct ctcctatttt
    19681 caaaaaatat aggagaatta aaatggcaga aattacagct aaacttgtaa aagagttgcg
    19741 tgaaaaatct ggtgccggtg ttatggacgc taaaaaagcg cttgtagaaa cagacggtga
    19801 catcgaaaaa gcgattgaat tgcttcgtga aaaaggtatg gctaaggcag ctaagaaagc
    19861 tgaccgtgtt gctgcagaag gtttgactgg tgtttatgtt aacggtaatg ttgcagcagt
    19921 tattgaagta aacgctgaaa ctgacttcgt tgcaaaaaac gctcaattcg ttgaattggt
    19981 aaatactaca gctaaagtca ttgctgaagg aaaacctgct aacaacgaag aagctcttgc
    20041 tttgataatg ccttcaggtg aaactcttga agctgcatac gtatctgcaa cagcaactat
    20101 cggagagaaa atctcattcc gtcgctttgc attgattgaa aaaacagacg cacaacactt
    20161 tggagcatac caacataacg gtggacgtat cggtgttatt tcagttgttg aaggtggaga
    20221 cgaagcactt gctaaacaat tgtcaatgca catcgcagcg atgaaaccaa cagttctttc
    20281 ttacaaagaa ttggatgagc aattcgttaa agatgagttg gcacaattga atcacgttat
    20341 cgaccaagac aacgaaagcc gtgcaatggt taataaacca gctcttccac acttgaagta
    20401 tggatcaaaa gctcaattaa ctgatgatgt tattgctcaa gctgaagctg acatcaaagc
    20461 tgaattggct gcagaaggca aaccagaaaa aatctgggac aaaattattc caggtaaaat
    20521 ggatcgcttc atgcttgata acactaaagt tgaccaagct tacacacttc ttgcacaagt
    20581 ttacatcatg gatgacagca agacagttga agcatacctt gaatcagtta acgcttcggt
    20641 agttgagttt gctcgctttg aagttggtga aggtatcgag aaagctgcaa acgacttcga
    20701 agctgaagtt gcagctacaa tggcagcagc cttgaataac taataataga aaggaagcaa
    20761 attgcttcct tttttgtata gggcttagat ttttcctgaa attgtttttt ccccagtctc
    20821 actcgattag aataattaaa acaaaaagcc ctataataag ggctaagtgc atttaggaga
    20881 ctatacttca aattcatagt aagcgcgttc ataacaaggt atctatccta attccccaac
    20941 ttccagtata ctagataaaa aataattatc ggagtaaagg tattgtacta tgataattca
    21001 actaagtgat ttaggtcaag ttcaccttgt ttgtggcaag acagatatga ggtagggaat
    21061 agactcatta gcctatgtag ttaaaaccca ctttgaattg gattctttct ccggtcaagt
    21121 ctttctcttt tgtggtgaac gtaaagaccg ctttaaagcc ctttactggg atggtcaagg
    21181 attttggcta ctatataaac gctttgagaa cggaaaactg acttggctaa gtacagaaaa
    21241 ggatgtcaaa gctctcgcac ctgaacaagt agattggctt atgaagggct tttctatcac
    21301 tccaaaatat agtatattga aactagaata gtacacctct gcttctaaaa cattgttaga
    21361 aatcgatttg actgtcctga tcgatttatc ctgttcttat ttcattttac tataaatcta
    21421 tcagaaagtt gtgatttcta ttgaaatgag gactttcttt ttacactcat ctgctttcaa
    21481 aaagcattct agtccgtctc cgattaacga tggactttat cacctccttc tccagtcctt
    21541 gtatgacatc ttccaaagtt cgaaaggctt tattcttaaa tccacgttta cgaatctctt
    21601 tccacacttg ttcaatgggg ttcatctctg gtgtgtatgg aggaataaat gcaaagccaa
    21661 tattagtcgg aatctttaag gtacttgatt tatgccatat agcattgtcc ataacgagta
    21721 aaagataatc atctggataa gcttgtgaaa tctcctattc ctaaagcccc tttagcgcat
    21781 aactttggct cagcttctat tatcgctcac accatccatc agaagtttaa tctgaaggta
    21841 cccaattatc gccaagaaga agattgggct aggatgggtt taccaatcat acgtaaggaa
    21901 atctctaatt ggcatatcaa gacgagtcaa tactatttgg agccccttta taacctcttg
    21961 cgagagagac tattgactca gcccttactt catgcggatg aaacttctta tagggtgcta
    22021 gagagtgata gtcagctgac ttactactgg acttttttgt ctgggaaagc tgagaaacaa
    22081 gggattacgc tttaccatca tgtcctaatc gatttgttca tatcttattt caatccatta
    22141 taaatagtga gaaatatcta tcctatcttc tagaatgtct tccaaacgtg gaaactctcg
    22201 taaacaaaga ggttttagag gcctatttac catggactaa agttgtacaa gaaaagtgca
    22261 aataagaaat ctccagatta ggaactatcc gtgagttctc tagtctggag atttttcaat
    22321 agacttcgtt attggacggt tacaattcat aaagtgctgt agagagataa cgttcaccgt
    22381 tatctggtgc tagggcaagg acttttttac ctgtacctaa ttttttggca acctcgatgg
    22441 ctccgtagat agctgcagct gaggaaatcc ctacaaggaa gccttctttt ccaccaattt
    22501 cacgtccgag tgcaagagcg tcatctgatg ttacacgaac gataccatca taggctttag
    22561 tatcaagtgt atcaggaata aatccagctg agataccttg aattttgtga ggaccaggtt
    22621 tttcaccaga tagaatagca gattcatctg cttctactgc aaaaacttga atgttagaat
    22681 tttctgattt gagtgcatga gaaacaccag aaatcgttcc accagtacct actccagcaa
    22741 caaaggcatc taatccatct ttaccgaaag cagctagtat ctcagctcct gttgttcttt
    22801 cgtgtacttc tggattagct ggattgtcaa attgaagagg aaggaaacca tcacgttcag
    22861 cagcgatttc ttgagcctta gcaatagcac ctttcattcc ctcgctacca ggagttagga
    22921 cgagttcagc accataagct tggataattt tacgtcgttc tacactcata gtttcaggca
    22981 taacgatgac gactttatac cctttagcag cacctaccca tgaaagtcca ataccggtgt
    23041 ttccacttgt tgcttcaaca atagtagaac caagtttcag aataccatct tgttcagctt
    23101 tttcaatcat gctaagggca atacggtctt ttacagatga accaggatta aatgcttcaa
    23161 gctttatata gacgtctgca gcaccttctg gcacgatgtt gttaagttta acaatcggtg
    23221 tttgaccgat taattcagta atgttgttat aaatagacat atgaatacct ctttgtataa
    23281 gatatcttta gtataacgct atccatacca tttgtaaaat atagaaatcc tatcgaagcg
    23341 ataggatttc tatatatcat agatcaaagt cattaatttt caagtgattg cgttcagtta
    23401 attctagtaa ataggtgtga aggaaaacga tatcaggttt cgtttgaatt gcttcatttt
    23461 ctagtatatt ttggtacgca tctttttatt ttgctcgcta aagtagttgt gagaatgtca
    23521 acgaaacgct gtattattca ttgtttacac taagtttaca gaaacttcaa cctctcgtaa
    23581 accttggtca gttaaagtga cttttccatt aaaaaactcc acaagtgcag ctttaatagt
    23641 ttctttttct tctttatcaa cataaatcat cgtatcgact tgatctgtaa agtttgtatc
    23701 cagctccatg agatcatgtt ctttaaggaa gttactgtac tcttggtact gagcataaga
    23761 catttgaata gcaatgccag cctgttcttt tatttcaata ataccaattt ctttgacagc
    23821 taaggcgaca ctgccggcgt aagcacgaat tagtcctcca gcgcctagtt taataccacc
    23881 aaagtagcgt gtcacgacca cacagacatt ggtgagattg tgattttcta gtaccccaag
    23941 catgggaaca ccagcagtac cactaggctc accatcatca cttgtacgtt taatttcact
    24001 acgttctcca ataataaagg cagagcagtt atgtgtcgct ttgtagtgtt cttttttgat
    24061 ggcagtaatg aagtcacgag cctcttcttc gctataaaca cgcttggcat ggcagataaa
    24121 gcgagatttt ttgatttctt cttggacttg gccgtcctct ttaattgtcc taaattccat
    24181 gatttaattg tactaaaaaa taatctaaag tgctagtttt tacgaataaa gaagtatgaa
    24241 agtaaattta gattatctcg gtcgtttatt tactgagaat gaattaacag aagaagaacg
    24301 tcagttggcg gagaaacttc cagcaatgag aaaggagaag gggaaacttt tctgtcaacg
    24361 ttgtaatagt actattctag aagaatggta tttgcccatc ggtgcttact attgtcgaga
    24421 gtgcttgctg atgaagcgag tcagaagtga tcaaacttta tactattttc cgcaggagga
    24481 ttttccgaag caagatgttc tcaaatggcg cggccaatta actccttttc aagagaaggt
    24541 gtcagaggga ctgcttcaag cagtagacaa gcaaaagcca accttagttc atgcggtaac
    24601 aggagctgga aagacagaaa tgatttatca agtagtggct aaagtgatca atgcgggtgg
    24661 tgcagtgtgt ttggctagtc ctcgcataga tgtttgtttg gagctgtaca agcgcctgca
    24721 acaggatttt tcttgcggta tagctttgct acatggagaa tcggaacctt attttcgaac
    24781 accactagtt gttgcaacaa cccatcagtt attgaagttt tatcaagctt ttgatttgct
    24841 gatagtggat gaagtagatg cttttcctta tgttgataat cccacgcttt accacgctgt
    24901 caagaatagt gtaaaggaga atggattgag aatcttttta acagcgactt cgaccaatga
    24961 gttagataaa aaggtccgtt taggagaact aaaaagactg agtttaccga gacggtttca
    25021 tggaaatccg ttgattattc caaaaccaat ttggttatcg gattttaatc gctacttaga
    25081 caagaatcgt ttgtcaccaa agttaaagtc ctatattgag aagcagagaa agacagctta
    25141 tccgttactc atttttgctt cagaaattaa gaaaggggag cagttagaag aaatcttaca
    25201 ggagcaattt ccaaatgaga aaattggctt tgtatcttct gtaacagagg atcgattaga
    25261 gcaagtacaa gcttttcgag atggagaact gacaatactt atcagtacga caatcttgga
    25321 gcgtggagtt accttccctt gtgtggatgt tttcgtaata gaggccaatc atcgtttgtt
    25381 taccaagtct agtttgattc agattggtgg acgagttgga cgaagcatgg atagaccgac
    25441 aggagatttg cttttcttcc atgatgggtt aaatgcttca atcaagaagg cgattaagga
    25501 aattcagatg atgaataagg aggctggtct atgaagtgct tgttatgtgg gcagactatg
    25561 aagactgttt taacttttag tagtctctta cttctgagga atgatgactc ttgtctttgt
    25621 tcagactgtg attctacttt tgaaagaatt ggggaagaga actgtccaaa ttgtatgaaa
    25681 acagagttgt caacaaagtg tcaagcttgt caattttggt gtaaagaagg agttgaagtc
    25741 agtcatagag cgatttttac ttacaatcaa gctatgaagg attttttcag tcggtataag
    25801 tttgatggag acttcctgtt aagaaaagtt ttcgcttcat ttttaagtga ggagttgaaa
    25861 aagtacaaag agtatcaatt tgttgtaatt cccctaagtc ctgatagata tgctaacaga
    25921 ggatttaatc aggttgaggg cttggtagag gcagcaggct ttgagtatct agatttatta
    25981 gagaaaagag aagagagagc cagttcttct aaaaatcgtt cagagcgctt ggggacagaa
    26041 cttcctttct ttattaaaag tggagtcact attcctaaaa aaatcctact tatagatgat
    26101 atctatacta caggagcaac tataaatcgt gttaagaaac tgttggaaga agctggtgct
    26161 aaggatgtaa aaacattttc ccttgtaaga tgaggaaaaa atttgcaaaa atagaatgaa
    26221 agcgttataa taaaatcata aaaacaaaaa tgtttagaaa gaaggtactc atatgattaa
    26281 atatagtatc cgtggtgaaa acctagaagt aacagaagca attcgtgatt atgtagtttc
    26341 taaactcgaa aagatcgaaa agtacttcca accagaacaa gagttggatg cccgaattaa
    26401 cttaaaagtt tatcgtgaaa aaacggctaa agtggaagta acgattccgc ttggatctat
    26461 tactctccgc gcagaagatg tatctcaaga tatgtatggt tcaattgacc ttgtaactga
    26521 taaaattgaa cgtcagattc gtaaaaataa aacaaaaatc gagcgtaaaa ataaaaataa
    26581 ggtagcaact ggtcaattat ttacagatgc tttggtggaa gattcaaata ttgtccagtc
    26641 taaagttgtt cgttcaaaac aaattgattt aaaaccaatg gatttggaag aagcaattct
    26701 acaaatggat ttattggggc atgatttctt tatctatgtg gatgttgaag atcagacaac
    26761 caatgtgatt tatcgtcgtg aggatggcga aattggtttg ttagaggtta aagaatctta
    26821 atttcaatat gtgtaaaggt aggtttactg aattgtaaac tacctttttc ttataattga
    26881 tagaattact gattacactt ttaaaaagtc gctttttgag gggtattatg gtataatggg
    26941 tgccaagagg ttttgaatga aaaaatttta tgtaagtcca atttttccta ttctagtagg
    27001 attgattgcg tttggagtct tatccacttt cattattttt gttaataata atctgttgac
    27061 ggttttaatt ttgtttcttt ttgtaggagg ctatgttttt ttatttaaga aactgagagt
    27121 gcattataca aggagtgatg tagaacagat acagtatgta aaccaccaag cggaagaaag
    27181 tttgacagct ctattggaac agatgcctgt aggtgttatg aaattgaatt tatcttctgg
    27241 agaggttgag tggtttaatc cctatgctga attgattttg accaaggaag atggtgattt
    27301 tgatttagaa gctgttcaaa cgattatcaa ggcttcagta ggaaatccgt ctacttatgc
    27361 caagcttggt gagaagcgtt atgctgttca tatggatgct tcttccggtg ttttgtattt
    27421 tgtagatgta tccagggaac aagccataac agatgaattg gtaacaagtc gaccagtgat
    27481 tgggattgtc tctgtggata attatgatga tttggaggat gcaacttctg agtcagatat
    27541 tagtcaaatc aatagttttg tagctaattt tatatcagag ttttcagaaa aatacatgat
    27601 gttttctcgt cgggtaagta tggatcgatt ttatctattt actgactaca cggtgcttga
    27661 gggcttgatg aatgataaat tttctgttat tgatgctttc agagaagagt cgaaacagag
    27721 acagttgccc ttgaccttaa gtatgggatt ttcttatggc gatggaaatc atgatgagat
    27781 agggaaagtt gctttgctca atttgaactt ggctgaagta cgtggtggcg accaggtggt
    27841 tgttaaggaa aacgacgaaa cgaaaaatcc agtttatttt ggtggtgggt ctgctgcttc
    27901 aatcaagcgt acacggactc gtacgcgcgc tatgatgaca gctatttcag ataagattcg
    27961 gagtgtagat caggtttttg tagtcggtca caaaaattta gacatggatg ctttgggctc
    28021 tgctgtaggt atgcagttgt tcgccagcaa tgtgattgaa aatagctatg ctctttatga
    28081 tgaagaacaa atgtctccag atattgaacg agctgtttca ttcatagaaa aagaaggagt
    28141 tacgaagttg ttgtctgtta aggatgcatt ggggatggtg accaatcgtt ctttgttgat
    28201 tcttgtagac cattcaaaga cagccttaac attatcaaaa gaattttatg atttatttac
    28261 ccaaaccatt gttattgacc accatagaag ggatcaggat tttccagata atacggtcat
    28321 tacttatatc gaaagtggtg caagtagtgc cagtgagttg gtaacggaat tgattcagtt
    28381 ccagaattct aagaaaaatc gtttgagtcg tatgcaagca agtgtcttga tggctggtat
    28441 gatgttggat actaaaaatt tcacctcgcg agtaactagt cggacatttg atgttgctag
    28501 ctatctcaga acgcgcggaa gtgatagtat tgctatccag gaaatcgctg cgacagattt
    28561 tgaagaatat cgtgaggtca atgaacttat tttacagggg cgtaaattag gttcagatgt
    28621 actaatagca gaggctaagg acacgaaatg ctatgataca gttgttatta gtaaggcagc
    28681 agatgccatg ttagccatgt caggtattga agcgagtttt gttcttgcga agaatacaca
    28741 aggatttatc tctatctcag ctcgaagtcg tagtaaactg aatgtacaac ggattatgga
    28801 agagttaggc ggtggaggcc actttaattt ggcagcagct caaattaaag atgtaacctt
    28861 gtcagaagca ggtgaaaaac tgacagaaat tgtattaaat gaaataaagg aaaaggagaa
    28921 agaagaatga aagtaatctt tttagcagat gttaaaggaa aaggtaaaaa aggcgaaatt
    28981 aaggaagtac caacagggta tgcgcaaaac tttcttatca aaaagaatct agccaaagaa
    29041 gcgactgctc aagctgtagg tgaacttcgt ggtaaacaaa aatcggaaga aaaagctcac
    29101 gctgagatga ttgcagaagg aaaagcaatt aaagcacaac ttgaagcaga agaaactgtt
    29161 gtagaatttg ttgaaaaagt tggtccagat ggtcgtacct ttggctctat taccaataag
    29221 aagattgcag aagaattgca aaaacaattt ggaattaaga ttgataaacg tcatattcaa
    29281 gtacaagctc cgattcgagc ggttggtttg attgatgtgc cagtgaaaat ctatcaagat
    29341 atcacaagtg taatcaatct tcgtgtgaaa gaaggataag tttacacctt cttgacaaga
    29401 ttgtaaaagg aagggaagtc tgatggcaga agtagaagag ttacgagtac aacctcaaga
    29461 tatcttagct gagcaatccg ttttaggggc tatctttatt gatgagagta aacttgtttt
    29521 tgtgcgagaa tacattgagt ctcgggactt ttttaagtat gcccatcgtt tgattttcca
    29581 agccatggtc gatttatccg atcgtggtga tgccatagat gcaacaacgg ttcgtactat
    29641 ccttgataat caaggtgatt tacagaatat tggtggcttg tcttacttgg ttgagattgt
    29701 taattctgtg ccaacttctg ctaatgcgga gtattatgct aagattgttg cagaaaaagc
    29761 aatgctacgt cgtttaattg ccaagttgac agagtctgtc aaccaagctt acgaagcgtc
    29821 acaaccagct gatgaaatta ttgctcaggc agaaaaaggg ctgattgatg tcagtgaaaa
    29881 tgcaaatcga agcgggttta agaacattcg agatgtgttg aatctcaact ttggaaatct
    29941 ggaagctcgc tcgcaacaaa cgaccgatat tacaggtatt gcgacaggtt atcgtgattt
    30001 ggatcatatg acaacaggac ttcatgagga ggagttgatt atcttagcag ctcgtccagc
    30061 agttggtaag acagcatttg ccttgaatat cgctcagaac attgggacta agttggacaa
    30121 aacggttgct attttttcac tcgaaatggg tgcggaaagc ttggtagatc gtatgttagc
    30181 tgcagaaggc ttagtggagt cacattctat ccgtacaggg caattgacag atgaggagtg
    30241 gcaaaaatat actattgctc agggtaatct agctaacgcc agtatctata tcgatgatac
    30301 gccaggtatt cggattacag agattcgttc tcgttctcgt aaattggctc aagaaactgg
    30361 aaatcttggt ttgattttga tagactattt gcaacttatc acgggaactg gtcgagaaaa
    30421 tcgtcaacaa gaagtttctg aaatttctcg tcagttgaaa atactagcca aggaattgaa
    30481 ggttccagta atcgctctga gtcagctttc tcgtggtgta gaacaacgtc aggacaagag
    30541 accggtcttg tctgatattc gtgaatctgg gtctattgag caggacgctg atatcgtagc
    30601 ttttctctat cgcgatgact actatgaacg tggtggtgaa gaagaggagg gtatcccaaa
    30661 taataaggtg gaagttatta tcgagaaaaa ccgtagtgga gctcgtggaa cagtggaatt
    30721 gattttccaa aaagaataca ataaattttc aagtatctca aagagggagg cataagatgt
    30781 cagatgcatt tacagatgta gccaagatga aaaaaatcaa agaagaaatc aaggcacatg
    30841 agggacaagt cgtagaaatg actttggaga atggtcgtaa gcgccaaaaa aatagattgg
    30901 gtaagctaat tgaagtttat ccatctctat ttattgtgga gtttggggat gtggaaggag
    30961 ataaacaagt taatgtttac gttgaatcct ttacttactc agatattctt acagaaaaga
    31021 atttgattca ttatcttgac taaagtgaga aattttctca ctttttcttt tttctccgaa
    31081 taatttaggt gaaggcaatc atcgctttat attatttttc aaggaggaag aatgaaaatt
    31141 ttaccgttta tagcaagagg aacaagttat tacttgaaga tgtcagttaa aaagcttgtt
    31201 ccttttttag tagtaggatt gatgctagca gctggtgata gtgtctatgc ctattccaga
    31261 ggaaatggat cgattgcgcg tggggatgat tatcctgctt attataaaaa tgggagccag
    31321 gagattgatc agtggcgcat gtattctcgt cagtgtactt cttttgtagc ctttcgtttg
    31381 agtaatgtca atggttttga aattccggca gcttatggaa atgcgaatga atggggacat
    31441 cgtgctcgtc gggaaggtta tcgtgtagat aatacaccga cgattggttc cattacttgg
    31501 tctactgcag gaacttatgg tcatgttgcc tgggtgtcaa atgtaatggg agatcagatt
    31561 gagattgagg aatataacta tggttataca gaatcctata ataaacgagt tataaaagca
    31621 aacacgatga caggatttat tcattttaaa gatttggatg gtggcagtgt tgggaatagt
    31681 caatcctcaa cttcaacagg cggaactcat tattttaaga ccaagtctgc tattaaaact
    31741 gaacccctag ttagtgcaac tgtgattgat tactattatc ctggagagaa ggttcattat
    31801 gatcaaattc tcgaaaaaga cggctacaag tggttgagtt atactgccta taatggaagc
    31861 tatcgttatg ttcaattgga ggctgtgaat aaaaatcctc taggtaattc tgttctttct
    31921 tcaacaggtg gaactcatta ttttaagacc aagtctgcta tcaaaactga acccctagtt
    31981 agcggaactg tgattgatta ctattatcct ggggagaagg ttcattatga tcagatactt
    32041 gaaaaagacg gctacaagtg gttgagttat actgcctata atggaagtcg tcgctatata
    32101 cagctagagg gagtgacttc ttcacaaaat tatcagaatc aatcaggaaa tatctctagc
    32161 tatggatcca ataatagttc aactgtcggt tggaagaaaa taaatggtag ttggtatcat
    32221 ttcaaatcaa atggttctaa atcaacagga tggctgaaag acggttctag ctggtattat
    32281 ttgaaattat ctggtgaaat gcagacagga tggttaaagg agaatggctc gtggtattat
    32341 ctgggtagtt caggggcaat gaaaacaggc tggtaccagg tctctggtaa gtggtattat
    32401 tcttactctt caggcgcctt agctgttaat acgacggtgg atggctacag agtaaacagt
    32461 gatggagaac gagtatagaa aattggagta ggagaaattt cctgctcttt tctgtaagca
    32521 gtttccttga catttttctt attttgcgct atcatatata catataatat atgggagtct
    32581 gtgtacagtc tgagaggaag tgttaaactt cgaccgcacc tgatctgggt aatgccagcg
    32641 gagggaacga tacttagtct aattttgcac cttttccatg tatggtaaag gtttttcttt
    32701 tttttaaaag gaaaacgaga agaggaggtt cttatgaaag caagcattgc cttgcaagtt
    32761 ttacccctag cacaggggat tgatcggata gctgttattg atcaggtcat tgcttatctg
    32821 caaactcaag aagtgacgat ggtagtgaca ccatttgaaa cggtcttgga aggggagttt
    32881 gatgagctta tgcgcattct aaaagaagcg ctggaagtgg cagggcagga ggcagacaat
    32941 gtctttgcca atgtcaaaat aaatgtagga gagattttaa gtattgatga gaaacttgaa
    33001 aagtatactg agacgacaca ttagtctatt gggctttctc ggagtattgt caatctggca
    33061 gttagcaggt tttcttaaac ttctccccaa gtttatcctg ccgacacctc ttgaaattct
    33121 ccagcccttt gttcgtgaca gagaatttct ctggcaccat agctgggcga ccttgagagt
    33181 ggctttactg gggctgattt tgggagtttt gattgcctgt cttatggctg tgctcatgga
    33241 tagtttgact tggctcaatg acctgattta ccctatgatg gtggtcattc agaccattcc
    33301 gaccattgcc atagctccta tcctggtctt gtggctgggt tatgggattt tgcccaagat
    33361 tgtcttgatt atcttaacaa caacctttcc catcatcgtt agtattttgg acggttttag
    33421 gcattgtgac aaggatatgc tgactttgtt tagtctgatg cgagcaaacc cttggcaaat
    33481 cctgtggcat tttaaaatcc cggttagcct gccttacttt tatgcaggtc tgagggtcag
    33541 tgtctcctac gcctttatca caactgtggt atctgagtgg ttgggaggtt ttgaaggtct
    33601 tggtgtttat atgattcagt ctaaaaaact gtttcagtat gataccatgt ttgccattat
    33661 tattctggtg tcgattatca gtcttttggg tatgaagctg gtcgatatca gtgaaaaata
    33721 tgtgattaaa tggaaacgta cttaaaatag agcgtttttg aaaaagaaaa gaggaaatca
    33781 aaatgaagaa aacatggaaa gtgtttttaa cgcttgtaac agctcttgta gctgttgtgc
    33841 ttgtggcctg tggtcaagga actgcttcta aagacaacaa agaggcagaa cttaagaagg
    33901 ttgactttat cctagactgg acaccaaata ccaaccacac agggctttat gttgccaagg
    33961 aaaaaggtta tttcaaagaa gctggagtgg atgttgattt gaaattgcca ccagaagaaa
    34021 gttcttctga cttggttatc aacggaaagg caccatttgc agtgtatttc caagactaca
    34081 tggctaagaa attggaaaaa ggagcaggaa tcactgccgt tgcagctatt gttgaacaca
    34141 atacatcagg aatcatctct cgtaaatctg ataatgtaag cagtccaaaa gacttggttg
    34201 gtaagaaata tgggacatgg aatgacccaa ctgaacttgc tatgttgaaa accttggtag
    34261 aatctcaagg tggagacttt gagaaggttg aaaaagtacc aaataacgac tcaaactcaa
    34321 tcacaccgat tgccaatggc gtctttgata ctgcttggat ttactacggt tgggatggta
    34381 tccttgctaa atctcaaggt gtagatgcta acttcatgta cttgaaagac tatgtcaagg
    34441 agtttgacta ctattcacca gttatcatcg caaacaacga ctatctgaaa gataacaaag
    34501 aagaagctcg caaagtcatc caagccatca aaaaaggcta ccaatatgcc atggaacatc
    34561 cagaagaagc tgcagatatt ctcatcaaga atgcacctga actcaaggaa aaacgtgact
    34621 ttgtcatcga atctcaaaaa tacttgtcaa aagaatacgc aagcgacaag gaaaaatggg
    34681 gtcaatttga cgcagctcgc tggaatgctt tctataaatg ggataaagaa aatggtatcc
    34741 ttaaagaaga cttgacagac aaaggcttca ccaacgaatt tgtgaaataa tgacagaaat
    34801 tagactagag catgtcagtt atgcctatgg tcaggagagg attttagagg atatcaacct
    34861 acaggtgact tcaggcgaag tggtttccat tctaggccca agtggtgttg gaaagaccac
    34921 cctctttaat ctaatcgctg ggattttaga agttcagtca gggagaattg tccttgatgg
    34981 tgaagaaaat cccaaggggc gcgtgagtta tatgttgcaa aaggatctgc tcttggagca
    35041 caagacggtg cttggaaata tcattctgcc cctcttgatt caaaaggtgg ataaggcaga
    35101 agctatttcc cgagcggata aaattcttgc gaccttccag ctgacagctg taagagacaa
    35161 gtatcctcat gaacttagcg gtgggatgcg ccagcgtgta gccttactcc ggacctacct
    35221 ttttgggcac aagctctttc tcttagatga ggcctttagc gccttggatg agatgacaaa
    35281 gatggaactc cacgcttggt atcttgagat tcacaaacag ttgcagctaa caaccctgat
    35341 catcacgcat agtattgagg aggccctcaa tctcagcgac cgtatctata tcttgaaaaa
    35401 tcgccctggg cagattgttt cagaaattaa actagattgg tctgaagatg aggacaagga
    35461 agtccaaaag attgcctaca aacgtcaaat cttggcagaa ttaggcttag ataagtagaa
    35521 aaatagggag ttggtgaaga ttatccttta ccagcgccct ttttctttta aaaatgagaa
    35581 aatttcggta taatagtcaa acaaggtcaa ggtttaaaga gagaggtggg tttgttatga
    35641 gatttaaaaa tacatcggat catattgagg cctacatcaa ggcgatttta gatcaatctg
    35701 gtatcgtgga gttgcaacgg agtcagttgg cagatacctt tcaggttgtt cctagtcaga
    35761 ttaactacgt gatcaagaca cgctttacgg aaagtagagg ctacttggtt gaaagtaagc
    35821 gtggtggcgg aggctacatt cgtataggac ggattgagtt ttctagtcat catgaaatgc
    35881 tccgggagct gctttactcg attggtgagc gagtcagtca agaaatttat gaggatattc
    35941 tccagctttt ggttgagcag gaattgatga ccaagcagga gatgaatttg ctagaatcag
    36001 tagctttgga tcgcgtttta ggagaagaag ctccagttgt tcgagcaaac atgctacgtc
    36061 aggtcataca agaggtagat agaaaaggga agtaagatga actattcaaa agcattgaat
    36121 gaatgtatcg aaagtgccta catggttgct ggacattttg gagctcgtta tctagagtcg
    36181 tggcacttgt tgattgccat gtctaatcac agttatagtg tagcaggggc aactttaaat
    36241 gattatccgt atgagatgga ccgtttagaa gaggtggctt tggaactgac tgaaacggac
    36301 tatagccagg atgaaacctt tatggaattg ccgttctccc gtcgtttgca ggttcttttt
    36361 gatgaagcag agtatgtagc gtcagtggtc catgctaagg tactagggac agagcacgtc
    36421 ctctatgcga ttttgcatga tggcaatgcc ttggcgactc gtatcttgga gagggctggt
    36481 ttttcttatg aagacaagaa agatcaggtc aagattgctg ctcttcgtcg aaatttagaa
    36541 gaacgggcag gctggactcg tgaagatctc aaggctttac gccaacgcca tcgtactgtg
    36601 gctgacaaac aaaattctat ggccaatatg atgggcatgc cgcagactcc tagtggtggt
    36661 ctcgaggact atacgcatga tttgacagag caagcgcgtt ctggcaagtt agaaccagtc
    36721 atcggtcggg acaaggaaat ctcacgtatg attcaaatct tgagccgtaa gactaagaac
    36781 aaccctgtct tggttgggga tgctggtgtc gggaaaacag ctctggtgct tggtcttgct
    36841 cagcgtattg ccagtggtga tgtgcctgcg gaaatggcta agatgcgcgt gttagaactt
    36901 gatttgatga atgtcgttgc agggacacgc ttccgtggtg actttgaaga acgcatgaat
    36961 aatatcatca aggatattga agaagatggc caagtcatcc tctttatcga tgaactccac
    37021 accatcatgg gttctggtag cgggattgat tcgactctgg atgcggccaa tatcttgaaa
    37081 ccagccttgg cgcgtggagc tttgagaacg gttggtgcca ccactcagga agaatatcaa
    37141 aaacatatcg aaaaagatgc ggctctttct cgtcgtttcg ctaaagtgac gattgaagaa
    37201 ccaagtgtgg cagatagtat gactatttta caaggtttga aggcgactta tgagaaacat
    37261 caccgtgtac aaatcacaga tgaagcggtt gaaacagcgg ttaagatggc tcatcgttat
    37321 ttaaccagtc gtcacttgcc agactctgct atcgacctct tggacgaagc agcagcaaca
    37381 gtgcaaaata aggtaaagta tgtaaaagca gacgattcag atttgagtcc agctgataag
    37441 gccctgatgg atggcaagtg gaaacaggca gcccagctaa tcgcaaaaga agaggaagta
    37501 cctgtctaca aagacttggt gacagagtct gatattttga ccaccttgag tcgcttgtca
    37561 ggaatcccag ttcaaaaact gactcaaacg gatgctaaga agtatctaaa tcttgaagca
    37621 gaactccata aacgtgtcat cggtcaagat caagctgttt caagcattag tcgtgcgatt
    37681 cgccgtaatc agtcaggaat tcgcagtcac aagcgtccga tcggttcctt tatgttccta
    37741 ggacccacag gtgtcggtaa gaccgagttg gccaaggctt tggcagaagt tctctttgat
    37801 gacgaatcag cccttatccg ctttgatatg agtgagtata tggagaaatt cgcagccagc
    37861 cgtctaaatg gagctcctcc aggctatgtg ggttacgaag aaggtggaga gttgacagag
    37921 aaggttcgca ataaacccta ttccgttctc ctctttgatg aggtagagaa ggcccaccca
    37981 gatattttta atgttctctt gcaggttctg gatgacggtg ttttgacaga tagcaaggga
    38041 cgcaaggtcg atttttcaaa taccattatc attatgacat cgaacctagg tgcgactgcc
    38101 cttcgtgatg ataagactgt tggttttggg gctaaggata ttcgttttga ccaggaaaat
    38161 atggaaaaac gcatgtttga agaactgaaa aaagcttata gaccggaatt catcaaccgt
    38221 attgatgaga aggtggtctt ccatagccta tctagtgacc atatgcagga agtggtgaag
    38281 attatggtca agcctttagt ggcaagtttg gctgaaaaag gcattgactt gaaattacaa
    38341 gcttcagctc tgaaattgtt agcaaatcaa ggatatgacc cagagatggg agctcgccca
    38401 cttcgcagaa ccctgcaaac agaagtggag gacaagttgg cagaacttct tcttaaggga
    38461 gatttagtgg caggcagcac acttaagatt ggtgtcaaag caggccagtt aaaatttgat
    38521 attgcataaa agaataaaag tatcagcatc tgaccataag tcacagtgga gtgaaactca
    38581 atgaaaatca aagagcaaac taggcagcta gccgcaggtt gctcaaaaca ctggtttgag
    38641 gttgcagata gagctgacgt ggtttgaaga gattttcgaa gagtatgaaa ctaaaaccta
    38701 tagcttctaa acgatccgtg gttttcacca ttcaacacaa aattcatatg tttattaccc
    38761 tccgtcgtat ttgtcttaga gcgtgtgtag tagaaaaaga gcagtcttat ctgaaatttt
    38821 tattctttca aaagagacct gtttcttttt tgcatgtcaa atccgttcta gctggtattt
    38881 gaaaaatcaa actaatattc aatgaaaatc aaagaacaaa ctaggcagct agccacaggt
    38941 tgctcaaaac actgttttga ggttgtagat agagctgacg tagtttgaag agattttcga
    39001 agagtataag ctgcaagatg aatgattttc ttgtattgac gttgttgttg acaaaaagta
    39061 gcggataaat gaaatccatt ccattatcat agatgatagg ctggtaggaa attttcaaat
    39121 agcatacagg aaatagatgt atggagttct ggtagtagaa agggagagag atgaacattt
    39181 tagttgcaga tgacgaggaa atgattagag aaggaattgc agcatttctg acagaagagg
    39241 gttatcatgt cattatggct aaggatggac aagaggtctt ggaaaaattt caagatctcc
    39301 ctatccatct catggtattg gatttaatga tgcctaggaa gagtggtttt gaagtgttaa
    39361 aagaaatcaa tcaaaagcac gatattcctg tcatcgtctt gagtgctctg ggagatgaaa
    39421 ctactcagtc acaggtattt gatctctatg ctgatgatca tgtgacaaaa cctttttctt
    39481 tggtactgct tgtcaagcgt attaaggcgc ttatcagacg ttactacgtc atagaggata
    39541 tttggcgata tcaggatgta acagtggatt ttacctctta caaagcacat tataaaaatg
    39601 aagaaattga tctcaaacca aaggaattac tggtactaaa gtgtttgatt cagcataaaa
    39661 atcaagtttt aagtagagag cagatattgg aagaaatttc aaaagatgta gctgatttac
    39721 cttgtgatag ggtcgttgat gtctatattc gtactcttcg caaaaaatta gctttagatt
    39781 gtatcgtgac tgtgaaaaat gttgggtata agattagctt atgataaaaa atcctaaatt
    39841 attaaccaag tcttttttaa gaagttttgc aattctaggt ggtgttggtc tagtcattca
    39901 tatagctatt tatttgacct ttccttttta ttatattcaa ctggaggggg aaaagtttaa
    39961 tgagagcgca agagtgttta cggagtattt aaagactaag acatctgatg aaattccaag
    40021 cttactccag tcttattcaa agtccttgac catatctgct caccttaaaa gagatattgt
    40081 agataagcga ctccctcttg tgcatgactt ggatattaaa gatggaaagc tatcaaatta
    40141 tatcgtgatg ttagatatgt ctgttagtac agcagatggt aaacaggtaa cagtgcaatt
    40201 tgttcacggg gtggatgtct acaaagaagc aaagaatatt ttgtttttgt atcttccata
    40261 tacatttttg gttacaattg ctttttcctt tgttttttct tatttttata ctaaacgctt
    40321 gctcaatcct cttttttaca tttcagaagt gactagtaaa atgcaagatt tggatgacaa
    40381 tattcgtttt gatgaaagta ggaaagatga agttggtgaa gttggagaag ttggaaaaca
    40441 gattaatggt atgtatgagc acttgttgaa ggttattcat gagttggaaa gtcgtaatga
    40501 gcaaattgta aaattgcaaa atcaaaaggt ttcctttgtc cgtggagcat cacatgagtt
    40561 gaaaacccct ttagccagtc ttagaattat cctagagaat atgcagcata atattggaga
    40621 ttacaaagat catccaaaat atattgcaaa gagtataaat aagattgacc agatgagcca
    40681 cttattggaa gaagtactgg agtcttctaa attccaagag tggacagagt gtcgtgagac
    40741 cttgactgtt aagccagttt tagtagatat tttatcacgt tatcaagaat tagctcattc
    40801 aataggtgtt acaattgaaa atcaattgac agatgctacc agggtcgtca tgagtcttag
    40861 ggcattggat aaggttttga caaacctgat tagtaatgca attaaatatt cagataaaaa
    40921 tgggcgcgta atcatatccg agcaagatgg ctatctctct atcaaaaata catgtgcgcc
    40981 tctaagtgac caagaactag aacatttatt tgatatattc tatcattctc aaatcgtgac
    41041 agataaggat gaaagttccg gtttgggtct ttacattgtg aataatattt tagaaagcta
    41101 tcaaatggac tatagttttc tcccttatga acacggtatg gaatttaaga ttagcttgta
    41161 gacagattag ttttttatta aagttcatat agggttaaca taagtgtgtt attctttgtg
    41221 tagataaaag aaaggatact aatatggtat tagcgattat tttagtaaca ttctttattc
    41281 gattgatttt tttaaagcgt tcgatagaga atgagaaacg aatccttagc aatggcggga
    41341 aagaatttgg agttgagaat acaaaacgat taactatggc tcatattgtt ttttatctct
    41401 cttgcttggt tgaggcaatg gtgcacaaga caatttttga tggcatgggc atggttggtt
    41461 tagtcttgct tattttttct atgctgatgt taatgttggt gattcacttg ttgggagata
    41521 tttggacagt gaagcttatg cttgtcaata atcacaaata tgtagatcat atcttgttta
    41581 ggacagtaaa acatcctaat tactttttaa atattcttcc tgagttgatt ggcttgacct
    41641 tgttgagtca tgcttatgtg acttttgttt tagtttttcc agtttatgca gttattttgt
    41701 atcgacgaat agctgaagag gaaaagctat tacatgaagt tataatccca aatggaagca
    41761 taaagagata aatacaaaat tcgatttata tacagttcat attgaagtga tatagtaagg
    41821 ttaaagaaaa aatatagaag gaaataaaca tgtttgcatc aaaaagcgaa agaaaagtac
    41881 attattcaat tcgtaaattt agtattggag tagctagtgt agtagttgct agcttgttct
    41941 taggaggagt agttcatgca gaaggggtta gaagtgggga tacccccaag gttacatcta
    42001 gtggggatga agtcgagtcg catctaaaaa aaatattgag tgagatccaa acacaattag
    42061 atagaaaacg acatgccaaa actgtagcgc taattaacaa gttgcaagac attaagagaa
    42121 cgtattcgta taaattaaat gttttagaag agaagccgaa agctgagttg acgtcaaaaa
    42181 caaaagaaga gttaaccgca gcttttgagc aatttaaaaa agatacatta ccaacagaac
    42241 caggaaaaaa ggtagcagaa gctgagaaga aggttgcaga agctgagaaa aaagccgagg
    42301 atcaaaaaga agaagatcgt cgtaactacc caaccaatac ttacaaaacg cttgaacttg
    42361 aaattgctga gttcgatgtg aaagttaaag aagcggagct tgaactatta aaagagaaag
    42421 ctaagaaacc tttaaacgag ggcacaatta agcaagcaaa agagaaagtt gagagtaaaa
    42481 aagctgaggc tacaaggtta gaaaacatca agacagatcg taaaaaagca gaagaagaag
    42541 ctaaacgaaa agcagcagaa gaagataaag ttaaagaaaa accagctgaa caaccacaac
    42601 cagcgccggc tcctcaacca gaaaaaccag ctccaaaacc agaaaaacca gctccagctc
    42661 caaaaccaga gaatccagct gaacaaccaa aagcagaaaa accagctgat caacaagctg
    42721 aagaagacta tgctcgtaga tcagaagaag aatataatcg cttgactcaa cagcaaccgc
    42781 caaaaactga aaaaccagca caaccatcta ctccaaaaac aggctggaaa caagaaaacg
    42841 gtatgtggta cttctacaat actgatggtt caatggcgac aggatggctc caaaacaatg
    42901 gctcatggta ctacctcaac agcaatggcg ctatggcgac aggatggctc caaaacaatg
    42961 gttcatggta ctatctaaac gctaatggtt caatggcaac aggatggctc caaaacaatg
    43021 g
//
LOCUS       DAVBIC010000012        42741 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.012, whole genome shotgun sequence.
ACCESSION   DAVBIC010000012 DAVBIC010000000
VERSION     DAVBIC010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 42741)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42741)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42741
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.012"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            1..366
                     /locus_tag="VQ664_000616"
                     /pseudo
     CDS             1..366
                     /locus_tag="VQ664_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(411..1052)
                     /gene="plsY"
                     /locus_tag="VQ664_000617"
     CDS             complement(411..1052)
                     /gene="plsY"
                     /locus_tag="VQ664_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HET2788831.1"
                     /translation="MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
     gene            1188..3131
                     /gene="parE"
                     /locus_tag="VQ664_000618"
     CDS             1188..3131
                     /gene="parE"
                     /locus_tag="VQ664_000618"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HET2788832.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KIGTAPKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGLKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVINTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            3551..6022
                     /gene="parC"
                     /locus_tag="VQ664_000619"
     CDS             3551..6022
                     /gene="parC"
                     /locus_tag="VQ664_000619"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HET2788833.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKNTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLA
                     AIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEEILYVEVLDQFDDATTYFAVTRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            6154..7176
                     /locus_tag="VQ664_000620"
     CDS             6154..7176
                     /locus_tag="VQ664_000620"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HET2788834.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGTGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            7232..7936
                     /locus_tag="VQ664_000621"
     CDS             7232..7936
                     /locus_tag="VQ664_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2788835.1"
                     /translation="MVLSTSAILVACGKTDKEADAPTTFSYVYAVDPASLGYSIATRT
                     SRTDVIGNVIDGLMENDKYGNVAPSQKDYDLNSTGWAPSYQDPASYLNIMDPKSGSDM
                     KHLGITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMP
                     TASSGGFPVVSNVVPFSKPYSQVGIKGEPYIFKGMKLQKDIVTTKEYNEVFKKWQKEK
                     LESNSKYQKELEKYIK"
     gene            8001..8690
                     /locus_tag="VQ664_000622"
     CDS             8001..8690
                     /locus_tag="VQ664_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HET2788836.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            8687..9610
                     /locus_tag="VQ664_000623"
     CDS             8687..9610
                     /locus_tag="VQ664_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HET2788837.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            9625..10269
                     /gene="pcp"
                     /locus_tag="VQ664_000624"
     CDS             9625..10269
                     /gene="pcp"
                     /locus_tag="VQ664_000624"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HET2788838.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            10437..10667
                     /locus_tag="VQ664_000625"
     CDS             10437..10667
                     /locus_tag="VQ664_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HET2788839.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            10717..10797
                     /locus_tag="VQ664_000626"
     tRNA            10717..10797
                     /locus_tag="VQ664_000626"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10751..10753,aa:Tyr,seq:gta)
     gene            10807..10878
                     /locus_tag="VQ664_000627"
     tRNA            10807..10878
                     /locus_tag="VQ664_000627"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10839..10841,aa:Gln,seq:ttg)
     gene            11040..12242
                     /gene="rpsA"
                     /locus_tag="VQ664_000628"
     CDS             11040..12242
                     /gene="rpsA"
                     /locus_tag="VQ664_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HET2788840.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFIDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRAARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
     gene            12328..12825
                     /locus_tag="VQ664_000629"
     CDS             12328..12825
                     /locus_tag="VQ664_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HET2788841.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTTWDFTM
                     FEEKS"
     gene            12825..14480
                     /gene="dnaX"
                     /locus_tag="VQ664_000630"
     CDS             12825..14480
                     /gene="dnaX"
                     /locus_tag="VQ664_000630"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HET2788842.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVSLADIK
                     SSLQPKIYAEMMTVRLAEIKPEPALSGAVENEIATLRQEVARLKQELSNVGAVPKQVA
                     PAPSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLVGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            14508..14702
                     /locus_tag="VQ664_000631"
     CDS             14508..14702
                     /locus_tag="VQ664_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HET2788843.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            14852..15622
                     /gene="sufC"
                     /locus_tag="VQ664_000632"
     CDS             14852..15622
                     /gene="sufC"
                     /locus_tag="VQ664_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HET2788844.1"
                     /translation="MSVLEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEDDEKISVREFITRLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            15650..16912
                     /gene="sufD"
                     /locus_tag="VQ664_000633"
     CDS             15650..16912
                     /gene="sufD"
                     /locus_tag="VQ664_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HET2788845.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKINYLERLESRGEGSAKATANITVEVIARSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLIGNGSYADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            16923..18149
                     /locus_tag="VQ664_000634"
     CDS             16923..18149
                     /locus_tag="VQ664_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HET2788846.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     FAEEILTEGDQVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVVNPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQSASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAVEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVPASARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            18136..18576
                     /locus_tag="VQ664_000635"
     CDS             18136..18576
                     /locus_tag="VQ664_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HET2788847.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQISLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDAVLGKTKQEILELATIFSEMVQGQ
                     KDERQDQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            18626..20038
                     /gene="sufB"
                     /locus_tag="VQ664_000636"
     CDS             18626..20038
                     /gene="sufB"
                     /locus_tag="VQ664_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HET2788848.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(20269..21510)
                     /locus_tag="VQ664_000637"
     CDS             complement(20269..21510)
                     /locus_tag="VQ664_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HET2788849.1"
                     /translation="MKKIFLTLLTVSLLGGASTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITAYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFIDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKAPVQDGKEDTVTAVAPEDIYLIERV
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKDLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            21613..22722
                     /locus_tag="VQ664_000638"
     CDS             21613..22722
                     /locus_tag="VQ664_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HET2788850.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
     gene            23256..23603
                     /gene="ssrA"
                     /locus_tag="VQ664_000639"
     tmRNA           23256..23603
                     /gene="ssrA"
                     /locus_tag="VQ664_000639"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(23786..23873)
                     /locus_tag="VQ664_000640"
     tRNA            complement(23786..23873)
                     /locus_tag="VQ664_000640"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(23837..23839),aa:Ser,seq:gga)
     gene            24035..24775
                     /locus_tag="VQ664_000641"
     CDS             24035..24775
                     /locus_tag="VQ664_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET2788851.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNITVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            24772..25683
                     /gene="pfkB"
                     /locus_tag="VQ664_000642"
     CDS             24772..25683
                     /gene="pfkB"
                     /locus_tag="VQ664_000642"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HET2788852.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVESVQLEELKAILSSLTAEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSEGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDVVEAFKWGVACG
                     TATTFSDDLATAEFIKETYGKVEVEKR"
     gene            25680..27632
                     /locus_tag="VQ664_000643"
     CDS             25680..27632
                     /locus_tag="VQ664_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET2788853.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTDHGYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSADQVIELFDQASEKTEELVQAP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAK
                     AATASNEKQSLGGALYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALGVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            27796..30021
                     /locus_tag="VQ664_000644"
     CDS             27796..30021
                     /locus_tag="VQ664_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HET2788854.1"
                     /translation="MLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGSLAYLAIFGL
                     LIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGTMAQVVTDLT
                     GFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWSVYDIAEFFS
                     RGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPPVDMETGEIL
                     TEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDEDVQVDFSAKEALEYKLPS
                     LQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFRELWEQSQTK
                     AENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASILMKARPDQV
                     KFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFAKVGVRNI
                     AGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVNFIKTQADADYDESFDPGEVSENEGEFSDGDAGGD
                     PLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEIAGVIGPAEGTKPRKVLQ
                     Q"
     gene            complement(30066..30494)
                     /locus_tag="VQ664_000645"
     CDS             complement(30066..30494)
                     /locus_tag="VQ664_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2788855.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTVATIASILGLITASITIMN
                     ALDNNKNIKKEPTTSQTTTIVKEIQKESPKENTSPTKETNTSQEKTQQEETPKSSVKE
                     EKKEDQKTATQDSSTPASSKPATENEKQSNAPTSENKSNQ"
     gene            30632..31774
                     /locus_tag="VQ664_000646"
     CDS             30632..31774
                     /locus_tag="VQ664_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HET2788856.1"
                     /translation="MIYFDNSATTKPYPEALETYMQVASKILGNPSSLHRLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWLIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKSQGFEVDFAPVDKKGLVDVEALAGLIRHDTILVSIMAVNNEIGSIQPIEAI
                     SEFLADKPTISFHVDAVQALAKIPTEKYLTERVDCATFSSHKFHGVRGVGFVYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIRQALL
                     NYPDIFVFSDEENFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAKSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            31783..32997
                     /gene="thiI"
                     /locus_tag="VQ664_000647"
     CDS             31783..32997
                     /gene="thiI"
                     /locus_tag="VQ664_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HET2788857.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYTQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSSVQEIMRDIYKE
                     GMTFKISSKRSDHNFELDSRELNQTLGGAVFEAIPNVQVQMKSPDINLQVEIREEAAY
                     LSYETIRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            33132..33956
                     /locus_tag="VQ664_000648"
     CDS             33132..33956
                     /locus_tag="VQ664_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET2788858.1"
                     /translation="MNQSYFYLKMKEHKLKVPYTGKERRVRILLPKDYEKDTDRSYPV
                     VYFHDGQNVFNSKESFIGHSWKIIPAIKRNPDISRMIVVAIDNDGMGRMNEYAAWKFQ
                     ESPIPGQQFGGKGVEYAEFVMEVVKPFIDETYRTKADCQHTAMIGSSLGGNITQFIGL
                     EYQDQIGCLGVFSSANWLHQEAFNRYFECQKLSPDQRIFIYVGTEEADDTDKTLMDGN
                     IKQAYIDSSLCYYHDLIAGGVHLDNLVLKVQSGAIHSEIPWSENLPDCLRFFAEKW"
     gene            33978..34717
                     /locus_tag="VQ664_000649"
                     /pseudo
     CDS             33978..34717
                     /locus_tag="VQ664_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546805.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
     gene            34730..35896
                     /locus_tag="VQ664_000650"
     CDS             34730..35896
                     /locus_tag="VQ664_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HET2788859.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPIGRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGA
                     AATFKLETEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYA
                     YTPLDLMIYKMDNSYYVLKDMDPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYITIE
                     YNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGEEFPASDFETQYCLATSRRANAHYVY
                     SEEDLLAKYSQQFKVKKVMPAAFAELQGDYLYMLTTPSRQEMEQMIADFGQRQE"
     gene            36404..37897
                     /locus_tag="VQ664_000651"
     CDS             36404..37897
                     /locus_tag="VQ664_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HET2788860.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDKV
                     WFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            37910..38956
                     /locus_tag="VQ664_000652"
     CDS             37910..38956
                     /locus_tag="VQ664_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET2788861.1"
                     /translation="MKKVKLGEVLSLKKGKKATVLAEQTTLSQRYIQIDDLRNNNNLK
                     FTESLNMTEALPDDILIAWDGANAGTVGYGLSGAVGSTITVLKKNERYKEKIISDYLG
                     VFLESKSQYLREHSTGATIPHLNKNILLDLQLELLGIEEQENIICILNTIKRLITKRK
                     LQLDELNLLVKSRFNEMFGDVILNEKEWKVSKWNEILTIRNGKNQKQVEDADGKFPIY
                     GSGGIMGYAKDWIVKKNSVIIGRKGNINKPILVRENFWNVDTAFGLEPVLEKINSEYL
                     FYFCQLYNFEKLNKAVTIPSLTKSDLLNISIPLPPLALQNEFADFVALVDKSQFACEI
                     AIKVWRNSLKFSII"
     gene            38986..41682
                     /locus_tag="VQ664_000653"
                     /pseudo
     CDS             38986..41682
                     /locus_tag="VQ664_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
     gene            complement(41716..>42741)
                     /locus_tag="VQ664_000654"
     CDS             complement(41716..>42741)
                     /locus_tag="VQ664_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element IS1167A family transposase"
                     /protein_id="HET2788862.1"
                     /translation="RRFKCYHCSKMMVAETPLVKKNHQIPRIINQKIAQKLIEKISMT
                     DIAHQLAISTSTVIRKLNDFHFEHDFSRLPKIMSWDEYAFTKGKMSFIAQDFDNLNII
                     TVLEGRTQAVIRNHFLRYDRAVRCQVKIITMDMFSPYYDLAKQLFPCAKIVLDRFHII
                     QHLSRAMSRFRVQIMNQFERKSHEYKAIKRYWKLIQQDSRKLSDKRFYRPTFRMHLTN
                     KEILDKILSYSEDLKHHYQIYQLLLFHFQNKDPEKFFGLIEDNLKQVHPLFQTVFKTF
                     LKNKEKIVNALQLHYSNAKLEATNNLIKLIKRNAFGFRNFENFKKRIFIALNIKKERT
                     KFVLSQA"
BASE COUNT        12969 a         7666 c         9466 g        12640 t
ORIGIN      
        1 cccaacttag aacaagtata aacaatgttg gaacaggcat tcaaagagaa gcactacgag
       61 aatacgattc tccatagtga ccaaggctgg caatatcaac acgattctta tcatcagttc
      121 ctagagagta agggaattca agcatccatg tcacgtaagg gaaacagccc agacaatggt
      181 atgatggagt ccttctttgg gattctgaaa tcggaaatgt tttacggtta tgagaagtcg
      241 tttcagtcgc ttaagcaatt ggaacaagcc attatagact atattgatta ctacaacaat
      301 aaacgaatta agataaaact aaaaggactt agccctgtgc aatacagaac taaatccttc
      361 ggataaatta attgtctaac ttttggggtg cagttcacag aactggcatt ttatttttta
      421 ggatcttgat gggttaggtt caatccccaa gggaccaaat tttcagtttt atttttgata
      481 cgagctatat tgtccttatg acgaatgata atcaaactag caagtgctaa gataatagcg
      541 atgaagagag agtcatagtt actcaggata aaaccaaaaa gtggaaagag cagaaccccg
      601 ataacagccg cgatcgatgc tgtgacacta gacagtgaaa tcatactgcc aagatagaga
      661 gctccaaaga agataatcgc aaggtagaga cagaagatag gcgcaaatcc gaaaattact
      721 ccagcactgg ttgcgacagc cttaccacct ttaaatcctg caaagatagg gaaggtatgg
      781 ccgataacag ccaaaagtcc aaagatgaga ggagaaacgc cttgtagatg aaaaataatc
      841 ggaagcagcg ttgctagggt tcctttgaaa aagtcaatca caaaggttgc cataccagct
      901 ttcttaccta aaatgcggaa ggtattggtc gttccagtgt taccagaacc atgctcgcgt
      961 agattgattt gaaagaatac ttgtccaatc cagagaccag atggaatcga acccagcaga
     1021 taggctagga ttaataaaac tattgtaatc atactcctat tatatcatga attgggaaag
     1081 aaaagcagag aatctctgct aaaattgtca catcggagaa agaaaaattt tgcaaaatcc
     1141 ttggaaaacc tgtagaatag taaagatgaa cgaataggag gttccttgtg tcaaaaaagg
     1201 aaatcaatat taacaattat aatgatgatg ctattcaggt gctagaaggg ttggatgcgg
     1261 tccgaaaacg tccagggatg tatattggat cgaccgatgg cgctggtctt catcacctag
     1321 tttgggaaat cgttgataat gcagtcgatg aagccttgtc tgggtttggt gatcgtatcg
     1381 atgtaaccat caataaagac ggtagtctaa cggttcaaga ccatggacgt gggatgccga
     1441 caggtatgca cgctatggga attccaactg ttgaggttat ctttaccatt cttcatgccg
     1501 gagggaaatt cggtcaaggt ggctataaga catcaggtgg acttcacgga gtgggttctt
     1561 ccgttgttaa cgccctttct agctggttag aagttgaaat tacccgtgat ggcgcagttt
     1621 acaagcaacg tttcgaaaat ggtggaaaac ctgtcacgac tttgaagaaa atcggtacag
     1681 cacccaagtc taaaacaggc accaaagtta cttttatgcc tgacgcgact atattttcta
     1741 cgacagattt caagtacaat accatttcag agcgccttaa tgaatcagcc tttctcttga
     1801 aaaatgtgac cttgtcttta acggacaagc gaacagatga agcgattgag ttccactatg
     1861 agaatggagt acaagatttt gtttcttatc tcaacgaaga taaggaaatc ttgacgccag
     1921 ttctttactt tgaaggggaa gacaatggtt ttcaagtgga agtagccctc cagtacaatg
     1981 acggattctc agataacatt ctatcctttg tcaataacgt tcgcaccaag gacggtggaa
     2041 cgcacgagac aggactcaag tctgccatta ccaaggtcat gaatgactat gcacgtaaaa
     2101 caggtcttct caaggaaaaa gataaaaacc ttgaaggttc agactatcgt gagggactag
     2161 cggccgttct ttctatctta gttcctgaag aacacttgca gtttgaagga cagaccaagg
     2221 ataaactagg aagcccccta gctcgcccag ttgtggatgg aatagtggct gataagttga
     2281 cctttttcct tatggaaaat ggggaattag cttctaacct catccgcaag gctatcaagg
     2341 cccgtgatgc tcgtgaagca gcacgtaagg cgcgtgatga gagccgaaat gggaagaaaa
     2401 acaagaaaga taagggcttg ttgtctggga aattgacccc agcccaatct aagaatcctg
     2461 ctaagaatga actctatcta gttgaggggg actctgccgg tggttctgcc aaacaaggtc
     2521 gtgaccgcaa gttccaggct attctacctc ttcgtggtaa ggttatcaat acagccaagg
     2581 ccaagatggc ggatatcctc aaaaatgaag agatcaatac catgatttat accattggtg
     2641 cgggtgttgg agcagacttc tctattgaag atgccaacta tgataagatc attatcatga
     2701 ccgatgcgga taccgacggt gcccatatcc agaccttgct cttgacattt ttctaccgtt
     2761 acatgcgtcc gctagtcgag gcaggtcatg tctatattgc cctcccacct ctttacaaga
     2821 tgtccaaagg taaaggaaag aaagaagaag tggcctacgc ttggacggac ggagaactag
     2881 aagaactccg taaacagttc ggtaaaggcg ctaccctcca acgatacaaa ggacttggtg
     2941 agatgaatgc ggaccagctc tgggaaacaa ccatgaaccc agaaacacgt accctcatcc
     3001 gtgtcacaat tgaagattta gcgcgcgccg aacgccgcgt caatgttctc atgggagata
     3061 aggtagaacc acgccgtaaa tggattgaag ataatgtcaa gtttacgcta gaagaagcga
     3121 cagtgtttta atgaaagaaa ataatatgtt agtaaactgg aaattagagt cggatgtgaa
     3181 tgactatgtg aaaaagcagt ttgaaaatct tggtttgaaa aaattgcagg attattaatg
     3241 aagaatctgc tatgagtgct tatctcaaag aggcgcttaa gggagcggct aagacacaaa
     3301 ctaagactaa ttttggaaaa ccagattttc atattgaaaa atacaaacag gatagtttgg
     3361 ttacttatcg taactgaaca cgggaggaat tcccgtaaaa tatcttttac tgcataaaaa
     3421 cctactctac attctttgaa aggagttgaa cacgccctag atactgtgtg aaaaagataa
     3481 attctcttgt gagtttgctt acttcaagaa ttttctattt tcacttggta ttttatgggc
     3541 tttgtatctt atgtctaaca ttcaaaacat gtccctggag gacatcatgg gagagcgctt
     3601 tggtcgctac tccaagtaca ttattcaaga ccgggctttg ccagatattc gtgatgggtt
     3661 gaagccggtt cagcgccgta ttctttattc tatgaataag gatagcaata cttttgacaa
     3721 gagctaccgt aagtcggcca agtcagtcgg gaacatcatg gggaatttcc acccacacgg
     3781 ggattcttct atctatgatg ccatggttcg tatgtcacag aactggaaaa atcgtgagat
     3841 tctagttgaa atgcacggta ataacggttc tatggacgga gatcctcctg cggctatgcg
     3901 ttatactgag gcacgtttgt ctgaaattgc aggttacctt cttcaggata tcgagaaaaa
     3961 tacagttcct tttgcatgga actttgacga tacggagaaa gaaccaacgg tcttgccagc
     4021 agcctttcca aacctcttgg tcaatggttc gactgggatt tcggctggtt atgccacaga
     4081 cattcctccc cataatttag ctgaggtcat agatgctgca gtttacatga ttgaccaccc
     4141 aactgcaaag attgataaac tcatggaatt cttgcctgga ccagacttcc ctacaggggc
     4201 tattattcag ggtcgtgatg aaatcaagaa agcttatgag actgggaaag ggcgcgtggt
     4261 tgttcgttcc aagactgaaa ttgaaaagct aaaaggtggt aaggaacaaa tcgttattac
     4321 tgagattcct tatgaaatca ataaggccaa tctagtcaag aaaatcgatg atgttcgtgt
     4381 taataacaag gtagctggga ttgctgaggt tcgtgatgag tctgaccgtg atggtcttcg
     4441 tatcgctatc gaacttaaga aagacgctaa tactgagctt gttctcaact acttatttaa
     4501 gtacaccgac ctacaaatca actacaactt taatatggtg gcgattgaca atttcacacc
     4561 tcgtcaggtt gggattgttc caatcctgtc tagctacatc gctcaccgtc gagaagtgat
     4621 tttggcgcgt tcacgctttg acaaagaaaa ggctgagaaa cgtctccata tcgtcgaagg
     4681 tttgattcgt gtgatttcga ttttggatga agtcattgct cttatccgtg cttctgagaa
     4741 taaggcggac gccaaggaaa acctcaaagt tagctatgat tttacggaag aacaggctga
     4801 ggctatcgta actttgcaac tgtaccgttt gaccaatacc gatgtggttg tcttgcagga
     4861 agaagaagca gagcttcgtg agaagattgc tatgctggcg gctattatcg gtgatgaaag
     4921 gactatgtac aatctcatga agaaagaact tcgtgaggtc aagaagaaat ttgcaactcc
     4981 tcgtttgagt tctttagaag acactgcgaa agcaattgag attgatacag ctagtcttat
     5041 cgctgaggaa gatacctacg tcagcgtgac caaggcaggt tacatcaagc gtaccagtcc
     5101 acgttccttt gcggcttcca ccttggaaga aattggcaag cgtgatgatg accgtttgat
     5161 ttttgttcaa tctgccaaga caacccagca cctcttgatg ttcacaagtc ttggaaatgt
     5221 catctacaga ccaatccatg agttggcaga tattcgttgg aaggacatcg gagagcatct
     5281 gagccaaacc atcacaaact ttgaaacgaa tgaagaaatc ctttatgtgg aagtactgga
     5341 tcagtttgac gatgcgacaa cctactttgc agtgactcgc cttggtcaaa tcaaacgggt
     5401 agagcgaaaa gaattcactc catggcggac ctatagatct aagtctgtca agtatgctaa
     5461 gctcaaagac gatacagatc agattgtagc agtggctccg attaaactag atgatgttgt
     5521 cttggttagt caaaatggtt atgccctgcg tttcaatatc gaagaggttc cggttgtcgg
     5581 tgctaaggca gcaggtgtca aggctatgaa tttgaaagaa gatgatgtcc tccaatctgg
     5641 ctttatctgt aatacttcgt ccttctacct cttgacccag cgtggaagct tgaaacgtgt
     5701 ttctattgag gaaattctag caaccagccg tgccaaacga ggattacaag tcttgcgtga
     5761 gttgaaaaac aaaccgcatc gtgtcttctt ggcaggagca gttgcagagc aaggatttgt
     5821 tggcgatttc ttcagtacgg aagtggatgt gaacgaccaa actctgcttg tccaatccaa
     5881 taaaggaaca atctatgaaa gccgattgca agacttgaac ttgtcagaac gcactagcaa
     5941 tggaagcttc atttctgaca cgatttcaga tgaagaagtt tttgacgctt atcttcagga
     6001 agtagttact gaagataaat aagtgaaatg aagaatcagt tctaagagct ggtttttatt
     6061 ggagaaattt tctgaaaatt acaaaatata cttgctattt tagaaaaata gtgtagaata
     6121 taagaaatag gtttttagaa taaggagtgg aatatgacag taacgattga ttgggaaaac
     6181 ctcggttttt cctatatgaa attaccttat cgctatcttg ctcatttcaa aaatggacaa
     6241 tgggatcaag gagagcttac agaggatgca actttgcata tttcagagtc ttctccaagt
     6301 cttcactatg gacaacaagc atttgaaggt ttgaaagctt atcgtactaa ggatggcagt
     6361 gttcaactgt tccgtcctga tgaaaatgct aaacgtctgc aacgtacatg tgaccgtctc
     6421 ttgatgccac aagttccgac agacatgttt gtagaagctt gtaaagcagt tgtccgtgcg
     6481 aatgaagaat acgtaccacc atacggaaca ggtggaacct tatatcttcg ccctcttttg
     6541 attggtgtcg gagatattat cggggtaaaa ccggcagaag agtacatttt caccatcttt
     6601 gctatgccag ttggaaatta ctttaaaggt ggtttggtcc caaccaactt cttgattcag
     6661 gatgagtacg accgtgcagc accaaatggt acaggtgcgg ctaaggttgg tggaaactat
     6721 gctgcaagtc tcttaccagg aaaaatggcc aagtcacgtc atttctcaga tgttatctat
     6781 ctggacccat caactcatac aaagattgaa gaagtcggat cagctaactt ctttggaatt
     6841 acagctgata atgaatttgt aacaccattg agtccatcta tcttgccatc tattaccaag
     6901 tattccttgc tttatttggc agaacatcgc ttgggattaa ctcctattga gggtgatgtt
     6961 ccaattgata atcttgaccg ttttgtagag gcaggtgcct gtggtacagc agcggttatt
     7021 tctccaattg gaggtattca acatggtgat gatttccatg tattctatag tgaaacagaa
     7081 gtaggtcctg tgacgcgtaa attatataat gaattgacgg gtattcagtt tggcgatatt
     7141 gaagcgccag aaggttggat tgtaaaagta gattaaaata aaccaaagga gattttttat
     7201 gaaatagaaa aagtggctct taacagcagg agtggtcctg agcacgtcag ctattttagt
     7261 ggcttgtgga aaaactgata aagaagcaga tgcaccgaca acattttctt atgtctatgc
     7321 agtagatcca gcatcattgg gctacagtat agcgactcga acatcgagga cagacgttat
     7381 tggaaatgtt attgatggtt tgatggaaaa tgataaatac ggcaatgttg ctccttctca
     7441 aaaagactat gatttgaaca gtacaggatg ggctccaagc tatcaagatc cagcgtctta
     7501 cttgaatatt atggatccaa aatctggttc tgacatgaaa caccttggca ttacgaaagg
     7561 aaaagataag gatgttgtag ctaaacctgg tttggataaa tataagaaat tgttagaaga
     7621 tgctgtttct gagaccactg acctagagaa gagatatgaa aaatatgcca aagctcaagc
     7681 ttggtcgaca gatagttcat tattgatgcc aacagcttca tctggtggtt ttccagttgt
     7741 aagtaacgta gtaccattct caaaaccata ctcacaagtt ggtattaagg gggaaccata
     7801 tatctttaaa ggaatgaaat tgcaaaaaga tattgttaca acaaaagaat ataacgaggt
     7861 ttttaaaaaa tggcaaaaag aaaaattgga atccaatagc aaataccaaa aagaactaga
     7921 aaaatacatt aaataaggaa tggtattgat cttgataaaa tttttaaaat actgtcattt
     7981 tgaatataaa ggagtttgat atggagtgga ttagattaat aggaatagca atcattgttg
     8041 tgggttttat tttaaaattt gatacaattg caacagtagt cttagctggt ttggttacag
     8101 ctttagtttc aggtgtttct ctcgttgaat ttttggagat tttgggaaaa gaatttagca
     8161 atcagcgagt gctcacgatt tttatggtta ccttgcctct tgtggggctg tcagaaacct
     8221 ttggactcaa gcaacgatca atcgatttga ttcgaaagat taaaggtctg acagttggaa
     8281 acttctatac agtttatttc tttattcgag agttagctgg tttcttttca attcgtctag
     8341 gaggacaccc tcagtttgtc agacctttgg ttcaacctat gggagaagca gctgcagagt
     8401 ctcaattagg tagaaagtta acagaggttg aagatgagac aataaaagcg cgtgcggctg
     8461 cgaatgaaaa ttttggaaat ttctttgctc aaaatacgtt tgtaggtgct gggggagtcc
     8521 tcttgatagg gggaacatta gatcagttag gctatgaaag caattatgca gggattgctt
     8581 ctacatctat tattgttgct gttataacac ttattgtagt ggggatttac aattatttat
     8641 ttgataaaaa attgatatca aaaaagacta ggggaggaga acaaaaatga cagagttggc
     8701 aaagcaacta ttagagttga cctatattgt gattggttgt caatttctcc atacagccta
     8761 ttgtagttat aaagataaaa caaacccagt tcgacttggg acatctgcat tttggactct
     8821 attgtctatt acgtttatag gtggttccta tatgccaaat atgagtattg gtattattgt
     8881 aatcctatta tcgctgttaa cattgtttaa gcaagtccgt atcggaacct tgccatcctt
     8941 agatgaaatg aaagccaata ttgaatctaa caggttgaaa aataaaattt ttattccagt
     9001 tatgctgatg gcaatacttg cgttggtctt agcgcaaatg attccagaat ttagcaagat
     9061 ttcgattagc cttgccgcct tgtttgctac aatttctgtt cttgtgatta ccaatagtca
     9121 ccctaagagt ctgttatcag aaaataatcg aatgactcag caagtttcaa caagtgggat
     9181 tgttcctcaa ttattagggg ctttgggggc tatttttact gtagcaggtg ttggtgatgt
     9241 tatctctcat ctgattagcg gtattgttcc ttcagatagt cgctttatag gagttttggc
     9301 ttatgttctt ggaatggttc tattcacaat gattatggga aatgcttttg cagcattcac
     9361 cgttattaca gcaggtgttg gagttccctt tgtatttgct ctgggagcta atccaattgt
     9421 ggctggtgct cttgccatga cagcaggtta ttgtgggacc ttattgaccc caatggctgc
     9481 taattttaac gctctaccag cagcattgat ggatatgaaa gatcagaatg gcgttataaa
     9541 ggctcaagca ggtgttgctc tagtaatgat tgttattcac atattcttaa tgtactttct
     9601 cgcattttag taaaggaaaa taaaatgaaa atattggtta caggttttaa tccttttgga
     9661 ggtgaaaaga ttaatccagc tttggaggct gtaaaattat taccatctga gattaatggg
     9721 gctgaagttc gctgggtaga aattccaacg gttttttata agtcgtcaga agttttagag
     9781 gcagaaatat tacgatatca accagatgct gtactttgta ttggacaagc aggcggcagg
     9841 accggcttaa cacctgaacg agtggctatt aatcaagatg atgctcgcat acctgataac
     9901 gaaggcaatc aaccaattga tacaccgatt cgtattgatg gagcatcggc ctattttagt
     9961 agtttaccta tcaaagcgat ggtacaagct atcaaaaaac agggacttcc ggcagttgta
    10021 tccaatagtg caggaacctt tgtttgcaat catttgatgt accaagctct ttatttagtg
    10081 gataaaaaat tccctaatat gagagcaggt ttcatgcata ttccatatat gatggaacaa
    10141 gtagtaaata agccgaatac tgcaggaatg agtctatgtg atattgtaag aggcatagag
    10201 gtagctattg aagctattgt agactacaaa gataaggatt tgcagttagt aggcggtgag
    10261 actcactgat aacctaaaaa ggatagtcaa ttatgcttgt ttactaacta ttaactatgc
    10321 taaatcaatt gaggttgttt acataaaact ctatatcaga gaagcctgat atagagtttt
    10381 ttcttgctag ttttaggatt ttcttgtaaa atagaaaaag tgaagagagg tatgaaatga
    10441 gcaagaaaga taaaaaaatc gaaattcaag tagcggatgc caaagttaat gttggtaaag
    10501 acagttttga aggttataca ttgactatcg gtaaaaaagt tatcggagaa attgccgaat
    10561 tagacggaca atttgccatt ataaagaatg ggaatgtcga tagtttttat aaaaaattgg
    10621 aaaaagctgt ggaaattttg attgaaaatt ataatttagc aaaataagtc ttgttttttt
    10681 gaaattttca tgatataata gtccatgttg attgtaggag agatagcgaa gaggctaaac
    10741 gcggcggact gtaaatccgc tccttcgggt tcgggggttc gaatccctct ctctccattt
    10801 cattaatggg gtatagccaa gcggtaaggc aagggacttt gactccctca tgcgttggtt
    10861 cgaatccagc taccccagtt cttaggtaat aatcaagata aaaagcaaaa tatcttaggg
    10921 tattttattt ttataattga aagacgtgaa tgatatgaac atgtccttgc gggtgcttag
    10981 gaaaaaaatt ataagtatgt caagtttaag aaaaacttga ttgttggagg attttttaga
    11041 tgaacgaatt tgaagatttg ctaaatagcg ttagtcaagt tgagactggt gatgttgtta
    11101 gtgctgaagt attgacagtt gatgcgactc aagctaacgt tgcaatctct ggaactggtg
    11161 ttgaaggtgt cttgactctt cgcgaattga caaacgatcg tgatgcagat atcaatgact
    11221 ttgttaaagt aggagaagta ttggatgttc ttgtacttcg tcaagtagtt ggtaaagata
    11281 ctgatacagt tacatacctt gtatctaaaa aacgccttga agctcgcaaa gcatgggaca
    11341 aacttgttgg tcgcgaagaa gaagttgtta ctgttaaagg aacgcgtgcc gttaaaggtg
    11401 gactttcagt agaatttgaa ggtgttcgtg gatttatccc agcttcaatg ttggatactc
    11461 gtttcgtacg taacgctgag cgttttgtag gtcaagaatt tgatactaaa atcaaagaag
    11521 ttaacgctaa agaaaaccgc ttcatccttt cacgtcgtga agttgttgaa gcagctactg
    11581 cagcagctcg cgctgaagta ttcggtaaat tggctgttgg tgatgttgta actggtaaag
    11641 ttgctcgtat cacaagcttc ggcgctttca tcgaccttgg tggtgttgac ggattggttc
    11701 acttgactga attgtcacat gaacgtaacg tatcaccaaa atcagttgta actgttggtg
    11761 aagaaattga agtgaaaatc cttgatctta acgaagaaga aggacgtgta tcactttcac
    11821 ttaaagcaac agtaccagga ccatgggatg gcgttgagca aaaattggct aaaggtgatg
    11881 tagtagaagg aacagttaaa cgtttgactg acttcggtgc atttgttgaa gtattgccag
    11941 gtatcgatgg acttgttcac gtatcacaaa tttcacacaa acggattgaa aatccaaaag
    12001 aagctcttaa agttggtcaa gaagttcaag ttaaagttct tgaagttaac gcagatgcag
    12061 aacgcgtgtc actttctatt aaagctcttg aagaacgtcc agcccaagaa gaaggacaaa
    12121 aagaagaaaa acgtgctgct cgtccacgtc gtccaagacg tcaagaaaag cgtgatttcg
    12181 aacttccaga aacacaaaca ggattttcaa tggctgattt gtttggtgat atcgaacttt
    12241 aatcaaattg aaaattcaca aaatcctttg tttactaaac aagggatttt tcttttgtct
    12301 ctgctccttt tttgatataa tagttctatg ttaaaatcag aaaaacaatc acgttatcaa
    12361 atgttaaatg aagaattgtc cttcctattg gaaggcgaaa ccaatgtttt ggctaatctt
    12421 tccaacgcca gtgctcttat aaaatcacgt tttcctaata ccgtatttgc aggcttttat
    12481 ttgttcgatg gaaaggaatt ggttttaggt cccttccaag gaggtgtttc ctgcatccgt
    12541 attgcactag gcaagggtgt ttgtggtgag gcagctcact ttcaggaaac tgttattgtt
    12601 ggagatgtga cgacctatct caactatatt tcttgtgata gtctagctaa aagtgaaatt
    12661 gtggtgccga tgatgaagaa tggtcagtta cttggagttc tggatctgga ttcttcagag
    12721 attgaggatt acgatgctat ggatcgagat tatttggaac aatttgtcgc tattttgctt
    12781 gaaaagacaa catgggactt tacgatgttt gaggaaaaat cttaatgtat caagcacttt
    12841 atcgaaaata tagaagtcaa aacttctccc agttagttgg tcaagaagtt gtggctaaga
    12901 ctcttaaaca agcggtggag caagagaaaa taagtcacgc ttatcttttt tctggtcctc
    12961 gtggaacggg aaaaaccagt gttgctaaaa tctttgccaa ggctatgaac tgtcccaatc
    13021 aagtgggtgg cgaaccttgc aataactgct atatttgtca agcagtgacg gacggtagtt
    13081 tagaagatgt cattgaaatg gatgcagctt ctaataatgg ggtagatgaa attcgcgaaa
    13141 ttcgtgataa atctacctat gcgcctagcc ttgctcgtta taaggtttat atcatagatg
    13201 aggttcacat gctgtctaca ggggctttta atgccctcct aaagacgctg gaagaaccaa
    13261 cacagaatgt agtctttatt ttggccacta ctgaattaca caagattcct gctactattc
    13321 tatcccgtgt gcaacgtttt gagtttaaat caattaagac acaggatatt aaggaacata
    13381 ttcactatat cttagaaaaa gaaaatatca gttctgaacc agaggctgtg gaaatcattg
    13441 ccagacgggc ggaaggtgga atgcgggacg ccttgtctat tttggatcaa gccctgagtt
    13501 tgacacaggg aaatgagctg acgactgcta tctctgaaga aattactggc actattagcc
    13561 tatcagcctt ggatgattat gtggcggcct tgtctcaaca ggatgttccc aaagctttgt
    13621 cttgcttgaa tcttcttttt gacaatggta agagcatgac tcgttttgtg accgatcttt
    13681 tgcactattt aagagacttg ttaattgttc aaacaggggg agaaaatact catcatagtt
    13741 cagtctttgt agaaaatttg gcacttcctc aaaaaaatct gtttgaaatg attcgcttag
    13801 caacagtgag tttagcagat attaagtcta gtttgcagcc caagatttat gctgaaatga
    13861 tgaccgtccg tttggcggaa atcaagcccg aaccagctct atcaggagcg gttgaaaatg
    13921 aaattgctac gctgagacag gaagttgccc gtctcaaaca agagctttct aatgtaggtg
    13981 cggttcctaa acaagttgca ccagctccta gtcgaccagc tacgggcaaa acagtctatc
    14041 gtgtcgatcg caataaagtg caatctatct tacaagaggc cgtcgaaaat cctgatttag
    14101 cacgtcaaaa tctaattcgt ttgcagaatg cctggggaga ggtaattgaa agtctaggtg
    14161 ggccggacaa ggctctgcta gttggttctc aaccggttgc tgccaatgaa caccatgcta
    14221 ttcttgcttt tgagtctaac ttcaatgctg gtcaaactat gaaacgagac aatctcaata
    14281 ccatgtttgg caatatcctc agtcaggcgg caggtttttc acctgagatt ttagctattt
    14341 ccatggagga atggaaagaa gttcgcgcag ccttttcagc caaagccaaa tcttctcaaa
    14401 ctgaaaaaga agtagaagaa agcctgattc cagaaggatt tgaatttttg gctgataaag
    14461 tgaaggtaga ggaagactaa agaaagattt cgtgatacaa taagtttatg aataaacaac
    14521 aatttattat tatggcgctg tttacagctg ctgagaccta ttttttcaat gaagcctgga
    14581 tgactggccg ctatattatg gcagcctttt gggcaatttt actctttaga aatttccgag
    14641 tcagttatgt gatgggcaaa atcgttgatg tcatcgatca gcattttaat aggaaagact
    14701 agccctcagc ttccagacaa aatcaaagcc ttttaggctt ttttttgtta tactagaaaa
    14761 gtatatttat agaatttttg ctctatttct ggggaaatca gacgtttttc tagtaagtac
    14821 tgtaaaagtt ttgaaaaaga aaggaactat catgtcagta ttagagatca aagatcttca
    14881 cgttgagatt gaaggaaaag aaattttaaa aggggttaac ctgaccctga aaacaggaga
    14941 aattgccgct atcatgggac caaatggtac aggtaaatcg actctttctg ccgctatcat
    15001 gggaaatcca aactatgaag taactaaagg tgaagttttg tttgatggcg taaacatcct
    15061 tgagttggaa gtggatgagc gtgcgcgtat gggacttttc cttgctatgc aatacccatc
    15121 agaaatccct ggaattacca atgctgagtt tcttcgtgcc gctatgaatg cgggtaaaga
    15181 agatgatgag aagatttcag ttcgtgagtt tattactagg ctagatgaaa aaatggaatt
    15241 gctcaacatg aaagaagaaa tggcagagcg ttacctcaac gaaggcttct ctggtggtga
    15301 gaaaaaacgc aatgaaattc ttcaactttt gatgttggag ccaacatttg ctcttttgga
    15361 cgagattgac tcaggtcttg atattgacgc tcttaaagtt gtgtctaaag gtgtcaatgc
    15421 catgcgtggt gaaggttttg gtgctatgat catcactcac taccaacgtc ttttgaacta
    15481 tatcacacct gatgtggtac acgtgatgat ggaaggtcgt gttgtccttt ctggtggtcc
    15541 agaattggct gcgcgtttgg aacgtgaagg atacgcaaaa ttagctgaag aacttggcta
    15601 cgactacaag gaagaattgt aatttcctcg tatcttttag gagaagtaaa tgactagaga
    15661 aaatattaaa cttttttcag aaatgcacgc tgaaccaagc tggttggctg atctccgtca
    15721 aaaagctttt gacaagattg agactttgga attaccagtt attgagcgtg tcaaattcca
    15781 ccgttggaat ctgggtgatg gaacgattac agaaaatgag ccatcagcaa atgttccaga
    15841 tttcacagct ttagatcatc acttgaagtt ggtgcaagta ggaactcaaa ctgttttcga
    15901 acaaactcca gttgagttag ctgaacaggg tgttgtcttc acagactttc actcagcttt
    15961 agaagaaatt ccagagctga tcgaagaatt cttcatgtca tctgttaagt atgatgatga
    16021 caagttggcg gcttaccaca cagcttactt taacagtggt gctgtactct atattccaga
    16081 taacgtagaa atcacagagc caattgaagg aattttctac caagatagcg atagcaatgt
    16141 gccgtttaac aagcatatta tgattatcgc tggtaaaaat tctaagatta attatctgga
    16201 gcgtttagag tcacgcggtg aaggaagtgc caaagcaact gctaatatca cagtagaagt
    16261 gattgcacgt tcaggtgcgc aagtcaagtt tgctgctatc gaccgtctag gtgaaaacgt
    16321 cactgcctac attagccgtc gtggtaaatt aggcaacgat gcaagtattg actgggctat
    16381 cggtgtcatg aacgaaggaa atgtcgttgc tgattttgat agtgacttga ttggtaatgg
    16441 tagctatgct gacctcaagg ttgtagctct ttcaagtggt cgtcaggtac aagggattga
    16501 tactcgtgta actaactatg gctgcaactc tatcggaaat atcctacaac atggggttat
    16561 ccttgaaaaa gcaactttga ctttcaatgg tatcggccac atcatcaagg gtgctaaggg
    16621 agcagatgcc caacaagaga gccgtgttct catgctttca gaccaagcgc gttcagatgc
    16681 taacccaatt cttttgattg atgaaaatga tgtcactgca ggacacgcag cgtctatcgg
    16741 acaagttgat ccagaagaca tgtattacct catgagtcgt ggattggata aggcaactgc
    16801 agagcgtttg gttgttcgtg gtttccttgg atctgttatc gtggagattc cagtcaagga
    16861 agttcgtgat gaaatgattg caactatcga agagaaattg tcaaaacgct aaggggaagc
    16921 ctatgttaga tgtagaagcg attcgcaagg attttccaat tttagatcag attgtcaatg
    16981 atgaacctct ggtctatctg gacaatgctg cgacgacaca aaaaccacta gtagttctga
    17041 aagctattaa cagttactat gagcaggaca atgccaatgt tcaccgtggt gtccatacct
    17101 tagcggaacg agcgacagct tcttatgaag ctgctcgtga aaccattcgt aagtttatta
    17161 atgcaggctc tacaaaggaa gttctcttta ccagaggaac gacaaccagc cttaactggg
    17221 tggcacgctt tgctgaggaa attctcactg agggagacca ggtcttgatt tcagtaatgg
    17281 aacaccattc taatatcatt ccatggcagg aagcttgtcg aaagactgga gcagagcttg
    17341 tctatgtcta tcttaaagac ggtgccttgg atatggagga tttgcgagct aaattgactg
    17401 ataaggttaa atttgtttcc ctagctcatg cctccaatgt tcttggtgtg gtcaatccga
    17461 tcaaggaaat cactcaatta gcccaccaag ttggggcaat catggtagtg gatggtgctc
    17521 aatctacacc tcatatgaag attgatgtcc aggacttgga tctggacttt ttcgcctttt
    17581 cgggtcacaa gatggctggt ccgactggta tcggtgtcct ttacggcaaa gaaaagtatc
    17641 ttgagcaaat gtctccagta gaatttggcg gcgagatgat tgattttgtc tacgagcaat
    17701 ccgctagttg gaaggaattg ccttggaaat ttgaggctgg aacgccaaat atggcaggag
    17761 ctattggact tgcgactgca gttgattatc tggaaaagat tggtatggat gccgttgaag
    17821 ctcatgaaca ggaattgatt gcgtacgtct atccaaaact gcaggcaatt gagggattga
    17881 ccatttacgg ttctcaggat ttggctcaac gttcgggtgt tattgccttt aacctaggtg
    17941 atctccatcc tcacgatctt gcgacggctc tggattatga aggagtggct gttcgtgctg
    18001 gtcaccattg tgcgcaaccc ttgcttcagt atttggaagt cccagcatca gctcgtgcaa
    18061 gtttttatat ctataatacc aaggcagatt gcgacaaact agtcgatgcc ctacaaaaga
    18121 caaaggagtt tttcaatggc actttctaaa ctagatagcc tttatatggc agtggtagca
    18181 gaccattcga aaaatccaca tcaccaaggg aagttagaag acgctgagca aatcagtctc
    18241 aacaatccga cttgtgggga tgtcatcaac ctctctgtca agtttgatgc agaggaccgt
    18301 ttggaagata ttgcttttct aaattcagga tgcacgattt caactgcttc tgctagtatg
    18361 atgacagatg ccgttttagg aaaaaccaaa caagaaattt tagaactggc gactattttt
    18421 tctgaaatgg ttcaagggca aaaagatgag cgtcaagacc aacttggaga cgcggcattc
    18481 ttgtcaggtg ttgccaaatt ccctcaaaga atcaagtgtg caaccctagc ttggaatgcc
    18541 cttaagaaaa caattgaaaa tcaagaaaaa cagtaagaca agtttctttt gtcttatgaa
    18601 ttattagaaa tgaagaaagg atattatggc tgaagaaaga gtagaaccaa aaccaattga
    18661 ccttggtgaa tataaatttg gtttccatga cgatgtagag cctgtcttat cgacaggaaa
    18721 aggactcaac gaaggtgtta ttcgtgaatt atctgctgct aagggtgagc ctgagtggat
    18781 gttggagttc cgtttgaagt cttatgaaac cttcaaaaaa atgcccatgc aaacttgggg
    18841 agcagacttg tcagagattg actttgatga cttaatctac taccaaaaac catctgacaa
    18901 accagcccgt tcttgggatg atgtacctga aaagattaaa gaaacctttg aacgtatcgg
    18961 gattccagaa gctgaacgtg cttatttagc aggggcttct gcccagtacg agtcagaagt
    19021 ggtttaccac aacatgaagg aagagttcca aaaattaggt attatcttta cagatacaga
    19081 ttccgcactc aaggaatacc cagacttatt taaacaatac tttgcgaagt tggtaccgcc
    19141 gacagataac aagttggcag ccctcaactc agcagtatgg tcgggtggaa cttttatcta
    19201 cgtgccaaaa ggtgtcaagg tagatattcc acttcaaact tatttccgta tcaataacga
    19261 aaatataggt cagttcgaac gtaccttgat tatcgttgat gagggagcaa gcgtccacta
    19321 cgtagaagga tgtacagcac caacatattc aagcaatagc ttgcacgctg ccattgtaga
    19381 aatttttgct ttggacggag cttatatgcg ttatacaact atccaaaact ggtctgataa
    19441 cgtctataac ttggtaacaa agcgtgctaa ggctcaaaag gatgccactg ttgagtggat
    19501 tgatggaaac ttgggtgcca aaacgactat gaaatatcca tctgtttatc ttgatggaga
    19561 aggagcgcgt ggtaccatgc tctctatcgc ctttgctaat gcagggcaac accaagacac
    19621 gggtgctaag atgattcaca atgctccaca taccagctcg tctattgtgt ctaaatccat
    19681 cgctaaaggt ggaggaaagg ttgactaccg tggacaagtc acctttaaca agaactctaa
    19741 gaaatctgtt tcccacattg aatgtgatac cattatcatg gatgacttgt cagcatcaga
    19801 tactattcca tttaatgaaa ttcacaactc gcaagtggct ttggaacacg aagccaaagt
    19861 atctaagatt tcagaagagc aattgtatta tctcatgagc cgtggattgt cagaatctga
    19921 ggcaactgaa atgattgtca tgggatttgt agaacccttt acaaaagaac ttccaatgga
    19981 atacgcagtt gagctgaacc gcttgattag ctatgaaatg gagggatcag ttggataaaa
    20041 tttgatttta tactcttcga aaatctcttc aaaccacgtc agcatcgcct taccgtatgt
    20101 atggttactg acttcgtcag tttcatctac aacctcaaaa cagtgttttg agcaacctgc
    20161 ggctagcttc ctagtttatt ctttgatttt gagtattaga tttactcaaa atcaaggatt
    20221 ttgaagatga acttgtatca aaaaatcgcg gtttaaaatc gcgatttttt ataatttctc
    20281 gttaacaaag cggacaaact gattccacca aacttttaag aagaaggctt tttcaatttt
    20341 cttgtctgct accatttcga aactagggcg ctctgtggtg atgtaacctt gaccaatcaa
    20401 gtccttgtct tcataagtca aatggccaac cactgttcca gcttcaagtg gtgctgggat
    20461 tgctttggaa tcaggtgtga attgaacaga ttgggaagat tgattcccaa cacgttcgat
    20521 tagatagata tcctctggag ccactgcagt tactgtatct tcttttccat cttgtacagg
    20581 ggctttgcta tcttgatagg catcgccttg ttgaacgatt ttgcgaagtg taaatgtaga
    20641 agaaatataa tccattaggg aagatgtagc tgtaaatcga gcgtaaggat tattgtcttg
    20701 atgatctgca tttaaaacaa ctgtgatgac tctcatgcct ttttcgacag tagtaccaac
    20761 aaaagactct ccagccttat ctgttgttcc tgtttttagc ccatcaaaac caccacggta
    20821 agcaggcata ccttctaaca tgtagttggt tgaagtgatt gtcatcccag caaaagtaga
    20881 agaaggtttt ttggtgattt ctaagacttg tgggtatttt ttgatgaggt tgcgagcaac
    20941 gatagcgaca tcataagcac taagcttatt ttcctcatct tttttagaac ctgggtaaat
    21001 gttatcccct agagtttcat tgttaagacc tgtcgtattg acaacagtgg catcctgaat
    21061 tccccattcc aagagttttg cccgcatcat atcgatgaaa tctttttctg agccagcaat
    21121 tttctcagct agggcaatag cggcgctgtt ggcactagat accagagttg cttcaagcaa
    21181 ctcttcgaca gtataattac gggcctccat aggaatatta ctggcttcag aatttgtcgt
    21241 caattgataa ggataatcag aaatatctac aggagtggag agggtaatac ttccgttttc
    21301 caaagcttca tagaccagat aagcagtaat caattttgtt atggaagcaa tttcgacagg
    21361 ttgcgttgca tccttctcat agagaatttt accagtattt gcctcaacag caatcgcatg
    21421 tttagcggca atggtaaaat cttgagcaac agcagtagaa gcacccccta aaagagagac
    21481 agttaacaaa gttaaaaata tttttttcat agtagtctta ttctatcata aagaaaaaaa
    21541 atattcttgc tttaataatt catctgttaa gctttttgaa aatatggtaa aataaagtga
    21601 gggaggtaac tcatgtttcg tagaaataaa ttattttttt ggaccacaga aattttactc
    21661 ttaaccatca tcttttacct atggagacag atggggtctt tgattaaccc ttttgttagc
    21721 gtgcttaata caattatgat tccattttta ttagggggct ttctttatta tttgacaaac
    21781 cctattgtta ctttcttaaa taaagtctgt aaactcaatc gtttgcttgg tattttaatt
    21841 accttgtgta ctttggtctg gggaatggtc ataggtgttg tctatctctt acctattttg
    21901 attaatcagt tatctagttt gattatatct agtcaaacta tttatagtcg agtacaagac
    21961 ttaatcatag acttatctaa ttatcctgcg ctccagaatt tggatgtaga agctacaatt
    22021 cagcagttaa acttatccta tgttgatatt cttcaaaata tcctaaatag cgtatcaaat
    22081 agtgtgggga gcgtcttgtc agctcttatc agtactgttt tgattttgat tatgactcca
    22141 gtttttttgg tttatttctt attagatgga cataaattct tgcccatgct tgaaagaacg
    22201 attctaaaga gggatcgctt gcatattgca ggcttattaa agaatttaaa tgcgacgatt
    22261 gctcgctata ttagtggagt ttcgattgac gcaatcatta taggttgttt ggcttatatt
    22321 ggctatagta ttattggttt aaaatatgct ttagtttttg ccattttttc tggtgtagcc
    22381 aatttaattc cttatgtggg gccaagtatt ggtttgattc ctatgatcat cgcaaatata
    22441 ttcactgatc cccatagact gctgattgca gtgatttata tgcttgttgt tcagcaggta
    22501 gatggcaata tcttatatcc tcgaatcgta ggaagtgtta tgaaggttca tccaatcacg
    22561 attttagttt tacttttgtt gtcaagcaat atctatggtg tagttggaat gattgtcgca
    22621 gtgccaacct attctatctt gaaagaaatt tctaagttct tatcccgttt gtatgaaaat
    22681 cataaaataa tgaaagaacg agaaagagaa ttagctaagt aaaagtcagg agaaccctga
    22741 tttttcttta ctggaagtgg cctttagatt agaagactga aaataagtta aagtcttaaa
    22801 ctaattttca cagctaagaa tagtagaagt taatctgata aaaatcgaaa aaaccagtgg
    22861 aattctgtgt cagggtaagt tccactggtt ttcatagtct attaaagttc gaatgaaacc
    22921 tatttatagt agattgaaac tagaatagta cacctctaat tctaaaacat tgttagaaat
    22981 cgatttgact gtcctgatct attcgttcta ttcttatttc attttactat attttggtgc
    23041 aataagtgaa aagtagtccg aataatataa ggattgattt tatagttttt aaactcaaat
    23101 gaattgaaat aaagagagta cgaaaattct catctgaaag tattttagaa taattctctt
    23161 cgtgaatttc ttcaaaacag atagcttcat cttaggtatg tgatttcttt ttgcattttt
    23221 gagttagata aggtataatg gttttattgt cttttggggt cgttacggat tcgacaggca
    23281 ttatgaggca tattttgcga ctcgtgtggc gacgtaaacg ctcagttaaa tataactgca
    23341 aaaaataaca cttcttacgc tctagctgcc taaaaaccag caggcgtgac ccgatttgga
    23401 ttgctcgtgt tcaatgacag gtcttattat tagcgagata cgattaagcc ttgtctagcg
    23461 gtttgataag agattgatag actcgcagtt tctagacttg agttatgtgt cgaggggctg
    23521 ttaaaataat acataaccta tggttgtaga caaatatgtt ggcaggtgtt tggacgtggg
    23581 ttcgactccc accggctcca ttattccttt gcattctttt gcattccttg gtaaaacgtt
    23641 gttaaatcaa cgttttttat ttttatcttt ggtattcctt tgcattcttt tgctaaaaag
    23701 ggagtcacaa acagacccta ttttaaaaaa aggatagaaa aaaggataca acatttgtcg
    23761 catcctaaaa ataatctttt ttccacggaa gacatgggat tcgaacccac gcacgctatt
    23821 acacgcctac cgcgtttcca acacggcctc ttaagcctct tgagtaatct tccaatactt
    23881 actcaaatag tctaccataa aggctcttat cttgcaataa aaattctaga aataagaaaa
    23941 atgatagatt ttgaaagaaa atgataaaaa atgcttgact tcaaaagaaa gtatgataga
    24001 atgaatagtg taaacgataa caggaggtga ttcggtgtta aaaacagagc ggaagcaact
    24061 gattttagag gagttaaatc aacatcatgt agtttctcta gaaaaattag ttagtttgct
    24121 agaaacgtca gaatcaacgg ttcgaagaga cttggatgag ttggaagcgg aaaacaagct
    24181 tcgtcgtgtg catggtggag cagaactccc ccactcctta caggaagaag aaaccattca
    24241 agaaaaatct gtcaaaaacc ttcaagaaaa gaagttgctg gctcagaaag cagcctctct
    24301 cattaaagaa aaagatgtca tctttatcga tgctggaaca acaactgctt ttttgattca
    24361 tgaattggtc aataagaata ttacagttgt gaccaactcc attcaccatg ccgctcagtt
    24421 ggttgaaaag cagattccaa ctgtcatggt tggaggaaac gtcaagacgg cgacagatgc
    24481 tagtatcggt ggcgttgctc ttaaccagat taaccaattg cactttgacc gtgcctttat
    24541 cggaatgaat ggtgttgacg atggctatta tacgactcct gatatggagg agggagctgt
    24601 gaaaagagct attttggaga atgccaagca gacctacgtc ttggtggatt cgtcaaaaat
    24661 tggacaaact tgctttgcca aggtagcacc actcaaacgc gctatcgtta tcactagtca
    24721 agggcatgag ctcttgcagg ttattaagga gaaaacggag gtaatagaag tatgatttat
    24781 acagtcacac tcaatccatc cattgactat atcgttcgtt tggaccaagt caaagttggt
    24841 agtgtaaatc gtatggacag tgatgataag tttgctggtg ggaaaggaat caatgtcagc
    24901 cgtgtcttga aacgtttgaa tataccaaat acagcgacgg gatttatcgg tggctttact
    24961 ggtaaattta tcacagatac tttagcagag gaagaaatcg agacacgttt tgtccaggtg
    25021 gcagaagata ctcgtatcaa tgttaaaatc aaagcagacc aagaaacaga aatcaacgga
    25081 acgggtccaa ctgttgaatc ggttcagcta gaagaattga aagctatttt atctagtctg
    25141 acagcagaag atacagttgt ctttgcaggt tcaagtgcta aaaatctagg caatgttatc
    25201 tataaggatt tgatttcctt gacgcgccag actggtgcgc aagtggtctg tgactttgaa
    25261 ggacagacct taattgatag tttggactac cagcctcttc ttgtaaaacc aaacaatcat
    25321 gaacttggag cgatttttgg ggttaaactc gaaagtttag atgaaattga gaaatacgct
    25381 cgtgagttac tggctaaggg tgctcaaaat gttattatct ctatggctgg tgatggtgcc
    25441 cttcttgtca catctgaggg agcttacttc gctaaaccaa tcaaaggaac agtcaaaaat
    25501 tcagttggag ctggtgattc tatggttgct ggattcacag gtgaatttgt caaatcaaaa
    25561 gacgtagtag aagccttcaa atggggagtg gcttgcggaa cggcaactac cttctcagat
    25621 gacttggcaa cggcggaatt tattaaagaa acatatggaa aagttgaggt agaaaaacga
    25681 tgaaaattca agacctattg agaaaagatg tcatgttgct agatttgcag gcaactgaaa
    25741 aaacagctgt catcgacgag atgattaaaa atttgacaga ccacggttat gtaacagatt
    25801 ttgaaacatt taaagaagga attttggcgc gtgaagcttt gacttctact ggtttgggtg
    25861 atggaatcgc aatgcctcac agcaaaaacg ctgctgtcaa agaagcgaca gttctatttg
    25921 ctaagtcaaa taagggtgtt gactacgaga gcttggatgg acaagcaact gacctcttct
    25981 tcatgattgc agctccagaa ggtgccaatg atactcactt ggcagccttg gcagaattgt
    26041 ctcaatactt gatgaaagac ggttttgcag acaaacttcg tcaagcaaca tctgcagacc
    26101 aagttatcga actttttgac caagcttcag aaaaaactga ggaacttgtt caagcacctg
    26161 ctaatgactc tggtgacttt atcgtagctg ttacagcttg tacaacaggt attgcccaca
    26221 cttacatggc ccaagaagcc cttcaaaaag tagctgctga aatgggggtt ggtatcaagg
    26281 tcgaaaccaa cggtgctagc ggtgttggaa atcaactaac tgcagaagat atccgtaagg
    26341 ctaaagctat tatcattgca gcagacaagg ccgttgaaat ggatcgattt gatggaaaac
    26401 cattgatcaa tcgtccagtt gctgacggta tccgtaagac agaagagcta attaacttgg
    26461 ctctttcagg agatactgaa gtctaccgtg ccgctaatgg tgccaaagct gcaacagcct
    26521 ctaacgaaaa acaaagcctt ggtggtgcct tgtacaaaca cttgatgagt ggtgtatctc
    26581 aaatgttacc attcgttatc ggtggtggta tcatgattgc ccttgccttc ttgattgacg
    26641 gtgctttggg tgttccaaat gaaaaccttg gcaatcttgg ttcttaccat gagttagctt
    26701 ctatgttcat gaaaattggt ggagctgcct ttggtttgat gcttccagtc tttgcgggtt
    26761 atgttgccta ctctattgct gaaaaaccgg gtttggtagc aggtttcgtg gctggtgcta
    26821 ttgccaaaga aggttttgcc tttggtaaaa ttccttatgc cgcaggtggt gaagcaactt
    26881 caactcttgc aggtgtctca tctggtttcc taggtgccct tgttggtgga tttatcgcag
    26941 gtgccttggt tcttgccatc aagaaatacg ttaaagttcc tcgttcactc gaaggtgcta
    27001 aatcaatcct tctattgcca cttcttggaa caatcttgac aggatttgtt atgctagctg
    27061 tgaatatccc aatggctgca atcaacactg ctatgaatga cttcctaggc ggtcttggag
    27121 gaggttcagc tgtccttctt ggtatcgtcc ttggtggaat gatggctgtt gacatgggtg
    27181 gaccagttaa taaagcagct tatgtctttg gtacaggtac gcttgcagca actgtttctt
    27241 caggtggttc tgtagccatg gcagcagtta tggctggagg aatggtgcca ccacttgcaa
    27301 tctttgtcgc aactcttctt ttcaaagata aatttactaa ggaagaacgt aactctggtt
    27361 tgacaaacat catcatgggc ttgtcattta tcactgaggg agcgattcca tttggtgccg
    27421 ctgacccagc tcgtgcgatt ccaagcttca tccttggttc agcagtagca ggtggactcg
    27481 ttggtcttac tggtatcaaa ctcatggcgc cacacggagg aatcttcgtt atcgccctta
    27541 cttcaaatgc tctcctttac ctcgtttctg tcttggtagg agcaatcgta agtggtgtgg
    27601 tttatggtta cctacgcaaa ccacaagcat aaaaaataga aaaatgaaaa gattggaccg
    27661 tttggtgcag tctttttctc ttcccgaaat gcctgtgaaa tatggtataa tagaagaatg
    27721 gcaaacaaga atacaagtac aacaagacgg agaccgtcta aagcagaact ggaaagaaaa
    27781 gaagcgattc aacgaatgtt gatttcgtta ggaattgcga ttttattgat tttcgcagcc
    27841 ttcaaattag gggctgcagg tataaccctt tataatttaa ttcgcttgct agtgggtagc
    27901 ctagcttatc tggcgatatt cggcctatta atctatctct tctttttcaa gtggatacga
    27961 aaacaggaag gactcttatc tggctttttc accatatttg ctggcttact cttgattttt
    28021 gaggcctact tggtttggaa atatggtttg gacaagtccg ttctaaaagg gaccatggct
    28081 caggttgtga cagatctgac tggttttcga acgactagct ttgctggagg gggcttgatc
    28141 ggggtcgctc tttatattcc aacagccttt ctcttttcaa atatcggaac ttactttatt
    28201 ggttctatct tgattttagt gggttctctc ctagtcagcc cttggtctgt ttacgatatt
    28261 gctgaatttt tcagtagagg ctttgccaaa tggtgggaag ggcacgagcg tcgaaaagag
    28321 gaacgctttg tcaaacaaga agaaaaagct cgccaaaagg ctgagaaaga ggctagatta
    28381 gaacaagaag agactgaaaa agccttactc gatttgcctc ctgttgatat ggaaacgggt
    28441 gaaattctga cagaggaagc tgttcaaaat cttccaccta ttccagaaga aaagtgggtg
    28501 gaaccagaaa tcatcctgcc tcaagctgaa cttaaattcc ctgaacagga agatgactca
    28561 gatgacgaag atgttcaggt cgatttttca gccaaagaag cccttgaata caaacttcca
    28621 agcttacaac tctttgcacc agataaacca aaagatcagt ctaaagagaa gaaaattgtc
    28681 agagaaaata tcaaaatctt agaagcaacc tttgctagct ttggtattaa ggtaacagtt
    28741 gaacgggccg aaattgggcc atcagtgacc aagtatgaag tcaagccggc tgttggtgta
    28801 agggtcaacc gcatttccaa tctatcagat gacctcgctc tagccttggc tgccaaagat
    28861 gtccggattg aagcaccaat ccctgggaaa tccctaatcg gaattgaagt gcccaactcc
    28921 gatattgcca ctgtatcttt ccgagaacta tgggaacaat cgcaaacgaa agcagaaaat
    28981 ttcttggaaa ttcctttagg gaaggctgtt aatggaaccg caagagcttt tgacctttct
    29041 aaaatgcccc acttgctagt tgcaggttca acgggttcag ggaagtcagt agcagttaac
    29101 ggcattattg ctagcattct catgaaggcg agaccagatc aagttaaatt tatgatggtc
    29161 gatcccaaga tggttgagtt atctgtttac aatgatattc cccacctctt gattccagtc
    29221 gtgaccaatc cacgcaaagc cagcaaggct ctgcaaaagg ttgtggatga aatggaaaac
    29281 cgttatgaac tctttgccaa ggtgggagtt cggaatattg caggttttaa tgccaaggta
    29341 gaagagttca attcccagtc tgagtacaag caaattccgc taccattcat tgtcgtgatt
    29401 gtggatgagt tggctgacct catgatggtg gccagcaagg aagtggaaga tgctatcatc
    29461 cgtcttgggc agaaggcgcg tgctgcaggt atccacatga ttcttgcaac tcagcgtcca
    29521 tctgttgatg tcatctctgg tttgattaag gccaatgttc catctcgtgt agcatttgcg
    29581 gtttcatcag gaacagactc ccgtacgatt ttggatgaaa atggagcaga aaaacttctt
    29641 ggtcgaggag acatgctctt taaaccgatt gatgaaaatc atccagttcg tctccaaggc
    29701 tcctttatct cggatgacga tgttgagcgc attgtgaact tcatcaagac tcaggcagat
    29761 gcagactacg atgagagttt tgatccaggt gaggtttctg aaaatgaagg agaattttcg
    29821 gatggagatg ctggtggtga tccgcttttt gaagaagcta agtctttggt tatcgaaaca
    29881 cagaaagcca gtgcgtctat gattcagcgt cgtttatcag ttggatttaa ccgtgcgacc
    29941 cgtctcatgg aagaactgga gatagcaggt gtcatcggtc cagctgaagg taccaaacct
    30001 cgaaaagtgt tacaacaata aaaaaatagc ttctttccaa gtttggaggg aagctatttt
    30061 agtggctatt gattgctttt attttctgaa gttggcgcat tggactgttt ttcgttttca
    30121 gtagcaggtt tacttgaagc aggagtagaa gagtcctgag ttgctgtttt ctgatcttct
    30181 tttttctctt ccttgacgct agattttggt gtttcctctt gctgtgtttt ttcttgacta
    30241 gtgttagtct ctttagttgg actggtgttt tccttagggg attccttttg gatttctttg
    30301 acaatggttg tcgtctggct tgtcgtaggt tcttttttaa tatttttgtt attatccaag
    30361 gcgttcataa tcgtgatact tgcggtaatc aagccaagga tactagcgat tgtagcaacg
    30421 gttttttgaa agactgtaaa gccttttttg atgtgttctg tttttggttt tgaagttcta
    30481 cgatagttag acatacattc tctcctttga ttatgattta ttatactctg tttctttaaa
    30541 aaaatcttaa aaaaagagaa atttcccttt cttgtcgcaa gctccgtttc atgatacaat
    30601 agaggaagtg attttagaaa gcgtgagaaa catgatttac tttgataatt cagcgacgac
    30661 caagccttat cctgaagccc ttgaaaccta tatgcaggtc gcttcaaaaa ttttaggaaa
    30721 cccatctagt ctccatcgtt tgggagacca agcaacacga atcttagatg cttctcgcca
    30781 acagattgca gatttaatcg gtaagaaaag cgatgaaatc ttctttacct cgggtggaac
    30841 agaaggggat aactggctta tcaagggtgt ggcctttgaa aaagctcagt ttggcaagca
    30901 catcattgtt tcagccattg aacatccagc agtcaaagag tcagccctct ggttgaaaag
    30961 tcaaggattt gaagtggatt ttgctccagt tgataagaaa ggcttggtcg atgttgaggc
    31021 gttagcaggt ttgatacggc atgatacaat cctcgtttcc atcatggctg tgaacaatga
    31081 aatcggctct atccaaccta ttgaggctat ttcagaattc ttggcagaca agccgactat
    31141 ttccttccac gttgatgcgg ttcaggcgct tgccaaaatt ccgactgaaa agtatctgac
    31201 agaacgggtg gattgcgcga ctttctctag tcacaagttc cacggggttc gaggtgttgg
    31261 ctttgtctat atcaaatctg gcaagaagat tacacctctt cttacaggtg gtggccagga
    31321 gcgagattat cgttcgacaa ctgaaaatgt ggcagggatt gcagcgacag ccaaggccct
    31381 ccgtttgtct atggaaaagc tagatatctt taggagcaag actgggcaga tgaaggcagt
    31441 gattcgccaa gctcttctga actatccgga tatttttgtc ttttcagatg aggaaaactt
    31501 tgcacctcat attctgactt ttggaatcaa aggtgttcga ggtgaagtca tcgttcacgc
    31561 ctttgaagac tatgatattt tcatctcaac aacctcagct tgttcatcta aggcaggaaa
    31621 accagccggt accttgattg ccatgggagt ggacaaagat aaggccaagt cagctgtgcg
    31681 tcttagccta gacttggaaa atgatatgag tcaggtcgag cagtttttga ccaagttaaa
    31741 attgatttac aatcaaacta gaaaagtaag ataggagcat tcatgcagta ttcagaaatt
    31801 atgattcgct acggagagtt gtcaaccaag ggtaaaaacc gtatgcgttt catcaataaa
    31861 cttcgtaata atatttcgga cgttttgtct atctataccc aagttaaggt aacagcagat
    31921 cgcgaccgtg cccacgctta cctcaatgga gctgattaca cagcagttgc agaatctctc
    31981 aaacaagttt ttggaattca aaacttttct cctgtttata aggttgaaaa atctgtagaa
    32041 gttttgaagt cttctgtcca agagattatg cgggacatct acaaggaagg tatgaccttt
    32101 aagatttcta gcaagcgtag cgaccacaac tttgaacttg atagtcgtga actcaaccaa
    32161 acacttggag gggctgtatt cgaagccatt ccaaatgtgc aagttcaaat gaaaagtcct
    32221 gacatcaatc ttcaggtgga gattcgtgaa gaagcagcct atctttctta tgaaaccatt
    32281 cgtggggctg gtggtttgcc agttggaact tcaggtaaag ggatgctcat gttgtcagga
    32341 gggattgact cacctgtagc aggttatctt gctcttaagc gtggggtgga tatcgaggca
    32401 gttcactttg ctagtccacc atatactagt cctggtgccc tcaagaaagc gcaggacttg
    32461 acccgtaaat tgaccaagtt tggcggaaat atccagttta tagaggtgcc tttcacagag
    32521 attcaagagg aaatcaaagc caaagcgcca gaagcttatt tgatgactct aactcgtcgc
    32581 tttatgatgc ggattactga ccgtattcgt gaggtacgaa atggtttggt tatcatcaat
    32641 ggggaaagtc taggtcaagt agccagccaa acccttgaaa gtatgaaggc tatcaatgct
    32701 gttaccaaca ctcccatcat tcgtcctgtg gttaccatgg acaagttgga aatcattgac
    32761 atcgcccagg aaatcgatac ctttgacatt tcaatccaac cgtttgaaga ctgttgtacc
    32821 atttttgcac cagatcgtcc aaaaacaaat cctaaaatta agaatgcgga gcagtacgaa
    32881 gcgcgtatgg atgttgaagg cttggttgag cgagcagtgg ctggaatcat gattactgaa
    32941 atcacacctc aagccgaaaa agatgaagtt gatgacttga ttgacaatct gctctaattc
    33001 agaaaatcca aaagaatagc gaaaatcagt aaaaaaagtt agttttttct ctaaaaacag
    33061 gtaaaaaact aacttttttt atttttatga tataatgata taaaattttg aatatagaga
    33121 gttttctgac aatgaatcaa tcctactttt atctaaaaat gaaagaacac aaactcaagg
    33181 ttccttatac aggtaaggag cgccgtgtac gtattcttct tcctaaagat tatgagaaag
    33241 atacagaccg ttcctatcct gttgtatact ttcatgacgg gcaaaatgtt tttaatagca
    33301 aagagtcttt cattggacat tcatggaaga ttatcccagc tatcaaacga aatccggata
    33361 tcagtcgcat gattgtcgtt gctattgaca atgatggtat ggggcggatg aatgagtatg
    33421 cggcttggaa gttccaagaa tctcctatcc cagggcagca gtttggtggt aagggtgtgg
    33481 agtatgctga gtttgtcatg gaggtggtca agccttttat cgatgagacc tatcgtacaa
    33541 aagcagactg ccagcatacg gctatgattg gttcctcact aggaggcaat attacccagt
    33601 ttatcggttt ggaataccaa gaccaaattg gttgcttggg cgttttttca tctgcaaact
    33661 ggctccacca agaagccttt aaccgctatt tcgagtgcca gaaactatcg cctgaccagc
    33721 gcatcttcat ctatgtagga acagaagaag cagatgatac agacaagacc ttgatggatg
    33781 gcaatatcaa acaagcctat atcgactcgt cgctttgcta ttaccatgat ttgatagcag
    33841 ggggagtaca tctggataat cttgtgctaa aagttcagtc tggtgccatc catagtgaaa
    33901 tcccttggtc agaaaatcta ccagattgtc tgagattttt tgcagaaaaa tggtaagtta
    33961 agaaaggaaa aaacgaaatg catattgaac atcttagcca ctggagtggt catcttaacc
    34021 gtgaaatgta ccttaaccgt tatggacatg gtgggattcc agttgtggtc tttgcttcat
    34081 caggtggtag tcacaacgaa tactatgatt ttggcatgat tgatgcctgt gcttccttta
    34141 tcgaggaagg ccttgtccag ttctttaccc tatctagttt ggatagtgag agctggttgg
    34201 ctacttggaa aaatgctcat gaccaagcgg aaatgcaccg tgcctacgaa cgttatgtga
    34261 ttgaggaggc cattctttta tcaagcacaa gacaggttgg tttgatggca tgatgacgac
    34321 aggttgctct atgggagcct atcatgcact caatttcttc ctccagcatc cagatgtctt
    34381 taccaaagtg attgctctca gtggtgttta cgacgcacgt ttctttgtcg gtgattacta
    34441 caacgatgat gctatttacc aaaactcgcc agtagattat atttggaacc aaaacgacgg
    34501 ctggtttatt gaccgttacc gtcaggcaga gattgtgctg tgtacggggc ttggagcctg
    34561 ggaacaagat ggtttgccat ccttttacaa gctcaaagaa gcctttgaca agaaacaaat
    34621 tccagcctgg tttgctgaat ggggacatga tgtcgcccat gactgggaat ggtggcgtaa
    34681 acaaatgcct tatttcctcg gtaatctcta tttataaaag gagttaccta tgaattacct
    34741 tgttatttct ccctactatc cacaaaactt tcaacagttt accatcgaac tagctaataa
    34801 aggcatcaca gtcttgggaa ttggtcaaga gtcttacgag caattggatg agcccttgcg
    34861 caatagcttg accgagtatt ttcgtgttga taatcttgag aacatagatg aagtcaaacg
    34921 tgcagttgct tttctctttt ataaacatgg tccaattggc cgcatcgagt ctcacaatga
    34981 atactggctt gagctagacg caacactcag agaacaattc aatgtttttg gtgccaaacc
    35041 agaggatctc aaaaagacga aatataagtc tgaaatgaag aaacttttca aaaaagcagg
    35101 tgttcctgtg gtacctggag ctgttatcaa gacggaagca gatgttgatc aagcagtgaa
    35161 agaaatcggt cttccaatga ttgccaaacc tgataatgga gtgggagcag ccgcaacctt
    35221 taaacttgag acagaagacg atatcaatca cttcaagcaa gaatgggacc attcaaccct
    35281 ttatttcttt gaaaaatttg tcacttccag cgaaatctgt acctttgacg ggctcgtgga
    35341 caaggatgga aagattgtct tctcaacaac ctttgactac gcctatacac cgcttgacct
    35401 catgatttat aagatggaca attcttatta tgtgctcaag gatatggatc ctaaactgcg
    35461 caagtatggg gaagcaattg tcaaagaatt tggtatgaaa gaacggtttt tccatattga
    35521 gttcttccgt gagggggacg attatattac catcgagtac aataaccgcc ctgcaggtgg
    35581 ttttaccatt gatgtttata actttgctca ttccttggac ctttatcgtg gctatgcagc
    35641 tattgtcgca ggagaggagt tcccggcgtc agactttgaa actcagtatt gtttggctac
    35701 ttctcgccgt gcaaatgctc actatgttta ttcagaagag gatttgcttg ccaaatatag
    35761 ccagcagttc aaggttaaaa aagtcatgcc agctgccttc gcggaacttc aaggagatta
    35821 cctgtatatg ctgaccactc cgagtcgaca agaaatggag cagatgattg cagatttcgg
    35881 acaacgtcaa gaataagaac tatcggatta aggaaattaa ctcccttaat ccttttgttt
    35941 tgtctgataa aaaataagag catcccaaca aggtagctat cataaaactt gttcgataac
    36001 tatttgaagc aggattaggt ggtcagaaat taaattttaa tatttcaatt gagtcatagt
    36061 attgtgtttg cgtatcctta aatcagctaa aaggatccat gacgacacct atacgatata
    36121 gttttcaaga taccaaacaa gtctattaat attcaatgaa aatcaaagag caaactagga
    36181 agctagccgc aggtttctca aaacactgtt ttgaggttgt ggatagaact gacagagtca
    36241 gtatcatata cctacggcaa ggtgaagctg acgtggtttg aagagatttt cgaagagtat
    36301 aaaatattca ggtgacgcat agatatagtt aattgaagct ttgtttgaaa tctgataaaa
    36361 taatgatatt actaagtttt aaaaactaaa gaaaagggaa gatatgatta caggcgaatt
    36421 aaaaaataaa atcgatcagc tgtgggaaat tctttggaca gaaggaaacg caaatccttt
    36481 aacaaatatt gaacagttga cttatctctt atttatgaaa gatttggata gtgtcgagct
    36541 tggacgtgaa agtgatgctg aatttctagg gattccttat gagggagttt ttccaaaaga
    36601 taaacctgaa taccgttggt caacttttaa aaatatagga gatgctcagg aagtttatcg
    36661 tttaatgact caggagattt ttccgtttat taaaaatctc aagggggata cagatgatac
    36721 agccttttca cgatatatgc gagaagctat ttttcaaata aataaacctg ctacgcttca
    36781 aaaggcaatt tctatcttag atgtttttcc aactagggga ttagatgtag attttgataa
    36841 tgacaaacaa agtattactg atatcggaga tatctatgaa tatctgttat caaaattgtc
    36901 gaccgcaggt aaaaatggac agttccgtac acctcgtcac atcatcgata tgatggttga
    36961 gttgatgcaa ccgactatca aagatatcat ctcagatccc gctatgggtt ctgctggctt
    37021 cttagtatct gctagccgtt acttaaagcg taagaaagat gaatgggaaa ccaatacaga
    37081 taatatcaat cattttcata atcagatgtt tcatggaaat gatacggata cgactatgtt
    37141 gagacttggg gcgatgaaca tgatgctaca tggagtagaa aatccacaaa tcagttacct
    37201 tgactcgctg tctcaagata atgaagaagc cgataaatat actttggttt tagcaaatcc
    37261 tccttttaag ggctcacttg actacaattc aacctctaat gaccttcttg caaccgtaaa
    37321 aaccaaaaaa acagaattac tctttctttc tcttttcttg cgaactttaa aaccaggtgg
    37381 acgagcagca gttatcgtac ctgatggtgt cctttttggt tcgtctaaag ctcataaagg
    37441 aattcgtcag gaaattgtag agaatcataa gcttgatgct gtaatctcaa tgcctagtgg
    37501 tgtgttcaag ccttatgctg gagtttcaac tgccattctc atctttacaa aaactggtaa
    37561 tggtggtact gacaaagtct ggttttacga tatgaaagcg gatggtttaa gtttggatga
    37621 taagcgacaa ccgattagcg acaatgatat tccagatatt atcgaacgct ttcatcatct
    37681 tgaaaaagaa gcagaacgtc agagaacgga tcaatctttc tttgttccag ttgctgagat
    37741 aaaggaaaat gattatgatt tgtctatcaa taaatataaa gagattgagt atgaaaaagt
    37801 tgagtatgaa ccaacagagg tcatcttaaa gaaaatcaat gatttagaaa aagaaattca
    37861 agctggcttg gctgaattag aaaaattact caagtagaga ggtggctgta tgaaaaaagt
    37921 gaagttgggg gaagtcttat ctctaaaaaa aggcaagaaa gccactgtac ttgctgaaca
    37981 aacaactcta agccaacgtt atattcaaat agatgattta agaaataata ataatttaaa
    38041 attcactgaa agtttaaata tgactgaagc actcccagat gatattctga tagcatggga
    38101 tggagctaat gcaggaacag ttggttatgg attatcggga gctgttggta gtacaattac
    38161 ggtcttaaaa aagaatgagc gatacaaaga aaaaattata tcagattact tgggagtctt
    38221 tttggaaagt aaatcgcagt atttacgaga acattcaaca ggtgcaacaa ttcctcattt
    38281 aaacaagaat atattacttg atttacaatt agaattgcta ggtatcgaag aacaagagaa
    38341 cattatctgt attcttaata cgattaaaag gcttattact aaaagaaaat tgcagttaga
    38401 tgaactaaac ttgctcgtca aatcccgatt taacgagatg tttggggatg ttattctaaa
    38461 tgaaaaagaa tggaaagtta gcaaatggaa cgagattcta acaataagaa atggtaaaaa
    38521 tcaaaaacag gttgaagatg ctgatgggaa atttcctatt tatggaagtg ggggaattat
    38581 gggatatgct aaagattgga tagtgaagaa aaattcagtt attattggac gtaaaggaaa
    38641 tataaataaa cctattttag ttagagaaaa tttttggaat gtagatacag catttggatt
    38701 agagcctgtt ttagaaaaaa taaactcaga atatttattc tatttttgtc aattatacaa
    38761 ttttgagaag ttaaataagg ctgtaacaat acctagttta actaaatcag atttattaaa
    38821 tatttccatc cccctccccc cactagccct ccaaaatgag ttcgcagact ttgtagccct
    38881 ggtcgacaaa tcacaatttg cttgtgagat agctataaaa gtgtggagaa atagcttgaa
    38941 atttagtata atatagctaa actatttgtt taaagtgaga aaaaaatggg aaattttagc
    39001 tttcttttaa aaaatgacga atatgaatct ttttcaaaac cttgcattga agctgagaat
    39061 atgattgcta catcaactgt ggctactgcc tttatggcgc gtcgtgcttt agagcaggct
    39121 gtccattgga tatatagtca cgattcatat ttagaagctc cctatcgtgc tactctatct
    39181 tctttagtat gggatgatga ttttagggat atcgtagatt ctgaactcca caagcagata
    39241 gttctgttga ttcggtgggg aaaccatgct gctcatggtg gtgaaattaa ggaacgagaa
    39301 gcgattttag ctttgcatca tttgtatcag tttgttaatt ttatcgatta ttgttacagc
    39361 aatgagtttg tggagcgtta ttttgatgag aagtgcttac cactttcagc aaacatcaaa
    39421 taccgagaaa ctccacaatc tatgataaag ttacaagaca gtttaccaga actgcctgat
    39481 tttcatgaac agatggctgc tcagtccgta gaagttcaag agacttatac tgaaaaacgt
    39541 gagactgcag cgcaacggca agatgtgcct ttccatattg atcaattatc tgaggcagag
    39601 acaagaaagc tctttattga tatcgatctc cgtttagcag gatggatatt tgaagaaaac
    39661 tgtcgtgttg agatagccgt tgatggtctc aagcacggtt caggaattgg ttactgtgac
    39721 tatgtacttt atggtaaaaa tgggaaaatt ttagcgattg tggaggctaa aaaagcctct
    39781 gtcaatccag aagtagggga agtacaggtc aaagaatatg ctgaagcttt ggagaaacat
    39841 atcggctatc agccaatttg ctttattaca aatgggttga agcactatat acttgatggt
    39901 ccgaaccgcc gccagattgc aggcttttac tctcaagaag aattgcaatt agtgatggat
    39961 agacgtcatc ttcaaaaacc gcttgaggat atttctagta aaattaggga cgatatttcc
    40021 gggcgtcact accaaaaaca tgccattgca agcgtttgtg aagctttctc tgatcatcgt
    40081 agacaggcac ttttggttat ggcaactggg gcggggaaaa ctcgtacagc agtttctcta
    40141 gttgatatct tatcacgtca taactgggta aaaaacgttc tcttcttagc cgatagaact
    40201 tccttggtta agcaagcata tgattcgttt agaaaattac tcccagatct ttccgtttgt
    40261 aacttcttag aagataaaga aggagctcaa tcaagtcgaa tggtcttttc aacttatccg
    40321 accatgattg gagcgattag tggtcaagaa gaagtaaatc aacgcccttt tactgttggg
    40381 cattttgacc ttatcataat tgacgaatct caccgttcta tttatcagaa atacaagtcc
    40441 atttttgatt attttgatgc aaggattgta ggcttaacag ctactccgcg tcaagattta
    40501 gataaaaaca cctatggatt ctttaatttg gagaatgggg ttccaacata tgcatatgat
    40561 ttggaagagg ctgttaaaga cggatattta gtagcctatc attctatcga aaccaaactg
    40621 aaactaccta cggatggtct acattatgat gatttgtccg aagaagaaaa ggaacatttt
    40681 gatagcaaat ttgaagacga tagctgtgaa aaagatattg atgggagtgt gtttaattcc
    40741 tttattttca ataaaagtac agtagaaatt gttttaaatg aactcatgac aagaggaatt
    40801 cagacagcct cgggtgatga aattggtaaa actattattt ttgctaaaaa tcatgaccat
    40861 gcggaatata tcagaggtat ttttaacaac cgctatcctg aaaaagggag cgactatgct
    40921 caggtgattg attatagtat taagcattat cagaccttga ttgatgattt taaaattaag
    40981 gagaagtatc ctcaaattgc gatttctgtc gatatgttag atacaggtat tgatgtacca
    41041 gaggttgtta atttagtctt cttcaagaaa gtacgctcta aaactaagtt ttggcagatg
    41101 attggtcgag gaacccgtct atgtaaagat ttatttggac ctgagcagga taaggaaaac
    41161 ttcttggtat ttgattatgg ggacaatttt gattattttc gtgcagatcc aagagatgga
    41221 gagggtcgtc acattgtttc gctgactcag cgtttattta atatcaaagt ggacttgatt
    41281 cgagaacttc agggactcca ataccaagaa gatcagtttg cgagagcata ccgtcagcag
    41341 cttgtctcgg aacttcaagg tcgtatagag agcttaaatg agttggactt cagggttcgt
    41401 atggttttag atacagttta tagctatagg aaattggaaa gttggcagaa tctaactgct
    41461 gttacaagtg aaaccattca aaaaaatctc tctccgcttt tatttgatga agataaagaa
    41521 gatgagatgg cgaggagatt tgatttgtgg ttgcttcata ttcagttggg gcaactgaca
    41581 gctaaatctt ccactgttca tatttcccaa gtgatgaaga cggctagagc tctttctgct
    41641 attggcaata tcccgcaggt ttttgagcag gctgaaatta tggctctttg tcaactgtag
    41701 tgggttgaaa aaaagctaag cttgagaaag gacaaatttt gtcctttctt ttttgatatt
    41761 cagggcgata aaaatccgtt ttttgaagtt ttcaaagttc cgaaaaccaa aggcattgcg
    41821 cttgataagt ttgatgagat tattggtcgc ttccagtttg gcattagaat agtgtagttg
    41881 aagggcgttg acgattttct ctttgttctt tagaaaggtt ttaaagacag tctgaaaaag
    41941 aggatgaacc tgcttcagat tgtcctcaat gagtccgaaa aatttctcag ggtctttgtt
    42001 ctgaaagtga aaaagtaaga gttgatagat ctgatagtgg tgtttcaagt cttctgaata
    42061 gcttaaaatc ttgtcaagaa tttctttatt tgttaagtgc atgcgaaaag tagggcgata
    42121 aaaacgttta tcgctcaatt tacgactatc ctgttggatg agtttccagt aacgcttgat
    42181 agccttgtat tcatgagatt ttcgttcaaa ctgattcata atttgaacac gaaaacgact
    42241 catggcacgg ctgagatgtt ggataatatg gaaacgatct agaacgattt tagcacacgg
    42301 aaaaagctgt ttagccaagt catagtaagg actaaacata tccatcgtaa tgattttcac
    42361 ttgacaacga acggctctat cgtagcgaag aaagtgattt cggatgacag cttgtgttct
    42421 gccttcaaga acagtgataa tattaagatt atcaaaatct tgcgcaatga aactcatctt
    42481 tcccttagtg aaggcatact catcccaaga cataatcttt ggaagccgag aaaaatcatg
    42541 ctcaaagtga aagtcattga gcttgcgaat gacagttgaa gttgaaatgg ccagctgatg
    42601 ggcaatatca gtcatagaaa ttttttcaat taacttttga gcaatttttt ggttgatgat
    42661 acgagggatt tggtgatttt tctttaccag gggagtctca gcaaccatca tttttgaaca
    42721 gtgatagcac ttgaaacggc g
//
LOCUS       DAVBIC010000013        40091 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.013, whole genome shotgun sequence.
ACCESSION   DAVBIC010000013 DAVBIC010000000
VERSION     DAVBIC010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 40091)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40091)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40091
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.013"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            276..590
                     /locus_tag="VQ664_000655"
     CDS             276..590
                     /locus_tag="VQ664_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2788863.1"
                     /translation="MWVLGFILFLIFFYSNDSKKIKKLEKKIKRLERKEKGNAEMSRL
                     LQEMIGKEPIITGVYIGPDNWEVVDVDEEWVKLRRVDNTGKEKFKLQRIEDIQTVEFD
                     GE"
     gene            600..806
                     /locus_tag="VQ664_000656"
     CDS             600..806
                     /locus_tag="VQ664_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2788864.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            806..1003
                     /locus_tag="VQ664_000657"
     CDS             806..1003
                     /locus_tag="VQ664_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2788865.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNPYQSDQFVWVYFA
                     LIPVIEWIEKKSKNLASEKGE"
     gene            1059..1739
                     /locus_tag="VQ664_000658"
     CDS             1059..1739
                     /locus_tag="VQ664_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HET2788866.1"
                     /translation="MGMFVGMFKARVESHEIILDVKALMPWISAICLLIGFISMFLTF
                     NFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAFNITGVVIPLAIFISLSEV
                     IILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLEFFATPKDVLNYINSYDEG
                     ERQANLEQSFRILFQLHQYVLPALYIFLIILSFLTGEIQLLAFLLVGAIHVYINVMQL
                     PMVKRYFK"
     gene            1751..2392
                     /locus_tag="VQ664_000659"
     CDS             1751..2392
                     /locus_tag="VQ664_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2788867.1"
                     /translation="MKLLKNLGWFLLALLSFFFIYGFIQGLATASLALGASPYAVTLL
                     YVVLAGVYVYGIYKWYQKAPVYIEKSGFNRFIWLPALVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYISRKGLVYSISLHALNNLVGFLMILML"
     gene            2410..2640
                     /locus_tag="VQ664_000660"
     CDS             2410..2640
                     /locus_tag="VQ664_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2788868.1"
                     /translation="MKRVILLAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
     gene            2676..2756
                     /locus_tag="VQ664_000661"
                     /pseudo
     CDS             2676..2756
                     /locus_tag="VQ664_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            2992..4755
                     /gene="aspS"
                     /locus_tag="VQ664_000662"
     CDS             2992..4755
                     /gene="aspS"
                     /locus_tag="VQ664_000662"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HET2788869.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEKEIQDITEGLIARVMKETKGIEVTLPFPRMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEAPAVKAIVVKGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALALEDKDLVLFVADT
                     LEVVNATLGTLRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSTEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETNKTN"
     gene            4733..5674
                     /locus_tag="VQ664_000663"
     CDS             4733..5674
                     /locus_tag="VQ664_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HET2788870.1"
                     /translation="MKQTKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINSLFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(5794..5874)
                     /locus_tag="VQ664_000664"
                     /pseudo
     CDS             complement(5794..5874)
                     /locus_tag="VQ664_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(6010..6996)
                     /locus_tag="VQ664_000665"
     CDS             complement(6010..6996)
                     /locus_tag="VQ664_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET2788871.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
     gene            complement(7006..7806)
                     /locus_tag="VQ664_000666"
     CDS             complement(7006..7806)
                     /locus_tag="VQ664_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HET2788872.1"
                     /translation="MLPYPFSYFSSIWGFRKPLSKRFELNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTNEVVQDLSEHATIVDGTLTYTGTASQAPSVVIG
                     PSQIKELPKDLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRIYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            complement(8067..8909)
                     /locus_tag="VQ664_000667"
     CDS             complement(8067..8909)
                     /locus_tag="VQ664_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2788873.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            complement(8911..10203)
                     /locus_tag="VQ664_000668"
     CDS             complement(8911..10203)
                     /locus_tag="VQ664_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2788874.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGNKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            complement(10314..11585)
                     /locus_tag="VQ664_000669"
     CDS             complement(10314..11585)
                     /locus_tag="VQ664_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET2788875.1"
                     /translation="MSSKFMKSTAVLGTATLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKVTLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIVGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            12135..13652
                     /gene="malQ"
                     /locus_tag="VQ664_000670"
     CDS             12135..13652
                     /gene="malQ"
                     /locus_tag="VQ664_000670"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HET2788876.1"
                     /translation="MKKRQSGVLMHISSLPGAYGIGSFGQSAYDFVDFLVRTKQRYWQ
                     ILPLGATSYGDSPYQSFSAFAGNTHFIDLDILVEQGLLEASDLEGVDFGSDASEVDYA
                     KIYYARRPLLEKAVKRFFEVGDVKDFEKFAQDNQSWLELFAEYMAIKEYFDNLAWTEW
                     PDADARARKASALESYREQLADKLVYHRVTQYFFFQQWLKLKAYANDNHIEIVGDMPI
                     YVAEDSSDMWANPHLFKTDVNGKATCIAGCPPDEFSVTGQLWGNPIYDWEAMDKDGYK
                     WWIERLRESFKIYDIVRIDHFRGFESYWEIPAGSDTAAPGEWVKGPGYKLFAAVKEEL
                     GELNIIAEDLGFMTDEVIELRERTGFPGMKILQFAFNPEDESIDSPHLAPANSVMYTG
                     THDNNTVLGWYRNEIDDATREYMARYTNRKEYETVVHAMLRTVFSSVSFMAIATMQDL
                     LELDEAARMNFPSTLGGNWSWRMTEDQLTPAVEEGLLDLTTIYRRINENLVDLKK"
     gene            13678..15936
                     /locus_tag="VQ664_000671"
     CDS             13678..15936
                     /locus_tag="VQ664_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan phosphorylase"
                     /protein_id="HET2788877.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVRSSR
                     SYQVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIDLDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINPNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGEENIYIFGEDSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(16980..17552)
                     /locus_tag="VQ664_000672"
     CDS             complement(16980..17552)
                     /locus_tag="VQ664_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2788878.1"
                     /translation="MNKLMKFISVFLTSIVLIVSAIPSVSAVYASEQVSQIETNMELQ
                     PVTSLTEEQINTLANEIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGIT
                     VNQMGALLDTAIALALGGTTAGLANLIKVKGKHAAKSAIRSAISRYLGSWFVNDVALE
                     FAINLLSPGTYLAQLWDKNDAIPNNGRINF"
     gene            complement(18174..19022)
                     /locus_tag="VQ664_000673"
     CDS             complement(18174..19022)
                     /locus_tag="VQ664_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HET2788879.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYDKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAN
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSQLTEITIEAEI
                     LVGKAF"
     gene            19167..19445
                     /locus_tag="VQ664_000674"
     CDS             19167..19445
                     /locus_tag="VQ664_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2788880.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            19447..21510
                     /locus_tag="VQ664_000675"
     CDS             19447..21510
                     /locus_tag="VQ664_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HET2788881.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRIRVTD
                     NQMNSRILQLIELMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLIRTEELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWFSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(21588..22844)
                     /locus_tag="VQ664_000676"
     CDS             complement(21588..22844)
                     /locus_tag="VQ664_000676"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HET2788882.1"
                     /translation="MHIFDELKERGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADENNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQDLDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            22986..25451
                     /locus_tag="VQ664_000677"
     CDS             22986..25451
                     /locus_tag="VQ664_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HET2788883.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLGFLGGMLGVGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMNKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYRMLREKGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNERFALDPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKSGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSSRARR"
     gene            25516..26427
                     /locus_tag="VQ664_000678"
     CDS             25516..26427
                     /locus_tag="VQ664_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HET2788884.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSLVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCLEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVSVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            26657..27355
                     /gene="dapD"
                     /locus_tag="VQ664_000679"
     CDS             26657..27355
                     /gene="dapD"
                     /locus_tag="VQ664_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HET2788885.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVCVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            27423..28553
                     /locus_tag="VQ664_000680"
     CDS             27423..28553
                     /locus_tag="VQ664_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HET2788886.1"
                     /translation="MLDLIQTRRALHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFTSQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDGAFGDWLPNQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            28565..29104
                     /locus_tag="VQ664_000681"
     CDS             28565..29104
                     /locus_tag="VQ664_000681"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HET2788887.1"
                     /translation="MKSELRKQVLHEMKAISQEQKQAIDQALTERILQHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKKVLTPKTYPKGRMDFVVYDPQQLVKTSFALLEPQ
                     GDLEVVDASQIDLIHVPGLAFTTDGYRIGYGGGYYDRYLEHFSGRALSTIYPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            29088..29765
                     /locus_tag="VQ664_000682"
     CDS             29088..29765
                     /locus_tag="VQ664_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HET2788888.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIVLRYATRNPYIQQLGQSYLTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILL
                     FYKGMGM"
     gene            complement(29837..30736)
                     /gene="galU"
                     /locus_tag="VQ664_000683"
     CDS             complement(29837..30736)
                     /gene="galU"
                     /locus_tag="VQ664_000683"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HET2788889.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDKTTDMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYERTHAST
                     IAVMPVPHDEVSAYGVIAPQGEGKDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEI
                     FQILENQAPGAGNEIQLTDAIDTLNKTQRVFAREFNGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            complement(30758..31774)
                     /locus_tag="VQ664_000684"
     CDS             complement(30758..31774)
                     /locus_tag="VQ664_000684"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HET2788890.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     YHTNKHYFKDVVLDENIIAYTDLAETLKDVDAILFVVPTKVTRLVAQQVAQTLDHKAI
                     IMHASKGLEPDSHKRLSTILEEEIPEQLRSDIVVVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQELFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            31986..32363
                     /locus_tag="VQ664_000685"
                     /pseudo
     CDS             31986..32363
                     /locus_tag="VQ664_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809823.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(32543..32968)
                     /locus_tag="VQ664_000686"
     CDS             complement(32543..32968)
                     /locus_tag="VQ664_000686"
                     /inference="COORDINATES: protein motif:HMM:NF025080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2788891.1"
                     /translation="MNNLSSVDSEELFQFYRERGNAENFIKERKAGFFGDKTDSSTMI
                     KNEVRMMMGCLAYNLYLFLKQLAGDEVKSLTIKRFRRLFLHIAGKYVSTARRHILKFS
                     SLYAYSKQFQALFDTICQINLILPVPYRARGQGKTCLTE"
     gene            complement(33036..33686)
                     /gene="phoU"
                     /locus_tag="VQ664_000687"
     CDS             complement(33036..33686)
                     /gene="phoU"
                     /locus_tag="VQ664_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HET2788892.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKALLALASKDKEMAEL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLADLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            complement(33701..34453)
                     /gene="pstB"
                     /locus_tag="VQ664_000688"
     CDS             complement(33701..34453)
                     /gene="pstB"
                     /locus_tag="VQ664_000688"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HET2788893.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWEEVKDDLKKSAMSLSGGQQQRLCIARA
                     LAVEPDVLLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            complement(34455..35270)
                     /gene="pstA"
                     /locus_tag="VQ664_000689"
     CDS             complement(34455..35270)
                     /gene="pstA"
                     /locus_tag="VQ664_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HET2788894.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            complement(35263..36126)
                     /gene="pstC"
                     /locus_tag="VQ664_000690"
     CDS             complement(35263..36126)
                     /gene="pstC"
                     /locus_tag="VQ664_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HET2788895.1"
                     /translation="MTKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFMANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRTFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            complement(36244..37119)
                     /locus_tag="VQ664_000691"
     CDS             complement(36244..37119)
                     /locus_tag="VQ664_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate-binding protein"
                     /protein_id="HET2788896.1"
                     /translation="MKFKKMLTLAAIGLSGFGLVACGNQSAASKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGEYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            complement(37286..38617)
                     /locus_tag="VQ664_000692"
     CDS             complement(37286..38617)
                     /locus_tag="VQ664_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HET2788897.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGQGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSALKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            complement(38618..39325)
                     /locus_tag="VQ664_000693"
     CDS             complement(38618..39325)
                     /locus_tag="VQ664_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2788898.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            complement(39409..39894)
                     /locus_tag="VQ664_000694"
     CDS             complement(39409..39894)
                     /locus_tag="VQ664_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HET2788899.1"
                     /translation="MAPTDKEDLIRTLELAPHVEGGYFRQTKKASDTINLAGKGRALY
                     TSIYFLLEETNPSHFHRLTADEIWYFHAGSPLTVHMITADGHYEAVTLGLDISKGQQL
                     HYCVPKGTIWGSTVDKDYALVSCLVAPGFEFEDFELFERVDLLATYPEHKEMIERLTR
                     Y"
     gene            39880..40091
                     /locus_tag="VQ664_000695"
                     /pseudo
     CDS             39880..40091
                     /locus_tag="VQ664_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
BASE COUNT        11758 a         7533 c         8631 g        12169 t
ORIGIN      
        1 gatagaactg acgaagtcag ctcaaaacat ggttttgagg ttgtagatga aactgacgaa
       61 gtcagtaacc atacctacgg caaggtgaag ctgacgtggt ttgaagagat tttagaagag
      121 tattaatgat agataaagtg gtcaggaacc tactcctgac ctttttcttt tgcaaaatga
      181 caaaaatcat aatttttttg acaactatac ttgtcaaaaa gaaaaagatg tgttacaatg
      241 taagcaagtt aagagaaaag aagaaaggag ctatgatgtg ggtactaggg tttatactat
      301 ttctgatttt cttttattct aatgattcta aaaaaatcaa gaaactagag aagaaaatca
      361 aaagacttga gcgaaaagag aaaggaaatg cagaaatgtc gagattatta caagaaatga
      421 ttggaaagga accaattata acgggagtgt atattgggcc agataactgg gaagttgtgg
      481 atgttgatga ggaatgggta aagctacgac gtgtagataa tacgggaaaa gaaaaattca
      541 agttgcaacg tattgaggat atccaaaccg ttgaatttga cggagagtag gtgtgtaaca
      601 tgcaactaaa aaatcgtcta aaagagcttc gagctcgcga tggtctcaat caaaccgacc
      661 tagccaaact ggcaggggtt tccagacaga ccattagcct actagaacgg gatgagtaca
      721 ccccatccat tatcattgcc ctgaaaatat ctcaaatttt caacgaaaca gtcgaatcgg
      781 tatttcgttt ggaggaggac gagtgatgaa caagtataaa gtgatttatt atgtagtggt
      841 catagcttta ttagtcagcg tatttctact gattgggatg gacctaagct ggtttaatcc
      901 ctatcaaagc gaccaatttg tttgggtcta ctttgctctc atcccagtaa ttgaatggat
      961 tgaaaagaaa tccaaaaatc tagcaagtga aaaaggagaa tgaatatgaa aaagaaacgt
     1021 agattgttat ttttgatgtc tattgtcttg gggggttctt gggcatgttt gtagggatgt
     1081 ttaaggcacg tgtcgaatcc cacgaaatta ttttagatgt aaaagccttg atgccatgga
     1141 tatcagctat ttgtttactg ataggtttca ttagtatgtt tttgactttc aatttcttaa
     1201 agaaaagcag aaaatttcat tccttgtatc aagaggaaat ggatgacgat ctgaatgaaa
     1261 cctattatgt gcaaatgtat cggaatcttg agtttggaac cattgctttt aatattacag
     1321 gtgtagtgat tccattggct atttttattt cattaagtga ggtgattata ttgcatacaa
     1381 accctcaaac atttttcctt tctttcttac tctttgtggt attcttagtc gctcaaaaat
     1441 ctctttttaa aaccattgcg attgttcgtc agtttgattt ggaatttttc gctacaccaa
     1501 aggatgtctt gaactatata aattcttatg atgaagggga gcgtcaggct aatttggaac
     1561 agagttttcg aattttattc caattacacc aatatgtctt accagcctta tatatttttc
     1621 ttattatcct ttctttcttg acaggagaga ttcagttact agctttcttg cttgtaggag
     1681 ccatccatgt ttatatcaat gtgatgcagt tacctatggt aaaacgttat ttcaaataaa
     1741 ggagttatct atgaaattac ttaaaaacct tggctggttt cttctagccc ttctatcctt
     1801 tttctttatc tatggcttta ttcaggggct cgcgactgcg tcgcttgctt taggcgcttc
     1861 accctatgct gttactctac tctatgtggt cttggctgga gtatatgtgt acggcattta
     1921 caaatggtat cagaaagctc ctgtttatat tgagaagagc ggctttaacc gatttatttg
     1981 gcttcctgcc ttggtttggt tcttatctct ggtcgttcaa ttcttcttgc cagatgatcc
     2041 ttcagtaaat cagcaaatag cgacagactt gaccttgtct caaccacttt tctcattctt
     2101 tgctgtggtt atttttgctc ctttgacgga agagattgtt tttagaggga tgttagcacg
     2161 ctatctcttt cctaagcagg acaatagtaa acgaaccctg atttttcttc tggtatctag
     2221 tcttctattt gccttgattc attttccagg tgatgtgcaa caattttttg tctattttag
     2281 ccttggtttt agtttgggtt tggcttacat tagcagaaaa ggtctggtct acagtatttc
     2341 tcttcacgct ttgaataatt tagtcggctt tttgatgatt ctcatgctat aatagagtca
     2401 ggaggtcaca tgaaacgagt aattttatta gcagtgattc aggcagtcgt tctatttttc
     2461 atcattggag cgctagctta tgccttcaaa ggcgatttct tctataacta tctagcagtt
     2521 gtctttgctc ctattgcagg tgtactgcgt tttgggacgg cttacataac ggaaattgtc
     2581 ttgcctcgaa aggcagccga aatcgctgaa aagcgtaaag caggcaaaaa ttcaaaataa
     2641 aagagtccgg tgaagttcat cggatttttg tattatactc aatgaaaatc aaagtgcaaa
     2701 ctaggaagct agccgcaggt tgctcaaaac actgttttga ggttgtggat agaactgacg
     2761 aagtcagctc aaaacatggt tttgaggttg tagatgaaac tgacgaagtc agtaacaata
     2821 cctacggtaa ggcgacgctg acgtggtttg aagagatttt cgaagagtat tagcgctaat
     2881 ttttagggct ttcacctgac ttttaaagac tggcaaactt ttctgatgat tttcatgaag
     2941 agcctgcgct tttatggtaa aatagtaaca gaataaaaga ggagagaaat aatgaaacgt
     3001 agtatgtatg ctggtcgtgt tcgtgaggaa cacatcggac aagaaataac cttgaaagga
     3061 tgggttggcc gtcgtcgtga ccttggtggt ttgatcttta tcgatcttcg tgaccgtgaa
     3121 ggaatcatgc agttggttat caaccctgaa aaagtatctg cagaggttat ggcaacagct
     3181 gaaagccttc gtagcgaatt tgttattgag gtgactggtc aggtcgctgc gcgtgagcaa
     3241 gccaatgata agttgccaac tggtgcggtt gagttaaacg tgacagctct tattgtgctt
     3301 aacacagcta agacaacacc atttgagatt aaggatggca ttgaggcaaa tgacgataca
     3361 cgtttgcgtt accgttacct tgaccttcgt cgtccagaaa tgttggaaaa tcttaaactt
     3421 cgtgccaagg tgacccactc tatccgcaac tatttggatg agttggagtt tatcgacgtg
     3481 gagacaccat tcctttctaa gtcaacgcct gaaggggcgc gtgattattt agtgccgtct
     3541 cgtgttaata aggggcattt ttacgctctt cctcaaagtc cacaaatcac gaaacagctc
     3601 ttgatgaatg ctggttttga ccgttactac caaatcgtta aatgtttccg tgacgaggac
     3661 ttgcgtggag accgccagcc tgaatttact caggtcgact tggaaacgtc cttccttact
     3721 gagaaagaaa tccaagatat tacagaaggc ttgatcgcgc gcgtgatgaa ggaaacaaaa
     3781 ggcatcgaag taacgctacc gttccctcgt atgaaatacg atgatgctat ggctctttac
     3841 ggttctgaca agccagatac tcgttttgac atgttgcttc aggacttgac agaagtggtc
     3901 aaaggtgtag actttaaagt cttttcagaa gcacctgctg taaaagcgat tgtggtcaaa
     3961 ggagctgcgg acaactattc acgtaaagac atcgacaaga tgacggaagt agccaaacag
     4021 tatggtgcca aaggtcttgc ttgggtcaag gtggttgatg gagaattaaa cggaccagtt
     4081 gccaagttct tgactggtat ccaagaagaa ttgacaacag cgcttgctct tgaagataag
     4141 gacttggttc tctttgtggc ggatacgctt gaagtggtta atgcaacact gggtaccctt
     4201 cgtggacgta ttgctaaaga gcttggcttg attgataatg ataagttcaa cttcctttgg
     4261 gtggttgact ggccgatgtt tgaatggtct gaagaagaag gccgctacat gagcgcccac
     4321 catccattca cacttccaca ggaagagact gctcacgaat tagaaggtga tttggctaag
     4381 gttcgtgcca ttgcttacga tatcgtcttg aacggttatg agcttggtgg tggtagcctt
     4441 cgtatcaacc aaaaagacct tcaagaacgc atgttcaagg ctcttggttt ctcaactgaa
     4501 gaagccaatg accagtttgg tttccttctt gaagccatgg actatggttt cccaccgcac
     4561 ggtggtttgg ctatcgggct tgaccgtttt gtcatgttgc ttgctggaga agaaaatatc
     4621 cgtgaagtca ttgcctttcc taagaacaac aaggcaactg acccaatgac acaagctcca
     4681 tcaacagtcg ctctcaaaca actagaggaa ctcagcttac aagtagaaga agatgaaaca
     4741 aacaaaacga attaagcggt ggcgctatta tctgcgccgc tttgcttatc agataaaaat
     4801 tttacgtgtc ttacaaagta tctctcgaga aaagtatgat gagaagattt cggcctctct
     4861 ggtctatggt tttttatcag cagtagcagt taatttcttt ttccaaccag ggcatgtgta
     4921 ttcgagtggt gcaacaggtc tggcacagat tatctctgcc ttgagtaatc actggtttgg
     4981 ttttcatatt ccgatttcgc taagcttcta cgccattaac ttccctttga tggtcttagc
     5041 ttggtatcag attggccata agttcaccgt ctttaccttt atcacggtat ctatgagttc
     5101 cttctttatc cagtttgtcc ctgtggcaac cttgacggag gatcccatta tcaattccct
     5161 ttttgggggt gttgttatgg gtttggggat tggttttgct cttcgaaaca atatctccag
     5221 tggtgggacg gatatcgtca gcctgactat tcgtaagaaa acgggtaaga atgtcggtag
     5281 tatttctttc ttggtaaatg gaactatcat gctgatagca ggtttgacct ttggttggaa
     5341 atacgctctt tattctatga ttaccatctt tgtctctagc cgtgtgacag acgcagtctt
     5401 tactaagcaa aagcgtatgc aggccatgat tgtgacaaat catccagaga aggtaattga
     5461 aaaaatccat aaaaaattgc accgcggagc aaccatgatc cacgatgcag aaggaaccta
     5521 taatcacgag agaaaggcag ttttaatcac tgtcattaca cgtgcagagt ttaatgaatt
     5581 taaacagatt atgacacaag tggatccaag ctcctttgtc tctgtctcgg aaaatgttca
     5641 tattctagga agatttgttg agatagataa ttagtgatta atactcttcg aaaatctctt
     5701 caaaccacgt cagcttcacc ttgccgtata tatgttactg acttcgtcag ttctatctgc
     5761 aacctcaaaa ccatgttttg agctgacttc gtcagtttca tctacaacct caaaaccatg
     5821 ttttgagcaa cctgcggcta gcttcctagt ttgcactttg attttcattg agtataaaaa
     5881 gatcttggga aaagactcaa tttcagtaga aaaggaagta aatcttccca cattaaaacg
     5941 catagtatca agttttttca atacctgata gtatgcgttt ttgcttttaa cgactttttg
     6001 cccagtctct tatttttcga taattttgtg ggcgatcaat tgacggtaac aaatttgttt
     6061 attgttttta ttatcattaa taatctggag aatagtttca agggaaacac gaccaagctc
     6121 taaactattg atatcgacat aggctgccaa gttgagcttg ggattaaccg agtcaaagct
     6181 gagaacaggg acatccagct ggtgtttggc aatatagtta caaacgcctt cagctaggag
     6241 gctatcggtt gtgatgatag catcaatttg tggatcgtgc ttgaataatc gcttgctaaa
     6301 tttatagccc ttttcttcca gaaactcgtc ggcaaagtag atgcgattgt tgtcagtggt
     6361 aagtttgtaa tgtttaagcg cctgttcata gcctgttaaa cggtctttgg tcacgaagag
     6421 ctttttactt cctccgataa aggcaatgcg tttgcagcct tttttgatga aatattcagt
     6481 cgcatcaaaa ccagcttgaa cattgtcgtt gtcgacaagt gggatgaaag gagatagaga
     6541 tttacctaag ataaggaagg ggaactgttc ttctgcgacg agttttacga gagggtcttc
     6601 ttcttgggca tagagaaaga ttagcccatc tacacgcttg ccgtagacca tttgtgaaat
     6661 agcgttgaga cgctccttct catctttccc tgttgctatc tgaatggcat agtggttttc
     6721 agatgcgact tgagagatgc cacgtagaac cgatggaaag aaaggattct ggtagaaggc
     6781 gtctgagtca tcaggaagaa ctaatccgat aacctgagta tagctgctta ccaagctacg
     6841 agcgttgagg tttgggtggt agttgagttc cttcatagct ttgcgaacgc gtttttttgt
     6901 ttcgtcgcta atggttgatt tattttgaat aacacgggtt acggttgaag gcgaaacacc
     6961 agcagccttg gccacgtctt taatcgtaac gggcataaaa atctcctatt tatggtaatt
     7021 tggatcacgg aaatgtgttt tataaaagat agtgaccaga tacagaacaa aaagaatatt
     7081 ttgtacagta atcagggttg tcatattttg gccaaataat cccaaaataa gtgtaatcag
     7141 agtcggcaat cctaaacagt tcaagataaa gtgatagcac tctttaaagg ttctaaatga
     7201 aaagaggcgt gatttcttag tgatataaag gagaagacta gctcctagag agacgataaa
     7261 gaaattcaaa ccaaagagga agctcgcacc gagaactagg aagaggctga tatagatacg
     7321 attttgttgg taccagtctt tagaaattgc ttgggtcaag ctgtctttgc ttttgaaact
     7381 ctcagtctga atggctcggt aagagatgcg ggtcagttcc ttgctttcct tgctgatgac
     7441 tagttcattt gtatcgaaat gcagttgcaa gtccttaggt aattccttga tttgacttgg
     7501 accaatcaca acagaagggg cttgactagc tgttccagta taagttaatg tgccatcgac
     7561 aattgtagca tgttcagaga gatcctggac aacctcattt gtcagaggtt catagacatt
     7621 atcgataaaa gtttctagcg gataggtctc ctgggagctg ttttggatag caatgggtac
     7681 catagacaag ctgataagga agatactggt aaagagaagt tgaaaccagt tgagctcgaa
     7741 acgtttggac aggggcttac gaaaccccca aatacttgaa aaataggaaa atggatatgg
     7801 aagcataggt atctttctaa aaggtgtttt ctatatgagt attattatat agagaaatgc
     7861 gctttatttc aagtctagga gaaaaattgc ttgctacaag gatattattt acagtgacaa
     7921 ttgctaataa tcaatgaaaa tcaaagtgca aaccaggaag ctagctgcag gttgctcaaa
     7981 gcacaacttt gaggttggag ataaagctga cgtggtttga agagattttc gaagagtata
     8041 aaatgaaaaa gggtggcggg gataaattat cccttgtcgc caccacttgt aagtcctgaa
     8101 acaaagttct tttgtagaaa gaagaagaga atacagattg gaagggcgat gaggatagca
     8161 cctgctgaga agtaggcaat cttcaagttt ttcgcattgt taacgaaggt ttggagacct
     8221 acggcaacag taaagtattc tttctcacga agcaagaaac tagagaggat gtagtccccg
     8281 aaaggtccca tgaaggccca gagagcttgt acggcaacca ttgggcgaac aagtggtaga
     8341 acaatttgcc agaagcggcg gaagtgtcct gcaccgtcta gttttgcaga ttcgtctaaa
     8401 gacattggca ctgtatcgaa gtagcctttc atgagccaag cattcatcgg gataccacca
     8461 ccaacgtaga ggaagatgag gaaccagttg tggttaaggg cgttcaacat aagcgccata
     8521 acgaagaagg ctgtcaaagc ggccatagtt ggcaccattt ggatgatcaa gaagaagacc
     8581 aaactttgtt tacgagccaa gaagttgtaa cggctgtaag cataaccagc aagtacgatg
     8641 atacttgttt gaacagccat ggtaattaag gcgataatca aagtgttgag gtaccaagta
     8701 ccgtacaagg tttcagtgaa gaggccttta aagttatcaa aattgaggtc gatattagta
     8761 tctagtttaa aggctgagac gttacctgct ttaaaggctg acataatggt aatcaacagt
     8821 ggatagataa ttacaattga tagaccaatc aggtaaaggt aagtaaggct ttgagtcagt
     8881 ctacgtttga gtttaattga gttattcatc ttagacgtcc tccatatcaa atgcgtgtag
     8941 tttcttgaat gcgatcatag agattgagat gacaatgata gagataatca aggtaacagc
     9001 tgccgccatt gagtattgag gagatgtacc tgttgtcaaa cggtagatcc atgagatcaa
     9061 gatatcggtt gaaccagctc cacctccgac actaccaggt cctccaccat tgaagaggta
     9121 catgatagag aagttgttaa agttgaaggt gtattggcta atcaaagtag gtgccgcaac
     9181 agccaaaatc attgggaaag tgatgttgcg gaatttttgc caagcgttgg caccgtcaat
     9241 ataagctgct tcgtaaaggt cgttaggaat agattgcaag atacccaaag tcaaaacgta
     9301 gatgtatggg aatccgagcc aaccttgcat cataatcaag gcaatcttag tccaagttgg
     9361 gtctgttttc caaggaataa gagctccatc aaggaaagga aggaatttag ccaagattgg
     9421 caatacttga gtgttgatag caccgacact atcgttaaac atgtttgaga atgtcaagat
     9481 agtgatgaag gctgggacag cccaaggaag aaggaaaata acaccaaaga tacgttttcc
     9541 tttgataaat ggttggttgg caatgatagc tgtgaagata ccaattacga tttgtaaagt
     9601 agaagctgcc aaagcccaaa tgatagtcca agaaagaaca gaaccaaagg cagaacggaa
     9661 ggtactcaag ctccaaatgt ttgtaaagtt ggtcaaacca acccagtcca acaacttgtt
     9721 tggtggcaag tgttggaagt cgtagttggt aaaggcgatc atcaaggtta cgataactgg
     9781 gaagataatc gcgaaggtca tggcaacata agatggaatg atcaagaggt aagggaagcc
     9841 attttcataa atccctttga tcatgtcttt gagtgtgcgt ggaactggaa ttccattgtt
     9901 aatgcgtttt gcaatcgtat gtgcatcttt gatatttgag aaataaaaga gtacataaac
     9961 gattacaaag attagatgga aggcaccacg aatcagcata aagagggaat tatcacgacc
    10021 tggtttgtta ccaagagtga tgaggttgct caattcaggg gttgcaagtg ctaggaagta
    10081 aaggacaaat acgatggtta caccaaggaa gataaaacct ttggcttttt gtttattgta
    10141 aatctgtcct aacccaggaa tgatagacag cagggctgct ttactaggtt gttgcttttc
    10201 catattaact cctttcatag gatactactt ttttataaga aagctaaatt atttgtgtct
    10261 ctattgataa attcaaaggg ggatttgatt tccacccccc ttgaacaaat tttttattca
    10321 ccaaattttt gtttgattgt ttctttgatc aatgttacag catcgttagc agctgtttta
    10381 gcatcttttt gaccacttac agcatcaaag agcatatttt tcgctggatc ccaaactgca
    10441 gacatttgag agatgtttgg cagtggttga gtgttcttga actgtttgat aacagctgtt
    10501 gtcaactcat cgtttttacc ttcagcgtat gaacgagcct cagtattagc tgggatttcg
    10561 ttagtcttat catataatac tttttgttgt tcagttgcaa caaggaagtc tacaaatttt
    10621 tgagaagctt caaggttctt aacggcttga ggaatgaccc aagctttacc accaccgaat
    10681 gcagcatatt cttttccatt tggaagagtt gggatagttg caactccgta gtttacttta
    10741 gcatctttaa aggcttgagc tttccaaggt ccgtcgatga tagcagctgt tttaccttct
    10801 tggaattgag tttggattaa gtttccagca ccttctgtat cttgcatacc tttaggccat
    10861 ttttcgtacc aagatttagc gtaattgata cctacgatag aaccgtcgtt tgcaagaccg
    10921 atgtctttag cgtctttacc gttttggcca aagacgtaag caccgttacc ggcaagaagt
    10981 ccatatgtat agtagaagtt tgtccagtca gctaggaagg cagtagtttt accatcttca
    11041 ccagcgaatg cgtatttgct atctttagca aggttttcca agtcagcaaa tgtttttgga
    11101 gcatctttca ccaagtcttt gttgtagtac ataacaagtg actcgataac ggcaggagca
    11161 ccgtaaactt taccattagc agctgttaca agagatttag ttgtgtcgtc tgttttagca
    11221 ccatcgctca atttcacttc tgaaagttgt ccgtcagaac caaggctacc tacacggtcg
    11281 tatggagcca tcataacatc agggacatta ccagattggt tgtcaagaga aagtttatca
    11341 agacctccta gagcatcacc agttttaaga gtgactttta ctccagcttc tttttcataa
    11401 gctttagcaa cctcttcaat atagctctta tatccctcgt ctacatatac agtgagttct
    11461 ttgacttcag atgaaccaga atcagcaggc ttatcagcag ttttgcttcc gcaagctacc
    11521 aaaagcaagc tagcaagtgt agcagttcca agcaccgcag tgctcttcat aaatttagat
    11581 gacatagtgt attcctccta aagaatagca agttttattg ataaggaaac gcaaacgttt
    11641 tcctttatga gcttagtata gcacaaatag aaaacggttg caagtatttt ttgtaaaaat
    11701 tttaaaaaat ttttaagctt gatttgatag cataattttg cattttaata gaagaaaagt
    11761 atgaaataga taagaataca gtatttttaa taaaaatata tggaatctgt ctaaagaggg
    11821 aaatcaggag gggctacctc cctgtttcta atctatatct attttctata gacgtttgtg
    11881 ctttgttaca tataaattca agctccctaa ggaggtttta tactttgtag actgtctcgt
    11941 gagagtcaaa ccttaggatt agatagtttt aagttatctt tgctaaaatg agttagtttc
    12001 cttaaaaata atcaaaaaag ttttttaaaa acgcttgcaa ttatgcttga aaaggagtat
    12061 acttataagt aacgcaaacg tttgcgtctg caaaatacgc aacgttccat tattttaaca
    12121 cacgaggtgc tattatgaaa aaacgtcaaa gtggtgtgtt gatgcacatc tcttctcttc
    12181 caggagctta cggaatcgga tcatttggtc aaagtgctta cgacttcgtt gatttcttgg
    12241 tccgtacaaa acaacgttac tggcaaatcc ttccattagg agcaactagt tacggggatt
    12301 ctccttacca atctttctca gccttcgcag gaaacactca ttttatcgat ttagatatct
    12361 tggtggagca aggtttgttg gaagcaagtg accttgaagg agttgacttt ggtagcgatg
    12421 cgtctgaagt tgactatgct aaaatctact atgcacgtcg tcctctttta gaaaaagcgg
    12481 tgaaacgttt ctttgaagtc ggagatgtta aagattttga gaaatttgct caagacaacc
    12541 aatcatggct tgagctcttt gctgagtata tggctatcaa agagtatttt gacaatcttg
    12601 cttggactga atggccagat gcagatgctc gtgctcgtaa agcttcagca cttgaaagct
    12661 atcgtgagca attggcagac aagttggttt accaccgtgt gactcaatac ttcttcttcc
    12721 aacaatggtt gaaattgaaa gcttacgcta acgacaacca catcgaaatc gttggggaca
    12781 tgccaatcta cgtagcggaa gattcaagtg atatgtgggc aaatccacat ctcttcaaaa
    12841 cagatgtcaa tggtaaggct acttgtatcg caggatgccc accagatgag ttttctgtaa
    12901 ctggtcagct ttggggtaac ccaatctatg actgggaagc aatggacaaa gacggctaca
    12961 aatggtggat tgaacgcttg cgtgaaagct tcaaaatcta cgatatcgtt cgtatcgacc
    13021 acttccgtgg cttcgaatct tactgggaaa tccctgctgg ttccgataca gcagcacctg
    13081 gtgagtgggt gaaaggtcca ggctacaagc tttttgcagc cgttaaggaa gaacttggtg
    13141 agctaaacat catcgcagaa gaccttggct tcatgacaga tgaagtgatc gaattgcgtg
    13201 aacgtactgg cttcccagga atgaagattc ttcaatttgc cttcaaccca gaagacgaaa
    13261 gcattgatag cccacacttg gcacctgcta actcagttat gtacacagga acacacgata
    13321 acaatacggt tcttggttgg taccgtaatg agattgatga tgcgactcgt gagtacatgg
    13381 ctcgttacac gaaccgtaaa gaatacgaaa cagtggtaca cgctatgctt cgtacagtat
    13441 tttcatcagt tagctttatg gcaattgcaa ctatgcaaga tttactagaa ttggatgagg
    13501 cagctcgtat gaacttccca tctacccttg gtggaaactg gtcttggcgt atgactgaag
    13561 atcaattgac accagctgtc gaggaaggtt tgcttgactt gacaacaatt tatcgccgaa
    13621 ttaatgaaaa tttggtagat ttaaagaaat aagacaataa tcaggagaca actaaacatg
    13681 ttatcactac aagaatttgt acaaaatcgt tacaataaaa ccattgcaga atgtagcaat
    13741 gaagagcttt accttgctct tcttaactac agcaagcttg caagcagcca aaaaccagtc
    13801 aacactggta agaaaaaagt ttactacatc tcagctgagt tcttgattgg taaactcttg
    13861 tcaaacaact tgattaacct tggtctttac gacgatgtta aaaaagaact tgcagctgca
    13921 ggtaaagact tgatcgaagt tgaagaagtt gaattggaac catctcttgg taatggtggt
    13981 ttgggacgtt tggctgcctg ctttatcgac tcaattgcta ctcttggttt gaatggtgac
    14041 ggtgttggtc ttaactacca ctttggtctt ttccaacaag ttcttaaaaa caaccaacaa
    14101 gaaacaattc caaatgcatg gttgacagag caaaactggt tggttcgctc aagccgtagc
    14161 taccaagtac catttgcaga ctttactttg acatcaactc tttacgatat tgatgttact
    14221 ggttatgaaa cagcgactaa aaaccgcttg cgtttgtttg acttggattc agttgattct
    14281 tctattatta aagatggtat caactttgac aagacagata tcgctcgcaa cttaactctc
    14341 ttcctttacc cagatgatag tgaccgtcaa ggtgaattgc tccgtatctt ccaacaatac
    14401 ttcatggttt caaacggtgc gcaattgatc atcgacgaag caatcgaaaa aggaagcaac
    14461 ttgcatgacc ttgctgacta cgcagttgtc caaatcaacg atactcaccc atcaatggtg
    14521 attcctgaat tgattcgtct tttgactgca cgtggtatcg atcttgacga agcaatctca
    14581 attgttcgta gcatgactgc ctacactaac cacacaatcc ttgctgaagc gcttgaaaaa
    14641 tggcctcttg aattcttgca agaagtggtt cctcacttgg taccaatcat cgaagaattg
    14701 gaccgtcgtg tgaaggcaga gtacaaagat ccagctgttc aaatcatcga tgagagcgga
    14761 cgtgttcaca tggctcacat ggatatccac tacggataca gtgttaacgg ggttgcagca
    14821 ctccatactg aaatcttgaa aaattctgag ttgaaagcct tctacgacct ttacccagaa
    14881 aagttcaaca acaaaacaaa cggtatcact ttccgtcgtt ggcttatgca tgctaaccca
    14941 agattgtctc actacttgga tgagattctt ggagatggtt ggcaccatga agcagatgag
    15001 cttgaaaaac tgttgtctta tgaagacaaa gcagctgtca aagaaaaatt ggaaagcatc
    15061 aaggctcaca acaaacgtaa attggctcgt cacttgaaag aacaccaagg tgtggaaatc
    15121 aatccaaatt ctatctttga tatccaaatc aaacgtcttc acgagtacaa acgccaacaa
    15181 atgaacgctt tgtacgtgat ccacaaatac cttgacatca aagctggtaa catccctgct
    15241 cgtccaatca caatcttctt tggtggtaaa gcagctccag cctacacaat cgctcaagat
    15301 atcattcact tgatcctttg catgtcagaa gttattgcta acgatccagc agtagctcca
    15361 cacttgcaag tagttatggt tgaaaactac aacgttactg cagcaagctt ccttatccca
    15421 gcatgtgata tctcagaaca aatctcactt gcttctaaag aagcttcagg tactggtaac
    15481 atgaaattca tgttgaacgg agctttgaca cttggtacta tggacggtgc taacgtggaa
    15541 atcgctgagt tggttggaga agaaaacatc tacatcttcg gtgaagattc agaaactgtt
    15601 atcgaccttt acgcaaaagc agcttacaaa tcaagcgaat tctacgctcg tgaagctatc
    15661 aaaccattgg ttgacttcat cgttagtgat gcagttcttg cagctggaaa caaagagcgc
    15721 ttggaacgtc tttacaatga attgatcaac aaagactggt tcatgactct tcttgacttg
    15781 gaagactaca tcaaagtcaa agagcaaatg cttgctgact acgaagaccg tgacgcatgg
    15841 ttggataaag tcatcgttaa catttctaaa gcaggattct tctcatctga ccgtacaatc
    15901 gctcagtata acgaagacat ctggcacttg aactaatact cttcgaaaat ctcttcaaac
    15961 cacgtcagct ttatctgcaa cctcaaagcg gtgctttgag caacctgcgg ttagcttcct
    16021 agtttactct ttgattttca ttgagtataa gatacaaatt tatactaata catcttgtaa
    16081 aaaagcgagt ttcgattgaa attcgctttt ttaatgatgt agatttgggt caatcttgtc
    16141 taaaaatagg gaaatcctag atacagtgaa ggctttaaat gctggttttt actgtcctca
    16201 gccttatatt ttttcgtagt tgattacctc atacctcttg tattcgctta cataaagtat
    16261 tataatataa ttgtaggaaa gaaggtgttt ttatgatata cacacttaaa ttggtgttgt
    16321 ttattacctt tcttgtaata agcttgttac ctgataagat ttttggaaaa aataaaaaaa
    16381 tttggaaaat agtttttgca atattgacgg cagtggcagc attgtcattt atgtactaag
    16441 ttattttaag aatgtaggga aataaaccct acattctttt tagttttttc tgttttctaa
    16501 attctattta tccaagcgct tcaacatttc ttgcttcttc gcttcaagtt ctgcacgctt
    16561 ttcttcgatt tcggcatgtt ttttctcgag ttcagaacaa cttgcaccat tgctaaattc
    16621 ttttcgccat caggagatag ggtgagtcga catgtctatt actcacccaa agcagtccta
    16681 caaagcagga attttctgtt acttttttgg aaatagtaac gtttatacag ctttgacact
    16741 tcgtatcaaa gcgccaaaca cactccgagg gatttacaga aagcagaaaa ggaatgatct
    16801 ggtataagat cattcctttt ctctcttttt ctttaagtaa ttatatacaa tgtacgacga
    16861 agtcgtcatt gcaatgctga tccaccacct aaaggaaact ttaaacaaca ttgataagat
    16921 aaagaatata aacaacgaaa atacgttata cccaattaat tttattgtat atctcatgat
    16981 taaaagttaa tccttccgtt gttaggaatg gcatcatttt tatcccataa ttgtgctaaa
    17041 taagtccccg gtgataataa atttatagca aattctaaag caacatcatt tacaaaccaa
    17101 ctacctagat atctagaaat tgctgaacga atagcacttt ttgctgcatg ttttcctttt
    17161 actttaatta gatttgcaag gcctgcagta gttcctccta atgctaaagc tattgcagta
    17221 tctaatagag cacccatttg attaactgta ataccttgcc aagctgctct aaatggagag
    17281 tatgtaggtg ggattgtata atcgccttgt aattgtcggt taattacttc tttgatccat
    17341 tgttgtgaga cgtctggatg aaaagattgg atttcgtttg caagtgtatt gatttgttct
    17401 tctgttagag aagtgacagg ttgaagttcc atatttgttt caatttgtga tacttgttca
    17461 gaagcgtata cagctgaaac acttggaatc gctgatacaa ttaacacaat tgacgtcaaa
    17521 aaaaccgaaa taaatttcat taatttgttc atgagctttt ctccttttta tttgtatctg
    17581 cttacatttt atcatatgct gttattatag tcaaaaaaat atgctattat gttaaaaaaa
    17641 tatttttcaa aatataaatg gacggattta ttttggattt tatttgttat tttgacctgc
    17701 ctctatattg gtaaccatga tttgtttact ctcaatcatc aagaattctc ttttcgtggt
    17761 agcgtttggg gtctggtact ggccttatat cacttactat tcattgataa gtttgttata
    17821 tcgaatcgaa aataaagatt agagctatgc ttgactgtgt acttttagga ttgattttgg
    17881 aggaagattt tgtctctatt atttattatt ttaaatttat ttattttgta taagatctat
    17941 tctttgaggc gggaaaaatc gaaatacttg atttatacgg cctatatcat atttggggta
    18001 aatgtagtat atggtattca atggttatta agagaactga tttcaactat ttccccttaa
    18061 tgtgtatgga aactataaca aaacgcataa gattaaggtt tgtgtacctg ttcttatgcg
    18121 tttttataat attgaagatt ttcggtaagt tttatacctt tgggaagtct agtttagaat
    18181 gctttcccaa ccaaaatctc tgcttcgatg gtaatctctg tcagttggct ccagtcaatc
    18241 ttgctctggt caacgtgaaa gaggagagga gtcatactga gtagggcttg gagttgttct
    18301 gctgtgatag tcttagtcag agaggcagtt tgactagata ggatggtaaa gtgttcctgg
    18361 aaatgctcct tgatatcttg gttagaatac tccttgtttg tcagctggtc ctgtactctt
    18421 tgacggattt ctttgaggtg attttcagtt gggataacct ttatcaagat accgtctttg
    18481 gataaaacgc gacgaaattc tccatagttg gcaggtgaga agatatcaag cagaatatcc
    18541 atgttagcgt cttttatagg aagtcgtgcc aagtcgccaa cgaaccaatt gactgcccag
    18601 ttgggttcac ttttagcagc gatttggact gaatctttgg agatgtcaaa ggcatagaaa
    18661 gttttttcag agtgactttc ttgtagtttg cgagaataga atccttcacc acaaccgata
    18721 tccaaaattg ttgtggtagt ttttgagctt gcaagcaagt cagatacagc atctaagata
    18781 gcttggtaaa agccggcttc taggatttgt tgacggtttt gaaaattttc cttgtcatag
    18841 ttagcagatt gcttgatttg aggtgctaga ttgacatagc caaatttcgc caagtcaaaa
    18901 gaatgacggt tgcagcactt gaaattagtc tctaacagag tcagattttc ttgacagata
    18961 ggacaggcaa aggcagtcgc agaagcaaaa cgctgaagtt tgggcttgag atttgtattc
    19021 atagtttaag tgtatcaaaa gaggcaaatg aaagcaactt taggaataag tagattcagt
    19081 agaaataaaa ctaattctcc aatttataga atgaaattgc ttttatatct aaattgctat
    19141 ataataatga taaggaggaa ataagtatgt taaaagaagt attaaccgtt gcaaaagttg
    19201 cgaaaaaatc ttcattattt ttgggtggtg tcgcatttgg tacccttggt ttgaaaatct
    19261 tagcaagtaa ggaagctaaa aaaggttatt ctaaagcttt ggctaaggct tacaagttga
    19321 aagacgagct agatgcatct gtttctgttg tgaagcaaca tggagacgat gtcttgcaag
    19381 atgccaaata tttgtacgag caagagaaaa aagaagagca attagatagc cttataggtg
    19441 aataatatgt cttttaaagt gctacataga ggataccaac atatccgact atcatcttct
    19501 ttttcactta ccttggatat tcaagactat cttcgttcct tggcgagaga tgaaaagggg
    19561 attgagtcta tccagtttta catggatcaa cagcacttta ctctacgcat aaaagaaggc
    19621 ttttctgtat tagataatgc agaagccttt ttaaaaagaa ttgataaagg gaaagtttct
    19681 gagttgatga ctcttcccat tcgtagagaa gagagtgctt attctattgt ttcaggtgca
    19741 gcggttaagc gtgtactttt tcgtagtttt gtgccgtatc ctattcgcta tatatggact
    19801 tgttatcagg ctttgggtta tattagagaa gcctatcaaa cactagcgcg taaggaacta
    19861 acgatggaag tcttggactg ttcggctatt ttattgtcct tgtttatgaa ccaatccaag
    19921 acagctagca atatcatgtt tatgcttgat ttggggaatc atttagatca gtggtccttg
    19981 aaaaaaactg caacagattt agaacagagt cttcttgcaa aagagagcga tgtattccta
    20041 gtacagggcg atacggttgt tagtatcaag agttccgatg ttcaaatagg agatgtcttg
    20101 atcttatctc aaggaaatga aattctgttt gatggacaag tagtttcagg tttaggtatg
    20161 gtcaacgaaa gttccttgac aggagagagt tttccagttg aaaaaagaga gtctgatttg
    20221 gtttgtgcaa atacagtatt agaaactgga gagttacgca ttcgtgtaac agataatcag
    20281 atgaacagcc gtattttaca gctgattgag ttgatgaaga aatctgaaga aaacaagaaa
    20341 acgaaacaac gctatttcat caagatggcg gataaagtcg tcaaatataa tttcttgggg
    20401 gctgggctga cttacctatt gacaggttct ttttctaagg ctatttcttt cctattggtc
    20461 gatttctcct gcgctttgaa aatctctact cctgtagctt atttgacagt tatcaaggaa
    20521 gggttgaacc gtgaaatggt gattaaggat ggagatgttc tggagaaata tctggaagtt
    20581 gatactttct tgtttgataa gacaggaaca atcacaacta gttatcctat agttgaaaag
    20641 gtgttacctt ttggagacta tagtgaggaa gatattctca gaatcagtgc ctgtcttgag
    20701 gaacacattt atcatcctat tgctaatgcc atcgtcaagc aagctgagat agagggaatt
    20761 gaacatgagg aaatgcatgg gaaactccaa tatatcgcaa gcaaggggat caaatctcat
    20821 atagatggcc aaccagttct tattgggaat tatgtcttga tgcaggatga gcagattcat
    20881 atcagttcag aacaaaatgc tttaattgaa gagtacaaga gtcactacaa tctcttattc
    20941 ttggcttatc aaaatgaatt gattggaatg ttctgcattc atactccttt gagaaaagaa
    21001 gcaaaaacag ccttggataa acttaaggca caggggaaaa aattgattct ggcaacagga
    21061 gacaccttga ttaggacaga ggaattagtc aaagatttgc cctttgatca ggtctataca
    21121 gacttgaaac ctgatgggaa atttgagtta gtagagaaac tgcagaaagc aggtcacact
    21181 attttgatgg ttggagatgg attgaatgac tcagcggctt taactctatc agatatcggt
    21241 gtggtgatga atgagagtgc agatatttct aagcagatga gtgatatctt attgttagat
    21301 aatcgtttgg atttcttcca agagttggat tcgttatcat catctttgca aacactcatc
    21361 aagaaaaata ttcaggatac cgttgtcgta aatagtagtt tgattggctt tggcttattt
    21421 aattggttca gtccttcaaa tctctctatc ttacataatc taacaacctt gcgcattgtc
    21481 ctgcgtagcc tgtctattaa aaatagatag atgagagtta ttaacagcaa aaaggagtta
    21541 cctttctcga ggttaactcc tttgtttata gataaatgtt gaatagttta gtaagtcaat
    21601 acaaagtatt ttttcttccc acgacggata acagtcagtt cattttctaa cttatcagcg
    21661 tcactcaaga catagtcaag gtcttggatg cggtcgccgt ttacgtagat ggctccgttt
    21721 tggacgtctt cacgggcttg gcgttttgag ttaactatac cagatgagac gagcagttcc
    21781 acgatattgt tgttttcgtc tgcctgtact tggtagtttg gcacaccacg aagtccttgt
    21841 ttgagctctt tgacagaaag gtttttgatg tttcctgcaa agagttgctc agtgatgtta
    21901 agtgcttctt tgtaggcttc ttctccgtga acaagtgtaa caacttcacg agccaagact
    21961 ttttgagcca agcgttcgtg tggcgctgct tcaaattgtt tacgaatatc ttcaatctca
    22021 tcaagtgaca agaaagtaaa gattttcaag aagcgaacag cgtcagcgtc catcacgttc
    22081 atccagaatt ggtacatttc gtatggagaa gtcttttcgg gattgagcca gacggcattt
    22141 ccttctgatt taccaaattt tttaccagtt gcatctgtga ttagtggaac agtgataacg
    22201 tgaccagtct tgtccgcctt acgacgaagc aattcggtac cagctgtcat atttccccac
    22261 tggtcagaac caccgatttg aagagtgaca ttatggtctt ggttaaggac gaagaagtcg
    22321 tacccttgca tgatttggta agcgaactca gtgtaagaaa ttcctgtttc gatccgtttt
    22381 ttaacagatt ccttactcat catgtagttg accgtgaagt actttccaat gtcacggagg
    22441 aagtcaatga agctgatgct gccaaaccag tcgtagttgt tgaccatgac agccttgttt
    22501 tcgccatttt caaagtcaag aaaacgagaa agttgtcctt ggatagactt gacccagcca
    22561 tctactgtgt cttttgtttg gagactacgt tcagcatctt tgaaggacgg atctccgatg
    22621 agacctgtag caccgccaac gagcgcataa ggtttgtgac ctgctagttg caagcgacga
    22681 cttgtcaaga ttgcgacaag gtggcctagg tgaaggctgt cagcagttgg atcgtagcca
    22741 gtataataag aaacttgacc ttcttctagg gctttacgca aagcttcttc atcagtcgtt
    22801 tgaaatatca aaccacgctc ttttagctca tcaaaaatgt gcatgtgtct tttctccttt
    22861 ttaaaattat tgtttctacc tattgtatca caaacttggg caatagccta gcagaatagg
    22921 gaagaaagtg gctattttat tgaaaatttc ccttttgtgg tataatagat aaagtgagga
    22981 aatccatgca aaatcaatta aatgaattaa aacgaaaaat gctggaattt ttccagcaaa
    23041 aacaaaaaaa taaaaaatca gctagacctg gcaagaaagg ttcaagtacc aaaaaatcta
    23101 aaaccttaga taagtcagcc attttcccag ctattttact gagtataaaa gccttattta
    23161 acttactctt tgtactcggt tttctaggag gaatgttggg agttgggatt gctttggggt
    23221 acggagtggc cttatttgac aaggttcggg tgcctcagac agaagaattg gtgaatcagg
    23281 tcaaggacat ctcttctatt tcagagatta cctattcgga cgggacggtg attgcttcca
    23341 tagagagtga tttgttgcgc acttctatct catctgagca aatttcggaa aatctgaaga
    23401 aggctatcat tgcgacagaa gatgaacact ttaaagaaca taagggtgta gtacccaagg
    23461 cggtgattcg tgcgaccttg gggaaatttg taggtttggg ttcctctagt gggggttcaa
    23521 ccttgaccca gcaactaatt aaacagcagg ttgttgggga tgcgccgacc ttggctcgta
    23581 aggcggcaga gattgtggat gctcttgcct tggaacgcgc catgaataaa gatgagattt
    23641 taacgaccta tctcaatgtg gctccctttg gccgaaataa taagggacag aatattgcag
    23701 gggctcggca agcagctgag ggaattttcg gtgtagatgc cagtcagttg actgttcctc
    23761 aagcagcatt tttagcagga cttccacaga gtcccattac ttactctcct tatgaaaata
    23821 ctggggagtt gaagagtgat gaagacctag aaattggctt aagacgggct aaggcagttc
    23881 tttacagtat gtatcgtaca ggtgcattaa gcaaagacga gtattctcag tacaaggatt
    23941 atgaccttaa acaggacttt ttaccatcgg gcacggttac aggaatttca cgagactatt
    24001 tatactttac aactttggca gaagctcaag aacgtatgta tgactatcta gctcagagag
    24061 acaatgtctc cgctaaggag ttgaaaaatg aggcaactca gaagttttat cgagatttgg
    24121 cagccaagga aattgaaaat ggtggttata agattactac taccatagat cagaaaattc
    24181 attctgccat gcaaagtgcg gttgctgatt atggctatct tttagacgat ggaacaggtc
    24241 gtgtagaagt agggaatgtc ttgatggata accaaacagg tgctattcta ggctttgtag
    24301 gtggtcgtaa ttatcaagaa aatcaaaata atcatgcctt tgatacaaaa cgttcgccag
    24361 cttctactac caagcccttg ctggcctacg gtattgctat tgaccagggc ttgatgggaa
    24421 gtgaaacgat tctatctaac tatccaacaa actttgctaa tggcaatccg attatgtatg
    24481 ctaatagcaa gggaacagga atgatgacct tgggagaagc tctgaactat tcatggaata
    24541 tccctgctta ctggacctat cgtatgctcc gtgaaaaggg tgttgatgtc aagggttata
    24601 tggaaaagat gggttacgag attcctgagt acggtattga gagcttgcca atgggtggtg
    24661 gtattgaagt cacagttgcc cagcatacca atggctatca gaccttagct aataatggag
    24721 tttatcatca gaagcatgtg atttcaaaga ttgaagcagc agatggtaga gtggtgtatg
    24781 agtatcagga taaaccggtt caagtctatt caaaagctac tgcgacgatt atgcagggat
    24841 tgctacgaga agttctatcc tctcgtgtga caacaacctt caagtctaac ctgacttctt
    24901 taaatcctac tctggctaat gcagattgga ttgggaagac tggtacaacc aaccaagacg
    24961 aaaatatgtg gctcatgctt tcgacaccta gattaaccct aggtggctgg attgggcatg
    25021 atgataatca ttcattgtca cgtagagcag gttattctaa taactctaat tacatggctc
    25081 atctggtaaa tgcgattcag caagcttccc caagcatttg ggggaacgag cgctttgctt
    25141 tagatcctag tgtagtgaaa tcggaagtct tgaaatcaac aggtcaaaaa ccagggaagg
    25201 tttctgttga aggaaaagag gtagaggtca caggttcgac tgttaccagc tattgggcta
    25261 ataagtcagg agcgccagcg acaagttatc gctttgctat tggcggaagt gatgcggatt
    25321 atcagaatgc ttggtctagt attgtgggga gtctaccaac tccatccagc tccagcagtt
    25381 caagtagtag ttctagcgat agcagtaact caagtactac acgaccttct tcttcaaggg
    25441 cgagacgata attctctaaa tgaagtggcc aatcaatgga ttgccacttt tttcctttcg
    25501 tgttacaata agggtatgaa tcagtatcag aaaaagattg ttaacggaaa aatttattcg
    25561 ctcctatccg gcttaatatg gggaatctgt ggaattttag gagagtactt ctttactcat
    25621 tatcaggtgt cttcgggctg gattacctct atgcgtttga cactggcagg gagtcttgta
    25681 ctcatttggt ctgcaataca attaaaatcg caagtgctag atatttggcg agacaagaaa
    25741 aattacctgc cctttttagc ctatgctatt ttggggattt tttcagttca gtattttttc
    25801 tatctctgtt tagaatactc aaatgctacg acagcaacta ttttacagtt tattagccct
    25861 gtctttatcc tcttttacaa tcgcttggtt tatcaaaaac gagcgtcaaa aagcgctgtt
    25921 ttctatgttt tggttgccat gctgggtgtt tgcttgatgg cgacaaaggg agatctctct
    25981 cagttatcca tgacgccgct agctcttata acaggtttgc tgagtgccat gggtgttatg
    26041 tttaatgtta tcttgcccca accttttgct aagcgttatg gttttgttcc tacggttggg
    26101 tgggggatga ttttggcagg tttgtttagc aatgtcctct cgccggttta tcagctttcc
    26161 tttactcttg atatttggag tatcttgatt tgcctcatta tcgctttctt tggaacggct
    26221 tttgcttttt tcatttccat gaaggctgtg tccttggttt ctcctttggt ggtttccgtt
    26281 atcagtgcca gtgaacctct ctcttctgct ctcttgagtg ttttgttctt aggattagta
    26341 gtggattggt ccctccttct agctatagcc ttgattattt tacccatgat atttttgtct
    26401 atagaagaag cgaaagaaag tagataaaaa gtcttttctt aattctaaaa gtgtgctata
    26461 ctagaatagt caataaaaca cggggagata gttgtgaaga gtatttttag gttgtatcgg
    26521 taggggcttg cttttaccga cagcacgttt tatctcacat ccctaaaaaa tcatacctaa
    26581 aaacagacaa aaaggtttca aatttgaggc cttttttggt agaataggta tcattataac
    26641 gaaccaggag gcacctatga ctgctacaaa aatgaacgct caagaaatta tccaatttat
    26701 cgccaatgct gaaaagaaaa ccagtgtcaa agtaaccttt gaggggcaac tcgcaactgc
    26761 tgtgcctagc tctgttgtca aactaggaaa tgtcctattc ggagactgga aggacgtggc
    26821 tccgcttctt gaaggtttgg tagaaaatca agattatgtt gtcgagcaag atgctcgtaa
    26881 ttctgcagtt cctttgctag ataagcgtgc tatcaacgct cgtatcgagc caggtgctat
    26941 tatccgtgac caggtggaaa ttggtgacaa tgctgttatc atgatgggag ctgttatcaa
    27001 tatcggtgct gaaatcggtg ctggaaccat gattgacatg ggtgccatcc ttggtggccg
    27061 tgctatcgtt ggaaaaaata gccacgttgg tgcaggtgca gttttggcag gtgtgattga
    27121 gccagctagt gctgaaccag tctgtgtcgg agacaatgtt cttatcgggg ctaatgcagt
    27181 ggttatcgaa ggagtccaaa tcggtagtgg ttcagttgtc gctgcaggag ctatcgttac
    27241 ccaagatgtc ccagaaaacg tggtagtagc aggtgttcca gctcgtatta tcaaagaaat
    27301 tgatgcccaa actcaacaaa aaacagcgct agaggatgcg cttcgtacct tgtaattgta
    27361 aaagtaaaaa agaggcggaa ccctttttcc agcctctttc tgctatatcg gaggacagat
    27421 agatgttaga tttgattcag actagacgag ctttacacca gattccagag attggcttgg
    27481 aggagttcaa gactcaggct tatttgctgg atgtgattga gaaattgact acgggcaagg
    27541 attttgttca aattcgtact tggcggacag ggattttggt ctacctgcag ggaagtcagc
    27601 cggagcgaac cattggttgg cggacagata ttgatggcct gcctatcgtc gaacaaacag
    27661 gtctaccttt tacttctcaa caccaaggtc gcatgcatgc ctgtggtcat gattttcata
    27721 tgaccattgc cttaggctgt cttgagcgcg cccttgagga gcaacccaag aataatctgc
    27781 tctttctatt tcagcctgct gaagaaaatg aagctggtgg tatgctcatg tatgaggacg
    27841 gtgcttttgg agattggttg ccaaaccaat tctatggtct ccatgttcgt ccagatttga
    27901 aagtcggcca gattgcgact aatactcata cactctttgc aggaacttgc gaggtgaaga
    27961 tccgtttcaa aggtaaaggt ggccacgcag cttttcctca tgaagccaat gacgccttgg
    28021 tggcggctag ttactttgtg acccaagtgc agtcagttgt tagccgcaat gtcaacccaa
    28081 tcgagggagc agtggtgacc ttcggcgttt ttcaagctgg aaccaccaac aatgtcatca
    28141 cagacacagc ttttttacat ggaactattc gtgccttgac acaggacatg agtctcttgg
    28201 tgcaaaagag ggtaaaaaca gttgcagaag gggttgcagc tgcctttgat atggaagtcg
    28261 aagtggaact caaacaaggt ggatacctac ctgttgagaa caatccagcc ttggcgcgtg
    28321 aactgatgga cttctttgac gagaaagacg gaatcgagtt gattgatatc gaacctgcta
    28381 tgacaggcga ggactttggt tatctccttt caaaggttga tggcgtgatg ttttggctag
    28441 gtatcgatag tccctacgct cttcatcacc ctcaaatgag tcctaaggaa gaagtcttag
    28501 ctattggggt ggctgcggtg tctagtttcc tgaaaaagaa ggcagcagaa tagagggctt
    28561 gtctatgaaa tcggaattac gcaagcaagt cttgcatgaa atgaaggcta tatctcaaga
    28621 gcaaaaacag gctatagacc aagctttaac cgagcgaatt ttacaacacc ccttttatca
    28681 agaagccaag gtcatcgcaa cctacctctc tttttctcat gagtttcaaa cgcgggaact
    28741 gattgagcag gcgctgaagg acggcaagaa ggttttgaca cctaagacct atcccaaggg
    28801 gcgcatggat tttgtggtct atgatccgca acagttggta aaaacttcct ttgccttact
    28861 ggagccacag ggagatttgg aagtagtgga tgcatctcag attgatttga ttcatgttcc
    28921 tggcctggct tttacgacgg atggatatcg gattggatat ggtggaggtt attatgaccg
    28981 ctatctggaa catttttctg gtcgtgcttt gagtacgata tatccttgtc aaattcagga
    29041 ctttatacct gaaaaccatg atattcctgt tcaggaggta ttaattgatg aaggaaatct
    29101 ttgatagacg ttaccctgtg acgagtttct tcctcttagt gacggccttg gtatttttac
    29161 taatgttggt cactgcaggc ggaaactttg acagggcaga tacattattt cgatttggag
    29221 ccatgtatgg gccagctatt cgcctctttc ccgagcaggt ttggcgtctc ttgtctgcca
    29281 tttttgttca tattgggtgg gaacatttca ttgttaatat gctttcactt tattatcttg
    29341 gaaggcaggt agaggagatt ttcggttcta agcagttttt ctttctctat cttttatcag
    29401 gaatgatggg caatctcttt gtttttgtat ttagtcctaa atccttagca gcaggcgcct
    29461 ctacctctct ttatgggcta tttgccgcga ttattgttct tcgctatgca actcgcaatc
    29521 cttatattca acagctaggg caatcctatc tgacactttt tgtagttaac attattggaa
    29581 gtgttctgat tccaggaatc agcctagcag gccatatcgg tggtgcagtt ggtggcgcat
    29641 ttctagcagt tatctttcca gttagaggag aaaaacggat gtataatacc agccagagat
    29701 taggagcggt agtcttgttc gtaggactcg ccattttgct tttctacaag ggaatgggaa
    29761 tgtgacgaag ttgaaagaaa atttgtgtaa tgaaaaaaga taaggcattt tttgaacctt
    29821 atctttttat tttattttat tccttctcag tcaattcttt tccaagttgg atgaggtaat
    29881 tcttcaaatc atctttgact tgtgggtgtt tgagggcgta gtcgatggat gttttcatga
    29941 agccaaactt gtctccgaca tcgtaacgag ccccattgaa ctcacgagca aatacacgtt
    30001 gtgttttatt gagggtgtcg attgcatctg tcagctgaat ttcatttcct gcacctggag
    30061 cttggttttc gaggatttgg aaaatttcag gcgtgaggag gtagcgtccg ataatagcaa
    30121 ggtcgctagg agcgtcctct ggagctggtt tttcaacaaa ggtttcaaca ctgtaaagac
    30181 catcttttcc ttcgccttgc ggagcaataa ccccgtaagc agatacttcg tcatgaggga
    30241 ctggcatgac agcgatagta gacgcgtggg tacgctcgta gtcatccatg agttgtttgg
    30301 taagtggaac agccttttcg tctgtgatat ccatcaagtc atcaccaagc ataacgacaa
    30361 aaggttcatt tccgacgaaa gccttagctt gcaaaacagc atctccgaga ccgcgtggat
    30421 gagtttggcg gataaaatgc agacgcatgt cagttgtttt atcaactagc ttcaaaagat
    30481 ctgttttccc tttttctttg aggttatatt ccaattcgaa gtttgaatca aagtggtcct
    30541 caatagaacg ttttgattta ccagtgacaa ctagaatatc ttcaatacct gatttgagag
    30601 cctcttccac gataaactgg atagttggtt tgtctacgat tggcaacatt tctttggcaa
    30661 gggccttggt tgctggtaaa aatcgagttc ctagtccagc agcagggatg actgcctttc
    30721 taacttttga tgtcataaaa atcctttcta tagagggtta agaccactca ttttctgctt
    30781 taaattcatt gttcatgatg tcataaatgg catctttgat attggttccg tgataaataa
    30841 cttggtaaat agcctgtgta atgggcatat agactccaag ttcttgggct agttcatagg
    30901 ctgctcgagt cgttgaaatt ccttcgatta ccatgcccat attagcttct atatcagcta
    30961 gggattctcc tcgtccgaga gcatctccag ctctccagtt acgagagtgg atggaagttc
    31021 ccgttacgat caaatctccc acaccagata agccgctata ggtcaatgga ctggccccga
    31081 gtgctacccc taggcgggtg atttctgcta aacctcgagc gatgatggct gccttagcat
    31141 tatcaccaaa tccaagacca tgtaaagctc cagcaccgac agcaataata tttttaagag
    31201 caccagcagt ttcaaccccg ataacatccg tattggtata aagtcggaag tagtgattac
    31261 taaatagctc ctgaacgtat tgagctgttt gtaaatcttt agaagcagca gtgattaaag
    31321 ttaggtcacg cacaatggtt tcttccgcat gactaggccc tgaaacaacg acaatatcac
    31381 tgcggagctg ttcaggaatt tcttcttcaa ggatagttga taatcgttta tggctatcag
    31441 gttctaatcc ctttgaagcg tgcatgatga tagccttatg gtccaaggtt tgtgcaactt
    31501 gttgggcaac aagtcgtgtc acttttgttg ggacaacaaa caaaatcgca tccacatctt
    31561 tcaatgtttc tgctaagtcg gtgtaggcaa tgatattttc atctagaacg acatctttaa
    31621 agtagtgctt gttagtatga taggtattaa tttcattgat ttgctcggga agatttcccc
    31681 aaatacgtac ctcgtgtcca ttgtcattta agacttgtga aagggcagtt ccccaagaac
    31741 caggccccaa gacggcgacg gtttgttttt ccatgatttc ctccttgata gagttctttc
    31801 cattattcta tcatattcta gaggattttg cacttgcatt actggggtat ggtggaaaaa
    31861 tacacaaaga ccgagatgaa gggataaact cttagtcttt agttaaagtg agaagaaatc
    31921 tgatagatag tttgattcag tatatgctat aaatagaggt aaacaactca ggaggttctt
    31981 gtaggttgcg agagtttggc gaaaaaatta aaagattacg tttggctaaa aaaatcagtc
    32041 gttcagaatt ttgtggtgat gagtctgaat taagtatccg tcaattaatt agaattgaaa
    32101 atggagaatc cagaccaaca ctaacaaagt taaaatatat cgctgaacgt ttgggggggg
    32161 tgaagattac aagttgatgc caagttatat agagttggat aaggaatacc tagaattgaa
    32221 gtatttcttg atgaggactc ctacatacga agatgaaact atcgcccaaa agaaagagag
    32281 tgtttttgct aagatttttg aagagtatta tgataggcta cctgaggaag aaagatttat
    32341 catcccaaat tattcatatc tagcactagc gaactacaca gttcaaaaat taccagaaaa
    32401 gctagttgaa atactgtcct tctggtgatt ttgcttaatt tctgatgttc gagacatgat
    32461 tgaggagatt tgtcttgatt ttttcctaaa aaagggcaga ctcctccctt ggtttgatgc
    32521 tcgattttta aaataaggtg acttattctg ttaggcatgt tttcccctgc cctctagctc
    32581 tatatggaac agggagtatc agatttatct ggcagattgt atcaaataag gcttgaaact
    32641 gttttgaata ggcgtataga cttgagaatt tgagaatatg tcgtctagca gtagagacat
    32701 attttccggc aatatgaagg aagagacgtc gaaaacgctt gatagtcaag gactttactt
    32761 catcaccagc tagctgcttt aaaaagaggt agagattata agccagacag cccatcatca
    32821 tacgtacttc attcttaatc atggtcgaac tatctgtctt atccccaaag aatcctgctt
    32881 tcctttcttt gataaagttt tcagcattcc ctcgttcacg atagaattga aacagctcct
    32941 cactatctac actgcttaaa ttgttcaaat gaactttttt acaaccataa aaaagagcac
    33001 ttaatcgtac tcttctcttt taaggattag ttgaattaat tcaaatccac tagttctcct
    33061 gtttctaggt agactaggcg ttcacaaatg ttagcaatgt aatcagcgaa gcgttccaga
    33121 tgtcctatga tataaaggta ttgagttcca ttgggaattg aggtttcttg gtctttcata
    33181 agtccaatga tttcctttga taaggcataa taatattggt caatctgttc atctttttga
    33241 gcaatactaa tagcttttga ggcttggtgc aaaggaaagg caaccaataa atcggctagc
    33301 atgctgaggg ataatttacc catttggtgt aactgttctt cgtcaggggc tagttgattt
    33361 tcttttagtt gcaaaacagc tttggcaatg cctgccatat ggtctcccat acgttcaagg
    33421 tctgaacaag aagacatgat gctaatcaca aatcgaaggt cagacacttg tggctgttgc
    33481 aaggccaaca aacgggcaca ggtcaattcg atagcgcttt gaccttggtt gatagcatga
    33541 tccttattga taattagctc tgccatctcc ttgtctttgg aggctaaggc cagtaaggct
    33601 tttgaagctg tttcaaggac aagttgccct agtcctaaaa aggattgttc taattcatgc
    33661 aattctaagt caaattgatt tctcataggt ttttccttcc ttatccgaac cgtcctgaaa
    33721 tatagtcttc tgtgcgctga tcttttggat tggtaaacac gtcaacggta tctccaaatt
    33781 cgcaaatttc tcctgttaag aaaaaagcag ttttatctga aatacgtgaa gcttgttgca
    33841 tgttatgggt aacaatgata atcgtataat ccttttttag ttgctgaatg aggtcttcaa
    33901 tttttaaagt ggagataggg tctaaggctg aagtcggctc atccattaac agaacatcag
    33961 gttctactgc taaagctcgc gcaatgcaaa ggcgttgctg ctgaccgcca gataaggaca
    34021 tggcactctt tttaagatca tctttgactt cttcccaaat ggctgcccct tttaaagatt
    34081 tctccactaa ggcatctaat tgttttttgt ctcgaatacc atgtgtcctt ggaccataag
    34141 ccacgttatc atagatagac atggcaaagg gattaggctg ttgaaaaacc atccctacac
    34201 gcttgcgtag ctgattaagg ttgaatttgc tactataaat atcttgctca tctaagagga
    34261 cttggccttc aatatggcaa gaaggaacca aatcgttcat ccggttaagg gtttttagaa
    34321 aagttgattt gccacaacca gatgggccta tcaaggcagt aatctgtctt tctggtaatt
    34381 gaatcgaaat attttttaag gcttgaaaat ccccgtaaaa taagtctagg tgtctgactg
    34441 aaaatgttcc catactagga agctcctttc acaagttttc gagataataa gcttgataga
    34501 gtatttatca ttaaaacagt aataatcaaa atcacaccgg tagcataggc ttcattgaca
    34561 tgtagcccct cacttgacag catatacata tgcagggcta gagaacgacc tgaagacatg
    34621 agactacttg gcgtattggt agaggtacct aatgtataca tgagggcagc tgtctcacca
    34681 acgatacggc caatagctag tatcactcca gctaaaatac ctggcatggc aactggtaga
    34741 acaattctaa aaacagtccg taacttacct gccccaagtc cataacttgc ttgacgcatg
    34801 ctatcactaa cagataaaag ggcttcttct gttgagcgaa taatgactgg caacaccatg
    34861 atgactgagg ttaagattcc tgataacaga gagtattgaa aacctaagaa gactacaaag
    34921 aagagcatgc caaacagacc aaaaacaatg gaaggaatcc cagacaaggt atctgaggcc
    34981 aatcgcatga ttttaacaca aagggaatct ttttttgtat attccacaag ataaaaacca
    35041 gcaaaaatcc ctatgggcaa ggctaaaaga agagcaccaa agaccagaat aacggtggaa
    35101 ataatcgctg gcataaggga aatgttctca gaagtataag tccaagaaaa gagggataga
    35161 cttagatgag gtaagccttt gatgaggata aaaccaatga ttaaaaagag agagccaaag
    35221 gttaaagctg aaaaacaata aacgagaagt tttagcaggt atttactcat aagatgattt
    35281 tcctttcaag taggcaaagt aggcattaat caagagaata aggaaaaaga gaactgctga
    35341 ggttgcaata agggcttccc tatgctgacc tgatgcgtaa gccatttcca gaacaatatt
    35401 ggttgttaag gttctggttc ctgaaaagag tccacttgga ataatcggct ggttgcctgc
    35461 caccaaaata actgccatgg tttcacctac tgcgcgaccg attcctaaaa taactgctga
    35521 taaaatacca gatctcgcag ctggcaagat gacactaaaa atactccgtt catgactagc
    35581 tcctagagcc aagctaccag aataatacgt tttgggaact gttcggatag cagattctga
    35641 caaactgata atggttggca aaatcattat tcctaatagt aacgaagcgg ttaggacact
    35701 catgccattt cctaaaaagg ttctaatcca aggcaccaat aattgtaggc cgaaaaaacc
    35761 ataaacaata gatggaatgg ccgccatcaa gttgatagct gattttaaga agccatagac
    35821 gggctttgga caataataaa ccataaacac cgatgtcaag atgcctgttg gcaccccaat
    35881 cacaatcgct cctaaggtaa ttaataagga accaacgatc attggtaaaa taccatagct
    35941 tgccggaatg ttcgttggcg accaatcact gcctaataaa aaacgggcaa agccgtagtt
    36001 agccatgaaa ggtaagccat tactaaaaat aaagaaacag attagcaaaa tagctacaac
    36061 agctactgtt gcactcatga aaaaaattgc cctaaaaact gcttctttga aggcttgttt
    36121 tgtcacatct tgtcctttct agtgaagaaa gtaagggaga tacgacacct ccctacttgc
    36181 cttctttatc ttattgtacg atgaaacgtc tgcatctctt tagagattta tggagcaaac
    36241 attttattta atcttgtccc aggtggttaa tttgccacta aaaacgtctg caagttcagc
    36301 catactgact tggcttgcct tattgtcatt attgaccaca acagcaatac cgtctaaagc
    36361 aatagcatca tgggtgagac tcttaccttc ttcaggagtt aattccctag aaaccatacc
    36421 aatatcagcg gttttctcct taacagcggt aatacctgct gaagacccat tagaggtaat
    36481 atcaatcgta acttctggat tttctttttt ataagcttct gctaattttt ccattaaaga
    36541 agatactgaa gtggaaccta caacagacaa cttgcctgat aagtgttggc ttgtatattc
    36601 tgtggtttcg gttttagctt caataaattt attatctgtg accacttgtt gaccttgttt
    36661 ggagtggata aagctgataa aatcttgacc tagcttggaa agattagaag accaaacaat
    36721 gttgaaggga cgttgaagag ggtattcacc atctaaaact gtgtctcgac tagccttgac
    36781 accatcaatc tctaaagcct tgacagattt cgttaaagat cccaaggaga tgtagccgat
    36841 agcattagca ttcccttgaa ctgctgagag aacaccttct gtactatttt gaatcacagc
    36901 tgttttggca gtgttgtcaa tttttttatc accgtctttt ttgagaatcc ctgtgatttc
    36961 tgtgaaggca ccccgtgttc cagagccatt ttctcgtgaa atcacctcaa tcgttcctga
    37021 agctgactgt ttggaagcag ctgactgatt gccacaggca acaagcccaa atcctgataa
    37081 gccaatggct gcaagagtaa gcattttttt gaatttcata ataatcacct ttatctctat
    37141 gtatttttct tgtgtaggct tactacattt atagtctaac aagtctttgt aaaggtttat
    37201 ccctgattca tgtaaagatt gtgtaaagaa tcaaaaaaag ccacttttga aaaatggctg
    37261 ctcctaaaaa tagctttaaa aattattagt cctgtgcgaa agattggtta ggaagaaaaa
    37321 tcgtgaagca actgcctctg ccaagctgac tcgtcaccgt gacttggcca cctaataatt
    37381 gactgagttc tttgacaatg gcaaggccaa gaccagtgcc accagtttgt ctgcttcgac
    37441 ctttattaac tcggtaaaaa cgttcaaaaa tacgatcctg ctctaattga ctaataccaa
    37501 tccctgtatc tgatacagaa atcttaatgc cttcgttcac cttttgggtc ttgacctcaa
    37561 tttttccccc ttgttcagtg taacggatgg cattggataa aagattgagt aagatttggg
    37621 aaagtaattg actatctgat acgagggtga catcatctgg cacctgcacc tttagctgta
    37681 aatccttctt cttgagctga ggttgcaagc tttgagtcaa atcctgtaca aattctgcca
    37741 aagaaagggt cgtccattgt ataggcattt gttgagcctt agataaggta agaagatgct
    37801 caacaatatg ctcaagacgc aagctttctt tgtaaataat gtctagaaag tcatccttga
    37861 gcgcttcttc ttcagctgac atccccttaa tggtttcagc aaagccctta atcgaagtaa
    37921 ctggtgtcct caattcatgg gaggcatttg agacaaaggc taaatttaac ttttcataag
    37981 ttctaatcgt tgttaaatca tatagcaaga cgagcacagc ttccacagat tgggtggggc
    38041 taaaaacggg aactgctgtc acttctaaaa tcaagtcacc ctcatgaaac ccacttactt
    38101 cttgttttaa ccttgttttt tgatcaaagg cttggtgaac taaatttcga atatccatcc
    38161 gtttgaggtc atcaagtgaa cttatgtcgc cgtccacatc gggaaaataa tgaggcagag
    38221 agcgactgga taataacatc tgaccttgag cggaaactaa aaacgtcccc atggttaggt
    38281 gcgacagaag aacctccatt gtttcggcta ggtccttgta ttgctgatcc tgttgggaga
    38341 ctttggtttt tagggcagac acatactgag ccaaagactt taagtcttct tgcccttttt
    38401 ctaaaaagta ttcactactg gtcaagagag gttggtgcaa ggtctcaaaa gcaacttccc
    38461 atttccaaag gcaaaagagc cagtagccac cttgtcccaa agaaagggct agaagaaaga
    38521 gaccgatgcc tttactgatc caagttaatg ccatccctgc aatcagaatg aggctaacac
    38581 ttagattgac tagccaaaat tgaaggtagc gtttcatcta taactccttg aacttataac
    38641 cataaccccg aatggttcga ataaattgag gggctttagg attgtcttca attttttccc
    38701 tcaacttacc aatatgaacg tccaccaaac gtgtttcctg cccaaagtca tacccccaga
    38761 tacgttccaa aagacgctct ctagtcagtg tcatgttggg atgtttcata agatagagca
    38821 agagttcaaa ttcttttggg gtcaaactca gtaacttatt cgccttgtag acttcatgac
    38881 gctcagggta tactttcaag gtcccaaata gccaagaatc gtcagcgata ttatctgaat
    38941 catctccttc ttgttctcct ttagttcgcc tgaggacagc cttgacacgc gccagcaatt
    39001 ctctagggct aaaaggcttg gtcaggtagt catcagcccc taattccaag gccaaaacct
    39061 tatcaaattc atcacttttc gcagaaacca tcataattgg agttttgacg cctttggctc
    39121 tcagccgctt acaaacttcc atgccatcta attgtggtaa catgatatca agcaagataa
    39181 aatcaaaggg ttctgtttct gccaaagcta aggccttccg tccatttgtt accaattgag
    39241 tagaaaagcc ttccttactt aaatggtagt caagcaattt cagaatgtgt tcttcatcat
    39301 ccactaataa gacttgtttt gtcatctatt atctcctatt ggtaacatta taacacaatt
    39361 gtcagaaatc ctaacattgc taaatcagat taaatttgct tatcaagact agtatctggt
    39421 caaacgctca atcatctcct tgtgctctgg ataggtcgcc agtagatcta ccctttcaaa
    39481 taattcaaaa tcctcaaatt caaaaccagg agcaacaaga caagaaacca gagcataatc
    39541 cttatcaact gttgatcccc aaatagtgcc cttaggaaca cagtagtgaa gttgttgccc
    39601 tttggatatg tccaggccta aagtgactgc ttcgtagtga ccatctgctg taatcatgtg
    39661 aacagtaagt ggggatcctg catgaaaata ccagatttca tctgctgtca atcggtgaaa
    39721 atgtgaagga ttcgtttctt ctaataagaa ataaatactg gtataaagcg cccttccctt
    39781 accagcaagg tttatagtgt ctgaagcttt ttttgtttgt ctaaaatagc caccttcaac
    39841 atggggagct aactctagag ttcttatcaa gtcttcttta tccgtcggag ccaatgggtt
    39901 gaagtaactc ttgttcaaag gtggtgttac gatttcaaga actcctctca gctctgagga
    39961 cacgataatg attgatgcga cggaagtaca aatcaatcgc cctaaaaaaa gaattagcga
    40021 attattctgg taaaaaaatg ccacgctatg aaggctcaag cgattgtcac aagtcaaggg
    40081 agaattgttt c
//
LOCUS       DAVBIC010000014        39717 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.014, whole genome shotgun sequence.
ACCESSION   DAVBIC010000014 DAVBIC010000000
VERSION     DAVBIC010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 39717)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39717)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39717
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.014"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            <1..178
                     /locus_tag="VQ664_000696"
     CDS             <1..178
                     /locus_tag="VQ664_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="choline-binding protein D"
                     /protein_id="HET2788900.1"
                     /translation="TGWVKDGDTWYYLEASGAMKASQWFKVSDKWYYVNGLGALAVNT
                     TVDGYKVNANGEWV"
     gene            579..1700
                     /gene="mnmA"
                     /locus_tag="VQ664_000697"
     CDS             579..1700
                     /gene="mnmA"
                     /locus_tag="VQ664_000697"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HET2788901.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMTLGADYVATGHYARVARDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLEKPEVRRLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFTREMPEEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            1841..2296
                     /locus_tag="VQ664_000698"
     CDS             1841..2296
                     /locus_tag="VQ664_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET2788902.1"
                     /translation="MTQQDFRTKVDNTVFGVRATALIVQNHKLLVTKDKGKYYTIGGA
                     IQVNESTEDAVVREVKEELDVKAQAGQLAFVVENRFEVDGVSYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKLQNIQLVPAFLKTALPDWEGQLRHIHLEE"
     gene            2306..4219
                     /gene="mnmG"
                     /locus_tag="VQ664_000699"
     CDS             2306..4219
                     /gene="mnmG"
                     /locus_tag="VQ664_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HET2788903.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDEILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEVPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWARFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEDLDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
     gene            4408..4497
                     /locus_tag="VQ664_000700"
                     /pseudo
     CDS             4408..4497
                     /locus_tag="VQ664_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(4643..6322)
                     /locus_tag="VQ664_000701"
     CDS             complement(4643..6322)
                     /locus_tag="VQ664_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HET2788904.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     VCTGDFKFDFTPVGEPADLHRMAALGEEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEVLILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLRLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(6324..6557)
                     /locus_tag="VQ664_000702"
     CDS             complement(6324..6557)
                     /locus_tag="VQ664_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HET2788905.1"
                     /translation="MIYKVFYQETKERSPRRETTRALYLDIDASSELEGRITARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFEITEF"
     gene            6939..7160
                     /locus_tag="VQ664_000703"
     CDS             6939..7160
                     /locus_tag="VQ664_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000184674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2788906.1"
                     /translation="MTNQVLEENYLCDSLLAFSPPRDLCRLVCILLWIKCLDALLMLG
                     FFVWGCRDSRFTTRKFHPIYQDEVVFAFF"
     gene            complement(7373..7525)
                     /gene="cibB"
                     /locus_tag="VQ664_000704"
     CDS             complement(7373..7525)
                     /gene="cibB"
                     /locus_tag="VQ664_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HET2788907.1"
                     /translation="MMKDLNNCREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            complement(7527..7712)
                     /gene="cibA"
                     /locus_tag="VQ664_000705"
     CDS             complement(7527..7712)
                     /gene="cibA"
                     /locus_tag="VQ664_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HET2788908.1"
                     /translation="MTNFDILDNQFLSLSENELSDIDGGLAPLVIFGVAVSWKAIAGG
                     TALIGSGLAAGYFLGGD"
     gene            7890..8573
                     /gene="tsaB"
                     /locus_tag="VQ664_000706"
     CDS             7890..8573
                     /gene="tsaB"
                     /locus_tag="VQ664_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HET2788909.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQVLAETTINIKKNHSITLMPAID
                     FLMESLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLTHTLNIELVGMSSLLALVPY
                     QQEGLFVPLMDARRNNVYAGFYENAKPVMPEAHLSFEEVLEKVKGASQVTFVGEVGPF
                     VEQIQEHLPRTNYKETLPNAANLALLAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            8570..9007
                     /gene="rimI"
                     /locus_tag="VQ664_000707"
     CDS             8570..9007
                     /gene="rimI"
                     /locus_tag="VQ664_000707"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HET2788910.1"
                     /translation="MIEIKRIQQQPDLAQAIYAVMAAVYLVSPWTLEQIQADLSQDQT
                     WYALAYDGAEVIGFLAVQENLFEAEVLQIAVKGAYQGQGIASALFAQLPTDKEIFLEV
                     RKSNQRAQAFYKKEKMAVIAERKAYYHDPVEDAIIMKREIDEG"
     gene            8997..10007
                     /gene="tsaD"
                     /locus_tag="VQ664_000708"
     CDS             8997..10007
                     /gene="tsaD"
                     /locus_tag="VQ664_000708"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HET2788911.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLYHNAEQKGESLSTEDLCASFQAAVMDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWDLNAKPSLAFDT
                     ME"
     gene            complement(10053..11353)
                     /locus_tag="VQ664_000709"
                     /pseudo
     CDS             complement(10053..11353)
                     /locus_tag="VQ664_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(11629..11980)
                     /locus_tag="VQ664_000710"
                     /pseudo
     CDS             complement(11629..11980)
                     /locus_tag="VQ664_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(12087..12379)
                     /locus_tag="VQ664_000711"
                     /pseudo
     CDS             complement(12087..12379)
                     /locus_tag="VQ664_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            12622..13828
                     /locus_tag="VQ664_000712"
                     /pseudo
     CDS             12622..13828
                     /locus_tag="VQ664_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
     gene            13821..14469
                     /locus_tag="VQ664_000713"
                     /pseudo
     CDS             13821..14469
                     /locus_tag="VQ664_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397244.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
     gene            14479..16095
                     /locus_tag="VQ664_000714"
     CDS             14479..16095
                     /locus_tag="VQ664_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2788912.1"
                     /translation="MYTIIKSNIKKFSLLTIFIVAGQLLLIYAATINALVLNELIAMN
                     LERFLKLSIYQMIVWCGIIFLDWVVKNYQVEVIQEFNLEIRNRVATDISNSTYQEFHS
                     KSSGTYLSWLNNDVQTLNDQAFKQLFLVIKGISGTIFAVVTLNHYHWSLTVATLFSLM
                     IMLLVPKIFASKMREVSLNLTNQNEAFLKSSETILNGFDVLASLNLLYVLPKKIKEAG
                     ILLKMVIQRKTTVETLAGAISFFLNIFFQISLVFLTGYLAIKGIVKIGTIEAIGALTG
                     VIFTALGELGGQLSSIIGTKPIFLKLYSINPIESNKMNDIEPNEVNRDFPLYEAKNIC
                     YKYGDKEILKNLNFCFQRNEKYLILGESGSGKSTLLKLLSGFLRDYSGELRFCGDDIK
                     KTSYLNMVSNVLYVDQKAYLFEGTIRDNILLEENYTDEEILQSLEQVGLSVKDFPNNI
                     LDYYVGDDGRLLSGGQKQKITLARGLIRNKKIVLIDEGTSAIDRRTSLAIERKILDRE
                     DLTVIIVTHAPHPELKQYFTKIYQFPKDFI"
     gene            16115..16959
                     /locus_tag="VQ664_000715"
                     /pseudo
     CDS             16115..16959
                     /locus_tag="VQ664_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813546.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            17027..18528
                     /locus_tag="VQ664_000716"
                     /pseudo
     CDS             17027..18528
                     /locus_tag="VQ664_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819023.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase"
     gene            18540..19289
                     /locus_tag="VQ664_000717"
     CDS             18540..19289
                     /locus_tag="VQ664_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HET2788913.1"
                     /translation="MSDNTKYIFLSPHLDDAIFSCGDYISKLTSEGEIVLVITIFSGY
                     PLSQQLQPSAKQFHKLCNLGKYPIEERKKEDRLACERLQCDFRHLSYYECLYRKDRNG
                     NFLYRHIYSKLKNEDTLKNDIIKELLMHLDDKCVVYCPLSLGDHVDHVFVNSIGRALE
                     FMRYKVIYYEDFPYVSDSSMVSYMGKTKELKMYQEELDEKHYIDRISSILCYKSQILI
                     IWKSVEKLLNNIKELYLRNGAAYSIRFWIKK"
     gene            19302..20474
                     /locus_tag="VQ664_000718"
     CDS             19302..20474
                     /locus_tag="VQ664_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HET2788914.1"
                     /translation="MNIAVIGLGHVGLAYALLFASKYKVVAYDIDSVKINNLKKGTLP
                     SKNEELMKFFCENNLNITFFDTFSEIKNNIDYYIIALPTDYDEKIGSFNTYEIEQTVS
                     KILRVKPNGKIILKSTVPIGFSNKLKRLFDTKNIIFVPEFLREGCSIYDNLYPSRIVV
                     GDETVEGRKIAELFLSISTHSTANIKNVMLVSPTEAEAIKLFSNTFLALRVAFFNELD
                     SFAERRSLNAEVVIKGVCLDPRIGNFYNNPSFGFGGYCLPKDTRQLKKEFIEINAPVI
                     EAIDISNTNRKQFIVKQILERKPKIVGIYKLGMKYNSDNYKESAILSIINELLIVGIK
                     ILVYEPNLNVSIDNVIFEKNFELFIKQSDLIVANRWDRGLEAYKDKVYTRGIWIRD"
     gene            20869..21732
                     /locus_tag="VQ664_000719"
     CDS             20869..21732
                     /locus_tag="VQ664_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HET2788915.1"
                     /translation="MIEKMELGEFYKELRLARKLKQSDVACAGLTASQLSKFELGQSM
                     LSADKLILAIQGINMNFDEFGHKLNNYQESPHMRIGRRVVDCFSHQDIAALEQLLEEV
                     DQEQMAQTYRRLNAIVIKNALHSLDKSYPLTEEDSEFLTTYLYAIESWTWFELYLFCN
                     TMPFLSNQDLIFLSTSLLEKSKEFKELVHNRWYMKSGYLNIISELMERKLFSYIPIFE
                     AELERMLRPYDVFEKVLWQFLKKMQIFLQTKGSNQKEIEHFIQSLQVLENPQLTALFE
                     LRLQQYKELID"
     gene            22018..22251
                     /locus_tag="VQ664_000720"
     CDS             22018..22251
                     /locus_tag="VQ664_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2788916.1"
                     /translation="MLNLQFAETMELTEAELQDVRGGNLVNSMGGGGRSGISGWGVPG
                     IYPGWGNQGMSPNRGAFDWTIDLADGLFGRRRR"
     gene            22273..22950
                     /locus_tag="VQ664_000721"
     CDS             22273..22950
                     /locus_tag="VQ664_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2788917.1"
                     /translation="MKKMKEVKFHLATGLLILTYYLIFNVTSDLDFMVALSDNMYYVF
                     QVLLVLILGTIATIAFVKSEHWKECGRFQFRWSYLGVFLLSFFLLFVWANLTTYIFPR
                     TQNGSTVVEVATSLTGISYFVTRILYTSIIAPVSEEVVCRGLLMTSLSKVKRYYLDVL
                     VSAAIFGAMHVLQYGWITTDFIKYFGMGLIFCMMFRYTRSIYWAIALHASWNSFLLIV
                     TLLVFGY"
     gene            22962..23627
                     /locus_tag="VQ664_000722"
     CDS             22962..23627
                     /locus_tag="VQ664_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2788918.1"
                     /translation="MKKIISHRYFIIVFLLVIADQKFSVLVLRSDLVAGLSDFAYYLS
                     DMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVAWNFVTFFLFPP
                     TRNEISYQHAAPTFTGATAFLMYFFYPVIAGPIFEDMIYRGLVMTALEKGKKWGLDVL
                     GSAILFGVSHISNHGWVLTDFFVYMGGGLIFAVLFRMTKSIYWPIGLHIVYNGIGQLL
                     MLL"
     gene            23699..24925
                     /locus_tag="VQ664_000723"
     CDS             23699..24925
                     /locus_tag="VQ664_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET2788919.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISETLPQVLQIFLGVLADFQHHRVLKYTVISFTKFLLYSIVSLSLSGQSFSLL
                     LVTFICLLNLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTISYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPISTLFLRNQPFLNLQTGQSLALLATLEL
                     SALILGSLMSGYLQHTISIKIALYASLLLQLLLLVGFATAHFGLILIFSFLDAFFAGI
                     LSPRLQELVFKQIPEESMGAVQSSIGAITVVLPSLFTIALGTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
     gene            complement(25276..25353)
                     /locus_tag="VQ664_000724"
                     /pseudo
     CDS             complement(25276..25353)
                     /locus_tag="VQ664_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            25424..26080
                     /locus_tag="VQ664_000725"
     CDS             25424..26080
                     /locus_tag="VQ664_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HET2788920.1"
                     /translation="MPTALGYVSIGLACGTIGAPYVTPVEMGLMSLFVYAGSAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSLWYNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTALGGLLPNPEIFGLDFALVGMFIGI
                     FASQFQIMQRRIPVRNLLIILAVVAVSFFLLLTVVSQSLAVLFATLLGCSMGVVLDGQ
                     "
     gene            26070..26393
                     /locus_tag="VQ664_000726"
     CDS             26070..26393
                     /locus_tag="VQ664_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HET2788921.1"
                     /translation="MVSKYLLLAVIFSDLVTWILRMIPFILVKYKGLPAIVERFLKFL
                     PVSIIFALILSSVVTGKVGSLPQIKWLDFLAVFPTAWVAFRYRNLVGTVLFGVVLIAV
                     LRLVF"
     gene            26497..27327
                     /locus_tag="VQ664_000727"
     CDS             26497..27327
                     /locus_tag="VQ664_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2788922.1"
                     /translation="MKKIVKYSSLAALGLVAAGVLAACSGGAKKEGQAASKKEIIVAT
                     NSSPKPFNYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYQMAV
                     NNISYTKERAEKYLYAAPTVKDPNVLVVKKDDSSIKSLDDVGGKSTEVVQGTTSAKQL
                     EDYNKQHSDNPTILNYTKANLQQIMGHLSDGQFDYKISDKITVETVIKNQGLDNLKVI
                     DLPSDQQPYVYPLLAKGQDELKTFVDKRIQELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            27368..27445
                     /locus_tag="VQ664_000728"
                     /pseudo
     CDS             27368..27445
                     /locus_tag="VQ664_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253911.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC protein"
     gene            27549..28379
                     /locus_tag="VQ664_000729"
     CDS             27549..28379
                     /locus_tag="VQ664_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2788923.1"
                     /translation="MKKIVKYSSLAALALVAAGVLAACSGGAKKEGQAASKKEIIVAT
                     NGSPKPFIYEENGELTGYEIEVVRAIFKDSDKYNVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            28533..29387
                     /locus_tag="VQ664_000730"
     CDS             28533..29387
                     /locus_tag="VQ664_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HET2788924.1"
                     /translation="MKIKKWLGLAALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIADTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEESS
                     DGLDQPVW"
     gene            29487..30860
                     /locus_tag="VQ664_000731"
     CDS             29487..30860
                     /locus_tag="VQ664_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HET2788925.1"
                     /translation="MVFPSEQEQIEKFEKDHVVQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLRGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEERMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYYTHIELVE
                     ELIRSYE"
     gene            30853..31914
                     /locus_tag="VQ664_000732"
     CDS             30853..31914
                     /locus_tag="VQ664_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HET2788926.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSGLSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSNPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGASTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGGQ"
     gene            31916..32608
                     /locus_tag="VQ664_000733"
     CDS             31916..32608
                     /locus_tag="VQ664_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2788927.1"
                     /translation="MESLIQTYLPNVYKMGWAGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAVPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIIIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(32638..33207)
                     /locus_tag="VQ664_000734"
     CDS             complement(32638..33207)
                     /locus_tag="VQ664_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HET2788928.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIALFFLGTKHGAGSFLPGIICGLLADGVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVAPNPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            33342..33956
                     /locus_tag="VQ664_000735"
     CDS             33342..33956
                     /locus_tag="VQ664_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HET2788929.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLAGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKVLLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            33958..35604
                     /locus_tag="VQ664_000736"
     CDS             33958..35604
                     /locus_tag="VQ664_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET2788930.1"
                     /translation="MKQFWLHTLLRTYSSVMIIIIASFAILLSYADWDSREKEAQRVA
                     QRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQLERKASPY
                     ISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDFKPAGNSFA
                     IPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGHTPMAVTVTSPFDTEIFHIGETVDR
                     ESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLTLRQTFANY
                     QKQVVDLVESIQVIAQGEEGRRIDISEKDQELLLIAETTNDMLDRLEKNIHDIYQLEL
                     SQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLRNNISDERE
                     TLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVENYFAHGVD
                     HRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQKYFEHRASYSDQRQ
                     SIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            35616..36902
                     /locus_tag="VQ664_000737"
     CDS             35616..36902
                     /locus_tag="VQ664_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2788931.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFTIPYYVLGQDWQIFISDQPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRVPITKQLFIQFVMDVF
                     HLFEHLKADDLTDIVKTIHAIQSFDELVPYIKETLSSFFGQYRMNENVVSVLEVIGCD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            36963..37496
                     /locus_tag="VQ664_000738"
     CDS             36963..37496
                     /locus_tag="VQ664_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2788932.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRTAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKASAEEEETEELA"
     gene            37574..38044
                     /gene="nrdI"
                     /locus_tag="VQ664_000739"
     CDS             37574..38044
                     /gene="nrdI"
                     /locus_tag="VQ664_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HET2788933.1"
                     /translation="MKIISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(38337..39599)
                     /locus_tag="VQ664_000740"
     CDS             complement(38337..39599)
                     /locus_tag="VQ664_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HET2788934.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIVIIKFFSGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
BASE COUNT        12063 a         6877 c         8571 g        12206 t
ORIGIN      
        1 aacaggttgg gtgaaagatg gagatacctg gtactatctt gaagcatcag gtgctatgaa
       61 agcaagccaa tggttcaaag tatcagataa atggtactat gtcaatggtt taggtgccct
      121 tgcagtcaac acaactgtag atggctataa agtcaatgcc aatggtgaat gggtttaagc
      181 cgattaaatt aaatcatgtt aagaacattt gacattttaa ttttgaaaca aagataaggt
      241 tcgattgaat agatttatgt tcgtattctt taggtaccta tcttatgatt tcaggaaatg
      301 tcattaaaaa aacgactcct tttctctaac ttgaaaaata gattagagaa aatgggttgt
      361 tttatttatt atagttattt gaatgaagat aagaagaagg tatactcaca tcattcacat
      421 aatctgtatg ttgactataa gtttaaaaaa acaattttta agctcttcct tgtcttctcc
      481 aaccaagcgt gttataatga atactgctca agcgaccttc aatcgtgaag cacacacgac
      541 cttcaatcgt gaataaacga atagatggga gacttaccat gagtgataac tctaaaacac
      601 gtgttgtcgt ggggatgagt ggtggtgttg attcgtcggt gacggctctt ttgctcaagg
      661 agcagggcta cgatgtgatc ggtatcttca tgaagaactg ggatgacaca gatgaaaacg
      721 gcgtctgtac ggcgaccgaa gattacaagg atgtggttgc ggtggcagac cagattggca
      781 ttccctacta ctctgtcaat tttgaaaaag agtactggga ccgcgttttt gagtatttcc
      841 tagcggaata ccgtgcaggg cgcacgccaa atccggacgt tatgtgcaac aaggaaatca
      901 agttcaaggc ctttttggac tatgccatga ccttgggggc agactatgta gcgactgggc
      961 attatgctcg agtggcgcgt gatgaggacg gcactgttca catgcttcgt ggcgtggaca
     1021 atggcaagga ccagacctat ttcctcagcc aactttcgca agaacaactc caaaaaacca
     1081 tgttccctct gggacatttg gaaaagcctg aagtacgcag actagcagaa gaagcaggcc
     1141 tttcgactgc taagaagaaa gactcgacag ggatttgctt tatcggagaa aagaacttta
     1201 aaaactttct cagcaactac ctgccagctc agcctggtcg catgatgact gtggatggtc
     1261 gcgatatggg cgagcatgca ggtcttatgt actatacaat cggtcagcgt ggcggactcg
     1321 gtatcggtgg gcaacacggc ggtgacaatg ccccttggtt cgttgtcgga aaagatctaa
     1381 gcaagaatat tctctatgta ggacaaggat tctaccatga ttcgctcatg tcaactagcc
     1441 tagaagccag tcaagtccac tttactcgtg aaatgccaga agagtttacg ctagaatgta
     1501 cggctaaatt ccgttaccgt cagcctgact ctaaggtgac cgtccatgtc aaaggagaca
     1561 aggcagaagt tatctttgcg gaaccacaac gcgcgattac accaggacag gcagttgtct
     1621 tttacgatgg cgaagagtgt ctaggtggcg gtttgattga caatgcttac cgcgatggac
     1681 aagtttgtca gtacatttag attgacaaat tttctcaatt tgctacaata ataacagcaa
     1741 tagaaatgat ggtcaaagct catggatgtt gcaggctttt ttgtcctgca cttctttgta
     1801 gttttgactg tttttgtgtc gtttaaggga aaggacaaga atgactcaac aagactttcg
     1861 gacaaaagta gacaatacgg tttttggtgt tcgggctaca gccttgattg tccaaaatca
     1921 caagcttcta gttaccaaag acaagggcaa gtattacact attggaggtg cgattcaagt
     1981 caatgaaagc acggaagacg cggtagtccg tgaagtgaag gaagaactgg atgtcaaagc
     2041 tcaagctggg cagctagctt ttgtggttga aaatcgtttt gaagtggacg gcgtttccta
     2101 tcacaatatc gagtttcatt atctggtgga tttgcttgaa gatgccccgt tgaccatgca
     2161 ggaagatgag aaaaggcagc cctgtgagtg gattgacttg gataagctcc agaatatcca
     2221 gctagttcca gcctttttaa aaacagccct accagattgg gaaggccaac taagacacat
     2281 tcatcttgag gaataggaga gaaacatgac ttatcatttt actgaagaat acgatattat
     2341 tgtaattggt gcgggacacg ctggggttga ggcttccttg gccgctagcc gtatgggctg
     2401 taaggtcctg cttgcgacca tcaatattga aatgctggct ttcatgcctt gtaatccctc
     2461 tatcggtggt tctgctaagg ggattgtcgt acgtgaagtc gatgccctcg gtggcgagat
     2521 ggccaagacc attgacaaga cttacatcca gatgaagatg ctcaacacag ggaagggacc
     2581 agccgttcgt gcccttcgtg cgcaggctga taaggaactt tactctaagg aaatgcgcaa
     2641 gacagttgaa aatcaagaaa atctgaccct tcgtcaaacc atgattgatg agattttggt
     2701 ggaagatggc aaggttgtcg gtgtgcgtac agccacccat caagaatatg ctgctaaggc
     2761 tgttattgtg acgacaggga ctgctctccg tggggaaatt atcatcggag acctcaagta
     2821 ctcatcaggt cctaaccaca gcttggcttc tattaaccta gctgacaatc tcaaggaact
     2881 gggtctcgaa atcggtcgtt tcaagacagg aacccctcca cgtgtcaagg cttcttctat
     2941 caattacgat gtgacggaaa ttcagccagg agacgaagtg cctaatcatt tctcatacac
     3001 ttcacgtgat gaggattatg tcaaagatca agtgccatgc tggttgacct ataccaatgg
     3061 taccagtcat gagattatcc aaaacaacct ccaccgtgcg cctatgttta caggtgtggt
     3121 caagggagtg gggcctcgtt actgtccgtc gattgaagac aagattgtgc gctttgcgga
     3181 caaggaacgt caccaactct tccttgagcc agaagggcgc aatactgagg aagtctatgt
     3241 tcaaggactt tcaaccagtc tgcctgagga tgtccagcgt gacttggttc attccatcaa
     3301 aggtttggaa aatgcagaga tgatgcggac aggttatgct attgagtatg atatggtctt
     3361 gcctcatcag ttgcgtgcga ctttggaaac caagaaaatc tcaggtctct tcactgctgg
     3421 tcagacaaat ggaacatcag gttatgaaga agctgctggc caagggatta tcgcgggtat
     3481 caatgcggct ctgaaaatcc aaggtaaacc tgagttgatt ctaaaacgaa gtgacggtta
     3541 tatcggggtg atgatcgacg acttggtgac caagggaacc attgaacctt accgtctctt
     3601 gaccagtcgt gctgaatacc gtctcattct tcgtcatgac aatgctgata tgcgcttgac
     3661 tgagatggga cgcgagattg gccttgtgga tgatgaacgc tgggctcgtt ttgaaatcaa
     3721 gaaaaatcaa tttgataatg agatgaaacg cctagacagt atcaaactca agccagtcaa
     3781 ggaaaccaat gctaaggttg aggaaatggg cttcaagccg ttgacagatg cggtgacagc
     3841 caaggaattc cttcgccgtc cagaagtttc ttaccaagat gtggtggcct tcatcggacc
     3901 agctgcagaa gacttggatg acaagattat cgaattgatt gaaacagaaa tcaagtacga
     3961 aggctatatt tccaaagcca tggatcaggt tgctaagatg aaacgtatgg aagaaaaacg
     4021 cattccagcc aatatcgact gggatgacat cgattctatt gcgacggaag ctcgtcagaa
     4081 gttcaaactc atcaatccag aaaccatcgg ccaagccagc cgtatttcgg gagtaaaccc
     4141 agcagatatt tctattttga tggtgtatct ggaaggtaaa aatcgtagta tttctaaaac
     4201 tcttcaaaaa tcaaaatgat acgtcgtcgg cttcttacga atgagttcaa agcttggctt
     4261 tgattcatct ccaacctccc atagttcccc gaactatggg agctaactca agttatgcat
     4321 tttcctagcc ttctggtctg attttcattg agttttaatc tcaaaagaaa gcatagagaa
     4381 aaacagctcc gaagacgggg ctgttttgtt gacttgtact caatgaaaat caaagagcaa
     4441 actaggaagc tagccgtagg ttgctcaaag cactgctttg aggttgtaga tagaactgac
     4501 gaagtcagct caaaacacag ttttgaggtt gtagatagaa ctgacgaagt cagctcaaaa
     4561 cacagttttg aggttgtgga tagaactgac gaagtcagta acatatatac ggcaaggcga
     4621 agctgacgtg gtttgaagag tattattctt catctggtgt gaggatcatc gggatgatga
     4681 tcggttcacg ttcggtattt tcatagagga aggggcgaat agcgttgaca atggcaccat
     4741 tgacagattg cacgctagca tccttatttt tcagtgcgat acgaatggca ttgaagagga
     4801 tacgctggct ttggcgaatc aagtctccag actctctcat gtagacaaag cctcggctga
     4861 ggatatctgg gccagacaga atcatctgcg atttgaagtc aacagttgcg actgccagaa
     4921 cgacaccgtc ttcagataga tcgcgacgat ctttgaggac agctgcgcca atttcaccga
     4981 tacgatttcc atcgacatag atatcttggg cgttgaaatg acctgcgata cgagctgagt
     5041 cagcagtaag ggcaagcaca tcgccattgc tcatgataaa gatattgtct ttctcaacac
     5101 cagtatccac tgctagtcca gcgtggactt tttgcatgcg gtattcaccg tggacaggca
     5161 tgaagtattt tggcttaatc aagcggagca tgagtttttg ctcttgctga ccaccgtgtc
     5221 cagatgtatg gatattgttc actttaccgt ggataacttc gacaccagct tcagaaatga
     5281 tgttaatcag cttgttgacg ctagtagtgt ttccagggat gggactagaa gagaagataa
     5341 cggtatcacc tggttgtaat tgtacttgac ggtgggttcc gttggcgata cgagagaggg
     5401 ctgccatagg ctcaccctga ctacctgtac agaggataag aacttctcct gcaggataat
     5461 ctttgatttc atttggctcg ataaaggttc ccttaggagc tttgatgtag ccaagatcga
     5521 ttccgttgac aatggccttt tccatagaac gaccaaagac cgcaatcttg cgtccagtct
     5581 taacagcagc ttctgttgcc tgctggagac ggaagatatt tgaggcaaag gatgcaaaga
     5641 tgatacgtcc ttcaatacct tggataatct tcataatgga ctgaccaacg actttttcag
     5701 agttggtaaa ggttggtact tccgcatttg tcgagtcaga caggagacag agcacgcctt
     5761 cttcaccaag cgcagccata cgatgcaagt ccgcaggttc tccaactgga gtaaagtcga
     5821 acttaaagtc acccgtacag acgattttcc cttgaggagt atgaatgaca atccccaaag
     5881 gctctggaat agagtgagtc gttctaaaga aagttgcctt gagattttta aaggtcaact
     5941 cggtgttgtg gttgatttcg taaagtttgg cgttgcgcaa gaggccgtgt tcttcgagtt
     6001 tcccacggat caaagccaag gcaagcggtc cagcgtagat agggacattt gcttgcttga
     6061 gtaggaacgg aatcccacca atgtggtcct cgtgtccgtg tgtgattaaa acagccttga
     6121 cgcggtcgat attgtctacg atgtaagagt agtcaggaat gacatagtcg ataccaagca
     6181 agtcatcttc tgggaattta atcccagcat cgacgatgat aatctcgtct tggtattcaa
     6241 ttccgtaagt gtttttcccg atttctccta gaccaccgat ggcaaaaaca ccgacttctt
     6301 caggtttaag agtgtaggcc atattagaac tccgtaattt cgaaggcgcc agtttctttt
     6361 tcgtaatcga gcaatttgtc agacaagagt tcgatatatt cgatattgta ctctgggcga
     6421 ttttcttcga caagttggcg agcagtgata cggccctcaa gttctgagct ggcatcgatg
     6481 tctaggtaaa gcgcgcgtgt tgtttcacgg cgtgggctac gttcttttgt ttcttgataa
     6541 aaaactttgt aaatcatata gttcctttct atttacaggt cagcttattc caaactttta
     6601 gcagatattt gcttgatttc attccatttt gtgtctagat tgaccttgat tcgttacaat
     6661 tatttcaatt ataccacaaa atgaaaaatt agtaaaagac ggaaacgaga aagttagggg
     6721 acgatttctt cggtaagcgt ttgcaaaaac aaagaaaatg tgttatgttg ataacggaag
     6781 tgaagtttat tacttgtcat aattccatat agattttaag tcaaggaggt tgccctatgt
     6841 ataacttatt tgcttttgct atcggagttc gtttgctagc ttttatcgtt tttgttttgc
     6901 gtttatggag gaaatcttct atttgccaaa ctggaacgat gacaaaccaa gttcttgagg
     6961 aaaattacct ttgtgactct ctactcgctt tttctcctcc tcgtgaccta tgtcgtttgg
     7021 tttgtatttt actttggatt aaatgcttag atgccctgct tatgctgggg ttttttgttt
     7081 ggggatgtag agatagtaga tttacgacac gaaaattcca ccccatctat caagatgagg
     7141 tggtctttgc atttttctaa aatgatatga caatggaatt ttcaaagctt attattttta
     7201 tgggagtcat tgttctgctc aaaaatagag ttgaagcata aaaataaaac aatacaaaca
     7261 gataaatcga atggtaaagg gatggtagta atgttcaaat cattgagaat gctgagcaaa
     7321 ctgtaagaga tgaagacaat aaaatttatc cttctaaaaa tgtgtttctt atctagcatg
     7381 acttaccaaa ctttttacga aggtcttttc caatggtata acctgccata aataaagcga
     7441 taccaacacc tacaccaaag ccacccttga tttcttgcaa ttccttatta gaaatttcac
     7501 gacagttgtt caaatctttc atcatattaa tctcctccta aaaaataacc agctgccaaa
     7561 ccagaaccta taagtgctgt tccacctgca atagctttcc aagatactgc tactccaaag
     7621 ataaccaagg gagcgagacc gccatcaata tctgataatt cattttcaga taaggataaa
     7681 aattgattgt caagaatgtc aaaatttgtc attgaacttt cctccttttt tcttgttcac
     7741 ttttatattc ggaaaagaaa aggaaaagtg agcatttttt taaattattt ttagttaagt
     7801 gagggcactc ttgtctgggg gcaaagaaaa ttcccatgtg ccatcttttg tagtataata
     7861 gtaagcagac aaaaagatag gaatgtgtta tgaaagtatt agcttttgat acgtccagca
     7921 aggctctttc tctcgctatt ttagaggata agcaggttct tgccgagacg acgattaata
     7981 tcaagaaaaa tcacagtatt accctcatgc cagccattga ttttttgatg gagagtttgg
     8041 actggacgcc caaggatttg gaccgaatcg tggtggcgga agggccaggt agctacacag
     8101 gcttgcgaat cgcggtagcc actgccaaga ccttgactca tactctgaac attgagttag
     8161 ttggtatgtc tagcctcttg gctctggtgc catatcaaca agaaggcttg ttcgttcctt
     8221 tgatggatgc gcgtcgcaac aatgtttatg caggatttta tgaaaatgct aaacctgtca
     8281 tgccagaagc gcacctatct tttgaagagg tgctagaaaa agtcaagggt gctagtcagg
     8341 taacctttgt cggagaagtt ggcccctttg tggagcagat tcaagaacac ttgccaagga
     8401 ctaattataa agaaaccttg cctaatgcag ccaatcttgc tcttttagct tgggacaagg
     8461 aagcagactc cttgcatgat tttgtgccaa attacctcaa acgagtcgag gctgaggaaa
     8521 actggctcaa gaaccatacc gagtctggtg agtcctacat taaacgccta tgatagaaat
     8581 caagcgaatt caacaacagc ctgacctagc tcaagccatc tacgctgtta tggcagctgt
     8641 ttacctagtc agtccttgga ctctggagca aatccaagca gatctgtccc aagaccagac
     8701 ttggtatgca ttggcttatg atggggcaga agtgattgga tttctagctg tgcaggagaa
     8761 tctttttgaa gcagaagtcc tgcaaatcgc tgtcaaagga gcttatcagg gtcagggaat
     8821 tgcgtcagcc ttgtttgctc aattgccgac agataaggag attttcctcg aagtcagaaa
     8881 gtcaaatcaa cgagcgcaag cattttacaa gaaagaaaaa atggcggtca tcgctgagcg
     8941 aaaggcctac taccatgacc cagtcgagga cgccattatc atgaagagag aaatagatga
     9001 aggatagata tattttagca tttgagacat cctgtgatga gaccagtgtc gccgtcttga
     9061 aaaacgacga tgagctcttg tccaatgtca ttgctagtca aattgagagt cacaaacgtt
     9121 ttggtggcgt agtgcccgaa gtagccagtc gtcaccatgt cgaggtcatt acagcctgta
     9181 tcgaggaggc attggcagaa gcagggatta ccgaagagga cgtgacagct gttgcggtta
     9241 cctacggacc aggcttggtc ggagccttgc tagttggttt gtcagctgcc aaggcctttg
     9301 cttgggctca cggacttcca ctgattcctg ttaatcacat ggctgggcac ctcatggcag
     9361 ctcagagtgt ggagcctttg gagtttccct tgctagccct cttggtcagc ggcggacaca
     9421 cagagttggt ttatgtttcg gaggcaggag attataagat tgttggggaa acccgtgatg
     9481 atgcggttgg tgaggcttat gataaggtcg gccgtgtcat gggcttgacc tatcctgcag
     9541 gtcgtgagat tgacgagctg gctcatcagg ggcaggatat ttatgatttc ccccgtgcca
     9601 tgattaagga agataatctg gagttctcct tctcaggttt gaaatctgcc tttatcaatc
     9661 tttatcacaa tgccgagcaa aagggagaaa gcctgtctac agaagatttg tgtgcttcct
     9721 tccaagcagc agttatggac attctcatgg caaaaaccaa gaaggctttg gagaaatatc
     9781 ctgttaaaac cctggttgtg gcaggtggtg tggcagccaa taaaggtctc agagaacgcc
     9841 tagcagccga aatcacagat gtcaaggtta tcatcccccc tctgcgactc tgcggagaca
     9901 atgcaggtat gattgcctat gccagcgtca gcgagtggaa caaagaaaac ttcgcaggct
     9961 gggacctcaa tgccaaacca agtcttgcct ttgataccat ggaataaaga gtggctcttt
    10021 gtcaagtgta gtgggtagtc gaaaagctgc aatctggaga gtacgaaatt cgtactctct
    10081 tttttgatgt tcaaagtcat caaaatccgt tttttaaaat tgttaaagtt ccggaaacca
    10141 aaggctttgc gcttgataat cttaatcaaa ttattggtcg cttcaagttt agcgttggaa
    10201 taaggcagct taagtgcgtt gataatctta tctctatccc ttaaaaaagt ccaaaagacc
    10261 gtttgaaaaa gcggatgaac cgttggcagt tcttgctcaa tcaatccaaa gaaatggtcg
    10321 gcattcttct cttgaaaatg aaagagcagg agttgataga gttcgtagtg aacctgtaat
    10381 ccctcagagt aagaaagcag cttatctcgt acttcccgat gggttaagtg cattcgaaac
    10441 gtgggctgat agaatcgttt ctgacagagc ttgaagctat actggtgtag taaatcagtc
    10501 cagtggactg atttagcccg agcctagaaa cgaaaaagcg agggttccaa aagcgcttga
    10561 gcgcccgata ctccaaggat tttcggtcaa attggttcat gatttggatt cgtactcggt
    10621 tcatagctcg gctcagatgt tggacaatgt ggaagcggtc aagaacaatc ttcgcctttg
    10681 gaaagagttg cttagcgagc cgataataag ggctgtacat gtccatggtg atgacctcga
    10741 ccagctcccg aacctctctc tgatagcgtt ggaaatggtt tcgaatcacc gcatgagttc
    10801 gcccgtctaa aattgcgagg atggatttgg actcaaaatc ttgggcaatg aagctcattt
    10861 tgctcttttt gaagctatac tcatcccaac tcataacttt tggcaacttg gtccaatcgg
    10921 tttcaaactt aaattccctc agttttcgga tgacggtgga agttgagacc gccaatctgt
    10981 gggcaatctc agtcatagac tgcttttcaa ggaggagctg agcgattttt tgtctcacca
    11041 tgttggaaat ctggcaattt ttcttgacaa tggatgtttg agaaacgacc accttaaggc
    11101 aattcttgca ctgaaagcgg cgctttttga gatgcagtac cgtgggtaaa ccctgacagt
    11161 cgagaagcgg aattttagag gctttctgga agtcgtattt gatcatcttc ccttgacaat
    11221 gaggacaagg aggagcgggg gaatccaact ttgcctgaac gactagatgg gtttggtatt
    11281 tcagaacaga caagattttg atatttttgt cttccaatcc gagcaaatct gtggtattct
    11341 taagttgttc catatggacc ctttctaatg agttggttag acgcttttca ttataggtca
    11401 tatggggctt tttttctaca agaaacgacc ctataattcc tggggtggga ttacccacta
    11461 cagaaattat agagccaaag cattccaaag tcttgtctga ctctggaatg ttttctgttc
    11521 acagttgttt tgtaactgcc taataagtaa ccgcgctata acgaggtatc taccgagatt
    11581 gtcaattctc cagtatactg ttataaaaaa caaaactgga ggattttttt atgtcctccc
    11641 atcgtcccat cgactgttcc gtagctgccc aataacggag tatagtcggc tgaaacaaga
    11701 ataggacaaa agtgcctcaa gaaaagcatc gtaatttgac aatattattc tgagatgttt
    11761 ttgatgtaag cccatatttt ctcaatggga ttatactcgg gtgaataggt aggaagtggt
    11821 aacagtctat gccctgctcc ttacacatgt tcattctgtg aaaccttgca ttgtccataa
    11881 tgataaggga tggtgtatct aaagtaggta gtaagaattt ttggaagcaa gcttcgaaaa
    11941 agtcactcgt catcgtatct ttataggtca tcggagccat agtatattga aacaaaaaag
    12001 ggcattagta cttctataac agtatcgcaa tctctggtgt gcgttgtctc gatcttaatt
    12061 caaataatta tatcttcttc cagagagact aactgcctgc tcaaggctcg atcatatttg
    12121 agataaaaat aggtctcaac ccctgtctca taaatataaa taggagtcag gtagcttaag
    12181 tgattcaatt ctttaaggaa ccgatttact ttttctgggt cttgttcgca gtaggtacgg
    12241 ctctttttag actatatccc atagccttta gagcgtaatg aatagttgtt ggaggacagt
    12301 tgaattcagc agctatttca gtcaaataag catcgggatg agtttcaata tagatcttta
    12361 atttatctct atcaactttt tcaattaata gtggaagttt tcttaaagtt agtgtgttga
    12421 aacgttttta tacagtgcta aaatttgaag tgtagtgcag atgtatttgt aatagtatta
    12481 tagcaattct ttggagaagg tcgagacaag agaaaatagg tatctttgag atataagtat
    12541 gatttactat aaaattattg agttattcat aaaaatttct ctatcaaata tcataatgcg
    12601 tcgtttaagg agatggttac aatgcaatat agttgtggaa aaataaatat taatatccct
    12661 gatggatatg gagacattaa ggatatagtg ttttcggctc atattatagt taggtataat
    12721 aatggacatt gtggaggtat agatccgcat ataattggac tttgtaaaaa gcagatcaga
    12781 aggatgtctc catatcctat tttgataatc gtatctagag attcaaaggt tattgatgat
    12841 tataaaaatt tagatattgc ctatgttgat tgtactcaat gttcaaataa ttttgaaact
    12901 gccttacacg ttaaaaatat tttaaaatta ttaaaaatcc aacttataca ctgtcatggc
    12961 tactcaacta attatttttt atatatgtta aaaaaacttg acaagaatgg atttggaaag
    13021 gttaagacag tgataacatg ccatggatgg gttgaatata acttaaaaaa gaaattcttg
    13081 acttattttg atttttggac atattctatg ggagatgctt ttatttgtgt atctgaaact
    13141 atgaaaaaaa gattggagag tataataaaa aaataagaag atagttgcaa taaataacgg
    13201 aattaatgta tcaaatagcg atttagatgt agtaggtgtt caagacttta aaaaagaatt
    13261 ttgtattcca aataacaaaa aaatcatttg ttatgttgga aggttggatc cagaaaaaag
    13321 gccggataga ttccttgaat ttgcagaaaa attattttta gtcagagaag atgtgatttt
    13381 tattatggct ggaaatggta gtatgtgggc tactttgaaa gaaaaaattt gccatttgaa
    13441 atgtagagat aatttcaggt tacttggtga aatctatcca gctactatag tttaccaaat
    13501 atcggattta ttgtatattc cttctgatac agaaggaata cctatgtgtg ttttagagtc
    13561 aatgtcacaa gaaactccgg ttttagctag taatgttggc gggttaagtg aaattattga
    13621 acatagggtt gatggatttt tatttgagaa ggaagatgtt gagggagtgt gtgcttgtgc
    13681 taatttttta ctcaatgatt ctgagtattt gaaatatata ggtgagaata gtaaatcaaa
    13741 aataagaaaa catttttctg tgcaaaaaat gtttgtagaa accatgagag tatatgatga
    13801 attattagag aagagtagtc atggatagga atatagatca agaattagta agtattataa
    13861 taccaacaca taataggtat gaatctctga ttagagctgt gaaaagttgt ttacatcaaa
    13921 gttataaaaa tatcgaagtt ataattattg atgataatta tagtaatgta aatttaagaa
    13981 ataaaattat ccatcaattt ggctatacca gtcatagaat taagttaatt ttaagtaatg
    14041 aagatttagg tgcaactaat gccagaaaca taggtatcaa aaattctaga ggtaagtata
    14101 tatcattttt agacgatgat gatgaatata tgccagatcg aattttaaag ttgatggctt
    14161 gttttaaaaa gagtagaatg aagaatttag ctttagttta tagttatgga ataataattt
    14221 atccaatagg aaatatttta atttattgag tttcaacgag agaatattgg ttacaaagaa
    14281 atattattct ttaaacataa agcggttact attaatagga gacaaatgca aggctttaaa
    14341 agtaatcaag aaggcaagag aagaaaaaat ttttaacgaa tttctttttc gaaatatatg
    14401 ttattatatc attttggttt tttctattgt atatatgaca actatgttca attaaaattt
    14461 agaaagtgag aaactattgt gtatactatt ataaaatcaa atataaaaaa atttagttta
    14521 ttaacgatat ttattgttgc tggtcaatta ttgctaattt atgcagcaac tattaatgct
    14581 ctggtgttga atgaattaat tgcgatgaat ttagagcggt ttttgaaatt gtcaatctac
    14641 caaatgattg tctggtgtgg gataatattc cttgactggg tagtgaaaaa ttatcaggtt
    14701 gaagtgatcc aagagtttaa tctagagatt cgaaatagag ttgccacaga catctctaac
    14761 tctacctatc aagaatttca tagtaaatca tcaggaacat atctttcgtg gctaaataat
    14821 gatgttcaga ctttaaatga tcaggctttt aaacaacttt ttttagtaat aaaaggaatt
    14881 tctggtacta tatttgcagt tgtgactctt aatcactatc attggtcatt gactgtagcc
    14941 accttgtttt cattaatgat tatgctactt gtaccaaaaa tctttgcatc gaaaatgcga
    15001 gaagttagtc taaatttaac taaccaaaat gaagcttttt taaaatctag tgagactata
    15061 ttgaatggat ttgatgtgtt agcgtccttg aatcttttat atgtattgcc taagaaaatt
    15121 aaagaagcag gaattttatt aaagatggtt atacaaagaa agacaactgt agaaacgtta
    15181 gcaggcgcta ttagcttctt tctcaatatt ttttttcaga tatctctcgt ttttttaaca
    15241 ggctatcttg caataaaagg aatagtgaaa attggtacta ttgaagcaat aggagcacta
    15301 acaggtgtta tttttacagc gctaggtgaa ttaggaggtc aattatcctc tattattggt
    15361 acgaagccta tttttttaaa attgtattca attaatccaa ttgagtcaaa taaaatgaat
    15421 gatatcgaac caaatgaggt gaatagagat tttccgttat atgaagcaaa aaatatttgc
    15481 tataagtatg gagataaaga aatattaaaa aacttaaatt tttgttttca acgtaatgaa
    15541 aagtatttaa ttttaggtga aagtggaagc gggaaatcta cattattaaa attattgagt
    15601 ggctttttga gagattatag tggagaattg cgattctgcg gggatgatat aaaaaaaacc
    15661 tcctatttaa atatggtttc gaatgttcta tatgtagatc aaaaagctta tttgtttgaa
    15721 ggtacgatta gagataatat tttattggaa gaaaattata ctgatgaaga aatactacag
    15781 tctttagagc aagttggttt gagtgtaaaa gattttccta ataacatttt agattattat
    15841 gttggtgatg atgggagatt actgtcagga gggcagaaac aaaaaattac tttagctaga
    15901 gggctaatta gaaataagaa aatagtatta attgacgagg gaacttctgc tatcgatagg
    15961 agaacttcgt tagcgattga acgtaagata ttagatagag aggatttgac tgtcattatt
    16021 gttacccatg ctccgcatcc ggaacttaaa caatatttta ctaagatata tcaatttcca
    16081 aaggatttta tttaagaata taggggaggg aaacatgaga ttctattgtg aagcttatga
    16141 ggtaattact gaagagaaaa aagtatactt taatgatatt gagttagaag ttaagtattc
    16201 ctctgtcgaa gaattgttta taatatgtga gaaattatta gataagaaaa aagtatcatt
    16261 tttttatgta tatgagaaac ccttaaggta tctgttattt gactatatat ttctactagt
    16321 tctagctaaa aaaaatatcc caatcttaga tggagtttcc aataagcaag ttgatccaac
    16381 gttgctgcat cacttttctt tggaaattga aaagaatttt atcgattttt gctataaaaa
    16441 tatggatctc atcctaaaaa ctcaaagtat atctttgtgt catagagaag agcttattat
    16501 tgtagatgtt tcagatgact ctaaatttgg tgttttttac aagcgtttta gaacactggt
    16561 tgataaaaat aacggaaaat atgtttgtgt ttataatttc agtcgtgttt cagatatact
    16621 gcaaaactgg aaaaattatt gcaatcgaaa attttcggtt acgtttactg aaagccaatt
    16681 tgaattattt aagcttttat ataatcaaaa aaattttaaa acaatttcgt tgctatttgg
    16741 aaaaaaattg ttgctggagg aattatctat tatagcgatc ttactaatat agaatacttt
    16801 tgtatttttt ggtgggatag tatgtttggg aaagattcta ttggaaaata cgtatatgta
    16861 gaagagatta gtagatgtca ttttttagat agaaattatt ctttttgtta tggtttacaa
    16921 gattataaaa gtaaacttat taaatatttt ttagaatagt taatctattc gagagagata
    16981 aagaaatatg gaaaatactt tattgaatat cacaggaagc ttcgatatgg aaactaggaa
    17041 tctaattagt tattctttaa ctgatatctt tgaaacagat aaaataagaa ttgaacttct
    17101 tggagaaatt tattataaaa atataaagtt ggaattgcat gaattcgctg gattgtataa
    17161 gatttatgga attagcttaa taaagaatat taccggaatg tttttaatta taatttttga
    17221 tacgaagaca aaagaattaa aaatttttca agatataacg acttcatact ttaatttata
    17281 ctatactgtt tatggaggtg tgttctatat atagtacatc tttaaagaaa gtgatgaagt
    17341 tatctcatgt tcccgttacc ttaaataaca aaaaaataca agaatttatg agaaatggat
    17401 ttattttaga ttcaaatact ttagtaaccg aaattaataa attagaatat ttctcttaca
    17461 tttctgtaaa taatactctt cgtatatgtg gtattgatta taatgattca aacaatttta
    17521 ctaaagaaca agtattaaag aattgggact ctatgctacg tgaatctata ttaagagtgt
    17581 atagtgaagc aggagaggct aatattacac tatcatctgg ttttgattca aattatatat
    17641 tatatacatt agcgaattat acgaattctt caattaatgc attttgcata ggaggagaaa
    17701 aaggaattaa tgagattcct gaagtaacta aaattgcaaa attttatggt ataaatttat
    17761 tagttgatac tgtaatgagc ccaagattta gaatattttc ccgatatagt atggagattg
    17821 gaaggaagtc tctttgaatg tggtgtcata ctgcagtact atttaggcag gttgttgttc
    17881 caaaaaggga acacaagtat tctttgtggc gagtcagcgg atgaaataat gacttttaag
    17941 tatcattctg tgaactacaa tcaattttgt aatgataaac agaagtcagt atattttagt
    18001 tattccgact atccatttta tgttacaaat tcaattgttt taaagaaaaa tagcctactt
    18061 ttgcatagtt ttggcattca tcctagatat ccatataaaa tgtctgagat tgttgaaatg
    18121 tctaaaaaaa tatcagatct aaacgataaa aaagaatttc acaaaaagaa ctgtgagttg
    18181 aggtttcaag atagtgttct tgataacata aatagtgtcc cgggtacaac tcatttattt
    18241 agttgtttaa atattcaaac attagtaaaa attattttat atatttttcg atacaacagt
    18301 tgtatgaaaa tatttaattt tagagataaa gagcttatct tttttaataa gattgtaaat
    18361 gggctgatac aaaatattga ggagaattta gaggatgata ttgaaaggat attgaaatat
    18421 ttatatatat gtttatttaa cgaaatattc attattaaga ataaggtgaa tttttttgat
    18481 gatgtggaat ttaatcagac acttagtgag tttttagata aattgtagag ggaatggtta
    18541 tgagtgacaa tactaagtat atctttttat ctccacattt agatgacgca attttttcct
    18601 gtggtgatta tatttcaaaa ttaacttcag aaggagaaat tgtacttgtt attactatat
    18661 tttctggtta ccctttgagc caacagctac agccctctgc taagcaattt cataagttgt
    18721 gtaaccttgg gaaatatccg attgaagaaa ggaagaaaga agacaggtta gcttgtgaac
    18781 gtctacaatg tgattttaga cacttatcgt actatgaatg tctctatagg aaagatagaa
    18841 atggcaattt tctataccgt catatctata gtaaattaaa aaatgaggac acattaaaga
    18901 atgatatcat aaaagagctg ttaatgcatt tagacgacaa atgtgtcgta tattgtccgc
    18961 tttcacttgg tgaccatgtt gatcatgttt ttgtgaatag tattggaagg gcgcttgaat
    19021 ttatgcgtta taaagtaata tattatgagg acttcccata tgtaagtgat agtagtatgg
    19081 ttagttatat gggaaaaact aaagaattaa aaatgtatca agaggaactt gatgaaaaac
    19141 attatattga tagaatatca tcaatattgt gctataaatc tcagattttg ataatctgga
    19201 aatcagttga aaaactttta aacaatatta aagagttgta tttaaggaat ggggcagctt
    19261 attctattag attttggatt aagaaataag gaagtagttt tatgaatata gcagtaattg
    19321 gtttggggca tgttgggctg gcctacgcgt tactatttgc atctaaatat aaagttgttg
    19381 catatgatat agattctgta aaaataaata atttaaaaaa gggcactctt ccatctaaaa
    19441 atgaagagct tatgaagttt ttttgcgaga ataacttaaa tattactttt tttgatacat
    19501 tttctgaaat taaaaataat attgattatt atattattgc gcttccgaca gattatgatg
    19561 agaaaattgg tagttttaat acatatgaaa tcgaacaaac ggtatcgaag attctgaggg
    19621 taaaacctaa tggaaagatt attttaaagt caacagttcc gatcggcttt tcaaacaaat
    19681 taaaaaggct gtttgataca aaaaatatca tttttgtccc tgaatttttg agagaaggtt
    19741 gttctatata tgataattta tatccaagtc gcatagttgt tggagatgag acagttgaag
    19801 gaagaaaaat tgcagagttg ttcctttcga ttagtactca tagtactgcc aatattaaaa
    19861 atgttatgtt agtttctcct actgaagcag aagcaattaa gcttttttct aacacattct
    19921 tagctctccg tgttgctttt tttaatgaac tagattcttt tgctgagagg agaagtttaa
    19981 atgctgaagt tgtaataaaa ggtgtttgtt tagatccaag aattggaaat ttttataata
    20041 atccttcttt tggatttgga ggatattgtc ttcccaaaga tactagacaa ttaaaaaaag
    20101 aatttataga aataaatgcc ccagtgatag aagcgattga tatttcaaac acaaatagaa
    20161 aacagttcat agttaaacaa atattggaac gaaagccaaa gatagtagga atatataaat
    20221 tggggatgaa atataattca gataattaca aagagtcagc tattttaagt ataattaatg
    20281 aactattgat tgtcggtata aaaattttag tatatgaacc aaatttaaac gttagtatag
    20341 ataacgtaat ttttgaaaag aattttgaac tatttataaa acaaagtgat ctaattgttg
    20401 caaatagatg ggataggggc cttgaagctt ataaagataa agtttacaca agggggatct
    20461 ggataagaga ttaactattg atattaaaaa ggcaataatt tataaaattt gtacaaaaaa
    20521 atgttaaatt ttcacatttt catagtatac tgtttaatag aaagtaggtt ctttgtaacc
    20581 gctccattat aaaatccttt cactcttccg gtatactatt aggaaaaaca taactggagg
    20641 atattttgag ctcacacctc atcgttccag tggctgttcc ccaagctcgt gtactgccca
    20701 aaaaagttag acattctatt tagaacgagg attgagttct gtattgtaca aggctcggtc
    20761 cttttagagt cagcttaagg ctggcttttt caatcaccaa agtgtcagaa tgttttgaca
    20821 aatgaacaca aataatgata taatatgcaa aagctaggag gtggtaggat gattgaaaaa
    20881 atggaactgg gggaatttta caaggaattg cgcttggcga gaaagctcaa gcagtcagat
    20941 gtggcttgtg ctggactaac agcctctcag ttgtccaagt ttgaactagg acagtctatg
    21001 ctgtctgcag acaagctgat cctagccatc caagggatca atatgaattt tgatgagttt
    21061 gggcacaaac tcaacaacta tcaagaatct ccacatatgc gaattggtag aagggttgtg
    21121 gattgctttt cccatcagga tatagctgct ttagagcagc tattggagga agtcgatcaa
    21181 gaacagatgg cgcagaccta tcgtcgtttg aatgccattg tgattaaaaa tgcactccat
    21241 tccttagata aaagctaccc gctaacagag gaggatagcg agtttttgac tacctacctc
    21301 tacgctattg agtcttggac ctggtttgaa ctctatcttt tttgcaatac tatgcccttc
    21361 ttgagcaatc aagatctgat ctttttatca acctccttac tcgaaaaatc caaggaattt
    21421 aaagagttag tacacaatcg atggtatatg aaaagtggtt atcttaatat catctcagaa
    21481 cttatggagc gcaagctatt ttcttatatt ccaatctttg aagctgagct ggagcgcatg
    21541 ctccgtccat acgatgtttt tgaaaaagta ttgtggcagt ttttaaagaa aatgcagatt
    21601 tttcttcaaa ccaaaggaag caatcaaaaa gagattgaac actttatcca atctctgcaa
    21661 gtattagaaa atccacaatt gacagccctt tttgaattgc gtttgcagca atacaaagag
    21721 cttatcgatt agttagaaat gggaaaaaga taataatatc agcaacgatc gtcaataatg
    21781 ttaaaacttg tttcttcata ttacttccct cctcattagt aataacttta ttataccagg
    21841 gaaataatca aatctaccaa aatcgcaaat ctgaaatttc tataagaaaa aatatcaaat
    21901 atgcgatttt ctaaaataag ccaatttccg tgttatactg tccttgtaaa acatttgaag
    21961 caaatcctag gtcgcagaag tggtttacaa atgaagataa ttgaaggagt gtaaaagatg
    22021 ttaaatttac aatttgcaga aacaatggaa ttgacagaag ctgagttgca agatgttaga
    22081 ggaggcaacc tcgtaaattc tatgggaggt ggtggaagaa gtggtatatc tggttggggc
    22141 gtcccaggaa tttaccctgg ttggggcaat caagggatga gtcctaatcg tggagctttt
    22201 gattggacta tagatttagc agatggattg tttggccgcc gtagaagata ggctcttata
    22261 ggagataata ggatgaagaa aatgaaagaa gtgaaatttc acctagcaac tggcttgttg
    22321 attttgactt attacctcat ttttaatgtc acatcagact tagattttat ggttgctttg
    22381 tctgataata tgtactatgt gttccaagtt ttattggtac ttattctggg aactatagct
    22441 acaattgctt ttgtcaaaag tgaacattgg aaagagtgtg gtcgtttcca gtttcgttgg
    22501 tcttacctgg gtgttttcct tctttctttt ttcttattgt tcgtgtgggc aaatctaaca
    22561 acctatatct ttcctcgtac ccagaatgga agtacagtcg tagaagtagc caccagttta
    22621 acaggaatta gctattttgt tacgcgaata ctttatacta gtattatcgc acctgtatca
    22681 gaagaggttg tttgtcgtgg tcttttgatg acaagtttat ctaaagttaa gagatactat
    22741 cttgatgttc ttgtttccgc tgccatattt ggcgctatgc atgttttgca gtatggttgg
    22801 ataacgacag atttcataaa gtattttgga atgggcttga tattttgtat gatgtttcgc
    22861 tacacccgat ccatctattg ggctatagct ctgcatgctt catggaatag cttcttactc
    22921 attgttactt tattggtatt tggatattag aaaggtgata tatgaaaaag ataatctcac
    22981 accgctactt tattatagtt tttctactag ttattgctga ccagaagttc agtgttttag
    23041 ttttacgcag cgaccttgtt gctgggctat ctgactttgc ctattatctg tcggatatga
    23101 tgttgaattt tcttgtggtt ttatttgctc ttattgctat gatttggtcg gggaaatggc
    23161 agaaaatcaa tagtagaaag tttaaaggat cctatctttt ctattccttc ctagctctgc
    23221 ttgcttttgt tgcttggaat tttgtcacct tttttctttt cccacctact cgaaatgaaa
    23281 tttcttatca acatgctgct cctactttta caggagctac ggcatttttg atgtattttt
    23341 tttatcctgt gattgcaggt cccatttttg aagacatgat ttatcgtgga ttggtgatga
    23401 cagctctgga aaaaggaaag aaatgggggc tagatgtact tggttctgct attttatttg
    23461 gggtctcgca cattagtaat cacggttggg tcttgacaga ctttttcgtc tatatgggtg
    23521 gcggacttat atttgcagtc ttatttagaa tgacaaagtc catttattgg cctattgggc
    23581 tgcatatagt ctacaacggc attggtcagc ttttgatgtt actgtaattt tggttgttag
    23641 tagtatcgcg gtctatttct ggggaaagat tcccatttga acttaagaag gagttgtgat
    23701 gaaagtattt cttcaaaata gagattttag gcaattaact atcaaccagt ggatttcaac
    23761 gcttggggat acgatttttt atctggcctt cctgaattat gtggcagatg cgtcttttgc
    23821 ccctttggcg attttactta tcacgatttc agaaaccctt ccccaagttc tacaaatctt
    23881 tctgggagtt ttggcggatt ttcaacatca tcgtgtcttg aaatacacag tcattagttt
    23941 tacaaaattt ttgctttact ctatagtgtc cctatcgctt tcagggcagt ctttttcctt
    24001 gttgctagta acctttattt gtctgcttaa cctcttgtct gacacattga gttatttttc
    24061 aggcgccatg ctcactccga ttttcattag aattattggg caagaccatc tggcagaagc
    24121 tattggattt aaacagtcaa ctgttagttt agtgaaaaca atcagtaata tcctaggagg
    24181 agtcttacta ggcattctat ccatccagtt tatttcctta ctgaacgctc ttaccttttt
    24241 aatcgcattt ttaggtatcc tcttcataaa aactgacctc ttgaaagtag aaaaaacgat
    24301 tagctatcaa gaaggactct ctgtaaaatc cttttgccag catttgctcc aatcatcgaa
    24361 attgatatgg aatatgaata aggtgctctt ggttttgttt attatctcta ctagtcaagc
    24421 agtgataaat gttacggttc ctatttccac tctattttta aggaaccagc cctttttgaa
    24481 tttacaaact ggtcaatctc ttgccttgtt agccacacta gaattatcag cccttatttt
    24541 gggaagtctg atgagtggct atctgcaaca taccatttcc ataaaaatag ccctgtatgc
    24601 ttcactccta ctccaattac tactcctagt gggctttgcg acagctcatt ttggcttgat
    24661 tctgatcttt agctttttgg atgccttttt cgcgggtatt ctctctccta gattgcaaga
    24721 actcgtcttt aaacaaatac ctgaggagtc aatgggagca gttcaatctt ctatcggtgc
    24781 cattacggtt gttttaccta gcttatttac aatagctttg ggaaccattg ctactagctt
    24841 tggaactctg gcagttagct ttgttttatt actatttctt ctagttgcct ttgtcatgct
    24901 tctgaatatt cgtgaaagta tttagtggag aatttctata atatatgttt gagactggat
    24961 tgccagtctt tttatgatgg tcaaaatcaa cagacttttt ctcttttctg aatgtgttat
    25021 agtagactga atctaaaata gtacgaaata attgctaaaa catttataga aattaatttt
    25081 actttcccaa tcgatttgtt ctcatcttat ttcaatctgc tatataatag tccatgctgt
    25141 ggctggattc ttttcagcct acttatactc ttcgaaactc tcttcaaacc acgtcagctt
    25201 caccttgccg taggtatggt tactgacttc gtcagttcta tccacaacct caaaacagtg
    25261 ttttgagctg acttcgtcag ttctatctgc aacctcaaaa caatgttttg agcaacctgc
    25321 ggctagtttc ctagtttgct ctttgatttt cattgagtat tattaagaca atatgaggag
    25381 aaagatgaaa gaaaaaggat tttaggaggg ggcgcaggca gccatgccaa cggctcttgg
    25441 ctatgtcagt atcggcctgg cctgtgggac tatcggtgcg ccctatgtga cacctgttga
    25501 gatgggcttg atgagtctct ttgtttatgc tgggagtgcc cagtttgcca tgttggcact
    25561 gattgtggtt caagctcctg tggcagctat tgctatgacg gtttttctaa tcaacttgcg
    25621 tctctttttg ttgagtttac acgcatcgac ttatttccgt cataccagtc tttggtacaa
    25681 tatcggtatg tctagtatct tgacagatga gacctatggc gttttgatgg gtgaattggc
    25741 ccatacagac aaggtaaatc ctatgtggat gcacggaaac aatcttaaca gctatgtggc
    25801 ttggtttgtg gggacagtag tcggaacggc tctgggtggc ctgctaccaa atccagaaat
    25861 ctttggcttg gattttgccc tggttgggat gtttattggt atttttgctt cgcaatttca
    25921 gattatgcaa agacggattc ctgtccgcaa tctgctcatt atcctagcag ttgttgcggt
    25981 gtccttcttt ttgctcttga cagtggtgtc tcagtcacta gctgttctgt ttgcgacgct
    26041 acttggttgt agcatggggg tggttttaga tggtcagtaa gtatctttta ttagcagtta
    26101 ttttctctga cttggtgact tggattctcc gtatgattcc cttcatctta gtcaagtata
    26161 agggcttgcc tgcaatcgtt gagcgttttt tgaagttctt gcccgtttcc attatctttg
    26221 ccttgattct ttcaagcgta gtgacaggta aggttgggag ccttcctcaa attaaatggc
    26281 tagacttctt agccgtcttt ccaacagctt gggtagcctt tcgctaccgc aatctagtcg
    26341 gaacagttct ctttggagta gtcttgattg ccgtcttgcg tttggtcttt taaatcagcc
    26401 ataaagaaaa cctatcacag atatatatat catataatgg tgtaaatgat ttttttctgt
    26461 taagattata aggtattcta ttttggagga aatgacatga aaaaaatcgt taaatactca
    26521 tctcttgctg ccctagggct tgttgctgca ggtgtgctag cagcttgctc cggtggtgct
    26581 aagaaagaag gacaagcagc tagcaagaaa gaaattattg ttgcaactaa ttcttcacca
    26641 aaaccattca actatgaaga aaatggcgaa ttgactggtt acgagattga agtcgttcgc
    26701 gctatcttta aagactctga taagtatgat gtcaagtttg agaagacaga gtggtcaggt
    26761 gtctttgcgg gtcttgacgc tgaccgttac caaatggctg ttaacaacat cagctacact
    26821 aaagaacgtg cggagaaata cctttatgca gccccaactg ttaaagaccc taacgttctt
    26881 gtagtcaaga aagacgattc tagcatcaaa tcgcttgatg atgttggtgg aaaatcaaca
    26941 gaagttgttc aaggaacaac atctgctaaa cagttagaag actacaacaa acaacactca
    27001 gataatccaa ctatccttaa ctatactaaa gcaaacttac aacaaatcat gggccacttg
    27061 agcgatggtc agtttgacta caagatttct gataaaatca ctgttgaaac agtcatcaag
    27121 aaccaaggtt tggacaactt gaaagtcatc gatcttccaa gcgaccaaca accttacgtt
    27181 tacccacttc ttgctaaagg tcaagatgag ttgaaaacat ttgtagacaa acgtatccaa
    27241 gaactctaca aagacggaac tcttgaaaaa ttgtctaaac aattcttcgg agacacttac
    27301 ctaccggcag aagctgatat taaataattt cttgaaatca tccattctga gtaagatggg
    27361 tgatttttca gttcgctacc gcaatctagt cggaacagtt ctctttggag tggtcttgat
    27421 tgccatcttg cgtttggtct tttaaattac ccataaaaaa aacttatcac agagatagat
    27481 atcatataat ggcgtaaatg ctctttttct gttaagatta taaggtattc tattttggag
    27541 gaaatgacat gaaaaaaatc gttaaatact catctcttgc agcccttgct cttgttgctg
    27601 caggtgtgct tgcggcttgc tcaggtggtg ctaagaaaga aggacaagca gctagcaaga
    27661 aagaaatcat cgttgcaacc aatggatcac caaagccatt tatctatgaa gaaaatggcg
    27721 aattgactgg ttatgagatt gaagtcgttc gcgctatctt taaagattct gacaaatata
    27781 atgtcaagtt tgaaaagaca gaatggtcag gtgtctttgc tggtcttgat gctgaccgtt
    27841 acaatatggc tgtcaacaat cttagctaca ctaaagaacg tgcggagaaa tacctctatg
    27901 ccgcaccaat tgcccaaaat cctaatgtcc ttgtagtgaa gaaagatgac tctagtatca
    27961 agtctctcga tgatatcggt ggaaaatcga cggaagtcgt tcaagccact acatcagcta
    28021 agcagttaga agcatacaac gctgaacaca cggacaaccc aactatcctt aactatacta
    28081 aggcagattt ccaacaaatc atggtacgtt tgagcgatgg acaatttgac tacaagattt
    28141 ttgataaaat cggtgttgaa acagtgatca agaaccaagg tttggacaac ttgaaagtta
    28201 tcgaacttcc aagcgaccaa caaccgtacg tttacccact tcttgctcag ggtcaagatg
    28261 agttgaaatc atttgtagac aaacgcatta aagaactcta caaagacgga acgcttgaaa
    28321 aattgtctaa acaattcttc ggagacactt atctaccggc agaagctgat attaaataat
    28381 ttcttgaaat catccattct gagtaagatg ggtggtttct cagtttttag ggatatagtt
    28441 ttaaactata tatctgacta tctaataaca atttgtgaaa tcaaacaaat tgtgagatac
    28501 tagtacggta ttatttttaa ggagaaagaa tcatgaaaat caaaaaatgg cttggcctag
    28561 cagcccttgc tacagtcgca ggtttggctc ttgcagcttg cggaaactca gaaaagaaag
    28621 cagacaatgc aacaacgatc aaaatcgcaa ctgttaaccg tagcggttct gaagaaaaac
    28681 gttgggacaa aatccaagaa ttggttaaaa aagacggaat taccttggaa tttacagagt
    28741 tcacagacta ctcacaacca aacaaagcaa ctgctgatgg cgaagtagat ttgaacgctt
    28801 tccaacacta taacttcttg aacaactgga acaaagaaaa cggaaaagac cttgtagcga
    28861 ttgcagatac ttacatctct ccaatccgcc tttactcagg tttgaatgga agtgccaaca
    28921 agtacactaa agtagaagac atcccagcaa acggagaaat cgctgtaccg aatgacgcta
    28981 caaacgaaag ccgtgcgctt tacttgcttc aatcagctgg cttgattaaa ttggatgttt
    29041 ctggaactgc tcttgcaaca gttgccaaca tcaaagaaaa tccaaagaac ttgaaaatca
    29101 ctgaattgga cgctagccaa acagctcgtt cattgtcatc agttgacgct gccgttgtaa
    29161 acaatacctt cgttacagaa gcaaaattgg actacaagaa agcacttttc aaagaacaag
    29221 ctgatgaaaa ctcaaaacaa tggtacaaca tcattgttgc gaaaaaagat tgggaaacat
    29281 cacctaaggc tgatgctatc aagaaagtaa tcgcagctta ccacacagat gacgtgaaaa
    29341 aagttatcga agaatcatca gatggtttgg atcaaccagt ttggtaataa gaaacaggga
    29401 ggtgggagag aaaattccac ctcttgcttt tgtatagagt atagattgta aagaagacta
    29461 ttcgttcata gaaaggtaga gagaatatgg tttttcctag cgaacaagaa cagattgaaa
    29521 aatttgaaaa ggatcatgta gtccaacatt attttgaggt tttgcgtacc ttgatttcta
    29581 agaaatcagt ctttgcccag caggttggac tcaaggaagt cgcaaattat ctgggtgaga
    29641 ttttcaagcg tgttggagct gaagtggaga ttgatgagag ctatacagcg ccctttgtca
    29701 tggcacattt caagagttcg cgtccagatg ccaagacctt gattttctat aaccactatg
    29761 acactgtgcc agcggatggg gatcaggtct ggacagagga tccttttacg ctttcggtcc
    29821 gcaatggctt catgtatggg cgtggggttg atgacgacaa gggtcatatc acagctcgct
    29881 tgagtgcttt gagaaaatat atgcagcacc atgatgattt acctgtcaat atcagcttta
    29941 tcatggaggg agcggaggaa tcggcttcaa cagacctaga taagtatttg gaaaagcatg
    30001 cagacaaact ccgtggggcg gatttgttgg tctgggaaca agggaccaaa aatgccttgg
    30061 aacagctgga aatttctggt ggcaataagg ggattgtgac ctttgatgcc aaggtaaaaa
    30121 gcgctgatgt ggatatccac tcgagttatg gtggtgttgt ggaatcagct ccttggtatc
    30181 tcctccaagc cttacagtct cttcgtgctg cggatggccg tatcttggtt gaaggcttgt
    30241 acgaagaagt acaagagccc aatgaacgag aaatggcctt gctagaaact tatggtcaac
    30301 gaaacccaga ggaagttagt cggatttatg gattggagtt gcctctctta caggaggagc
    30361 ggatggcctt tctaaaacgt ttctttttcg agccagcgct taatatcgaa ggaatccagt
    30421 ctggttatca aggtcagggt gttaagacta ttttacctgc agaagccagt gccaagctag
    30481 aggttcgtct ggttccgggc ctagaaccgc atgatgttct ggaaaaaatt cggaaacaac
    30541 tagacaaaaa tggctttgat aaggtagaat tatactatac cttgggagag atgagctatc
    30601 gaagcgatat gagcgcacca gccattctca atgtgatcga gttggccaag aaattctatc
    30661 cacagggcgt ttcagtcttg ccgacgacag cggggacagg acctatgcat acggtctttg
    30721 atgccctaga ggtaccaatg gttgcatttg gtctaggaaa tgccaatagc cgagaccacg
    30781 gtggagatga aaatgtgcga atcgctgatt attacaccca tatcgaatta gtagaggagc
    30841 tgattagaag ctatgagtag agatattatc aagttagatc agatcgatgt gacttttcac
    30901 caaaagaaga gaaccatcac agcggttaag gatgtgacca ttcacatcca agaaggggat
    30961 atctacggaa tcgttggata ttctggagca gggaaatcaa cccttgtacg ggtgattaac
    31021 ctcttgcaaa aaccatctgc agggaaaatt accattgacg acgatgtgat ttttgatggt
    31081 aaggtcacct tgacggcaga gcagttgcgt cgtaaacgtc aagatatcgg gatgattttc
    31141 cagcatttta acctgatgag ccaaaagaca gcagaggaga atgtagcctt tgcccttaaa
    31201 cactctggac tcagcaagga agaaaagaag gctaaagtag ctaagttgtt ggacttggtt
    31261 ggtttggcag atcgtgctga aaactaccct tcacaactat ctggagggca aaaacagcgt
    31321 gtggcaattg cgcgtgcctt ggccaatgat ccaaaaatct tgatttcaga cgagtcaact
    31381 tctgcccttg atccgaagac aaccaagcag attttggcct tgttgcaaga tttgaaccaa
    31441 aaattaggct tgactgttgt cttgattacg catgaaatgc agattgtcaa agacattgcc
    31501 aaccgtgttg cagttatgca ggatgggcat ttgattgaag agggtagtgt gcttgaaatc
    31561 ttctcaaatc ctaaacaacc tttgactcaa gactttatct caacagctac aggtattgac
    31621 gaagccatgg tcaaaatcga gaagcaagaa atcgtggaac acttgtctga aaacagtctc
    31681 ttggtgcaac tcaagtacgc tggagcttca acagacgagc cacttttgaa tgaattgtac
    31741 aagcattacc aagtaatggc taatattctc tatgggaata tcgaaattct cgatggtact
    31801 cctgttggag aattggtggt ggtcttgtca ggtgaaaaag cagcgttggc aggtgcccaa
    31861 gaagccattc gtcaagcagg tgtacaacta aaagtattga agggaggaca gtaagatgga
    31921 atcattgatt caaacctatt taccaaatgt ctataaaatg ggttgggctg gtcaggcagg
    31981 ctggggaacg gctatctact taactcttta tatgacagtt ctttccttca ttatcggagg
    32041 cttcttgggg ctagtggcag gtctctttct cgtcttgaca gcgccaggtg gtgtcttgga
    32101 gaataaagtc gtattctgga ttttagacaa aattacctca atttttcgtg cagttccctt
    32161 tatcatcctc ttggcaatct tgtcaccact ttctcacttg attgttaaaa caagtatcgg
    32221 gccaaatgca gcccttgtcc cactttcttt tgcagtcttt gccttctttg cccgtcaggt
    32281 gcaggttgtc ttggctgaat tggatggcgg tgtcattgag gcggctcaag cgagcggagc
    32341 gactttctgg gacatcgtgg gtgtttacct atcagaaggt cttccagatt tgatccgtgt
    32401 gacgactgtg accttgattt cccttgttgg ggaaacagct atggccggtg cggttggagc
    32461 tggtggtatc ggtaacgtag ccatcgctta tggatttaac cgctacaatc acgatgtgac
    32521 catcttggca accatcatta tcattttgat tatctttgca atccaattct tgggagattt
    32581 cttgactaag aaattgagcc ataaataaaa aagagccgcg tggctctttt taactgatca
    32641 gattttctgt gcaaattttt tactcaaggc ttgtccaatc aaggcaccca ctagggctcc
    32701 gatgacaata cttgcgataa atagaaggac agttccaggg tttggagcga ccatgatgcg
    32761 gtcgatatat tcttgggatt ttcctcttgc cagaagagta gccatatagg ctttgggcgc
    32821 aatccacata agcaagattg gtcctgttgt actaaaggcg aaaataatga aagaaaggaa
    32881 gttctttgtt ttgtccttgt attttcctaa atgagctact ccatctgcta ggaggccaca
    32941 gataattcca ggaaggaagg aaccagcacc gtgtttagtt cccaagaaaa agagggcaat
    33001 gacaaggccg atagtggtaa tggctccaaa gcgcggaact tttgcgacta ggatcatata
    33061 gacgctaccg ccgacaaggg cagtaaaggc aggcgcataa aacatgtttc cagtttggtc
    33121 aaagagattg cccaaaagga caccaatccc catgcagagg aagtaaagaa ctgcaaaaag
    33181 cagtgtagtt aagatagatt tcttcatgaa ttgtctcctg ataatttttt cacaattctc
    33241 attttaccat ggtttggtgg gattgtaaat ggatactaga agtttttgaa aacgcttgaa
    33301 atatgatata atggtttcat agttattttt aggggaatat catgggtaga tttttagact
    33361 ttgtctttaa tcgtttcttt ttagggatga ttgcgacagc cttcttttgg ctattaactt
    33421 tagcaggagg gattatcctt ggtctagcgc cggctagtgc caccttgatg agcttatatg
    33481 cagaacatgg ttatagcttt cgggaataca gtttgaagga ggcttggtct ctttacaagc
    33541 aaaattttgt ctcaagcaac ctgattttct atagcttttt aggtgtgggt ctagttttga
    33601 cctatggttt gtatctcttg gtgcaattgc ctcatcagac tattgttcat ttgattgcga
    33661 cccttttgaa tgtcctagta gttgccctga tctttttggc ttatacagta tctttaaaat
    33721 tacaagttta ttttgccttg tcctatcgaa atagtctcaa attatccttg attggcatct
    33781 ttatgagtct agcagctgtg gccaaggttc tccttgggac tgtgctactt gtagcaattg
    33841 gttactatat gcctgccctg ctattttttg taggaattgg gatgtggcat ttctttatca
    33901 gtgatatgtt ggaacctgtc tatgaaatca tccatgaaaa attggcgaca aaatagaatg
    33961 aagcagtttt ggctacatac gcttctaaga acctatagtt cagtgatgat cattatcatt
    34021 gcgagttttg caatcttact ctcttacgct gactgggatt cacgtgaaaa ggaagcccag
    34081 agagtagccc agcgtgtaac tgctagaaca gtgagtgaaa ttgaatatta ccatagagag
    34141 tcaacccaga tagctcaggc tttagttgaa aatcaagctc gtattgaggg aatctataaa
    34201 tactttagcc ttagcatgcc agactatttt tactggcaat tagagcggaa agcttcgcct
    34261 tatatatcag tctctctgta tgaaaatgtt gatgacctct atgttcgaaa tgattttgta
    34321 actggggtgg ccattgcttt tcaagattac aaggaagtct atgtttctac taaagacaaa
    34381 cgtagtggag aaaaaatcag ggctgaggat ttcaaaccag caggaaatag ttttgccatt
    34441 ccggtgtcag atccagtgtc agatcaagat ttaggagtga tttacatctc cttggatcct
    34501 gctgttttat accatgccat tgataatact agaggtcata ctccgatggc agtaacagtg
    34561 acctcacctt ttgatacgga gatttttcat attggtgaga cagttgatag ggagagtgaa
    34621 aattggctag ttggcttaac ttctcatgga tatcaggttc aggtggcagt tcctaaaaac
    34681 tttgttttac aaggaacagt gactagctct gctttgattg tgggtttgag ccttctcttt
    34741 attgtcattc tttatctgac tttgaggcag acttttgcta attaccaaaa gcaggtagtg
    34801 gatttagtgg aatccattca agtcattgct caaggcgaag aggggcgtcg gattgacatt
    34861 tccgaaaaag atcaggaatt actcctaatc gcggagacga ccaatgatat gttggatcga
    34921 ttggaaaaga atatccatga tatttaccag ttagagctta gtcaaaaaga tgccaatatg
    34981 cgagccttgc aggcgcaaat caatcctcat tttatgtata atacgctgga gttcttgcgc
    35041 atgtatgcag ttatgcagag tcaagatgag ttggcagata tcatttatga attcagtagt
    35101 ctcttgcgta acaatatttc cgacgaaaga gagaccctcc tcaaacagga attagaattt
    35161 tgccgtaaat acagctatct ctgcatggtt cgctatccca agtccattgc ctatggtttc
    35221 aagatagatc cagagttaga gaatatgaag attcccaagt ttaccttgca accgctggta
    35281 gaaaactatt tcgcgcatgg tgttgaccac aggcggacag ataatgtgat tagcatcaag
    35341 gctcttaaac aggatggttt tgtggaaatt ttggtggtcg ataatggtag aggaatgtcg
    35401 gctgaaaagt tggcaaatat ccgagaaaaa ttaagtcaga aatattttga acaccgagcc
    35461 agctacagtg atcaaaggca gtctatcggg attgtcaatg tacacgagcg ttttgtgctc
    35521 tattttggag accgctatgc cattacgata gagtctgcag agcaagccgg tgttcagtat
    35581 cgtattacaa ttcaagatga gtagaaaggg agaaaatgta taaagtatta ttagtagatg
    35641 atgagtacat ggtgacagaa ggtctgaagc gtttgattcc ctttgataag tgggatatgg
    35701 aggtcgtcgc aacagccagt catgccgatg aagctctaga atatgttcag gaaaatcctg
    35761 tcgatgtcat catttccgat gtcaatatgc cagacaaaac agggcttgat atgattcggg
    35821 agatgaaaga gatcttacca gatgctgcct atatcctgct ctcaggttat caggagtttg
    35881 attatgtaaa aagagcaatg aaccttagtg tggtggacta tttggtcaag cctgttgata
    35941 aggtagagct gggaaatctg ctggagaaga ttgcaggtca gctcggcgag agagggaaga
    36001 aaagtcagac tcttagtcaa gaattagacg aggctggatt tgttagttat ttaggggata
    36061 aggagaattg gtggataggt ctatccaagg aaaaacaagg ttccttcacc attccctact
    36121 atgtcttggg ccaagactgg cagattttca tttctgacca acccctagat ggtttagtcg
    36181 ttacaccttt tgaagctcct tatcaagaac actttgaacg ctggaagctg aatgctgaga
    36241 aaaccctctt ttacggttct gtaaatttgc agcagtctga gagtctcttt gcctattacg
    36301 aaccgattta tagggttatc attcagggaa atctcaatca aatcgtagaa gagttaaatc
    36361 tcttggagaa ggtagttctt gaaaatacgc cgcgtgttcc gattactaaa cagcttttta
    36421 ttcagtttgt catggatgtt ttccatttat ttgaacatct caaagctgat gacctgacag
    36481 acatcgtcaa aaccattcat gctattcaat ccttcgatga attggttcct tatatcaagg
    36541 aaactctgag cagctttttc ggtcaatacc gtatgaatga aaatgtggtc agtgtgctgg
    36601 aagtcattgg ttgtgattac caaaaagagc tttccctcaa ggatatcagt aaggctctct
    36661 ttatcaatcc tgtctatcta gggcagttga ttaagcgtga aaccgattcg acttttgcag
    36721 agttactaaa caaacaacgt attaaggctg cccaacaact tttgctttca actagtgaca
    36781 gcatcgaaga tatttgttat gctgttggtt acagtaacct tggatatttc tataaagttt
    36841 tccgaaaatt gtgcggaaaa tcgccaaaag cctaccgaaa acaggtagaa actatactat
    36901 aagatttgta ttcctttaca aaatgtgcta taatataaat attattatta ggaggttcta
    36961 tcatgaaaaa gaaaccaatt tatctatggg tcttgctaat cttgtctgcc cttatttcag
    37021 ttccgtctct gtttggaatt gtgagtccct tgcctagtaa agaagccctt cgtactgctc
    37081 agaaacaagt tgcaggggtc aatgctcagc aattagaaga ccagcttaat tatacctata
    37141 gagtagcaga agcatctcat tctattttta atgttgcttt gattgtgcta tctactattt
    37201 tagtggtcgt agcgattgtc ttccttgttc gtaaaaattt gcaatatgca aactatactt
    37261 acgttggcta tgttttgtta gctattattg gttcgattta tggctatgtt ggtttacaag
    37321 acgctgtgca gttggttcaa gatgagagca tgcgtttgac agtgagtatt ggttcaaaag
    37381 ctgttagcat tttctatatc gtcatcaatg ttctcttcct agcccttgtc ttctataaga
    37441 tgtggcgaca acagaaagcc tcggcagaag aagaggaaac agaagagctt gcctaagtat
    37501 tgacaaaaaa gaactatcaa gatacaatct tggtagttgt tttttgatta tagataaaat
    37561 catggaggta catatgaaga taatttcttt agtttatatt agtttgagtg gcaacactga
    37621 aagttttgtg acgcgcttga aagactatct cttgtcccag tacaaaggga ttgaggttca
    37681 aaagattcat atcaaggatt tagtcaagga aggcaaaaat ttctatgaaa tggaccatcc
    37741 ctatgtcgct tttttgccga cctatctcga aggtgggaat ggcgtggata acggagatgt
    37801 tgagattttg acgacaccgg tgggagattt tattgcctat ggtaacaatg ctagtaagtg
    37861 ttttggtgtg gttgggtcag gaaatcgtaa ctttaataac caatactgcc taacagccaa
    37921 gcaatacagt caacgctttg gctttcctgt attggctgac tttgaaatgc gaggcatgct
    37981 ggaagatatc aaacatgtcg cagctattat cgcagatttg tatgagttgg aaaaggagaa
    38041 ttaatactca atgaaaatca aagagcaaac taggaagcta gtcgcaggtt gctcaaagca
    38101 cagctttgag gttgcagata gagctgacgt ggtttgaaga gattctcgaa tagtataaaa
    38161 ttcttataag aggtggttga agttgttcaa ctgttttttg agtataaaca gtctttaaga
    38221 acgtaaaaaa gcataagttc aggtcttcaa aaccttgttc ttatgctttt tatcatagaa
    38281 atatttgctg aattttctct tgaaatgaaa ccttatcttc atctcgcgct tgtcccttac
    38341 cctgcttttc cgattgcgag tgcgtagata aagaagatgg cgaagccaaa gaggaaaatc
    38401 aatcccgcaa tggcaaggtg tttgagccaa gaaggaagat ttttgttttc acgcgttacc
    38461 aaggcgtaat tcaaaagagc aaagaaaggt gttgtcagga aagagccaat catggcaaag
    38521 cggagcatgg ttgaaacctg accagagaag aacttgataa tgacgatacc gatgatagca
    38581 gtgatggtca tccagatgtt caaagattta cgattgtcct ctttttgact gattagcagt
    38641 cggagagatt cctgattaac gcgagaatag ccatcgataa cagttataac tgttccaaag
    38701 atacagagga aggcaataaa ggtaatcaag taacgggacc attcgccaag aacagaggca
    38761 tacatgccca cgaattgaga gatgtatttg gctgaagcag cttcaaccgc ctgccctgta
    38821 ggatactgaa tcagtgctcc cagtgccaca aagaagacgg ctaggatagc tgttccaata
    38881 taaccagtgt taaagtcaaa cagagcgtct tctgtgttaa agttgacggt ctttctcttt
    38941 tcagctgacc aaagtgaatt gatggctgaa atttcaatag gagccggcat ccatcctagg
    39001 agggagacga tgaagggcag agctgccatt tgccaaggtg tcttctcgac aaaatcagaa
    39061 ctgtattctg gatgcttgac cgccgcaatg ataactgcca gaacagtcgc aatggttaag
    39121 gcagacataa tccatttgac catgccgtct aaaagtttgt agcctccaaa gagtagcata
    39181 gcccaaatga ttgcaacgag aatgagggac cactgagtaa tgctaagtcc aatcattggg
    39241 aaggcactgg cgatgatagc tgagcacaga atggcaacac cagccgtgtt gaccatagcc
    39301 gaaaagacat tgaggataaa gaaaatccag agatagagtt ttcctttttc ggcataacct
    39361 tcaaccaaag tctttccagt atcagctgtg tattcagcac caaaacggaa aaatggatat
    39421 ttaaagacat tggctaagat gaccaagaga agtagagacc aaccgtaaga accgccagct
    39481 tgagttgagg atacaatgtg ggaacctcca acagcggcag ttgccattag gattccaggt
    39541 cccattgctt ttagcttgct tgcccaggtt gattgattta aggaaatagc ttgcgacatg
    39601 ataaatactc ctttttgaat tttcagaata atctgtatat gtaatctata ttctacaaaa
    39661 aattttggaa aaatgcaaga atattttgaa aaaagataga aaatttacaa agaaaat
//
LOCUS       DAVBIC010000015        38638 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.015, whole genome shotgun sequence.
ACCESSION   DAVBIC010000015 DAVBIC010000000
VERSION     DAVBIC010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 38638)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38638)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38638
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.015"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            186..632
                     /gene="rplM"
                     /locus_tag="VQ664_000741"
     CDS             186..632
                     /gene="rplM"
                     /locus_tag="VQ664_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HET2788935.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISGLI"
     gene            652..1044
                     /gene="rpsI"
                     /locus_tag="VQ664_000742"
     CDS             652..1044
                     /gene="rpsI"
                     /locus_tag="VQ664_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HET2788936.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            1393..1602
                     /locus_tag="VQ664_000743"
                     /pseudo
     CDS             1393..1602
                     /locus_tag="VQ664_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1758..2096
                     /locus_tag="VQ664_000744"
     CDS             1758..2096
                     /locus_tag="VQ664_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000176371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HET2788937.1"
                     /translation="MTLTIHVYYKGDGDCAIKFAREMLESGLVAEIRCQKGNLKYEYF
                     LPIEKEGIILLIDQWINQEALDEHHQSNTMQKILDLRKKYHLQMQVERYIEDDSGMPE
                     SDKSFIDTGN"
     gene            2286..3722
                     /locus_tag="VQ664_000745"
     CDS             2286..3722
                     /locus_tag="VQ664_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HET2788938.1"
                     /translation="MTTFKDGFLWGGAVAAHQLEGGWQEGGKGISVADVMTAGRHGVA
                     REITLGVLEGKYYPNHEAIDFYHRYKEDIALFAEMGFKCFRTSIAWTRIFPKGDELEP
                     NEEGLQFYDNLFDECLKNGIEPVITLSHFEMPYHLVTEYGGWKNRKLIDFFARFAEVV
                     FKRYKDKVKYWMTFNEINNQANYQEDFAPFTNSGIVYEEGDNREAIMYQAAHYELVAS
                     ARAVKIGHEINPDFQIGCMIAMCPIYPVTCNPKDILMAMKAMQKRYYFADVHVLGKYP
                     EHIFKYWERKGISVDFTDQDKEDLLGGTVDYIGFSYYMSFAIDSHRENNPYFDYLETE
                     DLVKNNYVKASEWEWQIDPEGLRYALNWFTDHYHLPLFIVENGFGAIDQVAADGMVHD
                     DYRIEYLGAHIREMKKAVVEDGVDLMGYTPWGCIDLVSAGTGEMRKRYGFIYVDKDDN
                     GKGSYNRSPKKSFGWYKKVILSNGESVE"
     gene            3774..4013
                     /locus_tag="VQ664_000746"
     CDS             3774..4013
                     /locus_tag="VQ664_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SemiSWEET family sugar transporter"
                     /protein_id="HET2788939.1"
                     /translation="MIGSIAAILTTFAFLPQVFRVVKTKDTGSIALGMYVMQVIGIAL
                     WLAHGIRIGDLPLILANSVSFLLSGIILFYKLKYK"
     gene            4143..4457
                     /locus_tag="VQ664_000747"
     CDS             4143..4457
                     /locus_tag="VQ664_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003037418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HET2788940.1"
                     /translation="MAKALIICAAGMSSSLMAQKTTEFLKGKGKDIVVDAISATEGGK
                     AIAAAAFDLYLVSPQTKMYFKQFEEAGSKAGKPVVQIPPQAYIPIPMGIEKMANLILE
                     NI"
     gene            4575..6554
                     /locus_tag="VQ664_000748"
     CDS             4575..6554
                     /locus_tag="VQ664_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HET2788941.1"
                     /translation="MNVLNIKEKDILQFLIKNKERFVTSKELAEYLSCSDRTVRNVLK
                     LIEKTMIIQGVRLISKQGQGYQIFFENQGAYQEFRQTYELEEDYTKTAVSKGDDRLVF
                     ILNKLLFEQVPVLFDDLADELYVSRSTLSHDFRKIRVMLSEYNLSIESRANKGVYVSG
                     EERDKRRFIINYFLENQFFKTIHCYVKFNFFAQTVPLEEFARIVLDECQEANLKLSDF
                     VLQNLVVHIALSVIRLKSGFEIKNIDCQMTDDAIERKVAQRILSKVREVTNQEFPVQE
                     IDYITLHLLAKSQQCQKNQKNISEEVLKKSLFKTFQNLGLDDMYNFSSDFQLIEGLIT
                     HLMTLQVRLESRITLNNPLVDEIKQNYSDIFFMTREILANMDKFLEWTISDDEVAYVS
                     LHFLAAMERSKESTKFNILAICATGFGAAQMLRNRLETEFGKRVEVVDVIGYYELNQE
                     KLKGIDFIVSAVDLSNLYFQIPVFKVSVFLKSDEMEMIRKAMDQMQVSSYVQSSKINK
                     FENNSFRQYFSKENFLICTESDKVNLLEKMVESLSVGESNEFEQSLLYGIKQREELSS
                     VVFSEKIAVPHPIQPFGTEGKVSVAICKDSLLWDNQSSYVQLVFLLSPSIYGNEGLAT
                     VTKKIVSLTENDELQNQLISCNNFEDFISIFEKIK"
     gene            6564..6878
                     /locus_tag="VQ664_000749"
     CDS             6564..6878
                     /locus_tag="VQ664_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HET2788942.1"
                     /translation="MNQEELQVAAFEIILHSGNARSEIHEAFAKMREGSFDDAESKLN
                     QSNEIILEAHHAQTKLLQEYASGVEIKIEIIMVHAQDHLMTTMTLLEVAKEMLALYKK
                     VN"
     gene            6909..7415
                     /locus_tag="VQ664_000750"
     CDS             6909..7415
                     /locus_tag="VQ664_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2788943.1"
                     /translation="MDKKERQKIEQQRREMALTNTFFNRYLLLRYSIALFFFGNIYWL
                     LNQFINPSPIIIFPIMLIVFSILATVEQFKLYGNRKEKLGITLMFVRIQILISIGLLV
                     LTWTSWFKNLFPIFENNQVARLFVFVVLLLGLVLSLLDIRRIKKIYKRTDKAYQQFVQ
                     LEKNSLSL"
     gene            7495..8841
                     /gene="celB"
                     /locus_tag="VQ664_000751"
     CDS             7495..8841
                     /gene="celB"
                     /locus_tag="VQ664_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HET2788944.1"
                     /translation="MDQQNGLFGFLENHVMGPMGKLAQFKVVRAITAAGMAAVPFTIV
                     GSMFLVFSILPQAFSFWPIVADIFSASFDKFTSLYMVANYATMGSLSLYFVLSLAYEL
                     TKIYAEEEELNMNPLNGALLALMAFVMTVPQIIFDGGMMKTVTSLKEGAVIADGWAMG
                     NGVARFGTTGIFTAIIMAIVTVLIYRMCVKHNWVIKMPEAVPEGVSRGFTALVPGFVV
                     AFVVIFINGLLVAMGTDIFKVIAIPFGFVSNLTNSWIGLMIIYLLTQLLWIVGIHGAN
                     IVFAFVSPIALANMAENAAGGHFAVAGEFSNMFVIAGGSGATLGLCLYIAFASKSEQL
                     KAIGRASVVPALFNINEPLIFGLPIIYNPALAIPFILAPMVTATIYYVANSLNFIKPI
                     IAQVPWPTPVGIGAFLGTADLRAVLVALVCAFAAFLVYLPFIRVYDQKLVKEEQGI"
     gene            9221..9397
                     /locus_tag="VQ664_000752"
     CDS             9221..9397
                     /locus_tag="VQ664_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2788945.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFKSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALALGMT"
     gene            9807..12020
                     /locus_tag="VQ664_000753"
     CDS             9807..12020
                     /locus_tag="VQ664_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-xylosidase"
                     /protein_id="HET2788946.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSQTGSFEDRTTQLIYNRDFGQ
                     VSLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDKADGAISLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSTPLLPRYALGNWWSRYWPYTSDEYLDLIDRFETEKIPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNRNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQIAKRLGLNVELEEPAIFDFFNPSFREAYFKDVHYELEKQGVDFWWIDWQQGTQ
                     GMLDPLWLLNHYHYQDSCKNAEGGLILSRYAGPGSHRYPVGFSGDTIISWNSLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVKTHEEGAPLISPIYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLTFQSAKVDVWFPEGEWYDFFSEKKYTGGVKLSVYRDISTT
                     PVFAKSGAIIPLVGSEIGMGVDLPEVVDWYVFPGKQHFFEMLEDQNGQRYKTRLSIDW
                     EMGMVELALQGDSSIVPSNRKHRIHFKGTNVSIIELPNKNDTAKFEWKDNKRTSLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLLEMIFTSQN"
     gene            complement(12242..12718)
                     /locus_tag="VQ664_000754"
     CDS             complement(12242..12718)
                     /locus_tag="VQ664_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HET2788947.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINAFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLKDQKSGPLGKRIEWNFAKFLIGRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            12941..16141
                     /locus_tag="VQ664_000755"
     CDS             12941..16141
                     /locus_tag="VQ664_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
                     /protein_id="HET2788948.1"
                     /translation="MQTKTKKLIVSLSSLVLSGFLLNHYMTVGAEETTTNTIQQSQKE
                     VQYQQRDTKNLVENGDFGQTEDGSSPWTGSKAQGWSAWVDQKNSADASTRVIEAKDGA
                     ITISSHEKLRAAVHRMVPIEAKKKYKLRFKIKTDHKVGIAKVRIIEESDKDKRLWNSA
                     TTSGTKDWQTIEADYSPTLDVDKIKLELFYETGTGTVSFKDIELVEVADQPSEDYQTD
                     KQLEEKIDLPIGKKHVFSLADYTYKVENPDVASVKNGILEPLKEGTTNVIVSKDGKEV
                     KKIPLKILASVKDAYTDRLDDWNGIIAGNQYYDSKNEQMAKLNQELEGKVADSLSSIS
                     SQADRTYLWEKFSNYKMSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSMEW
                     MHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDPE
                     HFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGFY
                     QDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKNPIDKDKMQTMYHWIDKSFAPL
                     LVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQS
                     DSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRTSYLSAFNKMDKTAMYNAEKGFGFG
                     LSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTET
                     DAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFLG
                     SNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDSK
                     KNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYML
                     IPNVGRATFNQMIKELERSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVLK
                     RGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKLEQAAQPQVQNSKEKEKSEEEKNH
                     SDQKNLPQTGEGQSILASLGFLLLGAFYLFRRGKNN"
     gene            16521..16906
                     /gene="tnpA"
                     /locus_tag="VQ664_000756"
                     /pseudo
     CDS             16521..16906
                     /gene="tnpA"
                     /locus_tag="VQ664_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005816675.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(17285..17914)
                     /locus_tag="VQ664_000757"
     CDS             complement(17285..17914)
                     /locus_tag="VQ664_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HET2788949.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSTLSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYITLR"
     gene            complement(17924..18925)
                     /locus_tag="VQ664_000758"
     CDS             complement(17924..18925)
                     /locus_tag="VQ664_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HET2788950.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITIAIGQEVRAILLLLLEEAKRRGI
                     VVSMDLNLRTKMISVLEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKEAYGFKAIFHTLRSSDEQDKNVYQAYALEERFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            complement(18956..19597)
                     /locus_tag="VQ664_000759"
     CDS             complement(18956..19597)
                     /locus_tag="VQ664_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HET2788951.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKDYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            complement(19616..20431)
                     /locus_tag="VQ664_000760"
     CDS             complement(19616..20431)
                     /locus_tag="VQ664_000760"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HET2788952.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIEAYREVGIEAHGYVCDVTDEDGIQAMVKQIEQEVGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
     gene            20702..21130
                     /locus_tag="VQ664_000761"
     CDS             20702..21130
                     /locus_tag="VQ664_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET2788953.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPVKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAAQGGVVNGKELFSTDAEEEDFESGI"
     gene            21142..22332
                     /locus_tag="VQ664_000762"
     CDS             21142..22332
                     /locus_tag="VQ664_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HET2788954.1"
                     /translation="MIKKVTIEKIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELDHHDLGFLYTPSCMAEYKINGDGEAREATLKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSAQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEHYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            22343..22834
                     /locus_tag="VQ664_000763"
     CDS             22343..22834
                     /locus_tag="VQ664_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HET2788955.1"
                     /translation="MTMPNIIMTRIDERLIHGQGQLWVKYLACNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKDVKDALTLVEGGVPIKE
                     INIGNIHNAPGKEQVTRSIFLGEEDKAALKELSQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            22849..23628
                     /locus_tag="VQ664_000764"
     CDS             22849..23628
                     /locus_tag="VQ664_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HET2788956.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTANHVVEEEAHDDWI"
     gene            23615..24433
                     /locus_tag="VQ664_000765"
     CDS             23615..24433
                     /locus_tag="VQ664_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET2788957.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGEDQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPAKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVVIGIIGSWLKIIA"
     gene            24433..24726
                     /locus_tag="VQ664_000766"
     CDS             24433..24726
                     /locus_tag="VQ664_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HET2788958.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQTEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIKDDLVSLQIAKGVVIYVEKESVMGKTKELLFK"
     gene            24748..26649
                     /locus_tag="VQ664_000767"
     CDS             24748..26649
                     /locus_tag="VQ664_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HET2788959.1"
                     /translation="MKEERRQFFERVDGNQCRDYILSHCSKDYEKVKSSLERLMDNRF
                     MFDSPWDMEPCSKIHQIQPMVWDQVFEDDPEWAYMLNRQEYLLQFMIGYVVEGDKDYI
                     QKCKFFLFDWIEQVREFSPQSLMTRTLDTGIRSFTWLKLLLLLLKFDMLEEKELEKIL
                     VSLEKQIDFMKSYYRAKYTLSNWGILQTIPMLAIYYFFSDKMDLEEAYHFASEELKQQ
                     IETQILGDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSYRELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEILSLSAVVLNKEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     KRAWQPKSMIFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDA
                     GRYSYREIYERYLLKSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGVHY
                     IEGAYWSAEPDLPYLHKRKILMLVEDVWLLVDDIRCQGQHEALTQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNDLERSNKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSEDICVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            26709..27710
                     /locus_tag="VQ664_000768"
     CDS             26709..27710
                     /locus_tag="VQ664_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET2788960.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(27820..28155)
                     /locus_tag="VQ664_000769"
     CDS             complement(27820..28155)
                     /locus_tag="VQ664_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2788961.1"
                     /translation="MKSLARLLNIHVFISIFLFFALISGAVSHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLTNPVQWKFSIFLVVTIISSLAYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(28166..28408)
                     /locus_tag="VQ664_000770"
     CDS             complement(28166..28408)
                     /locus_tag="VQ664_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2788962.1"
                     /translation="MKKEKKQLRYPGLKAGSIYGTVIFFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            complement(28419..28961)
                     /locus_tag="VQ664_000771"
     CDS             complement(28419..28961)
                     /locus_tag="VQ664_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3278 domain-containing protein"
                     /protein_id="HET2788963.1"
                     /translation="MKKETFTEKLIKRTYGISGPLDEYKRREADSIGNQVFIVLFYLM
                     IFGNLIPLLLAYKYPQEVALIYPPLILVIALIAAGYVTYQMKKTGITVIEPDMLNEKE
                     SKQLHYPGLKAGLFFGLWMFFITPLLSILIDEGQDYFHSLLTIRNGVSSILGSIFFGA
                     SIQFLISRRIAKTKKNQDED"
     gene            complement(28977..29171)
                     /locus_tag="VQ664_000772"
     CDS             complement(28977..29171)
                     /locus_tag="VQ664_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2788964.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWEEDF"
     gene            29337..30287
                     /gene="rsmH"
                     /locus_tag="VQ664_000773"
     CDS             29337..30287
                     /gene="rsmH"
                     /locus_tag="VQ664_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HET2788965.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNHYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLKPKMELVSRKPILPSAEELEANNRSHSAKLRVARKIHK"
     gene            30299..30616
                     /gene="ftsL"
                     /locus_tag="VQ664_000774"
     CDS             30299..30616
                     /gene="ftsL"
                     /locus_tag="VQ664_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HET2788966.1"
                     /translation="MAEKMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            30620..32872
                     /gene="pbpX"
                     /locus_tag="VQ664_000775"
     CDS             30620..32872
                     /gene="pbpX"
                     /locus_tag="VQ664_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2X"
                     /protein_id="HET2788967.1"
                     /translation="MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY
                     ANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQ
                     MDSFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYE
                     PGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGF
                     AHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSF
                     GQGISVTQTQMIRAFTAIANDGVMLEPKFISAVYDPNDQTARKSQKEIVGNPVSKDAA
                     SLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGLT
                     DYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTA
                     KALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAP
                     NQQVLILSDKVEEVPDMYGWTKETAETLAKWLNIELEFQGSGSTVQKQDVRANTAIKD
                     IKKITLTLGD"
     gene            32874..33854
                     /locus_tag="VQ664_000776"
     CDS             32874..33854
                     /locus_tag="VQ664_000776"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HET2788968.1"
                     /translation="MFISISAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLITSVLVAFFFALFSSQFSNNMGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGVIFYLFYERGGDMLSVFGYQVHLGIFYIVFALFWLVGF
                     SNAVNLTDGVDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLSFFIFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
     gene            34463..36568
                     /locus_tag="VQ664_000777"
     CDS             34463..36568
                     /locus_tag="VQ664_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HET2788969.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEF
                     AHYRATGQLPGNAETDVQMPQQASGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELERKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGASDIERLKDMAHRLQEKVIGQDKAVEVVARAIRRNRAGFDEGNRPIGSFLF
                     VGSTGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVVIATS
                     NAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     AKHLEADMEDGVLVIREKA"
     gene            37291..38310
                     /locus_tag="VQ664_000778"
     CDS             37291..38310
                     /locus_tag="VQ664_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic biosynthesis protein"
                     /protein_id="HET2788970.1"
                     /translation="MSNTLKQLLLFREEFIKNILNGIDVDETVVIENDFVEELENFLK
                     ENDLLDFSNSIFFQLSGDKVIVNNIYPGYLAYFNRFLTFYPKIFAIKEVGEYIDFLNF
                     EKRIADMFYCWGFNANSRVLTAEKIIEIPNHQINAKYIKKVIKMSELLFGVDSNNRIR
                     LLNNRRELIKTIFQGSVIKSAIPALAATLDTISNSGSFQISLSKQIINNLVLSGKDKV
                     TIPRIELDNVVLSRQKIIVSVSYINDFLDLRFPDKIEYILNFLEGSGFNTKVMVYFGK
                     IVEEDKNYFVNLEKPQYFDFTSILFNKLFFKELNKFDYMVIEKLIPNLDEDVMMTEYI
                     KEYTE"
     gene            38323..>38638
                     /locus_tag="VQ664_000779"
     CDS             38323..>38638
                     /locus_tag="VQ664_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000603792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2788971.1"
                     /translation="MILSKVRCYIYNSKIRGKVLYELYEFINENKQLMDAINSIKVDS
                     SNGFSIQILHLGEQQTTVLLTDFFTKTLDLFKEFRVTNKSTLEQVKNQISILNSSGPK
                     MDL"
BASE COUNT        12301 a         6337 c         8239 g        11761 t
ORIGIN      
        1 agttactttg agaagttacc gaaaaatatt tttcatatct attgactttt aggggtgaaa
       61 tttggtatga tagtaggcgg tattgtttac cccatttgaa aggccccgga accttccaaa
      121 tacttttcga tgggaaggaa cacccatcac cgtaaacaaa aatcgaacta tatataggag
      181 aaatcatgaa caaaacaaca tttatggcta aaccaggcca agttgaacgt aaatggtacg
      241 tagttgacgc aactgatgta ccacttggac gtctttctgc agtagttgct agcgtacttc
      301 gcggaaaaaa caaaccaaca tttacaccac acactgatac aggtgacttc gtgattgtta
      361 tcaatgctga aaaagttaaa ttgactggta aaaaagcaac tgataaaatc tactacactc
      421 actcaaacca cccaggtgga ttgaaacaaa tctctgcagg tgaacttcgt tctaaaaatg
      481 cagtacgttt gattgagaaa tcagttaaag gtatgcttcc acacaataca cttggacgcg
      541 ctcaaggtat gaagttgaaa gtatttgttg gagctgagca cactcatgct gcacaacaac
      601 cagaagttct tgacatttca ggacttatct aaggaaagga acaaataaag tatgtcacaa
      661 gcacaatatg caggtactgg acgtcgtaaa aacgctgttg cacgcgttcg ccttgttcca
      721 ggaactggta aaatcactgt taacaaaaaa gatgttgaag agtacatccc acatgctgac
      781 cttcgtcttg tcatcaacca accattcgca gttacttcaa ctgtaggttc atacgacgtt
      841 ttcgttaacg ttgtaggtgg tggatacgct ggtcaatcag gagctatccg tcacggtatc
      901 gctcgtgccc ttcttcaagt agacccagac ttccgcgatt cattgaaacg cgcaggactt
      961 cttacacgtg actcacgtaa agttgaacgt aagaaaccag gtcttaagaa agctcgtaaa
     1021 gcatcacaat ttagtaaacg ttaattcgaa agaattacta tacttataca gagcaccttt
     1081 cggggtgttc tttttttata ctttcttact aaattggtgc aattgacaca gttgttgcga
     1141 ctttagttgc ttacaaatgt ggctgcaacc tgacaaggtc agttgcctca aaacgctaat
     1201 caatacaatt atatcaatgt ttcaaagcac tcaaaggttt gccctatggg tgcttttttc
     1261 gtgttttttt gaaaagttta ccttattttt atagtaaggt gaaataagaa taggacaaac
     1321 cgaggatagt caaatcgaat tctaacaatg ttttagaagt agaggtgtac tattctagtt
     1381 tcaatctact atattatgga taatgcaaga ttccatagaa tgggtaagtt agaactcttg
     1441 tgtgaagagt ttgggtataa acttttacct cttcctccct actcacctga gtacaatcct
     1501 attgagaaaa catgggctca tatcaaaaag cacctcaaaa aggtattacc aagttgcaat
     1561 accttttatg aggctctttt gtcttgttct tgtttcaatt gactataaat cgctataaga
     1621 aaaaatcatt ttattggtat aaagaagtga ttgaaagtaa tggcgaaacg ttagataatt
     1681 agttcataaa aaacaagttt agatcctcat ctaaacttgt ttttttaaaa ttgaaggatg
     1741 attttggagg atatgagatg acattgacta ttcatgtata ttataaaggc gatggagatt
     1801 gtgcaataaa gtttgcaaga gaaatgcttg aatctgggct tgtcgcagaa attagatgtc
     1861 aaaaaggtaa tttgaaatac gaatattttt taccaattga aaaagaggga attattctcc
     1921 ttattgatca gtggataaat caagaagctt tagatgaaca tcatcaatca aatacaatgc
     1981 agaaaatctt agatttaaga aaaaaatatc acttgcagat gcaagttgaa cgttatatag
     2041 aagatgattc tgggatgcca gaaagcgata agtcgtttat agacacaggg aattagaatt
     2101 attgtgagag tttttgtagt ttgaaagtat tgaaaatcgt aaagatatca ttacgagaat
     2161 acaagaagat attgttctat ttccattaaa aattacttct ttccttaata ataaggaaaa
     2221 agaatacgtt ttcatctttt ggtttgaggt ttataataag aatatcaaag tcaggaggaa
     2281 aaaagatgac tacttttaaa gatggatttt tatggggtgg tgctgttgct gctcatcaac
     2341 ttgaaggcgg atggcaagaa ggtggcaaag gaattagtgt tgctgatgtt atgactgctg
     2401 gtcgccatgg agtagctcgt gaaattactt tgggagtttt agagggtaaa tattatccaa
     2461 atcatgaggc gatagatttt tatcatcgtt ataaagaaga catagcactt tttgctgaaa
     2521 tgggattcaa gtgcttccgt acctctattg catggacacg tatctttcca aaaggtgatg
     2581 agttagagcc gaatgaagaa ggattacagt tttatgataa tctttttgat gaatgcttaa
     2641 agaatggtat tgaacctgtc atcactctat ctcattttga aatgccttat cacttagtga
     2701 ccgaatatgg tggttggaaa aataggaaat tgattgattt ctttgctcgt tttgcagaag
     2761 tcgtatttaa acgttacaaa gataaggtta aatattggat gactttcaat gaaatcaata
     2821 atcaagcgaa ttatcaggaa gattttgcac catttactaa ctcaggtatt gtatatgagg
     2881 aaggtgataa tagagaagca attatgtatc aagcagcaca ttacgaatta gttgcttctg
     2941 cacgagctgt aaaaattggt catgagatta atccagattt tcaaataggt tgtatgattg
     3001 cgatgtgtcc aatttatcca gttacttgca atcctaagga tatcttaatg gcaatgaaag
     3061 ctatgcagaa gcgttattat tttgctgatg tgcatgtttt aggtaaatat cctgagcata
     3121 ttttcaagta ttgggaacga aaaggtattt cagttgattt tactgaccag gataaagaag
     3181 atttacttgg tgggactgta gattacattg gtttcagtta ctatatgtcc tttgctatag
     3241 actctcatcg tgaaaataat ccttattttg attatcttga aacagaagat ttagtgaaaa
     3301 ataattatgt taaggcttct gaatgggagt ggcaaattga tccagaaggt ttacgttatg
     3361 cgttaaattg gtttacagac cactatcact taccactctt tattgttgaa aatggttttg
     3421 gagctataga tcaagttgca gcagatggta tggtacatga tgattataga attgaatatc
     3481 taggtgccca tattcgtgaa atgaaaaagg ctgtagttga agatggtgtt gatttaatgg
     3541 gttatactcc atggggatgt attgatttgg tttcagctgg taccggtgaa atgcggaaac
     3601 gttatggctt tatttatgta gataaagatg acaatgggaa gggaagttat aatcgttccc
     3661 cgaaaaaatc ttttggctgg tataagaaag ttattttatc taacggtgaa tcagtagaat
     3721 agtataaaca aactgagatt attctcagtt tgtttagcat attgaggaga catatgattg
     3781 gaagtattgc agcaatttta acaacatttg catttttacc acaagttttt cgtgtagtta
     3841 agacaaagga cacaggatct attgctctag gtatgtatgt tatgcaagtt attggtattg
     3901 cattgtggct tgctcatggt attcgtatag gagacttgcc tttgatttta gcaaatagtg
     3961 tttcatttct actctcagga ataattttat tttataaatt gaagtataaa taattttttt
     4021 ccatatcatt taggaaaatg agggaattgt cattgaaaac gctttatttt ataataaaaa
     4081 tagataacaa ataagccaac ttagcacagc tttgattgga tttaagaaaa ggagaaaata
     4141 ttatggcaaa agctttaatt atttgtgcag caggaatgtc ttcatcactt atggcacaga
     4201 aaacaacaga gtttctaaaa ggaaaaggga aagatattgt agttgatgct attagtgcta
     4261 ctgaaggagg gaaagctatc gcagcagcag cttttgattt gtatcttgtc agtcctcaaa
     4321 caaaaatgta ctttaagcaa tttgaagagg ctggttctaa agcaggaaaa ccagttgtac
     4381 aaatacctcc tcaagcctat attcctattc caatgggaat tgaaaaaatg gctaatttga
     4441 ttcttgagaa tatttgatga acacatgaaa tgtcaataaa tatttaagtt aagataaatt
     4501 gttttgagtt tgatataaat tgatttaagt gtataatatg cttcaatata tgaaaacata
     4561 cgttttagga gggaatgaat gtgttaaaca ttaaagagaa agatatcctt caatttttaa
     4621 taaaaaataa ggaacgtttt gttacaagca aagaactggc agaatattta tcctgttcag
     4681 atagaactgt ccgtaatgta ctgaaattaa ttgagaagac aatgattatt caaggagtcc
     4741 ggttgatttc aaaacaaggt caagggtatc aaatattttt tgagaatcaa ggcgcttacc
     4801 aggagtttag acaaacttat gaactggaag aagactatac gaaaactgcg gtttcaaaag
     4861 gtgatgatcg tttagtattt atcttaaata aattattatt tgagcaagtt ccagttcttt
     4921 ttgatgattt agctgatgaa ctttacgtta gtcgttcaac attatctcat gatttcagaa
     4981 agatacgagt gatgttatca gagtataatt tgtccattga gagtagggcg aataaaggag
     5041 tttatgtctc aggcgaggaa cgtgataaac gacgttttat cataaattat ttcctagaga
     5101 atcaattttt taaaacaata cattgctatg taaaatttaa cttttttgct caaactgttc
     5161 cattagaaga atttgctaga attgttttgg atgaatgcca agaggccaac ctaaaactat
     5221 ctgattttgt actacagaat ttagtagttc acatagcatt gtctgtgatt cgtttaaaat
     5281 ccggatttga aataaaaaat atagactgtc agatgactga tgatgcaata gagagaaagg
     5341 ttgctcaaag aattctttct aaagtaagag aagtaacaaa tcaggaattt ccagttcagg
     5401 aaatagacta cattactttg catttgttag ctaagagtca acaatgtcaa aaaaatcaga
     5461 agaatatttc tgaagaagtt ttaaaaaaat ctttatttaa aacatttcag aatttaggat
     5521 tagatgatat gtataacttt tcttcagatt tccaactaat tgaaggattg ataactcatc
     5581 taatgacact acaagtacgt ttagaaagcc ggattacctt aaataaccct ttggtagatg
     5641 aaattaaaca gaattatagt gatatattct ttatgactag agaaattctt gcaaatatgg
     5701 acaagttctt ggagtggaca atatcagatg atgaagtagc atatgtaagt cttcactttt
     5761 tagctgctat ggaacgtagc aaagagagta ctaagtttaa tattcttgct atttgtgcaa
     5821 caggatttgg tgcagcccaa atgttaagaa atcgtttgga aacggagttt gggaagcgag
     5881 tagaagttgt tgatgtaata ggctattatg aattgaatca agaaaaactt aaaggaatag
     5941 attttatagt gtcagctgtt gatttatcaa atctatattt tcaaattcca gtttttaaag
     6001 ttagtgtgtt tcttaagagt gatgagatgg aaatgattag aaaagctatg gatcagatgc
     6061 aagtttctag ttatgtacaa tcatcaaaga ttaataaatt tgaaaacaac agctttagac
     6121 agtattttag taaagaaaat tttttaatat gtactgaatc agacaaggta aatttacttg
     6181 aaaagatggt tgagagttta tctgttggtg aatcaaatga gtttgaacaa tctttacttt
     6241 atggaattaa acagcgcgaa gaattaagtt cagttgtttt ttctgaaaaa attgcagttc
     6301 cgcatcctat tcagcccttt ggtacagagg gaaaggtttc ggttgcaatc tgtaaagatt
     6361 cgttactctg ggataatcaa agttcatatg tccagctagt atttcttcta tctccatcaa
     6421 tatatgggaa cgaaggtttg gcaactgtga ctaaaaagat agtctctctg acagagaatg
     6481 atgagttgca aaatcagcta atatcttgca ataactttga agattttatt agcatatttg
     6541 agaagataaa ataggaggtt catatgaatc aagaggaact gcaggttgca gcatttgaaa
     6601 ttatcctgca ttcgggaaat gcaaggtcag aaatacatga agcatttgca aaaatgagag
     6661 aaggtagttt tgatgatgca gaaagtaaat taaatcaatc aaatgagata attcttgaag
     6721 cgcatcatgc acaaaccaaa ctcttgcaag aatacgcaag tggagtggaa attaaaattg
     6781 aaattatcat ggtacatgct caagatcatt taatgaccac tatgacatta ttagaagtag
     6841 caaaggaaat gttagctctt tataagaaag ttaactaaat atgtgttgtt atataaggag
     6901 gaaatgatat ggataaaaaa gaacgacaaa agattgaaca acaacgtcga gagatggctc
     6961 taactaatac tttttttaat cgatatcttc ttctacgtta ttcaatagca ctcttctttt
     7021 ttgggaatat ttattggctt ttgaatcagt ttattaatcc ctcgcctatt attattttcc
     7081 ccattatgct catagtattt tctattttag caactgttga acaatttaaa ctctatggaa
     7141 ataggaaaga aaagttggga ataacactaa tgtttgttag aatacaaata cttatttcaa
     7201 taggattact tgttttaact tggacaagtt ggtttaagaa tctttttccg atttttgaaa
     7261 ataaccaagt agcacgttta tttgtttttg tagttcttct attaggttta gttctgagtt
     7321 tgttagacat tagaagaatt aaaaaaattt ataaacgaac agataaggct tatcaacaat
     7381 ttgtccaatt ggaaaagaac tcacttagtt tataatcctg atctagtata atttgtattt
     7441 gaaactagtc tttagaaagt aaaaattatt atgttttatt aaggaggtct atttatggat
     7501 caacaaaacg ggttgtttgg ttttcttgaa aaccatgtta tgggaccaat gggcaaactt
     7561 gctcagttta aagtagtgcg tgctatcacg gctgcaggta tggctgctgt accatttact
     7621 attgtaggat caatgttttt ggtattcagt attttgccac aagctttctc attttggcca
     7681 attgtggcag atattttctc tgcttcattt gataaattca catcacttta catggttgca
     7741 aactatgcga ctatgggttc tctatctctt tatttcgttc tatcacttgc atatgaattg
     7801 acaaaaattt atgcagagga agaagaactc aatatgaatc ctcttaatgg tgccttgctc
     7861 gccttgatgg cttttgtcat gacagtaccg caaatcattt ttgatggtgg aatgatgaag
     7921 actgtgacaa gtctaaaaga aggtgcagta attgcagatg gatgggcaat gggaaatgga
     7981 gtcgcacgtt ttgggacaac agggattttt accgcaatca ttatggcaat tgtgactgtt
     8041 cttatttatc gtatgtgtgt taaacataat tgggttatta aaatgcctga agctgttcca
     8101 gaaggagttt ctcgtggatt taccgctttg gttccgggat ttgttgttgc atttgttgtt
     8161 atctttatca acggtcttct tgtagcaatg ggaacagata tttttaaagt cattgcaatt
     8221 ccatttggtt ttgtatccaa tctgactaat tcgtggattg gtttaatgat tatttatcta
     8281 ttgactcaac tactttggat tgtaggtatc cacggtgcga acattgtttt tgcatttgtt
     8341 agtccaattg ctcttgctaa catggctgaa aatgctgctg gcgggcactt cgctgttgca
     8401 ggtgaatttt ctaatatgtt tgtaattgca ggtggttctg gtgcaacttt aggactatgt
     8461 ttatatattg cttttgcctc taaatctgaa cagcttaaag caataggacg agcatctgta
     8521 gttccagcct tatttaatat taatgaacca ttaatttttg gattacctat tatctataat
     8581 ccagccttgg ctataccatt tattttagca ccaatggtta ctgctactat ttattacgta
     8641 gcgaattctc taaactttat taagccaatt atcgcacagg ttccatggcc aactccagta
     8701 gggattggag ctttcttagg gacagcagat cttcgagctg tattagttgc tctagtatgt
     8761 gcatttgcag cattcttagt ctatcttcca ttcatccgtg tatatgatca aaaattggtg
     8821 aaagaagagc aaggtatcta ataagtaaaa aagtatactc gatgatagaa tccatatagt
     8881 ttaaataatg agtgttaata ttagcagtga agaggtcttt ttaagatatt cttctctgct
     8941 ttttcatatt ttttcgctat gtagggtatg aagcaaaata gaaagtagtt cgaatagttg
     9001 ataaacagga aactgctgtt atttaaaaaa aacaataaag taaagtatgt tatcgtagaa
     9061 tacgatacaa tagtaaaaaa gcaaaaagaa tgcgttttat atttgggttt gaggtttata
     9121 aaataggata agcgtgctga aaacttagat atgacaaaca aaataaaatt tttaaaagct
     9181 acatagaaac atggtataat gtatctaaag gaggtagcat atgtccttag atatagataa
     9241 agaaaagatg acaatcatgg gaatagcttt tgaaaacaga tccgttttta agagtgtttg
     9301 gtatgcttta agtacaaata tgattgaagg atggcgacct acggttagtg atgttgaaaa
     9361 attacgagat gaagctcttg ctctggggat gacttaatga agcgcaactg ttatgagtct
     9421 tatgactatg ttgatccgga taatttatat accgatccgg gttcttcagt tctaagaaat
     9481 aagcaggaag gaaaaaagca cgcgagcttg aatatcgtat gattgctagt aagagtttga
     9541 aattatttat caatcctatc ttagttaata gtttaaaagt agtttgtttc acaactgcat
     9601 aagcttagaa aagttgaaaa gtgataactc tttaataaac tcttggtttg ttaaaagata
     9661 ttttgtccac tacatttttt caattgacta ttatttgtca tagatataac agatagaaca
     9721 gatagaacat tgcattcaga ataatgaaaa acgcatcaaa aatggtgcgt tctgttttta
     9781 tgctaccata aaaggaggaa aacaaattga aaatttttaa gggagagttt tatcgaatct
     9841 ctgtattaac agacaagcta gtaaggttag aatactctca aactggaagt tttgaggata
     9901 gaacgacaca acttatctat aatagagatt ttggccaagt ttcgttagat tatatcgaga
     9961 catcaaacgt actagatatt atgacggact attttcatct gcactttaat aaaggagaat
    10021 ttaacgccga aaatttattt atagaattaa aaggaaattt tgccgtatat ggtagtcgct
    10081 ggtattttgg tgaatctatt gaaacgttaa aaggaacagc tcggactctg gataaggcag
    10141 atggagcaat ctcgttagaa gatggaatta ttagccgaaa tggtatagcc ttattggatg
    10201 attctcaagg atttatttgg gatgaacaat ctggttatat tgagagagaa aatcaaattg
    10261 acctgtattt ctttgcctat gggcatgatt atagaggagc aatcagagac ttttaccatt
    10321 tgactggttc aacacccttg ttgccaagat atgctttagg caattggtgg agtagatatt
    10381 ggccttatac gtcggatgaa tacttggatt taatagacag atttgaaaca gagaaaattc
    10441 cattatctat cggtgtgtta gatatggatt ggcatataac tgacattcca gctcgttttg
    10501 gaagtggctg gacaggatat agttggaata gaaacttaat accaaatcca gaacagttat
    10561 tgcaacaact tcatgataga aagttaaaac tctccttaaa tgtccatcct gctgatggga
    10621 tacgggctta tgaagaagct tatcctcaaa tcgcaaaacg gttggggtta aatgtagaac
    10681 tagaagaacc tgctattttt gattttttta atccctcttt tagggaagcc tactttaaag
    10741 atgttcatta tgagctagaa aagcagggag tagatttttg gtggattgac tggcaacaag
    10801 ggacacaagg tatgctagat ccactttggc ttttaaacca ttatcactat caggatagtt
    10861 gtaaaaatgc agaaggtggt ttgattttat caagatatgc aggtcctggt agtcaccgct
    10921 accctgttgg tttttcaggg gatactatta ttagttggaa ttccttaagg tttcaaccct
    10981 attttacagc gacagcatct aatatcggtt atagttggtg gagtcatgat atcggtggac
    11041 atatgttggg ggattatgac gaagagctac aaactagatg gctacagttt ggtgttttta
    11101 gtccgattac tcgattacat agttctagaa gtccttttaa tagtaaagaa ccttggttct
    11161 tttcagaaac aacatctaag attatgaaga aataccttcg tttgagacat cagatgattc
    11221 cctatctata taccatgaat gtaaagacac atgaggaagg tgccccatta atcagtccaa
    11281 tctattattt ctatccagag aatgatgaga gctataatgt tccaaaccaa tacttttttg
    11341 gaacagaact gatggtggct cccattgtag aaaagatgga tttgacattc caatctgcaa
    11401 aagtagatgt atggttccct gaaggtgaat ggtatgactt cttttcagag aaaaaataca
    11461 caggtggtgt gaagttaagt gtttataggg acatctcgac tacgcctgtg tttgcaaaaa
    11521 gtggtgcaat cattcccttg gttggttctg agataggtat gggtgttgat ttacctgagg
    11581 ttgtagattg gtatgtattc ccagggaaac aacatttttt tgaaatgctt gaagatcaaa
    11641 atggtcaaag atataaaaca agattatcaa tcgattggga aatgggaatg gtagagttag
    11701 cattacaagg agattctagt atcgttccaa gcaatagaaa acatagaatt cattttaaag
    11761 gaacgaatgt gtctataatt gaattgccaa ataagaatga tacagctaaa tttgaatgga
    11821 aagataataa aaggacatct ttaaatgacg aagtttttag actactaaag acagcttctc
    11881 ttccatatga attaaaagat agattgttaa atcaattcat caatgcgaaa aactctcatg
    11941 acttaatgaa tatcttgcat catcaggata aggaattgag agggcgtttg ttggaaatga
    12001 tatttactag ccaaaactaa ttgaaataat tagaaagtca tttgtttagt gtatatgaag
    12061 attctgtatg gtattcgtta tcactggtca cattgaaaat gtgaaataag cacctacaac
    12121 atagacttta caacacttca tgtttcatat catggggtgt ttttctattt aagtcaaagc
    12181 ccatcaaaaa atctcactat tcatcaggtt aaaggaaacc taatcatagt gagattgtga
    12241 attatagtag agtttgtatc gcctcttcaa tttgttttgg gtctgttttt gaagaaaagc
    12301 gttcaaagac ttgcccatct cgaccgatga gaaacttagc gaaattccat tcgattcgtt
    12361 ttcctagtgg gccggatttc tggtctttta accagacata gagagggtct gcttccttac
    12421 cgttgacctt aatcttggca aaacgtggga aggtggtttg aaaatgtagg ctacagaagg
    12481 cgttgatttc ctctgcgctg ccgggtgctt gtcccataaa ctgattgcaa gggaaatcca
    12541 atatttcgaa gccctgatct tgatagcgtt catagagttc ttgaagtccc tggtactggg
    12601 gcgttaaacc acatccagta gcagtgttga caatcaagag aactttgcca cgatagctat
    12661 ccaagggagt tgcttggttg ttttggttca aaacggaaaa atcataaagt gaagtcatga
    12721 gggcctcttt tctttttcta cattgtaaca gtttttactt ttttcgtcga gtcggatgga
    12781 agatattgtt gaagaataag ccttcaatat gatagaaacc gtttacaaat aactttaaaa
    12841 atggtatgat ttaattaaac cggtttactt agttgctata aatctctaat ttgagattta
    12901 gttcctattg attttacaat atgtttattg gagtgtatac atgcaaacaa aaacaaagaa
    12961 gctcattgtg agtttgtctt cacttgtttt atcaggattt ttattaaacc attatatgac
    13021 agttggagcg gaagaaacga ctacgaatac cattcagcaa agccagaagg aagttcagta
    13081 tcagcaaagg gatacaaaaa atttagttga aaatggtgat tttggtcaga cggaggacgg
    13141 aagcagtccg tggacaggaa gcaaagctca ggggtggtca gcttgggtag accagaagaa
    13201 tagtgcagat gcctcaactc gagtcattga ggctaaggat ggggctatca ctatctcaag
    13261 ccatgagaaa ttaagggcag cggttcaccg tatggttcct attgaagcta agaaaaagta
    13321 taaactgcgt ttcaagatta aaacagatca taaagtcggg attgccaaag ttcgtatcat
    13381 tgaggaaagt gataaggaca agcgattgtg gaattctgca acgacgtcag gaacaaagga
    13441 ctggcagacc attgaagcag actatagccc gactttagat gttgataaaa tcaagctgga
    13501 gttattctat gaaacaggaa ctgggactgt ttcctttaag gatattgagc tggtagaggt
    13561 agcagaccag ccttctgagg actatcaaac agataaacag cttgaggaaa agattgattt
    13621 accaattgga aaaaaacatg ttttttctct tgcggactat acttataagg tagaaaatcc
    13681 tgacgttgct tcagtcaaaa atggaatttt agaacctctt aaggaaggga caaccaatgt
    13741 cattgtcagt aaagatggca aggaagtgaa aaagattcct ttgaagattc tagcctctgt
    13801 taaggatgca tacacagacc gtttggatga ctggaatggc atcatcgctg ggaatcaata
    13861 ctatgattct aaaaatgaac agatggccaa attaaaccag gaattggaag gaaaggtagc
    13921 tgatagccta tctagtattt caagtcaggc ggaccgcacc tatttgtggg aaaaattttc
    13981 aaattataaa atgtctgcaa atctgactgc cacttatcgg aaattggagg agatggccaa
    14041 gcaagtgacc aatccttctt ctcgttatta tcaagatgaa actgtcgttc gaacagtcag
    14101 ggattccatg gaatggatgc ataaacatgt ctacaatagt gaaaagagca ttgttgggaa
    14161 ctggtgggat tatgaaatcg gtacacctcg tgccatcaac aataccttgt ctctgatgaa
    14221 agaatacttc tctgatgagg aaattaaaaa atatacagat gtgattgaaa aatttgtacc
    14281 agatcccgaa catttccgaa agacgactga taacccattt aaggctctag gtggaaactt
    14341 agttgatatg ggaagagtaa aagtaatagc tggtttactg cgtaaggatg atcaagaaat
    14401 ttcttctacc attcgctcga ttgagcaagt gttcaagttg gtagaccaag gtgaaggttt
    14461 ttatcaagat ggatcctata tcgaccatac caatgttgcc tatacgggtg cttatgggaa
    14521 tgttttgatt gatggcctgt ctcaactgtt gccagtcatt caaaagacca agaatccaat
    14581 cgataaagat aaaatgcaaa ccatgtacca ctggattgat aaatcgtttg ctcctttgct
    14641 ggtgaatgga gagctgatgg atatgagtcg tggacgctcg atcagtcgtg caaatagcga
    14701 ggggcacgtg gccgcagtag aagtactaag agggattcac cgaatagcgg atatgtctga
    14761 aggagaaacc aaacaacgtt tgcagagtct tgtgaagacc attgttcaat cggatagtta
    14821 ttatgatgtc tttaagaatt tgaagactta taaggatatc agtttgatgc aatccttgtt
    14881 aagtgatgca ggagtcgcaa gtgttccaag aacaagttac ctatctgcct ttaacaagat
    14941 ggataaaaca gccatgtaca atgcagagaa agggtttgga tttggcttgt cactcttttc
    15001 cagtcgtacc ttgaattacg aacacatgaa caaggaaaat aaacgtggtt ggtatacgag
    15061 tgatgggatg ttctatcttt acaatggcga tttgagtcac tatagcgatg gctactggcc
    15121 aacagttaat ccatataaga tgcctggtac aacagagacg gatgctaaga gagcggatag
    15181 cgatacaggt aaagttttac cgtctgcttt cgttggaacg agcaaactag atgatgccaa
    15241 tgcgacagca accatggatt tcaccaactg gaatcaaaca ttgactgctc ataagagctg
    15301 gtttatgcta aaggataaga tcgccttttt aggaagcaat atccaaaaca cttcaacaga
    15361 tactgctgca actacaattg accagagaaa actggaatca agtaatccat ataaagtcta
    15421 tgtcaatgat aaagaagcct cccttacaga acaagaaaag gattatcctg aaacccaaag
    15481 tgtcttttta gaatcatccg attcgaaaaa gaatattggt tactttttct ttaagaagag
    15541 ttcaatcagt atgagtaagg ctttgcaaaa gggagcctgg aaggatatca atgaaggaca
    15601 gtcagacaag gaagttgaaa atgaatttct tacgattagt caggctcata agcaaaatgg
    15661 agattcttat ggctatatgc tcatccctaa cgtgggtcgt gccaccttca atcaaatgat
    15721 aaaagagtta gaaagaagcc tcatcgaaaa taacgaaacc cttcagtctg tttatgatgc
    15781 caaacaagga gtttggggca ttgtgaaata tgatgattct gtctctacta tttccaacca
    15841 attccaagtt ttgaaacgtg gagtctatac cattcgaaaa gaaggggatg aatataagat
    15901 tgcctactat aatcctgaaa cccaggaatc agctccagat caggaagtct ttaaaaagct
    15961 agagcaagca gctcagccac aagtacagaa ttcaaaagaa aaggaaaaat ctgaagagga
    16021 aaagaaccat tcggatcaaa agaatctccc tcagacagga gaaggtcagt caatcttggc
    16081 aagtctaggg ttcttgctac ttggggcgtt ttatttattc cgtagaggaa agaacaacta
    16141 atttgttcat catctagatg aattacatga aactgtggaa aatagaaaaa atccgaagaa
    16201 ggccaaatat cttcggattt ttcttttaaa aaaggataag ttgatactta tcctttttac
    16261 ttcattatgt gactatagcg ttttgaaact agaataggac atcataactg ctaaaagatt
    16321 tctataaatt catttgattt tcctaatcaa tttattcgta tcctatttca ctctactata
    16381 ttagtccgtc tcgcacctca cggagcgaga caaaacaacc acccgctatg cgggtgcgcg
    16441 tcgaaggtta taccaaaaaa actccaaacg cgatacaata aaggtgttca atccacttgt
    16501 aaagcgaaag gagaaaaaat atggcacaaa aggctcatag tttatctcac acaaagtgga
    16561 ggtgttctat cacattgtgt tcacccctaa gtatagacga aaagtcatct ataatcaata
    16621 tagaagtagt ttaggcgaaa tatttcatcg cttgtgtagt tataaaggtg ttgaaatgat
    16681 cgagggtcac ttaatgccag accatgtaca catgttagtc agtattccac taaggctaag
    16741 tgtttcgagt ttcatgggtt atttaaaagg aaaaagtgca ctcatgatgt ttgacaaaca
    16801 cgccaatctc aagtacaagt ttgggaatcg gcatttctgg gtggaaggtt attatgtaag
    16861 tccagtaggg cttaatgaag ccacaattaa gaaatatagt caagattaaa gaaattatcc
    16921 agtggatgat ttcttcacga gtatgaaaat ttgagaacta gtaaagtatg atatatagta
    16981 aaatgaaata agaacaggac aaaatcgatc aggacagtca aatcgatttt taacaatgtt
    17041 ttagaagtag aggtatacta ttccagtttc aatctactat agcactagat aaattgagtg
    17101 taaaagaata tgaggatccc tttagggata gtggtaagta ataccaaagt ctcttaaaga
    17161 ggcaagtgac gagtcaagag caataaggct tgaacaacgt aaaagccagc gtctttaggc
    17221 gctggctgat gatttgggct tatagctctg ggataaacca cccgttagac gggtagttat
    17281 gattttatct gagtgtaata tactgttggg caatctcgct gatgcggtca aagttgcctt
    17341 gggaagcgag tttattgagt tcgccaccaa ttccaacggc atctgcacca gcagcgaacc
    17401 attgagggat gttgtttagg ccgactcctc cggttaccat tacggaaact tgtgggatcg
    17461 gtgccttgac tgcagagata tatgctggac tgagagtact acctgggaag agtttgatga
    17521 tttcactacc ggcttcaagt gcagtcgtga tctctgtgag ggtaatacag cctggaatgt
    17581 acggtgtgct gtagagattg cacattttcg cagtttcagc atggaaagat ggagaaacaa
    17641 cgtaatttgc tccagctaga atggcatctc tagcagttac ggcatcaagc acagtacctg
    17701 caccgataca aacactctga tcgtcctgat acaagtctac aagttccttg atgatttgtc
    17761 ctgcatactg attggtatag gcgatttcaa tagctttgat accgcccttg atacaagcaa
    17821 tcgaggcttg tagtccttct tcctttgtat ttcctcgaat gacagcgaca attttctgtt
    17881 tttttagttc aataatcgta tctgatttgg tcatgtaatt ctcctaacga atgatatctt
    17941 gtgcatttgc cagtaaattt tcaatactag ttgcggaagt ggagagatgg tctcctggaa
    18001 gagtgcattt gagagttgcg ctcgcaactg caaagtcaat ggtagttttt agggaggaat
    18061 gatggagtag ttggtaaagg gcaccagata taaaggcatc cccgctacca attcgttgat
    18121 agactgcagt ttttagttgg acagactctt caaatcgttc ttccagagca taggcttgat
    18181 agacattttt gtcttgctca tcactagatc ggagggtatg gaaaatggcc ttgaaaccat
    18241 aggcttcttt taaaagtcgc atgcgatttt ccacctcttc taggctagca ctgtctcttg
    18301 gaaacatctc tagattttgg tcatcaatca tgagaggatc aataccgaag caatagtcag
    18361 taaaacgtgc aaacttagaa aattcatact tggcttctag gactgaaatc atctttgttc
    18421 tcagattgag atccattgaa acgacaattc ctcggcgctt ggcttcttcc aagagtagga
    18481 gaaggatcgc acggacctct tgaccgatag ctatggtgat tccactaaaa tgaaaatggc
    18541 taatcccctg aaagagagaa tccatatcta gcatgtttgg ccgaatctgg ctgatactcg
    18601 tatgcttacg atcgtagaaa acttcacttt gacgacaacc aaagccgttc tccaaatagt
    18661 agaggccgat tcgatcgcca agccgacaga ttgaactggt atcgatttgg tgctgtttca
    18721 agaatgtgag aaaacgatct ccaatctcgt tggcagggag tgcggtaaag actttcgttg
    18781 agatacccag ggcttgcaaa ttacaagcga tgttaatttc tgatccgcca aaataagtcg
    18841 aactggcaac atgatcgccg atactggtgg catctaatgg tgagattcga attaatggtt
    18901 cgccaaacag taatattttc gtcatccatt agttcctttc tggtttagaa tagctttact
    18961 tggctaatac ttctttcaaa taagcagcga cttcatcatc ttggcagttt tcaaagaagt
    19021 attcttggaa gtatttgcca gagatggtgt ctttgaggaa gtcttggtcg attgttttaa
    19081 ggatggtcat caaatcattg tgggtgattt gtttcacctc gtttaagata cgagcgttgc
    19141 gttgttcagg gattacacgt tctcttgggt agccaccgcc catttcttca gcaaataagc
    19201 gttcaaacat caatttgagg gtcagttctg ccccccagcc aaatcctttg gcataaggga
    19261 tagacaaggc gttaccacca ttgatttgag aataaaggta agcgtcagtt gggtccactg
    19321 ctagaccaca gacaacacca gggaagctgt ttaaagcaag catagcccct acacccgtac
    19381 cacagccggt aacaacaaag tcaactgcct ttgtatttaa aaggatggca gccattagtc
    19441 cgttctgcac ataagttaat tgactttctc cttcttctcc acgcatacca tagttaaata
    19501 attggtagtc ttttttatct gtcgcttctt ttagactatc gtaaataatg tgattcttgc
    19561 tagcttgact attttcattg attaatgcga ttttcataag atcttctttc tatttttact
    19621 caggttgttt tccgatgtag gctaagatac cgccatctac atataggatg tggccattga
    19681 caaaattgct ggcatcacta gcgagaaaga cagcagggcc catcaaatct tcaggatttc
    19741 cccaacgtgc agcaggtgtt tttgcaatga tgaactggtc aaatgggtgg cgagaaccat
    19801 cttcttgcaa ctcacgaaga ggtgctgttt gaggagtggc aatataaccc ggtccaattc
    19861 cgttacattg gatattggct ccaccgtatt cagacgcaat gttgcgggtc aacattttca
    19921 agcccccttt agcagcagca taagcgctaa ctgtttcacg tcccagttcg ctcatcatcg
    19981 aacaaatatt gataatcttt ccatgccctt tctttatcat agaaggaata actgcctttg
    20041 aaacgataaa tggtgcgttt aagtcaatat cgatgacctt acggaaatca gcggcgctca
    20101 tttcgcacat tggaactcgg cggataatac cagcgttatt aacgaggatg tcaatgacac
    20161 caacctcttg ttcgatttgc ttgaccatgg cttggatacc gtcctcgtct gtcacgtcac
    20221 agacatatcc atgggcttcg atgccaactt cacgataagc ttcaatccct ttattgacca
    20281 gatcttgatt gatatcgtta aagacaatag tagcgccggc ttcagcgtag gatttggcaa
    20341 tagcaaatcc aattccataa gaagcgccgg tgatgagagc aatttttcct tttaaagaaa
    20401 actgctcaat tgagaatgat gtatttgtca tttgatactt cctttcaaat ttgttaagac
    20461 ttctctataa ccaaattata ttctagcaaa ccggttttgt caataaataa atatttttat
    20521 ttataaaaag atttgttttc ctgaaaaacg gaatgttttg aaatttctgt ttattaaaat
    20581 ggttaaaaag ataatgaaag cgctaatatt tttttaaaaa aactattgac aagataaaaa
    20641 taaaggatta caatggggaa tataaagtaa accggtaaac ctaaacaaga aaggagaaaa
    20701 gatgaaaatt gtacttgtag ggcatggaca ttttgctaca gggatttata gttctttaca
    20761 attgattgca ggtaatcaag aaaatgtgga ggcgattgac tttgtggaag gaatgtcagc
    20821 agatgaactc aagcaaaaaa tcttacttgc aatttcaaat gaagaagaag ttttaatcct
    20881 aagtgatctc ttgggaggat cgccattcaa ggtttcttct accataatgg gagaaaatcc
    20941 agtcaaaaca atgaatgttc tctcgggttt gaacttagcc atgttaatgg aagcagtctt
    21001 tgctagaatg gctcatagct ttgatgaggt tgttaataaa tcagtagtgg cggcccaggg
    21061 cggagtcgta aatggtaaag aattgttttc aacggatgca gaggaagaag atttcgaatc
    21121 gggtatttaa agggtaaaag aatgataaaa aaggttacga ttgaaaaaat aaaatcgcct
    21181 gagcgcttct tagaagtacc acttctgacg aaagaagaag tcggccaggc aatcgataag
    21241 gttattcggc agttagaact caaccttgac tatttcaagg aagatttccc gacgccagct
    21301 acctttgata atgtctatcc aatcatggat aacacggaat ggaccaatgg tttctggaca
    21361 ggagaactgt ggttggctta tgaatacagt caacaggatg catttaaaaa catcgctcat
    21421 aaaaatgttc tttctttcct ggatcgtgtc aataagagag tagaattgga tcaccatgat
    21481 ctcggcttct tgtacacacc gtcttgtatg gctgaatata agataaatgg agatggagag
    21541 gctagagaag caaccttgaa agctgcagat aagttgattg aacgctatca agaaaaaggt
    21601 ggttttattc aagcttgggg agacttgggc aagaaagagc attaccgttt gattatcgac
    21661 tgcttgctca atatccaact cttattcttt gcttatcaag aaacaggcga tcaaaaatac
    21721 tacgatattg cagaaagtca tttctatgct tcagctaata atgtaatccg tgatgacgct
    21781 tcgtccttcc acaccttcta ttttgatcct gagacaggtc aaccctttaa aggtgtaacg
    21841 agacaagggt atagtgatga ttcatgctgg gcacgtggtc aatcatgggg agtctatggt
    21901 attcctttga cttatcgtca cttaaaagac gagtcctgct ttgacttgtt taagggtgtg
    21961 accaattatt tcttgaatcg tctgccaaaa gatcatgtgt cctattggga tttgattttt
    22021 aatgatggta gtgctcaatc acgagattct tcagcaacag ctatcgccgt ctgtgggatt
    22081 catgaaatgc taaaacatct cccagaggtg gatgctgaca aagatattta taaacatgct
    22141 atgcatgcca tgcttcgttc cttgatcgaa cattatgcaa atgatcaatt tacccctggt
    22201 gggacaagtc ttctccacgg tgtgtactca tggcattcag gtaaaggagt ggatgaaggc
    22261 aatatctggg gtgactacta ttacctagaa gcccttatcc gtttctacaa agactggaac
    22321 ctatattggt aggaggagaa atatgacaat gccaaatatt attatgaccc gtatcgatga
    22381 acggttgatt catggacaag gacaactttg ggtaaaatac ctagcttgta atacggtcat
    22441 tgttgccaat gacgaagtaa gcacggacaa gatgcaacaa actctgatga aaacagttgt
    22501 gccagactca gttgccatgc gtttcttccc tttgcaaaag gtgattgata tcattcacaa
    22561 ggctaatcct gctcaaacga tctttatcgt tgtaaaggat gtaaaggacg ctttaacctt
    22621 ggtagaaggt ggtgtcccta tcaaagaaat caatattggg aacattcaca atgcccctgg
    22681 taaagagcaa gtgacacgct ccatcttcct gggtgaagag gacaaggcag ccctcaagga
    22741 attaagccaa actcatcaag taacatttaa tacgaaaaca actccaacag gaaatgatgg
    22801 agctgttcaa gtcaacatta tggactatat ttaaaagagg agatcgttat gtcgattaat
    22861 gtatttcaag cgattttaat tggattatgg acagctttct gttttagtgg aatgctgtta
    22921 ggaatttaca ccaatagatg tattgttctg tcatttggtg tcggaattat tctaggtgat
    22981 ctgcctactg ctcttgcaat gggagctatt ggtgaattgg cttatatggg attcggtgtt
    23041 ggtgctggag gtactgttcc accaaaccca atcggacctg gtatctttgg taccttgatg
    23101 gctatcacta gtgctggtaa agtcagtcca gaagcggctc ttgccctctc tactccgatt
    23161 gctgtggcga ttcaattctt acaaactttc gcctacactg tacgtgctgg tgcgcctgaa
    23221 acggcgatga agcacttgaa aaaccataat ttgaagaaat tcaagtttac tctaaatgca
    23281 acaatttggt tgtttgcctt tattggattt accttgggtt gcttgggtgc cctttcaatg
    23341 gataccttgt tgaaactcgt agactacatt ccaccggtat tacttacagg tttgacagtt
    23401 gctggtaaaa tgctcccagc tatcggtttt gcgatgatct tgtcagtgat ggctaagaaa
    23461 gagttgattc cctttgtctt gttgggatat gtttgtgcag cttatctaaa catcccaaca
    23521 attggtattg caattgtagg tactatcttt gctttgattg aattttataa caagccaaaa
    23581 acagcgaatc atgtggtaga ggaggaagca cacgatgact ggatctaaca aattaacaaa
    23641 acgtgattat cttaaaacgt ctttgcgggc attcttttgt caaaatggat ttaactatag
    23701 taactatcaa gggttgggat atgccaatgt gatgtatcct gctttgaaaa aacactatgg
    23761 agaggatcag gaaggtttct accaagcctt ggaagaaaac tgtgaattct ataataccaa
    23821 cccacacttc ctgcctttta ttaccagctt gcatcttgta atgttggaaa atggccgtcc
    23881 ggcaaaagaa acacgtagca tcaagatggc cttgatggga ccattggcag gtattgggga
    23941 ttctctttct caattctgtt tagctccatt gttctcaacc atcgcagctt cgtttgctca
    24001 agaaggcttg gttgtcggtc caatcttgtt cttccttgcg atgaatacga ttttaacagc
    24061 gattaaattg tcaactggtc tgtatggata caaactagga acaactgtga ttgataaact
    24121 aagcgaacag atggcaacga tttctcgtat tgccaatatt atcggtgtaa ccgtaattgc
    24181 tggtttggca gcgacatctg ttaagattat ggtgccgatt acctttgctg caggggaagt
    24241 taaagcagac gctaaacaaa gtatcgtaag tattcaggga atgcttgata aggttgctcc
    24301 agctcttcta ccagccctat ttacactttt agtttactac ttgatcaaag aaaagaaatg
    24361 gacaacatat aaactcgtta ttttaacagt tgtcatcgga attatcggaa gctggcttaa
    24421 gattatagct taatggatac aacattgttt tatggaatag tgattgtctt ggcagtgagt
    24481 ccccttttac tgtcaagctt tcattctatt cgtcagcaaa agttgcttcg caaacagacg
    24541 gagcaacgac aagagtattt agcttcttta acatctggtg atgaagtgtt gttattgtct
    24601 ggaattcatg gaaaaatcat ttctatcaaa gatgacttgg tctccttgca gattgcaaaa
    24661 ggtgtggtca tctatgtaga aaaggaaagt gtaatgggaa agacaaaaga actgcttttt
    24721 aagtagttct ttttctggta atagataatg aaagaagaaa gaagacaatt ttttgaaaga
    24781 gtcgatggaa accaatgtcg tgattatatc ttgtcgcact gttcaaaaga ctatgagaaa
    24841 gtcaagagtt cccttgaacg cttgatggac aatcgtttta tgtttgatag tccttgggat
    24901 atggagcctt gttcaaaaat ccatcaaatc cagccgatgg tatgggatca agtatttgaa
    24961 gatgatccag aatgggctta tatgctcaat cgacaagaat atctcttgca gtttatgata
    25021 gggtatgtgg tagaaggaga taaggactat attcaaaagt gcaagttctt tctatttgat
    25081 tggattgagc aggtgagaga attttctcct caatccttga tgactagaac cttggatacg
    25141 ggtattcgtt cctttacttg gttgaaacta ctcttgctcc tcttgaaatt tgacatgcta
    25201 gaggagaaag aactagagaa aattttggtc agtctagaaa agcagattga ctttatgaaa
    25261 agctactatc gcgccaagta cacccttagt aactggggga ttttacaaac aattccgatg
    25321 cttgctatct attatttctt ttcagataag atggacctag aagaagctta ccattttgct
    25381 tcagaggagt tgaaacagca aattgagaca cagattttag gagatggaag ccagtttgaa
    25441 cagtcgattc tctatcatgt agaggtttat aaagccttgc tggatttgtg tctcttgctt
    25501 ccagacttgc aagatagtta ccgagagttg ctggaaaaga tggcgaccta tattcaaatg
    25561 atgacaggct tagatggacg aactttggct tttggtgata gcgattctac agaaacgaca
    25621 gaaattttga gcctgtctgc tgtggttttg aacaaggaag accttcttaa cggtctggat
    25681 gttaaagtcg atttgcttag cctcttgttc ctggggcgag aaaaggtcaa gcgactgcag
    25741 gaatttgaaa agagagcttg gcagcctaag tccatgatct ttgaagactc tggacatgtc
    25801 tgcattaagg atgaacatcg ttatctattt ttcaaaaatg gtccgctagg aagtgcccat
    25861 agccatagtg acgagaatag tttttgctta cagtatcaag gacaacctat tttcatagat
    25921 gctgggcgtt attcttatcg ggagatatat gaacgttatc tcttaaagag tgcttggagt
    25981 cattcgacct gcattgtaga tgggaaagct ccggaaagaa tcacgggatc ctgggaatat
    26041 gaatactatc ctcactccct gttttgtcac cataaagaaa gggagggagt gcattatatt
    26101 gaaggggctt attggtcagc agaacctgat ttgccttatc ttcacaagag aaaaatcctc
    26161 atgttggtag aggatgtctg gctcttggtg gatgacatca ggtgtcaagg tcagcatgag
    26221 gcgttgactc agtttatcct tgacaaggat gtgacctatc aagatgggaa aatcaatcag
    26281 ttgagactat ggagtgaagt tgattttgat ttggaagata ccatcatttc tcctaaatac
    26341 aatgatcttg aaagaagtaa caaactcacc aagcgccaat tctttgagaa tcagatgctg
    26401 gattatacca tcattgcgca tgagagtttt gaaatcatcc gtcattctgt ctaccagaca
    26461 gatgatcgtg aagtggaaaa tgctctggct tttgaagtga aaaatgacga aacagacaag
    26521 ctgattctgt tattaagcga ggatatttgt gtaggtgaaa aattgtgcct cgttgacgga
    26581 acaaaaatgc gtggaaaatg tctagtatat gataaaataa atgagagaat gattcgcttg
    26641 cagtgctaga aataggcatt ttgaatagtg aatatgttat aataagtatt agtaggaggt
    26701 gttttagatt ggagaagaaa ctgaccataa aagacattgc ggaaatggct cagacctcga
    26761 aaacaaccgt gtcattttac ctaaacggga aatatgaaaa aatgtcccaa gagacacgtg
    26821 aaaagattga aaaagttatt catgaaacaa attacaaacc gagcattgtt gcgcgtagct
    26881 taaactccaa acgaacaaaa ttaatcggtg ttttgatcgg tgatattacc aacagtttct
    26941 caaaccaaat tgttaaggga attgaggata tcgccagcca gaatggctac caggtaatga
    27001 taggaaatag taattacagc caagagagtg aggaccggta tattgaaagc atgcttctct
    27061 tgggagtaga cggctttatt attcagccga cctctaattt ccgaaaatat tctcgtatca
    27121 tcgatgagaa aaagaagaaa atggtctttt ttgatagtca gctctatgaa caccggacta
    27181 gctgggttaa aaccaataac tatgatgccg tttatgacat gacccagtcc tgtatcgaaa
    27241 aaggttatga gcattttctc ttgattacag cggatacgag tcgtttgagt actcggattg
    27301 agcgggcaag tggttttgtg gatgctttaa cagatgctaa tatgcgtcac gccagtctaa
    27361 ccattgaaga taagcatacg aatttggaac aaattaagga atttttacaa aaagaaatcg
    27421 atcccgatga aaaaactctg gtatttatcc ctaactgttg ggccctacct ctagtcttta
    27481 ccgttatcaa agagttgaat tataacttgc cacaagttgg gttgattggt tttgacaata
    27541 cggagtggac ttgcttttct tctccaagtg tttcgacgct ggttcagccc tcctttgagg
    27601 aaggacaaca ggctacaaag attttgattg atcagattga aggccgtaat caagaagaaa
    27661 ggcaacaagt cttggattgt agtgtgaatt ggaaagagtc gactttctaa aatgaaggaa
    27721 aatgacttgc aatctctgtt aagaaataaa ataatcccac ctagaacaag ctaggtggga
    27781 ttatttgctt atgaaatgag aaattatggg agcaagctcc taaatcaact gtttttgatc
    27841 tacttcttta actacttgat aaaagttata gaagtaggcc aaacttgaaa tgatggttac
    27901 gactaggaat attgaaaatt tccattggac agggttggtt aaaagttgtg gaaaggatat
    27961 gaggagaaag aagagggctg cgttgaggac aggtatccgt tttgattgta ttttctcaag
    28021 tcctttattg agcgcaggaa gaaagaggag taggagtagt aaaactgtat gagaaacagc
    28081 tcctgaaata agggcgaaga aaaggaaaat actgataaaa acatgaatgt tcagtagtct
    28141 agctagtgat ttcataaggc acctcctaat cctggtcttt tttagctctt gcaatacgaa
    28201 gtgagtcgac aatatgtatc atcactccga aaaagaaagc tcccagtata gttttaaaaa
    28261 tatgttttgt atttagaaga gaactgataa aatttggatt ttcacttgtt agggtatcaa
    28321 tgagtggaat tataaaaaat atcactgttc cataaatcga acctgctttc agaccaggat
    28381 aacgtaactg tttcttttct tttttcatga gtttcctcct aatcctcatc ttgatttttc
    28441 ttagtttttg caatgcgacg ggagatgagg aactgtatgc tcgctccgaa gaaaatagaa
    28501 ccgagaatac ttgatacacc atttcttata gtgagaagag aatgaaaata gtcctgacct
    28561 tcatctatga gtatactgag aagaggagtt ataaaaaaca tccatagacc aaagaacaaa
    28621 cctgctttca gacctgggta gtgtagttgc ttgctttctt tctcattcag catatctggt
    28681 tcaatgactg tgatgcctgt ttttttcatt tggtaggtga catagccagc agcgatgagg
    28741 gcaatcacta aaatcagagg aggatagatt agagccactt cttgagggta tttataggct
    28801 agaaggagtg gaataagatt tccgaaaatc atcagataaa agaggacgat aaagacttgg
    28861 ttcccaatac tatcggcctc acgccgtttg tattcgtcaa ggggaccaga aataccgtat
    28921 gtgcgtttga tcagtttttc agtgaaggtt tcttttttca tgagtttgct ccttttttaa
    28981 aaatcttcct cccaaaagag actgttgagg tcagtttgga ggctgcgggc gagattgaga
    29041 cagagttcca aggttggatt gtacttgtcg ttttcaatca tattgatagt ctgtctcgag
    29101 acaccgatat ccttggcgag ttcgagctgg gaaataccca attccttgcg aaattctttc
    29161 acacgattca tctggtctcc tttctgattt atgtcgtata tatttgacta tattatagtc
    29221 ttttaaacat aaagtgtcaa gtatatttga catatttttt gaagaaatag tagtctcctt
    29281 gtcctatttg tctgacaagt gcaagctggt cggatttgtg gtaaaataga taagatatga
    29341 caaaagaatt tcatcatgta acggtcttac tccacgaaac gattgatatg cttgacgtaa
    29401 aacctgacgg tatctacgtt gatgcgactt tgggtggagc aggccatagc gagtatttat
    29461 taagtaaatt aagtgaaaaa ggccatctct atgcctttga ccaggatcag aatgccattg
    29521 acaatgcgca aaaacgcttg gcaccttaca ttgagaaggg aatggtgacc tttatcaagg
    29581 ataacttccg tcatttacag gcacgtttgc gcgaagctgg tgttcaggaa attgatggaa
    29641 tttgttatga cttgggagtg tctagtcctc aattggacca gcgtgagcgt ggtttttctt
    29701 ataaaaagga tgcgccactg gacatgcgga tgaatcagga tgctagtctg acagcctatg
    29761 aagtggttaa tcactatgac tatcatgatt tggttcgtat tttcttcaaa tacggtgagg
    29821 ataaattctc taaacagatt gcgcgtaaga ttgagcaagc gcgtgaagtg aagccgattg
    29881 agacaacgac tgagttagca gagattatca agttggtcaa acctgccaag gaactcaaga
    29941 agaagggtca tcctgctaag cagattttcc aggctattcg aattgaagtc aatgatgaac
    30001 tgggagcggc agatgagtcc atccagcagg ctatggatat gttggctctg gatggtagaa
    30061 tttcagtgat tacctttcat tccttagaag accgcttgac caagcaattg ttcaaggaag
    30121 cttcaacagt tgaagttcca aaaggcttgc ctttcatccc agatgatctc aagcccaaga
    30181 tggaattggt gtcccgtaag ccaatcttgc caagtgcgga agagttagaa gccaataacc
    30241 gctcgcactc agccaagttg cgcgtggcca gaaaaattca caagtaagag ggaaaaagat
    30301 ggcagaaaaa atggaaaaaa caggtcaaat actacagatg caacttaaac ggttttcgcg
    30361 tgtggaaaaa gctttttact tttccattgc tgtaaccact cttattgtag ccattagtat
    30421 tatttttatg cagaccaagc tcttgcaagt gcagaatgat ttgacaaaaa tcaatgcgca
    30481 gatagaggaa aagaagaccg aattggacga tgccaagcaa gaggtcaatg aactattacg
    30541 tgcagaacgt ttgaaagaaa ttgccaattc acacgatttg caattaaaca atgaaaatat
    30601 tagaatagcg gagtaagata tgaagtggac aaaaagagta atccgttatg cgaccaaaaa
    30661 tcggaaatcg ccggctgaaa acagacgcag agttggaaaa agtctgagtt tattatctgt
    30721 ctttgttttt gccatttttt tagtcaattt tgcggtcatt attgggacag gcactcgctt
    30781 tggaacagat ttagcgaagg aagctaagaa ggttcatcaa accacccgta cagttcctgc
    30841 caaacgtggg actatttatg accgaaatgg agtcccgatt gctgaggatg caacctccta
    30901 taatgtctat gcggtcattg atgagaacta taagtcagca acgggtaaga ttctttacgt
    30961 agaaaaaaca caatttaaca aggttgcaga ggtctttcat aagtatctgg acatggaaga
    31021 atcctatgta agagagcaac tctcgcaacc taatctcaag caagtttcct ttggagcaaa
    31081 gggaaatggg attacctatg ccaatatgat gtctatcaaa aaagaattgg aagctgcaga
    31141 ggtcaagggg attgatttta caaccagtcc caatcgtagt tacccaaacg gacaatttgc
    31201 ttctagtttt atcggcctag ctcagctcca tgaaaatgaa gatggaagca agagcttgct
    31261 gggaacctct ggaatggaga gttccttgaa cagtattctt gcagggacag acggcattat
    31321 tacctatgaa aaggatcgtc tgggtaatat tgtacccgga acagaacaag tttcccaacg
    31381 aacgatggac ggtaaggatg tttatacaac catttccagc cccctccagt cctttatgga
    31441 aacccagatg gattcttttc aagagaaggt aaaaggaaag tacatgacag cgactttggt
    31501 cagtgctaaa acaggggaaa ttctggcaac aacgcaacga ccgacctttg atgcagatac
    31561 aaaagaaggc attacagagg actttgtttg gcgtgatatc ctttaccaaa gtaactatga
    31621 gccaggttcc actatgaaag tgatgatgtt ggctgctgct attgataata atacctttcc
    31681 aggaggagaa gtctttaata gtagtgagtt aaaaattgca gatgccacga ttcgagattg
    31741 ggacgttaat gaaggattga ctggtggcag aatgatgact ttttctcaag gttttgcaca
    31801 ctcaagtaac gttgggatga ccctccttga gcaaaagatg ggagatgcta cctggcttga
    31861 ttatcttaat cgttttaagt ttggagttcc gacccgtttc ggtttgacgg atgagtatgc
    31921 tggtcagctt cctgcggata atattgtcaa cattgcgcaa agctcatttg gacaagggat
    31981 ttcagtgacc cagacgcaaa tgattcgtgc ctttacagct attgctaatg acggtgtcat
    32041 gctggagcct aaatttatta gtgccgttta tgatccaaat gatcaaactg ctcggaaatc
    32101 tcaaaaagaa attgtgggaa atcctgtttc taaagatgca gctagtctaa ctcggactaa
    32161 catggttttg gtagggacgg atccggttta tggaaccatg tataaccaca gcacaggcaa
    32221 gccaactgta actgttcctg ggcaaaatgt agccctcaag tctggtacgg ctcagattgc
    32281 tgacgagaaa aatggtggtt atctagtcgg gttaaccgac tatattttct cggctgtatc
    32341 gatgagtccg gctgaaaatc ctgattttat cttgtatgtg acggtccaac aacctgaaca
    32401 ttattcaggt attcagttgg gagaatttgc caatcctatc ttggagcggg cttcagctat
    32461 gaaagactct ctcaatcttc aaacaacagc taaagctttg gagcaagtaa gtcaacaaag
    32521 tccttatcct atgcctagtg tcaaggatat ttcacctggt gatttagcag aagaattgcg
    32581 tcgcaatctt gtacaaccca tcgttgtggg aacaggaacg aagattaaaa acagttctgc
    32641 tgaagaaggg aagaatcttg ccccgaatca gcaagtcctt atcttatctg ataaagtaga
    32701 ggaagttcca gatatgtatg gttggacaaa ggagactgct gagacccttg ctaagtggct
    32761 caatatagaa cttgaatttc aaggttcggg ctctactgtg cagaagcaag atgttcgtgc
    32821 taacacagct atcaaggaca ttaaaaaaat tacattaact ttaggagact aatatgttta
    32881 tttccatcag tgctggaatt gtgacatttt tactaacttt agtaggaatt ccggccttta
    32941 tccaatttta tagaaaggcg caaattacag gccagcagat gcatgaggat gtcaaacagc
    33001 atcaggcaaa agctgggact cctacaatgg gaggtttggt tttcttgatt acttctgttt
    33061 tggttgcttt ctttttcgcc ctatttagta gccaattcag caataatatg ggaatgattt
    33121 tgttcatctt ggtcttgtat ggcttggtcg gatttttaga tgactttctc aaggtctttc
    33181 gtaaaatcaa tgaggggctt aatcctaagc aaaaattagc tcttcagctt ctaggtggag
    33241 ttatcttcta tcttttctat gagcgcggtg gcgatatgct ttctgtcttt ggttatcaag
    33301 tgcatctagg gattttctat attgtcttcg ctcttttctg gctagtcggt ttttcaaacg
    33361 cagtaaactt gacagacggt gttgacggtt tagctagtat ttccgttgtg attagtttgt
    33421 ctgcctatgg agttattgcc tatgtgcaag gtcagatgga tattcttcta gtgattcttg
    33481 ccatgattgg tggtttgctc agttttttca tctttaacca taagcctgct aaggtcttta
    33541 tgggtgatgt gggaagtttg gccctaggtg ggatgctggc agctatctct atggctctcc
    33601 accaagaatg gactctcttg attatcggaa ttgtatatgt ttttgaaaca acttctgtta
    33661 tgatgcaagt cagttatttc aaactgacag gtggtaaacg tattttccgt atgacgcctg
    33721 tacatcacca ttttgagctt gggggattgt ctggtaaagg aaatccttgg agcgagtgga
    33781 aggttgactt cttcttttgg ggagttgggc ttctagcaag tctcctgacc cttgcaattt
    33841 tgtatttgat gtaagaatgg caccctgatg tttcagggtg tttttgtgtt taaatacaca
    33901 atgaaaatca aagaacaaac tagaaagcta actttaggct gctcaaaata tagtagattg
    33961 aaactagaat agtacacctc tacttctaaa acatttttag aaatcgattt gactgtcctg
    34021 aacgatttat cctgttctta tttcatttta ctatacagtt ttgagatggt tgatagaact
    34081 gacgaagtca gctcaaaaca ctgttttgag gttgtagaca aggcgaagct gatgtggttt
    34141 gaagaggttt tcgaagagtg taaaaaaata ttggtcagtt aaagtcaaaa ctcttgacct
    34201 tttctgacca atgtagtata ttatgaacgt aaggtaaatg aaagccttac tagaacactt
    34261 atttaaagta aaatagaaag aggtgagtct atgtttcatc tagcaatctt cagaggtaaa
    34321 gatagtctac tcctgcttga aaaagaaaaa ccagaaatag tacgtagggt agcgatctag
    34381 ctagtctaaa ttttttaaaa caatggtcaa agatagtcaa tatcagtaat cataactaag
    34441 taaacaaaaa gaggtaaaga atatgaataa caactttaat aattttaata acatggatga
    34501 tttatttaac caattgatgg gtggtatgcg aggatatagt tctgaaaatc gccgttactt
    34561 aattaatgga cgcgaagtca cacctgagga atttgctcac tatcgtgcga ctggtcaatt
    34621 accaggaaat gcagaaactg atgtgcaaat gccacaacag gcatcaggta tgaaacaaga
    34681 cggtgtcctt gcaaaactag gtcgaaactt aacagcagaa gcgcgtgagg gcaagttgga
    34741 tcctgttatc ggacgaaaca aggaaattca agaaacatct gaaatcctct cacgccgcac
    34801 caagaacaat cctgttttgg tcggagatgc aggtgttggt aagacagcag ttgtcgaagg
    34861 tctagcgcaa gccattgtga acggagatgt tcctgctgct atcaagaaca aggaaattat
    34921 ttccattgat atctcaggtc ttgaggctgg tactcaatac cgtggtagct ttgaagaaaa
    34981 tgtccaaaac ttagtcaatg aagtgaaaga agcagggaat attatcctct tctttgatga
    35041 aattcaccaa attcttggtg ctggtagcac tggtggagac agtggttcta aaggacttgc
    35101 ggatattctc aagccagctc tctctcgtgg agaattgaca gtgattgggg caacaactca
    35161 agacgaatac cgtaacacca tcttgaagaa tgctgctctt gctcgtcgtt tcaacgaagt
    35221 gaaggtcaat gctccttcag cagagaatac ttttaaaatt cttcaaggca ttcgtgacct
    35281 ctatcaacaa caccacaatg tcatcttgcc agacgaagtc ttgaaagcag cggtggatta
    35341 ttctgttcaa tacattcctc aacgtagctt gccagataag gctattgacc ttgtcgatgt
    35401 aacggctgct cacttggcgg ctcaacatcc agtaacagat gtgcatgctg ttgaacgaga
    35461 aatcgaaacg gaaaaagaca agcaagaaaa agcagttgaa gcagaagatt ttgaagcagc
    35521 tctaaactat aaaacacgca ttgcagaatt ggaaaggaaa atcgaaaacc acacagaaga
    35581 tatgaaagtg actgcaagtg tcaacgatgt ggctgaatct gtggaacgaa tgacaggtat
    35641 cccagtatcg caaatgggag cttcagatat cgaacgtttg aaagatatgg ctcatcgctt
    35701 gcaagaaaag gtgattggtc aagataaggc cgtagaagtt gtagctcgtg ctatccgtcg
    35761 taaccgtgct ggttttgatg aaggaaatcg cccaatcggc agcttcctct ttgtagggtc
    35821 tactggggtt ggtaagacgg agcttgctaa gcaattggca ctcgatatgt ttggaaccca
    35881 ggatgcgatt atccgtttgg atatgtctga atacagtgac cgcacagctg tttctaagct
    35941 aattggtaca acagcaggct atgtgggtta tgatgacaat agcaatacct taacagaacg
    36001 tgttcgtcgc aatccatact ctatcattct cttggatgaa attgaaaagg ctgatcctca
    36061 agttattacc cttctcctcc aagttctaga tgatggtcgt ttgacagatg gtcaaggaaa
    36121 tacagtaaac ttcaagaata ctgtcgttat tgcgacctca aatgctggat ttggctatga
    36181 agccaacttg acagaagatg cggataaacc agaattgatg gaccgtttga aacccttctt
    36241 ccgtccagaa ttcctcaacc gctttaatgc agtcatcgag ttctcacact tgactaagga
    36301 agacctttct aagattgtag atttgatgtt ggctgaagtt aaccaaacct tggctaagaa
    36361 agacattgac ttggtagtta gtcaagcggc taaagattat atcacagaag aaggttacga
    36421 cgaagtcatg ggggttcgtc ctctccgtcg cgtggttgaa caagaaattc gtgataaggt
    36481 gacagacttc cacttggatc atttagatgc taaacatctg gaagcagata tggaagatgg
    36541 cgttttggtt attcgtgaga aagcctaaga tagaattttg aggataaaaa agaaggagcc
    36601 agctgaaaaa aactggttcc tttttaggta cgacaggcat gtcgtatagt agaagtgtat
    36661 tattccagtt tcaatatact atagtagctc agaagtcggt acttaaacgt gctatatcaa
    36721 aaccagtcct tgaaaaacgt ggactggttt cgtgtttgga ttattacctt gaacgacatg
    36781 cgttaaaagt tagttgaacc gccgtatgcc gaacggtacg tacggtggtg tgagaggggc
    36841 tagagattat cccctactcg attgtctata gctatagggg taaagttatt agagaggttg
    36901 ctagtttata gagacatctt gatttgtaaa aagttaaatt ttagacaatt atccccttta
    36961 aaaaatctat taaaccatag ctagttgaag taaattttta tagaacataa ttttatttat
    37021 caagacattg tagagttgag gcaaattgaa aaagaaagtt taaaagttga taataagtca
    37081 ataagaaagc tattaattct aacgagatta tttgatagta atttgttttt tcagctacta
    37141 ttcggacaat gttattataa taaacacagg agagaacacc agaaggtagg gacatcagaa
    37201 gaaatagttc aggatatagt taacataatc atcaaagaag ctcctagact cgctaatgtt
    37261 aatttggaaa catattatcc agatgaatat atgtcaaata cattgaagca attactactt
    37321 tttagagagg agttcataaa aaatattttg aatgggattg atgtggatga aacagtagta
    37381 atagaaaatg attttgtaga agagttggag aactttttaa aagagaatga tttgctagat
    37441 ttttcaaata gcatattttt tcagttatct ggagataaag taatagtgaa taatatttat
    37501 ccaggatatt tagcatattt taataggttc cttacatttt atccgaaaat attcgctatt
    37561 aaagaagttg gagaatatat tgacttttta aattttgaaa agagaattgc ggatatgttt
    37621 tattgttggg gatttaatgc aaattctaga gtgttgacag ctgaaaaaat aattgaaatc
    37681 ccaaatcacc aaatcaatgc taagtacata aaaaaagtta taaaaatgag tgaactcttg
    37741 tttggtgttg atagtaataa cagaattcgg ttgcttaaca atagaaggga attgataaaa
    37801 actattttcc aaggttctgt aattaagtca gcaattcctg ctctagctgc tactttggat
    37861 acaatcagta acagtggatc atttcaaatt tctttatcaa agcagataat taataattta
    37921 gtattaagtg gtaaagataa agttacaatt cctaggatag agttagataa tgttgttctt
    37981 tcaagacaga agattattgt atcagtttcg tatataaatg attttttgga tttgagattt
    38041 ccagataaaa tagaatacat tttaaatttt ttagaaggat ctggtttcaa tactaaagta
    38101 atggtctact ttgggaaaat tgtagaagaa gataagaact attttgttaa tcttgaaaaa
    38161 cctcagtatt ttgattttac cagtatactt ttcaataagt tattctttaa agaattaaac
    38221 aagtttgatt acatggttat tgaaaaactc attccaaatc ttgatgaaga tgtaatgatg
    38281 acagagtata taaaagagta tactgaatag gagcaatcta ttatgatttt aagtaaagta
    38341 cgttgttaca tatataattc taaaattaga ggtaaagttc tgtatgaatt atatgaattt
    38401 ataaatgaaa ataagcaatt gatggacgca attaattcaa ttaaagttga cagtagtaat
    38461 ggttttagta ttcaaatatt acatttagga gaacagcaaa caactgtctt attaacagat
    38521 ttttttacta aaactttaga cttgtttaag gaatttaggg ttacaaataa gagtactctt
    38581 gagcaggtga aaaatcaaat tagcatacta aattcttctg gtccaaaaat ggatttaa
//
LOCUS       DAVBIC010000016        38071 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.016, whole genome shotgun sequence.
ACCESSION   DAVBIC010000016 DAVBIC010000000
VERSION     DAVBIC010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 38071)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38071)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38071
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.016"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            complement(320..517)
                     /locus_tag="VQ664_000780"
     CDS             complement(320..517)
                     /locus_tag="VQ664_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2788972.1"
                     /translation="MLATLESEARKKVGYLQVKTVAEGSNKDYDRTNDFYRGLGFKKL
                     EIFPQLWNPQNPCQILIKKLE"
     gene            complement(502..780)
                     /locus_tag="VQ664_000781"
     CDS             complement(502..780)
                     /locus_tag="VQ664_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HET2788973.1"
                     /translation="MFVIEEVKDENQKKAVVAEVLKDLPEWFGIPESTQAYIEGTTTL
                     QVWTAYQESDLTRFVSLSYSSEDCAEIDCLGVKKLIKVEKLGANCLLL"
     gene            complement(819..1604)
                     /locus_tag="VQ664_000782"
     CDS             complement(819..1604)
                     /locus_tag="VQ664_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2788974.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLAQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLVFFVISLKLWDKGLDSYESAGS"
     gene            complement(1606..2424)
                     /locus_tag="VQ664_000783"
     CDS             complement(1606..2424)
                     /locus_tag="VQ664_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HET2788975.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVIYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            complement(2426..3418)
                     /locus_tag="VQ664_000784"
     CDS             complement(2426..3418)
                     /locus_tag="VQ664_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2788976.1"
                     /translation="MAMIEVEHLQKNFVKTVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQDNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPDSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQEIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYDGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
     gene            complement(4463..4681)
                     /locus_tag="VQ664_000785"
     CDS             complement(4463..4681)
                     /locus_tag="VQ664_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001859328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HET2788977.1"
                     /translation="MKKISVTVIGYFEINIDENITDILYVNGTAILYHYLRSIVSIVS
                     AIDSSEAMLLPTINVLELLDKSQPFEEE"
     gene            4839..4916
                     /locus_tag="VQ664_000786"
                     /pseudo
     CDS             4839..4916
                     /locus_tag="VQ664_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(5577..6266)
                     /gene="rplA"
                     /locus_tag="VQ664_000787"
     CDS             complement(5577..6266)
                     /gene="rplA"
                     /locus_tag="VQ664_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HET2788978.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMGLVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKAKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
     gene            complement(6473..6898)
                     /gene="rplK"
                     /locus_tag="VQ664_000788"
     CDS             complement(6473..6898)
                     /gene="rplK"
                     /locus_tag="VQ664_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HET2788979.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAVRMIEGTARSMGFTVID"
     gene            complement(7021..7737)
                     /locus_tag="VQ664_000789"
     CDS             complement(7021..7737)
                     /locus_tag="VQ664_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HET2788980.1"
                     /translation="MKKRYLVLTALLALSLAACSQEKAKNEDGAAKTEQTAKADGTVG
                     SKSQGAAQKKAEVVNKGDYYSIQGKYDEIIVANKHYPLSKDYNPGENPTAKAELVKLI
                     KAMQEAGFPISDHYSGFRSYETQTKLYQDYVNQDGKEAADRYSARPGYSEHQTGLAFD
                     VIGTNGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AASGLSLEEYFGFEGGDYVD"
     gene            complement(7740..8210)
                     /locus_tag="VQ664_000790"
     CDS             complement(7740..8210)
                     /locus_tag="VQ664_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HET2788981.1"
                     /translation="MCLICQRIELIKKGENPYFVKELETGYLVIGDHQYFAGYSLFLA
                     KEHVSELHHLEKKTRIRFLEEMSVVQEAVAKAFAAEKMNIELLGNGDAHLHWHLFPRR
                     RGDMNGYGLNGRGPVWWIPFEEMTAEICQSKPDEIKRLVERLSSEVDKLLEIKE"
     gene            complement(8212..9249)
                     /locus_tag="VQ664_000791"
     CDS             complement(8212..9249)
                     /locus_tag="VQ664_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HET2788982.1"
                     /translation="MNQTVEYIKELTAIASPTGFTREISNYLVKTLEGFGYQPVRTAK
                     GGVNVTIKGQNDEQHRYVTAHVDTLGAIVRAVKPDGRLKLDRIGGFPWNMIEGENCTV
                     HVASTGQKVLGTILIHQTSCHVYKDAGTAERTQDNMEVRLDVKVSNEKETRALGIEVG
                     DFISFDPRTVVTDTGFIKSRHLDDKVSAAMLLNLLRIYKKEKIELPVTTHFAFSVFEE
                     VGHGANSNIPAQVVEYLAVDMGAMGDDQQTNEYTVSICVKDASGPYHYDFRQHLVALA
                     KEQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVVATERM
                     VDAYLKSALVD"
     gene            complement(9347..10672)
                     /gene="brnQ"
                     /locus_tag="VQ664_000792"
     CDS             complement(9347..10672)
                     /gene="brnQ"
                     /locus_tag="VQ664_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HET2788983.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAAAYLISLNPSKILDRIGRILTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVVGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(10843..10935)
                     /locus_tag="VQ664_000793"
     CDS             complement(10843..10935)
                     /locus_tag="VQ664_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET2788984.1"
                     /translation="MRSARACQFLLEQGYNVINVQGGMLAFEEL"
     gene            complement(10978..11130)
                     /locus_tag="VQ664_000794"
     CDS             complement(10978..11130)
                     /locus_tag="VQ664_000794"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET2788985.1"
                     /translation="MKEIAFDAFYQLYQNDQLSLVDVREVDEFAALHLEGAHNLPLSQ
                     LADSYD"
     gene            complement(11290..11868)
                     /locus_tag="VQ664_000795"
     CDS             complement(11290..11868)
                     /locus_tag="VQ664_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HET2788986.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFAAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPCT
                     GFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFPLV
                     HPSPRNQIWMAKNPWFEAEVVPDLKKRIKTIL"
     gene            complement(11922..13322)
                     /gene="pepV"
                     /locus_tag="VQ664_000796"
     CDS             complement(11922..13322)
                     /gene="pepV"
                     /locus_tag="VQ664_000796"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HET2788987.1"
                     /translation="MIAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGAARLHSFTGGLREN
                     MVPESATAVVSGDLTDLQAKLDAFVAEHKLRGELQEEAGQYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFGFAGPAKDYLDIAGKILLNDHEGENLKIAHVDEKMGALSMNAGV
                     FRFDETSADNTIALNIRYPKGTSPEQIKSILENLPVASVSLSEHGHTPHYVPMEDPLV
                     QTLLNVYEKQTGLKGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(13335..13940)
                     /locus_tag="VQ664_000797"
     CDS             complement(13335..13940)
                     /locus_tag="VQ664_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HET2788988.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDLKDVRTAIEIATLAPSAHNSQP
                     WKFVVVREKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYNEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDDKLEPSYRLPVDEIIEKR"
     gene            14111..14911
                     /locus_tag="VQ664_000798"
     CDS             14111..14911
                     /locus_tag="VQ664_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2788989.1"
                     /translation="MKKFSLLLAILPFLVACGNQATPKETSAQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTSLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATINFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSADSPSN
                     YIIFSSDQKEFKEQFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            complement(15093..15926)
                     /locus_tag="VQ664_000799"
     CDS             complement(15093..15926)
                     /locus_tag="VQ664_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HET2788990.1"
                     /translation="MNHKIAILSDIHGNATALEAVIADAKTQGASEYWLMGDIFLPGS
                     GANDLVALLKELPITASVRGNWNDCVLEALDGQYGLEDPQEIQLMRMTQFLMERMDPA
                     TTVWLRSLPLLEKKEIAGLRFSISHNLPNKNYGGDLLVENDTEKFDQLLDAETDVAVY
                     GHVHKQLLRYGSQGQQIINPGSIGMPYFNWEALKNHRAQYAVIEVEDGELVNIQFRKV
                     AYDYEAELELAKSKGLPFIEMYEELRRDDNYQGHNLELLASLIEKHGYVEDVKNFFDF
                     L"
     gene            complement(15916..17763)
                     /gene="uvrC"
                     /locus_tag="VQ664_000800"
     CDS             complement(15916..17763)
                     /gene="uvrC"
                     /locus_tag="VQ664_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HET2788991.1"
                     /translation="MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSY
                     FRGIHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKKDEAYFKSMAQEVSDFLKGQDDKIIDDLKSKMAVAAQSMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDTKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGRPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMRHFKSLTKIKEA
                     SVDEIVEVGVPRAVAEAVQRKLNPQETEILLQVAEERVDYQTEGNHNKP"
     gene            complement(17803..18504)
                     /locus_tag="VQ664_000801"
     CDS             complement(17803..18504)
                     /locus_tag="VQ664_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="matrixin family metalloprotease"
                     /protein_id="HET2788992.1"
                     /translation="MRWLFRLIGAFFSFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKMGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWAQASARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLTGQ
                     FLSVTVRLNHYYLSNPYYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANLRKIYETSE"
     gene            complement(18583..19815)
                     /gene="murN"
                     /locus_tag="VQ664_000802"
     CDS             complement(18583..19815)
                     /gene="murN"
                     /locus_tag="VQ664_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HET2788993.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDTFGEQAEFLIASLNFSEYMSKLQGEQSKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(19820..21040)
                     /gene="murM"
                     /locus_tag="VQ664_000803"
     CDS             complement(19820..21040)
                     /gene="murM"
                     /locus_tag="VQ664_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HET2788994.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFAIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRTSKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMVWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(21152..21931)
                     /locus_tag="VQ664_000804"
     CDS             complement(21152..21931)
                     /locus_tag="VQ664_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HET2788995.1"
                     /translation="MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKLALATNRFSHAASFSGALSFQNFSPESQNLG
                     SPAYWRGVFGEIRDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(22000..23661)
                     /locus_tag="VQ664_000805"
     CDS             complement(22000..23661)
                     /locus_tag="VQ664_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HET2788996.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPEHIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKILSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILRESSELINQT
                     VEDYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(23836..26058)
                     /gene="recJ"
                     /locus_tag="VQ664_000806"
     CDS             complement(23836..26058)
                     /gene="recJ"
                     /locus_tag="VQ664_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HET2788997.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQDQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEEGENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIALMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPHRDLFIAFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GEASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNLAASEAVVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKTYYLTGYGTRDQFAKLYKTIYQFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            26335..27093
                     /locus_tag="VQ664_000807"
                     /pseudo
     CDS             26335..27093
                     /locus_tag="VQ664_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
     gene            27133..27897
                     /locus_tag="VQ664_000808"
     CDS             27133..27897
                     /locus_tag="VQ664_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HET2788998.1"
                     /translation="MISLFGLAAAKPVQADTSIADIQKRGELVVGVKQDVPNFGYKDP
                     KTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRGPLLDNEQVDMDIATFTITDERKK
                     LYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQGSITQRLITELGKKKGLKFK
                     FVELGSYPELITSLHAHRIDAFSVDRSILSGYTSKRTELLDDSFKPSDYGIVTKKSNT
                     ELNDYLDNLVTKWSKDGSLQKLYDRYKLKPSSHTAD"
     gene            27910..28587
                     /locus_tag="VQ664_000809"
     CDS             27910..28587
                     /locus_tag="VQ664_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET2788999.1"
                     /translation="MIDLSSWTAYFQDFGQFFNGFLFTLALAIGSFILAMVLGIFFGA
                     MSTSKRPILRILAHIFVEFYQNTPLLVQFVIVFYGLPLISDHTIMIPIYWTAVLCMGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLIILPQTFRIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGAALLYFALCFPVAQFGRKMEQA
                     NKKAYSL"
     gene            28597..29256
                     /locus_tag="VQ664_000810"
     CDS             28597..29256
                     /locus_tag="VQ664_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET2789000.1"
                     /translation="MESILEVLTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNPVLRIISSIYIEFVRNVPNLLWIFTIFLVFKMKSTPAGITAFTLFTSAALAEI
                     IRGGLNTVDKGQYEAGMSQGFTSAQILYYIILPQAIRKMLPAIISQFVTVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLCILIALIYFSFNLAISSLSHMLAKRWQQAA
                     E"
     gene            29551..30741
                     /locus_tag="VQ664_000811"
     CDS             29551..30741
                     /locus_tag="VQ664_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HET2789001.1"
                     /translation="MKSVKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSLTFIL
                     ATRLPLLESWFHGLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNLAIYI
                     FASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFLVGSY
                     ALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLSRPFNYQSGQFAFLK
                     IFQEGFESAPHPFSISGGHGQTLYFTVKNSGDHTNNIYDNLQAGSKVTLDRAYGHMII
                     EEGRENQVWIAGGIGITPFISYIREHPILDKQVHFYYSFRGDENAVYLDLLRNYAQKN
                     PNFELHLIDSTKDGYLNFEQKEVPEHATVYMCGPISMMKALAKQIKKQNPKTELIYEG
                     FKFK"
     gene            complement(31062..31943)
                     /locus_tag="VQ664_000812"
     CDS             complement(31062..31943)
                     /locus_tag="VQ664_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HET2789002.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(32084..33412)
                     /gene="vncS"
                     /locus_tag="VQ664_000813"
     CDS             complement(32084..33412)
                     /gene="vncS"
                     /locus_tag="VQ664_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HET2789003.1"
                     /translation="MKRTGLFAKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGATMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMDLDSQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKDRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTQNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIDFPKVVQD"
     gene            complement(33409..34065)
                     /gene="vncR"
                     /locus_tag="VQ664_000814"
     CDS             complement(33409..34065)
                     /gene="vncR"
                     /locus_tag="VQ664_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HET2789004.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASIAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(34114..34197)
                     /gene="pep27"
                     /locus_tag="VQ664_000815"
     CDS             complement(34114..34197)
                     /gene="pep27"
                     /locus_tag="VQ664_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198524447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HET2789005.1"
                     /translation="MRKEFHNVLSSGQLLADKRPARDYNRK"
     gene            complement(34377..35756)
                     /gene="vex3"
                     /locus_tag="VQ664_000816"
     CDS             complement(34377..35756)
                     /gene="vex3"
                     /locus_tag="VQ664_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HET2789006.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(35808..36455)
                     /gene="vex2"
                     /locus_tag="VQ664_000817"
     CDS             complement(35808..36455)
                     /gene="vex2"
                     /locus_tag="VQ664_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HET2789007.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQIDYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIR
                     LVNKKASKDTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(36468..37745)
                     /locus_tag="VQ664_000818"
     CDS             complement(36468..37745)
                     /locus_tag="VQ664_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2789008.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNGITSYLLQTLLASGDQASLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
BASE COUNT        11028 a         8622 c         6982 g        11439 t
ORIGIN      
        1 aagagtataa gtccaaaact ttcgttaacc gggatacatt ataagcacat tcataccatc
       61 aaaaatagta gcaataaact tgaacaacta ccagaaacac gaaaacaggc ataattgatg
      121 aaatatcagc gctattaaac aatataaata accgctaaga ataaggctta acggttatct
      181 tctacctatc tattttttca actcctcagt cgtttatcta cctataacct aggctttacg
      241 agtgccttgc tctaccaact gagctaaatc ggcgattaca cttacagtat ggcactctga
      301 gaatagatgt caagtaatat tattcaagct ttttaatcaa aatctgacaa ggattttgcg
      361 gattccatag ttgaggaaaa atctctaact ttttaaagcc aagacctcga taaaagtcat
      421 ttgttcgatc ataatcttta ttagaacctt ctgccactgt tttgacctgc agataaccaa
      481 cttttttacg agcttcactc tctaaagtag caagcaattg gctcccaatt tttctacctt
      541 gataagcttt tttacgccga gacaatcaat ctctgcacaa tcttcactcg aataggataa
      601 gcttacaaat ctagtcaaat cactctcctg ataggcggtc caaacttgca gtgtcgtggt
      661 tccttctata taggcttgtg tgctttctgg gattccaaac cattctggca aatccttcaa
      721 aacctcagct acaactgcct ttttttgatt ttcatccttg acttcttcaa ttacaaacat
      781 cataagtttc tttcttgatt ttagtcttac tttagctttt acgaacccgc actttcgtag
      841 gaatctaagc ccttatccca aagtttaagg gaaataacaa agaaaaccag agaaatcaac
      901 atcaaacctc ctacgttaaa gaacacatcc ttttcctgta agaaatagct agctggatag
      961 taggctgtaa aggcgaaagg cacgataaag ctaatcaacc aacgaagaag agaattgtaa
     1021 atagaaatcg gatacttagc aaagtcattg aacatataga agatgtaaat catggcgcct
     1081 gactgcttag tccaaaaggc gatactggct gttgcgattt taagagaagt ataaatcaag
     1141 gtcgcaaaag gaatacaaac taggaaaagc aggaatttcg gaagagtcca aacaatgctg
     1201 gtcactgttg ttcccaataa aataccaccg actaagagtt cacccaaggc atcaatctga
     1261 aaggtttcaa ctaggatgtg aaagagagga ttgatgggac gagtcagata cttgtcaaac
     1321 tccccttttc ggactaggcg ttgccctagt gcccagagat tgtcaaaaaa gagatggtcc
     1381 attcccttgg gaatcaagga aaatccataa atgaaagcta tctcttgaaa ggtccagcct
     1441 tctaggaatg gaatatgttg aaagatgaca ttgagaaaca agagattcaa gccttgagcc
     1501 agaaagactc ccaagacacc aaccacaaaa tccaccttat attccatgat ttgtttgatg
     1561 tattgtctga taaaaatcag atgcattcgt tgatattttt tcatactaac ctccttgaat
     1621 ggtgataaag gactggaccc gtttccaaat caactgagac aatcccacca tcactaagag
     1681 ccagaagaac tgcaaaagga gtgcctgaag aatctgactg gcatcgtatt ttccaacaat
     1741 gatcataact ggagtataaa tcaaggatga aaaaggcaaa aaggagagaa tatctgaaac
     1801 aacctttgga aagaatgcca agggaatcaa actccccgac ataaaagcca ctatggaagt
     1861 cttaagtagg ttggaacccc aaagattttt aaacacaaag gctgaaaatc caaagcaaat
     1921 attaaagaaa aagttaatca gataggcgag cgttaagcta aaaagataaa tgacagttaa
     1981 tcctagcacc tctacaatac cttgacccga tatgattttc atcaagacaa tgacacttaa
     2041 aaatggaagg ccaacgctga taaaaatcaa ccacttggaa ccaagctcgg tgaaaagata
     2101 ggaggccgca aaatgcactg gtcgcaacaa acgcatgata atggagccat ccttgacctc
     2161 ctccccaatc ataaaggacg aatcggatct agtcagaaga ttggtcacaa aactcatgat
     2221 gatgtagagg gtgatatccg ccatactgaa gccctgaatc aaagactctt gcgaagaatc
     2281 aaagacagcc ttccagagat aaaaggccac aaaagccccc atgacatcgc caatccgata
     2341 gagaataaag ttgactcggt aagtaatcaa ctcctgaacc cctgcattga taaagggttt
     2401 ataacgtctc cacaatttga tcatcctaga gctcctttcg gtagaagcga cggataatat
     2461 cctcaatatc cgtatccacc atcttcaaat cgcggatttc aaaatcagac agggtttgct
     2521 tgataatgtc agctgactgg tagcgagaac tatcaaattc aatgttgagg ctgtttcctt
     2581 gtctatcaat ggtcatatca gacagaccgt catagtgaga gacgagatga ctttgacctg
     2641 gtagcagttc aaaagagaga gtcttcatct taccaaaggt ctccttgagt tggctcaccg
     2701 ttccatcaaa aatctcttgc cccttgtcaa tcatgaaaat ccgatcacaa agttgctcaa
     2761 tatcactcaa atcgtgagtg gtcaaaagaa tggtagtttc ttcctcttga ttgatctgag
     2821 taattgcccg acgaatatta tccttaaccg aaacgtccaa accaatggtc ggctcatcta
     2881 aaaaaagaac cttgggattg tggagcaagg aggccgcaat atccgcccgc atccgttgtc
     2941 ccagtgaaag agtccgcacg ggatccttga taaagtcctt caaatccaag acttcattca
     3001 aaaagtccat acgcttatga aagagcgagt ctggcacatc ataaatctct tttaagacag
     3061 tgtaggtctc ttgcagagcc aaatcccacc atagctgggt gcgttgtcca aagactacgc
     3121 caatatcttt gacataatct tgccgattgt cctggggaat cttgccgtta atccgacaaa
     3181 aaccagatgt tggtttcaaa attcctgtca gcattttaat ggttgtcgac ttcccagcac
     3241 catttgcccc gataaatcct aaaatctgcc cttttggaac ctcaaaggtc aaatccttga
     3301 ccgcttcaaa ggtctgcttt tcaggatgaa taaaggagcg caaagccccc ttcaagcccg
     3361 gttccttaac agtcttcaca aaatttttct gaagatgttc cacttctatc attgccatat
     3421 ctatctccct atcgtaagga atagcaacat tgtgttttta actacaaata ttctaaatcc
     3481 ttgctttcta caccttctac attttattac tacaaaaggc tttataccaa cctattatag
     3541 tccaataaaa aacgaaatgc aagagtttgc ctatggattg tgaaattagg atttctctca
     3601 taaaataata cttttaatca aaaattctgt ttaatagttt aaattaccaa cctactcatc
     3661 ttctcaccag agggcggtat taactttgat cataaaatcg gatactccct ctatccagaa
     3721 aatatgctca gaatgattgt ctctaaacaa tacctgctct tttacctcat tcatgaaaaa
     3781 gaagtccata ccctgagaat tatcaactca cgcatcgact acctaaacca actcgaccac
     3841 ctctttcgta catgtaggaa actattttcc tcacaaataa tctcattata aaatccaata
     3901 aattttttta gctcacttga atattttctt tgtatcgttt tatcagcttc aatctgatct
     3961 agacttgtta ccttggaacg acttgaaata acctttataa aataacactt aaggctttca
     4021 tcatctcgta taaatttttc aatagtgata taaaaagctt tcatattctg tttgtaatca
     4081 gatatcaatt gattaatttt atcattctga tgaagattcg ataccataat atatagcgga
     4141 ttgaaataag atgagaacaa atcgattggg aaagtaaaat taatttctat aaatgtttta
     4201 gcaattgttt cgtactattt tagattcagt ctactataca taaactaacc tcctcattat
     4261 tagcaaggat tctactgatt ataacctaat tcttagacta cttcaagact aactgtccaa
     4321 taataatcta cagataaatc atccactctt aataaaattt tattcaatcc atctactcat
     4381 tcccaaaagg ttgctgtata atgcaagaca tttttcttac tgattttact tttccttacc
     4441 ctcaatttag tgagctaata aattattctt cttcaaaagg ttgagattta tctagtaact
     4501 ctaaaacatt aatggtaggt agcaacattg cttcactgct atcaattgcc gaaactattg
     4561 aaacaataga acgtaaataa tgataaagaa tagcagtacc atttacgtat agaatatcgg
     4621 tgatattttc atctatattt atttcaaaat atcctattac agttacagat atttttttca
     4681 tggcatcttt gtcaactaaa gaaacactaa gttttacggc tccatgacta taatcatctg
     4741 tatgaccaac cttaactatg ggatataata tatcgaaggt aaatgtgaac aaactgatta
     4801 ggaaatttaa accaacttct aacaatctgt tatactaaat gaaaaccaaa gagcaaacta
     4861 ggaaactagc ctcaggttgc tcaaaacact gttttgaggt tgtggataga actgacgaag
     4921 tcagtaacca tacgcacggc aaggcgacgt tgacgtggtt tgaagagatt ttcgaagagt
     4981 attagaaagc tcgatggact attccagatt cattccacta gatttcgaaa tcgagtaggg
     5041 gataatctct agcccctctc acaccaccgt acgtgccgtt cggcatacgg cggttcaact
     5101 aactgttaac gcatgtcgtt caaggtaata atccaaacac gaaaccagtc cacgtttttc
     5161 aaggactggt tttgatatag cacgtttaag taccgacttc tgagctacta tagtagattg
     5221 aaactagaat agtacatctc ttcttctaaa acattgttag aaatcgattt ggctgccctg
     5281 atcgattcgt cctactctta tttcatttta ctataattga tagtggtcgc cccagccaga
     5341 taccttatcc gctatatagg ccttattatc atgttcctgt tcgtagagcc acgatttcgc
     5401 tatcccttcc tctgacgatt cttatttcct gcgtcagact tgggaatcgc tattgggttc
     5461 accggtagca ggtgcccacc gaggacttac acctcagata tacgacatgc ccgtcgtaca
     5521 tcaaaaaaag ttgagacata gcgtcttcaa cttttttaca ttactttaac tactgattaa
     5581 agtgagttta cgtcaacttt gataccaaca ccttgagtag ttgtgatagt caagtttgtt
     5641 acgtaagttc ctttagctgt agctggtttt gctttttgga ttgtttcgtt gaaagcttta
     5701 aagttttcaa ccaatttttc agcttcaaat gatactttac cgatgattgc ttgaacgtta
     5761 cctgcacggt cagcacggta agtgatttta ccacctttag actcttcaac tgctttagca
     5821 acatccattg ttacagtacc agttttaggg tttggcatca agttacgtgg tccaaggaca
     5881 cgtccaagac gtccaacaag acccatcata tcaggtgtag cgataactac gtcgaagtcc
     5941 aaccaaccgt cgttgatttt agcaacaagg tcatcttcac caacaaagtc tgcaccagca
     6001 gcttttgctt cttcagcttt tgcaccacgt gcgaaaacaa gaacgcgtga agttttacca
     6061 gtaccgtttg gcaataccat tgctccacgg atttgttgat cagctttttt aacgtcgatg
     6121 ttcaagttgt aagcaacttc tacagttgcg tcaaattttg caaagtttgt ttcttttgca
     6181 agtgctacag cttcttctac gctgtatgct tttgtgctgt cgattttctc aagagcagca
     6241 cgaagttgtt tgcttttttt agccattttc tattctcctt gtaagtggtt caatcgattt
     6301 tcatctccca cgtcacttct cgaaatgatg aagtcttgcg ggttttcagt ctattagatt
     6361 cttttcctac ggccttaagc tcccttgctg tacccaagta caagcatcag tcacttgcct
     6421 agtatgaaaa gcaactaata gactgctgtg agattttcta ctgtgttatt gattagtcaa
     6481 taacagtgaa tcccatagaa cgagcagtac cttcgatcat acgcactgca gactctacgt
     6541 ttgctgcgtt caaatctggc atcttagttt ctgcaatttc ttgtacttgt gcacgagtaa
     6601 ctgtagcaac tttagtttta ttaggtgtac ctgatccttt ttcaacacct gcagcttttt
     6661 tcaaaagaac agcagctggt ggtgttttcg taacgaaagt aaatgattta tcttcgtaaa
     6721 ctgagataac aactggaatg atcataccag cttggtcagc tgtacgagcg ttgaactctt
     6781 ttgtgaatcc catgatgttg ataccagctt gaccaagagc aggtccaacc ggtggagctg
     6841 gtgtagcttt accagcaggg atttgcaatt ttacaagttt ttcgactttt ttagccattt
     6901 ttaaatcctc ctttgtggtt ttggcggtaa ttagagattt ttacctccca caagtatgtt
     6961 tttcacatac ccatctatta tacactattt atctggaatt gcaagagaaa agtttatttt
     7021 ttaatcgacg taatctccac cttcaaagcc gaaatactct tccaaactga ggccactagc
     7081 tgcaatctct ttagcctctt ttccgacata acgaaggtgc cattcctcag ccatatagcc
     7141 tgtttccttt tccttacctt tgagataacg tacaacaaag ccataatcag ccgcatgatc
     7201 caagagccat tgggccgctt tttcttctgt caccaaatca ccatttgtcc caatcacatc
     7261 aaaggctaaa cctgtctggt gctcgctata gccaggacgg gcagaataac ggtcggcagc
     7321 ttctttccca tcttgattga cataatcttg atagagcttg gtctgagttt cataacttct
     7381 aaagccactg taatgatcgc taatggggaa acctgcctct tgcatagctt tgatgagctt
     7441 gaccaactca gccttggctg ttggattttc ccctggattg tagtcttttg acaatggata
     7501 gtgtttgttg gctacgatga tttcatcgta tttcccttga atgctgtaat agtctccttt
     7561 gttaaccact tctgcttttt tctgggcagc tccttgagac ttacttccta ctgttccatc
     7621 agctttagca gtttgctctg tcttagctgc tccatcttca ttttttgctt tttcttgtga
     7681 acaagctgct agactcaagg ctagcaaggc tgtcaagaca aggtatcttt ttttcatctt
     7741 tactccttta tttctaatag tttatctact tctgatgata aacgttcgac taatctttta
     7801 atctcatcag gttttgattg gcagatttct gctgtcattt cttcaaaggg aatccaccat
     7861 actggaccac gtccattgag gccataacca ttcatatcac ctcttcgtct aggaaacaga
     7921 tgccaatgga gatgagcatc gccatttcct agtagttcga tattcatttt ctcagcagca
     7981 aaggccttgg caactgcctc ttggaccaca ctcatttctt ctagaaaacg tattctagtt
     8041 ttcttttcta aatgatgcaa ttcgctgaca tgttccttgg ctagaaagag actatagcct
     8101 gcaaaatact ggtggtctcc aatcacaaga tagcctgttt ccaactcttt gacaaaatag
     8161 ggattttctc ccttcttgat gagctcaatt ctctggcaaa tcaaacacat attagtctac
     8221 caatgcactc ttaagatagg catcgaccat tcgttctgtt gcgaccaccg agtcaatatg
     8281 agtgcgctca taagaatgac tagactcgat acccgcacca agaagggcat gcttgacctc
     8341 tgcccctgca gacatagccg ctgaagcatc cgaaccataa aatggataga tgtccagctt
     8401 aaaaggaata tcttgctctt tagccaaggc aaccaagtgt tgacggaagt catagtgata
     8461 aggacctgag gcatccttga cacagataga tactgtgtac tcatttgtct gctggtcatc
     8521 tcccatagct cccatatcca cagccagata ttctactacc tgagcaggaa tgttagaatt
     8581 agcaccatgt cctacttctt caaaaactga aaaagcaaaa tgagttgtta ctggcaattc
     8641 aatcttctct ttcttataaa tacgaagcag gttgagcaac atcgctgcgc tgaccttatc
     8701 atccaaatga cgagacttga taaaacctgt atcagtcaca acagttcgtg gatcgaagct
     8761 gataaaatca ccgacctcaa tcccaagagc acgagtttct ttttcattgc ttacttttac
     8821 atccaaacgc acttccatat tgtcctgcgt gcgttctgca gttcctgcat ccttgtagac
     8881 atggcaagaa gtttggtgga tgaggatggt tcctaatacc ttttgacctg tgctagccac
     8941 atgaacggta cagttttcac cttcaatcat gttccaagga aaaccaccga tacggtccaa
     9001 tttaagacga ccatctggtt tgacagcacg aacaatagca cccagtgtgt ccacatgggc
     9061 agtcacatag cgatgttgct catcattttg acctttgatg gtcacattga caccaccctt
     9121 ggctgtgcga actggctggt aaccaaaacc ttctagagtc ttgactaaat aattcgaaat
     9181 ttcacgagtg aagcccgttg gcgatgcgat ggctgtcagt tctttgatat attctactgt
     9241 ttgattcatt tcttcacctc tttcgctacc tattataaca catttatcat cggataaaaa
     9301 aagaaaatca ctcctgtaga cttggctaca aaagtgattt aagtgattat tccatttcaa
     9361 aaacatcgct ttcttgcttg tttggtagaa ccaatgagag caagattcca acaatggctg
     9421 gcaccaacca tgggagagat gccttggcaa aaggaagaac gctaacaaga tttgcaagaa
     9481 actcaacctt aaacgagctt cctagtacgc ttgcaatggc aataactgta accacagcaa
     9541 ttgtcaactg catacctggt tttgaaaggg caacaaattt gttgacaatg acaatcataa
     9601 cgatagcaat cgtgattggg tacaagataa ccagtactgg aattgagtac ttgataatcg
     9661 catcaagacc caaattggca atagcaaatc caatcaaggt aaaggctgtc gcataaacct
     9721 tgtagctgat ttgtgggaag cgctcattaa agaactcagc tgttgacaca atcaaaccaa
     9781 cagtcgttgt gaagcaggtt acggtaacca tagctgcaag gaagagttga gctgttgagc
     9841 caaagatttc ttgagtggct tgtgacaaga tgtaaacacc tggtgttcca cccttcatcg
     9901 cttcagctgg tactgggaaa tgatttccaa gaaaacctaa accgatgtaa agagcgctga
     9961 aggcaagggc aacaacgata ccaacaaccc aaatagttga aatgtattct ttcttacttg
    10021 aaaatccaag ttgtttcaag gtttgaactg cgattacgct aaaggccact gaggcaaggg
    10081 cgtccaaggt attataacct tctaggaaac ctgtaccaaa ggcagaagct tgataagcag
    10141 ctgaagcagc ttgaggactt gttccaccat atttgatagc tcccagaacg accaagataa
    10201 caatcaaaat tgcaaagact ggcgttaaaa tacgtccaat gcggtctaag atttttgatg
    10261 gattaagcga aatcaaatag gctgccgcaa aatacagaac cgtaaataca atcaagccaa
    10321 gtcctttatt tgcatccgac aaaagggggc taatccctac ttcgtaagct gttgtagcag
    10381 tacgtggggt agcaaagaat ggaccgattg acaagtaaag aactgagagg taaagagtcg
    10441 caaaccaagg cgctatcttc gttgaaatct cgtagatata tcctttagga tttagcgttc
    10501 caataataag ggtcaagacg gcgataccaa cgcctgaaaa gacaaaacct gcgatggcag
    10561 gaagaaaatg ttctccagat agagcaccta gagaaggcgg aaaaatcaag ttccccgcac
    10621 caaaaaatat tccaaacagg agcaaacctg ttagggtacc ttttttagcc ataaaaatct
    10681 ccttcatatt tataaaatac tgatctagta taccacgatt aggagtctga aaaaagcatc
    10741 acgaggcaaa tattaaatgt tttcaatttt cttaaaaata agaattatct aaaaataaaa
    10801 ctctcctacc cagtccacac caagtaggag aaatgcaaaa ttttaaagtt cttcaaaggc
    10861 taacatgcca ccctggacat tgataacatt ataaccttgt tctaatagga attggcaagc
    10921 acgcgccgat ctcattccag atttgcaaat aatataatgc aagcgatctt tgtccaatta
    10981 atcataacta tcagccaatt gactaagcgg taggttgtgg gcaccttcta aatgaagagc
    11041 tgcaaactca tccacttctc tcacatccac tagagaaagc tggtcgtttt ggtaaagctg
    11101 gtaaaatgcg tcaaaggcta tttctttcat tctttttctt ctaatactct tcgaaaatct
    11161 cttcaaacca cgtcagcgtc gccttaccgt gcgtatgtta ccgacttcgt cagttttatc
    11221 tgcaacttca aagctgtact ttgagcagcc tacgactagc ttcctagttt gctctttgat
    11281 tttcattgac tataaaatgg ttttaattct ttttttcaaa tctggcacta cttctgcctc
    11341 aaaccaagga tttttggcca tccagatttg atttcgtggt gatgggtgaa ctagcggaaa
    11401 ataggctggc agatagtctt tatagtgttt caccctctcc gttaccttcc cactgatttt
    11461 ctcctgtaaa tagtaggctt gggcatattg cccaatcaag agggttaact gaatatcagg
    11521 caattcctgt aagagctgcg gatgccattt ttctgcaaaa cctgtacaag gcggaagatc
    11581 acccgacttg ccatgtcctg gaaagtagaa atccataggc aaaacagcaa aataacctga
    11641 attgtaaaag gtatcttcat ccacacctag ccagtcccgc aaacggtcac cacttttatc
    11701 tttccagtaa aggcctgctt cttgagtttt aagtcccgga gcctgaccga tgatattgat
    11761 gcgagcagtt tttggcgctg caaagagagg ctcaatgcca cgctctgtat agctggcatt
    11821 ctgcgaatcc gccatgatag cctgtttgat tctttcgatt tgagacatct actttccctc
    11881 caaaaagaag tccaagcata agatctcaga cttctatcgt tttatttgat caattcgtaa
    11941 atagcttcgg cataaattgc tgctgctcgg aagagatcgt ccaaggcaat aaattcattg
    12001 gcttggtgca tggtatcaat tgagtctggg aacatagcac cataggcaac tccgcgctct
    12061 aacaagcgac caaaggttcc accaccgatg acttgttcat gacctttaag gcctgtttgt
    12121 ttttcataga cattcaacaa ggtttgcaca agtggatctt ccattggcac atagtgaggg
    12181 gtatgaccat gttctgatag actgacagaa gcaactggca agttttctag gattgacttg
    12241 atttgttctg gacttgttcc ttttggatag cggatgttaa gggcaatggt attatcagca
    12301 cttgtttcat cgaagcggaa gacgccggca ttcatagaaa gagcacccat cttttcatcc
    12361 acatgagcaa tcttgagatt ttcaccctca tgatcgttca agagaatttt acctgcgatg
    12421 tcaaggtagt ctttggctgg accagcaaag ccaaactggc tgaggaagag ggcaaggtaa
    12481 gttgcgccat tgacacctga agcaggcata gcaccgtggg ctgatttacc aatgatcgtc
    12541 accttgtatt ggccagcttc ttcttggagt tctcctctaa gtttgtgttc tgcaacaaag
    12601 gcatctagtt tagcttgcaa gtctgtcaag tcacctgaaa cgactgctgt tgctgattct
    12661 ggtaccatat tttcacgtaa accacctgta aagctgtgaa gacgggctgc acctgtattt
    12721 tcacctgcaa agtggaggta ttccgtgatg tttccttttt caccattgat gattggaaat
    12781 tcagcatctg gtgagaaacc aaagtctggc ttggcgagtc ctacgtgctc gaagtagtag
    12841 tccatatctg cccagcctga ttcttcgtct gttccaacga tgaagcgaac tttcttagaa
    12901 gttggaaggc ccaattcttt gatgattttc aaaccatagt agcaagctgt tgtaggtccc
    12961 ttgtcatctg aagcaccacg cgcataaagg cgaccatctt tgatagttgg tgtgtaaggg
    13021 tctgtgtccc aaccgctacc agctggaacc acgtccatat gggcaaagat tccgagaact
    13081 tcttctccat caccaaactc aaaatgtcct gcatagttat caacattttt agttggataa
    13141 ccatcacggt ctgcgatttc aaggaatttt tccaaggctt ttactggacc aggtccaaat
    13201 ggatgttggg catcagcctt gctatcatca cgttctgagt tgatttccaa aaggctaaac
    13261 aagtcagcca agaggtcttc tttgcgtttt tctacttctg ctgtaaaatc aattgctatc
    13321 attttttctt cttcctatct tttttcgatg atttcatcta ctggcaagcg gtagcttggt
    13381 tccaatttgt cgtctgtgta acccactgtg atcaagagtt ctgggcggaa acggtcttca
    13441 atttccaaaa cctcattgac ttttgatttg tcaaaaccaa ggataatatt ggaaccaatt
    13501 ccttggtctg taagagcgag aaccaagttc atagcaacca aacctgcatt gagtgctagg
    13561 tagtcgctga cttgttgttc attgtagcgt gcaaattcag ctggcaaatt tttcatgaag
    13621 tattgaagtt gttcttctga gaaattgtta gcaccaccaa ctcgggcaat cttacgagcg
    13681 cgtttggcaa ggtctgtatc tgtaaatagg gcaatggtta caggtgctga tgatacctgc
    13741 tcaaagtttg aaccataagc caactttgcc agttcagcat ttttctcacg aacaactaca
    13801 aatttccaag gctggctgtt gtgggcgctt ggcgccaagg ttgcaatttc gatagccgta
    13861 cgcacatctt ttagatcaac aggcttatca gtgaaatgct tggtcgcatg acgtttttta
    13921 tttaattcaa gaaatttcat aatcgatttc cttttctaat tctactgctt ccattctacc
    13981 ataatttgaa agagcttgca gggatttttc atgattaagt ttttctatca cagacataaa
    14041 agatatatat tggtttatca ggaaagtttc tgataaacta gcaagtactt tacatttgaa
    14101 tggagacagt atgaaaaaat ttagcctatt actagctatc ctaccatttt tggttgcctg
    14161 tgggaatcaa gctacaccca aagagactag cgctcaaaag acaatcgtcc ttgctacagc
    14221 tggcgacgtg ccaccatttg actacgaaga taaaggcaat ctgacaggct tcgatatcga
    14281 agttctaaag gcagtagatg aaaaactcag cgactacgag attcaatttc aaagaaccgc
    14341 ctgggaaagt atcttcccag gacttgattc tggtcactat caggctgcgg ccaataattt
    14401 gagttacaca aaagagcgtg ctgaaaaata cctttactcg cttccgattt ccaacaatcc
    14461 cctcgtcctt gtcagcaaca agaaaaatcc tttgacttct cttgaccaga tcgctggtaa
    14521 aacaacacaa gaggataccg gaacttctaa cgctcaattc atcaataact ggaatcagaa
    14581 acacactgat aatcccgcta caattaattt ttctggtgag gatattggta aacgaatcct
    14641 agaccttgct aacggagagt ttgatttcct agtttttgac aaggtatccg ttcaaaagat
    14701 tatcaaggac cgtggtttag acctctcagt cgttgattta ccttctgcag atagccccag
    14761 caattatatc attttctcaa gcgaccaaaa agagtttaaa gagcaatttg ataaagcact
    14821 caaagaactc tatcaagacg gaacccttga aaaactcagc aatacctatc taggtggttc
    14881 ttacctccca gatcaatctc agttacaata acactcttcg aaaatctctt caaaccacgt
    14941 cagctttatc tgcaacctca aagctgtgct ttgagcaacc tacggctagc ttcctagttt
    15001 gctctttgat tttcattgag tataagatat actaaaagcg attggaccag ccaatcgctt
    15061 ttttagtttg cattggctat tttaggaaac tcttacaaaa aatcaaaaaa attcttcaca
    15121 tcctctacat acccatgctt ttctattaag ctggctaaaa gttccagatt gtgcccctga
    15181 tagttatcgt cacgacgcag ttcttcatac atttcaataa agggaagccc cttggacttg
    15241 gccaattcta actcagcctc gtaatcataa gcaactttac gaaattggat attgaccaat
    15301 tccccatctt caacttctat cacggcatac tgggcacggt gattttttaa cgcctcccaa
    15361 ttaaaatagg gcatgccaat cgaccctgga ttgatgattt gttgcccttg acttccataa
    15421 cgaagcaact gcttgtgaac atgaccataa actgccacgt ccgtttccgc atctagcagt
    15481 tggtcaaatt tctctgtatc attctcaact agcaagtcac caccatagtt cttatttggc
    15541 aaattatgag agatagaaaa gcgcagtcca gcaatttctt tcttttccag caaaggcaag
    15601 cttcgtagcc agacagtcgt tgcaggatcc attcgctcca tcaaaaactg agtcattcgc
    15661 atgagctgga tttcctgtgg gtcttctaag ccatattgcc catctaaagc ctcaaggaca
    15721 caatcattcc aattgcctcg aacacttgcc gtgataggaa gttcctttaa cagagcgacc
    15781 aagtcatttg cacctgaacc agggaggaaa atgtctccca tgagccaata ttcactggct
    15841 ccttgagttt tagcatctgc aatcactgct tctagcgccg tcgcattgcc atgaatatct
    15901 gataaaattg cgattttatg gtttattgtg gtttccttcc gtttggtaat ctactctttc
    15961 ttccgccact tgaagcaaga tttctgtttc ctgcgggttc aactttcttt gcacagcctc
    16021 tgctactgct cttggtactc caacttcgac aatctcatcc acactggctt ccttgatttt
    16081 ggtcagagac ttgaagtgcc tcatgagatt ttgcttgcgt ttaggtccca gaccatcaat
    16141 cccatccaat tgagatgaga aagaattttt ggagcgcagt tggcggtgga aggtaatggc
    16201 aaagcggtgg acctcatctt gaatgcgttg gaggaggaaa aattcctgag aattgcgaga
    16261 caagtccacc acttccagcg gatctccaaa gagcaattca tgggtttggt gcttatcatt
    16321 cttttgcaga cctgcaattg gaatatccaa gcccagttct tcttggatga cttgcttagc
    16381 aatattgact tgaccttgcc ccccatcaat cacaatcaaa tctggaggag tcaaagcctc
    16441 acgctgtact cgaccatagc gtcttcgaat gacttctctc atactagcat agtcgtccgg
    16501 cccaacaacg gtttttatct tgtacttacg gtaatctttt ttacttggcc tgccgttaac
    16561 aaagaccacc atggctgaaa caggactggt ccccatgatg ttggagttat cgaaggactc
    16621 gatgcgaact ggagtcggaa tttggagcaa acgtcctaga ttttcaatag ctccttgggt
    16681 cttttcgact gatttttcta gcaggttaaa tttctgctcc agactaacac gtgcattttt
    16741 tatggctaga ttgaccagct gttttttctc tccacgttgg ggtttgagaa tcttggtatc
    16801 caccaaagcc ttgacagctt cttcgtcaat atcctgcgga atcagtacct cattgggaac
    16861 taggtgagat ttttcttgat agaattgtcc cacataggtc aagaaatcct catctggatc
    16921 attgaagtag gggaagagat tgacatcgcg ctcgatgagc ttgccctgac gaacaaagaa
    16981 aacctgcaca cacatccagc ccttatccac atagtagcca aagacatcgc gattttggag
    17041 atccttagcc atgacccgtt gcttggttcg aagcgttcca atagcctgaa tcaggtcacg
    17101 gtattccgcc gcacgttcaa actccatact ttgtgctgct actgccattt tactcttgag
    17161 atcatcgatg attttgtcat cctgaccttt cagaaaatca gacacctcct gagccataga
    17221 cttgaaataa gcctcatcct tcttacagat ggtgtgggcc atacactggc cgatatggta
    17281 ataaaaacag accttagagg gcgggttggt acattttcga aaagggaaaa tcctatctag
    17341 aagtcgcttg atttcattgg ctgcccccac atctggataa gggccaaaat aaagaccacc
    17401 gtcctttttg acctgacgag taatgataag ccgtggatag cgctcattgg tgattttgat
    17461 gaaaggatag gacttgtcat ccttgagcat gatattgtac ttgggcttat tttccttgat
    17521 caagttgatt tccagcagaa gcgcctcaat attggactca gtgacgataa attcaaaatc
    17581 cacaatttca gacaccagag cctctgtctt ggtatcatga attccacgaa aataggaccg
    17641 tactcgatta cgcagatttt tagcctttcc tacatagata atggtgccat ttttatcctt
    17701 atgaatgtag caaccagggc tggtcggcaa gagctctagt tttgatttaa tcaagttgtt
    17761 catagttcca ttatagcaaa aaaagtaggg aaagatagta ccctactcac tagtctcata
    17821 tatttttcgg aggtttgcaa catcctcttc ctggatacca taaaaggaac ctgctggttg
    17881 catgacagac ttctcatctg tatggtccaa gccaatcgca tgacctaact catgttctgc
    17941 cgtatggaca aggcgttcat aggagtagcc atagtatgga ttggacaaat aataatgatt
    18001 caaccgcacc gttacggaca agaattgccc tgttaagaga ttagtttgac tttccgcctc
    18061 tcctgccaca ggagtgcctc cgtcgttcat ctccgtagcc gtaatatccg ccttactaga
    18121 ctcagtcacg agttcaaagt taaaagcacc agtttgattc cagttctgga ttgcttctaa
    18181 ataagcctct tgaaagcgtg aatccatctg cggatccagg taaatacgag cagaggcctg
    18241 tgcccacctt ccttcagaat gctggtgact atctgtctgg cttaacttag gcagttgccc
    18301 tgttttctcc cattggtcaa tactttgttg acccattttt actgaccgtt ctgcttgctt
    18361 tagcgctcct tgaaaatccc cgttcagata ccagagaagt ccgaaagcaa gcacacataa
    18421 gagcacaact atccaaacca gacgccaaaa caaacgccac acaaaagaaa agaaagcccc
    18481 tatcaaacga aaaagccagc gcatgtctct ccacctttct agcaaataag aattatttta
    18541 ctaaaagaag ctaaaagaaa tctaaatact gactttttca tcttaacgtc ctactatttt
    18601 tttgagtaac tggatagctt tgtattttaa aggcgatgga tggtaacgga aagtacctgc
    18661 tttgcgtaca atatagccat taaaattctg tttaaaacgc aaaacaccat cacttccatc
    18721 aaaaatccct tgaatgccta ggaagttgta tttaggtatt ccacgtttta tgctttccaa
    18781 cataacatat ttttgaagca gtgcaggggc atagaactta ttaaactcag tgtaggaacc
    18841 actaaagaga taagtcgttt cctgaggcat ataaacaaat aaactcccag ctaaaacaat
    18901 atcttcttct ccatattttt caatcaagtc tcgcgcttct gcttttcgaa cttcaaacgt
    18961 ttcaaattga ctagaatatt ctctcagttg attttgtttt ttctcagaat gaggattttt
    19021 actcaaatca agtcgcaact tgtccaagtt ttcttctagt ttactttgtt caccttgcaa
    19081 tttgctcata tactccgaaa aattcaagct tgctatgaga aactccgctt gttctccaaa
    19141 agtatcataa aaatgctcat aatattctaa acttttatca ctatattctc tacgttcaga
    19201 ggtttctttt gttatattct taaaaatcga tagttcttca cgttttaact ttttcaaccg
    19261 aatgccaaag gtttcagcct ttttcaccaa gggtttaccc tttttgctaa aacttttaag
    19321 caaactcttt tcagttaatt cagttaaatc tttatagtat aaccaatctg gttctccacc
    19381 tgggtaacct gttgttaagc catcaaattg ataacctaaa tcagtcaaac cttgaataat
    19441 actttttttc tcagcatcta ttggattacc ttggctatca aaagtttgat aagtttcata
    19501 aggttttaca agcaactcta atacaccatt ttgcttggca tattctttta actctgcata
    19561 aaaaactgga agagcatctt gttgggtata aatcggcccc gaattgagtt ccatatgcag
    19621 accacccagc atgggcaagc tataaaccag agctgcaact tgaatttctc cttcttgttt
    19681 caaagcaaga taaacaattc gagcccctct tttttctagc aaatccccca tctggacaga
    19741 ttgcataaag gaacgagaag aaacctgatc agaataagtc tgaaactctt ctttcgtgag
    19801 tgttgttagt gccatatact tactttctat gtttttttct taatgtttta cggaaatcaa
    19861 gagcaagtct taacagagga tagagaggat gagtgggcat tgtaaattca cccaagtatt
    19921 cttcaatcgt tggattaaat ttttccttaa aatgataaag tccaccattg agagagtttt
    19981 caacaccacc taaattttgc cagaccatac ctcgctcaaa ggcatagcga gccgtttcat
    20041 accatgttaa aattggtgca ttgtaacgtt taaaatcatc atccatacca gcatatatat
    20101 tgacagaggt agtaccaaat tccaaactca aagtagccgc taaaggaact ctcgcttgac
    20161 ctacatctat atattcctgc aagaaggtca attcctctaa caaacgttct ttttccttct
    20221 tctgcgcttc tacttttgaa gttcgagtcg actcagtaaa ggtctcttcc aaggctctat
    20281 ttttcgctaa ctgttcttct aactcttgcg aacgtttaga aacatccaag gtggccaagg
    20341 tgatataggc cttgtcctta aaattatcta acaatttttt ataataggct tcattcctca
    20401 aatgaatctc ttttcgcttc tcagtttttt tcatcaactc cgaaaatgaa tctaatagtt
    20461 ccagtccacc atattgaatc tcaagccctt tgtttcgtgc tgttcgaata gcctgttttg
    20521 ttgacttgga aagtttatct tcttcaaaat tttccttgta tattttcgcc tgaatacgag
    20581 gttgaatggt gtctcccatt tcctccgttt ttcctgacca ccttactccc atttgttgca
    20641 aactatcaat aatagccaga ttttcaggaa attctgtctt ttcctgattg attaaacttt
    20701 gagataggca aatacttggg tcaaaagtca caaaaaccgc tctcttactg cgagcatagg
    20761 acttaataga ctgaatggca aaattcaaga gttctttatc cccataatcc aatataggtc
    20821 ctcttgggat gtaaaacatt ttatagccta gcggaagagt tctaatcaaa atactagctg
    20881 tcgccagtaa tttttcttcc ctgtaaacac caaacttctc atgttgccaa ttagacttaa
    20941 cttcctccca agcactactt tgtaatacat tggctaattc atgttctttg acaaactgat
    21001 catattctaa tgtgggaatg ccaatttgat aacggtacat ttcctactct ctttcctcca
    21061 gtattttatt actattctac tactttcgtt tgaaaagtct agtgaaaaca tattttattt
    21121 tagttctact ccccctatgc tgaagttcaa actaagtcag tctctcttct aatttgaaat
    21181 caattggtag ggttgttaaa aaaacttcca attgtttttc ccagtagtac cactcgtgag
    21241 ttccagcgct atggctatag gtcacatcaa aacctagttt tttgagattt ttcactgcga
    21301 gattattggc ttcgtacaag aaatcctgtt cgccacacca cgcccaaagt ttggtctttt
    21361 tatccgattt tttagccaga ctttcaagag aatagggact agttgtccag tctctaatct
    21421 ctccaaaaac acctctccag taggctggac ttcccagatt ttgactttca ggagaaaagt
    21481 tttgaaagct gagggcacct gaaaaactag ctgcatgaga aaaacgattt gtcgcaagag
    21541 ccagtttgaa gcagccgtaa cctcccatag aaagaccagc gataaaggtc ttttcacgct
    21601 tgctagtcat attagggaag aagcgtttca gaacctgtgg caattcctct gctagagccg
    21661 tgtagtagtc aaaaccatac tgggtatcgg tgtaccaacc attgctggta ttgggcataa
    21721 caacgatgag attagttcct cgaagcaagc gttctacatt ggtccgctta agccaactat
    21781 tatgatttcc agacatcccg tgcaaaaggt acaagacggg aatatcttca cactctggtt
    21841 cttccactcg attggcatca gggtagagga cattcacccc ccactccata tccaatactt
    21901 gtgagtaata ctcgattttc attactgcca tgattttctc cttctatttt tctataagaa
    21961 aaagccgaaa ctcgactttc tctctgttta tttcaacgat tattttgctt ccatgactac
    22021 tggtaaaata gctggacgac gcttggtttg gtcaaagaga tacttggtca aattatctcg
    22081 aaccttccct ttaagatctg cccagtcaaa gtcatctcct tgaagataat cttctaccgt
    22141 ttggttaatc aattctgaac tttcacggag aatatcgcga ctcttcttga gataaacaaa
    22201 tccgcgcgta tgaacacgag ccctagccac aattttcttc tcacgacggt tgactgtaat
    22261 agccacgatg aaaattccat cctctgacaa gatcttacgg tcacgaagaa caacatttcc
    22321 aacatcacca atggcattcc catcaatcaa gatatctcct gctgaaaccg atccagctgg
    22381 aacaaagtct ccattctcgt aagccatggt cgtccccttt ttaggaatga agatgtgttc
    22441 tggcaacatc ccaactgcca tggcagcctt agcgtgagca tccaactcac gatactcccc
    22501 ttggacaggg aagaggtact taggttgcaa aagattgatc atcagctgca aatcacgcac
    22561 atttccgtgc cctgatacat gtaaactttg ggtaatcaat ttgacaaccc cacctgcctg
    22621 ataaatcata ttttccacac gcgcaacaaa ggcttcttta gcaatagacg gagccgtagc
    22681 aatatagacc aggtccccat ccttgatttc tacataacga tggcgaccaa tcgacatctt
    22741 acgaagtcca ttgataggtt cacccatacg acctgtctca agaataatca actcatggtc
    22801 ttcaaagcga gacatatctt taggcttaat caagagaatt tcgttggcta aagacaactt
    22861 cttaagacga atcgctgtgc ggacgatatt ttcaatatca aatcctgtca agacgatacg
    22921 tcgacctgtt ttatccgcag cgtcaaaaat ctgctgaata cgagaaagat tactggaaac
    22981 agctgcaacg atgatacgac cttcccagtc agcaatagtt tgggtaattt catccctaac
    23041 ttcactttca ctagccacct gaatattgct gtctgcattg gccgaatcac tgaggagagc
    23101 caggacgccg tcacgaccaa tctctgccaa acgagcaaaa tcagttgcat aagattcact
    23161 agccgtttgg tcaaatttga agtcacctgt ataaacgatg cttccttccg atgtcttcaa
    23221 gacaattccc agactctctg gaacggagta agtcgtaggg aagaaggaaa ccactgtccc
    23281 accaaaatca atctccgtat tctcatcaat gacatggaaa tcattaaatt tcttaacggc
    23341 atcatttcct ttgacaaaga gctttgccaa ctcaatggtc aactcagacc caaatacagg
    23401 aactttagcc tctgccaaga gataaggtag agcaccaatg gcatccgcat gcccgtgggt
    23461 caagaaaacc ccagcaatac ggtcgctatt ttcaaaaagg taatccatgt ttggaatcac
    23521 cacatcgacc cctaattgtt cattttcagg atattttaac cctacattca aaacaaaaat
    23581 ggactctcca atttcagcaa tgtacatatt ttttccattc tcacgcacac caccaagtgt
    23641 tgttaaactg atattactca tttttcctcc aaaatcttag tttatcttga ttatagggca
    23701 attctaccct cttattctaa aagttctgat actttcagcc gaatcttttc ctaccattat
    23761 accatttttt tgatgatttt caaaatgaag gtctgttttc aaaaaagagt tgatttccca
    23821 actctttcct aacttctact ctttttccat caaaaaatca taaatttctt gcaccgtacc
    23881 cagcgccatc atttcttggt ctttaacggt ttgtttgaga ttttggtaaa tttgactttc
    23941 tcctatctcc cgctttggcg cctctttatt gactgtcatc acaccatctt ttatcgtcac
    24001 aaagcctagt tcttcaaata cttgaatcat cttgaccagc aagatttgtt gaatattaag
    24061 atatgcagcc aaatctttca gcttgtagcg aatatcaaac tctgggaact ggtaaatagt
    24121 cttgtacaat ttagcaaact gatctctagt cccataacct gtcagataat aggtcttgtc
    24181 aatatcattt ttgaaataga cagcagagaa atgctgttcc tgaaaaatgg tcttcagctg
    24241 agtaatatcc tctggaatgt tttttacgac aacagcttca ctagccgcaa gatttggcag
    24301 ttctccagga aaatccaaga ctggaacacc ttctggcaag actgcatttt ttccacgaat
    24361 gttaaaaagt tgaacacctt ccactcgcgc atccaccatc atcaactgga gggcagtttg
    24421 gccattccat tggttgacag acaatttaac cgctaactct agattcttgg tttgagaaaa
    24481 ctctgtcgcc catctgcctt gaccaaaggc taccacttca aaactcgcct cacccttgga
    24541 aattttcagc tttagatggg cattacctgc ccccatagta cgagcacttt cgacctgaaa
    24601 attcttgata taaaaaatag gtttctgatt atccattcca aaaggagcta aacgttcaaa
    24661 acttttgacc gtttccaagc taagtgcctc caaatccaac tcttcatcta ggtttaactt
    24721 attcttgcca ccagcatctg cacctttttc acgaacataa tcttccaaaa cctgagataa
    24781 atctgagagt tgctcaactt ccagcgtcat acccgctgca cctgcatgac ctccaaaggc
    24841 gatgaagagg tctcgatggg gatccagagc ttcaaaaata tcgaccgctt ccacactacg
    24901 agcactgccc ttggcacgac cgtcttctat attaagaaca atgactgtct gtcccaattc
    24961 ttccaataaa cgaccagcca cgattcctag aaccccagga ttccagcctt ccttggccaa
    25021 gacctgaacc ttcttctcag gatccaccat ggtcttggct tcttcataga tagactgaac
    25081 gatttccttg cgctcttcgt ttttctggtg aatcataagg gcaatctcat gcgcttcctc
    25141 atcatcaaat ccagtcaaca aatcaatggc aggattggga tcatccaagc ggcccaaggc
    25201 attcaaacga ggagcaatct ggaaaccaac cgtttcttct gttacttcgt tggcagcaat
    25261 cccagccatg tccagcattt cttgcagacc aatgcgctgg gtatgaccca acatttccag
    25321 accatattga actaagatac gattttcatc cgtcagactc accatatctg caatagttcc
    25381 aatagcgacc aaatcaagca attccacttg cacttcttct aacagggcac aagccaactt
    25441 gaaagcaact ccacaaccag ccaaatattt aaaaggataa tccgcatctg gatgttcagg
    25501 atggacaata gcataagcat ctggcagggt ttcaggcatg gaatgatggt ctgtcacaat
    25561 gacatctact cccatagact gagccaatgc aatagcctca tgaccagcaa ccccattgtc
    25621 caccgtcaca atcaaggaaa ttccttcttg ctcgataaag tatttataaa cactagcatt
    25681 agggccatag ccatcggtaa aacgatttgg caggtaaact cggcactcag caccaagttg
    25741 ttccaaactt tccttcacaa tagaagccga agtcatgcca tccgcatcat agtctccata
    25801 aacgagaata ttttcccctt cttcaatagc ctgacgaatc cgctccactg ccttgtccat
    25861 atcatggagc agataagcat catgtaagtc ctccaaggaa ggttctaaaa acttcttcag
    25921 actttcttgg tcctgaatcc ctctctcaaa caataaccga gccacctcag gacccagtcc
    25981 agccttcttg gctatctttg taaaatccgc atcttctacc tgcagggcaa actgccattc
    26041 ataagtaggt gttatcaaaa agacatccac tctttctaag aattctattg cttcattata
    26101 acatgattta gacgttttct ctatccagat tgctttttta taacatttta tagtatattg
    26161 aaactagaat agtacacctc tacttctaaa atattgttag aaatcgattt gactgtcccg
    26221 atcgatttgt cctgttctta tttcactata gtgaattttt tcagatatgg tttgacaaga
    26281 acattctttc attgtagaat cgtgttataa aatataacac aaaggagatc tctcatggct
    26341 ttagtagaat ttaaaaacgt cgaaaaatat tacggagact accacgcact ccgcaacatc
    26401 aatctccgtt ttgaaaaagg acaagttgtt gtcctgcttg gaccttctgg ctctgggaag
    26461 tccactctta tccgtacgat caatggttta gaggctgttg acaaaggaag tctcctagtc
    26521 aatgggcacc aagttgctgg tgccagccag aaagatttgg tacctcttcg caaggaagtc
    26581 ggcatggttt ttcaacattt taacctttat ccacacaaaa cggtgttaga aaacgtgaca
    26641 cttgcgccca ttaaagttct aggaattgat aaaaaagaag ctgaaaaaac cgcccaaaaa
    26701 tatctggaat ttgtaaatat gtgagacaag aaagattcct atcccgccat gctatctggt
    26761 ggacaaaaac agcggatcgc catcgctcgt ggtcttgcta tgcatccgga actcctcctc
    26821 tttgatgaac caacatctgc tcttgatcct gagactatcg gagatgttct agcagttatg
    26881 cagaaactgg cgcatgatgg gatgaacatg atcatcgtta cccacgaaat gggctttgct
    26941 cgagaggttg cggaccgcat tatctttatg gccgacggag aagttttagt agatacgaca
    27001 gatgtcgata acttttttga caatccaagc gaacctcgtg cccaacaatt cctcagcaaa
    27061 attatcaacc acgaaagtga caaagtcaaa taaggaggcg cctatgaaaa aaaattcttt
    27121 ttatcagcat tattgattag ccttttcggc cttgctgctg ccaaaccagt ccaggctgat
    27181 actagtatcg cagacattca aaaaagaggc gaactggttg tcggtgtcaa acaagacgtt
    27241 cccaattttg gttacaaaga tcccaagacc ggtacttatt ctggtatcga aaccgacttg
    27301 gccaagatgg tagctgatga actcaaggtc aagattcgct atgtgccggt tacagcacaa
    27361 acccgcggcc cccttctaga caatgaacag gtcgatatgg atatcgcgac ctttaccatc
    27421 acggacgaac gcaaaaaact ctacaacttt accagtccct actacacaga cgcttctgga
    27481 tttttggtca ataaatctgc caaaatcaaa aagattgagg acctaaacgg caaaaccatc
    27541 ggagtcgccc aaggttctat cacccaacgc ctaattactg aactgggtaa aaagaaaggt
    27601 ctgaagttta aattcgtcga acttggttcc tacccagaat tgattacttc ccttcacgct
    27661 catcgtatcg atgccttttc cgttgaccgc tctattctgt ctggctacac tagtaaacgc
    27721 acagaactac tagatgatag tttcaagcca tctgactacg gtattgttac caagaaatca
    27781 aatacagagc tcaacgacta tcttgataac ttggttacta aatggagcaa ggatggtagt
    27841 ttgcagaaac tttatgaccg ttacaagctc aaaccatcta gccatactgc agattaagga
    27901 ggacacccca tgatagattt atcatcttgg acagcctatt ttcaggattt tggacaattt
    27961 ttcaatggtt tcctctttac tcttgcccta gcgattggat cctttatcct cgccatggtc
    28021 ttaggaatct tctttggtgc catgtcaacc agtaaacgtc caattttacg cattttagct
    28081 cacatctttg tggaatttta ccaaaacact cccctcttgg tgcagtttgt tattgttttt
    28141 tatggcctac ctcttatcag tgaccatact atcatgattc caatttattg gacagctgtt
    28201 ctctgcatgg gactctatca cggcgcttat atcgctgagg ttattcgttc agggattcag
    28261 tctattccta gtggtcagat ggaggccgcc ttgtcgcaag gttttaccta tatcagtgcc
    28321 atgcgcttga ttatcttgcc tcagaccttc cgcatcattc tccctccatt gaccaaccaa
    28381 attgttaacc tcatcaagaa cacctctact gtagctatca tctctggagt agacttgatg
    28441 tttgtgacta agtcttggtc ggctctcaac ggaaactata tcccagcctt tttaggtgct
    28501 gctcttctct actttgctct atgcttccct gttgcccagt ttggtcgcaa gatggagcaa
    28561 gccaacaaaa aagcctattc actttaggag gttactatgg aatctatttt agaagtttta
    28621 accccagata acctagtctt tatctttaaa ggatttggct tgaccctcta tatttctctg
    28681 attgccatca tcctctctac tatcatcggt acggtgctag ctgtcatgag aaatggcaaa
    28741 aatcctgtct tacgcattat ttccagtatt tatatcgagt ttgtgcgcaa cgttcccaac
    28801 cttctctgga tttttactat ctttttggtg ttcaaaatga aatccacacc agcaggtatt
    28861 acagccttta ctctctttac atcagcagcc ttggctgaga ttattcgagg cggtctcaat
    28921 accgtagaca agggacagta cgaagcagga atgtcacaag gcttcacctc agcccaaatc
    28981 ctctactaca tcattctccc acaagccatc cgcaaaatgc taccagccat catttctcag
    29041 tttgttaccg tgattaagga taccagtctc ctctactctg ttatcgccct acaagaactc
    29101 tttggagcca gccaaattct catgggccgt tatttcgaac cagagcaggt cttcagtctt
    29161 tgcatcctga ttgccctcat ctacttcagc tttaacctag caatttctag cctgtctcat
    29221 atgctagcca aacgttggca acaagctgca gaataatact cttcgaaaat ctcttcaaac
    29281 cacgtcagct tcaccttgcc gtatatatgt tactgacttc gtcagttcta tccacaacct
    29341 caaaacggtg ttttgagcag cctgcggcta gcttcctagt ttgctctttg attttcatta
    29401 agtataaaca gccactctcc agttcaattg gagagttttt tgatgagagt agatatttat
    29461 agacctcaat ttgacaccat acattttcta tgataaaatg taacaaattc atttacaaca
    29521 aatcgaaatc taaatgaaat ggaattttct atgaaatcag tcaaaggact actctttatc
    29581 atagctagtt ttatcttgac tcttttgact tggatgaaca cttctcccca attcatgatt
    29641 ccaggactag ctttaacaag cctatctctg acttttatcc tagccactcg tctcccacta
    29701 ctagaaagct ggtttcacgg tttggagaag gtctacaccg tccacaaatt cacagccttt
    29761 ctctccatca tcctactaat ctttcataac tttagtatgg gcggtttgtg gggctctcgc
    29821 ttagctgctc agtttggtaa tcttgccatc tatatctttg ccagcatcat ccttgtcgcc
    29881 tatttaggca aatacatcca atacgaagct tggcgatgga ttcaccgcct ggtttaccta
    29941 gcctatattt taggactctt tcacatctac atgataatgg gcaatcgtct ccttacattt
    30001 aatcttctaa gttttcttgt tggtagctat gcccttttag gcttactagc tggtttttat
    30061 atcatttttc tatatcaaaa gatttccttc ccctatctag gaaaaattac ccatctcaaa
    30121 cgcttaaatc acgatactag agaaattcaa atccatctta gcagaccttt caactatcaa
    30181 tcaggacaat ttgcctttct aaagattttc caagaaggct ttgaaagtgc tccgcatccc
    30241 ttttctatct caggaggtca tggtcaaact ctttacttta ctgttaaaaa ttcaggcgac
    30301 cataccaata atatctatga taatcttcaa gccggcagca aagtaaccct agacagagct
    30361 tacggacaca tgatcataga agaaggacga gaaaatcagg tttggattgc tggaggtatt
    30421 gggatcaccc ccttcatctc ttacatccgt gaacatccta ttttagataa acaggttcac
    30481 ttctactata gcttccgtgg agatgaaaat gcagtctacc tagatttact ccgtaactat
    30541 gctcagaaaa atcctaattt tgaactccat ctaatcgaca gtacgaaaga cggctatctt
    30601 aattttgaac aaaaagaagt gcccgaacat gcaaccgtct atatgtgtgg tcctatttct
    30661 atgatgaagg cacttgccaa acagattaag aaacaaaatc caaaaacaga gcttatttac
    30721 gaaggattca agttcaaata agtaatcata ctctcctggg atttcccagg agagtttttt
    30781 atagccaaat gaaataaaac cggaacgatg gaattttggc attcaaatca attgataaga
    30841 atattttata gtggagtgaa ataggatacg aacaaattga ttaggaaaat caaatgaatt
    30901 tatagaaatc ttttagcagt tatgttgtcc tattctagtt tcaaaacgct atagaagcag
    30961 cattgtgcta gtctagattc agtttactat actaaaacga gtagcttgaa atcaaaaaac
    31021 ccaccctcac aggcaggttt tatctgtatt attcagctag attatgcttt accttctgaa
    31081 ccgaatacgt cgatacgttc ttcaaccgat gcttggatag cttttacacc gtcagccaag
    31141 aatttacgtg ggtcgaagag ttttttcttg tcgtattctg cttcgtttgc ttcgtagtca
    31201 cgagcaaatt tacgagttgc gttagcgaat gcgatttggc attctgtgtt aacgttaact
    31261 ttggcaacac caagtttgat agctgcttgg atttgctcat caggaatacc tgatccaccg
    31321 tgcaatacga ttgggaatcc tggaagagct tctgtcaatt tttgcaagtg gtcaaggtca
    31381 agaccttccc agtttactgg gtaagggccg tggatgttac cgataccagc tgccaagaag
    31441 tcgataccag tttcaaccat tgctttagcg tcttcgattg gagccaattc acctttaccg
    31501 atgattccgt cttcttcacc accgatagta ccaacttcag cttctactga gataccttta
    31561 gcgtgtgctt tttcaacaac ttctttagcc aatttaaggt tttcttcaac tggaaggtgt
    31621 gaaccgtcaa acatgattga agtataacca acttcgatac actcaagtgc atcttcgtag
    31681 tgaccgtggt caaggtggat agctactggt acagtgatac ccattgattc aacaaggtta
    31741 gcgatcaagt tgcgagcaac tttgtaacca cccatgtatt tagcagcacc cattgaagtt
    31801 tggatcaaaa ctggagcttt tttagcttct gctgcgcgca agatagcttg agtccactca
    31861 aggttgtttg tgttaaatcc accaactgca taaccgttgt cacgggctgc ttggacaaat
    31921 ttttctgctg aaacgattgc cattttatca ggcctcctgt atatttttat gggtcatccc
    31981 atttacattg ttcattttat cactttttgc caaaaaaatc tagtttttcc cgcagtttcg
    32041 attgattttc ttctaactcc atctatgtaa accctttctc tccctagtct tggacgactt
    32101 ttggaaaatc tataaagaag gttaaacgat tctcctccat ctcgaaacga taagctaatt
    32161 tttcatgttc taatagactc ttaaccacaa agagccccat accagacccc ttgaccttgc
    32221 gactggcatt gtcagaaaaa gactgggcta gtttttcttg ttcctctgag ctacagctat
    32281 tttcgataaa aagttctcct tctctttctc caattcgaac taagccacct ggaacagagt
    32341 gcttaatggc attgctgatg agattagaaa gaatcaactt cataactgat gggtttagat
    32401 aagcctgctg atgggtcaaa ctattgtcta tctggagctc tctttccttg gctagcaagg
    32461 cataatcttt gaccagattt tgcgtcatct ggaggaggtc aattgtttcc ctatcatctc
    32521 gcaattcctg cacagaagag agggaaagta tctgcagaac atggtgattg agttcatcca
    32581 caatccccaa ggcaactccc agatactggt ctctatcctt ataacgaccg atattctctc
    32641 tcatattttc gattaggatt ttcaaactag ccagcggtgt tttcaattca tgagaagctc
    32701 ctcgtaggaa ttcgaccttc atcttctcca gctggagaat ggcttcattc ttttcatgca
    32761 agtccgcaat aacagtcaag agatgctggt agaggctatt gatttgttcc ttgagattac
    32821 ctatctcatc cttagaatcc acgcgcaatc gcacttggga atccaggtcc atcatccgac
    32881 gggtcacccg cttgatttcc aagatcggtg caacaatagt ccgagcgtag atgtaggcca
    32941 ccaagaggga aatcagaaag gaggccagca aggtataggg aagaaactgg agactgattt
    33001 gctccgcttc cttttgtaaa tccatggaag ctagaaactg gagaatcata gtagcaccgt
    33061 cttgcgtttt cacctcgcgc tcctcaataa agagagaggt tgtctggcgg tctgtgtcca
    33121 gaggaagact gtccttgact tctaacttgt cctcggtcat ctcacctttg acggtcccct
    33181 tgatatcact agtctgggaa tacaagtcta acacttgctc gatactctgc ctatctttcc
    33241 cttctaggga ctgggcaatg gctgttgcct tttgaccaat ggtttcctga cgatgactca
    33301 gataagtcga aggaaaaaga aaataaatag ctaaatgaag gcagataacc agaacactaa
    33361 atatcgagaa ggtatagata aatatctttg caaataaacc tgttcgtttc attttcgctc
    33421 caatttataa ccaacattgc gcacagtgag gatacaatcc aagtctagct ttttccgcaa
    33481 ttccttgata taaacatcaa taacacggtc aaagggaacc tcatctgtcg ctttccagac
    33541 ggcatcgata atctgagatc gagtcaaggc ccggccttca tttttcacta gatagtccag
    33601 aatttccaac tctttggcat tgataggcac ttcttgacct gcgatgcttg cactgtagct
    33661 ttcaaagtcc accttggtat ccttgtaaga aaagattcgt cctgtatcgt agtagcgctt
    33721 gaaaatcgcg tccaccctca cttttaaaag ggagagggag aaaggttttt ccagatagcc
    33781 atctgccaaa gaggcaaagg cactcatctt gtattcctca tcttgaaaag ctgtcaacat
    33841 caagacagga acctgactgg ttttacgaat ctcagctagg acttctaagc cgttgagctt
    33901 gggcatctgg atatccagta aaaccagggc cacctcatag ctagaaaatt gctccagagc
    33961 ttcctgaccg tccgctgcct caatagtttc atagccacaa tccgtcaaat aatcactgac
    34021 cccctcacgg atcatctctt catcttctac aattaaaatt ttcatacttt aactgctctc
    34081 tattttttat ttttcttaga ataaatacct actctatttt ctattatagt ctcttgctgg
    34141 ccttttgtct gcaagcaact gaccactaga taaaacgttg tgaaattcct ttctcataaa
    34201 ttccataact ttagtatatt atatttaagc actaaagtac aaagaaagca actgaaagca
    34261 atgattttca ccactgcttt cggatttatt ttgaattgtt aaatagccat tcctatccac
    34321 tattcttgaa tagaaacaca agatgcaatc tttattctag actcattttt tcaaatttat
    34381 tcaccatcca gcaagagctc ttttggttgt tttctaagga gattgcttga agcaagcgcc
    34441 ataacgagaa ccactagaac caaggcaagg acaaaaatga tgataaagtc tgatgtctga
    34501 atggaaatgt ctaggctcga caaggtcttg ctaaagccat ctacttctgc accaccacca
    34561 aggttagagg cttgagccgc cttactagcc tgtttggcaa cacctgaagt cacattggca
    34621 aggacagtgt ttccaattgc acgggcagtg taattagcta ggaagtaagc agaaactaga
    34681 gcagggatag caatcaagat agattcggtg atgaattgac ccaagatact tgcctgcttg
    34741 aggccgatag agaggagaat tcccacttcc ttgcgacggg cgttgatcca aaggctgagc
    34801 aagagggcaa ggaggagaac tgagaagctc aagctacccc agaagaggag gttggccatc
    34861 ttgtacatac cagagataga ttgctcaaga gctgggtagt tagaggagct cttgacgagt
    34921 gtgtagctct tccagttgat accactgatg ccattcaact ctttcataac atcatccaag
    34981 ttcttgtctg ctgttacaaa gaaggttgcg tccccataaa tggctgtgtc ttctgtgtat
    35041 ccataaagtt ttgcagcagt gtgaatgtct gtaatagctg tgttttcgta aagttcttgt
    35101 gagtaggtta ctgctgactt attatgacca tcaaagagtc ccttgattgt cacttcaact
    35161 gtttccttgg ctcctttttc attatctgca tcgtagatat tagagtccag tttaaccttg
    35221 tcccctactt tccagccgtg tttggctgcc aagtccttgt gcaagaggat tttatccttg
    35281 tcgtcgttgg ttaagtgctc tccttcgact agtttataag aaccagagac aaacttgtct
    35341 tctttagagg agtcattgac acctgtaatc atcaagctac ttccaaaacg cttggcacga
    35401 tcagcagtga gattcttctt ggtttctggc gtttcaatca ggtcatatcc agtcaaatct
    35461 ccgatagcgt tgatacgttt gacataagac tcgatggcct tgttttcggt gatttttttg
    35521 atgtcttcac ccttgatatt cccagcacca cgaggcgttc cttggttgac gcgacgattg
    35581 atttgcatgg agaagctatt agtgatattt ttaaaggtct cctgagaagc cttggcagta
    35641 gctcccttga ttgacaagcc gaccaaactc aagctcgcca tgaggagaat aatcaggaag
    35701 atgacaatcg atttgaaaaa cttccttgta acataggcaa atgcgttgtg taacatagat
    35761 tccctttcta gattttgttt taatcattct atcaaaataa gctcaaatta tttactagta
    35821 ttgcgcgttt cagtcagttt cttatccttt aattcaagtg taatatctga cgcttgtgcc
    35881 acttctttac tgtgagttac gacaatcaca catttacctg ttttctgggc aagtgatttg
    35941 agtagttcga caatatctcc agcagtttta ggatccagat ttcctgttgg ctcatcagct
    36001 agaataactg gagcttctga gaccaaactg cgagcaatgg caacacgttg ctgttgacca
    36061 cctgataact ggagaacatt ccgcttgatc tggctttcat ccaaaccaag ctcaagaagt
    36121 gtatccttgc ttgccttttt gttgaccaag cggatatttt ccagcggaga aagataatct
    36181 atcaagttat aattttgaaa gaccagggaa atatggtgca tgcgatggta agaatagccc
    36241 ttcttacgaa tatcctctcc ttgaaaaagg atagaacctt caacaggact atctagacca
    36301 gcaagtaggg acaagagtgt ggattttcct gctcctgact ccccaataat actgtaaaat
    36361 tttccaggtt caaaattata atcgatctga tataggactg cttcagcagt attcttataa
    36421 cggtaggtaa catcttgtaa ttgtaataaa gtcatgattt ctccttctta actaatagat
    36481 gataaaattt ctttcggtga ttttctaaat aagaatagga aacaaagggc tacagataag
    36541 caactaagca gaactagaaa aacataggat tctgcaaaag ataagatgct agttgataaa
    36601 ctgcttgctt tggctagtgt atcttgtaag cttgcctgat ctccacttgc tagtagagtt
    36661 tggagtagat aacttgtgat tccgtttcct gcaacaaatg ctggaagcaa agctccaaga
    36721 gataccaaaa ctacctctaa acagaattgt aggaagatcg agctcttgcc ttttccaagt
    36781 gcaagtaaaa tccccacttc atagacccgt tctctcaacc agagagacaa aaccagaatt
    36841 aaggctccag ctcctgctat caacatccca taaaggaaga tggtcaagaa ggtttggaaa
    36901 gttgcaactg agtctttgat ttgttcaaaa gccttgtttt ccttttcgac ttggtagcct
    36961 tgattttcca aggccaagtt ttctacctgc ttcatgagtc cgtccatttc cttaggattt
    37021 tctacataga agcgtgctgc actgacttga gcttcactat tgcccaaaag ggtttggcta
    37081 ctttcatagt ctgtaaagac ttgattttca ctgaagtcag aagacaagcc tgtgaatttc
    37141 tcttgttttt taccagaaaa gatgccgata atctcaaact ctactgtttg tccttttcca
    37201 gattcagact gaccagcatc caagccaatc ttgtcatgaa gtgaaagacc gttcttctta
    37261 gccaattctt cgtggataag gattttcttg gaatcccctt tttgaaggtg tcgcccttct
    37321 tttagattga aagccgaact ggtaaaggtt acatccttgg atgaatcctc aagagccgtt
    37381 aagctaacca agttattgtc tgcagctgat aaatcatcac gctccacgct ctgctcacca
    37441 gtcactgctt ccttgtcttt tagttttgcg accgtctcaa gttcaggaga gacattttcc
    37501 agccccttaa tcttgcttac agatgctagg tctgacaact tgaatgtctg accattctct
    37561 atcttcttaa tagaaaaaga tgtattgagt gatttataaa gattgctttc tactgttttg
    37621 ttggacttca tcagagtcaa acaggctgaa attccggcca ataagaccaa taaaatcaga
    37681 aataaaataa aacttctcag tcgctttctg ctgacataag cccaagatct ttggattgga
    37741 ttcatttgtc acctccatat ttgtaagact attataaaac ccaaatatga aatgtttatg
    37801 aaatacgaaa aaaaatatcg agtaggggat aatctctagc ccctctcaca ccaccgtacg
    37861 tgccgttcgg catacggcgg ttcaactaac tgttaacgca tgtcgttcaa ggtaataatc
    37921 caaacacgaa acctgttcac gtttttcaag gactggtttt gatatagcac gtttaagtac
    37981 cgacttctga gctactatag tagattgaaa ctagaatagt acatctcttc ttctaaaaca
    38041 ttgttagaaa tcgatttggc tgccctgatc a
//
LOCUS       DAVBIC010000017        37451 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.017, whole genome shotgun sequence.
ACCESSION   DAVBIC010000017 DAVBIC010000000
VERSION     DAVBIC010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 37451)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37451)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37451
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.017"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            complement(<1..777)
                     /locus_tag="VQ664_000819"
     CDS             complement(<1..777)
                     /locus_tag="VQ664_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2789009.1"
                     /translation="MSKETVVYTKRREKIKDNILGYSFLAPALILLGIFLVIPVGMVI
                     YYAFTDYYLLTPDERKFVGLENFIRLTKDPIFLKSFLNTLKFVVWIIPVQLGAALGMA
                     LIVNKKRKGNMFFKVAFFAPVVMSLVVISILWLYLLNPNSGLLNAILNKVGIASQPFL
                     TSPKQAMYAIVFVSAWQGAGYQMLLFLGGMQNIPQDVYEAAELDGFSKWAQFRYITMP
                     LLKPTALFVLLTTLISAFKLIVQPMVMTQGGPLNSTITMVY"
     gene            complement(873..2183)
                     /locus_tag="VQ664_000820"
     CDS             complement(873..2183)
                     /locus_tag="VQ664_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HET2789010.1"
                     /translation="MRKGTMLSVVAGLSLAILAGCSGGTNSKQASSSNDIKVWVQFSD
                     ETNEGKAWQKVVDNFNQSGKSKYKVVTEYIPRSGSGGGYEDKVNAAITTNSLPDVITL
                     DGPNTAAYAKSKVITPLDDYLKDNNMDDVLDSIKQQGTYNGKFYAFGFSESNVGVYYN
                     KKMFKEAGIAESELPTLEKPWTWDEFNTIAKKLKDHYNKPAIDFRINSNDEMLPYAYM
                     PLIWSNNGSVVNEDGTKAEGYFNSKESVEAVQFIQNLVKEGYTTVSPVEKGFETGEYP
                     MLLSGSWTIADMNTNYKDIDFGILPYPVSSKTKKLVSPSGSWQLAVTTKSDKKEAASE
                     FVKFATNTESSEIISLGNSVLPIRKSTIENIKDKVSEPMRFLMEQNSKTAHARPVVVA
                     YPQVSRAFQQAMQDISYYEENPNVQKVLDTRTKEMQTAIDQSLK"
     gene            complement(2310..3305)
                     /locus_tag="VQ664_000821"
     CDS             complement(2310..3305)
                     /locus_tag="VQ664_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET2789011.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLRKVQR
                     AIKTLDYIPDNYARGMKKNRTETIALIIPSIWHPFFSEFAYHVEKELLKYNYKLFICN
                     ADSDSQNEIEYIEMLKQNKVDGIIGITYSDIDKYILSDLPFVSIDRHFSENVCYVTSA
                     NYKGGQTAAEELVRRDNKHLAFIGSINMYENETILRSKGFREKAKELGVDVYNFEMKE
                     PLINPEDQIRIFLQSHKEIDGIFTINDMMALRVISVMKELGKIAPDDYQIIGFDGLKT
                     SVDQSYLVSTIVQDIGMMAKESVAMILKMIKREEILEKRIVIPTYFGGDKTTKKI"
     gene            complement(3667..5148)
                     /locus_tag="VQ664_000822"
     CDS             complement(3667..5148)
                     /locus_tag="VQ664_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET2789012.1"
                     /translation="MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKD
                     DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQ
                     AESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSE
                     KYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME
                     VDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESL
                     FMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEF
                     ILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHL
                     VINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSS
                     YDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
     gene            5591..5755
                     /locus_tag="VQ664_000823"
     CDS             5591..5755
                     /locus_tag="VQ664_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HET2789013.1"
                     /translation="MGIIANVFAGLVGAYAGQSLLGSWGPSIAGMALLPSIVGAAIVI
                     TVVSFFTGRK"
     gene            5839..6405
                     /gene="amaP"
                     /locus_tag="VQ664_000824"
     CDS             5839..6405
                     /gene="amaP"
                     /locus_tag="VQ664_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HET2789014.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            6417..6587
                     /locus_tag="VQ664_000825"
     CDS             6417..6587
                     /locus_tag="VQ664_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HET2789015.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            6626..7234
                     /locus_tag="VQ664_000826"
     CDS             6626..7234
                     /locus_tag="VQ664_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HET2789016.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            7265..7468
                     /locus_tag="VQ664_000827"
     CDS             7265..7468
                     /locus_tag="VQ664_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HET2789017.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(7578..7856)
                     /locus_tag="VQ664_000828"
                     /pseudo
     CDS             complement(7578..7856)
                     /locus_tag="VQ664_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895264.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            8054..8341
                     /locus_tag="VQ664_000829"
     CDS             8054..8341
                     /locus_tag="VQ664_000829"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HET2789018.1"
                     /translation="MIVSLKTKSRKAKDMAESIQGWLAQFLVNLFKSITFDCGKEFSK
                     WKDISNHHDSESFFANLGCSRQRRLNEHSNRLLRCHDLPKQTDFNEVSQEF"
     gene            complement(8619..9389)
                     /locus_tag="VQ664_000830"
     CDS             complement(8619..9389)
                     /locus_tag="VQ664_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HET2789019.1"
                     /translation="MVEIIYFLIIIIASGLGSISGMGGGIIIKPLMDSFGYHSVSDIA
                     FYSSFSVFIMAIISTIKRFSQSKEIKWRLIFTVSFSSVLGGFLGHLIFQVLLSQLSVR
                     LVSIVQMILLFVMLLVSFVLTDFKKTYQFDKIGFYMICGLLLGLISSFLGIGGGPLNV
                     SLLMVFFSISIKEATMYSLAIIFFSQLSHLATIVVVTGLNQYHLAPVPVIFLASICGG
                     VLGTVVSKVLPENWVRYCFKGMLFFVMGMTLYNLFHIL"
     gene            complement(9404..10252)
                     /locus_tag="VQ664_000831"
     CDS             complement(9404..10252)
                     /locus_tag="VQ664_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formylglycine-generating enzyme family protein"
                     /protein_id="HET2789020.1"
                     /translation="MKMKKIKGGTFMMGTNSEEGFLDDFEGPQVAVSVKDFSIADTPV
                     TNQEFAQFVKETGYKTLAERQEWSFVFILFVPEAEREGYPHPAGAPWWLQVPNACWKH
                     PYGENSNLVGLEDHPVVHVALEDALAFCNWSGMSLPTEAQWEYAARGGRQSEYPWGDT
                     LLEGGYYHANTWQGRFPYENTALDRFIGTAPVYEFLPNDFGLYQMIGNVWEWCRNPRY
                     TLLASFNEDDYELPKYGIQDEEYAIRGGSFLCHCSYCNRYRVAARNGCISTSTSSHLG
                     FRCLKE"
     gene            complement(10249..11724)
                     /locus_tag="VQ664_000832"
     CDS             complement(10249..11724)
                     /locus_tag="VQ664_000832"
                     /EC_number="3.1.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arylsulfatase"
                     /protein_id="HET2789021.1"
                     /translation="MVQTKQPNIILIVVDQMRADALSLNSKDKLVSTPTLDMMASVGY
                     NFENAYSPVPSCVPARAALLTGLDQDKSGRVGYQDEVPWNFTNTLPKVFKDMGYQTEC
                     IGKMHVFPSRQRLGFDHVLLHDGYLHVDRKYDKAYGSQFDYVSDYLAFLKGKVGYDVD
                     LIDDGMDCNSWEARPWDKDEKLHPTNWVVSESISFLQRRDPTVPFFLKMSFEKPHAPL
                     NPPKYYFDMYMERLPQFLDLHIGNWEVLEKQIPSIYALRGKLKEDDQRRMVAAYFGLI
                     THIDHQISRFLTSLKEFRHDKDTIIWFVSDHGDQLGEHYLFRKGYPYQGSIHIPSFIY
                     DPAGLIAGNRGTIKQLVKIQDIFPSLVDLAGGTTTDELDGRSVKNLLFGQYEGWRTEF
                     HGEHALGKDSSQYILTDQWKFIWFPVLNHYQLFDMKKDPHEMNDLYPSEKYQPIVRQM
                     KKKLVDFLRYREEGFVVDEELVPVELSKITPTLTKTGDSQS"
     gene            complement(12047..13402)
                     /locus_tag="VQ664_000833"
     CDS             complement(12047..13402)
                     /locus_tag="VQ664_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET2789022.1"
                     /translation="MNTMLDKMQEKLSPIAMKVGNQKFLVALRDSFVGTMPVIMTGSI
                     ALLLNAFLVDLPQQFHLESITKTFQWLVDINNLVFKGSIPIVSLLFIYCLGVNIAKIY
                     KVDTVSAGLVSLASFVISIGSTVTKSFPLANVGDVKLDQILQGIDNLAFDGKNLMVTI
                     GNVIPGNHINARGYFTAMMIGFLASIIFCKVMKKNWVIKLPDSVPPAIAKPFTSIIPG
                     FMAMYIVAILTYVFHLLSNDLLIDWVYKVLQTPLLGLSQSFFAVILMIFLNKLFWFFG
                     LHGGNVLAPIMEGLFGVAMLANLDAFQKGEPIPYIWTSGSFGAFVWFGGLGLVLAILI
                     FSRNSHYRKVAKLGLAPVLFNIGEPVNYGLPVVLNPLLFIPFVLSPVFMATVAYWATS
                     WGLVSPVTQNVTWVMPPILYGFFSTAFDWRAIILSVVCLIISVLTYFPFVKMADKTEL
                     S"
     gene            complement(13412..13729)
                     /locus_tag="VQ664_000834"
     CDS             complement(13412..13729)
                     /locus_tag="VQ664_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET2789023.1"
                     /translation="MDESNLESVMGLIMYGGEAKSNAMEAIQAAKKGDFSKANRRLAD
                     ANAALLQAHKAQTEMLTREAQGEETSISLLMVHAQDHLMTSLTFVDLAKEVVEVYERF
                     EKN"
     gene            complement(13746..14063)
                     /locus_tag="VQ664_000835"
     CDS             complement(13746..14063)
                     /locus_tag="VQ664_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET2789024.1"
                     /translation="MAKVTIMLACAAGMSTSLLVTKMQKAAEDKGLDAEIFAVPAPEA
                     EEIVATKEVNVLLLGPQVRYLLGDFQEKLKDRQIPVAVIPMTDYGMMNGSKVLDLAES
                     LLD"
     gene            complement(14076..15761)
                     /locus_tag="VQ664_000836"
     CDS             complement(14076..15761)
                     /locus_tag="VQ664_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000791288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 16 glycosylhydrolase"
                     /protein_id="HET2789025.1"
                     /translation="MKNKKLISSLFILFLLIFIHVKVFANENLIKNSNFEQGELFWNS
                     RNRGIINSNESYSNGHYSGMIPSTAINDNRADGYIGQVIDIEPNEDYLVSAFAKVDIS
                     GAEGYFTARWFDNNKQGEIVQNNIGEAVDQTVNTTEWKKYMFSFNSGKHDKVLIQLVK
                     WSEDDTTKKSNIFIDNVEMYQLSKGNSYKKIWRDDFDGEQLNKKYWGYELGSIRGWEQ
                     QHYVRSDENVFLRSGNLVLRATNRSKEDQYFNPRNNHRKVVYNSGSVRTHGKVEFLYG
                     KLEMRAKLPKGQGVFPAFWTLGSDFTLDGKINPVQGRGWPSTGEIDIMELVGERNSNG
                     SGNKTVYQTLHYGQSDNDDGKFAGRGTAFKLSSGNFNDSYHTFSIDWYKDYIVWMVDN
                     HIVRKVYYGSDNIAKKIFNRPQYVQLNLAMGGSWPGVVDNNLSGTEFVVDYVSYSRND
                     LQQHQAEEYYSQSPKINGAKDIVINRGDVPDLLKGITTNSGYELDYSIENEPMFNNFG
                     GNTSVDLLIRNKTEKEKISQMPPGVYNLHYTSRPKHLDYESKVDRKTVTLTIK"
     gene            complement(15766..16662)
                     /locus_tag="VQ664_000837"
     CDS             complement(15766..16662)
                     /locus_tag="VQ664_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HET2789026.1"
                     /translation="MKRLISANPSEILQMNAEELKQSILASEGRVVLSENVVTRETFV
                     GDITNSEIARAFGADMILLNCVDVFEPKIYALDSSGDDVIHRLHQLVACPIGVNLEPI
                     DPSAKMLEETQEIVAGRVASVETLNRIEELGFDFVCLTGNPGTGVSNREIIKAVQTAK
                     ENFSGLIIAGKMHGAGVNEPVAELSVAEQLLEAGADVILVPAVGTVPAFHDQELREVV
                     DLVHSKGGLVLSAIGTSQETSDTDTIKEIALRNKICGVDIQHIGDAGYGGLATVDNIY
                     ALSKAIRGVRHTVSRLARSVNR"
     gene            complement(16665..17927)
                     /locus_tag="VQ664_000838"
     CDS             complement(16665..17927)
                     /locus_tag="VQ664_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET2789027.1"
                     /translation="MEKLLQEKLLPVAARLGNNKALVSIRDGITLTIPLLLIGSLLMV
                     IASFPIPGWEKYLGDIGVADYLWKGVDSSFGLLGLVASFGIAYFMARQYKVDGIPAGI
                     VSLSSFITVTPFITGEAGAGMPTAFMASKGLFVAMILGLINGYIYQWFINHNIQIKMP
                     DGVPPAVSKSFSAIIPGAVTIVGWLIVYATLDKLSLPNLHEIAQGALGGPLGLLGNNV
                     IGLLILIFLNSSFWFVGLHGGNVVNAVMKPLWLANLDANKVAYQTGETLPNIFTSVFM
                     DNFVFIGGGGATIGLVLALGYLAHKKKASKQLKTLAPITVIPGLFNINEPAMFGVPIV
                     LNILLLVPFILAPMFNLLVAWGAMASGLVPLTYTDPSWTMPPVISGLLATGSISGSLL
                     QIVLIVLDVLLYLPFVIAIEKRFKLLED"
     gene            18207..19385
                     /locus_tag="VQ664_000839"
     CDS             18207..19385
                     /locus_tag="VQ664_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HET2789028.1"
                     /translation="MTLSKKQLQLRAKILETVYTLGPISRIEIATKTGITPATTSSIT
                     NDLIKENILLELGEDEHDTSVGRKKILLDIQAKRFYYIGCELSEKHFTFALGDNLGNI
                     LKEEKEIVTKQLIQEKGNQLINQTLKQFLNNCSDYEIEAIGIALPGRYLDDYKITTNN
                     PLWQHIDLEMIQSHFDKPLFFSNNVNCMAIGKRLFSRQQNDPNFAYFHFARGMHCSYI
                     YDGNIYGKGNLMIGEIGHTVVSSEGEECSCGRKGCLQTFAGESWLIKKSKILYHQSPY
                     SLLPSLVKNADDIDIQVILTAYQLGDTGIITLIHQALLYLSQTILNISMMIDSQKIYL
                     HSPLLTNQHIIQKLYSEMNYKPKLLYNRLPEVIIEPYNDFTAAHSAIALCLYHTILHS
                     "
     gene            complement(19613..20059)
                     /locus_tag="VQ664_000840"
     CDS             complement(19613..20059)
                     /locus_tag="VQ664_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2789029.1"
                     /translation="MTIRFEEKVSIENAQFVCQWSNSLGKSFQEQWMGPRIPFLLPLQ
                     ALEGVFSIFDEQEFVGLIQKIRLEDSNLHIGRFFINPQKQEQDLGSQALRKFVSLAFE
                     NEDIDSISLNVFEANQRAQNLYQKEGFEIVQMVEAPVRKYSGLKLE"
     gene            20129..20788
                     /locus_tag="VQ664_000841"
     CDS             20129..20788
                     /locus_tag="VQ664_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HET2789030.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTPLR
                     PLDLIPILSQVFNRFRCRYCKVRYPVWYALFELGLGLLFLLYSWELLSLGQVVLITAG
                     LTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
                     FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCVIIFGKLLL
                     V"
     gene            complement(20840..21991)
                     /locus_tag="VQ664_000842"
     CDS             complement(20840..21991)
                     /locus_tag="VQ664_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HET2789031.1"
                     /translation="MFNGRVLKELRLLNGLSRAELAQRINLTEQAIWQFESNETKPKL
                     STKMHLANQFHVDLTYFEQEEESIRFDSSVIAFRNADLATRKTIDIQTMYLHKVDSLI
                     DYFESFVIIPNITIHDLSNVVSESYHKGESIEELALYAREKLGISKDNHDLLYKLERS
                     GIYIVERLINGQADAYSAWSKLGRPYIVLGTNKSSVRRNFDLAHELGHILLHKYKDMN
                     EDGDRLEQEANYFASCFLLPKEEFLVKFEERVGKRVSNPDSYILLKSDLNVSIQALEY
                     RAFKLGLLTPKQHSYFYRQIAQKGYKMIEPLDDQIFVKKPSKVKSILDVVLSNHLVSL
                     ATIMSKQSIRLQFISEIFSVEMKFFDQYQEDRRTDRFDNIIPLYKRNNL"
     gene            complement(22006..22737)
                     /locus_tag="VQ664_000843"
     CDS             complement(22006..22737)
                     /locus_tag="VQ664_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000934015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789032.1"
                     /translation="MLNQDLFDSLEAQKIVDTLMKGQKDYVDERLEKRETMIVSNGYA
                     WTRPNHIDTAFASADLFEYKLQLAGQTWGYLEFETNTEKYGKVLLIIKGKKRLTNQFP
                     LVQKNKSGYLFEYAQMNTLYLNQHSSYKNDEDSHSFPIQMELVSDEMIQEIEQATKNS
                     NIEKFMILTYEADSENNIISVDVVMPDARTGQLHLIQDLSEYIQSSSYHFEEAKYQDI
                     PNFSELSETEDFEIIPRIEKQEGQK"
     gene            22966..23067
                     /locus_tag="VQ664_000844"
                     /pseudo
     CDS             22966..23067
                     /locus_tag="VQ664_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234126.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
     gene            complement(23039..23815)
                     /locus_tag="VQ664_000845"
     CDS             complement(23039..23815)
                     /locus_tag="VQ664_000845"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HET2789033.1"
                     /translation="MPKTLTKKLNAIKAAGKGIFVPYIMAGDHEKGLDGLAETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDIALIPLVSLTTGI
                     ERQKELIEGAEGFVYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIKQAVAYQK"
     gene            complement(23808..25031)
                     /gene="trpB"
                     /locus_tag="VQ664_000846"
     CDS             complement(23808..25031)
                     /gene="trpB"
                     /locus_tag="VQ664_000846"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HET2789034.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDLTGQNLPDALVACVGGGSNAIGLFHPFVEDESVAMYGAEAAGFGVDTEHHAATL
                     TKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            complement(25009..25608)
                     /locus_tag="VQ664_000847"
     CDS             complement(25009..25608)
                     /locus_tag="VQ664_000847"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HET2789035.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEAAE
                     LAKLIPADVKKVGVFVSPSRVELLEAIDKVGLDLVQVHGQVAADLFENLPCASIQAVQ
                     VDGNGHVPNSQADYLLFDAPVAGSGQSFDWGQLDTTGLAQPFFIAGGLNEDNVVKAIQ
                     HFTPYAVDVSSGVETDGQKDHEKIRRFIERVKHGISGTK"
     gene            complement(25595..26362)
                     /gene="trpC"
                     /locus_tag="VQ664_000848"
     CDS             complement(25595..26362)
                     /gene="trpC"
                     /locus_tag="VQ664_000848"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HET2789036.1"
                     /translation="MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLAEFLKNHQDC
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNTGATVILLIVAALSEERLKELYDYATELGLEVLV
                     ETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAENVAQRIKELQIDKG"
     gene            complement(26359..27363)
                     /gene="trpD"
                     /locus_tag="VQ664_000849"
     CDS             complement(26359..27363)
                     /gene="trpD"
                     /locus_tag="VQ664_000849"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HET2789037.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALK
                     MKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEDYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            complement(27374..27940)
                     /locus_tag="VQ664_000850"
     CDS             complement(27374..27940)
                     /locus_tag="VQ664_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HET2789038.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMICDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEDGRAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEKVVK"
     gene            complement(27937..29298)
                     /gene="trpE"
                     /locus_tag="VQ664_000851"
     CDS             complement(27937..29298)
                     /gene="trpE"
                     /locus_tag="VQ664_000851"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HET2789039.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFSILAY
                     NPVFEIKFENGVLYQNGQAIDRDPLDFLYEVTHKSQHHSDLPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYMVFDHKKEKIHVIEDALYSERSQEALEKSLNQV
                     LEELRIPAPNEFEDLDLSPLDFKPHIAPHKFEGMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLRVTNPSNYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGATDEEDKALATDLLSDEKETAEHRMLVDLGRNDIGRISETASVQVTKYMEVELFRY
                     VMHLTSVVKGRLLAELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRSVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
     gene            complement(29799..29876)
                     /locus_tag="VQ664_000852"
                     /pseudo
     CDS             complement(29799..29876)
                     /locus_tag="VQ664_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(30481..31482)
                     /locus_tag="VQ664_000853"
     CDS             complement(30481..31482)
                     /locus_tag="VQ664_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET2789040.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
     gene            complement(31590..31958)
                     /locus_tag="VQ664_000854"
     CDS             complement(31590..31958)
                     /locus_tag="VQ664_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789041.1"
                     /translation="MKDYKINFDLGKIEYFDNNCLIQVYKFISFYDICEMVFAFHLPP
                     DELITNVIFKEKINSMLKCYIDRLLYVFINPTHFTEKVNLQFYGSFFSYEFICREVGN
                     ILKNKGVKCNLNFFEGEEYL"
     gene            complement(32054..32764)
                     /locus_tag="VQ664_000855"
     CDS             complement(32054..32764)
                     /locus_tag="VQ664_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HET2789042.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
     gene            complement(32767..34458)
                     /locus_tag="VQ664_000856"
     CDS             complement(32767..34458)
                     /locus_tag="VQ664_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HET2789043.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDPNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            complement(34470..35480)
                     /locus_tag="VQ664_000857"
     CDS             complement(34470..35480)
                     /locus_tag="VQ664_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2789044.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            complement(35583..36650)
                     /locus_tag="VQ664_000858"
     CDS             complement(35583..36650)
                     /locus_tag="VQ664_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET2789045.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDVKEMPKDWT
                     ELGSKYKGKYSIYGLQGGTGRAILASILVRYLDEKGDLGVSEKGWEVAKEYFANAYTL
                     QKGESSVVKALDKESPIQYGMIWGSGALIGQKEQNVEFKVMTPEIGVPFVTEQTMVLS
                     TSKKQALAKEFIDWFGQSEIQVEYSKKFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVK"
     gene            complement(36675..37334)
                     /locus_tag="VQ664_000859"
     CDS             complement(36675..37334)
                     /locus_tag="VQ664_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HET2789046.1"
                     /translation="MKNLTKIKFKENGEFNHFPGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIHMRITEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVCFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
BASE COUNT        12046 a         7633 c         5729 g        12043 t
ORIGIN      
        1 gtacaccata gtaattgttg agtttaatgg gccaccttgc gtcataacca ttggttgtac
       61 aatcagctta aaagcagaaa ttaaagttgt taacaataca aacagggctg ttggttttag
      121 taggggcatc gtgatataac gaaactgagc ccattttgag aatccatcta attcagcagc
      181 ttcatagaca tcttgtggaa tattctgcat tcctcctaaa aataaaagca tctgataacc
      241 tgcaccctgc caagcagaaa caaaaacaat tgcatacata gcttgtttag gactagtcaa
      301 gaaaggttga gaagcaatac ctaccttatt taaaatagca tttaataagc cactatttgg
      361 atttaaaaga taaagccaaa gaatagaaat aactaccaag gacatgacaa ctggagcaaa
      421 aaaagccact ttaaaaaaca tatttccttt tcgcttttta ttgacaatca aagccattcc
      481 taaggccgct cccaattgaa ctggaataat ccaaacaaca aatttcaaag tattcaagaa
      541 gctctttaag aaaatcggat cttttgttaa tcgaataaaa ttttcaagtc caacaaattt
      601 tctttcatct ggtgtcaaca aataataatc tgtaaaagcg taataaatga ccattccaac
      661 tggaattact aaaaagatac ctaataaaat taaagctgga gctaaaaaac tataacctaa
      721 tatgttatcc tttatttttt cacgtctttt tgtatacaca acagtttctt tactcatatc
      781 catctccttt aatcatatat atcaaactag gctattaaca agaaagggga aggtagttcc
      841 aaacattttc cttccacctt cttttttaca gattatttga gtgactgatc aatagcagtt
      901 tgcatttctt ttgtacgagt atccaagact ttttgcacat ttggattttc ttcataatag
      961 ctaatatctt gcattgcttg ttgaaaagct cgagaaacct gaggatatgc tacgacaact
     1021 gggcgagcat gagctgtttt tgaattttgt tccatcaaga aacgcattgg ttcggatact
     1081 ttatctttga tattttcaat tgtagattta cgaattggaa ggaccgaatt ccccaagcta
     1141 ataatttcac ttgattctgt atttgtagca aatttaacaa attcagatgc ggcctctttt
     1201 ttatcagatt ttgtcgtcac agctaattgc caactacctg aaggggatac taattttttc
     1261 gtcttactag atactgggta aggaaggata ccaaaatcaa tatctttgta gtttgtattc
     1321 atgtcagcaa tcgtccaaga accactcaaa agcattggat actctcctgt ttcaaaacct
     1381 ttttcgactg gactaacagt tgtatagcct tcttttacaa gattttgaat gaattgaact
     1441 gcttctacac tctctttgga gttgaagtat ccttctgcct ttgttccatc ttcgtttacg
     1501 acagaaccat tatttgacca aatcaacggc atataagcat atggcaacat ttcatcgttt
     1561 gaattaatac gaaaatcaat tgctggtttg ttataatgat ctttcaattt tttagcaatc
     1621 gtattaaatt cgtcccatgt ccatggcttt tctagcgttg gaagctctga ttccgcaatt
     1681 ccagcctctt tgaacatttt tttattgtaa taaacaccaa cattcgattc agaaaatcca
     1741 aatgcataga atttcccatt ataagttccc tgttgtttaa tactgtccaa aacatcatcc
     1801 atattattat cttttagata atcatctagc ggagtaatta ctttagattt tgcataagct
     1861 gccgtatttg gtccatcaag ggtaataaca tctggaagac tattagtcgt aatagcagca
     1921 ttaaccttgt cttcatatcc tccaccacta ccactacgag gaatatactc agttacaacc
     1981 ttgtacttac tttttcctga ttgattaaag ttatcaacaa ctttttgcca agcttttcct
     2041 tcatttgttt cgtcagagaa ttgtacccag actttaatat catttgaaga actcgcttgt
     2101 tttgagttag ttcctccact acaacctgca agtatagcta acgatagccc cgcaacaaca
     2161 gataacattg tacctttacg catcattttt ctcctttttg aaacgtttca ttttttattt
     2221 attttttaaa caagcttcta gcctattttt gaaacgtttc atttgttgat tatattataa
     2281 cagcgctttc attaattgtc aagcgctttt taaatttttt ttgttgtttt atctccccca
     2341 aaatatgtgg gaattacgat tcgtttttct agaatctctt ctcgcttaat cattttcagt
     2401 atcattgcaa cagattcttt tgccatcata ccaatatctt gaactattgt agacactaga
     2461 taagattgat cgacagaagt ttttaaacca tcaaacccaa ttatctggta atcatcaggt
     2521 gctattttcc ccagttcttt cataacacta ataactctca gagccatcat atcatttatt
     2581 gtaaatatac catcaatttc tttatgagat tgcaaaaaaa ttcttatctg atcttcagga
     2641 tttattaaag gttctttcat ttcaaaatta tagacatcta ctcctaattc cttagctttt
     2701 tctctgaatc ctttacttct gagtatagtc tcattctcat acatattaat tgaaccaata
     2761 aaagcaaggt gcttattatc ccttctaacc agttcctctg ctgcagtttg tcctcctttg
     2821 taatttgctg aagtaacata gcatacattt tccgaaaaat gtctatctat acttacaaac
     2881 ggtaaatcag ataaaatata tttgtcaata tcagaatatg taataccaat aattccatcc
     2941 actttatttt gtttcaacat ttcgatatat tcgatttcat tttgtgaatc gctatcagcg
     3001 ttacaaataa ataatttata attatatttt aataactctt tctcaacatg ataggcaaac
     3061 tccgaaaaaa atggatgcca tatgctcgga ataatcaaag cgatagtttc tgttctattc
     3121 tttttcatac ctcgagcata attatcaggg atatagtcca atgtttttat agccctttga
     3181 actttcctta aagttacttc tttaatgcct ttttctttat taattacacg tgaaacagtt
     3241 ccaacactaa ctcctgcttc taaagcaaca tctttcatgg taattgattt tctttgttct
     3301 accatattat cacctccttt caatatatag tatcatgcaa atgcttttta agcaactatt
     3361 tctcaatcat ttttggccag atcatttatc ccatcatgaa taaaatcact ccaattagct
     3421 tttgaaaata cttcaatttt catgtgtaaa catctacata aaacaggaaa agccttggtt
     3481 ttatggcttt tttcgtatct tctacaaaaa aagcaagagt tttagagggc tataaatcta
     3541 gatgtacatt ttgcttaaat gattgaaggt cttttcttaa caaaaacacc ccaaaaatta
     3601 gattttttct gtctaacttt tgaggtacag ttcaaacgcg aaatagcgtt tttttgttat
     3661 ttttggttac tcatctaatc gaataaacat catggcattt aacaaatata tgagtgagac
     3721 cgtgtttata ttatttgaat agatgagtct cttattttca ataggaggaa taataaaatt
     3781 agaaataatg atatcataag atgaatcttc taaagattcc tttgataatt ctaattcagt
     3841 ccaaacttcc agttcaaaat tattgctaca gtaataagaa agtgtctctg caacgaattt
     3901 tgcatgatac tgatcaaaat tactcataac caaaaccttt agtttaggct gattttgtag
     3961 caaattaatc accaaatgtt tggtatgagt gatgaaggta taagatagat gatttaccat
     4021 cattgaacta gaacaaacct caagagtctc taaatagtga gaaagctctt tttttatatc
     4081 tgaaacaaat tttggaaaaa tattttgaaa gttcctgatt gtattccctt tttgatcaaa
     4141 taaaataaac tcagtaaaca actcttgacg atacagatgt gcggtattat gcagatgcca
     4201 aatcagatta tccttattct ccatttcaat ctgatacttg actgaaatct gatcaataaa
     4261 atcactcaat agatggtaag atttttcaac ataactatcc ttttttacgc atttcataaa
     4321 gagactttca tctatgaaaa acattttttg aaagtaagac acaaataatt ggcaaacaac
     4381 ttcttcatct aaagagatat tgtattctga ttcaaaactc tgagcaacac cttctattcc
     4441 ttctgcctgc attaaaaaat ccaaactttg gtcgttaaaa gaatctttat ctacttccat
     4501 aaaatgacca aactttattc tatataggtt cgtaactagg agcaacttta gcattctatg
     4561 cgttgacaaa ttcattggaa agcttgtttc cttataaacc aattctaaca attgagatag
     4621 tggctctgat gaaaaatttt caaatggcca ttctaggaaa taatattttt ctgaaaaata
     4681 ttgtgcaaaa aagtaacgaa tgtctctctc atttccaatg atttgaacag gggtcagact
     4741 gacttcaaat tgaaattgcc ttttaatcac tttattgatt tggctaataa tacgatagag
     4801 cgaagatgaa ctgatataaa attctttaca aatactctca gcttgacaac cttcattaaa
     4861 gaagatgaat tctaaaatcg aaaaatgagt tgaatgttta aagaaatgat ggtaaaccat
     4921 ttcaatatca ctatcatcgg tattaataat gcgtatacca ttagtagaag aatgaaaaat
     4981 caagtcagga aaagcagatt taacatggga tagatcatct ttgactgcac gttctgtaca
     5041 atttaataac tctgctagtt cagaacgatg aaaccaacgt ttatgttcaa ataataattc
     5101 taataattct aattgcctat gacttttttt agataataaa tctctcatga atatctttct
     5161 ctctttataa attatcggat taaacctctt gcaattatac cacaaagaat aggtatagca
     5221 tgatataacg acttttccta aaatctttta tttcgtataa taacactacg gagacaatat
     5281 ataaacaatt ttcttatttt accgtctatt gagggcgtga atacagaatc aaattcaagt
     5341 ctaaagatta tatttttaat tttaaaaatt atataatagc aacaattaaa gaatttgatt
     5401 ttttaaaatt atataataat aacaatcgaa ataattgact tttctatatt aaagttatat
     5461 aatagtatta atcaaagaaa ttgatttttt gatattaaaa taaaaaagga gggtaggcag
     5521 tgttgtgatc aattattgct ggaggtctta ttggtctctt ggcaggtaaa atcactaaaa
     5581 aagtagttct atgggaatca tcgcaaatgt attcgctggt ttagtcgggg catatgcagg
     5641 acaatctctt ttaggtagtt ggggtccatc aatcgctgga atggctttgc tcccatctat
     5701 tgtaggtgca gcgattgtga ttactgtagt gtcattcttt acaggtagaa agtaaacttt
     5761 tcgccagtaa agttagcaaa ctatttttaa atcaatgacg ggaaaaatag tttaaatgtt
     5821 aaatcgaaag gattgtatat gtcaaaagca aagaaaatat gtttcattat tttctgtatt
     5881 ttaatcttga caattttcct tcctgttttg atagattatc atcaagttag tgatctaggt
     5941 attcatctac ttagctggag acagaactcc gtagttgaat tctatcttgc tagatatgtc
     6001 ttttggggga cagtggttct atcaacttta gttttattat ccattttagt tgtgatgttt
     6061 tatcctaaac gttacttgga aatccaactt gaaactaaaa acgatacatt aaaattaaag
     6121 aattcggcaa tcgaaggttt tgttagaagt ttggtgagtg atcatagatt gatcaagaac
     6181 ccaactgttc atgtaaattt acgaaaaaat aaatgtttcg ttcatgtaga aggtaaaatt
     6241 cttccttcag acaacatcgc tgacagatgc caaataattc aaaatgaaat aactaatgga
     6301 ttgaagcagt tttttggtat tgagcgtcaa gtaaaacttg aagttgcagt aaaaaattac
     6361 caaccaaaac ctcaaaacaa aaagactgtt agtcgtgtga agtaaggaag taaaaaatgg
     6421 aatggcttaa acaatatcga tatccaatta tcgctggtct cataggcgta tttctggctt
     6481 gtttgattgt ctcctttggc ttcttcaaaa caatatttgt attgatttta ggagcactgg
     6541 gagttgcagc tggattatat atcgaaaaaa actatataga taaataaaaa aataaaaatt
     6601 actaatttaa ttaaaggagt ttcatatgtc aaacgaaaaa aacacaaata ctaacgtaga
     6661 aaagaaagat gctactgttg tagctcacga aatcaaaggg gaacttactt acgaagataa
     6721 agttatccaa aaaatcattg gtctttcact agaaaacgtt tcaggtcttt tgggaatcga
     6781 tggtggtttc ttctcaaatc ttaaagaaaa aatcgttaac agcgatgacg taacaagtgg
     6841 tgttaacgta gaagttggta aaacacaagt tgcagttgac ttaaacgtta ttgttgagta
     6901 ccaaaaaaat gttccagctt tatattcaga aatcagagaa atcgtatctt cagaagttgc
     6961 taaaatgact gacttggaaa ttgttgaaat caacgtaaac gttgtcgaca tcaaaactaa
     7021 agaacagcat gaagcagact cagtaagcct tcaagatcgc gtatctgacg ttgctgaatc
     7081 aacaggagaa ttcacttcag aacaattcga aaaagctaaa tctggtcttg gatctggttt
     7141 ctcaactgtt caagaaaaag ttagcgaagg tgtagaagct gttaaaggtg cagcaaatgg
     7201 tgtagtatct cacgaaaaca ctcgtgtaaa ctaagataaa ataaatataa caggagaaat
     7261 tatcatgtca gtagaagaaa aattaaatca agctaaaggt tctattaaag aaggtgttgg
     7321 gaaagccatc ggtgatgaaa aaatggaaaa agaaggagca gctgaaaaag ttgtttctaa
     7381 agtaaaagaa gttgccgaag acgctaaaga cgctgtagaa ggtgctgtag aaggtgttaa
     7441 aaacatgttg agtggcgatg ataaataagg ttaaaagtta ctttatcttt ttggtaacat
     7501 tagtcaaaag agtctgagtc aagatgattc tcagaaaaca aaaagctaga gattcccaat
     7561 tgcggaactc tagcttttta attttgcctc tttctcttat tatatttcag caggttgttg
     7621 gccatgagta tgaatcccat gtcaattctc acttgacgct tacctctcag atgacatctc
     7681 ttataaccca aacaaacctt tatctgccca aagacagatt tcatatcaat cttacgttta
     7741 gcgaaaattt gtctaccctt ggaagataaa agtgcctgat attctttagt ttttaaacac
     7801 tggtaacgtt cattcatata cagtcccttt tgaggggctg attcaggttc ataatcgcag
     7861 tcaacattga tttcaaggct gtttgctttc tatctcccct ttttcatgat atattttcgt
     7921 acaggttctt caatagtttc tatagtaaaa tgaaccaaaa atagtacacg ttgcggtata
     7981 atgttcttgt ggcatattca ttagattttc gtaaacagtt ctctcctatt tgtgagcgaa
     8041 caagtatagt caattgattg tcagtttgaa gaccaagagt cgtaaggcaa aggatatggc
     8101 agaatccatc caagggtggc tggcacaatt tctagtgaac ctctttaaat ctattacgtt
     8161 tgactgtgga aaagagtttt caaaatggaa agatatttcc aatcatcacg atagtgagag
     8221 cttttttgcg aatctaggat gttcaagaca gcggcgtctc aacgaacatt caaatagact
     8281 tttaaggtgt catgacttgc caaagcagac agatttcaac gaagtcagtc aagaatttta
     8341 ggctggacaa aaactcaatt tcaggagaaa atgaaataaa tattcccaca ataaaacgca
     8401 tagtatcaaa gtttttccaa cacctgatat tatgcatttt ttaattttaa agactttttc
     8461 ccagcctcaa gaaatcacat cccacctaaa tcctttggat accaaatacc tcatcaggta
     8521 ttttctgagt tggtaagaat gtctagctta atttgacaaa tggagggcgt taaatccagt
     8581 ttttacagga agtctattta aatattttca cactgacctt acaaaatatg aaataaatta
     8641 tataaagtca ttcccatgac aaagaataac atccctttaa aacagtatct tacccaattt
     8701 tcaggtaaga cttttgatac aaccgtcccc aatacccctc cgcatataga agcaagaaaa
     8761 ataactggaa caggtgctaa atgatactga tttaaacctg taaccacaac aattgtagcc
     8821 aaatgagaca gctgggaaaa gaaaataatt gcaagagaat acatcgttgc ttcttttatc
     8881 gaaatagaaa aaaacaccat caataaagat acattgagcg gaccaccacc aatccctaaa
     8941 aaactagaaa ttaagcccaa tagaagacca caaatcatat agaatcctat cttatcaaat
     9001 tgataagttt ttttaaaatc tgttaaaaca aatgatacaa gtagcatcac aaatagtaaa
     9061 atcatttgaa caatggatac tagccgtact gataactgag ataacaaaac ttgaaaaata
     9121 agatgaccta gaaatcctcc taaaacagaa gaaaaggata ccgtaaaaat caatctccat
     9181 tttatctctt tactttgtga aaatcttttg attgttgaaa taatcgccat tataaaaaca
     9241 gagaaactag aataaaaagc aatatcactg accgaatggt atccaaaact atccataagt
     9301 ggcttaatta taattccacc acccatgcct gatatagaac ccaatccact agctattata
     9361 atgattagaa aataaataat ctcaaccact ttttaagtcc atcctattct ttcaaacatc
     9421 taaaacctag atggctacta gtggaagtag agatacatcc atttctagca gctactcggt
     9481 atcgattaca ataagaacaa tgacataaaa aggaacctcc tctgatagca tactcctcat
     9541 cttgtatccc atattttggc aactcatagt catcttcatt aaaactagct aataaggtat
     9601 atctcggatt gcgacaccat tcccaaacat tcccaatcat ttgatataga ccaaaatcat
     9661 taggtaaaaa ttcatagaca ggagccgttc ctataaatct atctaaggca gtattttcat
     9721 aaggaaatct tccttgccaa gtattggcat gataatatcc accttctaaa agagtatctc
     9781 cccaaggata ttcagattgt cttcctcctc tagcagcata ttcccactgt gcttcagtag
     9841 gtaaagacat tccgctccaa ttacagaaag ccaatgcatc ttctaaagca acatgaacta
     9901 ctggatggtc ttctaaaccc actagattac tgttctcacc gtagggatgt ttccagcaag
     9961 cgttcggaac ttgtaaccac cacggagccc cagcaggatg aggatatccc tccctttctg
    10021 cctctggaac gaacaatata aaaacaaaag accactcttg tcgctcagct agtgttttat
    10081 agcctgtttc tttcacaaat tgagcaaatt cttgattcgt aactggagta tccgcaatgg
    10141 aaaaatcctt tacactaaca gcgacttgag gaccttcaaa atcatctaaa aagccctctt
    10201 cagaatttgt tcccatcata aatgtcccac ccttgatttt tttcattttc atgattgact
    10261 atcccccgtt ttcgttagag ttggcgttat tttagaaagt tcaacaggaa ctaactcttc
    10321 atccacaaca aaaccttctt ctctatatct aagaaagtct actaattttt tcttcatctg
    10381 acgaacaata ggttggtatt tttcgcttgg atacaaatca ttcatttcat gcggatcttt
    10441 tttcatatca aataactgat aatgatttaa aacaggaaac cagataaatt tccactggtc
    10501 tgtcaagata tattgactag aatcttttcc taaagcatgt tcaccatgaa attctgttcg
    10561 ccacccctcg tactgtccaa ataataaatt cttaacactc cgtccatcta gttcatctgt
    10621 agtagttcct cctgccaaat ccacgagtga aggaaaaata tcttgaattt tcactaattg
    10681 cttgattgtt cccctattac cagctatcaa tccagccgga tcgtaaataa acgaaggaat
    10741 gtggatactt ccctgataag gatatccctt tctaaacaga taatgttcac caagctgatc
    10801 tccatgatcc gaaacaaacc agataatcgt atctttatca tgacgaaatt cttttaggga
    10861 agtcaaaaag cgactaattt gatggtctat atgagtaatc aatccaaaat aagcagcaac
    10921 cattcttctt tgatcatctt cctttaattt ccctcttaaa gcataaatag acggaatttg
    10981 cttttctaat acttcccaat tcccgatatg caaatcgaga aattgaggca agcgttccat
    11041 atacatatca aaatagtatt ttgggggatt taatggagca tgtggttttt caaaagacat
    11101 tttgagaaaa aaaggaaccg ttggatctct tctttgtaaa aatgaaatgg actcactcac
    11161 aacccagttt gttggatgta acttctcatc tttatcccaa ggtctagctt cccaagaatt
    11221 acaatccatt ccgtcatcaa tcaaatcaac atcataacca actttaccct ttaaaaaggc
    11281 tagatagtca ctaacataat caaattgact tccataagcc ttatcatact ttctatcaac
    11341 atgtagatac ccatcgtgaa gtaagacatg atcaaaccca agtctctgtc tggaaggaaa
    11401 aacatgcatc ttaccaatac actctgtttg ataacccata tctttaaaga cttttggaag
    11461 agtattagta aaattccaag gcacctcatc ttgataacca acacgtccac ttttatcttg
    11521 gtctaagcca gtcaataaag ctgccctagc aggaacgcaa gaaggaactg gagaataggc
    11581 attttcaaaa ttataaccta cactagccat catatctaat gttggagtgc taactagctt
    11641 atccttacta ttcaaggata aggcgtctgc tctcatttga tctacaacaa tcaaaataat
    11701 atttggctgt tttgtctgaa ccataaaatc tcctttctaa tatggcaaaa gaggcacaag
    11761 aagatatcta cctttactgc acccctttct atatcaatct ctctatataa agcaataaca
    11821 ttcttgttat gttttataga acaatgaact aaaatatgac taaatcgatt aggaaattca
    11881 aatcattttc tagtactgtt ttagaagtta cagtgtacta ttccaacttc aacaaactat
    11941 aaaccttggt ctaataacaa ttttagtgga gataagaaat cctacaccta actcatctta
    12001 cacgtaatct atttctattt tatcacaaaa aacgcaagta agaccattaa ctcaattcag
    12061 ttttatctgc cattttcaca aatgggaaat aagtcaagac actaataatc aaacaaacaa
    12121 ctgataagat gatggcacgc caatcaaatg ctgtagagaa gaaaccatat aaaattggag
    12181 gcattaccca agtaacattt tgtgtaacag gtgaaacaag accccagctt gttgcccagt
    12241 aagctaccgt tgccatgaaa accgggctaa gtacaaatgg tataaatagc aaaggattca
    12301 agacaactgg taaaccataa ttgaccggct caccaatatt aaacagaact ggtgctagac
    12361 caagtttagc aacttttcga taatgactgt ttcttgaaaa aattaaaata gcaagtacca
    12421 atcctaatcc tccaaaccag acaaacgccc caaaagaccc acttgtccat atataaggaa
    12481 tcggttcacc tttttggaaa gcatccagat tcgctaacat agcaactcca aacagccctt
    12541 ccatgatggg agccaataca tttcctccat ggagaccaaa aaaccagaat aacttattta
    12601 aaaagatcat cagaataact gcaaagaaac tttgagacaa acctagtaat ggcgtttgta
    12661 acaccttgta aacccaatca atcaataagt cattgctaag taaatggaaa acataagtca
    12721 agatggctac tatatacatc gccataaatc ctggaatgat agaagtgaac ggcttagcaa
    12781 tcgcaggggg aactgaatct ggtaacttga ttacccagtt ctttttcatt actttacaga
    12841 aaataataga ggctaaaaat ccaatcatca tggctgtaaa gtagcctctg gcattaatat
    12901 ggtttcctgg aatcacattc ccaatagtta ccatcagatt tttaccatca aatgctagat
    12961 tatcaattcc ttgtaagatc tgatctaatt tcacatctcc tacatttgcc aaagggaaac
    13021 tctttgtaac tgtacttcca atcgaaatga caaacgaagc aagtgatacc aaaccagcag
    13081 aaactgtatc aaccttgtaa atcttagcga tattcactcc caagcaatag atgaacaaca
    13141 aagaaacaat tggtatactt cccttgaata ccaaattatt gatgtcaaca agccactgaa
    13201 aggttttcgt aatactttct aggtgaaatt gttgtggtaa atccactaga aaagcattta
    13261 ataacaaagc aatggaacct gtcataataa caggcatagt ccccacaaat gaatcacgta
    13321 aagcaactaa aaacttctga ttcccaactt tcattgcaat tggagaaagt ttttcttgca
    13381 ttttatccaa cattgtattc atactaaact cctaattttt ttcaaatcgt tcgtatactt
    13441 ctaccacttc tttcgccaag tcaacaaaag tcagactcgt cattaaatga tcttgcgcgt
    13501 gtaccatcaa gaggctaatt gatgtttctt ccccctgtgc ctctcttgtc aacatttctg
    13561 tttgagcctt atgcgcctgt aataaggcag cattcgcatc agctaatctt cgattggctt
    13621 tagagaaatc cccttttttt gctgcctgaa tagcctccat agcattactt ttggcttccc
    13681 caccatacat aattagcccc attacagatt ctaaattact ttcatccata acattctcct
    13741 caatcttagt ctaataaact ttcagctaaa tctaaaactt tagaaccatt catcattccg
    13801 taatctgtca tcggaataac cgccacagga atctgtctat cttttagttt ttcttgaaag
    13861 tcccctagta aatagcgaac ttgggggcct aaaagcaaca catttacttc ttttgttgct
    13921 acaatttctt ctgcttcagg agctggaact gcaaaaattt ctgcatccaa ccccttatct
    13981 tctgctgcct tttgcatctt tgtcactagc agacttgtac tcatacctgc tgcacacgct
    14041 aacataattg ttactttagc catagcttac tccttttatt ttattgtcaa tgttactgtt
    14101 tttcgatcaa ctttagactc ataatctaaa tgtttgggac gactagtata atgcaaatta
    14161 taaactcctg gaggcatttg tgaaatcttt tctttttcag ttttattgcg aattaataaa
    14221 tctaccgaag tattccctcc aaagttatta aacataggtt cattttcaat agaataatct
    14281 aactcatatc cactattagt tgtaattcct tttaataaat caggaacatc tcctctgttt
    14341 attactatat ccttagcgcc atttattttg ggagattgac tataatactc ttcagcttga
    14401 tgttgttgta aatcatttct agagtaagaa acataatcaa ctacaaattc agtccctgat
    14461 aaattattgt ccactacccc aggccaactt cctcccatcg ctaaatttaa ctgaacatac
    14521 tgaggtctat taaaaatctt tttcgctata ttatctgatc cataatatac ttttctaaca
    14581 atatgattgt caaccatcca tacaatataa tctttatacc aatcaattga aaaagtatga
    14641 tacgaatcat taaagtttcc actcgataat ttaaaggctg taccacgtcc tgcaaatttt
    14701 ccatcatcat tatccgactg tccataatga agcgtttgat aaactgtctt attcccactt
    14761 ccatttgaat ttcgttcacc aactaattcc attatatcta tctcacctgt tgacggccat
    14821 cctcgtccct gaacaggatt aatcttccca tcaagtgtaa aatccgatcc aagagtccag
    14881 aaagcaggaa aaactccttg acctttcggt aattttgcac gcatctctaa tttaccataa
    14941 agaaattcta ctttcccatg tgttctaaca cttcctgaat tatatacaac ctttctgtga
    15001 ttgtttcttg ggttaaaata ctgatcttcc ttagagcgat tcgtagctct aagaactaaa
    15061 tttcccgaac gtagaaaaac attctcatca cttcttacat aatgttgctg ttcccaacca
    15121 cgaattgatc ctaattcata tccccaatat tttttattta attgttcgcc atcaaaatca
    15181 tctctccaaa ttttcttata tgaatttcct ttagacagtt gatacatctc tacattatca
    15241 ataaaaatat tagatttttt tgtagtatcg tcttctgacc atttcactaa ttgaatcaaa
    15301 actttatcgt gtttaccgga attgaaagaa aacatgtatt ttttccattc ggttgtatta
    15361 actgtttgat caacagcttc tccaatgtta ttttgaacaa tctctccttg cttattatta
    15421 tcaaaccatc ttgcggtaaa atatccctct gctccactaa tatctacttt ggcaaaagca
    15481 gatactaaat aatcttcatt aggttctata tcaataactt gtccaatata tccatctgct
    15541 ctattatcat taattgcagt agaaggaatc atacctgagt aatgtccgtt actataactc
    15601 tcatttgaat taattattcc cctatttcta gagttccaaa acagctctcc ttgctcaaaa
    15661 tttgaatttt ttattaaatt ttcattagca aaaactttca catgaataaa tattaataaa
    15721 aataatataa ataaacttga aattaatttc ttattcttca ttttatcacc tatttactga
    15781 cctagccaag cgagatactg tatgtctcac tcctctaatt gccttgctca atgcataaat
    15841 attatcgact gttgccagtc ccccatatcc tgcgtcacct atatgttgaa tatcaactcc
    15901 acaaatttta tttctaagtg caatttcctt gatagtatct gtatcagatg tttcttggct
    15961 agtaccaata gcactcagta ctagcccacc cttactatga acgagatcaa cgacttcacg
    16021 caactcttgg tcatgaaagg ctggaacggt tccaactgct ggaacaagta tcacatccgc
    16081 acctgcttcc aacaattgct ctgcgacaga aagctctgcc acaggctcat tcactcctgc
    16141 cccgtgcatc ttacctgcaa taatcaaacc agaaaagttt tccttagcag tttgaacagc
    16201 cttaatgatt tctcgattgc taactcctgt tccaggattt ccagtcaaac agacaaagtc
    16261 aaaacctaac tcctctattc gattcaatgt ttcaacacta gcaacacgac ctgcaacaat
    16321 ttcctgtgtt tcctctagca tctttgcaga tgggtcaatc ggttccaaat ttacaccaat
    16381 tggacaagca acaagctggt gtaagcgatg aataacatca tcacctgaac tatccaaagc
    16441 ataaatttta ggctcaaaaa catcaacaca attcaataaa atcatatcag ctccaaaagc
    16501 tctagcaatt tcagaattag ttatatcccc aacaaatgtc tcacgagtaa ctacattttc
    16561 agatagaaca actctacctt cacttgctaa aatactttgt tttaattctt cagcattcat
    16621 ctgtaatatc tcagatggat ttgcactaat taaacgtttc attctcaatc ctccaataac
    16681 ttaaaccgtt tttcaatagc tattacaaat ggtaaataaa gtaagacatc caaaacaatc
    16741 aatacaattt gtaataatga accagaaata cttcctgtag caagtaaacc acttataaca
    16801 ggtggcatag tccaacttgg atctgtataa gttagcggaa ccaaacctga tgccattgct
    16861 ccccacgcta ctagtaagtt aaacattgga gctaagataa atggaactag taacaaaatg
    16921 ttcaaaacaa taggaacgcc aaacattgct ggttcattta tattaaataa tccaggtata
    16981 acagttatag gtgccaaagt ttttagttgt ttactagctt tcttcttatg tgctaaatat
    17041 cctaacgcaa gaactaaacc tatggttgca ccaccgccac ctatgaatac aaaattatcc
    17101 ataaatacgc tagtaaaaat atttggaaga gtttctccag tttgataagc tactttattt
    17161 gcatctagat tagctaacca taacggtttc ataactgcat taacaacatt tcctccgtgt
    17221 aatcctacaa accaaaaact actattaagg aaaattaaga taagaagacc aataacatta
    17281 tttcctaaaa gtccaagtgg acctcccaaa gctccttgag caatttcatg aagattaggt
    17341 aaacttaatt tatctaaagt tgcataaaca atcaaccaac caacaatagt cactgcacca
    17401 ggaataatgg cactaaagct tttagatact gctggtggaa caccatccgg catttttatc
    17461 tgtatattat gatttataaa ccattggtag atatagccat taatcaatcc taaaatcata
    17521 gcaacaaata aaccttttga tgccatgaaa gcggtaggca ttcctgctcc agcctctcct
    17581 gtaatgaaag gcgtaactgt aataaaagat gataatgaca caataccagc aggaatacca
    17641 tcaactttgt attgtctagc cataaagtaa gcgataccaa aactagctac aagaccaagt
    17701 aatccaaaac tactatcaac acccttccat aaatagtcag caacaccaat atcacctaga
    17761 tatttttccc atcctggaat aggaaaactt gcaataacca ttagtaatga acctatcaac
    17821 aataaaggta tagttagagt aataccgtct cgaatagaaa ccaacgcttt attattaccc
    17881 aatctagccg ctactggaag taacttttct tgtaataatt tttccataac cttttcctct
    17941 taaatatatt ttattatcaa aagttatcaa ttatctttat tttttgacgt caagttatta
    18001 tttgattatc ttttgttatt tatattttac aactataaga aagccttgtc aaggatttgt
    18061 gtaaatattt gattattttt tattatcaat atataataaa aagagaccag taagcaatga
    18121 aaagcttaaa aagattaaca tctacattta tccatagcaa aaaatcatag gattttaaga
    18181 atctgacaac taggaagaaa actaatatga ccttatctaa gaaacaatta caactaagag
    18241 ctaaaatact ggaaacagtt tacacattag gtcccatttc acgaattgaa atcgctacta
    18301 aaacaggaat aacacctgca acaactagca gtatcacaaa tgatctgatt aaagaaaata
    18361 ttctcttaga acttggtgaa gacgaacacg atacaagcgt agggagaaaa aaaatcctgc
    18421 tagacattca agctaaacga ttttactaca ttggttgtga actatctgaa aaacatttca
    18481 cttttgcttt aggagataat ctaggaaata tcttaaagga agagaaagaa attgttacta
    18541 aacagttaat ccaagaaaag ggaaatcaac tcattaacca gacactaaag caattcttaa
    18601 ataactgctc tgattatgaa atagaagcaa ttggaatcgc gctacctggt cgctatttag
    18661 atgattataa aataacaaca aacaatcctt tatggcaaca tatcgactta gaaatgattc
    18721 aatcccactt tgataagcct ttgtttttct ctaacaatgt taactgtatg gctataggta
    18781 aacgcctatt tagtcgccaa cagaatgacc ctaattttgc ttattttcat tttgctagag
    18841 gtatgcactg ttcttatatc tacgacggaa acatttatgg gaaaggaaat ctaatgattg
    18901 gagaaatagg gcatacagtt gtttcatctg agggagaaga atgtagctgc gggcgcaagg
    18961 gatgcttaca aacttttgct ggagaatctt ggttaatcaa aaaatcaaaa attctatatc
    19021 atcaatctcc ctattctcta cttcctagtt tagtcaaaaa tgccgatgat attgatatcc
    19081 aagttatttt aaccgcttat caattaggtg acactggaat aatcacactt atccatcaag
    19141 ccttactcta tcttagtcaa accattttaa atatcagtat gatgattgac tctcaaaaaa
    19201 tctacctaca tagtccttta ctaacaaatc aacacatcat ccaaaaacta tatagtgaaa
    19261 tgaactacaa acccaaactg ctctataatc gcctacctga agtcattatt gaaccttaca
    19321 atgattttac agccgcacac tcagctattg cactttgttt gtatcataca attctacatt
    19381 cttaattttc tattacattt aataaatagg ctaaaaagag ggagtatatc ataaaaagcg
    19441 aataaacctg ttttctgaaa atcagaattc tgttttgttc gctttcttta tatttggaat
    19501 tatactccta tctccccttt ttcataatgt atagtgaaat gaaataataa caggacgaat
    19561 cgatcgggac agtcaaatcg atttctaaca atgttttaga aatagaggtg tactattcta
    19621 gtttcaatcc actatatttt cgtacaggtg cttcaaccat ttgaacgatt tcaaatcctt
    19681 ctttttggta aagattctga gctctttgat ttgcctcgaa gacatttaga gaaatactat
    19741 ctatatcttc attttcaaag gccaaactaa caaatttcct taaagcctgg ctacctaagt
    19801 cttgctcctg tttctggggg ttgataaaaa atctcccgat atgaagattg ctgtcttcta
    19861 gcctgatttt ctggataagt cccacaaact cttgttcatc aaagattgaa aagactcctt
    19921 ccaaggcttg aaggggcagt agaaaaggaa tccttggtcc catccattgt tcttgaaagg
    19981 atttgcctag ggagttggac cactggcata caaattgagc gttttctata ctcacctttt
    20041 cttcaaaacg aattgtcatc ttttcctcac catcttatct atgtttctcc attatactat
    20101 ttctcccatt ttttacgaat agataagtat gattgatttt tatttttttc tcgtcgggag
    20161 cattctcgct tcctttcttg gtttggtcat tgaccgtttt ccagagcaat ccattatcag
    20221 ttcagccagt cactgcgatt cctgtcagac tcccttgcgt cccttagatt tgattccgat
    20281 tctctcacag gtcttcaatc gctttcgctg tcgctactgc aaagttcgct atcctgtctg
    20341 gtatgccctc tttgaactag gcttaggact cctctttctg ctttactctt gggaattgct
    20401 ttccttgggg caagtcgtcc taatcaccgc tggtttgacc ttgggtatat acgactttca
    20461 ccatcaggaa tatcccttac tggtctggat gactttccac ctaatcctaa tagcttcctc
    20521 tggctggaat ctggtcatgg tctccttcct catacttgga attttggctc attttattga
    20581 tatccgcatg ggtgcagggg atttcctctt tttagcttct tgtgctctcg tctttagcgt
    20641 aacggagtta ctgatcttga ttcagttcgc ttctgcgacg ggtatcctgg cctttctcct
    20701 gcaaaagaaa aaggaaagac ttcctttcgt gcctttcctc ttacttgcta cttgtgtgat
    20761 tatttttggt aagctactac ttgtttgata aattccaatt tctgccatat gtactccatg
    20821 aaattatttc acagttaaat tataaattat ttcttttgta caaagggatg atgttatcaa
    20881 atcgatctgt tcttctatct tcttgatact gatcaaaaaa tttcatttcg actgaaaata
    20941 tttcgcttat aaactgtaaa cgaatacttt gtttagacat tatagtcgct agactgacta
    21001 gatgattact caaaacgacg tccagaatac tctttacttt gcttggtttt ttaacaaaaa
    21061 tttgatcatc caaaggttca atcattttgt aacctttttg cgcaatttga cgataaaagt
    21121 aagaatgttg ctttggagtc aataatccta acttaaaagc tcgatactct aaagcctgta
    21181 tcgaaacatt caaatccgac ttcaataaaa tataactatc aggattgctg acacgcttgc
    21241 caaccctctc ttcaaatttg actaaaaact cttcttttgg caataaaaaa catgatgcaa
    21301 aataatttgc ttcttgctcc aaacgatcgc catcttcatt catatcttta tatttatgta
    21361 aaagaatatg tcctagctca tgagctaaat caaaatttcg acgtacagat gatttattcg
    21421 ttcccaacac aatataaggt cttcccaatt ttgaccatgc gctataagca tcagcttggc
    21481 cattaattaa tcgttccacg atatagatgc ctgaacgttc taatttataa agcaaatcat
    21541 gattatcttt tgaaatacct aatttttccc tggcataaag agccaattcc tcaatggatt
    21601 ctcccttatg ataagattca ctcactacat tacttaggtc atgaattgta atattaggta
    21661 taattacaaa actttcaaaa taatcaatca aactatctac cttatgtaaa tacatagttt
    21721 gaatatctat tgttttccgg gttgctaggt ctgcatttct aaaggcaatt acagaagaat
    21781 caaatcgaat gctctcttct tcctgttcaa aataagttaa atcaacatga aattggttgg
    21841 ccaaatgcat tttggttgat aatttaggtt tcgtttcgtt ggactcaaac tgccaaatgg
    21901 cttgttccgt taaattaatt ctctgagcta attctgctct acttaaacca tttaacagcc
    21961 gtaattcttt caatacccga ccattaaaca tttacatact ccttactact tttgaccttc
    22021 ttgtttttct attcttggaa taatttcaaa atcttctgtt tccgataatt ctgaaaaatt
    22081 aggaatatct tgatatttag cttcttcgaa atggtacgaa cttgattgaa tatactcaga
    22141 caaatcttga atcaagtgta actgaccagt tcgtgcatca ggcataacaa catctacaga
    22201 tataatattg ttttctgagt ccgcctcata agttaaaatc ataaattttt cgatattcga
    22261 atttttagta gcttgttcaa tttcttgaat catttcatca gaaactaact ccatctgaat
    22321 tggaaaggaa tgactatctt catcattttt gtaggaagaa tgttgattaa gataaagtgt
    22381 attcatctga gcatattcaa ataagtagcc actcttattt ttttgtacca aaggaaattg
    22441 gttcgtaagt cgcttcttac cctttataat taacaatact ttcccatatt tttctgtgtt
    22501 tgtttcaaat tctaaatatc cccaagtctg tcctgctaat tgtaatttat actcaaacaa
    22561 atctgctgat gcaaatgcag tatcaatatg attaggtcgc gtccatgcat aaccattcga
    22621 cactatcatt gtctctcttt tttctagacg ttcatctaca taatcttttt gccctttcat
    22681 caaagtatct acaatttttt gtgcctcaag cgaatcaaag agatcctgat tcaacataat
    22741 tcttcctcct ccaaatactt tttaatgaat tatatcattt tcttaaagaa attactacaa
    22801 taattagctt tttcttaaag ttctgtgtca gagtaattta gaaaattata tcttctatag
    22861 taaaatcaat taaaaactga acaaatttat tgggaaattc aaatcacttt ctaaaaatat
    22921 tttaggaacc gtagtgtaat attccagatt caatttacta taaaactagc ctttctcctg
    22981 caaaagaaaa aggaaagact tcctttcgtg cctttcctct tacttgctac ttgtttaatt
    23041 atttttggta agctactgct tgtttgataa agtcctgaat cggctctcct tggtggagag
    23101 cttttactat tttcgaaccg acgataacac catctgacac cgcattgaag cgttccagat
    23161 cggcttgact agatacacca aaacctgtca agactgggat gtcggccact tgatgaagtt
    23221 gcgccaagtg cttgtccaaa tctgcacggt aattgcctga tttccctgtt accccattga
    23281 tggcaacggc atagacgaat ccctccgccc cttcaatcaa ctctttctgg cgctcaattc
    23341 ctgtggtcaa gcttactaaa ggaatcaagg cgatatctgt atctgccaaa aatggttcta
    23401 caaagttggc atgttcatga ggcaggtctg ggataatcaa gcccttcaca gctgtatcag
    23461 ccagatcttt gacaaagttc tccacaccgt actgaaagag ggggttgaag taggtcatga
    23521 tgaccagtgg aatctctgtt tcaatggttt tcaaggtttc aactaaagcc tgggtagagg
    23581 tcccgtgggc taaactgcgc aagccagctt cttcgataac aggtccatct gcaacagggt
    23641 ctgaaaaggg aatacccact tcaattgcag agacacccaa atcttctaaa aagtgaattg
    23701 tttcagcaag accatccaaa cctttttcgt ggtcaccagc catgatatag ggaacaaaaa
    23761 ttccttttcc agctgcttta atagcattta atttttttgt tagtgtctta ggcatgagct
    23821 tctcccttct ttgctgcatc tgcttccaag cggtctttta cttgaaccac atccttgtcc
    23881 ccacgacctg ataggcatac aatcatagac ttttctggtc caagttcttt ggccaatttc
    23941 accgcaaagg cgatagcatg gctagattcc aaagctggga taatcccttc cacacgagac
    24001 aagagttgga atccttccaa ggcttcttcg tctgtcacag ggacatagct ggcacgttta
    24061 atatcgtggt agtgagaatg ctctggaccg ataccaggat agtccaaacc tgctgagata
    24121 gagaaggctt caagaatttg accatgggca tcttggagca catccatgag ggaaccgtga
    24181 aggacacctg gacgaccctt ggtcaaggta gctgcgtggt gctccgtatc cacaccaaat
    24241 ccagccgctt cagctccata catggctact gactcatctt ctacaaaggg atggaagaga
    24301 ccgatggcat tcgacccacc accaacacag gctactaggg catctggcag attttgtcct
    24361 gtcaagtcac ggtactgttg tttagcctct cgaccaatga cactttggaa gtcacgaaca
    24421 atttctggaa atggatgagg ccccaaggca gaaccaagga tatagtgggt atcatctata
    24481 ttagccaccc atgaacgaag ggctgcattg accgcatcct tgagcacgcg cgaaccatct
    24541 gtcacggcct cgaccttagc tcccaaaagc tccatacgga agacattgag ggcttggcgt
    24601 ttgacatctt cctcacccat gtagatggta cattccatgt taaagagggc cgcagcagtt
    24661 gcagttgcca caccgtgctg accagcacca gtttctgcga taattttctt tttacccatg
    24721 cgtttggcaa gccaaacttg tcccaaggca ttgttaatct tgtgggctcc tgtatggtta
    24781 aggtcttccc gtttgagata aatcttggct ccgccgatat gctgggtcaa gttttttgcg
    24841 taataaagag gagtttcacg tcctacgtac tggcgcaaaa gctggtttaa ttcctcttgg
    24901 aaacttgggt ctgcctgact ttcacggtag gccttctcca actccaaaac tgctgtcatc
    24961 aatgtttctg ggacaaaacg tccgccgaat tttccgtaaa atccatcttt atttggttcc
    25021 tgatatgcca tgctttaccc tctctataaa tcttctaatc ttttcatgat ctttttgtcc
    25081 atctgtctcc actccgctcg atacatctac tgcataggga gtaaaatgtt gaattgcttt
    25141 tactacatta tcttcattaa ggccacctgc gataaagaag ggctgtgcta gtccagtcgt
    25201 atccagttga ccccaatcaa aggactgacc acttcctgcc acaggggcat caaagagtag
    25261 ataatctgcc tgagaattgg ggacatgccc atttccatct acctgcacag cctgaatact
    25321 ggcacaaggc aaattctcaa ataaatcagc tgccacctga ccgtgaactt gaaccaagtc
    25381 caagccaact ttgtcaatcg cttccagcag ttctacccga cttggtgaaa caaatactcc
    25441 aacctttttc acatctgcag gaataagctt tgccaactca gctgcctctt ctaaagtcac
    25501 ctgtctttta ctaggtgcaa agacaaaacc gatatagtcg gctcctgctg aaacggctgt
    25561 ttccaccgct tctttggtcg atagtccaca aattttaacc tttgtcaatc tgcaactcct
    25621 tgattctctg ggccacattt tctgcctgca taagagctgt ccctaccaaa attccgttaa
    25681 agtatggggc tagtcgttcc gcatcctgcc ctgtgaaaat ggcagattca gaaatgtaat
    25741 agcgaccttc ctcaaagtaa ggggctaaat ctacactggt ctgcaagtcg acctcaaagg
    25801 tagtcaagtt gcggttgttg accccgataa tctcagcacc aagtctgtgg gctacctcta
    25861 gttcagctag attgtgagtc tccactaaga cttccagacc aagctctgtc gcgtagtcat
    25921 acagttcctt gaggcgttct tcggacaagg ctgccacaat aagcaagata actgtcgcac
    25981 ctgtattgcg agcgcggatg atttgctttt catctatgat aaagtctttg ttgagcgtcg
    26041 gaatctctac ctgactggaa atttcccgta gataatccaa atgcccttta aagaaaacct
    26101 catctgtcaa caccgaaatc atcactgctc cgttttcttc ataagtctgg gcctgttgca
    26161 caatatccac atcgagattg atatctccca aactagggct agctttcttg acctcagcga
    26221 ttacctgcaa gcagtcctga tgattcttca aaaattctgc caagcgatag gtctggcgca
    26281 gaggctggat ttgctccagc ttcatctgct ccacctcacg cgccttctgc tctaagattc
    26341 gtgctaaaaa ttcctgactc atttttggta ctcctgtaac agtctgagtt tttcaagggc
    26401 cttgcctcta gcaatcactt gacgggccaa ggcaactcct tccttgatgc tatcaatctt
    26461 accattagca tagaaaccaa gaccagcatt caagactgtc gtttccaaga atggacttgc
    26521 ttcgtttttc agaacgctaa gcaaaatttc tgcattttcc tgagcattcc caccacgaat
    26581 atcttccata gcatagtctt ccattcccaa atcctctgga gtaaagcttg acaagctgat
    26641 ttcgccattt tcaagaagtg caatcttggt tgttccgttc aagccagctt catccaaccc
    26701 ttctggtcca gcaaccacga tggcacgttt gcgacccata tttttcaaaa cctgagctgt
    26761 actttctagg agttctggac gactaattcc aagaagctgt gtttctaaag ccattggatg
    26821 aatcagtgga ccagtcaagt tcataatcgt tggaattccc aattccaaac gagctggcat
    26881 gatgtatttc atagctgggt gcatattttt agcgaagaga aagacgattc cagttttatc
    26941 aaagacctta cctagttcag ctggtttgag gtcaagattg attcccaagg cttcgaggac
    27001 atctgcggaa ccagatttag aagaaatcga gcggttacca tgcttggcca tgtgaatacc
    27061 gccaccagcc aagacaaagg ctgcagttgt ggaaatatta aaactgaaag acttgtcccc
    27121 acctgtacca cagttgtcca tagcatcatg aatctcagtt ggaatatgct gggcatgtcc
    27181 tctcatgact tgggcaatgg ctgtacgttc ttcaggtgtt tcccccttca tcttaagagc
    27241 taagaggaga gaagcaatct gcgcttcagt tacacgccca gttacgatac gctcaatgac
    27301 atccgtcatt tccacacctg ataaattttc aaattttgct agtttttcaa taatctcttt
    27361 catcctagtt tcctcacttt acaaccttct cgataaaatt ccgaatagaa gacaagccgt
    27421 ctggcgttcc aatgctctct ggatggtact ggaagccata aatcggtagg tttttatgtt
    27481 gaatccccat gatggcttgg tcatcagtcg aacgagctgt cacttcaaag tcttctggca
    27541 tttcctcaat caaaatactg tgataacgca tgaccgcacg tccatcctca ataccttgat
    27601 acaaaacaga tggcgcttca aagttgatat tgctctgttt cccatgcatg acttttggag
    27661 ccaaacctag cttaccacca aagacttctg caatggcttg gtgacccaaa caaatcccta
    27721 gaatcggctt cttgcctgca aaatcacaaa tcatgtcttc catctttcca gcatcaactg
    27781 gccaaccagg accaggagaa aagaccagac catctgcttt ttcagcttct tcatacagct
    27841 tggaatcatc atttctcaaa acctgaactt ctgcaaaatt cccaatgtat tgggccaagt
    27901 tataggtaaa agaatcatag ttgtcaatca ataaaatcat ggtcttagtt ctccaattct
    27961 agtcatagat tttgctttgt taatggtttc ttggtattcg ttttgggcga tagagtcgta
    28021 gacaatccct gccccagcct gcacataggc tctttgattt ttgagaatca tggttcggat
    28081 ggcaatggcc aaatccatat cacccgtcgc agacaagtag ccgattgctc ctgcatatac
    28141 gctccgtttt tccgtttcca gttcatagat gcgtctcata gctcgaattt ttggtgctcc
    28201 agaaacggtt ccagcaggaa gcgttgcttt caaggcatcc atggcagtga gttctgcaag
    28261 caaacgtccc ttgaccacac tggtcaaatg catgacgtag cggaagagct ccacctccat
    28321 atacttagta acttggacac tggccgtttc agagatgcgg ccaatatcgt tacgccccaa
    28381 gtctaccaac attcgatgtt ctgctgtttc cttctcatca gagaggaggt cagtcgccaa
    28441 ggccttgtct tcttcatccg tagcccctct tggtcgcgtc cctgcaatcg gattggttgt
    28501 cacgatgcca tttttgacag aaaccaaact ttctggacta gctccgatga tttgataatc
    28561 cccaaaatca tagaaataaa ggtaattaga tggattagtc acgcggagat ttctgtagaa
    28621 gtcaaatgga tttccagtaa cttctgctga gaaacgctgg ctgagtacac attggaacat
    28681 atctccgtta cgaatcaagt cacgagctgt ttctaccatt ccctcaaact tatgtggagc
    28741 gatatgcggt ttgaagtcaa gtggtgataa atccaagtct tcaaattcat ttggagcagg
    28801 aatgcgtaat tcctcaagca cttggttcaa ggatttttcc aaggcctctt gactgcgctc
    28861 actataaagt gcatcctcta tgacatgtat cttctccttc ttgtggtcaa agaccatata
    28921 gctctcatag acaaagaaat gcatgtctgg cgtcccaatt gtatcctcag ggatttgacc
    28981 aatttcttca taaagcgaaa tcatatcgta accaacaaaa ccaatggctc ccccaccaaa
    29041 agggaggtct gaatggtgct ggctcttatg agtcacttca taaaggaaat ccaagggatc
    29101 ccgatcaatc gcttgaccat tttgatagag aactccattt tcaaacttaa tctcaaaaac
    29161 tggattatag gctaggatag aaaaacgagc tgtttccttg tctctcggaa tactctctaa
    29221 aataacctta tgttgcccct ttaagcgcat ataagccaag attggtgata agacatctcc
    29281 atgaatgatt cgttccattg tcatttccct ttcagttcta attctagttc gtggcgactg
    29341 tatgaaaaat ccccacgcaa aataacttgc gtgaggacga aattcgcggt gccacctcaa
    29401 ttataggatt tctcctatct ctcattcctg tctcagatat ctcctgtaac aggctgtgcg
    29461 ataaagggca ctcccttgag aatgatgttt tcttctctcg tttcagatga acccaacttt
    29521 acagctttct ctgcttgttt tcagcaacca caagctctct gtgagagaaa agactgtaat
    29581 ttttccatct attatttttt agcttctagt aatctgcaat cgcagctagg tccttgcctc
    29641 cacgaccaga gacattgatg aagagatgtt catctcggta cacctttata ctcttcgaaa
    29701 atctcttcaa accgcgtcaa cgtcgccttg ccgtaggtat ggttactgac ttcgtcagtt
    29761 ctatctgcaa cctcaaaaca gtgttttgag ctgacttcgt cagttctatc cacaacctca
    29821 aaacagtgtt ttgagcaacc tgcggctagt ttcctagttt gctctttgat tttcattgag
    29881 tattactagc ttttttcgta ttagtccagc ctttttgttt acttttagta ggaggcaagg
    29941 agctgtagat agaactcaag ttcatcaaag cgacttaagg ccctaataaa agataaacca
    30001 aacgacggat agaaaaaagc ccacacacag aatatacttc cgtgtgaggg cgttggtaac
    30061 gcggtgccac ctcaattata aagggactat ccctttacat ctctgccttg tttaacaaca
    30121 agctgcactg taaggtgtgc gcaccgaatt ttcattgttt caaattcatt ttcaaaatca
    30181 gcccactttc actacttcca accacctatt cacaatcacc acaggctccc tgaagatcaa
    30241 aaatagttac ttttctgatt tgttgaactt attttaatac tttgtttttt ctttgtcaag
    30301 acttttttac gatttttttg atatcattcg aatgtgacca tatcttcctt agatcgaaca
    30361 tgaacatgtc ccacttgtta gaaattggat ccaactcaat agaaactgaa tggaggctaa
    30421 acagaactta ttttagaaca ctccatcttt tccactagga ttttcaagaa ttaaacaata
    30481 ctagaaactc tgtctcctaa caaatttagg agaaacttca acagatgtga cactttcccc
    30541 tttaataatt gctaaaacac cttctatcat ttctttagcc aatttaacat aattgggagc
    30601 aattgtagac aaagctggag tataatactg agaaatagga atattatcaa atccaatgat
    30661 agaaatatca tctggaataa gaattccttt ctcatagcac gcacgaatca agccctgaac
    30721 cttttcatct cctgaaacaa aaataatgtc cggataattt tgggtagtca agtgctgcat
    30781 tgcataagaa taaactgaat caattgtaga taagccataa atgactttta aatccataaa
    30841 gtaattttta tcattcagaa aagaacgcac acctctttca cgatccttat taacatggga
    30901 ttctcctccc ataagcaacc acatattttt aaatttttct tcagttacag ctttcatcat
    30961 atcataagta gcttgaaaat tattattaga tacatagact actccagacg tttgagattc
    31021 accgaaaaca agaaaaggca tatggttctt ctttaaatac tgaattctga tatcatctac
    31081 actttcataa aaaacaataa caccatctac taggctacct gtgcttgata taattgaatt
    31141 actaattgta tcctcctctc caaagtactc aactatagca ttaacaccaa attctttaca
    31201 cgtccgtaac actttatcta acagcgtatg aaaccaaatt aaaggaaaag agtcgatttt
    31261 ttttacagaa atcaatatat ttatagcttc ttttttagtt aaattttttg catacgcatt
    31321 tggaatatac gacaattcct ctataacttt ttgaatcgct tgataagttt cttctttaac
    31381 atttactcca ccattaataa ctcgtgaaac tgtttttgga gaaaaacctg ataaacgtgc
    31441 aatatcataa atagttacct ttttcccatt tatatttttc atttcagtcc tccattacga
    31501 acattctaat attactatac aatatttaat tttttttaac aagagaattt agtaaattat
    31561 ttaagatcca caaattcaca aaattaattt tacaaatatt cttccccttc aaaaaaattt
    31621 aaattgcatt tcacaccttt atttttaaga atgtttccaa cttcacgaca aataaattca
    31681 tatgagaaaa aactgccata aaattgtaga ttaacttttt cagtaaaatg tgtaggattt
    31741 ataaaaacat ataatagcct gtcaatgtaa cattttaaca tagagttaat tttttcttta
    31801 aagataacat ttgttatcaa ctcatcagga ggtaaatgaa aggcaaacac catttcacaa
    31861 atatcataaa aagaaataaa tttgtatact tgtatcaaac aattattatc aaaatattct
    31921 attttaccta aatcaaaatt gattttataa tctttcataa aaacctctga gcaaaaatct
    31981 actcaaaaat tagatgatta aaacatctaa aaaacaaaag gacaaaaaca tctgtccctt
    32041 tgtttactaa atttcagcta atttcttcga cataaataac acctacaata ttagcaattt
    32101 cttccatcag tcgaagatgt tcaaatctac ctgataattc cagagtaata aatgacgcta
    32161 tttttttatc tggaacatca aagtattcaa ttctgtcaga attaacatct ccaaacgctg
    32221 ttcttgaatc ggtcattctg ataccatttt ctgcacaata aaccaataca cgattatagg
    32281 cttctgtaga tttaaccact atatacaatt caatcatttt agaacgattt tgtagatatt
    32341 tttttagtgg ttggaacatg gatatcacac cccaaacaga aatggctact aaaagagctc
    32401 cctcataaaa acctactcca atagctaatc caattcctgc cgaagcccaa atgcctgctg
    32461 cagttgtcag acctgtaatt ttctttttat ctgtaataag aatcgttcca gcgcctagaa
    32521 aacccacacc tgatataact tgagctccta atcgtgtagg atctcctgtc ccaaatttat
    32581 aagatacgta ttcattcgtc atcataatca aacatgcagc tagacaaaca atactataag
    32641 ttcggatgcc tgcaggctgg gatttgctcc ctctctctaa accaattata ctaccaatga
    32701 ctactgataa aacaatcctg acaactattt caatatttga taacccaaga ctagtggctg
    32761 tcatgattat ttccttactt tacgccccgg tctttgtgtg aagtataata ccgttccaga
    32821 aataatcatc agaacaattg tataaacaaa taccagagct tgtgcattag atgttgctgt
    32881 ttcatcacct gcagatcgaa tcgtaatacc taatggttga gctaggggat ggtaaaggaa
    32941 tacagataag tcgaagtcag ttaataaaga gttaaagttt aaagcaataa cagagagaac
    33001 aaccggtaaa ataaatggaa tgataacctt catcatagta taaaaaggtg aagcacccat
    33061 acttcttgct gcatcttcca tctcatcatc aacactaaat aaaatagcac gtaccattct
    33121 ataagaaaat gggattttta caactatata tgcaataagt agaattacca aactacctac
    33181 caaaatctga ttcaagacaa gaaattgtgg ctgattaaaa gtaaataata aacttactgc
    33241 taaaagcgta cttggtaata accaaggaag tagagcacca tattcaaata agaaatcaaa
    33301 acgagattta tgttttctga caacacgagc aaatacaact gcgagaattg ttgctgttgt
    33361 cgcagcaata atagaataaa taaagctgac caagaatgga gagaatgccg cactattact
    33421 aaagaataag cgataatttt ctaaagtaaa gtttgataat gttaagttac ctgtttgaat
    33481 tgcaactgga tctgtaaatg agtataatac tataaaaatt agtggaagca tgaaaactgt
    33541 gaacaatcca tatgctacaa tgtgagcaat gatattccaa ggcttagacg caattttttg
    33601 ttttttaaga ggcgctttag tcttagagat agaaatataa tttccacctt tttctatctt
    33661 attcatgata gtaagcaaaa ttgtagttgc aatacctaaa ataattgcaa gtaaggcagc
    33721 taaatcacga gaattcccca tccctgcaaa tgtaataatc attggattta tagtttgaaa
    33781 ttctttacca ccaacaatca tgggtgctgc tactgcagat aaaccactaa gaaaaaccat
    33841 aatagtaagt gcaaatagag ttggaattaa ggttggtaac actacttttc ggaaaacagt
    33901 aaatggtttt gctcccatat ttcgagcagc ctcaatagtg tgatagtcaa cgcttcgaat
    33961 tgtatttgtt aaaaacaatg tatgattagc agttcctgaa aatgtcataa tgaataagac
    34021 tgcaccatac ccaataaacc agttagggtc taaagaaggg ataacatttt gtaaaaattt
    34081 tgtaatcaat ccatatggac catagacaaa tttatatcca gtcgctaaaa ccactcctcc
    34141 ataaattaaa gaggtcatat aacctaattt taaaatttta gcacctttaa tatcaaagta
    34201 ctctgtaaat agaacacaaa gaatacctac gacattaact gtaataatga gtgaaaatgc
    34261 taacttaaaa ctgttcataa tactctgaag tgccctctga gattttagaa cacgatgtac
    34321 agcatcaagg gaaaattctc ctccttttac aaatacattc actactagat caaagtttgg
    34381 ataaataata aatgttacta agaaccagat taaccctaaa cgaataagcc aatcttttaa
    34441 atttaattta tgacgcatac tgcacctcct taaaattgca gaacgtctga tggtgtgata
    34501 aataattcca cactttctcc gacagatcta atagcagcct gactatcaat acttgttaca
    34561 ttaagaatct gactttcaga aacttttatt gtatagtgaa ttgtaactcc agaaaactca
    34621 acatcaataa ttgtcccttt tagaatgaaa tcttgttcag tttcacgatt gaatcgaact
    34681 ttctctaatc gaatgtatcc ttttttatct tctaagaaaa cgcttgtatt tttcagtaat
    34741 acttcgtgga ctgtttcatc ggtcaaaaca ttaatatctc caataaaatc acatacaaat
    34801 tcagtttgag aattatgata aatctctact ggtgtaccga cctgttcgat gtatccattg
    34861 ttaaagactg caattctatc agataaagtc aaggcttcct cttgatcatg agtaacatat
    34921 aaagtagtaa tacctaactc tttttgaagt cttttcaact cttttctcaa atctacacgt
    34981 aattttgcgt caaggtttga caatggttca tctagacaaa gaattttagg ttcaagaacc
    35041 agagcacgag ccaatgctac cctttgttgt tgacccccag ataattctga tacattacgc
    35101 tgtaactgtt gatcagagat cttaattttt gctgccactg ctgatacttt agctttaata
    35161 acatctggag ctaccttctt aacttttaaa ccaaatgcaa tattatcaaa aacagtcata
    35221 gttggaaata gcgcataaga ttgaaataca ataccaattc cacgcttttc aggttccaaa
    35281 tgagtgacat ctgttccatt aacttcaata cttcctgatg atggatctaa aaaacctacc
    35341 aatgctctca aagtagttga tttaccacat cctgaaggcc caagaaatgt aaagaattcc
    35401 ccttcatgta tatctaaatt cagattatca attgcaacaa aatcaccata tttaatttga
    35461 atattatcaa atttaatcat ctcactaact ccctctatta ctaaaccaaa agcctctctt
    35521 tatttcttcc ttaaatttag aaataataga gagacttgga cataaaaaat aactcttatt
    35581 tcttatttta cgtattctaa ttcagctttt tctacccatt catccaaatg ctttccaaca
    35641 gcttcccagt caatattttg tggtttcact tgatcaacaa attttttcgt atcttcaggt
    35701 aactctttta gggcatcttt atttgcagga atagatccaa attttttact atattctact
    35761 tgaatttctg attgaccaaa ccaatcaata aattctttag ctaacgcttg ttttttacta
    35821 gtgcttaaaa ccatagtttg ttcagttaca aatggtacac caatctcagg agtcataact
    35881 ttgaattcaa cattttgttc tttttgtccg attaacgctc cagaacccca gatcataccg
    35941 tattgaattg ggctttcttt atctaacgct ttaacaactg agctttcacc tttttgaaga
    36001 gtataggcat ttgcaaagta ttcttttgca acttcccatc ctttttctga tacgcctaaa
    36061 tctccttttt catcaaggta acgaactaag atacttgcta gaattgcccg tcctgtacca
    36121 ccttgaagac cataaattga atatttacct ttatacttac tacctaattc agtccaatct
    36181 ttaggcattt cttttacatc aggcgcccca attaaaacta atggttgaac aatcacagga
    36241 ttataataat tatctttatc tgataaagat tgatcaattt tatctaacca tttaggcttg
    36301 tactgtacta gtaatttttg atctctaatt ttatttgagt caacagcacc aattccaaat
    36361 accatatctg caactgcatt attcttctca gcaataacac ggtctgctaa ttgagcgcca
    36421 gcaatatcaa ccatttttat attaaaacca gcttcttttg ctttagcagt taaccaatca
    36481 ccacgaccat ttgagactga gttcgaatag attactaatt cttgactttt atcagctttt
    36541 tcttcagatg aagaagcagt cgtagaattt gaacctccag agcaagcagc aagtgtagta
    36601 agagcaactc ccgttgcaag tacagtagac caaactttca tttttttcat gataagttct
    36661 ccttttttat tattttattt aaatttttcg tgatatggaa caaattgtct catatcttca
    36721 aatacagtat agtcaatacg gtttacagta atagttggaa tcttctctaa taaaatttca
    36781 gttaattctg ctctgacttt agtaaactct tcttcctcct cttcggttag aggaatccga
    36841 agatacccaa ttgaaatatg gaattgatat ctatcatgat tagggaaaca aacacctgct
    36901 ttttctgaga cataagtacg aatttcttct aatctctttg cagaagcttc atctgcaggt
    36961 tcaactagta tgttttgttt tcccatttca gttatacgca tatgaatttc ttcatccaac
    37021 aatggaaaaa tttcaagttg tttagcaaag taatcatgta tttcctgtaa aggtgtatct
    37081 agaggaagat tactgctcca aaactccgtt tcacgatttt catggcacaa caattcaatt
    37141 acagtcatgt gaatagaatt ccttggagtt aaagtaaact tatcgataaa tggtaattct
    37201 ctataacgtg attgaataat atcaacaact tccatcaaat cttgtttagt ataaagattt
    37261 gctacaactg tattcccagg gaaatgatta aattccccat tctctttgaa cttaattttt
    37321 gttaagtttt tcatataaag accttctttt ttatatttga catcggtgtc attgtgttta
    37381 cattatacaa tgaaaccgtt tcctttgtca agcgctgtca aacatttttt ttaatttatc
    37441 tttcattaaa a
//
LOCUS       DAVBIC010000018        36090 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.018, whole genome shotgun sequence.
ACCESSION   DAVBIC010000018 DAVBIC010000000
VERSION     DAVBIC010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 36090)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36090)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36090
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.018"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            <1..360
                     /locus_tag="VQ664_000860"
     CDS             <1..360
                     /locus_tag="VQ664_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIB"
                     /protein_id="HET2789047.1"
                     /translation="IFRWFITQFNVLTPGRGEEVDSKEISESADSTSNTADYLKQDSL
                     QIIRALGGSNNIEDVDACVTRLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGA
                     KAILYKNSINEILGVDD"
     gene            485..1813
                     /locus_tag="VQ664_000861"
     CDS             485..1813
                     /locus_tag="VQ664_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2789048.1"
                     /translation="MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            2065..2931
                     /locus_tag="VQ664_000862"
     CDS             2065..2931
                     /locus_tag="VQ664_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2789049.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAVMIAIVSF
                     VQFKVLGNDVEY"
     gene            2947..3786
                     /locus_tag="VQ664_000863"
     CDS             2947..3786
                     /locus_tag="VQ664_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET2789050.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            4059..4511
                     /locus_tag="VQ664_000864"
     CDS             4059..4511
                     /locus_tag="VQ664_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HET2789051.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRKDSFELGKYEIDGD
                     KVFLVVQENVLNQVENNQFEHHKNYADLHLLIEGHEYSSYGSRIKDEAVAFDEATDIG
                     FVHCHEHYPLLLGYHNFAIFFPGEPHQPTGYAGMEEKVRKYLFKILID"
     gene            4608..4952
                     /locus_tag="VQ664_000865"
     CDS             4608..4952
                     /locus_tag="VQ664_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789052.1"
                     /translation="MVSSKHAARASFLDGQEITVDEMSWIINGIVNALIGRYIKLGTY
                     AAKYGIGIARSILSRAAATAAARVGLLTKISGWILRVAVNVADVYGNFANNIAAAWDA
                     YDKIPNNGRINF"
     gene            5236..5880
                     /locus_tag="VQ664_000866"
     CDS             5236..5880
                     /locus_tag="VQ664_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HET2789053.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEVKKSRRVPVFKIYLRSFKQNLKLGLQLGLMELGIVFLTLSDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLSWKEILQKGLMLASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            6049..6966
                     /locus_tag="VQ664_000867"
     CDS             6049..6966
                     /locus_tag="VQ664_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HET2789054.1"
                     /translation="MSDLKKYEGVIPAFYACYDEQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGAKAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTATHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVTEEDRPVVEAAAALIRETKESFL"
     gene            6984..7868
                     /locus_tag="VQ664_000868"
     CDS             6984..7868
                     /locus_tag="VQ664_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET2789055.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASVTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(7884..8735)
                     /locus_tag="VQ664_000869"
     CDS             complement(7884..8735)
                     /locus_tag="VQ664_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HET2789056.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANRVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLLDAKEMGAKTVLFTSVPNKDSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            8935..10992
                     /gene="pbp2b"
                     /locus_tag="VQ664_000870"
     CDS             8935..10992
                     /gene="pbp2b"
                     /locus_tag="VQ664_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HET2789057.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTKRQLADYYLADPEIYKKTVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQALEYSSN
                     TYMVQTALGLMGQTYQPNMFVGTSNLESAMEKLRSTFGEYGLGTATGIDLPDESTGFV
                     PKEYSFANYITNAFGQFDNYTPMQLAQYVATIANNGVRVAPRIVEGIYGNNDKGGLGD
                     LIQQLQPTEINKVNISDSDMSILHQGFYQVAHGTSGLTTGRAFSNGALVSISGKTGTA
                     ESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYH
                     PMN"
     gene            11003..11599
                     /gene="recR"
                     /locus_tag="VQ664_000871"
     CDS             11003..11599
                     /gene="recR"
                     /locus_tag="VQ664_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HET2789058.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDPTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            11775..12818
                     /locus_tag="VQ664_000872"
     CDS             11775..12818
                     /locus_tag="VQ664_000872"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HET2789059.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVNYDRFTVKTFFISQ
                     SGDFIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFTKPSNMGSSVGISKSENQEELRQALKLAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKITMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWDNMGISYPELIERLVDL
                     AKESFDKREAHLI"
     gene            12902..14275
                     /locus_tag="VQ664_000873"
     CDS             12902..14275
                     /locus_tag="VQ664_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HET2789060.1"
                     /translation="MKLTIHEVAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVP
                     LKGVRDGHDFIERAFENGAAATLSEKEVANHPYILVDDVLTAFQQLAAYYLEKTAVDV
                     FAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLAP
                     ADPIVEDYLPTDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQVLDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIRLAFQHLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGVQSVQLHNQMILSLSPDVLDTVIFYGEDIAE
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLGAHDQILLKGSNSMNLAKLVE
                     SLENEDK"
     gene            14262..14873
                     /locus_tag="VQ664_000874"
     CDS             14262..14873
                     /locus_tag="VQ664_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET2789061.1"
                     /translation="MKTSDFVKYLQRMIAITDTGLTFTKDPFDRERYEDLRDLLSEML
                     NQASDLDSEEVAEVLKPTSAYATPLMDVRAWIVEDEKICLVRGQGEDSWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDTNRFQLQSKQYAKFVFECKLLDGQFQEN
                     QEIADLQFFAIDPLPNLSEKRITKEQIEILWQVYQGQREQYLD"
     gene            14964..15668
                     /locus_tag="VQ664_000875"
     CDS             14964..15668
                     /locus_tag="VQ664_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HET2789062.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTFYTAHRYREKK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            15887..17260
                     /gene="ftsA"
                     /locus_tag="VQ664_000876"
     CDS             15887..17260
                     /gene="ftsA"
                     /locus_tag="VQ664_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HET2789063.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENIIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVESVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            17277..18536
                     /gene="ftsZ"
                     /locus_tag="VQ664_000877"
     CDS             17277..18536
                     /gene="ftsZ"
                     /locus_tag="VQ664_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HET2789064.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARSATN
                     YRETVKPAHSHGFDRHFDMAETVELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            18541..19212
                     /locus_tag="VQ664_000878"
     CDS             18541..19212
                     /locus_tag="VQ664_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HET2789065.1"
                     /translation="MNVKENTELVFREVAEASLSAHRESGSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDVIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKATQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            19222..19761
                     /locus_tag="VQ664_000879"
     CDS             19222..19761
                     /locus_tag="VQ664_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HET2789066.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTPVNSSQEPALP
                     MNQPSQSAGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            19761..20024
                     /locus_tag="VQ664_000880"
     CDS             19761..20024
                     /locus_tag="VQ664_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HET2789067.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            20021..20705
                     /locus_tag="VQ664_000881"
                     /pseudo
     CDS             20021..20705
                     /locus_tag="VQ664_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
     gene            20714..21502
                     /gene="divIVA"
                     /locus_tag="VQ664_000882"
     CDS             20714..21502
                     /gene="divIVA"
                     /locus_tag="VQ664_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HET2789068.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPAPIEEEPIDMTRQFSQAEMEELQARIEV
                     ADKELSEFEAQIKQEVETPTPVVSPQVEEEPLLIQLAQCMKNQK"
     gene            21850..24642
                     /locus_tag="VQ664_000883"
     CDS             21850..24642
                     /locus_tag="VQ664_000883"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HET2789069.1"
                     /translation="MKLKDTLNLGKTEFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     QGKPHFTLHDGPPYANGNIHVGHAMNKISKDIIVRSKSMSGFYAPFIPGWDTHGLPIE
                     QVLSKQGVKRKEMDLVEYLKLCREYALSQVDKQREDFKRLGVSGDWENPYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GVLDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPAGEARKFVVAAELLTSLSEK
                     FGWADVQVLETYRGQELNHIVTEHPWDTAVEELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANNLEVAVTVDERGIMMKNAGPEFEGQFYEKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDEIEKVKFHSEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMVAETIEHVAQLFEEHGSSIWWERDAKDLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVVVNRPELTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFALDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDTVAYDELRSVDKYMT
                     IRFNQLVKTIRDAYANFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFEAEDFVQLSELPEVQTFANQEEILD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SELTIAEEPAPEAALSFEDVVFTVERAAGEVCDRCRRIDPTTAERSYHAVICDHCASI
                     VEENFADAVAEGFEEK"
     gene            25052..25414
                     /locus_tag="VQ664_000884"
     CDS             25052..25414
                     /locus_tag="VQ664_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000842495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789070.1"
                     /translation="MKSSGIVGLVGGILLLICPFVLLGTAVNTAATTLNGGATAGAFS
                     GVALLLNALKIANLVLGIIAIVYYKGDKHVGAAPSVLMIVSGEVSLIPFLGWVGGILA
                     IIGGSLFLATLKKFKSEE"
     gene            25949..26641
                     /locus_tag="VQ664_000885"
     CDS             25949..26641
                     /locus_tag="VQ664_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HET2789071.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIEFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            26694..29105
                     /locus_tag="VQ664_000886"
     CDS             26694..29105
                     /locus_tag="VQ664_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HET2789072.1"
                     /translation="MIRNKKQDYVLAYKQPASTTYMGWEEEALPIGNGSLGAKVFGLI
                     GAERIQFNEKSLWSGGPLPDSSDYQGGNLQDQYVFLAEIRQALEKRDYNLAKELAEQH
                     LIGPKTSQYGTYLSFGDIHIEFSQQGTTLSQVTDYQRQLNISKALATTSYVYKGTRFE
                     RKAFASFPDDLLIQCFTKEGLETLDFTIELSLTCDLASDGKYEQEKSDYKECKLDITD
                     SHILMKGRVKDNDLRFASYLAWETDGDIRVWSDRVQISGASYANLFLAAKTDFAQNPA
                     SNYRKKLDLEQQVIDLVDTAKEKGYTQLKSRHIEDYQALFQRVQLDLEADVDASTTDD
                     LLKNYKPQEGQALEELFFQYGRYLLISSSRDCPDALPANLQGVWNAVDNPPWNSDYHL
                     NVNLQMNYWPAYVTNLLETVFPVINYVDDLRVYGRLAAVKYAGIVSQKGEENGWLVHT
                     QATPFGWTAPGWDYYWGWSPAANAWMMQTVYEAYSFYRDQDYLREKIYPMLRETVRFW
                     NAFLHKDQQAQRWVSSPSYSPEHGPISIGNTYDQSLIWQLFHDFIQAAQELGLDEDLL
                     TEVKEKSDLLNPLQITQSGRIREWYEEEEQYFQNEKVEAQHRHASHLVGLYSGNLFSY
                     KGQEYIEAARAILNDRGDGGTGWSKANKINLWARLGDGNRAHKLLAEQLKTSTLPNLW
                     CSHPPFQIDGNFGATSGMAEMLLQSHAAYLVPLAALPDAWSTGSVSGLMARGHFEVSM
                     SWEDKKLLQLTILSRSGGDLRVSYPDIEKSVIKMNQEKIKAKCMGKDCISVATAEGDL
                     VQFYF"
     gene            29355..30056
                     /locus_tag="VQ664_000887"
     CDS             29355..30056
                     /locus_tag="VQ664_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2789073.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANRDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDALNPDQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIQMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            30058..32758
                     /locus_tag="VQ664_000888"
                     /pseudo
     CDS             30058..32758
                     /locus_tag="VQ664_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
     gene            complement(32854..33345)
                     /gene="tpx"
                     /locus_tag="VQ664_000889"
     CDS             complement(32854..33345)
                     /gene="tpx"
                     /locus_tag="VQ664_000889"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HET2789074.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGRDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(33468..34397)
                     /gene="psaA"
                     /locus_tag="VQ664_000890"
     CDS             complement(33468..34397)
                     /gene="psaA"
                     /locus_tag="VQ664_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HET2789075.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            complement(34429..35277)
                     /locus_tag="VQ664_000891"
     CDS             complement(34429..35277)
                     /locus_tag="VQ664_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HET2789076.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            complement(35274..35996)
                     /locus_tag="VQ664_000892"
     CDS             complement(35274..35996)
                     /locus_tag="VQ664_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HET2789077.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
BASE COUNT        10823 a         6664 c         8033 g        10570 t
ORIGIN      
        1 atttttagat ggttcattac tcaattcaac gttctaacgc cagggcgagg agaagaagta
       61 gattctaaag aaatttctga atccgcagat tcaacttcaa atactgcaga ttatttaaaa
      121 caggatagcc tacaaattat cagagccttg ggtggatcaa ataatataga agatgtagat
      181 gcttgtgtga cacgtttacg tgtagctgta aaagaagtta atcaagttga taaagcactt
      241 ttaaaacaaa ttggtgcagt tgatgtctta gaagtgaagg gtggcattca agcaatatat
      301 ggagcaaaag caatcttata taaaaatagt attaatgaaa ttttaggtgt agatgattaa
      361 gtacttactg acttaataaa aaacagagga gagtgatgga tgagtaggat gaaatgaaat
      421 cgcatacaag aaataaagaa ctcattatcc aagttggata cgcttattac ataggagaat
      481 acaaatgaaa tttagaaaat tagcttgtac agtacttgcg ggtgctgcgg ttcttggtct
      541 tgctgcttgt ggcaattctg gcggaagtaa agatgctgcc aaatcaggtg gtgacggtgc
      601 caaaacagaa atcacttggt gggcattccc agtatttacc caagaaaaaa ctggtgacgg
      661 tgttggaact tatgaaaaat caatcatcga agcgtttgaa aaagcaaacc cagatataaa
      721 agtgaaattg gaaaccatcg acttcaagtc aggtcctgaa aaaatcacaa cagccatcga
      781 agcaggaaca gctccagacg tactctttga tgcaccagga cgtatcatcc aatacggtaa
      841 aaacggtaaa ttggctgagt tgaacgacct cttcacagat gaatttgtta aagatgtcaa
      901 caatgaaaac atcgtacaag caagtaaagc tggagacaag gcttatatgt atccgattag
      961 ttctgcccca ttctacatgg caatgaacaa gaaaatgtta gaagatgctg gagtagcaaa
     1021 ccttgtaaaa gaaggttgga caactgatga ttttgaaaaa gtattgaaag cacttaaaga
     1081 caagggttac acaccaggtt cattgttcag ttctggtcaa gggggagacc aaggaacacg
     1141 tgcctttatc tctaaccttt atagcggttc tgtaacagat gaaaaagtta gcaaatatac
     1201 aactgatgat cctaaattcg tcaaaggtct tgaaaaagca actagctgga ttaaagacaa
     1261 tttgatcaat aatggttcac aatttgacgg tggggcagat atccaaaact ttgccaacgg
     1321 tcaaacatct tacacaatcc tttgggcacc agctcaaaat ggtatccaag ctaaactttt
     1381 agaagcaagt aaggtagaag tggtagaagt accattccca tcagacgaag gtaagccagc
     1441 tcttgaatac cttgtaaacg gatttgcagt attcaacaat aaagacgaca agaaagtcgc
     1501 tgcatctaag aaattcatcc agtttatcgc agatgacaaa gagtggggac ctaaagacgt
     1561 agttcgtaca ggtgctttcc cagtccgtac ttcatttgga aaactttatg aagacaaacg
     1621 catggaaaca atcagcggct ggactcaata ctactcacca tactacaaca ctattgatgg
     1681 ttttgctgaa atgagaacac tttggttccc aatgttgcaa tctgtatcaa atggtgacga
     1741 aaaaccagcg gatgctttga aagccttcac tgaaaaagca aacgaaacaa tcaaaaaagc
     1801 tatgaaacaa tagtccttag ttattctata aaaagtagtt ttttaaagaa cctaagagtg
     1861 tataccccct tttccctcta cacagatagt gtaagaaaag ggggcttttg tttaaaatgt
     1921 aagaaactgt cacgaaatta aaatgaagtt cttacataag cgaatcataa aaaatttcat
     1981 tttgatttta aaacagttca agaaagtcaa aaaattattc tatttgaaag agaggtgccg
     2041 actgtgaaag tcaataaaat ccgtatgcgg gaaacagtga tttcctacgc tttcctagca
     2101 ccagtattat tcttctttgt catctttgtg ttggctccga tggtgatggg cttcattaca
     2161 agtttcttta actactcaat gactaaattt gagtttgtag gcttggataa ctatatccgt
     2221 atgtttaaag atcctgtctt tacaaaatct ctgattaaca cagttatttt ggttattgga
     2281 tctgtaccag ttgttgttct attctcactc tttgtagcat ctcagaccta tcatcaaaat
     2341 gtcattgcca gatccttcta ccgtttcgtc ttcttccttc ctgttgtaac gggtagtgtt
     2401 gccgtgacag ttgtttggaa atggatttat gacccactat cagggattct aaactttgtc
     2461 cttaagtcca gccacatcat cagccaaaac atttcttggt tgggagataa aaactgggca
     2521 ttgatggcga ttatgattat tctcttgacc acttcagttg gtcagcccat catcctttat
     2581 atcgctgcca tggggaatat tgacaattca ctggttgaag cggcgcgtgt tgatggtgca
     2641 actgagtttc aagttttttg gaagattaaa tggccaagcc ttcttccaac aactctttat
     2701 attgcaatca tcacaacaat taactcattc cagtgtttcg ccttgattca gcttttgaca
     2761 tctggtggtc caaactactc aacaagtacc ttgatgtact acctttacga aaaagccttc
     2821 caattgacag aatacggcta tgccaacaca attggtgtct tcttggcagt catgattgct
     2881 atcgtaagct ttgttcaatt taaagtactt ggaaacgacg tagaatacta aagaaaggag
     2941 acagctatgc aatctacaga aaaaaaacca ttaacagcct ttactgttat ttcaacaatc
     3001 attttgctct tgttgactgt gctgttcatc tttccattct actggatttt gacaggggca
     3061 ttcaaatcac aacctgatac aattgttatt cctcctcagt ggttccctaa aatgccaacc
     3121 atggaaaact tccaacaact catggtgcag aaccctgcct tgcaatggat gtggaactca
     3181 gtatttatct cattggtaac catgttctta gtttgtgcaa cctcatctct agcaggttat
     3241 gtattggcta aaaaacgttt ctatggtcaa cgcattctat ttgctatctt tatcgctgct
     3301 atggcgcttc caaaacaagt tgtccttgta ccattggtac gtatcgtcaa cttcatggga
     3361 atccacgata ctctctgggc agttatcttg cctttgattg gatggccatt cggtgtcttc
     3421 ctcatgaaac aatttagtga aaatattcct acagagttgc ttgaatcagc taaaatcgac
     3481 ggttgtggtg agattcgtac cttctggagt gtagccttcc cgattgtgaa accagggttt
     3541 gcagcccttg caatctttac cttcatcaat acttggaatg actacttcat gcagttggta
     3601 atgttgactt cacgtaacaa tttgaccatc tcacttgggg ttgcgaccat gcaggctgaa
     3661 atggcaacca actatggttt gattatggca ggagctgccc ttgctgctgt tccaatcgtc
     3721 acagtcttcc ttgtcttcca aaaatccttc acacagggta ttactatggg agcggtcaaa
     3781 ggataatact ctgcgaaaat cgaatgcaaa ctacgtcagc ttcaccttgc catacttaag
     3841 tattgcctgc ggttagcttc ctagtttgtt cttcaatttt cattgagtat aggaaaatca
     3901 atctatcaag atacagaagt atattttata gatttagaga atatagaagt tataagtgtc
     3961 tacaaaatgg agggtatgca gttactttat gaagttttgt cagacactta tcaacttaag
     4021 aatgatttta gttaattatc agaaacgaag gaaagagtat gatttttgac gatttgaaaa
     4081 acatcacctt ttacaaaggg attcatccca atttagacaa agctatcgac tacctctacc
     4141 aacatcgtaa agattcattc gaattaggaa agtatgagat tgatggagat aaggtctttc
     4201 tagttgttca ggaaaatgtc ctcaatcaag ttgagaataa tcaatttgaa caccataaga
     4261 actatgcaga tttgcatttg ctgatagaag ggcatgaata ttcgagctac ggttcacgta
     4321 tcaaagacga ggcagtagca ttcgacgaag cgactgacat tggctttgtt cattgtcatg
     4381 aacactaccc actcttgttg ggttatcata attttgcgat tttcttccca ggtgagccac
     4441 atcagccaac tggctatgca ggtatggaag aaaaggttcg aaaatatctc tttaaaattt
     4501 tgattgatta aaaataggat gaattgtttt tttgtaaagc tttgacaata ctctaccatg
     4561 aaattgatct ttatgaggta gagaaatgag aataaaatat ttaaaaattg gtatcttcta
     4621 agcatgctgc aagagctagt ttcttagatg gacaggaaat tacagttgat gagatgtcct
     4681 ggataattaa tggcattgtg aatgcattga ttggtagata cataaaatta ggtacttatg
     4741 cagctaagta tggtattggt atagcacgct cgatcttaag tagggcagct gcaactgcag
     4801 cagcaagagt aggattactg accaagattt ctggatggat tttacgagta gctgtgaatg
     4861 tagctgatgt atatggtaat ttcgccaaca atattgctgc agcttgggat gcatatgata
     4921 aaattcctaa caatggtcgt ataaactttt aaaatacgag aatgaaagca ctttgtattt
     4981 ttttattgaa tatgttagct tggacagtgc ttgcaatgat aattcgtgga gggctagatg
     5041 gatttgatag gcatacttgg agtactattt taattgcttc gctgttcggg gtatatgatt
     5101 ataagcccat agataaaaat agaaaaaagt ccaaaagaaa aaagaaaaaa tagatttgtt
     5161 catggtaggg acttatgaaa gctttactga caaaaaagaa aacagtttac aaagaaaaat
     5221 gatggaggag caaacatggc acaaaaagga gtaagcctta tcaaggcagc atttgataca
     5281 gataactttc tcatgcgttt tagtgagaag gtcttggaca tcgtgacagc caatcttctt
     5341 tttgtcgtct cttgtttacc catcgtgacg attggagtgg ctaaaatcag cctctacgag
     5401 accatgttcg aagttaagaa gagcagacgg gtgcctgttt ttaaaatcta tctaagatct
     5461 ttcaagcaaa atctgaaact aggtcttcag ctgggtttaa tggagttagg aattgtgttt
     5521 cttacccttt cagatctcta tcttttctgg ggtcaaacag ctctgccctt ccaattgctg
     5581 aaagccattt gtttaggtat tctgattttt cttactatcg tgatgctggc tagttaccct
     5641 atcgcggcac gttatgacct atcttggaaa gaaattcttc aaaaaggatt gatgttggct
     5701 agttttaact ttccttggtt cttcctcatg ttagccattc ttgtcctcat tgtgatggtt
     5761 ctttatctgt ccgccttcag tctactctta ggtggctcag tcttcctact ttttgggttt
     5821 ggactattgg tctttatcca gactggattg atggagaaaa ttttcgcaaa ataccaatag
     5881 gagctttatt tctgaaacta ctttcaaagg ctccaaacgc tattctataa gcgagaaact
     5941 aaaatctaag tgtctataag atattgaaag ccttttcggt aaagtgtata ctaaagaagt
     6001 aaagaaaaat ctgctttagc agaaaataaa aataatagga gaaaatctat gtcagatttg
     6061 aaaaaatacg aaggtgtcat tccagccttc tacgcatgtt atgatgagca aggagaagta
     6121 agtccagagc gtacgcgtgc cttggttcaa tacttcattg ataaaggtgt tcaaggtctt
     6181 tatgtcaatg gttcttctgg tgaatgtatc taccaaagcg ttgaagatcg caagttgatt
     6241 ttggaagaag tcatggcggt agctaaaggt aaattgacca ttattgccca tgttgcctgc
     6301 aacaatacta aagacagtat ggaacttgct cgccatgctg aaagcttggg agtagatgct
     6361 attgcaacga ttccaccaat ttatttccgc ttgccagaat actcagttgc caaatactgg
     6421 aacgatatca gttctgcagc tccaaacaca gactacgtga tttacaacat tcctcaattg
     6481 gcaggggttg ctttgactcc aagcctttac acagaaatgt tgaaaaatcc tcgtgttatc
     6541 ggtgtgaaga actcttctat gccagttcaa gatatccaaa cctttgtcag ccttggtggg
     6601 gaagaccata tcgtctttaa cggtccagat gaacagttcc taggtggtcg cctcatgggt
     6661 gccaaagctg gtatcggtgg tacttatggt gctatgccag aactcttctt gaaactcaac
     6721 caattgattg cggataaaga tttagaaaca gcgcgtgagt tacagtatgc tatcaacgct
     6781 atcattggta aattgactgc tacacatgga aatatgtacg gtgtcatcaa agaagttttg
     6841 aagatcaatg aaggcttgaa tattggttct gttcgttcac cattgacacc agtgactgaa
     6901 gaagatcgtc cagttgtaga agcggctgct gccttgattc gtgaaaccaa ggagagcttc
     6961 ctctaatcta aaaggaggta tttatgacat actacgttgc aattgatatc ggtggaacca
     7021 acatcaagta tggtttggtt gatcaagagg ggcaacttct tgaatcgcat gaaatgccaa
     7081 ctgaggcgca taagggtgga cctcatatct tacaaaagac caaagatatc gtagctagtt
     7141 atttagaaaa aggcccagta gcaggtgttg ccatatcttc tgctgggatg gtggatccgg
     7201 ataagggtga gattttctat gctgggccgc aaatccctaa ctacgcaggc acccagttca
     7261 aaaaggaaat cgaagaaagc tttactattc cttgtgagat tgaaaatgat gtcaactgtg
     7321 caggtcttgc tgaggcagta tctggttcag gcaagggagc aagtgtgaca ctttgcttga
     7381 ccattggaac cggtatcggt ggttgcttga ttatggatag gaaagtcttc catggtttta
     7441 gcaattcagc ctgtgaagtc gggtatatgc atatgcagga tggagctttt caagacttgg
     7501 cttctacaac agctttagtg aaatatgtag ctgaagccca tggagaagat gttgatcagt
     7561 ggaatggccg tagaattttc aaagaagcca ctgaaggaaa caaaatctgc atggaaggta
     7621 ttgaccgtat ggttgactat ctaggaaaag gtctggcaaa tatttgctac gttgccaatc
     7681 cagaagtggt tattcttggt ggtggtatca tggggcaaga ggctatcctc aaacctaaga
     7741 tccgcacagc cttgaaagag gctttggtac caagtttagc agaaaaaaca cgattagaat
     7801 ttgcccatca ccaaaataca gcagggatgt tgggtgcata ttatcatttt aagacaaaac
     7861 aatcctagtt tggctcagcc aaactaggat tttcttacac gtttttgtct acgatagccg
     7921 ttgagttttt tattttccca gtagctatta aagatttttt ccttgctttc gcgattgatt
     7981 tccaaaaagt aggcataaat caaatcgata aagaagagca taggaagttg agcggatatt
     8041 cgttggatat aggagggttg gctgtgggtg gctacaagaa cagtctctgt ataggtctgg
     8101 ctatctttat tgggaacact tgtaaagagt acagtctttg cccccatctc cttggcatct
     8161 aatagactat ctaaaataga aggagttgag cctgaaagtg agaagcccag tactagacaa
     8221 ttttcatcca tgatgctggt tgtccaggca aagccgtctt ggtctgtcaa agcttcgcag
     8281 accacaccta gtcgcataaa acgtaatttc atttcacggg cgacgaggcc agaactccct
     8341 gttccaaaga agtagatacg ctcagcatct tcgattagct gggcaattcg ctctagttgg
     8401 atttcgtcaa tcaagtcttg tgtttgttcc ctcatattgc tataacttct gaggactcgt
     8461 ttggtcagtg gactgtgctt ggagactcgg ttggcttgat tttctgcctg atgttggtat
     8521 tggaaaataa attctcggta gccagtaaag ccacactttt tagcaaagcg ggtcaaagca
     8581 gcttgagaaa tatgtaattt ttgggtgact tgttgagaag ataaatcatc tgtaatcgtt
     8641 tcagcttgca aaaaatagcg agcgatttct tgctctaggt ctgtcatttc ttcaaaatgt
     8701 gaatcaatga tagttgcgat atctggtttg tccataggga aagctccttt acatgagtca
     8761 tactggaaga ctagatcagg gaatagtcac acttcattat aacacataat ataaggatag
     8821 ataaataaaa acgcatctct gttttaaaaa cgaaaaaatc gaaaaagctt ctctcttttc
     8881 cataattttc tactcaaatt gtggtacaat taagagtaag attttaagtt agaaatgaga
     8941 ctgatttgta tgagaaaatt taacagccat tcgattccga ttcggcttaa tttattgttt
     9001 tcaatcgtca ttttactctt tatgaccatt attggtcgtt tgttgtatat gcaggttttg
     9061 aacaaggatt tttacgaaaa aaagctagcc tcagctagtc agaccaagat tacaagcagt
     9121 tcagcccgtg gggaaattta tgatgctagt ggaaaacctt tggtagaaaa tacgttaaag
     9181 caggttgttt cctttacgcg tagcaataaa atgacggcta cagacttaaa agaaacagct
     9241 aaaaagttac tgacttatgt gagcatcagt tctccaaatt tgacaaaacg ccagctggcg
     9301 gattactatt tggctgatcc tgaaatctat aaaaaaacag tggaagctct cccaagcgag
     9361 aaacgcttgg attcagatgg caatcgtcta tccgaatcag aactgtataa caatgcggtc
     9421 gatagtgtcc aaacaagtca actaaactat acagaggatg aaaagaaaga aatctatctt
     9481 tttagtcagt taaatgctgt tggaaacttt gcgacaggaa ccattgctac agatcctcta
     9541 aatgattctc aggtggctgt tattgcctct atttcaaagg agatgcctgg cattagtatt
     9601 tctacttctt gggatagaaa ggttttggaa acttcccttt cttctatagt tgggagtgta
     9661 tccagtgaaa aagctggtct cccagcggaa gaagcagaag cctatcttaa aaaaggctat
     9721 tctctaaatg accgtgtagg aacctcctat ttggaaaagc aatatgaaga gaccttacaa
     9781 ggaaaacgat cggtaaaaga aatccatctg gataaatatg gcaatatgga aagcgtggat
     9841 acaattgagg aaggtagtaa gggaaacaat atcaaactga ccattgattt ggccttccaa
     9901 gatagcgtgg atgctttgct gaaaagttat ttcaattctg agctagaaaa tggtggagcc
     9961 aagtattctg aaggtgtcta tgcagtcgcc cttaacccaa aaacaggtgc ggttttgtct
    10021 atgtcaggga ttaaacatga cttgaaaacg ggagagttga cgcctgattc cttgggaacg
    10081 gtaaccaatg tctttgttcc aggttcggtt gtcaaggcgg cgaccatcag ctcaggttgg
    10141 gaaaatggag tcttgtcagg aaaccagacc ttgacagacc agtccattgt cttccaaggt
    10201 tcagctccca tcaattcttg gtatactcag gcttacggtt cattccctat cacagcggtc
    10261 caagctctgg agtattcatc aaatacctat atggtccaaa cagccttagg tcttatgggg
    10321 caaacctatc aacccaatat gtttgtcggc accagcaatc tagagtctgc tatggagaaa
    10381 ctgcgttcaa cctttggcga atatggcttg ggtactgcga caggaattga cctaccagat
    10441 gaatctactg gatttgttcc caaagagtat agctttgcta attacattac taatgccttt
    10501 gggcagtttg ataactatac gccgatgcag ttggctcagt atgtagcaac tattgcaaat
    10561 aatggtgttc gtgtggctcc tcgtattgtt gaaggcattt atggtaataa tgataaggga
    10621 ggactgggtg acttgattca gcaactgcaa ccgacagaga taaataaggt caatatatcc
    10681 gactccgata tgagcatctt gcaccaaggt ttttatcagg ttgcccatgg tactagtgga
    10741 ttgacaactg gacgtgcctt ttcaaatggt gccttggtat ccattagcgg aaaaacaggt
    10801 acagccgaaa gctatgtggc agatggtcag caagcaacca ataccaatgc ggtggcctat
    10861 gccccatctg ataatcccca aatcgctgtc gcagtggtct ttcctcataa taccaatcta
    10921 acaaatggtg taggaccttc cattgcgcgt gacattatca atctgtatca aaaataccat
    10981 ccaatgaact agaaaggaaa ttatgcttta tccaacacct attgccaagt tgattgacag
    11041 ttattctaag ttaccaggta tcgggattaa gacggctacg cgtctggcct tttatacgat
    11101 tgggatgtct gctgatgatg tcaatgaatt tgcaaaaaat ctcctttctg ctaagagaga
    11161 attgacatat tgttctattt gtggacgttt gacagacgac gatccttgtt ctatctgtac
    11221 tgatccgact cgtgaccaga caacaatttt agttcttgag gatagtagag atgtggcagc
    11281 catggaaaat atccaagaat accatggact ctatcatgtc ctgcatggcc tcatttctcc
    11341 tatgaatggt atcagtccgg acgatatcaa tctcaagagc cttatgactc gtcttatgga
    11401 tagtgaggtt tcagaagtga ttgtggcgac taatgctaca gcggatggtg aagcgacttc
    11461 catgtatctt tcacgtttgc tcaagccagc tggtatcaag gttacgcgtc tagcacgagg
    11521 tctcgctgtg ggagcggaca ttgagtatgc ggacgaagtg acactcttac gagcgattga
    11581 aaatcggaca gagttgtaag tgtaggcaaa tttacgaact cccttcattt ataaaaaatc
    11641 aaagaggctg aaaatcgttc ctatcggcct ctttttgtat agtgtgatga gtaggatcgg
    11701 gttcaagttt taaaaaacca agcaaatatg atatactaaa gagcgagtat tctagtagaa
    11761 ttaggacaaa taatatgaaa caaacgatta ttcttttata tggtggacgg agtgcggaac
    11821 gcgaagtctc tgtcctttca gctgagagtg tcatgcgtgc ggtcaattac gaccgtttca
    11881 cagtcaagac tttctttatc agtcagtcag gtgactttat caaaacacag gaatttagtc
    11941 atgctccggg gcaagaagac cgtctcatga ccaatgaaac cattgattgg gataagaaag
    12001 ttgcaccaag tgctatctac gaagaaggtg cagtggtctt tccagtcctt cacgggccaa
    12061 tgggagaaga tggctctgtt caaggattct tggaagtttt gaaaatgcct tacgttggtt
    12121 gcaacatttt gtcatcaagt cttgccatgg ataaaatcac gactaagcgt gttctggaat
    12181 ctgctggtat tgcccaagtt ccttatgtgg ctatcgttga aggcgatgat gtgactgcta
    12241 aaatcgctga agtggaagaa aaattggctt atccagtctt cactaagccg tcaaacatgg
    12301 ggtctagtgt cggtatttct aagtctgaaa accaagaaga actccgtcaa gccttaaaac
    12361 ttgccttccg atatgacagc cgtgtcttgg ttgagcaagg agtgaatgcc cgtgaaattg
    12421 aggttggcct cttgggtaac tacgatgtca agagcacgct acctggagaa gttgtcaagg
    12481 acgttgcctt ttatgactac gatgccaagt atattgataa caagattact atggatattc
    12541 ctgccaaaat cagtgatgat gtggtagctg tcatgcgtca aaatgcagaa acagccttcc
    12601 gtgccattgg tggccttggt ctatctcgtt gcgatttctt ctatacagat aagggagaga
    12661 tttttctcaa cgagctcaat accatgccag gtttcaccca gtggtctatg tacccactac
    12721 tttgggacaa tatggggatc agctacccag aactaatcga gcgtttggtt gaccttgcca
    12781 aggaaagttt tgacaagcgc gaagcgcatt tgatataaaa tgaaagagag ggtagaagcc
    12841 agaaccatca ctgcaaggtg actagagttc tcggacttca gcccttttta aaggagtaga
    12901 aatgaaatta acaatccatg aagttgccca agttgttgga gccaaaaatg atatcagtat
    12961 ctttgaggac acccagttag aaaaagctga gtttgatagt cgtttgattg gaactggaga
    13021 tttatttgtg cccctaaaag gtgtgcgtga cggtcatgac tttatcgaaa gagcttttga
    13081 aaatggtgcg gcagcaaccc tgtctgagaa agaggttgca aatcatccct acattctagt
    13141 agatgatgtt ttgactgcct ttcaacaact agctgcctac tatcttgaaa aaacagctgt
    13201 tgatgtcttt gcggttacgg gttcaaatgg caagacaacg actaaggata tgttggcgca
    13261 tttactgtca acaagataca agacctacaa aacacaaggc aattacaata atgagattgg
    13321 ccttccttac acagttctcc acatgcctga aggaacagaa aagttggtct tggagatggg
    13381 gcaggaccac ttgggagata ttcatctctt gtctgaattg gctcgtccaa aaacagccat
    13441 cgtgaccttg gttggagaag ctcatttggc ctttttcaaa gatcgttctg agattgctaa
    13501 aggaaaaatg caaattgcag acggaatggc ttcaggttcc ttgcttttag cgccggctga
    13561 ccctatcgta gaggactatt tgccaactga taaaaaggtg gttcgttttg gtcaaggagc
    13621 agagctggaa attactgact tggttgagcg caaagatagt ctgaccttca aggccaattt
    13681 cttagagcaa gtccttgatt tgccagtaac tggcaagtac aatgcgacaa atgctatgat
    13741 tgcatcctat gttgccttgc aagaaggagt ttcagaggag caaattcgtt tggccttcca
    13801 acatcttgaa ttgacgcgta accgtaccga gtggaagaaa gcagccaatg gagcagacat
    13861 cttgtcagat gtttacaatg ccaatccaac tgctatgaag ctgattttag agaccttctc
    13921 tgccattcca gccaatgaag gtggcaagaa aattgcagtg ttggcggata tgaaggaact
    13981 tggtgtccag tctgttcaac ttcataatca gatgattttg agcctttcgc cagatgtgct
    14041 tgatactgtt attttctacg gagaagatat tgctgaatta gcccaacttg ctagtcaaat
    14101 gttcccaatc ggacacgttt attacttcaa gaaaacagaa gaccaagacc aatttgaaga
    14161 cctagttaag caggtcaaag aaagccttgg ggctcatgac caaatcctgc tcaaaggctc
    14221 taactctatg aatctagcca agttggtaga aagtttagaa aatgaagaca agtgattttg
    14281 tcaagtattt gcaaagaatg attgccatta cagatactgg attaaccttt acaaaagatc
    14341 cgtttgaccg tgagcgctac gaagacttgc gagaccttct atctgaaatg ttgaatcaag
    14401 catcagacct tgattccgaa gaagtggcag aagtcttgaa gccaacttct gcttatgcga
    14461 ctcccttaat ggacgtccgt gcttggattg ttgaggacga aaagatttgt ctggttaggg
    14521 gacaaggaga ggatagttgg gctttgccag gtggctttgg tgaagtcggc tattctccaa
    14581 ctgaaaatat tctcaaggaa attgaagaag aaaccggttt taaagccaaa gttgaaagac
    14641 tgctagctgt ttttgatacc aatcgtttcc aactacagag caaacaatat gcaaagtttg
    14701 tttttgaatg taagcttctc gatggacaat tccaagaaaa tcaagaaatc gctgaccttc
    14761 aattttttgc aattgaccca ctgccgaatt tatctgaaaa acgcattacc aaggagcaaa
    14821 tcgagattct ttggcaggtt tatcaaggtc agagggagca atatcttgac taagaagatg
    14881 attatcgtat ttctaaattc atttttctta agtagcatgg tataataaaa tgcaggaaaa
    14941 ttttgaatca tgaggaagac tagatgaatt tatgggatat tttctttacg actcaggcaa
    15001 ccgagccgcc caaatttgac cttttttggt atgttagcct atttacgctc ttagccttaa
    15061 ccttttatac agcccatcgc tatcgtgaaa agaaggttta ccaacgattt ttccaaatct
    15121 tgcagactgt tcagttaatc cttctttatg gttggtactg ggtcaatcat atgccactgt
    15181 cagaaagcct acccttttac cattgccgta tggctatgtt tgtggtactc ttgcttcctg
    15241 gtcagtccaa atataaacaa tactttgcat tattgggaac atttgggaca ttagcagcct
    15301 ttgtttatcc agtgccagat gcttaccctt ttccacatat caccattcta tcctttatct
    15361 ttggtcattt agcactcttg gggaactctc tagtttatct attgagacag tataatgcgc
    15421 gattgctgga tgtgaaggga atttttctca tgacctttgc cctaaatgcc ttgatttttg
    15481 tggtcaattt ggtgacaggt ggcgattacg gatttttgac aaaaccgcca ttggttgggg
    15541 atcacggtct agtagctaat tatttacttg tttcaattgt gctggtagct actatcagtt
    15601 tgactaagaa aatcttagaa ttctttttag ctcaagaagc agaaaaaatg attgcaaagg
    15661 aagcttaaca cagagctttc ttttttgctc ttagagagtt tttacaagca gcttataaaa
    15721 taagaatttc tgaatagaca aactcaaaaa atggctggga aatttaggaa aaaagcaagc
    15781 acgattaaat tttttgtgtt ataatatttt gtgaatagct atgcctatgt ttagctatgg
    15841 aataatacga agtgcgaaac ttggaagata gagaggaagc gatgtaatgg ctagagaagg
    15901 cttttttaca ggtctagata ttggaacaag ctctgtcaag gtgcttgtgg ccgagcagag
    15961 aaatggtgaa ttaaatgtaa ttggcgtgag taatgccaaa agtaaaggtg taaaggatgg
    16021 aattattgtt gatattgatg cagcagcaac tgctatcaag tcagccattt cccaagcgga
    16081 agaaaaggca ggcatttcga ttaaatcagt aaatgtcggc ttgcctggta atcttttgca
    16141 ggtagaacca actcagggga tgattccagt aacatctgat actaaggaaa ttacggatca
    16201 agatgttgaa aatgttgtca aatcagcttt gacaaagagt atgacacctg accgtgaagt
    16261 cattaccttt attcctgaag aatttattgt ggatggtttc caagggattc gtgacccacg
    16321 tggcatgatg ggggttcgcc ttgaaatgcg tggtttgctt tatacaggac ctcgtactat
    16381 cttgcacaat ttgcgtaaga cggttgagcg tgcaggtgtt caggttgaaa atattatcat
    16441 ttcaccacta gcaatggttc agtctgtttt gaatgaaggg gaacgtgaat ttggtgctac
    16501 agtgattgat atgggggcag gtcaaacgac tgtcgctaca atccgtaatc aagaactcca
    16561 gttcacacat attctccaag aaggtggaga ttatgtaact aaagatatct ccaaggtttt
    16621 gaaaacctct cgcaaattag cggaaggctt gaaactgaat tacggggaag cctatccgcc
    16681 tcttgcaagc aaagaaacct tccaagtaga ggttattgga gaagtggaag cagtcgaagt
    16741 gacggaagcc tacttgtcag aaattatttc tgcacgaatc aagcacatcc ttgaacaaat
    16801 caagcaagaa ttagatagaa ggcgtctatt ggacctccct ggtggtattg tcttaatcgg
    16861 tgggaatgcc attttaccag gtatggttga gcttgctcag gaagtctttg gcgtccgtgt
    16921 caagctttat gttccaaatc aagttggtat ccgtaatcca gcctttgcgc atgtgattag
    16981 tttatcagaa tttgcgggtc aattaacaga agttaatctt ttggctcagg gagcgataaa
    17041 aggtgagaat gacttaagtc atcagccaat tagttttggt gggatgctgc aaaaaacagc
    17101 tcagtttgta caatcaacgc ctgttcaacc agctcctgct ccagaagtag agtcggtggc
    17161 gcctacagaa ccaatggcgg atttccaaca agcttcacaa aataaaccga aattagcaga
    17221 tcgtttccgt ggcttgatcg gaagcatgtt tgacgaataa agaggaaaaa taaattatga
    17281 cattttcatt tgatacagct gctgctcaag gggcagtgat taaagtaatt ggtgtcggtg
    17341 gaggtggtgg caatgccatc aaccgtatgg tcgacgaagg tgttacaggc gtagaattta
    17401 tcgcagcaaa cacagatgta caagcattga gtagtacaaa agctgagact gttattcagt
    17461 tgggacctaa attgactcgt ggtttgggtg caggaggtca acctgaggtt ggtcgtaaag
    17521 ccgctgaaga aagcgaagaa acactgacgg aagctattag tggtgccgat atggtcttca
    17581 tcactgctgg tatgggagga ggctctggaa ctggagctgc tcctgttatt gctcgtatcg
    17641 ccaaagattt aggtgcgctt acagttggtg ttgtaacacg tccctttggt tttgaaggaa
    17701 gtaagcgtgg acaatttgct gtagaaggaa tcaatcaact tcgtgagcat gtagacactc
    17761 tattgattat ctcaaacaac aatttgcttg aaattgttga taagaaaaca ccgcttttgg
    17821 aggctcttag cgaagcggat aacgttcttc gtcaaggtgt tcaagggatt accgatttga
    17881 ttaccaatcc aggattgatt aaccttgact ttgccgatgt gaaaacggta atggcaaaca
    17941 aagggaatgc tcttatgggt attggtatcg gtagtggaga agaacgtgtg gtagaagcgg
    18001 cacgtaaggc aatctattca ccacttcttg aaacaactat tgacggtgct gaggatgtta
    18061 tcgtcaacgt tactggtggt cttgacttaa ccttgattga ggcagaagag gcttcacaaa
    18121 ttgtgaacca ggcagcaggt caaggagtga acatctggct cggtacttca attgatgaaa
    18181 gtatgcgtga tgaaattcgt gtaacagttg ttgcaacggg tgttcgtcaa gaccgcgtag
    18241 aaaaggttgt ggctccacaa gctagatctg ctactaacta ccgtgagaca gtgaaaccag
    18301 ctcattcaca tggctttgat cgtcattttg atatggcaga aacagttgaa ttgccaaaac
    18361 aaaatccacg tcgtttggaa ccaactcagg catctgcttt tggtgattgg gatcttcgcc
    18421 gtgaatcgat tgttcgtaca acagattcag tcgtttctcc agtcgagcgc tttgaagccc
    18481 caatttcaca agatgaagat gaattggata cacctccatt tttcaaaaat cgttaagtaa
    18541 atgaatgtaa aagaaaatac agaacttgtt tttcgagaag ttgcagaggc tagtctgagt
    18601 gctcatcgag agagtggttc ggtctctgtc attgcagtta ccaagtatgt agatgtaccg
    18661 acagcggaag ccttgcttcc gctaggtgtt catcatatcg gtgaaaatcg tgtagataag
    18721 tttctggaaa aatatgaagc tttaaaagat cgagatgtga cttggcattt gattggtacc
    18781 ttgcaaagac gtaaggtgaa agatgtcatt caatacgttg attatttcca tgcattggac
    18841 tcagtaaagc tagcagggga aattcaaaaa agaagtgacc gagtcatcaa gtgtttcctt
    18901 caagtaaata tttctaaaga agaaagcaaa cacggttttt cgagagagga actgctggaa
    18961 atcttgccag agttagccag actagataag attgaatatg ttggtttaat gacgatggca
    19021 ccttttgagg ctagcagtga gcagttgaaa gagattttca aggcgaccca agatttacaa
    19081 agagaaattc aagagaaaca aattccaaat atgcctatga ccgagttaag tatgggaatg
    19141 agtcgtgatt ataaagaagc gattcaattc ggttccactt ttgttcgtat aggtacatca
    19201 ttttttaagt aggagagaac catgtcttta aaagatagat tcgatagatt tatagattat
    19261 tttacggagg atgaggattc aagtctccct tatgaaaaaa gagatgagcc tgtgtttact
    19321 ccagtaaatt cttcacagga accggctctc ccaatgaatc aaccttcaca gtcggctggt
    19381 acaaaagaga acaatatcac cagacttcat gcaagacaac aggaattggc aaatcagagt
    19441 cagcgtgcaa cggataaggt cattatagat gttcgttatc ctagaaaata tgaggatgca
    19501 acagaaattg ttgatttatt ggcaggaaac gaaagtatct tgattgattt tcagtatatg
    19561 acagaggtgc aggctcgtcg ttgtttggac tatttggatg gagcttgtca tgttttagct
    19621 ggaaatttga aaaaggtagc ttctaccatg tatttgttga caccagtgaa tgttattgta
    19681 aatgttgaag atatccgttt accagatgaa gatcaacagg gtgagttcgg ttttgatatg
    19741 aagcgaaata gagtacgata atgatttttt taattcgtat gatttataat gcagtggata
    19801 tttactccct gattttggta gccttcgctg tcatgtcttg gtttccaggt gcctacgaat
    19861 ccagtttagg tcgttggatt gtagcgttgg tgaaaccagt gcttgctccc ttgcaacgcc
    19921 tgcctttaca gatagcgggt cttgatttat ctgtttgggt cgcgattgtt ttggttcgat
    19981 ttttaggaga aaacctagtg cgttttctgg cgatgatagg atgaataaag ggatttatca
    20041 gcatttctcc atagaagatc gtccatttct tgacaaggga atggaatgga taaagaaggt
    20101 agaagatagc tatgctcctt ttttaactcc ttttatcaat cctcatcagg agaagctatt
    20161 aaagattttg gccaaaacct atggtcttgc ttgtagcagt agtggggaat tcgtctcgag
    20221 tgagtatgtt cgagttttat tatacccaga ttatttccaa ccagagtttt cagattttga
    20281 aatatctctc caggaaattg tgtattccaa taaatttgaa catttaacgc atgctaagat
    20341 tttagggaca gtcatcaatc aattagggat tgaacggaaa ctttttggag atatcctagt
    20401 agatgaagaa cgggcgcaga ttatgattaa tcagcagttt cttcttctct ttcaagatgg
    20461 actaaagaaa attggtcgta tacctgtttc gctggaggaa cgtcctttca ccgagaaaat
    20521 agataagcta gaacagtatc gagaactgga tttatctgtg tctagttttc gattagatgt
    20581 tctttgttca agttggagac ttgattagtg tgagaaaatt tggtcgcttg agattacttc
    20641 aagataaggg acaaacgaaa aaagagaaga aaaaaataac cgtccagtta ttattaagta
    20701 agtgaggaat agaatgccaa ttacatcatt agaaataaag gacaagactt ttggaactcg
    20761 attcagaggt tttgatccag aagaagtcga tgaattttta gatattgtgg ttcgtgatta
    20821 cgaagatctt gtgcgtgcga atcatgataa aaatttgcgt attaagagtt tagaagagcg
    20881 tttgtcttac tttgatgaaa taaaagattc attgagccag tctgtattga ttgctcagga
    20941 tacagctgag agagtgaaac aggcggcgca tgaacgttca aacaatatca ttcatcaagc
    21001 agagcaagat gcgcaacgct tgttggaaga agctaaatat aaggcaaacg agattcttcg
    21061 tcaagcaact gataatgcta agaaagtcgc tgttgaaaca gaagaattga agaacaagag
    21121 ccgtgtcttc caccaacgtc tcaaatctac aattgagagt cagttggcta ttgttgaatc
    21181 ttcagattgg gaagatattc tccgtccaac agctacttat cttcaaacca gtgatgaagc
    21241 ctttaaagaa gtggttagcg aagtacttgg agaaccgatt ccagctccaa ttgaagaaga
    21301 accaattgat atgacacgtc agttctctca agcagaaatg gaagaattac aagctcgtat
    21361 tgaggtagcc gataaagaat tgtctgaatt tgaagctcag attaaacagg aagtggaaac
    21421 tccaactcct gtagtgagtc ctcaagttga agaagagcct ctgctcatcc agttggccca
    21481 atgtatgaag aaccagaagt agctccagtg catccgacag gtccaacacc agctacagaa
    21541 actgttgatt cagcaccggg atttgaagca ccgcaagaat ctgttacaat tttataagaa
    21601 atattctgag aacaatatct tatccttata ttcccagcga gcaggagatg gtgtgagtcc
    21661 tgcattccct atcgataaga ttatcctctc aaactatcaa gtctgaatct agtaagattt
    21721 gacgttcccc acgttacggg ataagaggga gaaagactaa aactttttcc gaataaaggt
    21781 ggtaccacga ttttcgtcct ttttggaagt cgtggttttt aatttgttat tatttataaa
    21841 ggagatacca tgaaactcaa agacaccctt aatcttggga aaactgaatt cccaatgcgt
    21901 gcaggccttc ctaccaaaga gccagtttgg caaaaggaat gggaagatgc aaaactttat
    21961 caacgtcgtc aagaattgaa ccaaggaaaa cctcatttca ccttgcatga tggccctcca
    22021 tacgctaacg gaaatatcca cgttggacat gctatgaaca agatttcaaa agatatcatt
    22081 gttcgttcta agtctatgtc aggattttac gcaccattta ttcctggttg ggatactcat
    22141 ggtctgccaa tcgagcaagt cttgtcaaaa caaggtgtca aacgtaaaga aatggacttg
    22201 gttgagtact tgaaactttg ccgtgagtac gctctttctc aagtagataa acaacgtgaa
    22261 gattttaaac gtttgggtgt ttctggtgac tgggaaaatc catatgtgac cttgactcct
    22321 gactatgaag cagctcaaat tcgtgtattt ggtgagatgg ctaataaggg ttatatctac
    22381 cgtggtgcta agccagttta ctggtcatgg tcatctgagt cagcccttgc tgaagcagag
    22441 attgaatacc atgacttggt ttcaacttcc ctttactatg ccaacaaggt aaaagatggc
    22501 aaaggagttc tagatacaga tacttatatc gttgtctgga caacgactcc atttactatc
    22561 acagcctctc gtggtttgac ggttggtgca gatattgatt acgttttggt tcaacctgct
    22621 ggtgaagctc gtaagtttgt cgttgctgct gaattattga ctagcttgtc tgagaaattt
    22681 ggctgggctg atgttcaagt tttggaaact taccgtggcc aagaactcaa ccacatcgta
    22741 acagaacacc catgggatac agctgtagaa gagttggtaa ttcttggtga ccacgttacg
    22801 actgactctg gtacaggtat tgtccataca gcccctggtt ttggtgagga cgattacaat
    22861 gttggtattg ctaataatct tgaagtcgca gtgactgttg atgaacgtgg tatcatgatg
    22921 aagaatgctg gtcctgaatt tgaaggtcaa ttctatgaaa aggtagttcc aactgttatt
    22981 gaaaaacttg gtaacctcct tcttgcccaa gaagaaatct ctcactcata tccatttgac
    23041 tggcgtacta agaaaccaat catctggcgt gcagttccac aatggtttgc ctcagtttct
    23101 aaattccgtc aagaaatctt ggacgaaatt gaaaaagtga aattccactc agaatggggt
    23161 aaagtccgtc tttacaatat gatccgtgac cgtggtgact gggttatctc tcgtcaacgt
    23221 gcttggggtg ttccacttcc tatcttctac gctgaagatg gtacagctat catggtagct
    23281 gaaactattg aacacgtagc tcaacttttt gaagaacatg gttcaagcat ttggtgggaa
    23341 cgtgatgcca aagacctctt gccagaagga tttactcatc caggttcacc aaacggcgag
    23401 ttcaaaaaag aaactgatat catggacgtt tggtttgact caggttcatc atggaatgga
    23461 gtggtggtaa accgtcctga attgacttac ccagccgacc tttacctaga aggttctgac
    23521 caataccgtg gttggtttaa ctcatcactt atcacatctg ttgccaacca tggcgtagca
    23581 ccttacaaac aaatcttgtc acaaggtttt gcccttgatg gtaaaggtga gaagatgtct
    23641 aaatctcttg gaaataccat tgctccaagc gatgttgaaa aacaattcgg tgctgaaatc
    23701 ttgcgtctct gggtaacaag tgttgactca agcaatgacg tgcgtatctc tatggatatc
    23761 ttgagccaag tttctgaaac ttaccgtaag attcgtaaca ctcttcgttt cttgattgcc
    23821 aatacatctg actttaaccc agctcaagat acagtcgctt acgatgagct tcgttcagtt
    23881 gataagtaca tgacgattcg ctttaaccag cttgtcaaga ccattcgtga tgcttacgca
    23941 aactttgaat tcttgacaat ctacaaggcc ttggtgaact ttatcaacgt tgacttgtca
    24001 gccttctacc ttgattttgc caaagatgtt gtttacattg aaggtgccaa atcactggaa
    24061 cgccgtcaaa tgcagactgt cttctatgac attcttgtca aaatcaccaa actcttgact
    24121 ccaatccttc ctcacactgc ggaagaaatc tggtcatatc ttgagtttga agccgaagac
    24181 ttcgtccaat tgtcagaatt accagaagtt caaacttttg ctaaccaaga agaaatcttg
    24241 gatacatggg cagccttcat ggacttccgt ggacaagcac aaaaagcctt ggaagaagct
    24301 cgtaatgcaa aagttatcgg taaatcactt gaagcacact tgacagttta tccaaatgaa
    24361 gttgtgaaaa ctctactcga agcagtaaac agcaatgtag ctcaactttt gatcgtgtct
    24421 gagttgacca tcgcagaaga accagctccg gaagctgccc ttagcttcga agatgtagtc
    24481 ttcacagttg aacgcgctgc aggtgaagta tgtgaccgtt gccgtcgtat tgacccaaca
    24541 acagcagaac gtagctacca cgcagtcatc tgtgaccact gtgcaagtat cgtagaagaa
    24601 aactttgcag atgcagtcgc agaaggattt gaagagaaat aagattgaaa agtctaggta
    24661 aaactcaatt tgagaagaaa agacaactaa ttttatagtc tattaaacgc attgtatcac
    24721 gtttttgaac acctgatatg atgcgttttt tatttatttt aaaaatttgc gaggtatgac
    24781 tttttatact caacaagaat caaagagaaa cttagcaagc taacagtagt aatataaaat
    24841 aggaatttga tattagggat aagattggta aatagtgtaa tatttttaca acaataaatt
    24901 tatatagtta tttctggttt ctgaaaagta ttatattata ttttatttca tattatacaa
    24961 atttttattt tataatatca gaaaatactt tttttaaaaa gcaaatatga tacaatttta
    25021 tttgaaaaaa aataaaaaag gagattttat tatgaaatca agtggtatcg tcggtcttgt
    25081 gggaggaatt ttacttctta tttgtccttt tgtcttgttg ggaacagcgg taaatacagc
    25141 tgctacaact cttaatggag gagctactgc aggggctttt tcaggtgttg ccttactctt
    25201 gaatgccttg aagattgcaa atcttgttct tggtatcatt gctattgttt actataaagg
    25261 agataagcat gtaggtgcag ctccgtctgt actaatgatt gtttctggtg aagttagtct
    25321 cattccattc ttaggatggg ttggggggat tcttgctatt atcggaggat ctctattcct
    25381 tgcaacattg aagaaattca aatcagaaga ataaaaggta ttttagcatg aaaagaacaa
    25441 aaaagtttat cggtatagga gtagctctat tatctctttc tcttctagtt gcatgtggaa
    25501 cataaagttc aaagaatact tcaacaagta atgatgagaa gacagtagca acatccaata
    25561 gttcaaaaga aacaatcact ttcgatacac cggttgtaac agacgatgcg attgaatcaa
    25621 tacgcactta tgcagattat atagatcttt ataaaaatat ttttgatgat tattttacta
    25681 aagctgagga aggtttcaaa ggcacaacta tggaaaataa tgactcgttt actaaactaa
    25741 aagagtcaac tcaaaaatta ttcgatgcgc agaaaaaaag gttaaataat gaagatagaa
    25801 tagaaacaac caaaaacaat gtgattgcca aacattgtca aacagtcctt tcctttttgg
    25861 ttttgactag cttttttgtg aaaaattgtg taaaatagaa tagataaacg aggggaaacc
    25921 tcggaaaatt taaaggagaa tccatctaat ggtaaaattg gtttttgctc gccacggtga
    25981 gtctgaatgg aacaaagcta accttttcac tggttgggct gatgttgatt tgtctgaaaa
    26041 aggtacacaa caagcgattg acgctggtaa attgatcaaa gaagctggta tcgaatttga
    26101 ccaagcttac acttcagtat tgaaacgtgc tatcaaaaca actaacttgg ctcttgaagc
    26161 ttctgaccaa ttgtgggttc cagttgaaaa atcatggcgc ttgaacgaac gtcactacgg
    26221 tggtttgact ggtaaaaaca aagctgaagc tgctgaacaa tttggtgatg agcaagttca
    26281 catctggcgt cgttcatacg atgtattgcc tccaaatatg gaccgtgatg atgagcactc
    26341 agctcacaca gaccgtcgtt atgcttcact tgacgactca gtcattccag atgctgaaaa
    26401 cttgaaagtg actttggaac gtgctcttcc attctgggaa gataaaatcg ctccagctct
    26461 taaagatggt aaaaacgtat tcgtaggagc tcacggtaac tcaatccgtg cccttgtaaa
    26521 acacatcaaa ggtttgtcag atgatgagat catggacgtg gaaatcccta acttcccacc
    26581 attggtattc gaattcgacg aaaaattgaa cgttgtttct gaatactacc ttggaaaata
    26641 aaaaattgta agcctaggat tgatttctag gctttttatg ttagtatgga agtatgataa
    26701 ggaataaaaa acaagattat gtactggcct acaagcaacc agcttcaacc acttacatgg
    26761 gttgggaaga agaagcttta ccgataggca atggttcttt aggagcaaaa gtatttggcc
    26821 ttataggggc tgaacggatt caatttaatg aaaaaagtct ctggtctgga ggtccacttc
    26881 ctgatagttc agattatcag ggtggaaatc ttcaggatca gtatgttttt ttagctgaga
    26941 ttcggcaggc tttggagaag agagattaca atctggctaa ggaactggct gagcagcacc
    27001 taattgggcc aaaaacgagt caatatggga cctatctgtc ttttggggat attcacattg
    27061 agttcagcca gcaaggtacg actttgtctc aggtgacgga ctatcagaga cagctgaata
    27121 ttagtaaggc acttgcgacg acttcttatg tctataaggg aacgcgattt gaacgtaaag
    27181 cttttgcgag ttttccagat gatctcttga ttcaatgttt tactaaggaa gggttggaaa
    27241 ctctagattt tactatagaa ctatccttga cctgtgattt ggcttctgat ggaaagtatg
    27301 agcaggaaaa atctgattac aaggagtgta agttggatat tactgattct catatcttga
    27361 tgaagggaag agttaaggat aatgatctgc ggtttgctag ttatctagct tgggaaacgg
    27421 atggagatat tagagtttgg tcagataggg ttcagatatc aggagccagt tatgccaatc
    27481 tcttcttggc cgctaagacg gattttgccc aaaatcctgc tagcaattat cgcaagaaac
    27541 tagatttaga gcaacaggtg atagacttgg tggacacagc taaagaaaag ggctataccc
    27601 aattgaaatc aaggcatatc gaggactacc aagccttatt ccagcgtgtt caattggatt
    27661 tggaagctga tgttgacgca tccactacag atgatttgtt aaaaaattat aagccacaag
    27721 aagggcaggc tttggaggag ctgttcttcc agtatggacg gtatttattg attagttcgt
    27781 ccagagactg cccagatgct ctaccagcta acctacaggg agtctggaat gcggtcgaca
    27841 atcctccttg gaattcggac tatcacttaa atgtcaatct gcagatgaat tattggccag
    27901 cctatgttac caatctccta gagacggtct ttccagtcat caactatgta gatgatttgc
    27961 gtgtctatgg tcgtctagcg gctgtaaagt atgcaggaat cgtctctcaa aaaggtgagg
    28021 aaaatggttg gttggttcat actcaagcga ctccctttgg ttggacggca cctggttggg
    28081 attactattg gggttggtca ccagctgcca atgcgtggat gatgcaaacc gtttatgaag
    28141 cctattcatt ttatagggac caagactatc tcagggagaa aatttatccc atgttgaggg
    28201 aaacggttcg tttttggaat gcctttttac ataaggatca gcaggcgcag cgttgggtct
    28261 cttctccgtc ttattcccca gaacatgggc cgatttcgat tggcaatacc tatgaccaat
    28321 ctctgatttg gcagttattt catgatttta ttcaggctgc tcaggaattg ggactggatg
    28381 aggacttgtt gactgaggtt aaggagaagt ctgatttact aaatcctttg caaatcactc
    28441 aatctggtcg aatcagggag tggtatgagg aggaagagca gtattttcaa aatgagaaag
    28501 tggaggccca gcatcggcac gcttcccatc tagtgggact ctattctggc aatctcttta
    28561 gctacaaggg acaagagtat attgaagcgg cgcgtgctat cctcaatgat cgtggagatg
    28621 gcggcacagg ctggtccaag gctaataaga tcaatctctg ggcgcgtttg ggagatggca
    28681 atcgagccca taaattattg gcagagcagt taaagacatc caccttgcca aatctttggt
    28741 gtagccatcc tccttttcag atagatggta attttggtgc tactagtggc atggcagaaa
    28801 tgttactcca gtctcatgca gcttatctgg tacctctagc tgccctacct gatgcttggt
    28861 caacaggttc tgtttcaggc ttaatggcac gtggacattt tgaagtgagc atgagctggg
    28921 aagataaaaa actcttacag ttgaccattt tatcaaggag tggaggagat ttgcgagttt
    28981 cttatccaga tattgagaag agtgtgatta aaatgaatca agaaaaaata aaagcgaaat
    29041 gcatggggaa agattgtatt tcggtggcaa cagcagaagg tgatcttgtt caattttatt
    29101 tttaagaaga tgttataagg cagtaatttg aaacttcctt ttaataagga tttgagaata
    29161 taggcagttt ccaactagtt gaaaaagcgt tataatgata ataggaagta atactcaatg
    29221 aaaatcaaag agcacaaact aggaagctag ccgcaggttg ctcaaaacag tgttttgagg
    29281 ttgtagatgg aagctgacgt ggtttgaaga gagattttcg aggagtataa tttgtttgat
    29341 agagggtggg tctgatggct tatattgaga tgaaacactg ttacaagcgt tatcaggttg
    29401 gggacacgga gattgtggcc aatcgtgatg tgaattttga gattgaaaag ggggagctgg
    29461 ttattatcct tggtgcttca ggtgcaggca agtcaacagt tcttaacctt cttgggggaa
    29521 tggataccaa tgatgaaggg gaaatctgga ttgatggtgt taatattgcg gattatagtt
    29581 cccaccagcg taccaattac cgtagaaatg atgtggggtt tgtttttcag ttttataatc
    29641 tagtttctaa tctgacagct aaggaaaatg tggaactggc ttctgaaatt gtgacagatg
    29701 ccttgaatcc tgatcaggtc ttgacagatg taggtctggc tcatcgtctc aataactttc
    29761 cagcccagct ttctggaggg gagcaacagc gagtctccat tgcacgcgcg gtagccaaaa
    29821 atcctaaaat tctcctttgt gatgaaccga ctggagcctt ggattatcag acgggcaagc
    29881 aggttttgaa aattctccaa gacatgtctc gtcaaaaggg agcgacggtg atcatcgtga
    29941 ctcataatgg agctttggcg cccattgctg atcgcgtgat tcaaatgcac gatgccagtg
    30001 tcaaggatgt ggtgctcaac cagcatcctc aggatattga cagtttggag tactagcatg
    30061 atcaagcgaa aaacttattg gaaggactta attcagtcct tcacaggctc caaggggcgt
    30121 tttttatcca tcttgatcct gatgatgttg ggatctctag ccttagtagg cctcaaagta
    30181 accagtccca acatggaggc gacagctaat gcttatttaa caactgctca aaccttggat
    30241 ttggcagtca tgtctaacta tggcttggat caagcagacc aagaagaact aaaacagacg
    30301 gagggcgcag aggtcgagtt tggctatttg acagatgtga ctatggataa tgggcaggat
    30361 gccattcggc tgtactccaa accagagcga atttcaacct ttcagctaag aaagggacga
    30421 cttcctcagt cagacaagga aatcgctttg gccactcatt tgcaaggcca atacagcgtg
    30481 ggacaggaga ttagttttaa agaaaaagaa gagggtcatt cctctttaaa agaccatact
    30541 tataccatta ctggttttgt ggattcggct gaaatcctct cccagcgaga tatgggctac
    30601 gcaggaagtg gaagtgggac tctgacagcc tatggggtga ttttacctag tcagtttgat
    30661 cagaaagtct acaatatagc tcgtttgaaa tatcaagatt tagcaggttt aaatgccttt
    30721 tcatcagctt atgaagaaaa atccaagcaa catcaggaag accttgaaca aactttatca
    30781 gataatggca aggtacgtct gcaacttttg aaaaaagaag gacaagagtc tctagacaag
    30841 gggcaagaga cccttgacaa ggctcagact aatttgcagg aaggcaagcg tcgtttagca
    30901 gctgctcaag ctcgtataca ggctcaagaa agtcaactag ccttgtttcc tcaagttcag
    30961 agagagcagg ctagtgctca acttacccaa gccaagcagg aattgggcaa ggaagaggat
    31021 aaactaaagc aagctgaaca aaatctagcc caagaaaagg aaaaattaga aaaacatcag
    31081 caagtcttgg acgatttggc ggagccaagg tatcaggtct ataatcgtca gaccatgcca
    31141 ggtggtcagg gctatcttat gtatagcaat gcttcatcca gtattcgagc agtgggcaat
    31201 atctttcctg tggtacttta tgccgtagca tccatggtga cctttacgac catgactcgc
    31261 tttgtagacg aagagcgaac tcatgcaggg atttttaagg ccttgggtta ccgtagtaag
    31321 gatattatca ccaagtttct cctttatgga ctagtagctg ggactgtcgg aacggctcta
    31381 ggtagtatac ttggtcatta tttgctagcc agtgtaattt caagtgtcat tacaaaaggc
    31441 atggtggtgg gagaaaccca gattcagttc tattggacct atagcttact agctcttgtc
    31501 ttgagctggt tggcgagtgt gttaccagcc tatctggtgg cttggaggga acttcatgcc
    31561 gaagcagccc agcttctact tcctaaacct cctgtcaaag gagctaaaat cttattggag
    31621 cgtatcggtt ttatctggcg tcgtctcagt tttactcata aggtaacagc ccgcaacatc
    31681 tttcgttata agcagagaat gttgatgaca atctttggtg tggcaggttc tgtagctctg
    31741 ctctttgcag gtttgggaat ccaatcttct gtagcaggag ttccgtctaa acagtttcaa
    31801 caaatccaac agtatcagat gcttgtctct gaaaatccta gtgcgaccaa tcaggacaag
    31861 gtagagctag cagaagtgtt gaaagggcag gagatactag cctaccagaa aatctattct
    31921 aaaacgctag acaaggattt caaaggcaag gctggtcttc aaaacattac tcttatgatg
    31981 atagagaagg aagatttgac tccctttatc catcttcaac atcatcagca ggagctgaca
    32041 ttaaaagatg gcatcgttat tacagctaaa ctcgcccagc tggcaggtgt caaggttggg
    32101 cagactttag aaattgaagg taaggaacta aaggtcgctg ctattactga gaactacgtt
    32161 ggtcacttta tttatatgag tcaggctagc tatgagcaac tttacggaca gctaccccaa
    32221 gccaacactt atctggtctc attaagggat accagtgcaa ctagtatcga aagtcaggcg
    32281 ggcttgctta tgaatcaatc tgcggtgtcc agcgttgtcc aaaatgcttc agccattcga
    32341 ctctatcgct agctcactca atcagaccat gaccatcttg gtcatcgtat cagttctatt
    32401 agctattgtc atcctttaca atctgaccaa tatcaacgta gctgagagaa tccgtgaact
    32461 ctccactatc aaggttctcg gttttcataa taatgaagtc accctctaca tttaccgtga
    32521 gacgattgtg ctgtcccttg tgggaatcgt acttggtctg gtagctggtt tctatttaca
    32581 ccaatttttg attcaaatga tttcgcctgc gactattctc ttttatccgc aggtaggctg
    32641 ggaagtctat gtaatcccag tggcaacagt aagcatcatt ttgaccttgc ttggtttctt
    32701 cgtcaattat tatctgagaa aggttgatat gttagaagcc ctgaaatctg tagagtaagg
    32761 tagttatttt tagctgattg aacttctatt tactaatatt caaaaatcct ctgtcacaaa
    32821 gagcagggag ctctttgtga cagaggattt tttctatagg gctttagcag ctgcaattgc
    32881 ggcttcgaag tttggctcag aattgatatt atccacgtat tcaacgtagc gaatcgtatt
    32941 gtcagtatcg aggacaaaga ctgcgcgtgc taataggtgc cattcgttga tcaagagggc
    33001 ataatcgcgc ccgaaagaat ggtcaaagta gtctgaaagc ataatggcat tgtcaaggcc
    33061 ttcagcaccg caccaacgtt tttgagcaaa aggtaggtcc attgaaacag tcaatacgac
    33121 cgtgttgtcc agtccagcca attcttcatt aaaacgacgt gtttgagttg agcagatgcc
    33181 tgtatcgata gaaggaacga cactcaagac ttttttcttg ccatcaaaat cagccagaga
    33241 ttttttagaa agatctgttg tagtaagaga aaaatcaagc gccttgtcgc cgacttgtag
    33301 ttgtttacct gtaaagctca caggatttcc gagaaaagtt accataggat actccaatct
    33361 tttttcttcc attgtatctg aaacagtcag aattttccaa tgatttgacc ggaaatgtgg
    33421 gcatagaaaa aacgccagct cacatgagaa tgacgttttt cagaggctta ttttgccaat
    33481 ccttcagcaa tcttgtcaag gttgtatttc atcatgctgt agtagctgtc gccttcttta
    33541 ccttgttctg cgatagagtc agtaaagatt tgtgcgtaga ttgggatgtt tgtgtcttga
    33601 gaaacagttt tcattggacg gtcatccaca cttgattcta caaagagtga tggaactttt
    33661 gtttggcgaa gtttttcaac caaggtcttg atttgttcag gagttccttc ttcttcagta
    33721 ttgatttccc agatgtaagc acttgggaca ccataggctt tagagaagta tttgaatgct
    33781 ccttcgctgg ttacaatgag tttcttttca gcagggatct tattaaattt atccttactt
    33841 tctttatcaa gtttgtctaa cttatcagta tattctttga gatttttttc atagaattct
    33901 ttattgttag ggtctttggc gctcaattgt ttggcgatat ttttagcaaa aataataccg
    33961 ttttcaaggt taagccaagc gtgtgggtct tcttttcctt tttcattttg accttcaagg
    34021 tagataacat caacgccgtc gctgactgcg aagtagtctt tgttttcagt tttcttggca
    34081 ttttctacca attttgtaaa ccaagcattg ccacctgttt caaggttgat accgttatag
    34141 aaaatcaaat cagcctcaga agttttctta acgtcttcag gaagtggttc gtattcgtgt
    34201 gggtcttgcc caatcggaac gatactatga aggtcaattt tgtcaccagc aatattttta
    34261 gtaatatcag cgatgattga gtttgtagca acaactttta gtttttgacc agaagttgta
    34321 tctttttttc cgctagcaca tgctacaaga atgattgcag aaagaaagag aacgagtaat
    34381 gtacctaatt ttttcattag atcctccaaa ttattagggc tttgcccctt attttaacaa
    34441 atgtttattt ttcagtttca aatatcgttg tttgggagcg ataaagaagc taatgagaaa
    34501 gaaactagca gctgtaagca cgatactaga acctgccgca acattaaaac tatagccaat
    34561 aaagagtccc aaaactgaag cagtagctcc gaaggttgag gaaaggaaaa tcatgctttt
    34621 cagactatta gcatacagat aagcagttgc agctggggta atcagcatgg ctacaatcag
    34681 gatagttccg acactttgca tggctgtcac agacacgaga gtcaggagta ccatgagaag
    34741 gtagtgatag aaattgacag gcattcccat ggctttagcc aagagttcat caaaggaagt
    34801 tatcaagagt tgcttgaaga aaatccagat taacaagagg atggctgccc ccacacccat
    34861 agtaataaac atatccgtat cttggacggc caggatatta ccaaaaagga tatggaaaag
    34921 gtcagttgaa cttttagcga caccaatcaa gatgataccg agggctaaga aagaagaaaa
    34981 ggtaatgccg atggcggtat cgcttttgat aatcgagttt cctttgatgt aggtaatgat
    35041 gatggcagct agcaatccaa agacaatggc tccgataaag aagtcaaggc ccaagatgaa
    35101 ggagagggct acacctggta agacagcatg tgaaatggca tctcccatga gtgacatccc
    35161 gcgtagaata atgaaacatc ccacagctcc agctacaatc ccgacgacaa tagctgttat
    35221 caaggcattt tgtaggaaat ggaatttttg caatccatcg ataaattctg caatcatagg
    35281 tcacctccat tgaaaaagag ttgattaccg taagcttctt ttagattggt ttcggtaaaa
    35341 gtttcttttg ttggaccaaa ggcaatcact tctcgattga caagtaagac ttgatcgaag
    35401 tagtggggaa tcttgctgag gtcgtggtga acgatgagaa ccgtcttccc agcttttttc
    35461 aaatctctca gcgtattcat gatgatttcc tcactgacag agtcaatccc agcaaagggt
    35521 tcatccaaga ggatatagtc ggcttcctgc accaaacatc tggcaatcaa aacccgctgg
    35581 aattgacctc cagacagttg actaatttga cgttcagcgt agtcagctag gccgacgatt
    35641 tcaagggcct cttgcacttt cttccaatgt ttagccttta aacttcgaaa gagaggaata
    35701 gagggaaata gtcctaacga gacgcattcc ttgaccttga tgggaaagtt gtagtcgata
    35761 ttgatttttt gttcgacata ggcaattcgg tgtaaggatt ttttaacttc cttgtcatcg
    35821 agaaatgcct gaccttgatg tgggataatt cccagcatac cttttaatag tgttgatttc
    35881 ccagcgccgt ttggaccaat gatgccggta attgttggtc catggagcac tagtgaaata
    35941 tccttaagtg ccaacgtttc tttgtaggag acactgaggt tttcgatacg tatcataaac
    36001 ttgtattcct cctgtctctt aatatacatt aaaaaaaaaa ttaagtcaag ttaatttttg
    36061 aaaaaattaa aataataact gaaaaataga
//
LOCUS       DAVBIC010000019        34466 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.019, whole genome shotgun sequence.
ACCESSION   DAVBIC010000019 DAVBIC010000000
VERSION     DAVBIC010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34466)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34466)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34466
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.019"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            143..361
                     /gene="infA"
                     /locus_tag="VQ664_000893"
     CDS             143..361
                     /gene="infA"
                     /locus_tag="VQ664_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HET2789078.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            386..502
                     /gene="rpmJ"
                     /locus_tag="VQ664_000894"
     CDS             386..502
                     /gene="rpmJ"
                     /locus_tag="VQ664_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HET2789079.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            520..885
                     /gene="rpsM"
                     /locus_tag="VQ664_000895"
     CDS             520..885
                     /gene="rpsM"
                     /locus_tag="VQ664_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HET2789080.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            903..1286
                     /gene="rpsK"
                     /locus_tag="VQ664_000896"
     CDS             903..1286
                     /gene="rpsK"
                     /locus_tag="VQ664_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HET2789081.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            1329..2264
                     /locus_tag="VQ664_000897"
     CDS             1329..2264
                     /locus_tag="VQ664_000897"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HET2789082.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            2276..2662
                     /gene="rplQ"
                     /locus_tag="VQ664_000898"
     CDS             2276..2662
                     /gene="rplQ"
                     /locus_tag="VQ664_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HET2789083.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            2927..3193
                     /locus_tag="VQ664_000899"
     CDS             2927..3193
                     /locus_tag="VQ664_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HET2789084.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            3203..4540
                     /locus_tag="VQ664_000900"
     CDS             3203..4540
                     /locus_tag="VQ664_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HET2789085.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPDINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALTETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGAAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     IGDSVARVLEEMGLETVGTHGTTVALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGREGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKN"
     gene            4784..5476
                     /locus_tag="VQ664_000901"
     CDS             4784..5476
                     /locus_tag="VQ664_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HET2789086.1"
                     /translation="MVKVRLYLVRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEMIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGCEKMEEGSI"
     gene            complement(5579..7224)
                     /locus_tag="VQ664_000902"
                     /pseudo
     CDS             complement(5579..7224)
                     /locus_tag="VQ664_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
     gene            complement(7214..7519)
                     /locus_tag="VQ664_000903"
                     /pseudo
     CDS             complement(7214..7519)
                     /locus_tag="VQ664_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809465.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TOBE domain-containing protein"
     gene            complement(7646..8305)
                     /locus_tag="VQ664_000904"
     CDS             complement(7646..8305)
                     /locus_tag="VQ664_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2789087.1"
                     /translation="MSEIEIINAKKIYHDVPVIENLNITIPKGSLFTLLGASGCGKTT
                     LLRMIAGFNSIEGGEFYFDDTKINNMEPSKRNIGMVFQNYAIFPHLTVRDNVAFGLMQ
                     KKVPKEELIQQTNKYLELMQIAQYADRKPDKLSGGQQQRVTLACALAVNPSVLLMDEP
                     LSNLEAKLRLDMRQAIREIQHEVGITTVYVTHDQEEAMAISDQIAVMKDGVIQQIGRP
                     K"
     gene            complement(8318..9439)
                     /locus_tag="VQ664_000905"
                     /pseudo
     CDS             complement(8318..9439)
                     /locus_tag="VQ664_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931989.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
     gene            complement(10027..10803)
                     /locus_tag="VQ664_000906"
     CDS             complement(10027..10803)
                     /locus_tag="VQ664_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HET2789088.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGINALHPEDLIDYQKVFLNHHINCYF"
     gene            10925..11671
                     /locus_tag="VQ664_000907"
     CDS             10925..11671
                     /locus_tag="VQ664_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET2789089.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     HQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            11684..12664
                     /locus_tag="VQ664_000908"
     CDS             11684..12664
                     /locus_tag="VQ664_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HET2789090.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNAGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            12859..13179
                     /locus_tag="VQ664_000909"
     CDS             12859..13179
                     /locus_tag="VQ664_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET2789091.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            13225..13533
                     /locus_tag="VQ664_000910"
     CDS             13225..13533
                     /locus_tag="VQ664_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET2789092.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQSSGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            13550..14848
                     /locus_tag="VQ664_000911"
     CDS             13550..14848
                     /locus_tag="VQ664_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET2789093.1"
                     /translation="MSKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLSSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASANLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQTLGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVITQLVILAMSTLVYFPFFKVQDRLAYQNEIKQS"
     gene            14999..17437
                     /locus_tag="VQ664_000912"
     CDS             14999..17437
                     /locus_tag="VQ664_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HET2789094.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMTIYIEEESMIAGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKVALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPATTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            17456..18124
                     /locus_tag="VQ664_000913"
     CDS             17456..18124
                     /locus_tag="VQ664_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HET2789095.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHEIRRQAGDDIFIKVPVTPAGLRAIKVLK
                     KEGYHITATAIYTVIQGLLAIEVGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVTQN
                     SRSI"
     gene            18142..19230
                     /locus_tag="VQ664_000914"
     CDS             18142..19230
                     /locus_tag="VQ664_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HET2789096.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNYPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
     gene            19685..22186
                     /locus_tag="VQ664_000915"
     CDS             19685..22186
                     /locus_tag="VQ664_000915"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HET2789097.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSTEQ
                     AEAVADYKHQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEIPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDA
                     IAKIVAWLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGGLVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLIRSKEIVAENNGALD
                     KVYNETVKAVTEQIDSLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFIQLIAPFAPHL
                     AEELWQTVAATGESISYVTWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDLSREEL
                     QEIALADEKVKAEIDGKEIVKVISVPNKLVNIVVK"
     gene            22380..23075
                     /locus_tag="VQ664_000916"
     CDS             22380..23075
                     /locus_tag="VQ664_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2789098.1"
                     /translation="MPVNEYGQMIGESMEGYTPGELPSIDFLEGRYARIEALSVEKHA
                     EDLLAVYGPDTPQEMWTYLFQEPVADMGELVSLLHQMLARKDRFYYAIIDKATGKALG
                     SFSLMRIDQNNRVIEVGAVTFSPELRGTRIGTEAQYLLARYVFEELNYRRYEWKCDAL
                     NLPSRRAAERLSFIYEGTFRQAVVYKGRTRDTDWLSMIDKDWPQVKDRLETWLRPENF
                     DKNGQQYKSLREL"
     gene            23087..23503
                     /locus_tag="VQ664_000917"
     CDS             23087..23503
                     /locus_tag="VQ664_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2789099.1"
                     /translation="MITIKKQEIVKLEDVLHLYQAVGWTNYTHQPEMLEQALSHSLVI
                     YLALDGDAVVGLIRLVGDGFSSVLVQDLIVLPIYQRQGIGSALMKEALEDYKDAYQVQ
                     LVTEETERTLGFYRSMGFEILSTYNCIGMTWMNRKK"
     gene            complement(24130..24222)
                     /locus_tag="VQ664_000918"
     CDS             complement(24130..24222)
                     /locus_tag="VQ664_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HET2789100.1"
                     /translation="MMELVLKTIIGPIVVGVVLRIVDKWLNKDK"
     gene            24383..25354
                     /gene="ruvB"
                     /locus_tag="VQ664_000919"
     CDS             24383..25354
                     /gene="ruvB"
                     /locus_tag="VQ664_000919"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HET2789101.1"
                     /translation="MGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEAAKMRDEALD
                     HVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELEPGDVLFIDE
                     IHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTRAGMLSNPLR
                     ARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPRIANRLLKRV
                     RDFAQIMGNGVIDDIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGGPVGLGTLSV
                     NIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            25335..25907
                     /locus_tag="VQ664_000920"
     CDS             25335..25907
                     /locus_tag="VQ664_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HET2789102.1"
                     /translation="MNTVKNKQEILEAFRENPDMMAILTIIRDLGLKDSWLAAGSVRN
                     FIWNLLSDKSPFDHETDIDVIFFDPDFSYEETLLLEKKLREDFPQYQWELKNQVYMHQ
                     HSPHTASYTSSRDAMSKYPERCTAVGLRLNEESDFELYAPYGLEDILNFQVRPTPHFL
                     ENEDRMELYQTRLSKKNWQEKWKNLIFKNT"
     gene            26138..26896
                     /locus_tag="VQ664_000921"
     CDS             26138..26896
                     /locus_tag="VQ664_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HET2789103.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            26905..27708
                     /locus_tag="VQ664_000922"
     CDS             26905..27708
                     /locus_tag="VQ664_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HET2789104.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKMRGLETMTMEGLLTLFATFALTIPLENYLIFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            27730..28989
                     /gene="rseP"
                     /locus_tag="VQ664_000923"
     CDS             27730..28989
                     /gene="rseP"
                     /locus_tag="VQ664_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HET2789105.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPEDSQG
                     RYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            29002..30855
                     /locus_tag="VQ664_000924"
     CDS             29002..30855
                     /locus_tag="VQ664_000924"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HET2789106.1"
                     /translation="MKQSKMPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPALLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTAEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            30955..32334
                     /gene="bglA"
                     /locus_tag="VQ664_000925"
     CDS             30955..32334
                     /gene="bglA"
                     /locus_tag="VQ664_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HET2789107.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTVFRTSIQWSRIFPQGCGKVNPQGVDFYRK
                     VFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIHDNTVDFLGVNYYQPLRVMAPRFAKHPESPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KKLSDNNGF"
     gene            32526..34334
                     /gene="glmS"
                     /locus_tag="VQ664_000926"
     CDS             32526..34334
                     /gene="glmS"
                     /locus_tag="VQ664_000926"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HET2789108.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYLEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEDGLSVLEAFKKALHIIRGSYAFAL
                     IDSENPDVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNRRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDEAGQ
                     VVVDPDIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLVHELSIVAQSIESTLSEKET
                     IEAKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLALLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
BASE COUNT        10494 a         5879 c         7580 g        10513 t
ORIGIN      
        1 aaaaagtatt gacaaatttg aaataaagcg tttttcgcac ttgcaaaaat ccgctacaaa
       61 tgttatactg agatagtctg acttataatt gttgtctctg tgtctagagg catcgaatcg
      121 aaatttatgg aggtgctttt gcgtggcaaa agacgatgtg attgaagttg aaggcaaagt
      181 agttgataca atgccgaatg caatgtttac ggttgaactt gaaaatggac atcagatttt
      241 agcaacagtt tctggtaaaa ttcgtaaaaa ctatattcgt attttagcgg gagatcgtgt
      301 tactgtcgaa atgagtccat atgacttgac acgtggacgt atcacttacc gctttaaata
      361 atcgaaaaac ttggagggat aagaaatgaa agtaagacca tcggtcaaac caatttgcga
      421 atactgtaaa gttattcgtc gtaatggtcg tgttatggta atttgcccag caaatccaaa
      481 acacaaacaa cgtcaaggat aagatagaaa ggagaaaaca tggctcgtat tgctggagtt
      541 gatattccaa atgacaaacg cgtagtaatc tcattgactt atgtttatgg tatcggactt
      601 gcaacatcta agaaaatttt ggctgctgct ggaatctcag aagatgttcg tgtacgtgat
      661 cttacatcag atcaagaaga tgctatccgt cgtgaagtgg atgcaatcaa agttgaaggt
      721 gaccttcgtc gtgaagtaaa cttgaacatc aaacgtttga tggaaatcgg ttcataccgt
      781 ggtatccgtc accgtcgtgg acttcctgtc cgtggacaaa atactaaaaa caacgctcgc
      841 actcgtaaag gtaaagctgt tgcgattgct ggtaagaaaa aataatatag gaggtaaaag
      901 tcttggctaa accaacacgt aaacgtcgtg tgaaaaagaa tatcgaatct ggtattgctc
      961 atattcacgc tacatttaat aacactattg ttatgattac tgatgtgcat ggtaatgcaa
     1021 ttgcttggtc atcagctggt gctcttggtt tcaaaggttc tcgtaaatct acaccattcg
     1081 ctgctcaaat ggcttctgaa gctgctgcta aatctgcaca agaacacggt cttaaatcag
     1141 ttgaagttac tgtaaaaggt ccaggttctg gtcgtgagtc agctattcgt gcgcttgctg
     1201 ccgctggtct tgaagtaaca gcaattcgtg atgtgactcc agtgccacac aatggtgctc
     1261 gtcctccaaa acgtcgccgt gtataatcat cgcattacac tgcttttcgt ttaagaggga
     1321 gtaactaaat gatcgagttt gaaaaaccaa atataacaaa aattgatgaa aataaagatt
     1381 atggcaagtt tgtaatcgaa ccacttgaac gtggctacgg tacaactctt ggtaactctc
     1441 ttcgtcgtgt acttctagct tctctaccag gagcagctgt gacatctatc aacattgatg
     1501 gtgtgttaca tgagtttgac acagttccag gtgttcgtga agacgtgatg caaatcattc
     1561 tgaacattaa aggaattgca gtgaaatcgt acgttgaaga cgaaaaaatc atcgaactgg
     1621 atgttgaagg tcctgctgaa gtaacagctg gtgacatttt gacagatagc gatattgaaa
     1681 ttgtaaatcc agatcattat ctctttacaa ttggtgaagg ttcttctcta aaagcgacta
     1741 tgactgttaa cagtggtcgt ggatatgtac ctgctgatga aaataaaaag gataatgcac
     1801 cagttggaac acttgctgta gattctattt atacaccagt tacaaaagtc aactatcaag
     1861 tggaacctgc tcgtgtaggt agcaatgatg gtttcgacaa attaaccctt gaaatcttga
     1921 caaatggaac aattattcca gaagatgctt tagggctttc agcacgtatt ttgacagaac
     1981 atcttgattt gtttacaaat cttactgaga ttgctaagtc aactgaagtg atgaaagaag
     2041 ctgatactga atctgacgac cgtattttag atcgtacgat tgaggaactg gacttgtctg
     2101 tgcgttcata caactgttta aaacgtgccg gtatcaatac tgtgcatgat ttgacagaaa
     2161 aatctgaagc agagatgatg aaagtacgaa atcttggacg caagagtttg gaagaagtga
     2221 aactcaaact cattgatttg ggtcttggat taaaagataa ataaaggagg aatacatggc
     2281 ttaccgtaaa ctaggacgca ctagctcaca acgtaaagca atgcttcgcg atttgacaac
     2341 tgaccttttg atcaacgaat caatcgtgac aactgaagct cgtgctaaag aaatccgtaa
     2401 aactgttgaa aaaatgatta ctctaggtaa acgtggtgat ttgcatgcac gtcgtcaagc
     2461 agctgctttc gtacgtaatg aaatcgcatc tgaaaactat gatgaagcaa ctgataagta
     2521 cacttctact acagcacttc aaaaattgtt ctcagaaatc gcacctcgtt atgctgaacg
     2581 taacggtgga tacactcgta tccttaaaac tgaaccacgt cgtggtgatg cagcgccaat
     2641 ggcgatcatc gaattagtat aaaatcatca attttgttga gtgttatgat gatggagtct
     2701 tgtgctctta gtctagctct ggtctaccgc taggatttcg gtcctagcgg gaacactcat
     2761 cataagttgg gatagtagac gcttgtttac gaaattgttt ttttcttaag aacaacttcg
     2821 taagcaggcg tttttgagta ttttcgttag aattatgcta tactatttga aaagaatcct
     2881 gtttaatgtt aaggtttctt attttaagaa gaattggagt ttacttatga aagccattat
     2941 aactgttgtt ggtaaagata aatctggaat tgttgcaggt gtttctggta aaattgcaga
     3001 attaggattg aatattgacg atatctctca aactgtcttg gatgaatatt ttacgatgat
     3061 ggctgttgta tctagtgatg aaaagcaaga ttttacctat cttcgtaatg aatttgaagc
     3121 ttttgggcaa actttgaatg taaaaatcaa tattcagagt gcagcgattt tcgaagctat
     3181 gtataatatc taggaggtca tcatggatat tagacaagtt actgaaacca tcgccatgat
     3241 tgaggagcaa aacttcgata ttagaaccat taccatgggg atttctcttt tggactgtat
     3301 cgatccagat atcaatcgtg ctgcggagaa aatctatcaa aaaattacga caaaggcggc
     3361 taatttagta gctgttggtg atgaaattgc ggctgagttg ggaattccta tcgttaataa
     3421 gcgtgtatcg gtgacaccta tttctctgat tggggcagcg acagatgcga cggactacgt
     3481 ggttctggca aaagcgcttg ataaggctgc gaaagagatt ggtgtggact ttattggtgg
     3541 tttttctgcc ttagtacaaa aaggttatca aaagggagat gagattctca tcaattccat
     3601 tcctcgcgct ttgactgaga cggataaggt ctgctcgtca gtcaatatcg gctcaaccaa
     3661 gtctggtatt aatatgacgg ctgtggcaga tatgggacga attatcaagg aaacggcaaa
     3721 tctttcagat atgggagcgg ctaagttggt tgtattcgct aatgctgttg aggacaatcc
     3781 atttatggcg ggtgcctttc atggtgttgg ggaagcagat gttatcatca atgtcggagt
     3841 ttctggtcct ggtgtggtga aacgtgcttt ggaaaaagtt cgtggacaga gctttgatgt
     3901 agtagccgaa acagttaaga aaactgcctt taaaatcact cgtatcggtc aattggttgg
     3961 tcaaatggcc agtgagagac tgggtgtgga gtttggtatt gtggacttga gtttggcacc
     4021 aacccctgcg attggagact ctgtggcacg tgtccttgag gaaatggggc tagaaacagt
     4081 tggcacgcat ggaacgacgg ttgccttggc cctcttgaac gaccaagtta aaaagggtgg
     4141 agtgatggcc tgcaaccaag tcggtggttt atctggcgcc tttatccctg tttctgagga
     4201 tgaaggaatg attgctgcag tgcaaaatgg ctctcttaat ttagaaaaac tagaagctat
     4261 gacggctatc tgttctgttg gattggatat gattgccatc ccagaagata cgcctgctga
     4321 aaccattgcg gctatgattg cggatgaagc agcaatcggt gttatcaaca tgaaaacaac
     4381 agctgttcgt atcattccca aaggaagaga aggcgatatg attgagtttg gtggtctatt
     4441 aggaactgca cctgttatga aggttaatgg ggcttcgtct gtcgacttca tctctcgcgg
     4501 tggacaaatc ccagcaccaa ttcatagttt taaaaattaa gaaaatagga gaaattttaa
     4561 gttctattta agattagatg tgtatactat aatcattaaa taaagacctc ctaatattat
     4621 ttgaaacaga taacactgaa ttagtttgaa tttgattttc atctaatatc tttatttaat
     4681 gaactcctaa actttttcat aataatctcc ttcaaaagtc gcctgtatgg gtggctttta
     4741 ttttatcatt catgatataa tagaagcaaa cggaggacgg aaaatggtaa aagtacgatt
     4801 gtatttggta cgtcatggca agaccatgtt taacacgatt ggtcgcgcgc aaggttggag
     4861 cgatactccc ttaactgctg aaggtgaacg agggattcaa gagttaggaa tcggtttgcg
     4921 agaatctgat ctacagtttg agcgcgctta ttcgagtgat tctggtcgta ccattcagac
     4981 catgggaatt atccttgaag aacttggctt gcaggggaaa atcccttatc gcatggacaa
     5041 gcgtatcaga gaatggtgtt tcggtagttt tgatggagcc tatgatggcg atcttttcat
     5101 gggcattatt cctcgtatct ttaatgtgga ccacgttcac caattgtctt atgctgaact
     5161 ggctgagggc ttggtagagg tcgatacagc tggttgggct gaaggctggg aaaaactcag
     5221 tggccgaatc aaggaaggct ttgaaatgat tgcaaaagaa atggaagatc aaggtggagg
     5281 taacgccctt gttgtcagcc atggaatgac tattggaacc attgtttatc tgattaatgg
     5341 catgcatccg catggtctag ataatggtag cgtgacgatt cttgaatatg aggacggtca
     5401 gtttagggtt gaagttgtcg gtgaccgtag ttaccgagag ctaggatgtg agaagatgga
     5461 agaaggctct atttaatcag tctagacttg cttgccatga gctagggatt tgataagaat
     5521 atcaagataa gaaaaaacag ccgagggcac tcctttcggc tgtttttgat gtggaaaact
     5581 aaagtgtaat gctattgctt ttagagattt tcataaacaa gagcaaggaa cctactgtta
     5641 gaacagtcag gatagttgac aaggctgcgg ctacaccgta atttcctctg agaacctctg
     5701 tataaatagc tacagtcatt gttcttgttt tgacattgta gaggaggata gaagtagaga
     5761 gttttgaaat cattgtgacc caagataaga tggctccaga aatgatacca gatagcatca
     5821 ttggagttgt aatcttagca aaggtattga gacgactact tcctaagctt tcagcagctt
     5881 cttcaatact tggtgctatt tgttgtaagc tagcaacaga tgagcgaata gtataaggta
     5941 atcttctgac agatagagac ataatcaaga tgaaagcagt ccctgtaatc ataagaaatc
     6001 cacttccaaa tagaccagta ttgaaggaag aaatgaaggc aatccctaga acggttcctg
     6061 gtacaatata aggtaccata ctgaggctgt caattaagtt tgtaaacaaa ttccgttttc
     6121 taacggctag gtaggagata aatgtcgcaa atagaacaac tagaactaag gcaatcaaag
     6181 ggatacgaat ggtattgaaa atagcagatc ccatacgatt gaaagctacc ttgtaactgt
     6241 ttggagaata acctttaaca gataccatac ctgatgtttt taggaaagag gtataaatta
     6301 agtagatttg aggtaaaaca gagataaaga taattccgta gactgttgca taaatggcag
     6361 ctatttttcc ttttgtagtt tttttaggct caattggatg gagcagattc atgctgaaac
     6421 tgtagcggtt tgcaatgtgt ttttggataa ggaaaattgc caaggcaatg ataatcgcca
     6481 taattgcaaa agcagaattt cctccaacct cgctaataaa ttgggtataa atcaggacag
     6541 ggaaagtccg atatccttcg tcaatcaaca taggcgttcc aaagtctgag aatgctctca
     6601 taaatacaag caaggagctg ctagtaaggt tggaactagg agaggtaaaa caaccgttac
     6661 gatacgctta aatccgaagg accccatgct ttcagctgct tcaagtagag aattgtcaat
     6721 actgttcatt gttccagcaa catatagaaa taccagtggg aatagttgca gtgtaaagac
     6781 aagtacaatt cctttgaatc cataaatatc gatagctgga agatgaaggg catttgtcaa
     6841 aaatttagtg atgacctcat ttcgtcccag caagagaatt caggagtagg ctcctacgaa
     6901 aggagctgac atggaagcaa tgataatcaa tatttgtaga aatttcttcc ccttgaagtc
     6961 atacatagag aagagataag ctaatagggt tcctacaact aaggaagtga tagtagcggt
     7021 aatggaaacc ttgaaactgt tgactagtgt ctcagagtag taggctttac taaagaaagt
     7081 gacaaaatta gctagtgaga attgtccttc atgtataagt gcttgcttga gcacggtaac
     7141 gataggataa acgagaaaga caagataggt aagaaagatg aagaaagagg aagctgtcca
     7201 aatatttagt tttttacatt ccatggttga ctccttttat caggttttgg gaaccatctg
     7261 cagaaaagat gtttaatttt tgcgtattga ttcgtagacg aatacgattg cctttttgta
     7321 gttcttcttc aaaagttgat tcttcactaa cttaaatttt tgaggcaaaa cctgtctcaa
     7381 tgaaatactc cgtatttagt ccaagataga cgctatcgct aatagttcct tcgatatctc
     7441 cagattcatc tttgataaac tcttcgggac gaatgcttac atgaatagct tgctcctcaa
     7501 cctgatcaag agctggcatt cgaagggcat agccatctga aaagacgata taagcgccgt
     7561 cgctccgttt ttcaagattg gcagggataa tatttgtgcg tccgataaag gttgccacaa
     7621 actcattagc tggtttatga tagagttatt ttggtcggcc gatttgttgg atcaccccat
     7681 ctttcataac agcaatttgg tctgaaatag ccatggcttc ttcttggtcg tgggttacat
     7741 aaacagttgt aattcccact tcgtgttgga tttctcggat ggcttgacgc atatccaagc
     7801 gaagtttggc ctccagatta ctaagtggct cgtccatgag gagaacactt ggattaaccg
     7861 ctaaggcgca tgccaaggtg acacgttgtt gttgtccacc actgagttta tcgggctttc
     7921 gatccgcata ttgagcaatt tgcatgagtt caagatactt gttggtctgt tgaatcaatt
     7981 cttcttttgg aaccttcttt tgcataagac caaaagcaac gttgtctcgg acagtcaaat
     8041 gtgggaaaat agcgtagttt tggaaaacca tcccgatatt gcgtttgctg ggttccatat
     8101 tattgatttt tgtatcatcg aagtaaaatt ctccaccttc gatactgttg aaacctgcaa
     8161 tcatacgaag aagggtcgtt ttcccacatc ctgaagctcc aagaagggta aagagacttc
     8221 cttttggaat tgtaatgttc aaattctcaa taacagggac atcgtggtag atttttttgg
     8281 cgttaataat ttcgatctca ctcatagtga acctctttta ctgtttagat tggatatctg
     8341 taaagacttc gttgtatttc ttaacgatat ctgatttatt cttgatgaca taatcataat
     8401 cttcagtgag tgttttgatt ttgtcaattg gtttcatgtt ttcgcttgtt ttagcatttt
     8461 tacgaacagg acggttagta gtggttgtac caagtgtatc ttgtacttct tgagagataa
     8521 taaaatcgat aaatttcttg gcattttcca tatttttaga ttttttaacg atagcagcac
     8581 tagcaggtag gaagacggtt ccttcttttg gatagactac cttaatgtta gctccgtcat
     8641 ttaagagttt aactgctgga tcttcataag agagactaac agtcatttct ccatcagcga
     8701 ctgctttata gacaccagat gaacttaaac cgattttata gtatattgaa actagaatag
     8761 tacacatcta cttctaaaac attgttagaa atcgatttga ctgtcctgat taatttgtcc
     8821 tgttcttatt tcattttact ataccatcaa taagtgtgaa aagatctttt acataagacc
     8881 aagccttatc atctttgtaa ccaccttgag cttgtagcat atttgttaat tgagcaaagg
     8941 cgctagaaga gtttgctggg tcagcagttg cgatttttcc ttttagttca ggtttgagaa
     9001 ggtcgctata tccttcgatg ttcatgcctt tagttaaatc agggtggacg attaaaacac
     9061 taccatctag tgtataagga gtagagaagc cagttgtgtt ttgatattct ttgataacat
     9121 tatcattttc ttttgaaata tagttttcaa agagttctcc gtgggtagca tattgtgtat
     9181 aagaaccacc aaagataata tcagctacag gaacttcttt ttctgactct agttttttga
     9241 aaagttctcc agtaccagct tgaatcagtt ctattttgat accatatttt tcttcaaagg
     9301 caggaatagt tgctccaatt aagccttctg agtttggtga ataaacgact agcgaaccac
     9361 cgtctccttt atcagatgaa ctgtcatcgg cagattcatt agaagaacaa gcagcataat
     9421 acatccattt ctttttcatg atggatacct ccgttgtgtt atttaagttt attttaaaac
     9481 aatgtaagcg tttttaaaac ctacaattct attctatagt gtattgaatc tataacagta
     9541 cacattgact gctaaaatat ttctataaat taatttgact ttcctgatag agatgttcac
     9601 atcttatttc aattcactat attagagtaa aattctctac aaaaaaaaag aatagcctat
     9661 tttactattt ttccgagtga tttcaattcc tttggggaaa tatggagata ctttttaaat
     9721 cctgacaaat ggttgtttct ttttctaaat cggtgatact gtatcggaga atgcgcgtga
     9781 ggtcacaaag gctgcgatag agcttctatg gagaatttct ttttggagag attttttaaa
     9841 ggaatgagac atccgctacc tccttggaag gtttttttgt gataagtata gcagtttaaa
     9901 aattctagag caaggtaaaa tagaaaaggt ttggctaaaa ttttttagct aaaccttttg
     9961 aaaagttaag tatgtattat agatgcttgt tatctgcaaa tagctagagc atttcaagga
    10021 aataaactag aaataacaat taatatggtg gttcagaaat accttttgat aatcaataag
    10081 atcttcagga tgaagtgcgt tgattccatc catttcatat ttccgattta ataaacgata
    10141 tttgttttca ccaaattgat gaaaagggag tagttgaact tggtcgatat ttaatgagtt
    10201 aaatagagta gcgaattttt ctgcatcctc taaactattg ttaaaattag gaataactgg
    10261 gattcttaaa acgatagttt tattttgtga aaaagcataa tgaatgtttt taataatcat
    10321 ttgattaaaa accccagtca cttttttatg ttttatagaa ttataatgtt ttaggtctgt
    10381 gtagataaaa tccacatatt gaattaaatc aataaatttt tcatgatcaa caaaggcagt
    10441 agtttcaatg gcagtgtgta tgtgatgttc tttagctgat tttaagatag ctttagcaaa
    10501 ttcaaactga gcaaatattt cacctcctga taaagttaaa cctccaccgg attcttcgta
    10561 aaattctttg tcttttaata cctctgtaat aatttcttct acagtctttt cttcaccgac
    10621 taaggtgaat ttctctcgtt gagcatcttt cattttttca ggtttcattc tttgagattc
    10681 aggattagaa caccatggac agcgcagagg acatcctttt aaaaaaacag ttgtacgaat
    10741 acccgggccg tcatgaattg aaaagtgttg aatattaaaa ataattcctt tagatatttc
    10801 cataagagtt cctcctcttc ataagtctat cctatcacaa aaacgaaaga aaaacaatta
    10861 cgaacgaaag gttaatttgt tgttttttgc tttttatttt ggtagaataa aacggaggtg
    10921 taaaatgaaa agattggaac aaattattaa attagtatca gaatatgaaa agatcgacgt
    10981 taatacatta tcggaaaaat taaatgtatc gaaagtaacg attagaaaag atttagataa
    11041 attagagtca aaaggtttat tacacagaga gcatggatat gctgtattaa atagtggaga
    11101 tgacttaaat gtacgtttgt caattaatta tgaaattaag agaaaaattg ttcaggaagc
    11161 agtaaaattg gtgtcagata atgaaacgat aatgatagaa tctggatcga cctgtgcttt
    11221 acttgctgag gaaatttgca agcaaaaaag aaatgttacg attgtaacaa attcattttt
    11281 tatagcaaat tttgtgagag cttatgattc atgtcgtatt attgttcttg gtggagagtt
    11341 tcagaaggat tcacaggtta ctgtgggacc tttattaaaa gaaatgatac agacttttca
    11401 tgtgcatcaa gcttttgttg ggacagatgg atacgataaa gagatgggct ttacaggaaa
    11461 agatttaatg cgcagtgagg tagttcaata tatttcagca gcgtcggata aagtcattgt
    11521 cctaactgac tcaagtaaat ttgataaaag gggtacagta agaagatttg ctttaagtca
    11581 agtctatgaa gtaataacag acgaaaaact ttctaaacaa aatatagcta cattagaaaa
    11641 tgctgggata atggttaagg tagtttcgta agaggttaag tgtatgaatc aagataggaa
    11701 taaactgctc tctaaaattg cttatctgta ttatattgaa aacttaaatc agtcacaaat
    11761 agcagcaaaa ttaggaattt atagaacctc tattagtaga atgttaacag aagcaaggaa
    11821 tgcaggaatt gttaaaattg aaatagagaa ttttgatacc aatatgttta agttggaaaa
    11881 ttatgtaaaa gaaaaatatg gtctggaaag tttagaaatt attccaaatg aatttgatga
    11941 taatccaaca attttatctg aaagaatttc tcaagttgca gcaggtgtcc ttaggaatct
    12001 aattgatgat aatatgaaaa ttggcttttc ttgggggaaa agtttaagta atttagtaga
    12061 tttaattcac agtaaaagtg tccgaaatgt tcacttctat cctctagcag gtggtcctag
    12121 tcacatacac gctaaatacc atgtgaatac actgatttat gaaatgtcta gaaaatttca
    12181 tggagagtgt acatttatga atgcaacgat tgtgcaagaa aataaattgt tagcagatgg
    12241 tattttgcaa tcaagatatt ttgaaaattt gaaaaatagt tggaaagatt tagatatagc
    12301 tgtagtcgga attggtgatt ttagcaataa aggaaagcat caatggttag acatgcttac
    12361 agaggatgac tttaaagaat tgaccaaagt taaaactgta ggagaaattt gttgtcgatt
    12421 ttttgattca aaaggtaaag aagtctatga aaacttacag gaaagaacga tagcaatctc
    12481 tttggaagat ttaaaaaata ttcctcaaag tttagctgtt gcttacggtg atacgaaagt
    12541 atcttcgatt ctttctgtct tgcgtgctaa tttagtaaat catttgatta cagacaaaaa
    12601 tacaatttta aaagttttgg aagaagatgg ggatttgact tttagagaga ttctaggtga
    12661 gtgaaaatga tagactgatt cagtttatcg tttttctttt tagttgattg cacatttgtg
    12721 cttatataaa caaaaatagt ttatctgttg tttttggatt gacaacttta ttatgtagtt
    12781 gtattctata gttacaaaag aaaattttaa aatttcaaat gaaaaaagct ttttacatag
    12841 tgaaatgagg aggaatttat ggaaattatt gttccagatc aaattatcat gggtttaatt
    12901 ttatatgctg gtgatgcgaa acaacatatt tataaagcgt tagattacat aaaaaatggt
    12961 acatgtgaac ggtgtgaaga agaaatccag ttagctgatg ccgccttatt agaagcccat
    13021 aatctacaaa caaaattctt ggcacaagaa gcgtctggta caaagacaga aattacagct
    13081 ctctttgttc attcacaaga tcatctcatg actagtatga cggagattaa tttaatcaaa
    13141 gaaattatta gtttgagaaa agaacttcat aaaaaataat actagagtat tatcattgtt
    13201 attaacatag aggaggaaaa cataatggtg aagattggtt tgttttgtgc agcaggtttt
    13261 tctactggta tgcttgtaaa taatatgaaa attgcagcgc aatctagtgg agttgaggca
    13321 gaaatagagg cgttttctca gtctaaatta gcggattatg cgccaaatat agatgttgca
    13381 ctattgggtc cacaagttgc ttatacatta gataaatcaa aagaaatttg tgataagtgt
    13441 gatgttccga tagctgttat tccgatgatg gactatggta tgttagatgg gaaaaaagta
    13501 ttagatttgg ccctatcttt gattagtggg taagaaaagg agatttatta tgtcaaagat
    13561 ggatgttcag aaaatcattg caccgatgat gaagtttgtg aatatgcgtg gcattatagc
    13621 tctaaaagat gggatgttag caattttgcc attgacagta gttggtagtt tgttcttgat
    13681 tatgggacaa ttgccgttcg aaggattaaa taagagcatt gctagtgttt ttggagctaa
    13741 ttggacagag ccgtttatgc aagtatattc aggaactttt gctattatgg gtctaatttc
    13801 ttgtttttca attgcctatt cttatgctaa gaatagcgga gtagaggctt taccagctgg
    13861 agttctatct gtatctgcat tctttatttt gctaagatca tcttatatcc ctaaacaagg
    13921 tgaggcgatt ggggacgcta ttagtaaagt ttggtttgga ggccaaggaa ttatcggtgc
    13981 tatcattata ggtttggtag taggaagtat ttataccttc tttataaaga gaaaaattgt
    14041 tattaagatg ccagaacaag ttccacaagc tattgccaaa cagtttgaag caatgattcc
    14101 agcatttgta attttcttat cttctatgat tgtatatatt ttagcgaagt cattgactaa
    14161 tggcggaaca ttcatagaaa tgatttattc tgctattcaa gttccgttgc aaggtttaac
    14221 tggatctttg tatggtgcta ttggaattgc attctttata tcatttttgt ggtggtttgg
    14281 tgttcatggg caatcggtag taaatggagt agtgacagct ctgcttttat ctaatcttga
    14341 cgctaataaa gctatgttag cctctgctaa tctatcatta gaaaatggtg cacatattgt
    14401 tactcaacaa tttttagatt catttttaat tctatcaggt tcagggatta cgtttggtct
    14461 tgtagttgcc atgctttttg cagcaaaatc aaaacaatac caaaccttag gaaaagttgc
    14521 agcttttcca gcaatattta acgtaaatga gccagttgta tttggatttc cgattgtcat
    14581 gaatccagtt atgtttgtac ctttcattct tgttcctgta cttgcagctg tgatagtata
    14641 tggagctatt gcaacaggtt tcatgcagcc attctcaggg gtaacattgc cttggagtac
    14701 accagctatt ttatcaggat ttttggtggg tggatggcaa ggagttatta ctcagctggt
    14761 gatattagcg atgtctacat tggtttattt tccattcttt aaagtacagg atcgtttagc
    14821 ttaccaaaat gaaatcaaac aatcttagag gtatttgtgt gttactgtta aactcacaca
    14881 tttgtgctaa aaattagaga gttaaaattt ttctagttaa aagcttgaaa atttctataa
    14941 aaatcggtat tatattttcg aaagaaataa aaatattttc gaaagaaagg tggttacgat
    15001 ggtaaataca gaagtagcaa gaacaacaat caagacagaa tattttggca gccttactga
    15061 aaggatgaac aaatatcgag aagatgtttt aaataaaaaa ccttatattg atgctgagag
    15121 agcagttcta gcaacacgcg cctatgaacg atacaaggaa caacctaatg tcctaaaacg
    15181 tgcatatatg ctgaaagaaa ttttggaaaa tatgactatc tatattgaag aagaatctat
    15241 gattgcggga aatcaagctt cttccaataa agatgctcct atttttccgg aatatacgct
    15301 agaatttgtt ctcaatgagt tggatctttt tgaaaagcgt gatggagatg ttttctatat
    15361 tacagaagaa acaaaagaac aacttagaag tattgctccg ttttgggaaa ataataattt
    15421 acgtgctaga gctggtgcct tattacctga agaagtgtct gtttatatgg aaacaggatt
    15481 cttcggtatg gaaggtaaga tgaattctgg agatgctcac ctagcagtta actatcagaa
    15541 acttttgcaa tttggtttaa gaggttttga agagcgggct cgtaaagcaa aagtagctct
    15601 agatttaaca gatccagcaa gtattgataa atatcatttt tacgactcta tatttatcgt
    15661 aatcgatgct attaaagtat atgcaaagcg ctttgttgct cttgctaaaa gtttagccga
    15721 aaatgcaaat cctaaacgta agaaagaatt acttgagatt gcagatattt gctctagagt
    15781 cccatatgaa ccggcaacta cttttgcaga agctattcaa tcagtttggt ttattcaatg
    15841 tattttacaa attgaatcta atggccactc tctttcatat ggccgttttg atcaatatat
    15901 gtatccatat atgaaggctg atttagaaag tggtaaagaa acagaagata gcattgttga
    15961 acgtctgaca aatctttgga ttaagacaat tacaatcaat aaggttcgca gtcaatcaca
    16021 tacattttct tcagcaggaa gtcctttata tcaaaatgtt acaattggtg gacagactcg
    16081 agataagaag gatgctgtta acccattatc ttatttggta ttaaaatcag ttgcacaaac
    16141 ccatctaccg caacctaatc taactgtacg ttaccatgca ggtttagatg ctcgtttcat
    16201 gaatgagtgt attgaagtga tgaaacttgg ttttggtatg cctgcattta ataatgatga
    16261 gattattatt ccttctttta ttgcaaaagg agtattggaa gatgatgctt atgattacag
    16321 tgccattgga tgtgttgaaa cggcagttcc agggaaatgg ggctatcgtt gcacaggtat
    16381 gagttatatg aacttcccta aggttctact tatcacgatg aatgatggaa ttgatccggc
    16441 ttcgggtaaa cggtttgcac caagctttgg tcattttaag gatatgaaga acttttctga
    16501 attagaaaat gcttgggata aaacactaag atatttgaca cgaatgagtg ttattgttga
    16561 aaattctatt gatttatcat tggaacgaga agttcctgat attctatgtt cagcattgac
    16621 tgatgattgt attggtcgtg gaaaacacct taaagaaggt ggagcagtat atgattatat
    16681 atcaggattg caagttggaa ttgcaaattt gtcggattca ttagctgcaa ttaaaaaatt
    16741 ggtgtttgag gaagaacgta taagcccaag tcagctttgg catgcactgg aaacagatta
    16801 tgccggagaa gaaggtaagg tcattcaaga aatgttgatt catgatgcac ctaagtatgg
    16861 taatgatgat gattatgctg acaaattggt tactgctgct tatgacattt atgttgatga
    16921 aattgctaaa tatcctaata cacgttatgg aagagggcct attggaggaa ttcgttattc
    16981 aggaacatct tctatctcag ccaacgtagg gcagggacgt ggaacattag caactccaga
    17041 tggacgcaac gcgggtacac cgttagcaga gggttgttca ccatcacata atatggatca
    17101 acacggccct acatctgttt taaaatctgt ttcaaaatta ccaacagatg aaatcgtagg
    17161 tggggttctc ttaaatcaga aagtaaatcc tcaaacgtta gccaaagaag aagataaatt
    17221 aaaactaatt gctttgttac gaacattctt taatcgttta catgggtacc atattcaata
    17281 caatgttgtt tccagagaga cgttgattga cgctcagaaa catcctgaaa aacacagaga
    17341 cttaattgtt cgtgttgcag gatactctgc attcttcaat gttctttcta aggcaaccca
    17401 agatgacatt ataggacgta ctgagcatac tttgtaaaat aaagaggttc tttttatgga
    17461 atttatgctt gacacattaa atttagatga gattaaaaag tggtctgaaa ttttgccgct
    17521 agctggggta acttcaaatc ccactattgc aaaaagagag ggttctatta atttttttga
    17581 acgaatcaaa gatgtaagag aattgattgg ctctacaccc tctattcatg ttcaggtgat
    17641 ttctcaagat tttgaaggca tcttaaagga tgctcatgaa attcgaagac aagcaggaga
    17701 tgatatattt atcaaagtac ctgttactcc agctggatta cgtgcaataa aggtgctaaa
    17761 aaaagagggc taccatatca ctgcaacagc tatttataca gttattcagg gattattagc
    17821 tatcgaagta ggagcggatt acctagctcc atattataat agaatggaaa atctgaacat
    17881 tgattcaaat tctgtcattc gtcaattagc tcttgctatt gatagacaga actctcctag
    17941 taagatttta gctgcatcct ttaaaaatgt agcacaagta aataatgctt tagctgcagg
    18001 tgcgcatgct gttacagcag gagcagatgt ttttgaatca gctttcgcca tgccatctat
    18061 ccaaaaggcg gttgatgatt tttctgacga ttggtttgtt actcaaaata gtcgttccat
    18121 ttagatagag aggaaataca tatgagaatt tttgctagtc cttctagata tattcagggg
    18181 gaaaatgcct tgtttgaaaa tgccaaatca attttggatt tgggaaatta ccctattcta
    18241 ttatgcgatc agttggttta tgatattgtt ggaaaacgat ttgaagatta tctacatagg
    18301 tatggtttcc atattgttct ggcgctattt aatggtgaag cttctgacaa tgaaatcaat
    18361 cgagttgttg ccttggctga gaaagaaaat tgtgatagta ttatcggtct tggtggggga
    18421 aagacgattg atagcgcaaa agctattgca gatttgattg aaaagcctgt tattattgct
    18481 ccaacaattg catcgaccga cgcacctgta tctgctttat ctgttattta tacagatgaa
    18541 ggtgcatttg atcattatct attttattct aaaaatccag atttagtttt ggttgataca
    18601 aaagttattt cacaagcccc taagcgttta ttagcgtctg gtattgcaga tggtttagca
    18661 acttgggttg aggcgcgtgc ggttatgcag gcaaatggaa aaactatgtt gggacaacag
    18721 caaacattgg ctggagttgc aattgcgaag aaatgtgaag aaacgctgtt tgcagatggt
    18781 ttacaggcta tggcagcttg tgaagctaaa gtggtgacac cagcattaga aaatattgtt
    18841 gaagctaata ctttattgag tggcctaggt tttgaaagtg gaggattagc tgcggcgcat
    18901 gcaattcata atggttttac tgcattgaca ggtgacattc atcatttaac acatggtgaa
    18961 aaagtagctt atggaacttt agtacaacta ttattggaaa atagacctaa agaagaactt
    19021 gataagtata ttgagtttta caaaaaaatt ggtatgccaa caactctaaa agaaatgcat
    19081 ttggatcaag ttggatatga tgatttaata aaagttggta aacaagcaac tatggagggt
    19141 gagacaattc atcagatgcc gtttaagatt tcgccttcag atgttgctca agctattatc
    19201 gctgtagatg cctatgtaaa ttcaaaataa acaataagga ctactgtttt ccaaatggta
    19261 gtcttttatt gatcctcgta ttgaattcta tagcagattg aaataagatg agaacaaatc
    19321 gattgggaaa gtaaaattaa tttctataag tattttagca attgtttcgt actatttcag
    19381 attcagtcca ctatacgttc ttcataaatc aaaaagcgac ataggttgtc ggctatttat
    19441 tgtgaataca ttaattagca ttccagtttt atcttcggtc taaaataagt attttgtgct
    19501 atacgagata agtttcttga cttactcctt gatttactgc ataacaatgg gataaaaagt
    19561 gggagataga gcaattcata gtcatcaaaa ttaatgagat acagtataca gtttttcctt
    19621 taaacacatt tcaaattccc tcaaaaatgg tataatagta acatcacaaa attggagaga
    19681 gaccatgagt ttttacaatc ataaagaaat tgagcctaag tggcagggct actgggcaga
    19741 acatcataca tttaagacag gaacagatgc atcaaaacct aagttttatg cgcttgatat
    19801 gttcccttat ccgtctggag ctggtctgca cgtaggacac ccagaaggtt atactgcaac
    19861 cgatatcctc agtcgttaca aacgtgcgca aggctacaat gtccttcacc caatgggttg
    19921 ggatgctttt ggtttgcctg cagagcaata cgctatggat actggtaatg acccagcaga
    19981 atttacagcg gaaaacattg ccaacttcaa acgtcaaatc aatgcgcttg gattttctta
    20041 tgactgggat cgtgaagtca acacaacaga tccaaactac tacaagtgga ctcaatggat
    20101 tttcaccaag ctttacgaaa aaggcttggc ctatgaagct gaagtgccag taaactgggt
    20161 tgaggaattg ggaactgcca ttgccaatga agaagtgctt cctgacggaa cttctgaacg
    20221 tggaggctat ccagttgtcc gcaaaccaat gcgccaatgg atgctcaaaa tcacggctta
    20281 cgcagagcgc ttgctcaatg acttagatga actagattgg tcagagtcta tcaaggatat
    20341 gcaacgcaac tggattggta aatcaactgg tgccaatgta actttcaaag taaaaggaac
    20401 agacaaggaa tttacagtct ttactactcg tccggacaca cttttcggtg cgactttcac
    20461 tgttttggct cctgaacatg aattagtaga tgccatcaca agcacagagc aagcagaagc
    20521 agtagcagac tacaaacacc aagccagcct taagtcagac ttggctcgta ccgaccttgc
    20581 caaagaaaaa actggtgtat ggactggtgc ttatgccatc aatcctgtca atggtaagga
    20641 aattccaatc tggattgcgg attacgttct tgctagctat ggtacaggtg cggtaatggc
    20701 tgtgcctgcc cacgatcaac gtgactggga atttgccaaa caatttgacc ttccaatcgt
    20761 cgaagtactt gaaggtggaa atgttgaaga agctgcctac acagaagatg gccttcacgt
    20821 taattcagac ttcctagatg gactcaacaa agaagacgct attgccaaga ttgtggcttg
    20881 gttggaagaa aaaggctgtg gacaagagaa ggtaacctac cgtctccgcg actggctctt
    20941 tagccgtcaa cgttactggg gtgagccaat cccaatcatt cattgggaag atggaacttc
    21001 aacagctgtc cctgaaagtg aattgccact tgttttgcct gtaaccaagg atatccgtcc
    21061 ctcaggtact ggtgaaagtc cactagctaa cttgacagac tggcttgaag tgactcgtga
    21121 agatggtgtc aaaggtcgtc gtgaaacaaa tactatgcca caatgggcag gttcaagctg
    21181 gtactacctc cgctatattg acccacacaa tactgagaaa ttggctgacg aggatctgct
    21241 caaacaatgg ttgccagtag atatctacgt gggtggtgcg gaacatgctg tacttcactt
    21301 gctttacgct cgtttctggc ataaattcct ctatgacctc ggtgttgttc caactaagga
    21361 accattccaa aaactcttta accaaggaat gattttggga acaagctatc gtgaccaccg
    21421 tgggggtctt gtggcgactg acaaggttga aaaacgtgat ggttctttct tccatgtgga
    21481 aacaggggaa gagttggagc aagcgccagc caagatgtct aaatcgctca agaacgttgt
    21541 caacccagac gatgtggtgg aacaatacgg tgctgatacc cttcgtgtct atgaaatgtt
    21601 catgggacca ctcgatgctt cgattgcttg gtcagaagaa ggtctggaag gaagtcgtaa
    21661 gttccttgac cgtgtttacc gtttgattag aagtaaggaa attgttgcgg aaaacaatgg
    21721 cgctcttgac aaggtttaca acgaaactgt taaagctgtc acagagcaaa ttgattccct
    21781 caaattcaac acagccattg cccaacttat ggtctttgtc aatgcggcta acaaggaaga
    21841 caagctctat gttgactatg ccaaaggatt tatccaattg attgccccat ttgcacctca
    21901 cttggcagaa gaactctggc aaactgttgc tgcaacaggt gagtcaatct cttacgtgac
    21961 ttggccaaca tgggacgaaa gtaaactggt tgaagacgaa atcgaaatcg ttgtccaaat
    22021 caaaggtaaa gtccgtgcca aactcatggt cgctaaagac ctatcacgtg aagaattgca
    22081 agaaattgct ctagcggatg aaaaagtcaa agcagaaatt gacggtaagg aaatcgtgaa
    22141 agtgattagt gtaccaaata aattggttaa tattgttgta aaataaccaa tttatttgct
    22201 gatttccaac ctcaaacagt ttcccaaact gtttgagcca actaaactcg ttaatatcgt
    22261 tgtgaaataa ggtaggaatc cttcagagta gaatctggag gattttttga atcttcttat
    22321 gaaagtatgg tatactatgg gcaactataa agtttgaaaa gtgaaaaaag gagaaagcta
    22381 tgccagtaaa tgaatatggt caaatgattg gggagtcaat ggaaggttat acaccaggtg
    22441 aactgccttc tattgatttc ttagaagggc gttatgctag gatagaggct ctttcagtgg
    22501 aaaagcatgc ggaggatttg ctagctgttt atgggcctga tacgcctcag gagatgtgga
    22561 cctacctttt tcaggagcca gtagcagata tgggggagct ggttagcctt ttacatcaga
    22621 tgttggctcg taaggaccgt ttttactatg caatcataga caaggcgact ggtaaggctt
    22681 tgggatcttt ttctctcatg cgcattgacc agaataaccg agtaatagaa gtcggagcag
    22741 tcactttttc tccagagcta aggggtacac ggataggaac tgaagctcag tatctcctag
    22801 ctcgctatgt ttttgaggag ctaaactatc gtcgctacga gtggaaatgc gatgccttaa
    22861 atctgccatc cagacgagct gcggagcgtt tgagctttat ttatgaagga accttccgtc
    22921 aggcagtggt ttataaggga cgtacgagag atacggattg gttgtctatg attgataagg
    22981 actggcctca agtcaaagat cgtttggaaa catggttgcg tcctgaaaat tttgataaaa
    23041 atggacagca gtacaagagc ttgagagaac tttaagaggt gttgagatga ttactattaa
    23101 aaagcaagaa attgtcaagc tagaggatgt tttacatctc tatcaggctg tcggttggac
    23161 aaattatacc catcaaccag agatgctgga gcaggcctta tctcattcat tagtaattta
    23221 tctggcactt gatggtgatg ctgtggtggg cttgattcgt ttggttggag atggattctc
    23281 atcagtattg gttcaggatt taatcgtttt accaatctat cagcgtcaag gaattggtag
    23341 tgccttgatg aaagaggctt tagaggatta caaagatgcc tatcaagtcc agctggtgac
    23401 agaagagaca gaaagaacct tgggcttcta tcgttctatg ggctttgaaa tcttatccac
    23461 ctataattgt atagggatga cttggatgaa tcgtaaaaaa taacaaaact tgttttttct
    23521 taagcaaaat ttaaggatgg tctagtatta tatagtcatt aaataaagac ctcctaactt
    23581 tatttaataa aatcctaaac ttttcttttt cataataatc tcccttaact ccacccaatc
    23641 aggtggagtt ttttagctct atttcaggct tttggggact attctaaaaa taatttttcg
    23701 atatttttcg gtatttttcg gattttggtc ggggaattgg cggggacttt tttagcgaat
    23761 ataactaaga aataggtctg tggtcgcttc agctagttca aactcaattt gattgtaagt
    23821 gactgttaat tgaagaactg gaactactgt aataatgatt ttgcttgtct agtagtggcg
    23881 tattaaatga gaagtgacat gtaagattgt ctcttcgttt acgaaatcaa aatttctatg
    23941 aaattgatag aatccctaac gttctcttaa tcttaaccgt cttgtcgtac agcggttgaa
    24001 gaaaatgtaa acctttgaca aaattcgtga actatgggat aataaaaagg aattgagtac
    24061 tagttctata tcataggcta gaaaagaccc caagctcacg accaaataag cttgaggtct
    24121 tttttgacac tatttgtcct tgtttagcca tttatcgact atacgaagaa cgacaccgac
    24181 cacaattggt ccgatgatag ttttgagtac taattccatc atgggctatc tcacctcctt
    24241 tcgtaggcgg tgtagcagtg tcgtagaata ttataccaca taagtgctaa acttaggagt
    24301 cacccaatca ggtggctttt ttgtttgtgg cttggttttt tgatataata gagccatgag
    24361 tagaatttta gataatgaga taatggggga tgaggagtta gtagaacgca cgctccgtcc
    24421 tcagtattta cgtgaatata tcggacagga taaggtcaag gaccagctac aaatctttat
    24481 tgaagctgcc aaaatgcggg atgaagcgct ggatcatgtg ctcttatttg ggcctccagg
    24541 tctcgggaaa acgaccatgg cctttgttat tgccaacgaa ctgggagtca atcttaagca
    24601 gacgtcgggt ccagtcattg aaaaagccgg agatctggta gctattttga atgagttaga
    24661 gcctggggat gtacttttta ttgatgagat ccatcgtttg ccaatgtcag tggaagaggt
    24721 gctttatagt gctatggagg acttctacat agatattatg attggggctg gtgagggtag
    24781 tcgtagtgtt catttggagt taccaccttt taccttgatt ggtgcgacga ctcgggctgg
    24841 tatgctctcc aatccgctac gggcacgttt tgggattaca ggccatatgg agtattatgc
    24901 ccatgctgac ttgacagaaa ttgtcgagcg gacggcagat atttttgaga tggaaatcac
    24961 tcatgaggca gcatctgagt tggccctacg tagtcgtggg acccctcgta ttgccaatcg
    25021 tctcctcaag cgcgtgcgcg attttgccca gataatgggg aatggggtaa ttgatgatat
    25081 tattaccgat aaggctttga ctatgctgga tgttgaccat gaaggtttgg actatgtgga
    25141 tcaaaaaatc cttcgtacca tgattgagat gtacagtgga ggacctgttg gtctaggaac
    25201 tctttctgtg aatatcgccg aagagcgtga gacagttgaa gatatgtatg agccttactt
    25261 gattcaaaaa ggttttatca tgcggacacg gtctggacgg gtggcgactg ctaaggcata
    25321 tgagcactta ggttatgaat acagtgaaaa ataagcaaga aatcttagag gcttttagag
    25381 aaaatccaga tatgatggcc attctgacga tcatccgaga ccttggtctg aaagactcgt
    25441 ggttggcagc aggttctgtc agaaatttca tttggaatct tttgtcagac aaatcccctt
    25501 ttgatcatga aacagatata gatgtgattt tctttgatcc agatttttct tatgaggaaa
    25561 ccttattact ggagaaaaag ctgagagagg attttcctca gtaccagtgg gaattgaaaa
    25621 atcaggtcta tatgcatcag cacagtcctc acactgcttc ctataccagt tctcgtgatg
    25681 ctatgagtaa gtatccagaa cggtgtacgg cagttggact gcgcttgaat gaagaatcag
    25741 attttgaact ctatgcacct tatggtttgg aggatatttt gaattttcaa gttcgtccaa
    25801 ctcctcattt cttagaaaat gaagaccgaa tggaactcta tcaaacacgt ttatccaaga
    25861 aaaattggca ggagaaatgg aaaaatttga tttttaaaaa tacttaagga aactttaagc
    25921 tagggagtgt acactaagtt cataagttaa gaagacctta acttaaactc ctaaaacttt
    25981 ttcataataa tctccctata aaaataaagt cgcccaatca ggcggcttat ttttttgaaa
    26041 aatgggcatg gtgcctgaga ataaatagct tagtgataga agaaaatggg gaaatatggt
    26101 ataatgaaac gatagatttt tgaataggaa taagatcatg tttggatttt ttaagaaaga
    26161 taaggctgtg gaagtagagg ttccgacaca ggttcctgct catatcggca tcatcatgga
    26221 tggcaatggc cgttgggcta aaaaacgtat gcaaccgcga gtttttggac ataaggcggg
    26281 catggaagca ttgcaaaccg tgaccaaggc agccaacaaa ctgggcgtca aggttattac
    26341 ggtctatgct ttttctacgg aaaactggac ccgtccagat caggaagtca agtttatcat
    26401 gaacttgcca gtagagtttt atgataatta tgtcccggaa ctacatgcga ataatgttaa
    26461 gattcaaatg attggggaga cagaccgcct gcctaagcaa acctttgaag ctttaaccaa
    26521 ggctgaggaa ttgactaaga acaacacagg attgattctt aattttgctc ttaactatgg
    26581 tggacgtgct gagattacac aggcgcttaa gttgatttcc caggatgttt tagatgccaa
    26641 aatcaaccca ggtgacatca cagaggaatt gattggtaac tatctcttta ctcagcattt
    26701 gcctaaggac ttacgagacc cagacttgat tatccgtact agtggagaat tacgtttgag
    26761 caattttctt ccatggcagg gagcctatag tgagctttat tttacggaca ccttatggcc
    26821 tgattttgac gaagcggcct tgcaggaagc tattcttgcc tataatcgtc gtcatcgccg
    26881 atttggagga gtttaggagg aaatatgacc caggatttac agaaaagaac cttgtttgca
    26941 gggattgccc tggctatttt cctaccaatt ttaatgattg ggggcctctt gcttcagata
    27001 gcaatcggaa tcatagccat gctagccatg catgaacttt tgaagatgag aggtctagag
    27061 accatgacga tggagggcct cttgaccctc tttgcaacct ttgcattgac cattcccttg
    27121 gagaattacc tgattttttt gccagttgat gggaatgtgg ttgcctatag tgttttgatt
    27181 tcaatcatgt taggaacgac cgtttttagc aagtcttata cgattgagga tgcggttttc
    27241 cctcttgcta tgagcttcta cgtgggcttt ggatttaatg ctttactaga tgctcgtgtt
    27301 gcaggtttgg acaaggctct cttagccttg tgtatcgtct gggcgacaga cagtggtgcc
    27361 tatcttgttg ggatgaacta tgggaaacga aagttagcac caagggtatc gcctaataaa
    27421 acccttgagg gtgccttggg tggtatttta ggagcaattt tagtaaccat tatctttatg
    27481 atagttgaca gtacagttgc tcttccatat ggaatttaca agatgtcagt ctttgctatt
    27541 ttctttagca ttgctggaca atttggtgat ttactagaaa gttcgatcaa acgtcatttt
    27601 ggtgttaagg attctgggaa atttatccct ggacatggtg gtgttttgga tcgtttcgat
    27661 agtatgttgc ttgtatttcc aatcatgcac ttatttggac tcttttaatc aaaagacgga
    27721 ggaaacgcta tgctcggaat tttaaccttt attctggttt tcgggattat tgtagtggtg
    27781 cacgagttcg ggcacttcta ctttgccaag aaatcaggga ttttagtacg tgaatttgcc
    27841 atcggtatgg gacctaaaat ttttgctcac attggcaagg atggaacggc ctataccatt
    27901 cgaatcttgc ctctgggtgg ctatgtccgc atggccggtt ggggtgatga tacaactgaa
    27961 atcaagacag gaacgcctgt tagtttgaca cttgctgatg atggtaaggt taaacgcatc
    28021 aatctctcag gtaaaaaatt ggatcaaaca gccctcccta tgcaggtgac ccagtttgat
    28081 tttgaagaca agctctttat caaaggattg gttctggaag aagaaaaaac atttgcagtg
    28141 gatcacgatg caacggttgt ggaagcagat ggtactgagg ttcggattgc acctttagat
    28201 gttcaatatc aaaatgcgac tatctggggc aaactgatta ccaattttgc aggtcctatg
    28261 aacaatttta tcttaggtgt cgttgttttt tgggttttaa tctttatgca gggtggtgtc
    28321 agagatgttg ataccaatca gttccatatc atgccccaag gtgccttggc caaggtagga
    28381 gtaccagaaa cggcacaaat taccaagatt ggctcacatg aggttagcaa ctgggaaagc
    28441 ttgatccaag ctgtggaaac agaaaccaaa gataagacgg caccgacttt ggatgtgact
    28501 atttctgaaa aggggagtga caaacaagtc actgttacac ccgaagatag tcaaggtcgt
    28561 taccttctag gtgttcaacc gggggttaag tcagattttc tatccatgtt tgtaggtggt
    28621 tttacaactg ctgctgactc agctctccga attctctcag ctctgaaaaa tctgattttc
    28681 caaccggatt tgaacaagtt gggtggacct gttgctatct ttaaggcaag tagtgatgct
    28741 gctaaaaatg gaattgaaaa tatcttgtac ttcttggcaa tgatttccat caatattggg
    28801 atttttaatc ttattccgat tccagccttg gatggtggta agattgtgct caatatccta
    28861 gaagccatcc gccgcaaacc attgaaacaa gaaattgaaa cctatgtcac cttggccgga
    28921 gtggtcatca tggttgtctt gatgattgct gtgacttgga atgacattat gcgactcttt
    28981 tttagataat cgaggaatat tatgaaacaa agtaaaatgc ctatcccaac gcttcgcgaa
    29041 atgccaagcg atgctcaagt tatcagccat gctcttatgt tgcgtgctgg ttatgttcgc
    29101 caagtttcag caggtgttta ttcttatcta ccacttgcca atcgtgtgat tgaaaaagct
    29161 aaaaacatca tgcgccaaga attcgaaaag attggtgctg ttgagatgtt ggctccagcc
    29221 cttcttagtg cagaattgtg gcgtgaatca ggtcgttacg aaacctatgg tgaagacctt
    29281 tacaaactaa aaaaccgtga aaaatcagac tttatcttag gtccaactca cgaagaaacc
    29341 tttacagcta ttgtccgtga ttctgttaaa tcttacaagc aattgccact caacctttat
    29401 caaattcagc ccaagtatcg tgatgaaaaa cgcccacgta atggacttct tcgtacacgt
    29461 gagtttatca tgaaggatgc ttatagtttc cacgctaact atgatagttt ggatagtgtt
    29521 tatgatgagt acaaagcagc ctatgagcgt attttcactc gtagtggttt agacttcaag
    29581 gctattattg gtgacggtgg agccatgggt ggtaaggata gccaagaatt tatggccatt
    29641 acatctgctc gtacagacct tgaccgctgg gttgtcttgg acaagtcagt tgcctcattt
    29701 gacgaaattc ctgcagaagt gcaagaagaa atcaaggcag aattgctcaa atggatagtc
    29761 tctggtgaag ataccattgc ttactcaagt gagtctagct atgcagctaa cttagaaatg
    29821 gcaacaaacg agtacaaacc aagcaaccgt gttgtcgctg aagaagaagt tactcgtgtt
    29881 gcaacgccag atgttaaatc aattgatgaa gttgcagctt tcctcaatgt tccagaagaa
    29941 caaacgatta aaaccctctt ctacattgca gatggtgagc ttgttgcagc ccttctagtt
    30001 ggaaatgacc aactcaacga agtcaagttg aaaaaccact taggagcaga tttctttgac
    30061 gttgctagcg aagaagaagt ggcgaatgtt gttcaagcag gatttggttc acttggacca
    30121 gttggtttgc cagagaatat taaaattatt gcagatcgta aggtgcaaga tgttcgcaat
    30181 gcagttgtcg gtgctaacga agatggctac cacttgactg gtgtgaaccc aggccgtgat
    30241 tttactgcag aatatgtgga tatccgtgaa gttcgtgagg gtgaaatttc cccagatgga
    30301 caaggtgtcc ttaactttgc gcgtggtatt gagatcggtc atattttcaa actcggaact
    30361 cgctactcag caagcatggg agcagatgtc ttggatgaaa atggtcgtgc tgtgccaatc
    30421 atcatgggat gttacggtat cggtgtcagc cgtcttcttt cagcagtgat ggagcaacac
    30481 gctcgcctct ttgttaacaa aacgccaaaa ggtgaatacc gttacgcttg gggaatcaat
    30541 ttccctaaag aattggcacc atttgatgtg catttgatta ctgtcaatgt caaggatgaa
    30601 gaagcgcaag ccttgacaga aaaacttgaa gcaagcttga tgggagctgg ttatgaagtc
    30661 ttgacagatg accgtaacga acgtgtcggt gttaaattta gcgatagtga cttgattggt
    30721 cttccaatcc gtatcactgt tggtaaaaaa gcggccgatg gcattgtaga agttaagatc
    30781 aaggcaactg gtgacaccat tgaggttcat gcagataacg tgcttgaaac gcttgaaatc
    30841 ctaagcaaga aataaaaact ataatcagaa gaaaaacaag gaaaaaatgt aactagtttt
    30901 taccttgttt tttctgtata atgggagaaa tgagtagata aagaggtaaa tgttatgcta
    30961 agatttccaa aggattttgt ctggggatcc tctacttctg gaccgcagac agaaggacgt
    31021 gtagctggtg acggtaaggg agacaatctc tgggattact ggttccaagt ggagccaaat
    31081 cgttactata atgggattgg ttcagataag acatcgactt tttatgaaaa ttgggagcgg
    31141 gatattgagc ttttgttaga gactggtcac acagtctttc ggacttctat tcagtggtca
    31201 cggatttttc cacaaggctg tggaaaagtc aaccctcaag gtgtggattt ttatcgtaag
    31261 gtctttgagg ctattaaggc taaaggaatt cgtctgttag tcaatctcta tcattttgat
    31321 ttaccttttg cccttcaaga ggatggtgat ggttgggaaa ataaggcgac agtctcagcc
    31381 tatgaagact atgctcgttt ttgttttgag acttatggag atttagtgga tcaatggatt
    31441 acctttaacg agcccatcgt tcctgtagaa tttggttatt tttatgatgc ccattatcca
    31501 cataaggtgg atgcagaggc agctgttaag gtagcctatc atacacaatt ggccagcagc
    31561 cgggctgtta aggcttgcca tgaacttttg cctgattcca agattgggat tgtcctcaac
    31621 ttgacaccgg cttatccacg tagccagcat cctgctgatg tcaaggcagc tcgtattgcg
    31681 gccctttttc aggcccaatc tttcttagat ccatctgtct tggggactta tccacaggag
    31741 ttggtagaaa tcttgcatga acacggtctt ttacctgatg ctacagagga agagttggaa
    31801 ctcattcatg ataatacggt ggacttcctt ggtgtgaact actatcaacc tttgcgtgtt
    31861 atggctcctc gatttgctaa gcatccagag agtccactct taccagaaca tttttacgag
    31921 ccttatgtga tgcctggacg taaaatcaat tctcaccgtg gttgggagat ttatgagcaa
    31981 gggatttatg acatcgccca aaatatcaag gaaaattatg gcaatattga atggatgttg
    32041 actgagaatg gtatgggtgt tgaaggggaa gaaaaattcc gtcaagatgg aatgattcaa
    32101 gatgattacc gtattgactt tgtaaaaggt catcttcgtg aacttcaccg tgccattgaa
    32161 gatggtgcca actgtaaggg ctacttgatt tggaccttta ttgactgctg gtcatggctc
    32221 aacagctata aaaatcgcta tggtttggtc gaattagact tggaaacgca agaacgtcgt
    32281 ctgaagaaat caggccactg gttcaaaaaa ttaagcgata ataatggatt ttaaaaagga
    32341 ctctgactga ttatcccaat cggtcagagt tttttgctta caggagctta atttgaacta
    32401 taccaatttt tactcttgac aagtgaaaga aacaagtata tactgttttt gctgattcta
    32461 taaaagatga attagactat accaatttta aggagaaagc acagcttgcc tgtgtcgtat
    32521 atactatgtg tggaattgtt ggtgttgttg gaaacacaaa tgcaactgat attttgattc
    32581 aagggcttga aaagcttgaa taccgtggct atgattctgc gggaattttt gtcctagatg
    32641 gtgctgataa ccatttggtg aaggctgttg gtcgtatcgc agaattgtct gccaagacag
    32701 ctggtgttga gggaacaact ggtatcggac atactcgttg ggcaactcat gggaaaccaa
    32761 cggaagacaa tgctcaccca caccgctctg agacagaacg ttttgtcttg gttcacaatg
    32821 gggtgattga aaactacctt gaaattaaag aagaatacct tgctgggcac cacttcaaag
    32881 ggcaaacaga tacggaaatc gccgtacatt tgattggaaa atttgcggaa gaagacggtc
    32941 tctcagttct tgaagccttt aaaaaagctc ttcatattat ccgtggttca tatgcctttg
    33001 ccttgattga ctctgaaaat ccagatgtca tctatgtagc gaaaaacaaa tctccacttt
    33061 tgattggtct tggggaaggc tacaatatgg tctgctcaga tgctatggct atgattcgtg
    33121 aaaccaacca atacatggaa attcatgacc aagagttggt aatcgtcaag gctgatagcg
    33181 tggaagttca agactatgat ggaaatcgtc gtgagcgtgc tagctacact gctgaacttg
    33241 acttgtcaga tatcggtaag ggaacttacc cttactacat gctcaaggaa attgacgagc
    33301 aaccaactgt tatgcggaaa ctcatccaag cctacacaga tgaggctggt caagttgtcg
    33361 tagacccaga tatcattaag gctgttcaag acgcagaccg catctacatc cttgcagctg
    33421 gaacatctta ccatgcagga tttgcttcta agaagatgtt ggaagaattg acagatacac
    33481 cagttgaact tggaatctca tctgagtggg gctacggtat gccacttctc agcaagaaac
    33541 cactcttcat ctttatcagc caatctggtg aaacagcgga tagtcgtcaa gttttggtca
    33601 aggctaatga aatgggaatt ccaagcttaa cagtgacaaa tgttccaggt tcaaccctct
    33661 cacgtgaagc caactatacc atgctccttc acgcaggtcc tgaaattgcc gtggcatcaa
    33721 ctaaagccta tacagcgcaa atcgcagccc ttgccttcct tgcaaaagca gtcggagaag
    33781 caaatggtaa tgctaaagcg caagcctttg acctggttca tgaattgtca atcgtagctc
    33841 agtctattga atcaactctt tcagagaaag aaaccattga agccaaggtt cgtgaacttc
    33901 ttgaaacaac tcgtaacgcc ttttacatcg gacgtggtca agattattac gtagccatgg
    33961 aagcaagtct caaactcaaa gagatttctt atatccagtg tgaaggtttt gcggcaggag
    34021 aactcaagca cggaaccatt gccttgattg aagaaggaac gcctgttttg gctctcttgt
    34081 cagatccagt tcttgccaac catactcgtg gaaatatcca agaggtcgca gcccgtggtg
    34141 ccaaagtcct cactatcgca gaagagaatg tagccaaaga taccgacgat atcgtcctta
    34201 cgaccgtaca tccatacctc tcaccaattt caatggtcgt accaacgcaa ttagtcgctt
    34261 actttgcaac cctccaccgt ggcctcgatg tggacaaacc acgtaacctt gccaagtcag
    34321 taacggtaga ataagctaaa aaagtctagt tatctaggct ttttcttgtg agcaaattgg
    34381 ttgcttgtac tcaagattcg tgttatactc ttagaaaatc tcttcaaacc acgtcaccgt
    34441 cgccttgccg taggtatggt tactga
//
LOCUS       DAVBIC010000020        34347 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.020, whole genome shotgun sequence.
ACCESSION   DAVBIC010000020 DAVBIC010000000
VERSION     DAVBIC010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34347)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34347)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34347
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.020"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            <1..4786
                     /locus_tag="VQ664_000927"
     CDS             <1..4786
                     /locus_tag="VQ664_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HET2789109.1"
                     /translation="QGERGLTGAKGEKGDQGERGLTGAQGEKGDRGERGLTGAKGEKG
                     AQGQAGRDGVTPTVTVKDNKNDGTHTITINDGRGNVTSTVVRDGFDGASPLVATQRND
                     ADKTTTVIFYYDKNGNNELDASDKKLKEVVIADGAKGEKGDKGEQGLQGRDGEQGPKG
                     EDGKTPTVKVTDGQDGTHTITINDGKGGITTTVVRDGFDGASPLVSTHRNEADKTTTV
                     IFYYDLNDNNQFDEGDTKLKEVVIADGKQGPKGDKGDNGKDGFTPEVTVTDNNNGTHT
                     ITITQPDNRPSLTTIVKNGEDGKTPKVKAERDDAKKQTTLTFYIDKDGDGSYTAGKDE
                     LVQTTVVKDGQDGAAGASGRDGKEVLNGKVDPTTEGKDGDTFVNTQTGDVFVKKGNTW
                     EPAGNIKGPKGDKGADGAKGEKGAQGERGLTGAQGVKGEKGDQGERGLTGSKGEKGDQ
                     GERGLTGAQGAKGDKGEQGLQGRDGAQGPKGADGQRGPAGPQGPKGEQGNPGTPGKDG
                     KSLIAVKNGTETKVYVEDPARPGQPLNPNQPLATITDGRNGTNGQSPTITATRSVQNG
                     KNGVLVTITPVGGRPQTTFVEDGQKGADGKTPTVTITEGQNGTHTLTVHNPGSPDVTT
                     TIRDGATGQAGRDGKDVLNGKVNPQPNQGKNGDKYINTETGDVYVKNNGNWDKEGNIK
                     GPKGDKGADGAKGEKGDQGERGLTGAQGAKGADGAVGRDGRDGKDVLNGKANPEAHQG
                     KDGDKYVNTETGDVFVKNNGNWDKEGNIKGPKGDKGERGEDGKTPEVTVTPGKDGHST
                     DITFTVPGKDPVTVNVKDGENGLNGKTPKVDLLRVQGKNGNPSHTIVTFYTDENNDGK
                     YTPGTDELLGSEMIKDGAKGADGRDGKSLLTVKDGKETKVYQEDPANPGQPLNPEKPL
                     AVIRDGVDGKSPTVTAVRKDEAGHKGVEITVDNHDGSQPTTVFVQDGAKGETGATGQD
                     GQTPTITTQRGQDGQSTVVTITTSGKDPVTFTVKDGKNGKDGRAPKIKVEDITSPSRI
                     RRDTDAAATPTRNGIRVTVYDDVNDNGVYDEGVDKVLNSKDIYNGIDGRDGSAPTITT
                     KDNGDGTHTITVQNPDGSESTTVVKDGKDGKTANITTTENPDGSHTITVTNPDGSTKE
                     TVVKNGKDGKTPKVEVTDNNDGTHTVKVTDGDGNVTNAIIKDGKDGKAATATTTENPD
                     GSHTVTITNPDGTKNEFVVKNGRDGVDGRTPTASVRDNGDGSHTIVITNPEGVTTETT
                     VRDGKSPKVTITDEQNGTHKISVLNGDGTTTTTTVRDGREPKLEVIDNNDGSHTIKVT
                     GADGKGTTTTIFDGKSPKANIVDNGDGTHTLTIVDSDGREYKSIIKDGKDGKDSVSPT
                     VTVKNNNDGTHVVTITNPDGSKTEMVIKDGKDGKSPKVSVEDNGDGSHTITIINSDGT
                     VTKTVIKDGRDGRDGRDGKDGKDGKDGKCGCQDKPVTPSNDKPVPPTPNVPTPEVPVK
                     PVPAQPTPNVPTPEVPVQPTPAVPTPEVPVKPVPAVPEQPVVPTPAQPATPVNANPVA
                     PTTGKENRGDKLPETGSQSDYISVLLGSGILLSLYVGRRKEA"
     gene            complement(5023..5571)
                     /locus_tag="VQ664_000928"
     CDS             complement(5023..5571)
                     /locus_tag="VQ664_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HET2789110.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGVSALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIQ"
     gene            5892..6380
                     /locus_tag="VQ664_000929"
     CDS             5892..6380
                     /locus_tag="VQ664_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HET2789111.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISASFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQADQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGVSQEKAETVSKEKGAGEIDKIIFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GL"
     gene            6377..7564
                     /locus_tag="VQ664_000930"
     CDS             6377..7564
                     /locus_tag="VQ664_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET2789112.1"
                     /translation="MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAAVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSAKEDNHFKVTVEQLEAA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTVILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            7557..7922
                     /locus_tag="VQ664_000931"
     CDS             7557..7922
                     /locus_tag="VQ664_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET2789113.1"
                     /translation="MIDHFEIKVKDLQISEGFYRSFLAPLDYKLAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEVQACYEAGLEAGGRDNGAPGYRSEHPIYY
                     AAFMIDLDGNNIEVVCHKE"
     gene            7938..9284
                     /gene="asnS"
                     /locus_tag="VQ664_000932"
     CDS             7938..9284
                     /gene="asnS"
                     /locus_tag="VQ664_000932"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HET2789114.1"
                     /translation="MMTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            9437..9727
                     /locus_tag="VQ664_000933"
     CDS             9437..9727
                     /locus_tag="VQ664_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HET2789115.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            9739..10209
                     /gene="ssbA"
                     /locus_tag="VQ664_000934"
     CDS             9739..10209
                     /gene="ssbA"
                     /locus_tag="VQ664_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HET2789116.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            10241..10480
                     /locus_tag="VQ664_000935"
     CDS             10241..10480
                     /locus_tag="VQ664_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HET2789117.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            10775..12175
                     /locus_tag="VQ664_000936"
     CDS             10775..12175
                     /locus_tag="VQ664_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HET2789118.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSYVEEYI
                     SWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFDALEVFGMVEKELHFPQV
                     DIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDVIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            12177..12536
                     /locus_tag="VQ664_000937"
     CDS             12177..12536
                     /locus_tag="VQ664_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HET2789119.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKKK"
     gene            12590..13339
                     /locus_tag="VQ664_000938"
     CDS             12590..13339
                     /locus_tag="VQ664_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HET2789120.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVDPYSNLNESEHYLLARHEITTNLEEICHSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            13329..13628
                     /locus_tag="VQ664_000939"
     CDS             13329..13628
                     /locus_tag="VQ664_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HET2789121.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDMRRRLAIHNSGKGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALFKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            13699..14634
                     /locus_tag="VQ664_000940"
     CDS             13699..14634
                     /locus_tag="VQ664_000940"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HET2789122.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            14721..15233
                     /locus_tag="VQ664_000941"
     CDS             14721..15233
                     /locus_tag="VQ664_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoylalanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HET2789123.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGAVCQEPADFFESNHLYDLYVYPEMDIQSVKERACRHLGAPYNASFYPDAAGFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERNLHDSDF"
     gene            15270..15865
                     /locus_tag="VQ664_000942"
                     /pseudo
     CDS             15270..15865
                     /locus_tag="VQ664_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809149.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
     gene            15966..16160
                     /locus_tag="VQ664_000943"
     CDS             15966..16160
                     /locus_tag="VQ664_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HET2789124.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     EDAKGAVEGAVEGLKNVFTK"
     gene            complement(16206..17651)
                     /locus_tag="VQ664_000944"
     CDS             complement(16206..17651)
                     /locus_tag="VQ664_000944"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HET2789125.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVIFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYVAEKDYEVDIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKLLAFTGTKGKTTATYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQAYLVHRVYGLTFDVGVFLNITPDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVIINSDMDHFSVLKEQVEDQDHDFYGSQFDNQIENSKA
                     FSFSATGKLAGDYDIQLIGNFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMAIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGADCYQIIQGKKESYPGDTAVAENYL"
     gene            17757..19379
                     /locus_tag="VQ664_000945"
     CDS             17757..19379
                     /locus_tag="VQ664_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HET2789126.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLALGLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            19583..21541
                     /locus_tag="VQ664_000946"
     CDS             19583..21541
                     /locus_tag="VQ664_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2789127.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
                     KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFL
                     MKALVSKSAIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFP
                     NSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNK
                     NFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVASKMVNYG
                     KEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGV
                     SSIKQSIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYHGGWGPDYQDPS
                     TYLDIFNTNSGGFLQNLGLEPGEANDKAKAVGLDVYTQMLEEANKEQDPAKRYEKYAD
                     IQAWLIDSSLVLPSVSRGGTPSLRRTVPFATAYGLTGTKGVESYKYLKVQDKIVTTDE
                     YAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            21713..22648
                     /locus_tag="VQ664_000947"
     CDS             21713..22648
                     /locus_tag="VQ664_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2789128.1"
                     /translation="MKLKLLRVDTKVIMGSFLLVLSSLLALLLPLILKGLIDGSSIEN
                     IGSKVFQSFLIFIGQALFSSIGYYLFSQSGEKKIAKIRKKVIEGLIYAEKSFFDKSQS
                     GELTSAIVNDTSVIREFLITTFPNIILSLVMVLGSIVVLFSLDWNLSLLLFITLPCMM
                     FIILLLSNISEKYSRRLQEEIGFLTGQLTEKIQEHELIKTNQAEKSVQDVLDNCIERV
                     QNNSLKSDRVTSFETPFALLFIFATIAVMLTYGGYRVSAGYISVGTLVSFLIYLFQLL
                     NPISNIANFVTVYSRSKGSSVALENLLAVPKEKFE"
     gene            22673..23325
                     /locus_tag="VQ664_000948"
                     /pseudo
     CDS             22673..23325
                     /locus_tag="VQ664_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864981.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            23483..24577
                     /locus_tag="VQ664_000949"
     CDS             23483..24577
                     /locus_tag="VQ664_000949"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HET2789129.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLAAIESADYALATSSGMSAIVLAFSVFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGRFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDARDLIADLRQALEG"
     gene            24585..25751
                     /locus_tag="VQ664_000950"
     CDS             24585..25751
                     /locus_tag="VQ664_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET2789130.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IRQAVQTYADQLVYGYTYASEDLIKEIQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDGLFEIDFDQLEKDLVEEE
                     VKLYILCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVVDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVATFAKR"
     gene            25844..28942
                     /locus_tag="VQ664_000951"
     CDS             25844..28942
                     /locus_tag="VQ664_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET2789131.1"
                     /translation="MAKLIPGKIRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLVFCACDSFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLNRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINSQKYYVIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVPDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADANLFAFTVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKALPVGQQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQNIAQEEIDQAMQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPLQATQVKADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVAVVHGLKASREEILAESHQIYVTSY
                     ATFRQDSEFYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQ
                     GASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELPDLGLTSFKITGSTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLTGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            28990..29607
                     /locus_tag="VQ664_000952"
     CDS             28990..29607
                     /locus_tag="VQ664_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HET2789132.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPIAEEKPVKPIEKQVGKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTTPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            29617..30951
                     /locus_tag="VQ664_000953"
     CDS             29617..30951
                     /locus_tag="VQ664_000953"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HET2789133.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEAEGNDFVASDLLRSTTGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFSGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            30961..31425
                     /locus_tag="VQ664_000954"
     CDS             30961..31425
                     /locus_tag="VQ664_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2789134.1"
                     /translation="MEIPIKIIQASKSDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQYLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     DLDYKGIRLESPDELLSYFEMNGFVDEEATLLYATSQGYSMIWFNPFYLEEQ"
     gene            31422..31916
                     /locus_tag="VQ664_000955"
     CDS             31422..31916
                     /locus_tag="VQ664_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2789135.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            31997..33646
                     /gene="mltG"
                     /locus_tag="VQ664_000956"
     CDS             31997..33646
                     /gene="mltG"
                     /locus_tag="VQ664_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HET2789136.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSAEELMTDSLSTVEEIMRKAPTVPTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPTPATETVDIIS
                     DTSRRSRREGAKPVNPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPIDA
                     NSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQKSM
                     STEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQAVGQLQGDFKESLTAEAFLA
                     KVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDEML
                     AAMDKNLSPYYSTIKSKNLTVNELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDMPL
                     QSNIAILYAQGKLGQNISLAEDVAIDTNIDSPYNVYKNVGLMPGPVDSPSLDAIESSI
                     NQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            33717..34199
                     /gene="greA"
                     /locus_tag="VQ664_000957"
     CDS             33717..34199
                     /gene="greA"
                     /locus_tag="VQ664_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HET2789137.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
BASE COUNT        10715 a         6373 c         7776 g         9483 t
ORIGIN      
        1 ccaaggtgaa cgcggtttaa ctggagctaa aggtgaaaaa ggggaccaag gtgaacgcgg
       61 tctcactgga gcccaaggtg aaaaaggaga ccgaggcgaa cgtggtttaa ctggagctaa
      121 aggtgaaaaa ggagcccaag gtcaggcagg tcgtgacggt gtaactccaa ccgtaaccgt
      181 taaagataat aaaaatgacg gcactcatac tatcactatt aacgacggta gaggtaatgt
      241 tacaagtact gttgtaagag atggtttcga tggcgcaagt ccattagttg cgactcaacg
      301 aaatgacgca gataagacaa caactgttat cttctattac gataaaaatg gaaacaatga
      361 attagatgct tctgataaga aattaaaaga agttgtaatt gcagatggtg ctaaaggtga
      421 aaaaggggac aaaggtgaac aaggtcttca agggcgtgat ggtgaacaag gaccaaaagg
      481 agaagatggg aaaaccccaa cagttaaagt aactgatggt caagatggaa cgcatacaat
      541 tacaattaac gatggtaaag gtggtataac tactacagta gtaagagatg gatttgatgg
      601 tgcaagccct cttgtttcta ctcatagaaa tgaagcagat aaaacaacaa ctgttatttt
      661 ctattatgat ctaaatgata ataatcaatt tgatgaagga gatacaaaac ttaaagaagt
      721 tgttatcgca gatggaaaac aaggaccaaa aggtgacaaa ggtgataacg gaaaagatgg
      781 attcacacca gaagtaacag ttacagataa caataacgga acacacacca tcacaatcac
      841 acaaccagac aacagaccat cattaacaac aatcgttaaa aacggtgaag atggaaaaac
      901 accaaaagtc aaagcagaac gagatgatgc gaagaaacaa acaacattaa cattctacat
      961 tgacaaagat ggagatggaa gttacacagc aggaaaagac gagttagttc aaacaacagt
     1021 agttaaagac ggacaagacg gagctgcagg agcatctgga cgtgatggaa aagaagtatt
     1081 aaacggaaaa gtagacccaa caacagaagg taaagatgga gacacattcg taaatacaca
     1141 aacaggagat gtattcgtta agaaaggtaa cacttgggaa ccagcaggaa acatcaaagg
     1201 accgaaaggt gacaaaggtg cagatggtgc caagggtgaa aaaggagccc aaggagaacg
     1261 cggcctgact ggagcgcaag gtgtcaaggg tgaaaaggga gatcagggtg aacgcggtct
     1321 aactggatct aaaggtgaaa aaggagacca aggtgaacgc ggtttaactg gagcgcaagg
     1381 tgccaaaggt gacaaaggtg aacaaggtct tcaaggtcgt gatggagctc aaggaccaaa
     1441 aggcgcagat ggacaaagag gaccagcggg accacaagga ccaaaaggag aacaaggtaa
     1501 tccaggaact ccaggtaaag atggaaaatc tctaattgct gttaaaaatg gaactgaaac
     1561 aaaagtctat gtagaggatc cggctagacc aggacaacca cttaatccaa accaaccatt
     1621 agcaactatc actgatggaa gaaacggtac taatggacaa tcaccaacaa ttacagcgac
     1681 acgaagtgtg caaaatggca aaaatggtgt attagtaaca attacaccag taggaggtcg
     1741 tccacaaaca acatttgtag aggatggaca aaagggtgct gatgggaaaa ccccaacagt
     1801 aacaataact gaggggcaaa acggcacaca tacattaacg gttcataatc caggaagtcc
     1861 agatgtgaca actacgatcc gtgatggagc tacaggacaa gcaggtcgtg atggtaaaga
     1921 tgtattaaac ggaaaagtaa atccacaacc aaaccaaggt aaaaatggag ataaatatat
     1981 taataccgaa accggtgatg tctatgttaa aaacaatgga aactgggata aagaaggcaa
     2041 catcaaaggc cctaaagggg acaaaggtgc agatggtgct aaaggcgaaa aaggagacca
     2101 aggcgaacgc ggcctaactg gagcgcaagg agctaaaggt gcggatggcg cagtaggtcg
     2161 tgatggacgt gacggtaaag acgtgttgaa cggcaaagct aacccagaag cacatcaagg
     2221 taaagacggc gataaatacg ttaatacaga aacaggcgac gtcttcgtta agaataacgg
     2281 caactgggat aaagagggca acatcaaagg ccctaagggt gacaaaggtg aacgcggaga
     2341 agatggtaag actccagaag taactgtaac tccaggtaaa gatggccata gtactgacat
     2401 tacattcact gttccaggta aagatccagt tacagtaaat gttaaggacg gagaaaatgg
     2461 tctgaacggt aaaactccaa aagttgattt acttcgtgtc caaggaaaaa acggaaatcc
     2521 atctcataca attgtgacat tctatacaga tgaaaacaat gacggcaaat atacaccagg
     2581 aactgatgaa cttctaggtt cagaaatgat taaagatggt gctaaaggcg cggacggacg
     2641 agatggtaaa tcattgctta ctgtcaagga tggtaaagaa actaaagttt accaagaaga
     2701 tccagctaac ccaggacaac cattaaatcc agaaaaacca cttgcggtaa ttagagatgg
     2761 agtagatgga aaatcaccta cagttacagc tgttcgtaaa gatgaagcag ggcataaagg
     2821 tgtagaaatc actgttgata accatgatgg ttcacaacca actacagtct ttgttcaaga
     2881 tggtgctaag ggagaaactg gtgcaaccgg tcaggatgga caaactccta caatcactac
     2941 tcaacgtgga caagatggcc aaagcactgt tgtaactatc acaacatcag gtaaagatcc
     3001 agtaaccttc actgtaaaag atggtaagaa tggtaaagat ggccgtgcac cgaaaatcaa
     3061 agtagaagat attacttcac cttcaagaat tagacgcgat acagatgctg ctgcaactcc
     3121 aacgcgtaac ggtatccgtg ttacagttta tgatgatgtt aatgacaatg gggtatacga
     3181 cgaaggtgtc gataaagtat taaatagtaa agatatttat aacggtatag atggacgtga
     3241 tggttcagct ccaactatta ctacaaaaga taatggagat ggaactcaca ctatcacagt
     3301 tcaaaaccca gatggttctg aatcaacaac agttgttaaa gatggtaaag acggtaaaac
     3361 tgcgaatatc actacaacag aaaacccaga tggaagccac acaattacgg tgacaaatcc
     3421 agatggttca actaaagaaa ctgttgttaa aaacggtaaa gacggtaaga ctcctaaagt
     3481 tgaagtaacg gataacaacg atggaactca tactgttaaa gttacagatg gagacggcaa
     3541 tgttaccaac gctatcatca aagatggtaa agacggtaaa gctgcaacag caacaactac
     3601 tgaaaatcca gatggaagcc acacagtaac aatcactaac ccagacggaa ctaagaatga
     3661 gtttgttgtt aagaatggac gtgacggtgt tgacggacgt actccaaccg catctgttcg
     3721 tgataatgga gacggaagtc atacaatcgt tattacaaat ccagaaggtg tgacaactga
     3781 aaccacagtt cgtgatggta aatcaccaaa agtgactata actgatgaac aaaatggaac
     3841 tcataagatc tctgttctaa atggtgacgg aacaactaca acaactacag ttcgtgatgg
     3901 tagagaacca aaacttgaag ttattgataa caacgatggt tcacacacta ttaaagtgac
     3961 aggtgctgat ggtaaaggaa cgacaactac aatctttgat ggtaaatcac caaaagcgaa
     4021 catcgttgat aacggagatg gaactcatac attaacaatc gtagattctg atggtcgtga
     4081 atacaaatct attatcaaag atggtaaaga cggcaaagat agcgtttcac caactgtaac
     4141 tgttaaaaat aataacgatg gaactcacgt tgttacaatc actaatccag atggaagtaa
     4201 gacagaaatg gtgattaaag acggtaaaga tggtaaatca ccaaaagttt ctgttgaaga
     4261 taatggtgat ggtagtcata caatcacaat catcaattct gatggaactg tgacaaaaac
     4321 agttattaaa gatggtagag atggacgtga tggtcgagac ggcaaagacg gtaaagacgg
     4381 taaagatgga aaatgtggat gccaagacaa accagtaaca ccatcaaatg acaaaccagt
     4441 tcctccaaca ccaaatgtgc cgacaccaga agtaccggtt aaacctgtgc cagcgcaacc
     4501 aacaccaaat gtaccgacac cagaagtgcc agtacaacca actccagctg ttccaacacc
     4561 agaagtaccg gttaaaccag taccagcggt tccagaacaa ccagtagtac caacaccggc
     4621 tcaaccagca actccagtaa atgctaaccc agtagcacca actacaggta aagaaaaccg
     4681 tggggacaaa ttacctgaaa ctggaagcca atctgattat atctctgttc ttttaggtag
     4741 cggtattcta ttgagcctat atgtaggacg aagaaaagaa gcttaatcag ccaaaagcag
     4801 tcactaattt ctcgaaagaa gatgataagt gatagatctc gaatgaaaga atattcttag
     4861 aatgattttc ctatgatgga aaagactgct aaaaaccttg agtggtaacg ctcaaggttt
     4921 ttttggatgg ctgatgtttg tctgaaaatc ttgattgaga aataaaaagc caccctatta
     4981 ggtggctata attgatttag actttctaaa attttctatt ttttactgaa tcgcttcgac
     5041 caagtcttga gcttgttttt caagtgagtt taggactgtt tcttcaagaa ccaattttcc
     5101 gtctgcccag gcagagtcat taacacgtgc agcagtgaaa tcaccaacgc cttgtgtacg
     5161 gataaatggc aagaggtctt tgtagatagc gaaaagttga tcgtgccctg cattggctac
     5221 agatgatacg gtgacaaact tgtcttgaag ggcagaaacg ccacgcgtat cagacaagtc
     5281 aagggcacga gatagccagt caagcaagtt ttttactgta ccagggatag agaagttgta
     5341 gactggagag aaaatccaga tagcatccgc aacgagaact gcttcacgag cagcagctac
     5401 agctggatgt gttggaactt ccaaatcttg gctgaagaga ggaagggctg aataatcaag
     5461 gtagctaact tccgctttac cagcaagtgc tttctcagct tcgagcgcca tttggtggtt
     5521 gaaagaacct tgacgtagtg atccgacgat aaataatact tttttagaca tgatgtgtct
     5581 cctttttctt caaattttga gaactctctc gttgttataa aatacattac aacaaaacaa
     5641 aagaacttgc aagaaatttg ctcagagttt atttgaaaat tgtaaaattt cggaaactct
     5701 agtcatttgt gactgaaaaa gtaagaactg tttcactttc aaaatcggtt ttgtttgaag
     5761 ggagaaatag aattggttgc tcaaagcaca gctttgaggt tgcagataaa gctgacgtgg
     5821 tttgaagaga ttttcgaaga gtattcttat attcacttgt aataaagctt aatagatggt
     5881 aaaatagacg agtgaaaaaa agacaaaaca aagcaaaaaa taatctactg tggcagtatg
     5941 gtctagggat gacgattttg tttgtggtta tcagtgcttc ctttctgtat atggtttctc
     6001 ttagcatgaa accctatcaa acagctaaaa gtgaaggaga aaaattagct cagcagtatg
     6061 caggattaga gcaggccgat caggttgatt tatacaatgg cttggaatct tattacagcg
     6121 ttcttggtcg taataaacag caagaagcac ttgctgttct gattggaaaa gatgatcata
     6181 agatttacgt ttatcagcta aatcagggtg tttcacaaga aaaagcagaa acggtttcta
     6241 aggaaaaggg agctggcgaa attgacaaga ttatctttgg tcgttatcaa gataagccaa
     6301 tctgggaagt caagtcagga tctgattttt atctagtaga ttttgaaaca ggagcattgg
     6361 tcaacaagga gggcctatga aattatccaa ccgtgtttta gaaatggaag aaagtgtgac
     6421 tttggctgct ggagcccgtg ccaaagcact gaaggctgag ggtagagata ttttgtctct
     6481 aaccttgggt gagccagatt tcactactcc caaaaatatc caagatgccg ccattgcatc
     6541 gattcgagat gggcgtgctt ctttttatac agtaacctca ggtctgccag agcttaaggc
     6601 ggcggtcaat agctactttg agcgctttta cggctattct gtagcgtcaa atcaagtgac
     6661 agtcgctgcg ggagccaaat attctctcta taccttcttt atggctgtgg tcaatccagg
     6721 tgatgaagtc atcatcccaa ccccatactg ggttagctat ggagatcagg tcaagatggc
     6781 agaaggcgtt cccgtctttg tttctgctaa ggaagacaat cactttaagg tgaccgtaga
     6841 gcagttagaa gcagctcgca ctgacaagac caaggttttg gtgctgaatt cgccatctaa
     6901 tcccacaggt atgatttaca cccgtgagga actcttggca attggaaact gggctgtaga
     6961 aaatgatatt ctcatcctag cagatgatat ctatggccgc ttggtttata atggtcatga
     7021 gttcacaccg atttctagcc tatcggaagc gattcgcaag caaacagtgg tcatcaatgg
     7081 tgtgtctaaa acctatgcca tgactggttg gcggattggt tatgccgttg gagaagcaga
     7141 cattatcgct gccatgtcca agattgcagg tcaaacaact tcgaatccgt cagcagtagc
     7201 ccaatatgca gcagttgagg ctctatcagg tgagcaagat actgtagaaa gcatgcgtca
     7261 ggcctttgaa gaacgtctta ataccatcta tcccctcctt gcagaagtgc caggatttga
     7321 agtggtcaaa ccgcaagggg ccttctatct cttcccaaat gtcaaaaagg ccatggagat
     7381 gaaaggctac acggatgtga cagactttac aactgttatc ttagaagaag ccgaagtggc
     7441 cttggtaaca ggagctggat ttggagcacc agaaaatgtc cgcctcagct atgcgacaga
     7501 cctagacacg cttaaagaag cagtcgaacg cttgaaagca tttatgggta gtgagaatga
     7561 ttgatcattt tgagattaag gtaaaggatt tacaaatttc agaaggattt tataggagtt
     7621 ttctcgctcc tttggactat aaattggctt ttaagactag ttctctaatt agttttctat
     7681 ccccgaacag ccctcatcct ggtggtgatt tttggctgac tcagggaaca caagatcctg
     7741 ttcattttgc ttttttagca gaaaataagg aagaagttca ggcttgttat gaggctggct
     7801 tagaggcagg tgggcgagac aatggggctc ctggttatcg aagtgagcat ccgatttact
     7861 atgctgcttt tatgattgac ctggatggga acaatataga ggtggtttgc cataaagaat
     7921 aaaaaagaaa aggaaaaata atgacaaaac gtgtaacgat tattgacgta aaagactatg
     7981 ttggtcagga agtgacgatt ggcgcttggg ttgccaacaa atcaggaaaa gggaaaatcg
     8041 ctttcttaca attgcgtgat ggaacagcct tctttcaagg tgtggctttt aaaccaaact
     8101 ttgtcgaaaa atttggtgaa gaagtgggac ttgagaagtt tgatgttatc aaacgcttga
     8161 gccaagaaac gtctgtttat gtgacaggta ttgtcaaaga ggacgaacgt tctaaatttg
     8221 gctatgagtt ggacatcaca gacatcgaag tgatcggtga atctcaagac tacccaatca
     8281 caccaaaaga acacggaaca gactttttga tggataaccg tcacttgtgg ctacgctctc
     8341 gtaagcaagt agctgtgttg caaatccgta acgctattat ctatgcaact tatgagttct
     8401 ttgacaagaa cggttttatg aagtttgaca gcccaattct ttcaggaaat gcggcagaag
     8461 attctacaga actctttgaa actgactact tcggaacgcc agcctacttg agccaatcag
     8521 gtcaacttta cctagaagca ggggctatgg ctcttggtcg tgtctttgac tttggtccag
     8581 ttttccgtgc tgaaaaatca aaaacacgcc gtcacttgac tgagttctgg atgatggatg
     8641 ctgagtactc atacttgaca catgatgagt cgcttgactt gcaagaagct tatgtgaaag
     8701 ctcttctaca aggtgttctt gaccgcgcgc ctcaagcctt ggaaaccttg gaacgtgata
     8761 cagaactctt gaaacgctac attgcagagc cattcaaacg tatcacttac gatcaagcca
     8821 ttgacctctt gcaagagcat gaaaatgatg aagatgctga ctacgagcat cttgagcatg
     8881 gtgatgactt tgggtcacca cacgaaactt ggatttcaaa ccactttggt gtgccaacat
     8941 ttgtcatgaa ctatccagca gccatcaagg ccttctacat gaaaccagtt cctggaaatc
     9001 cagagcgcgt gctttgtgca gacttgcttg ctccagaagg ctatggagaa attatcggtg
     9061 ggtctatgcg tgaggaagat tacgatgccc ttgtcgctaa gatggatgaa cttggcatgg
     9121 atcgtacaga atatgaattc taccttgacc ttcgtaaata cggtacagtt ccacacggag
     9181 gatttggtat cggtatcgaa cgtatggtaa ccttcgcagc aggaacaaaa catatccgtg
     9241 aagctattcc attcccacgt atgttgcacc gtatcaaacc ataagaacag gaaaacgccc
     9301 atgtggcgtt ttttcgaatt ctagtgtttt tacttgcgta aaaaaaattt ttctagtata
     9361 atagtttatt gtgagcgaac ctcacttacc ccttgcaaag tcttggggtc attagaccaa
     9421 aaggaggaac atatcaatgg ctaaatacga aattctttat atcattcgtc caaacattga
     9481 agaagaagct aaaaacgctt tggtagcacg ttttgactct attttgactg acaacggtgc
     9541 aactgttgtt gaatcaaaaa cttgggaaaa acgtcgtctt gcatacgaaa tccaagattt
     9601 ccgtgaagga ctttaccaca tcgttaacgt tgaagcaaat gacgatgcag ctcttaaaga
     9661 gtttgaccgt ctttcaaaaa tcaacgctga cattcttcgt cacatgatcg tcaaaattga
     9721 cgcgtaagaa ggtaaactat gattaacaat gttgtacttg tagggcgtat gacacgtgac
     9781 gctgaattgc gttatacccc atcaaatgta gcagttgcga cttttactct tgcagtaaac
     9841 cgtacattta agagtcaaaa tggtgaacgt gaggctgatt ttatcaatgt cgttatgtgg
     9901 cgccaacagg ctgaaaatct tgctaactgg gctaaaaaag gctcacttat cggggtgaca
     9961 ggtcgtatcc agactcgtag ttacgataac cagcaaggac aacgtgtcta cgtgacagag
    10021 gtcgtggctg agaatttcca aatgttggaa agccgtagtg tgcgtgaggg tcacacaggt
    10081 ggagcttact ctgcaccaac tgcaaactat tcagcaccta caaattcagt accagacttt
    10141 tcacgtaatg aaaatccatt tggagcaaca aacccattgg atatttcaga tgatgattta
    10201 ccattctaat ggacaactaa acttataaag gagaaaaaac atggctcaac aacgtcgtgg
    10261 cggattcaaa cgccgtaaaa aagttgatta catcgcagca aacaaaattg aatatgttga
    10321 ttacaaagat actgagcttc ttagccgttt cgtttcagaa cgtgggaaaa tccttcctcg
    10381 tcgtgtaaca ggaacttcag ctaaaaacca acgtaaagta acaacagcta tcaaacgcgc
    10441 tcgcgtaatg gctttgatgc ctttcgtaaa cgaagattaa agaaaagacc cggttgggtc
    10501 tctttttcat gaacttgaaa acaagaaagc gaattaagac cccaacgggt cttttttcac
    10561 aagctttgaa atgagagagc gagttaggct cagtggctcc ctttttacga gtttgaaaac
    10621 aagagaacac attaaaagca cgatggagct ttttcataaa tatgtctttt ttttcatcca
    10681 agaaattaaa ataaaaatga taaacttttt gaaaataggg gatttgccta ctttatgata
    10741 taatggaaag agttagattg aaagaggtag tgagatggac gcgaaattaa gatacaaggc
    10801 aaagaagatc aagattgtct tttttgatat tgatgataca ttgcggaatt caaagacagg
    10861 gtttattcca actacaattc ccactgtttt taaacagttg cgtgaaaaag gaattttaac
    10921 aggaatcgcc tctggacgtg gcatttttgg tgttgttcca gagattcgtg atctcaaacc
    10981 tgactttttt gtaactttga atggggctta tatcgaagat aaaaaaggtc aggtcattta
    11041 tcagcatcag attgaaaagt catatgttga ggagtatatc tcttgggcta agcaagaagg
    11101 aattgagtat ggcttggttg ggagtcatga tgccaagttg tcgactcgca ccgatatgat
    11161 gagtgaagct atcaatccaa tttatcccga cttagatgta gatcccgatt tccatgaaaa
    11221 agaagatatc tatcagatgt ggacttttga agataaggga gatgacttgc acttgcctga
    11281 cagtctctca gacaaacttc gcatggttcg ttggcatcaa cattcgtctg atattgtgcc
    11341 gatttcaggc tccaaagcga cgggggtgga aaaggttgtg gaacaccttg gcttgaaacc
    11401 agagaaggtc atggtttttg gagatggtct caatgacttg gaactctttg attatgctgg
    11461 aatcagcgtt gccatgggaa tttctcatga taaaatcaaa gaaaaagcag attatattac
    11521 aaaaacatta gaagaagatg gcatttttga tgccttagaa gtatttggta tggtagaaaa
    11581 agaattgcat tttccacaag tagacattga aacagtagaa ggtcctcttg cgactattaa
    11641 gaccaatcac ggagacttac gtatcaagct tttccctgaa catgctccta aaacagtggc
    11701 taactttgta tctctttcaa aagatggcta ctatgatggt gtcattttcc accgtattat
    11761 caaggacttt atgatccaag gtggagaccc aactggaact ggtatgggtg gcgagtcaat
    11821 ctacggcgaa tcttttgagg atgaattctc agaagagctt tacaatatcc gtggtgctct
    11881 ttccatggca aatgctggtc caaataccaa cggcagccag ttctttatcg tgcaaaacca
    11941 acacctacct tattctaaga aagaaattac tcgtggtggt tggccagaac cgattgcaga
    12001 aatctatgcc aatcaaggtg ggacacctca cctagaccgc cgtcacacgg tttttggtca
    12061 gttagctgat gaagcatctt acgctgtctt ggatgtcatt gctgctgttg agacaggagc
    12121 tatggacaag ccagttgaag atgttgtaat tgaaactatt gaaatcgagg actaagatga
    12181 aaatcggtga taagctaaag gggcgtatta cagggattca gccctacggt gcctttgttg
    12241 agttagagac gggtgatacg gggctgattc acatttcaga aattcggaca ggatttattg
    12301 aaaatattca tgaaaccttg aaagtcgatg aagaggttca agttcaggta gtggatttag
    12361 atgaatttac ggggaaagcc agtctttcta tccgcacttt ggaggaagaa aagtaccagt
    12421 ttcctagacg gagacgcttt tcaagcgacc gctttaacta cggttttgct ccctttcgac
    12481 gaatgctacc aatctggact ggagaagccc tgcaccattt aaaaaagaag aagtagttta
    12541 gagttttata ttttttgtaa tgttaatata aatttgctat aataggacca tggaagaaga
    12601 acaattatta aaatcaggag agcgcattaa ccagctcttt tcgacagata tcaaaatcat
    12661 tcaaaataga gaggttttta gctattcggt ggatagtgtt ctcttatcac gatttccacg
    12721 ttttcctaag aaggggttga ttgtggattt ctgtgctggg aatggagcag tggggctttt
    12781 tgctagcact cgtactcaag cacagatatt gtctgttgag attcaggagc gtttggcgga
    12841 tatggctgaa cgctctgtcc gtttgaatgg attagaggag caaatgcagg tcatctgcga
    12901 tgatttgaaa aatatgcctg ctcacattca ggggagtaag gtggatatga ttttgtgtaa
    12961 tccaccctat ttcaaggtgg atccttattc taatctgaac gagagtgaac attatctctt
    13021 ggctcgacac gaaatcacga ctaatttgga agaaatctgt catagtgccc agagtattct
    13081 caagtctaat gggcgtttgg ccatggttca tcgtcctgat cgacttctgg atattttgga
    13141 tacgttaaaa cgacataatc tagcccctaa gcgcctgcag tttgtttatc caaaaagaga
    13201 aaaggaagcc aatatgcttt tgattgaggc gatcaaggat ggctcaacaa gtggctttaa
    13261 ggtcttacct cctttgattg tccacaatga tgatggctct tatacgcccg aaatcgaaga
    13321 gatttattat ggatcataag gcttatatgt acgttctgga gtgtcgtgat ggatcctact
    13381 atataggcta tacgactgat atgagaagac gcctcgctat ccacaatagt gggaagggag
    13441 ccaaatatac acgagcacgc ttgccagtca aacttatcta tgctcaaggt tttgccagta
    13501 aggaagaagc catgtcggct gaagctcttt tcaagcgtaa gaagaggcca cagaaggaag
    13561 aatttttatc tgaaaatcaa gatagaaatt tactcagtta ttttgaagaa tcgtggggag
    13621 tcctttgact cctcttacct ttgtcaaaaa gcgaaaaaaa tgctacaata aagaaaataa
    13681 acaaaatgag gtattatcat gtccaagatt ctagtatttg gtcaccaaaa tccagactca
    13741 gatgccatcg ggtcatctgt agcttttgcc taccttgcaa aagaagctta cggtttggat
    13801 acggaagctg ttgcccttgg aactccaaat gaagaaacag cctttgtctt gaactatttt
    13861 ggtgtggaag caccacgtgt tatcacttct gccaaagcag agggggcaga gcaagttatc
    13921 ttgactgacc acaatgaatt ccaacaatct gtatcagata tcgctgaagt agaagtttac
    13981 ggtgttgtag accaccaccg tgtggctaac tttgaaactg caagcccact ttacatgcgt
    14041 ttggagccag ttggatcagc gtcttcaatc gtttaccgta tgttcaaaga acatggtgta
    14101 gctgtgccta aagagattgc aggtttgatg ctttcaggtt tgatttcaga tacccttctt
    14161 ttgaaatcac caacaacaca cccaacagat aaaatcattg ctcctgaatt ggctgaattg
    14221 gctggtgtaa acttggaaga atatggtttg gcaatgttga aagctggtac caacttggct
    14281 agcaaatctg ctgaagaatt gattgacatc gatgctaaga cttttgaact caacggaaat
    14341 aatgtccgtg ttgcccaagt gaacacagtt gacatcgctg aagttttgga acgccaagca
    14401 gaaattgaag ctgcaatgca agctgccaac gaatcaaacg gctactctga ctttgtcttg
    14461 atgattacag atatcgtcaa ctcaaactca gaaatattgg ctcttggtgc caatatggac
    14521 aaggtcgaag cggctttcaa tttcaaactt gaaaacaatc atgccttcct tgctggtgcc
    14581 gtttcacgta agaaacaagt ggtacctcaa ttaactgaaa gctttaatgc gtaagatttt
    14641 gggtgtcagc tcaaaatcgg aaagtctagt ttgccttata tcgaaaggag tttcggctcc
    14701 tttttttcta ggagtgaagt atgttagaaa atggcgattt gatttttgtg agagatgggt
    14761 cagacatggg acaggccatc cagacttcca caggtaacta tagccatgtt gccatttatt
    14821 tggatgggat gatttatcat gctagtggac aggctggtgc tgtctgtcaa gaaccggcag
    14881 acttctttga gtccaatcat ttgtacgacc tctatgttta cccagaaatg gatatccagt
    14941 cggtgaagga aagagcttgc agacatcttg gagcacccta caatgcttct ttctatccag
    15001 atgcagctgg tttctactgc tcccagtata tagcagaaat cctacctatt tttgaaacta
    15061 ttcctatgaa atttggagat ggggaacagg agattagtga tttttggagg gagtattaca
    15121 tagaactagg tctgcctgtt cctctgaacc aagctgggac caatcctagt cagttggcag
    15181 catcgcctct gttacaatgt aaagaaagga atcttcatga ttcagatttt taattcatct
    15241 cgtttgacga gacagccatt tttggagaat tgatccgcta tctggaccag tatgaggatg
    15301 tgattctacg ggaaattaag gctcaatttc cagatgttgc agttgataaa ctcatggaag
    15361 agtatataaa ggcaagcttg attctacgtg aaaataagcg ctattacctc aattttccta
    15421 cgcttgaatc acttgatagt cttgaactgg atcaagagat ttttgtcaga gaagctagtc
    15481 cggtctatca agccttgttg gagcagagtt ttgagacgga attgcgcaat caaatcaatg
    15541 cagctatttt agttgaaaga cggactttgc gcgcattaaa atgaccctgt ccaattattt
    15601 ttacaaggtc aaacagcagt atcctttgac agaaaaacag caggagctct atgacatttt
    15661 aggagatgtt aatcctgagt atgcactcaa gtatatgacg gcttttttgt tgaaatttct
    15721 caaaaaagac cagcttatgc agaaatgccg tgatatcttt gtggacagtt tggttgtctt
    15781 aggctatatt gtgcaaaatg aagatagaaa gtatgagttg gctatcgatt ttgataagga
    15841 gagattaact ttctacttag cgtgatttct tgtttctgag cacattgttt gactttcctt
    15901 agtattcggt ataaactata tgtaaccggt aacacatatc ggaataaact aaaggagaca
    15961 atcatatgtc acttgaaaac aaattggaac aagcaacagg cgctgtcaaa gaaggttttg
    16021 gtaaagttac tggagacagc aagacagaac ttgaaggagc tgttgaaaaa acagttgcta
    16081 aggcaaaaga cgttgtagaa gacgcaaaag gtgctgtaga aggtgccgtt gaaggtttga
    16141 aaaacgtttt tactaaataa taggaaaaaa tcaagggttt cattttccct tgattttttc
    16201 tattcttata aataattttc tgcgacggct gtatctcctg ggtaggattc tttcttgccc
    16261 tggatgattt ggtaacaatc ggctccctta cccgcaataa taactgcatc taattcgtga
    16321 tttgtgatag ccattgccgc cttgatggct tcttggcgat ccgcaatctt ttcaacagga
    16381 tgattgatgt agctactaat ttcatctgca atggccattg ggtcttcata gttagggtca
    16441 tcagcagtca gaaagacttg aatctcaggg tgttgattga ggaggaggcc aaagtcctta
    16501 cgacgacttt ctcccttgtt tcctgttgat cccagaacca gagcaatctt tccggtttga
    16561 tgagtttcaa ccacattgat gagttttttc agactatccc cattgtgggc atagtcgatg
    16621 aagaccttgg ctccattttt ctgagtgagg acttccatac gaccaggaac gcgggttgca
    16681 gcgatgcctt ttttgatgtc ctcaagactt gctccgagac ggagacaagc aagtccagca
    16741 gcaactgcat tttcttggtt gaagttgcca atgagttgga tatcataatc tccagcgagt
    16801 ttacccgtag ctgaaaagct aaaggctttg gaattctcga tttggttatc aaattggcta
    16861 ccatagaaat catggtcttg atcttcaacc tgttctttca agactgagaa gtggtccatg
    16921 tcactgttaa tgatgactgc tcggctattt tccatcaaga gacgcttgtg gtagaaatag
    16981 tcttcaaagc tagggtgttc aatcgggccg atatggtcag gagtgatgtt aagaaagact
    17041 cctacatcaa aggtcagtcc atagactcga tggactagat aggcttgact ggagacttcc
    17101 atgatgaggt gggtacggtc attttgcaca gcctgattca tcatgtcaaa gaggtcaata
    17161 ctctcagggg ttgtcaacgc tgacttaaag aaagtctcgc catcaagagt tgtgttcatg
    17221 gtcgacaaca tagcaggtct atgcccttga gataagatgt tataggcgaa ataggttgct
    17281 gttgtcttac ccttagtacc agtaaaggca aggagtttga gtttctcttg tggattacca
    17341 tagaactcca tggcaatcaa actcatggct ttctttatat cgttcacaat gatgacaggg
    17401 atatcgactt cgtagtcctt ttcagctaca taccaagcta aaccttgtgt tatagcagaa
    17461 agaaggtatt cttttttaaa ggcagcgcct tttgcaaaaa aaagagtgtc ttctgttact
    17521 tttcggctgt cgtagctgat gctatcaaaa ataactttgc tgtagttgta gtggtaatga
    17581 ccttggtcaa taatttcgcg aaaaaggcca tctttcttta aaatatctaa tacggtttca
    17641 atcttaatca tactttctat tgtaaaccga aagtcgtaaa tttacaagta acaaggaaaa
    17701 gtttataatg gaagataagg agtttttcct agttatcaaa attgaatgag gaatctatgt
    17761 cgcacgaaaa caatcaccag caggcccaga tgttacgggg gactgcttgg ctaacggcta
    17821 gtaactttat cagtcgccta ctcggggctg tttacattat cccttggtac atctggatgg
    17881 gggcttatgc agctaaggca aatggtctct ttaccatggg ttacaatatc tatgcttggt
    17941 tcttgttggt ttcaacagcg gggattccag ttgcggtggc caagcaagtt gccaagtata
    18001 ataccatgcg agaagaagag catagctttg ccctgattcg gagcttctta ggctttatga
    18061 caggactagg cctggttttt gctttagtct tgtatgtctt tgctccttgg ctagcagact
    18121 tgtctggcgt gggcaaagac ttgatcccaa tcatgcaaag cttggcttgg ggagtcttga
    18181 ttttcccgtc tatgagtgtt atccgaggat ttttccaagg gatgaataac ctcaaaccct
    18241 atgccatgag ccaaattgct gagcaggtca ttcgtgttat ctggatgctc ctagcaacct
    18301 ttatcattat gaagctcggt tcaggagatt atctagcagc cgttacccaa tcaacctttg
    18361 ctgcctttgt cggtatggta gccagttttg cagtcttgat ttatttcctt gcccaagaag
    18421 gttcactcaa aagagtcttt gaaacaggag ataagattaa cagtaagcgt ctcttggttg
    18481 ataccattaa ggaagccatt ccttttatcc tgacagggtc tgccatccag ctcttccaga
    18541 ttttggatca gctgaccttt atcaatagta tgagctggtt taccaactac agcaatgagg
    18601 acttggttgt catgttttct tatttctcag ccaatcctaa taaaatcacg atgattttga
    18661 tttctgtagg ggtttcgatt gggagtgttg gtttgccact tttgacggaa aactatgtca
    18721 agggggactt gaaagcagct tctcgtctcg ttcaggacag tctcacccta ctctttatgt
    18781 tcttgctacc agcaacggtt ggagtggtta tggtaggaga acctctttat acggtcttct
    18841 atggtaagcc agatagtttg gctctgggct tatttgtctt tgcagttttg cagtctatta
    18901 ttttaggctt gtacatggtc ttgtctccaa tgcttcaggc catgttccgc aaccgcaagg
    18961 ccgttctcta ttttatctat ggttctattg ccaagctagt cttgcaacta cctaccatcg
    19021 ccctcttcca cagttatggt cctttgattt caacaaccat tgctctcatc attcctaacg
    19081 tcttgatgta tcgggatatt tgtaaagtaa ctggtgtcaa gcgcaaggtg attttgaagc
    19141 gaaccatttt aatcagtttg ctgaccctag tcatgtttct gttaatagga accatccagt
    19201 ggctgttagg atttttcttc caaccaagtg gacgtttgtg gagcttcttt tatgtagctc
    19261 ttgtcggtgc catggggggt ggactttata tggttatgag tctgcgtacc tatttattag
    19321 ataaggtaat aggaaaagcc caagcagatc gcctgcgagc aaaatttaag ctttcgtaag
    19381 gtagcattta taaataaaag gaataagttg aacaatcttt taggagaact tgaagcttat
    19441 tcctttttta gcgtaaaaat agctaaaatt atatttcaaa aatagaaaat gaggcttttt
    19501 tcgatttttt ggaaaaaatc attgactaaa caaactaaac gttgtataat aaaacaaata
    19561 tttaaagcag gaggttccgg aaatgaaaaa gtctaagagc aaatatctaa ccttggcagg
    19621 tcttgtcctg ggtacaggag ttttattgag cgcgtgtgga aattctagca cggcgtcaaa
    19681 aacatacaac tatgtttatt caagtgatcc atctagcttg aactatctag cagaaaaccg
    19741 cgcagcaaca tccgatattg ttgcaaattt ggtagacggg ttattagaaa atgaccaata
    19801 tgggaatatt attccatcat tagcagagga ttggactgtt tctcaggacg gtttgaccta
    19861 tacctacaaa cttcgtaagg atgccaagtg gtttacttct gagggagaag aatatgcgcc
    19921 tgtaactgcc caggattttg tgacaggttt gcaatatgca gctgataaaa aatcagaagc
    19981 cttgtatcta gtgcaggact ctgttgctgg tttggatgac tatatcactg gtaaaacaag
    20041 cgacttttca actgtcggtg tcaaggcact tgatgaccaa acggttcaat atactttggt
    20101 taaaccagaa ctttactgga attcaaaaac acttgcaacg atactttttc ctgttaatgc
    20161 agatttcctg aaatcaaaag gggatgattt tgggaaggcg gatccatcta gtattttgta
    20221 caatggacct ttcttgatga aagcacttgt ctcaaaatct gctattgaat ataagaaaaa
    20281 ccctaattac tgggatgcta agaatgtctt tgtagacgat gtgaaattga cctactatga
    20341 tggtagcgac caagaatcac tggaacgtaa ttttacagct ggtgcttata ctacggctcg
    20401 tctttttcct aacagctcca gctatgaagg gattaaagaa aaatacaaaa acaatatcat
    20461 ctatagtatg caaaattcaa cttcatattt ctttaatttt aacctagata ggaagtctta
    20521 caattatact tctaaaacaa gtgacattga aaagaaatcg actcaggaag cagttctcaa
    20581 taaaaacttc cgtcaggcta tcaattttgc ttttgacaga acatcttatg gggctcagtc
    20641 tgaagggaaa gaaggtgcaa caaagatttt gcgtaaccta gtggttcctc caaactttgt
    20701 cagtatcaag ggaaaagact ttggtgaagt tgtagcctct aagatggtca actatggtaa
    20761 ggaatggcaa ggtatcaact ttgcggatgg tcaagaccct tactacaatc ctgagaaagc
    20821 caaggctaag tttgcggaag ctaagaaaga actcgaagca aagggtgttc aattcccaat
    20881 ccacttggat aagactgtgg aagtaacaga taaagtaggc atacaaggag ttagttctat
    20941 caaacaatca attgaatctg ttttaggttc tgataatgta gtgattgaca ttcagcaatt
    21001 aacatcagat gagtttgaca gttcaggcta ctttgctcaa acagctgctc agaaagacta
    21061 tgatttatat catggcggtt ggggacctga ttatcaagac ccgtcaacct atctcgatat
    21121 ttttaatact aatagtggag gatttctgca aaatcttgga ctagagcctg gtgaggccaa
    21181 tgacaaggct aaggcagttg gactggatgt ctatactcaa atgttggaag aagctaataa
    21241 agagcaagat ccagccaaac gttatgagaa atatgctgat attcaagctt ggttgattga
    21301 tagttcttta gttcttccaa gtgtttcgcg tgggggaaca ccatcattga gaagaaccgt
    21361 accatttgct actgcctatg gtttaaccgg tacaaaaggg gttgaatcat ataaatacct
    21421 caaagtacaa gataagattg tcacaacaga cgaatatgca aaagccagag aaaaatggtt
    21481 gaaagaaaaa gaagaatcca ataaaaaagc ccaagaagaa ttggcaaaac atgtcaaata
    21541 aaatctaatt gtagataagt ttgtgtaaga agtctttgtg cttaaaaacg cataatatca
    21601 ggtatataaa atcctagatg ttatgcgttt tgttatagga agatttatta gattttatcc
    21661 tcaaattgag ttattcccga ctttatccgt tgaaatatta taaggagtat ttatgaaatt
    21721 aaaattatta agagtagata ctaaggtgat tatggggagt ttcttacttg ttctgtctag
    21781 tctacttgct ttgttgcttc cccttatctt aaagggttta atagatggga gttctattga
    21841 aaatataggt tccaaagtat ttcaatcgtt tttgattttt attggtcaag ccttgttttc
    21901 ttctattggt tactatctgt ttagtcaatc gggtgaaaaa aagatagcaa aaatcaggaa
    21961 aaaagtgata gaggggttga tttatgcaga gaaatccttc tttgataaga gccaaagtgg
    22021 ggagttgact tctgccattg tcaatgacac gagtgtcatt cgtgagtttt taattacgac
    22081 tttcccaaat attattctga gtttagttat ggtacttggt tccattgtag tcttatttag
    22141 tcttgattgg aatctttctc tacttttatt catcactctt ccttgtatga tgtttattat
    22201 cttgctcctt tccaatatca gtgaaaagta tagtcgtcgt ttacaggagg aaatcggatt
    22261 tttaacaggg caattgactg aaaagattca agaacatgaa ttaattaaga ctaaccaagc
    22321 agagaaaagt gtacaggatg ttttggataa ttgtattgaa agggtacaaa acaattcact
    22381 gaaatcagat agggttactt cttttgagac cccgtttgct ctcttattta tctttgcgac
    22441 tatagctgtg atgctaacct atgggggtta tcgggtcagc gcaggatata tatctgtggg
    22501 aaccttggtt tcgtttttga tttacctctt tcaattactt aatcctatta gtaatatagc
    22561 taattttgta actgtttatt ctaggagcaa gggatcttca gttgcactgg agaacttgct
    22621 tgcagttcct aaagaaaaat ttgagtgagg aaaatcggta tcaggacaag ggttgaattt
    22681 taaccatgtc tattttggtt atgatgaaaa tcgacctgtc ttaaaggata ttacttgttc
    22741 aattttcaag gggcaaaaaa ttgcttttgt tggaccatct ggatcaggaa aatcaacgat
    22801 tgtgcgtttg ttagagcggt tttataaacc gctttcagga gatattctaa tggagcaatc
    22861 aagtatatat gattttaact taaaagaatg gagaagtaaa atcgcttagt aactgatgat
    22921 gaattgatga aagtgctaga cttagtatca ctaggtgatg agattcgctc catgaaagag
    22981 ggactagata ctgaagttgg tgaacgcgga cgactcttgt caggggggca aagccaaaga
    23041 cttcaaatag ctagagccta cttaaaagat gctgaaattc ttatatttga tgaagccact
    23101 gctaatcttg atgcggattc tgagtatgcg attatcagta gcctctattc tgtattaaag
    23161 gagaagacgg ttgtgattat agcgcatcgt ttgtcaacgg taaaagatgt ggattgtatt
    23221 ttcttcttag aggaggggaa aatcactggc tcaggaactc ataaggaact actggaaaat
    23281 catgagcgtt atgctcgttt tgtgcaggag caaatgatag agtgaaggtg tcttttgaga
    23341 ttcaccattt tatagtctat taaagggagc aggaaaaact ccctttttat atagtttgaa
    23401 actataacta gctcttgaaa agaagaaaat gagttgatga aaataagtgg tacaatagtt
    23461 actatagatt tggaggtatt gtatgagcaa ggaattacac attaacacaa ttttggccca
    23521 ggcgggtatt aagtcagatg aagcgacagg tgcattggtg acaccgcttc atttttcaac
    23581 gacctatcag catccagagt ttggtcgatc tactgggttt gactatacgc gcactaaaaa
    23641 tccaactcgt agtaaggctg aggaagtctt ggcggctatt gagtcagcag actatgccct
    23701 agcgactagc tcagggatgt cagctattgt actggccttt agcgtctttc cagtaggaag
    23761 taaggtcttg gcagtgcgtg atctttacgg tggttctttt cgctggttta accaagtgga
    23821 gcaggaaggt cgtttccatt ttacctatgc caatacagaa gaagagttga ttgccgagtt
    23881 agaaaaggat gtggatgttc tctatatcga aaccccaacc aatcccttga tgttggaatt
    23941 tgatatcgaa aaactagcaa aattggctca tgctaagggt gccaaagtgg tggtggacaa
    24001 taccttctat agccctatct accaacgtcc gattgaagat ggagcagata tcgttctcca
    24061 ttcagcaacc aagtatctag caggccacaa tgatgtcttg gctggagtgg ttgtgaccaa
    24121 tagtttagaa ctatacgaga agctttttta caatctcaat acaacagggg cagtcttgtc
    24181 tccatttgac agctaccagt tgcttcgtgg tctcaagacc ttatctcttc gtatggagcg
    24241 ctcaacagct aacgcccaag aagtggttgc ctttttgaag gattctccag cagttaagga
    24301 agttctctac actggtcgtg gaggcatgat ttcctttaaa gtagccgatg aaacacgcat
    24361 tcctcatatt ttgaacagtc tcaaggtctt ctcttttgcg gaaagtttgg gcggagtgga
    24421 aagtcttatt acttatccaa cgactcaaac tcatgctgat attccagcag aagtacgcca
    24481 ttcttatggt ttgacagatg acctcttgcg tttgtctatt gggattgagg atgctagaga
    24541 tttgattgca gatttgcgcc aagccttaga aggataagac aaagatggga aaatatgatt
    24601 ttacaagcct gcccaaccgt ttagggcacc atacctataa atggaaagaa acagaaacgg
    24661 atagtgaagt tctaccagct tggatagcgg atatggactt tgtggtcttg cctgaaatcc
    24721 gccaagccgt gcaaacttac gcagaccaac tggtttatgg ttatacctat gccagtgaag
    24781 acttaattaa ggaaattcaa aagtgggaag ctacacaata cggttacaac tttgacaaag
    24841 aggctcttgt ctttatcgag ggtgtggtac cagccatctc aacagctatt caaaccttta
    24901 caaaagaagg cgaggcggtt ttaattaaca cgcctgtcta cccacccttt gctcgcagtg
    24961 tcaagttgaa taatcgtaga ttgattacta attccttagt ggaaaaggat ggtctgtttg
    25021 agattgactt tgaccaactt gaaaaggatt tggtggaaga ggaggttaaa ctctatattc
    25081 tttgcaaccc tcacaatcct ggtggacgtg tttgggaaaa agaagtgttg gagaagattg
    25141 gccaactttg ccaaaaacac ggtgttttgt tagtttcgga tgagattcac caagatttga
    25201 ccctctttgg tcacaaacac cagtctttca ataccatcaa tcctgccttc aaaaattttg
    25261 ctatcgtctt gagcagtgcc actaaaacat ttaatattgc tggaacaaaa aattcctatg
    25321 cagtcattga aaatcctaag ttgagactgg ctttccagaa acgcctgttg gccaataatc
    25381 agcatgaaat ttcaggcttg ggttatttgg cgacagaagc tgcctatcga tacggtaaag
    25441 attggctaga ggaactcaag caagtctttg aagaccacat caattatgtg gtggatctat
    25501 ttggaaaaga gactaaaatc aaggtcatga aaccgcaagg tacctacttg atttggcttg
    25561 acttttcagc ctatgacctg actgatgaaa cattgcaaga gttgttgaga aatgaagcca
    25621 aggttatcct caaccgtggt ttggattttg gagaggaagg aagtctccat gcccgcatca
    25681 atatagctat gcccaaatct ctgttgcaag aagtctgtca gcggattgtg gctacttttg
    25741 ccaaacgtta aaaatccagc cttctaggag aaaagtcttc ctagaaggct attttcatag
    25801 gcgaaaatat ggtataataa aaagataagg taaaggtgaa aatatggcta aattgattcc
    25861 ggggaaaatt cgtatcgaag gtgttgccct ttatgaaact ggtaaggttg atatcatcaa
    25921 ggaaaagaac aatcggctct acgctcgcgt tgcagaagaa gaactgcgct atagtttaga
    25981 ggatgatttg gttttttgtg cctgtgattc ttttcaaaag aggggctact gtgtgcattt
    26041 ggcagcgcta gagcattttc tgaaaaatga tgagcgtggt caggaaatct tgtggagtct
    26101 ggaagaaggt catgaagaaa aagaggccgt tgaaaccaag gtgaccttgg gtggcaagtt
    26161 tttgaatcga attttatctc caaaatcaga atgcgcctat gagttatcag ctgtgggtca
    26221 ggtggaagca ggaaccaatc atatcttgtg gactctgaga atcggccaaa tcaatagcca
    26281 aaaatactat gtcattcggg atattccact ttttttaagg attgtcgagc agagaaagtc
    26341 gtatatgatt ggcaagattt atgaggagtc tctttcttgg gaagcctttg atgatgccag
    26401 ccaagaactt ttgactttct tgcacggact aacggaggaa gggctggttc cagacctctt
    26461 tttccaaaac caaggtcggc acctcttttt ccctctgacc ttttttgagc agggtgtgaa
    26521 tttactgatg gccttgcccc attttcaatt tgaccatcaa gtggatagct accaaaccct
    26581 gctttttcag gatatgcatg ctgatgccaa tctatttgcc tttacagtaa cagaatactc
    26641 ggactatttt gaaatggaaa tcagtgagag tcctagggtc aatgtctttt atcagggagc
    26701 agtacttttc cataaaggtc aggtttattt tttaacagac cagcagatgc gtcttctcaa
    26761 ggaaattaaa gcgttacctg tgggtcaaca aggaaagaaa tacctgcaat ttgatagcag
    26821 tgatcgagac aaattggcct cctgtctgac tctttttatc cagatgggca ccgtttcagc
    26881 tccagaacgt ctacaaatca aaacttttgc gccctctttt tactttgaca gggaagaaga
    26941 taatcggatt cgtttagaaa ttcagtttga ttatggaaat agacaggtat ctagccgaca
    27001 agagctagaa gaattaccat tttcaagtga cgcggactta gaagaaagaa ttttccaagt
    27061 ctgtttggct gcgggctttg aagccgattt tcaatcttgg cgtcaggcct taaaagcgga
    27121 gtctgtctat catttttttc atgatatcat tccagtcttt gaaaaactcg ggcatgttga
    27181 cctatcagat aaactagaag agctttatag cctagcgagt cctcaggtgc agattgcctc
    27241 caagggaggt ctcttggaaa tccagtttga ttttcaaaat attgcccagg aggaaatcga
    27301 ccaagccatg caggccttgg ttgccaatca ggatttttat attgattcgt ctaatcaagt
    27361 ttactttttc gatgaagaaa ccaagaaaat tcgccaaaat ctacaggaac tggggcaatt
    27421 tgaattaaaa gatgggacct tgcaggctcg gaaatccttg gcctacagtt tagctcatct
    27481 ctttgaaggg cgagaccgtg tttctttttc acaagaattc cagaatctgg cccaggattt
    27541 gacgcatcca gaggactttc ctttgcaagc aactcaggtc aaggctgact tgcgagatta
    27601 tcaggaaaag ggaattggct ggttgcagat gctccatcat tatggttttg gtgggatttt
    27661 ggctgatgat atgggacttg ggaaaaccct tcagaccatt gcttttttga ctagtcaagt
    27721 gacaaaagaa agtcgagtct tgattctcgc tccgtcgggt ttgatttaca actgggcgga
    27781 tgagtttcag aaatttgccc cacagttgga tgtggctgtt gttcatggtt tgaaagcaag
    27841 tcgtgaggag attcttgccg agagccatca aatctatgtg actagctatg ccaccttccg
    27901 tcaggacagt gagttttatc aggggatggc ctttgacttc cttttcttag atgaggctca
    27961 ggtcatgaaa aatgcccaga ccaagattgc ccagaccttg agacaatttg tggtgccgtc
    28021 ggtctttgcc ttgtcaggaa ctccgattga aaaccatctg ggtgagttgt ggtctatttt
    28081 ccaaatcgtc atgcccggac ttttgccaag caagaaagaa tttatgaaat tgccagcaga
    28141 gcgagtggct cagtttatca agcctttcgt gatgcgacgc aagaaagaag aagttctgac
    28201 tgaattgcca gacttgattg aggtggttta taaaaatgaa ctggaagacc agcaaaaggc
    28261 tatttacctt gcccagttac aacagatgcg agaccatctg gctcaagtgt cagaacagga
    28321 atttcagcga agtcgtgtgg aaattttatc tggtttgatg cgcttgcgtc aaatatgtga
    28381 cactcctgcc ctgtttatgg aagattatca gggagccagc ggcaaactag atagtctccg
    28441 agacctactg gtacaggtgg cagacggcgg acaccgtgtc ttgattttct ctcagttcaa
    28501 gggaatgttg gaaaaaattg aacaagaact gccagacttg ggcctgactt cctttaaaat
    28561 tacgggttca accccagcca aggaaagaca agacatgacc aaggccttta atcaaggaga
    28621 aagagatgcc tttctgattt ccctcaaggc tggtggggtc ggtctgaacc tgacaggtgc
    28681 agatacagtg atcttggttg acctttggtg gaatcctgcg gtggaagcgc aagccattgg
    28741 ccgtgcccat cggatgggtc aggaagaaac ggttgaggtc tatcgcttgg tgaccaaggg
    28801 aaccattgaa gaaaaaattc aggaactcca agaacaaaag aaacatctgg tgtcacaagt
    28861 attggacggc acagagtcac gtggtagtct gaccctagca gaaattagag aaattttggg
    28921 aatttctgaa gccagcactt gaaaaatcaa gacaatacgc tataatgaag tgttgaaagg
    28981 aaatagaaaa tgaaacaaga acgatttcca ttggtgtcag atgacgaggt catgttgact
    29041 gaaatgccag tcatgaatct ctatgatgag tctgatctga tcagtaatat caagggtgag
    29101 tatcgagata aaaattattt agaatgggct cctattgctg aagaaaaacc agtaaaaccg
    29161 attgaaaagc aagtagggaa acctaaaaaa gctcctttag gggttaaaaa agaaggaaag
    29221 agctatgcgg aggtggcgcg tgaagaagcg cgtgcagact tgaaaaagaa acgctctgct
    29281 aactatctaa ctcaggattt cagccttgcg agacgtcatt ctcagcccag tctagttaga
    29341 cagggcaatc aaccgacaac tcctttccaa aaggaaaatc ctggtgaatt tgtcaaatat
    29401 agccaaaaat tgacccagtc tcattatatc ttggcggaag aagttcattc tatccctacc
    29461 aagaatgaag aagtgtcagc acctgctcca aagaaaaaca attatgattt tctaaagaag
    29521 agccaaatct acaataaaaa aagtaaacaa acagaacaag aacgtcgggt tgcccaagag
    29581 ttgaatctga ccagaatgac agaataggga gaaaacatgt caaagacata tcattttatc
    29641 ggaattaagg gatcagggat gagtgccttg gccttgatgt tgcaccagat ggggcacaag
    29701 gttcagggat cagatgttga aaagtactac tttacccaac gcggtcttga gcaggcagga
    29761 attaccattc ttccttttga tgaaaagaat ctagacggtg atatggaaat tatcgctgga
    29821 aatgcctttc gtccagataa caacgtcgaa attgcctatg cggaccaaaa tggtatcagc
    29881 tacaaacgtt accatgagtt tctaggtagc tttatgcgtg actttgttag catgggagta
    29941 gcaggagcac atggaaaaac ttcaacgaca ggtatgttgt ctcatgtctt gtctcacatt
    30001 acagatacca gcttcttgat tggagatggg acaggtcgtg gttcggccaa tgccaaatat
    30061 tttgtctttg aatctgacga atatgagcgt cacttcatgc cttaccaccc agaatactct
    30121 attatcacca acattgactt tgaccatcca gattatttca caagtctcga ggatgttttc
    30181 aatgccttta acgactatgc caaacaaatc accaagggtc tttttgtcta tggtgaagat
    30241 gctgaattgc gtaagattac gtctgatgca ccaatttatt attatggttt tgaagctgaa
    30301 ggcaatgact ttgtagctag tgatcttctt cgttcaacaa ctggttcaac cttcaccgtt
    30361 catttccgtg gacaaaactt ggggcaattc cacattccaa cctttggtcg tcacaatatc
    30421 atgaatgcga cagccgttat tggtcttctt tacacagcag gatttgattt gaacttggtg
    30481 cgtgagcact tgaaaacatt ttccggtgtt aaacgtcgtt tcactgagaa aattgtcaat
    30541 gatacagtga ttatcgatga ctttgcccat catccaacag aaattattgc gaccttggat
    30601 gcggctcgtc agaaataccc aagcaaggaa attgtagcag tctttcaacc gcataccttt
    30661 acaagaacca ttgccttgtt ggacgacttt gcccatgctt taaaccaagc agatgctgtt
    30721 tatctagcgc aaatttatgg ctcggctcgt gaagtagatc atggtgacgt taaggtagaa
    30781 gacctagcca acaaaatcaa caaaaaacac caagtgatta ctgttgaaaa tgtttctccg
    30841 ctcctagacc atgacaatgc tgtttacgtc tttatgggag caggagacat ccaaacctat
    30901 gaatactcat ttgagcgtct cttgtctaac ttgacaagca atgttcaata ggatgttccc
    30961 atggaaattc caattaagat cattcaggca agcaagtctg atttgcctga gataggggca
    31021 cttcagacct cgtcttttcc agctgaaaag cagcaacttt cccatatttt agaagaaagt
    31081 atccgtaagt gtgcggatac ctttcttcta gctagggatg aaaatcaact tttaggctat
    31141 attttatcaa gtccccagtc agacaatccg caatatctaa aagtacattc tttagtcatc
    31201 gagtctgacc atcagagaca gggcttggga acacttcttc ttgcagcctt gaaagaggtg
    31261 gcagttgatc tggattacaa agggattcgt ttggagagtc ctgatgagct gctttcctat
    31321 tttgaaatga acggttttgt tgatgaagaa gcaactttgc tctatgcaac tagccagggc
    31381 tatagtatga tttggtttaa tcccttttat ctggaggaac aatgaaaatc agacaagcaa
    31441 gattagaaga tttggatcgg attgttgaac ttgaatttga aaatttttcg gtcgaagaag
    31501 ccattcctcc ttctgtcttt gaagcacatt tgagagaaat tcagacctct tttctggttg
    31561 ctgaaaaaga aggaagaatc atgggttata tcgaaggacc agttggcctg caccgccatc
    31621 tgcaagacca gtcttttaca gaagaaataa aagactatag tcatgagcct ggtggttata
    31681 tctctgtgac ctgtctgtct attgccaagg aggcacaggg actcggactg ggtcagaaat
    31741 tgctgacagc tttgaaagaa gttgctcttg aagatgagag agatggcatt aatctaacct
    31801 gtcatgacta tctcatcgcc tattatgaaa aacatggatt tgtcaacgaa ggccagtccc
    31861 agtcaacctt tgcaggggaa acatggtatg atatggtctg ggaaatgaaa aaataagtta
    31921 ggaaaagtat catagattgc tttttttgga cttttaagat ataatattat ggattatcaa
    31981 caaggaggaa aaacttttga gtgaaaagtc aagagaagaa gagaaattaa gctttaaaga
    32041 gcagattctg agagatttag aaaaagtaaa aggctatgat gaagttctga aagaagatga
    32101 ggcagtagtt cgcactcctg caaatgaacc ttcagctgaa gaactcatga ctgattcctt
    32161 gtcaacggta gaggagatta tgagaaaagc tcctaccgtg cctactcacc caagtcaagg
    32221 tgtaccagct tctccagcag atgagattca aagagaaact cctggtgttc caagtcatcc
    32281 aagtcaagat gtaccttctt ctccagcgga agaaagtgga tcaagaccag gtcctgttag
    32341 acctaagaaa cttgaaagag aatacaatga aaccccaaca agggtagctg tttcctatac
    32401 gacggcagag aaaaaagcag aacaagcagg tccagaaaca cctacgcctg ctacagaaac
    32461 agtggatatc atcagcgata catcacgtcg tagccgtaga gaaggagcaa aacccgttaa
    32521 tcctaagaaa gagaagaagt cacatgtgaa agcttttgtg atttcattcc ttgtattcct
    32581 tgccttgctc tcagcaggtg gttactttgg ttaccagtac gtgctagatt ctttgttacc
    32641 tatcgatgct aattctaaga aatatgtgac ggttggaatt ccagaaggtt caaacgttca
    32701 agaaatcggt acgacgcttg aaaaagctgg tttggtaaag catggtctga tttttagttt
    32761 ttatgccaag tataaaaatt ataccgactt gaaagcaggt tactacaatt tgcaaaagag
    32821 tatgagtaca gaagacttac tcaaagagtt gcaaaaaggt ggaacagatg aaccgcaaga
    32881 acctgtactt gcgactttga caattccaga aggttatacc ttggatcaga ttgctcaagc
    32941 tgtgggtcaa ttgcaaggtg acttcaaaga gtctttgaca gcggaggctt tcttggctaa
    33001 agttcaagat gagacgttta tcagtcaagc agtagcgaaa tatcctactt tactggaaag
    33061 tttgcctgta aaagacagcg gtgcgcgtta tcgtttggaa ggataccttt tcccagctac
    33121 atactctatc aaggaaagca caactattga gagcttgatt gatgagatgt tagctgctat
    33181 ggataagaac ctatctcctt actatagtac tatcaaatct aaaaatttga ctgtcaatga
    33241 gttgttgacc attgcttcct tggtcgaaaa agaaggtgcc aagacagaag atcgtaagct
    33301 cattgcaggt gtattctaca atcgtttaaa tcgtgatatg ccacttcaaa gtaatattgc
    33361 aatcttgtat gcccaaggaa aactggggca aaatatcagt ctagctgagg atgttgcgat
    33421 tgataccaac attgattcac cttataatgt ttataaaaat gtaggtctca tgcctggtcc
    33481 agtcgatagt ccaagtctgg atgcgattga gtcaagcatc aatcaaacta agagcgataa
    33541 cctctacttt gtagcagatg tcacagaagg caaggtctac tatgctaaca atcaagaaga
    33601 ccacgaccgc aatgtcgctg aacatgtcaa cagcaaatta aactaaacaa actaaaatta
    33661 tgtgatacgt cacataattt tctttagaaa atattatcag aagaaagttg agaaaaatgg
    33721 cagaaaaaac atatcctatg acccttgagg aaaaggaaaa acttgaaaaa gaattagaag
    33781 aattgaaatt ggttcgtcga ccagaagtgg tagaacgcat taagattgcc cgttcatacg
    33841 gtgacctttc agaaaacagt gagtacgaag cagctaagga tgaacaagcc tttgtcgaag
    33901 gacaaatctc tagcttagaa acaaaaatcc gctatgctga aatcgtcaat agcgacgcag
    33961 ttgcccagga cgaagtagcg attggtaaaa cagtcaccat ccaagaaatt ggtgaggacg
    34021 aagaagaagt ttatattatc gtaggttcag ctggtgcgga tgcctttgca ggtaaggttt
    34081 caaatgaaag cccaattggg caggccttga ttggcaagaa aacaggtgac acagcaacca
    34141 ttgaaacgcc tgttggtagc tatgatgtaa aaatcttgaa ggttgaaaaa acagcctaaa
    34201 aacagaaaaa ggagtgggga ggcgatgtgc ttcactcact cctttttcca ttttgctatt
    34261 cttcgaaaat ctcttcaaac cacgtcagcg tcgccttgcc gtatgtatgg ttactgactt
    34321 tgtcagtttc atctacaacc tcaaaac
//
LOCUS       DAVBIC010000021        33324 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.021, whole genome shotgun sequence.
ACCESSION   DAVBIC010000021 DAVBIC010000000
VERSION     DAVBIC010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33324)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33324)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33324
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.021"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            <1..327
                     /locus_tag="VQ664_000958"
     CDS             <1..327
                     /locus_tag="VQ664_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HET2789138.1"
                     /translation="KPQTEKPEEETPREEKPQSEKPESPKPTEEPEEESPEESEEPQV
                     ETEKVEEKMREAEDLLGKIQDPIIKSNAKETLTGLKNNLLFGTQDNNTIMAEAEKLLA
                     LLKESK"
     gene            749..979
                     /locus_tag="VQ664_000959"
     CDS             749..979
                     /locus_tag="VQ664_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HET2789139.1"
                     /translation="MESIGIGLVIVSHSKHIAEGVVELISKVAKDVPITYVGGTEGGG
                     IGTSFDQVDRVVSENPADTLLAFFDLGSAIKC"
     gene            1383..2096
                     /locus_tag="VQ664_000960"
     CDS             1383..2096
                     /locus_tag="VQ664_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HET2789140.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFAHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIERDYNLYAATNGITAIQTGRLAQSGLAPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            2154..2756
                     /locus_tag="VQ664_000961"
     CDS             2154..2756
                     /locus_tag="VQ664_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789141.1"
                     /translation="MSEVDFNEAVNYEFTSDTCQLANSIYQSLFKFFDKKNFSGDLIF
                     TWKSPSLVKEGDYIGRRDSQVDNLRVIGNIFPNYLTNRKYSLNMNRNGCMGDFPHDFF
                     DIYLDHVAKYAYEQKVNNIKEYYPLKRAILHQENALYFRFFSNFDDFLEKNYLKTIWQ
                     VSKETPFSEMDFNMFKNISEKIIFERGSKMLNDLKSNYKK"
     gene            2892..3545
                     /locus_tag="VQ664_000962"
     CDS             2892..3545
                     /locus_tag="VQ664_000962"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HET2789142.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGIIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR"
     gene            3555..4019
                     /locus_tag="VQ664_000963"
     CDS             3555..4019
                     /locus_tag="VQ664_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HET2789143.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAAREILEETGLKAKPVLKGVITFPEFTPDLDWYTYVFKVTEFEGDLIDCNEGT
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            4032..5300
                     /locus_tag="VQ664_000964"
     CDS             4032..5300
                     /locus_tag="VQ664_000964"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HET2789144.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETI
                     DATGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAVGFSDDGIPLESSKIV
                     KEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALLLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLG
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFEAGYLAENGPADITIFDAKADRLVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            5314..5574
                     /locus_tag="VQ664_000965"
     CDS             5314..5574
                     /locus_tag="VQ664_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789145.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            5585..6946
                     /gene="pdrM"
                     /locus_tag="VQ664_000966"
     CDS             5585..6946
                     /gene="pdrM"
                     /locus_tag="VQ664_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HET2789146.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPTILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDKIKEGVRLGLPIGGTVFAEVAIFSVVGLIMAKFSSLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTARFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKR"
     gene            7100..8068
                     /locus_tag="VQ664_000967"
     CDS             7100..8068
                     /locus_tag="VQ664_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HET2789147.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGPVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD"
     gene            8084..9076
                     /locus_tag="VQ664_000968"
     CDS             8084..9076
                     /locus_tag="VQ664_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HET2789148.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDKNPVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEGISVEIVDPRTLVPLDKDIIINSVKKTGKVVLVNDAHKTSGYISEIS
                     AIISESEAFDYLDAPIRRCAGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKE"
     gene            9294..10337
                     /locus_tag="VQ664_000969"
     CDS             9294..10337
                     /locus_tag="VQ664_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HET2789149.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGEIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     KVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            10401..12086
                     /gene="lpdA"
                     /locus_tag="VQ664_000970"
     CDS             10401..12086
                     /gene="lpdA"
                     /locus_tag="VQ664_000970"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HET2789150.1"
                     /translation="MPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKVSMELEA
                     EEDGYLIAILKGDGETVPVTEIIGYLGEERENIPTAGAASPEASPVPVASTSNDDGKS
                     DDAFDIVVIGGGPAGYVAAIKAAQLGGKVALVEKSELGGTCLNRGCIPTKTYLHNAEI
                     IENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVTVHKGIGT
                     ITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMQSPLVMTSDDILEMNEVPESLV
                     IIGGGVVGIELGQAFMTFGSKVTVIEMMDRIVPAMDAEVSKNLRLILERKGMTILTGT
                     KLQEIIEENGQLRIKVEGKDDIIASKALLSIGRMPDLEGIGEVEFELDRGCIKVNEYM
                     ETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAVAKLNLTPAAIYTLPEVA
                     AVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVIADKKYGEIIGVHIIGPA
                     AAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKKK"
     gene            12150..13139
                     /locus_tag="VQ664_000971"
     CDS             12150..13139
                     /locus_tag="VQ664_000971"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HET2789151.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAEINHIKDTKFGTWDWNYGKSPEFNVRRGTKFTSGKVEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEDVLRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(13206..14276)
                     /gene="xerS"
                     /locus_tag="VQ664_000972"
     CDS             complement(13206..14276)
                     /gene="xerS"
                     /locus_tag="VQ664_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HET2789152.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVNDEQKNALDSL"
     gene            complement(14860..16410)
                     /locus_tag="VQ664_000973"
     CDS             complement(14860..16410)
                     /locus_tag="VQ664_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HET2789153.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHLIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMPDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFIIIIPVGIFLPQIIGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGSLVGVICVNLGLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
     gene            complement(16426..17205)
                     /locus_tag="VQ664_000974"
     CDS             complement(16426..17205)
                     /locus_tag="VQ664_000974"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HET2789154.1"
                     /translation="MATIKEIKELLVTVKELESPIFLDLEKDNRSGVQKEISKHKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIAGIDEVGRGPLAGPVVAAAVILPKNCKIKG
                     LNDSKKIPKKKHLEIFQVVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFPGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKES"
     gene            complement(17192..18043)
                     /gene="ylqF"
                     /locus_tag="VQ664_000975"
     CDS             complement(17192..18043)
                     /gene="ylqF"
                     /locus_tag="VQ664_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HET2789155.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQGIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEAPVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EGLDGND"
     gene            complement(18250..18426)
                     /locus_tag="VQ664_000976"
     CDS             complement(18250..18426)
                     /locus_tag="VQ664_000976"
                     /inference="COORDINATES: protein motif:HMM:NF012948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HET2789156.1"
                     /translation="MQAGIPTDNEVSYALIYQQETLPATGSSTSALTALGLLAVGSLV
                     LLVHNMTGTVFCSL"
     gene            complement(18478..24369)
                     /gene="iga"
                     /locus_tag="VQ664_000977"
     CDS             complement(18478..24369)
                     /gene="iga"
                     /locus_tag="VQ664_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunoglobulin A1 protease"
                     /protein_id="HET2789157.1"
                     /translation="MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQE
                     TAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSK
                     NERQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGMGNGVLVSVHALENHLLL
                     NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDY
                     NVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQL
                     AEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYREETIETKIDFQEEI
                     QENPDLAEGTVRVKQEGKLGKKVEIVRIFSVNKEEVSREIVSTSTTAPSPRIVEKGTK
                     KTQVIKEQPETGVEHKDVQSGSIVEPAIQPELPEAVVSDKGEPEVQPTLPEAVVTDKG
                     ETEVQPESPDTVVSDKGEPEQVAPLPEYKGNIEQVKPETPVEKTKEQGPEKTEEVPVK
                     PTEETPVNPNEGTTEGTSIQEAENPVQPAEESTTNSEKVSPDTSSENTGEVSSNPSDS
                     TTSVGESNKPEHNDSKNENSEKTVEEVPVNPNEGTVEGTSNQETEKPVQPAEETQTNS
                     GKIANENTGEVSNKPSDSKPPVEESNQPEKNGTATKPENSGNTTSENGQTEPEKKLEL
                     RNVSDIELYSQTNGTYRQHVSLDGIPENTDTYFVKVKSSAFKDVYIPVASITEEKRNG
                     QSVYKITAKAEKLQQELENKYVDNFTFYLDKKAKEENTNFTSFSNLVKAINQNPSGTY
                     HLAASLNANEVELGPDERSYIKDTFTGRLIGEKDGKNYAIYNLKKPLFENLSGATVEK
                     LSLKNVAISGKNDIGSLANEATNGTKIKQVHVDGVLAGERGVGGLLAKADQSSIAESS
                     FKGRIVNTYETTDAYNIGGLVGHLTGKNASIAKSKATVTISSNTNRSDQTVGGLAGLV
                     DQDAHIQNSYAEGDINNVKHFGKVAGVAGYLWDRTSGEEKHAGELTNVLSDVNVTNGN
                     AITGYHYTGMKVANTFSSKANRVFNVTLEKDEVVSKESFEERGTMLDASQIVSKKAEI
                     NPLTLPTVEPLSTSGKKDSDFSKIAHYQANRALVYKNIEKLLPFYNKSTIVKYGNLVK
                     ENSLLYQKELLSAVMMKDDQVITDIVSNKQTANKLLLHYNDHSSEKFDLKYQTDFANL
                     AEYNLGNTGLLYTPNQFLYDRDSIVKEVLPELQKLDYQSDAIRKTLGISPEVKLTELY
                     LEDQFSKTKQNLGDSLKKLLSADAGLASDNSVTRGYLVDKIKNNKEALLLGLTYLERW
                     YNFNYGQVNVKDLVMYHPDFFGKGNTSPLDTLIELGKSGFNNLLAKNNVDTYGISLAS
                     QHGTTDLFSTLEHYRKVFLPNTSNNDWFKSETKAYIVEEKSTIEEVKTKQGLAGTKYS
                     IGVYDRITSATWKYRNMVLPLLTLPERSVFVISTMSSLGFGAYDRYRSSDHKAGKALN
                     DFVEENARETAKRQRDHYDYWYRILDEQSREKLYRTILLYDAYKFGDDTTSGKATAEA
                     KFDSSNPAMKNFFGPVGNKVVHNQHGAYATGDGVYYMSYRMLDKDGAITYTHEMTHDS
                     DQDIYLGGYGRRNGLGPEFFAKGLLQAPDQPSDATITINSILKHSKSDSTEGSRLQVL
                     DPTERFQNAADLQNYVHNMFDLIYMMEYLEGQSIVNKLSVYQKMAALRKIENKYVKDP
                     ADGNEVYATNVVKELTEAEARNLNSFESLIDHNILSAREYQSGDYERNGYYTIKLFAP
                     IYSALSSEKGTPGDLMGRRIAYELLAAKGFKDGMVPYISNQYEEDAKQQGQTINLYGK
                     ERGLVTDELVLKKVFDGKYKTWAEFKTAMYQERVDQFGNLKQVTFKDPTKPWPSYGTK
                     TINNVDELQALMDQAVLKDAEGPRWSNYDPEIDSAVHKLKRAIFKAYLDQTNDFRSSI
                     FENKK"
     gene            complement(24578..25756)
                     /locus_tag="VQ664_000978"
     CDS             complement(24578..25756)
                     /locus_tag="VQ664_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789158.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSLIFNGIGRSNC
                     VCRNAIKYAYELFNGVTGQRLFPIGSDCVRHFHRLPLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFAPERDYQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERAIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWILNSYFRELPEEKARFSRLLLEYRKSGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDHRSSAQGSWIEGILLNCLKPFLERLVI
                     "
     gene            complement(25926..29576)
                     /gene="addA"
                     /locus_tag="VQ664_000979"
     CDS             complement(25926..29576)
                     /gene="addA"
                     /locus_tag="VQ664_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HET2789159.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMAERILDQLARGVEISQLFISTFTVKAATELKERLEKKISKKIQET
                     DDVDLKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKETFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SESFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEICSLNQESDSQAYQAVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQ
                     FAKLGQLSDQITILDYQERYHQDTWKLAKTFQTFMSHFVEAYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQEGKLILLKENFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNKHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKVHENLYEKLVNAQKMAS
                     SQKGLIHTALVEKLKQFMDILASWRLYAKTHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAVELMTIH
                     KSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLESKEYPAAK
                     NGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIDEDQLTREAIGELETKSPLQ
                     DSSQADNRQSDTIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQIIDLSQQLTLASLTETLK
                     QVQTSQAVRDKINLDKILAFFDTALGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
     gene            complement(29573..32848)
                     /gene="rexB"
                     /locus_tag="VQ664_000980"
     CDS             complement(29573..32848)
                     /gene="rexB"
                     /locus_tag="VQ664_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HET2789160.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLECLSQQASFSITVTRFAQMARYLVLNDLPVKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMSFLDLENLTDEDKRADLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQITLVIDGFTRFSAEEERVVDLLHGKGVEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLL
                     RTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQTFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAENLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERQNLNQTTEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDQQGLENPAIPISPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLRPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGEQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLEKLDLADGKRLVGEKLKQAWLEKIREE
                     LNR"
     gene            complement(33048..33203)
                     /locus_tag="VQ664_000981"
                     /pseudo
     CDS             complement(33048..33203)
                     /locus_tag="VQ664_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
BASE COUNT         9515 a         6539 c         6861 g        10409 t
ORIGIN      
        1 aaacctcaga cagaaaaacc tgaggaagaa acccctcgag aagagaaacc gcaaagcgag
       61 aaaccagagt ctccaaaacc aacagaggaa ccagaagaag aatcaccaga ggaatcagaa
      121 gaacctcagg tcgagactga aaaggttgaa gaaaaaatga gagaggctga agatttactt
      181 ggaaaaatcc aggatccaat tatcaagtcc aatgccaaag agactctcac aggattaaaa
      241 aataatttac tatttggcac ccaggacaac aatactatta tggcagaagc tgaaaaacta
      301 ttggctttat taaaggagag taagtaaagg tagcagcatt ttctaactcc taaaaacagg
      361 ataggagaac gggaaaacga aaaatgagag cagaatgtga gttctagttc tcattttttt
      421 catgaaaatg tgcaaaatat agtagattga aactagaata gtatacctct acttctaaaa
      481 cattgttaga aatcgatttg actgtcctgt tcttatttca ttttactata tcttaacaga
      541 tagtgtaaat aaagataaac tatttactgg ctaattaatc agttaaacac tagttaagga
      601 gtaatgatga aaaaaagaac aatactatta ttgatggcca gtctgttagc tcttgtctta
      661 ggagcatgtg gtttcttgga catattgatc ctggatcatt ctcatcagga ttactcttta
      721 ctgctatttt agaaactggg gtggtttgat ggaaagtatt ggtattggtc ttgttatcgt
      781 ttcacattcc aaacacattg cagaaggtgt tgttgaactg attagtaaag tagctaaaga
      841 tgttccgatt acttatgtag gaggaaccga gggcggagga attggaacga gttttgatca
      901 agtagatagg gttgtttccg aaaatccagc agatacttta cttgcctttt ttgacctagg
      961 ttctgctata aaatgttaag taaatgattt caaaatcaga aagggattgc tttgggcagt
     1021 tcctttttaa tgtaaatgta aaaggagtag aatcatagtg tttctaaatt gtgaatcaat
     1081 caaaactgat tgtgatgggg ctattctagc tttagaatcc ttcaaaaatt aaaatttaag
     1141 gcaatcaatt acttggaaga gtatgaaagc atttagttta taggaattct aggcctagaa
     1201 ttacatatgt atttatgaag ataggggtgt tcgatagtta gtattgttct gttctgaaag
     1261 atttgagctg tcagttgtat agaaagtgtt cgaatttttt ttaagtgatt aaattagtta
     1321 attgtatgag gttctttatg atataatgtt cttaatgaat tttcagaaag gaaaacctca
     1381 aattgttcta caaatttcta ctcttcgacc tcgaccacac tcttcttgat tttgatgctg
     1441 ctgaggatgt ggctttgacc caacttctaa aagaagaagg agttgcggat attcaggctt
     1501 ataaagatta ttacgttcct atgaacaagg ctctctggaa agacttggag ctgaagaaaa
     1561 tcagtaaaca agagctggtt aacacgcgct tttctcgttt atttgctcat tttggacagg
     1621 aaaaagacgg tagttttctt gcccagcgtt accaatttta cctcgcccag cagggacaaa
     1681 cactatcggg cgctcatgat ctcttggaca gcctcattga gcgtgattat aacttgtatg
     1741 ctgcgacaaa tggcattact gccattcaga caggacgttt ggctcaatct ggtctagcac
     1801 cttatttcaa tcaagtcttt atctcagaac agttgcaaac tcaaaagccg gatgctctct
     1861 tttatgaaaa gattggccag caaattgctg gatttagtaa agaaaagacg ctgatgattg
     1921 gagattctct aaccgccgac attcaaggtg gcaataatgc ggggattgat actatctggt
     1981 ataatcctca tcacctcgaa aatcacacac aagcccagcc gacttacgaa gtctattctt
     2041 accaagactt gctggattgt ttagataaaa atattcttga aaagatcaca ttttaaagga
     2101 gacgagctaa tgactacaaa aaagctaata ttactattga agagtacatt gaaatgtctg
     2161 aagttgattt taatgaagct gttaattatg aatttacatc tgacacttgt caattagcaa
     2221 atagtattta tcaatctctt tttaagtttt ttgataagaa aaatttctct ggcgatttaa
     2281 tttttacttg gaaatctcca tcattagtca aagaagggga ttatattggg agaagggatt
     2341 cacaagtaga taatcttaga gtaataggaa atatatttcc gaattatctt actaatcgaa
     2401 aatatagcct caatatgaat cgtaatggct gtatgggaga ttttcctcat gacttttttg
     2461 atatatacct agatcatgta gcaaaatatg cctacgaaca aaaagttaat aatattaaag
     2521 agtattatcc tttaaaaaga gcgattttac accaagagaa tgcattgtat tttcgatttt
     2581 tttctaattt tgacgacttt ttagaaaaaa attatttaaa gactatatgg caagtttcta
     2641 aagaaactcc tttttctgaa atggatttta atatgtttaa aaatatttca gaaaagataa
     2701 tcttcgaaag aggtagtaaa atgcttaatg atttaaaaag taattataaa aaatagccag
     2761 tctttataaa ctgtattcac gtattcaaat cgtatatagt cgatttatta aatctttaga
     2821 taaactgtaa aaagtggttt ccatagccac tttttgctat aatagaggca gtaaaaatga
     2881 aggagtcggc tatggaacac tcgtcttggc atgctttgat taaggcgcaa ttacctgagg
     2941 gttatttcgg gaaaatcaat cagtttatgg agcaggtcta ttctcagggg attatttatc
     3001 cacccaagga aaaggttttt caggctctct tgacaacact gcttgaagaa gttaaggtgg
     3061 taattctagg gcaagacccc tatcacggac caggtcaagc gcagggcttg agtttttctg
     3121 tacctgactc tatcccagct ccaccatcct tgcaaaatat cttgaaagaa ttgtcagatg
     3181 atatcggagt taagaaatct catgatttga cagcttgggc tgagcaagga gtcttgcttc
     3241 ttaatgcttg tttgactgtt cctgctggac aggccaatgg tcatgctggt caaatctggg
     3301 agccttttac tgatgctgtg attcaggtgg tcaatcatct agatagacca gtcgtttttg
     3361 tactctgggg agcttatgca cgtaagaaga aggccttagt taccaatcct catcacttga
     3421 ttatcgaatc agcccatcca agtcctttgt cggtttatag aggattttgg ggttccaagc
     3481 ccttttccaa ggccaatgca ttcttaaaag agacaggaca agagccaatc gattggctta
     3541 gataaggaga aaatatgcct cagttagcga cgatttgcta cattgataat gggaaagaac
     3601 tgctcatgct ccatcgtaat aagaaaccca atgatgtcca tgaagggaaa tggattggtg
     3661 tgggtggtaa gctagagaga ggagagacgc cccaggaatg cgcggcgcgt gaaatccttg
     3721 aagaaacagg gctcaaagcc aagccagttc taaaaggtgt catcactttt cctgaattta
     3781 caccagattt agactggtac acctatgttt ttaaggtgac ggagtttgag ggcgacttga
     3841 ttgactgcaa tgaggggacg ctagaatggg ttccctatga cgaggttttg agcaagccga
     3901 cttgggaagg tgaccacacc tttgttgagt ggcttttaga ggataaaccc ttcttttcag
     3961 ccaagtttgt ttatgatggg gataaattgt tggataccca agttgatttc tatgaataaa
     4021 ggagaaagca gatgctacta atcaaaaatg gtcgtgtaat ggatcctaag tctggtttgg
     4081 atcaagtttg tgatgtctta gttcaagatg ggaaaattat caaaattgcg cctgagatca
     4141 cggaagaagg agcagaaacg attgatgcta ctggtcttgt ggttgctcct ggtttggtcg
     4201 atattcatgt gcatttccgt gaacctggtc aaacacataa agaagacatt catactggtg
     4261 ccctggcagc cgctgcaggt ggttttacta ctgtcgtcat gatggctaat accagtccaa
     4321 ccatttcaga cgtggagact ttgcaagcag ttctccagtc agctgccaaa gagaagatta
     4381 atgtcaagac agttgcgacc attactaaaa actttaatgg taaaaacttg actgacttta
     4441 aggcgctctt agaagctggt gcggttggtt tctctgatga cggtattccg cttgagagca
     4501 gtaagattgt caaggaagcc atggaggaag ccaaaaaact caataccttt atcagccttc
     4561 atgaggaaga tccaggtttg aacggtgttc ttggctttaa tgaaaatatt gctagagaac
     4621 atttccatat ctgcggtgct actggggtgg ctgagtacgc tatgatggcg cgtgatgtca
     4681 tgattgccta tgcaactaaa gcccatgttc acatccagca tttgtctaag gaagaaagtg
     4741 ttaaagtagt ggagtttgct caggggttag gtgcagaagt cacagcagaa gtagcgccac
     4801 agcatttctc taagacagaa gcacttcttt taacacaagg tagcaatgct aagatgaatc
     4861 caccgcttcg tttggaatca gaccgtcgtg ccgttatcga aggtctcaaa tcaggtgtca
     4921 tcacagttat tgcgactgac cacgcgcctc atcatgtaga tgaaaaaaat gttgaggata
     4981 ttaccaaagc gccatctggt atgactggct tagaaacatc cctgtctctc ggcttgacct
     5041 atttagtaga agctggtgag ttgagcttga tggaattact tgaaaaaatg acatacaacc
     5101 cagccaagct ttacaacttt gaagcaggtt acttggctga gaatggtcca gcagatatca
     5161 ctatttttga tgccaaggct gaccgccttg tggactccca ttttgcttcc aaagcagcta
     5221 attcaccatt catcggtgaa accttaaaag ggcaggttaa atataccatc tgtaagggac
     5281 aaatcgtcta tcaagcttga taggagttag aatatgaatt attttcgaaa acgtagggag
     5341 agacaagcga aatctaatag tggaatttac tgtcccgcag ctaatcgttc caaaattcaa
     5401 tatgaaacta aagaaaaagc tgaccatgcg gttcaatatg ataacggagg tttagttaga
     5461 agctattatt gtcgtacatg tgcgtgttgg catactactt caaaatctaa taaacctccg
     5521 ctaagtttga aaaactatgg tctgaaactc tttggtttag ataaatcaga atagaaagag
     5581 aagtatgtat aagacaaagt gtttacgaga gaagttagta ttatttttaa aaattttctt
     5641 cccaatcctg atctaccaat ttgccaatta ttctgcctct tttgttgata ctgcaatgac
     5701 aggtcaatac aacactatgg acttggctgg tgtatctatg gcaaccagta tctggaatcc
     5761 tttctttaca tttctaacag ggattgtgtc agccttggtg cctatcattg gtcaccatct
     5821 tggtcgaggc aaaaaggaag aagttgcgtc tgatttttac caatttattt atttggcctt
     5881 gggcctatct gtggtcttgc tggggatggt acttttcttg gcaccaacaa tcttgaatca
     5941 tattgggtta gaagcagcag tagcggcagt agcggttcgc tatctttggt ttttatctat
     6001 cgggattatc cccttgttgc tctttagcgt cattcgttcc ttgctggatt cgctgggctt
     6061 gaccaaactg tccatgtacc tcatgctttt gttactccct ctcaatagcg gatttaacta
     6121 tctcttgatt tacggtgcct ttggtgttcc agaactggga ggggctggtg ctggtttagg
     6181 aacatccttg gcctactggg tcttgcttgg gatttctgtt ctggttttat ttaaacagga
     6241 gaagctcaaa gccttacacc ttgagaaacg aattccactt aatatggata aaattaagga
     6301 aggagttcgt ttaggtctgc ctattggggg aactgtcttc gcggaagtgg ctatcttttc
     6361 agtggttggc ttgattatgg ctaagttttc gtccttgatt atagctagtc accagtcagc
     6421 tatgaacttt tcaagtctta tgtacgcctt tcctatgagt atctcatcgg ctatggctat
     6481 tgtcgtttcc tatgaagtgg gagccaagcg atttgatgat gcgaaaacct atattggtct
     6541 aggaagatgg actgccctca tttttgcggc cttcacctta accttccttt acatttttag
     6601 gggaaatgtg gccagtcttt atggtaacga cccaaaattt atcgatttga cagcgcgttt
     6661 tttaacttat agtcttttct tccagttagc agataccttt gcggcgccgc ttcagggaat
     6721 tttgcggggg tataaggata cagttattcc tttttacctt ggtttgcttg gttattgggg
     6781 cgtagcaatc cctgtggcta cgctatttga ttccctaaca gattttggag cttattctta
     6841 ctggatcggc ttgattatta gtttgattgt gagtggggcg ctctaccgtt ggcgtttaac
     6901 tgtgattatg aagagatttg aatctttagc aaaatccaaa cgctaaaaag tttgtgaaaa
     6961 aatattcttg ataagaaaat cccttgtttt cacggggttt tcttttttat tttgtgaaat
     7021 ttcttttaga aaaactttga cagtatttgc caaaaacggt aaaatagtaa ggtaagaaga
     7081 aagttagaaa ggcaagaaga tgtcaacttt agataaaaat cttttgctag aaatgttccg
     7141 taagatggaa gaaatccgtc gcatggactt aaaaattgca caattagtaa agaaagggaa
     7201 agtgccagga atgacgcact tttctgttgg tgaagaggca gctaacgtgg gggctatgtt
     7261 agctctcaat ccagatgatc tgattacctc aaaccaccgt ggacacgggc aagctattgc
     7321 taaagggatc gacctcaacg gaatgatggc tgaaatcctt ggtaaataca ctggaacctg
     7381 taaagggaaa ggtggatcta tgcatatcgc tgaccttgat gctgggaacc ttggtgccaa
     7441 tggtatcgta ggtggtggta tggggatcgc tgtcggtgca gccctcagtc agcaaatgca
     7501 aaataccggt aaaatcgttg tctgcttctt tggagatggt gcgaccaatg aaggtgtttt
     7561 ccacgaagca gtgaacatgg cttctatctg gaacctgcca gtcattttct attgcattaa
     7621 caacggttac ggtatctctg cggatatcaa gaaaatgacc aatatagaac atatccatca
     7681 acgtagcgcc gcttatggaa ttcctggaat gttcatcgaa gacggtaaca atgtcatcga
     7741 tgtctatgaa ggatttcaga aagctgtaga ccatgttcgc agtggcaatg gtccagtctt
     7801 gattgaaagt gtaacttatc gctggctcgg tcactcatca tctgaccctg gtaaatatcg
     7861 tacgcgtgaa gaagtggaat tgtggaaaca aaaagatcca atcgaaaacc tccgcaatta
     7921 ccttattgaa aataacattg caagtgccga agaattggaa gaaatccaag cgcaagtaaa
     7981 ggaagcagta gaagcttctg ttaaatttgc agaggaaagc ccattcccac cgcttgaatc
     8041 agcctttgaa gatatttacg cagactaagg agaaagagat aaaatggaaa caaaaacaat
     8101 gtccttccgt gacaccatta tccttgctat gtctgaggaa atgcgtcgcg atgaaaatgt
     8161 gttcttgatg ggagaagacg tcggtgtctt cggaggagac ttcggtactt ctgttggaat
     8221 gcttgaagaa tttggtccag aacgcgtccg tgactgtccg atttctgaag ctgccatctc
     8281 tggagcagca gcaggagcag ccatgacagg acttcgtcca atcgtcgata tgaccttcat
     8341 ggacttctct gttattgcca tggacaatat cgtcaaccaa gctgctaaaa cacgttacat
     8401 gtttggtggt aaaggtcagg ttccaatgac tgttcgttgt gcagctggta acggagttgg
     8461 ctctgccgcc cagcactcac aatctctaga gtcttggttt actcacattc caggacttaa
     8521 ggttgtggca cctggaacac ctgcggacat gaaaggcctg cttaagtctt ctatccgtga
     8581 taaaaaccca gttattatac ttgagtacaa gtcagaattt aaccaaaaag gggaagtgcc
     8641 agttgatcca gactacacaa ttccacttgg ggttggtgaa atcaaacgcc aaggaacgga
     8701 tgtaacagtt gttacttatg gaaaaatgct tcgccgtgtg gttcaagctg ctgaagaatt
     8761 agcagaagaa ggaatttcag ttgaaattgt tgacccacgt acccttgttc cgcttgataa
     8821 ggatatcatc ataaactcag tgaagaagac tggtaaggtt gttctggtca acgatgccca
     8881 caaaacaagt ggctatatca gtgaaatttc agctattatt tcagaatcag aagcatttga
     8941 ctatctagat gcaccaatcc gccgttgtgc aggagaagat gtgccgatgc cttatgcaca
     9001 aaacctagaa aatgcaatga ttccaacagt tgaaagtatc aaagatgcaa tccgaaaaac
     9061 ttataacaaa gaatagagtt acataagata agttatgtaa ataaaataaa gctgacgaga
     9121 aactttgtat cttttaggtg cagagctctt cgtcattaat atcttatatt cgagcacggg
     9181 ctaaaagctc ggaaaaaaga taaatctcct tggcttcatc gaagccatcg tcgatttcct
     9241 atttttcagt cgcttttgac gccctttgta tcataaatag aattggagag gtcatggctg
     9301 atgacaagct aagagcgact cctgcagcta gaaagttagc ggatgattta gggataaacc
     9361 tctacgacgt ttctggctca ggtgcaaacg gtcgtgtcca caaagaagac gtggaaactt
     9421 ataaagacac aaacgtggtt cgcatttcgc cacttgcaaa acgaattgcc ctcgaacata
     9481 acattgcttg gcaggaaatc caaggaaccg gtcatcgtgg taaaatcatg aagaaggatg
     9541 ttttggccct gcttcctgaa aatatcgaaa acgatagcat caaatctcct gctcagattg
     9601 aaaaagtgga agaagtccct gataacgtaa caccatatgg tgaaatcgag cgtattccaa
     9661 tgacaccaat gcgtaaggtt attgcccaac gcatggttga atcttacttg actgcgccaa
     9721 ccttcaccct caactatgaa gttgatatga ctgaaatgtt ggctcttcgt aagaaggttc
     9781 ttgagccaat catggaagca actgggaaga agactactgt aacagacctt ctttcgcttg
     9841 cagttgttaa gactcttatg aaacacccat acatcaacgc ttcattgaca gaagatggca
     9901 agactattat cactcacaac tatgtcaatc ttgccatggc agttgggatg gataatggat
     9961 tgatgacacc tgttgtttac aatgctgaga agatgagtct ttcagaacta gttgtagcct
    10021 ttaaggatgt tattggccgt accttggatg gtaaattggc tccaagtgag ttacaaaatt
    10081 caacattcac aatcagtaat ttgggaatgt ttggtgttca gtcctttggc ccgattatta
    10141 accaacccaa ctcagctatc cttggtgtca gttcgacaat cgagaagcca gttgtcgtca
    10201 atggtgaaat tgtgattcgc ccaatcatga gtttaggatt aaccattgac caccgtgtcg
    10261 tagatggtat ggctggtgct aagtttatga aggacttgaa agagttgatt gaaaccccaa
    10321 tctcaatgtt gatttaagag caagagtatt catttttaag atatagataa aggaaggaag
    10381 acatggcctt agaaataatt atgccaaaag ccggcgtgga tatgacagaa ggacaaatcg
    10441 tccaatggaa taaaaaagtc ggagaatttg taaaagaagg agaaatcctt ttggaaatca
    10501 tgactgataa agtcagcatg gaattggaag ccgaagaaga tgggtacttg attgccattc
    10561 tcaaaggaga tggtgaaact gtccctgtaa cggaaattat cggttacctt ggtgaagaaa
    10621 gggaaaacat cccaacagct ggagcagcat cgccagaagc tagccctgta cctgtagcaa
    10681 gtacctcaaa cgatgatggt aagagcgatg atgcttttga tatcgttgtg attggtggag
    10741 gtcctgctgg ttatgttgca gccattaaag ctgcccaact cggcggtaag gttgcccttg
    10801 ttgagaaatc tgaacttggt ggaacctgct taaaccgtgg atgtattcca accaagacct
    10861 accttcataa cgctgaaatt attgaaaata tcggtcatgc tgcaaatcgt ggtatcgtga
    10921 ttgaaaatcc taacttcact gttgatatgg aaaaactttt agaaactaaa tctaaagttg
    10981 ttaatactct tgttggtggt gttgcaggac ttcttcgtag ctacggagtt actgttcata
    11041 aaggaattgg tacaatcact aaagacaaga acgtcttggt aaatggttct gaattgcttg
    11101 aaaccaagaa aatcattctt gctggtggtt caaaagtcag caagatcaac gtccctggta
    11161 tgcaatctcc acttgtcatg actagtgatg acattcttga aatgaacgaa gtgccagaaa
    11221 gccttgttat catcggtggt ggagttgtcg gtatcgaact cggtcaggcc ttcatgacat
    11281 ttggttcaaa agtgactgtt atcgaaatga tggaccgtat agttccagct atggatgcgg
    11341 aagtttctaa gaaccttcgc ttgatccttg agcgtaaagg aatgaccatc ttgactggta
    11401 ctaaactgca agaaatcatt gaggaaaatg gtcaacttcg tatcaaggtt gaaggaaaag
    11461 acgatatcat cgcaagcaaa gctcttcttt caattggtcg tatgccagac cttgaaggta
    11521 ttggagaggt tgagtttgaa ttggatcgtg gttgtatcaa ggtcaacgaa tacatggaaa
    11581 cttcagttcc aggcatttat gcaccaggtg acatcaacgg tactaagatg ttggctcacg
    11641 cagctttccg catgggtgaa gtttccgctg aaaatgccct taaaggaaat catgcagttg
    11701 ccaaattgaa tttgactcct gcagccatct acactctccc tgaagtagca gcagtaggtt
    11761 tgacagaaga acaagcccgt gagaaatacg atgttgccat cggtaagttt aactttgctg
    11821 ctaacggtcg tgctattgca tctgacgcag ctcaaggttt cgtaaaagtt atcgctgata
    11881 agaaatacgg agaaatcatt ggtgtacaca ttattggtcc tgcagccgca gaattaataa
    11941 acgaagcatc aagcatcatc gaaatggaaa tcactgttga ggaaatgctg aagaccatcc
    12001 acggacaccc aacttactct gaagtgatgt atgaagcgtt tgcagatgtt ctaggaatgg
    12061 ccatccattc acctaagaaa aaataaaacg aagatagatt agactggaag gttatttcca
    12121 gtctctatca tataaagtaa agggatatca tgaaatacat tatcaatcat tcaaatgaca
    12181 ctgcttttaa tattgccttg gaagaatacg cctttaaaca ccttttggat gaggatcaaa
    12241 tcttcctact ttggattaac aagccatcta tcattgttgg tcgtcaccag aacactatcg
    12301 aagaaatcaa ccgtgattat gttcgcgaaa atggtattga ggtagttcgc cgtattagtg
    12361 gtggtggagc tgtttaccac gatttaaata acctcaacta cacgatcatc tccaaagaag
    12421 atgaaaataa ggcatttgac ttcaagagct tctcaactcc ggttatcaat accctggctc
    12481 aactcggggt taaagctgag ttcacaggtc gtaatgacct tgagattgat ggtaagaagt
    12541 tctgtggcaa tgcccaagcc tatatcaacg gccgtatcat gcaccacggt tgcttgctct
    12601 ttgacgttga tttgtcagtc ctcgcaaatg cccttaaggt ttcaaaagat aaatttgaat
    12661 caaaaggtgt gaaatccgtc cgtgcccgtg taaccaatat tatcaatgaa ttaccaaaaa
    12721 aaatcacagt cgaaaaattc cgtgatttac tcttggaata catgaaaaaa gagtacccag
    12781 agatgactga atacgtcttt tcagaagaag aattggccga aatcaatcac atcaaggata
    12841 ctaagtttgg aacttgggac tggaactatg gtaaatcacc tgaatttaac gtccgtcgtg
    12901 gaaccaaatt cactagtggt aaggttgaag tctttgctaa cgttactgaa tcaaaaatcc
    12961 aagacatcaa gatttatggt gacttctttg gtattgaaga cgttgctgca gtagaagatg
    13021 tccttcgtgg ggtgaaatac gaacgcgaag atgttcttaa ggcgctaaaa accattgata
    13081 tcacacgcta cttcgctggt attagccgtg aagaaatcgc tgaagcggta gttggataaa
    13141 tcaaaaaaag aagttggcca acttcttttt ttgatattta tttacataat ttaaaatacg
    13201 tgaaatcata aactatctag agcattcttt tgttcatcat taacaatatg ggtatagagg
    13261 tcagtgactt gtgtgctggc atgtcctagt tggtgactga ctaaaacttg tgatttagtc
    13321 gcatcataga gcctagttgc tagcgtatgg cgcagtttat ggggtgttac acgtacttta
    13381 aaatcctctg agtatttagc aaccattttc tcaacgctag aagcatcgat acgattagga
    13441 acacctctgt agagagttaa aaaaagggct gtatctgttt tttccgtttt atagcgttga
    13501 ttccgaatgg ccagataatt ctctaaataa ggtttagcaa aagcagcgac attgactgag
    13561 tcacgtttgc caccttttcg agtaacatca ataaccatca tttttagatt gagatctctt
    13621 agatctagat taacagcttc agataagcga acaccagatg ccaagagaag ggcaataatg
    13681 gctaaatctc gttctttatt tttgttgaat gatgagagag ctcgatttga aagctgttgt
    13741 gggtgctctt gatcgatata agttagaaaa ccttctgttt catcacctag aaagagtttt
    13801 tgcttgatat tttcagctct ggcagcaagg gtttctttct ttttcttggt tgaaactttt
    13861 ttcattacat tacgatagaa ataaggttcc ccctgatcgt tttcaacctc ctcggttaga
    13921 tacttgtaaa gactagaaag tgctgataag gttcgattga tagttgtctg tgaaacacct
    13981 tgttttgttg tattagcatt cagcaaggga cgttcacgta gataaaggat aaaggattcc
    14041 atgtctttct tagacatatt ttccaaaact gataaaggaa tatcggatat tttatcagcg
    14101 tttgaaatac cagactccaa aacccagctg aaaaatcggt catattcctt aaggtattcg
    14161 tacagggttg taaaactgta gggcacagcc agcttagatt ggtagtattc cagaacatac
    14221 cagggcatga gttgttttag tttgtcgatt cgttccagta aaatctcacg tttcatgtat
    14281 tttctccata agtaagtata ctagtagtat agcatagact tgtatatttt tcaagaaaat
    14341 tatagttttt cagaaagatg ttataggagt ttttcaaagt gataaaaaga cttagaccta
    14401 caaacaaaac agaataagga aaataataaa aatctcaccc actaaacttc tgttaatact
    14461 acataactga agagctatat aaggagctat gagatacaaa acacattgta taatagattg
    14521 aaactagaat agtacatctg gacttctaaa acattgctag aaattgattt gattgttctg
    14581 attgttttat cctatttcta tttcatttca ctatataatt gctattgttt tctttttcat
    14641 gattttaatc ttactgtaca gatttgatac agtaaactcc tttctagctt tatactttat
    14701 catttctaac ttaattatag tcttattttt aataaagttc aattatttat atgtaaaatt
    14761 cctcatcagt aaaaaataac cgatctcatt tctgagaatc ggttttctaa ataaatcaag
    14821 ctgagtattt acataacata aattatgtaa atactcatac tacaacaaca aatctttgac
    14881 ttttccaatt tcactttttg gaataaccag gtgaatcata tcacccagat acattctggt
    14941 tgagccgtta actgtttggc tcttgccatt atggacttga gttgtgatga ggacgttgtg
    15001 tggtaagttg agttcatgaa cttgtttccc agcaatttta tcagaaactg gtatttcgat
    15061 aagtgtaact tctccttcgc tagatacttc ttctggaagc attttttcca gcatggcttc
    15121 atagactggc gtacctttga gcaaatccat gataatataa gaaacaagag tgacaagacc
    15181 aagtggcatg aggttgcgaa tatctcctac catctcagtt acgaggatca tagcggttaa
    15241 gggagctttt gatatggctc caaaatagcc actcattcct agaatgacaa atatagggaa
    15301 ttgctcttga ctgacaagtc caagattgac acagataaca ccaactaagg aaccaagcaa
    15361 agaaccaaga gctaaaatgg ggaggaaaat tcctcctggc agtccacttc catagctaat
    15421 catactccaa ataaagcgga tcaaaaagta agctaataaa acttggaaac taaaattttg
    15481 ttcagttaaa gaaaggacaa gctgatttcc gccaccaatg atttgaggta agaagattcc
    15541 gactggtatg ataatgataa aagccaagat gggataataa gccctatcca aatggatttt
    15601 ttgaccaatc aagtcataaa ctcttccaac gtttaataca gctttctcat agagaaaacc
    15661 tgaaaatcca aggaaaattc ccatgacgag atatatccaa tactggtcta gggtcatggg
    15721 aggaatgtta tctggcatat ccaatactgg tgtcaaaccg aacatgagta gagacacaaa
    15781 gtttgctacg atgctggctg ctagagttga gacccagaaa aagcgcgaaa aatggtgata
    15841 gacttcttct acaacaaaga gaagtgctgc aataggagca ttaaaggctg cggctaaacc
    15901 tgctgcagct ccactggcaa tcaaggaacg ttcctctact ggactggatt tgagccactt
    15961 ggcaattcct ttaccaccaa ctgctccaag ttgaatgctg ggtccctctc gacccagcat
    16021 gagtccactg gcaatagcaa gaatacctag cacatatttt ttccaaagaa tgccccacca
    16081 gttgagggac atgaggcctt tcagttcggc ttcgacttga ggaattcctg agcctttaat
    16141 atctttttct gaccgtgtta gtttggcact gagccaacag atgagtatat aaaacaaaac
    16201 cagtacaaaa agattgcgca ctaagtaccc ttgatcttga taaactcctt gtatcaggtg
    16261 gaagcccttt tcaattaaga aacgaaagga tccgacgata attccaacga tgaggccgac
    16321 aatgattcct cgaccaactt gggatagtat agtgctggat gcaaaggcga attctttctt
    16381 agaacggact atttccgact gttcctccat ggtatttcct ttcaattaac tttctttttt
    16441 acctaaaacc agtgatttaa cgggttcaaa gctggttcgg tgaattgggg taactcctag
    16501 ttttgtgagg ccttccagat gtttagctgt gccatatcct gcattagtag cgaaatcata
    16561 gccagggaac tgctgatcgt attccttcat caattcatca cgtgttacct tggctactat
    16621 agatgctgct gcgatagaga gggagttggc atctcctttg ataatggagg tttgtgaaat
    16681 gggcaagtcc agtttcatgg catcaatcaa aaggtgctct ggttgagggc tgagctggga
    16741 gattgcttct tgcatggcta gtttggttgc ttcatagata ttgacttggt cgatgacctg
    16801 attatctatg ataccaattc caatcgacaa ggcttggtct tgaacgactt ggaaaatctc
    16861 cagatgtttc tttttaggaa ttttcttgct gtcgttgaga cctttaatct tacaattttt
    16921 aggtaaaata acggccgcag cgactacagg accagcaaga ggaccacgac caacctcatc
    16981 aatacctgca attaaggtca atccttgctt ataaagttct ttttcataag aaagcatgga
    17041 ttccaagcgc aaattttcat ctaattcagc ttgaatggct cttttatgct tgctgatttc
    17101 cttttgaact cctgagcgat tatccttttc aagatctaaa aaaatagggc tttctaactc
    17161 cttgactgtc acaaggagtt ctttgatttc tttaatcgtt gccatcgagg ccttccaatg
    17221 tatctaaggt atagttaccg agtttgccat cacggacttc cttcacgaag agactgtaaa
    17281 aacggtcata gtcatcacgg aaaccgaggg cgcgggtcat atccataata atcacaggcg
    17341 cttcttcttc aattttcatt tgtttgaagc gttcagccag cttttctgga taatgttctt
    17401 tgaaataatt gataccaaaa atggtaacct catccatagg aagcaactga tccttgatag
    17461 ctccagtcaa tgccaactta agtgcaacag tttcatcctc aaacttaggc cagagaatcc
    17521 ccggtgtatc caagatttcc agatctttat tggttttaag ccattgttga ccttttgtga
    17581 cccctggctt gtttccaaca acagcaatct ttttaccagc caaacggttc atcagagttg
    17641 atttaccagc gtttggaatc ccaataatca tggtacgcaa ggtttcaatc tgaatcccac
    17701 gttctttctg gcgagcaatc ttatcagcca tgagcttctt ggccgcatct gttacaactt
    17761 ttacagtcac ttgctctttg gagttgatag ctagcgtctg gattccttgt gattcaaaat
    17821 actgacgcca ttccttggtc attgctggat cagccaagtc ggccttgttt aaaatcaaga
    17881 gttttggttt atcaccaaca atcttggtta acataggatt ttgactagat agaggtaagc
    17941 gtgcatcaac taaaatcgtc acaaaatcaa caaattttaa attctcctgc acctgtcgac
    18001 gagctttaga catgtgacca ggaaaccatt gaatagtagc cattgagttt tttcctttca
    18061 tagcaaggat ttagatcccc tattttattt tactattgtt tgaacataga gagttttcaa
    18121 atgaatgatg tccaaacagt tcttgtttta tgacatagaa atctacttta tattatatca
    18181 tgccttcttt attttgtccg atgatagcct tttaccctat atagaaaaaa gccatcaaat
    18241 gatgactttt cagagggagc aaaaaactgt tcccgtcata ttatgaacca aaagaactaa
    18301 actaccaaca gctaataggc ctaaagctgt aagtgcagaa gttgatgaac ctgttgcagg
    18361 aagagtttcc tgctgataaa taagagcata acttacttca ttatcagtag gaattcctgc
    18421 ttgaatcttg gtttgttctt catcaccttt ttaaacttta tttcctaata gtaaacacta
    18481 ttttttattc tcaaaaattg aacttctaaa atcatttgtt tggtcaagat aggctttaaa
    18541 gattgctctc ttcaacttat gaacggcact gtcgatttct ggatcataat tactccaacg
    18601 tggaccttca gcatccttga gaacagcttg gtccatgagg gcttgcaatt catccacatt
    18661 attgatagtc tttgtgccat agcttggcca tggttttgtc ggatctttaa aggtcacctg
    18721 cttcaagttt ccaaactgat ccactcgttc ttggtacata gctgtcttaa attctgccca
    18781 agttttatac ttaccgtcaa ataccttttt caaaacaagc tcatcggtca ccaagccccg
    18841 ttctttacca taaagattga tagtttgccc ttgttgttta gcatcttctt cgtattggtt
    18901 tgagatataa ggtaccattc catccttaaa gcctttggca gccaaaagtt cgtacgcaat
    18961 cctacgtccc ataaggtccc ctggtgtgcc tttctcactg ctgagagctg aatagattgg
    19021 ggcaaagagt ttgatggtat agtagccatt tcgttcatag tcgccagact ggtactcacg
    19081 agctgataag atgttgtggt caatcaaact ttcaaaacta ttcaggtttc gggcctctgc
    19141 ttctgtcaat tctttgacta cgttagtggc ataaacctca tttccatctg ctggatcttt
    19201 cacatacttg ttctcaattt ttctgagagc cgccattttc tggtaaacac ttagtttatt
    19261 aacgattgac tgcccttcga gatattccat catgtagata aggtcaaaca tgttatggac
    19321 atagttctga agatctgctg cgttttggaa tctctctgtc ggatccaaga cttgaagacg
    19381 ggatccctct gtactatctg attttgagtg tttcaagata gaattaatgg taatggttgc
    19441 gtcacttggt tggtcagggg cttgcaataa gccttttgcg aagaactctg gtcccaagcc
    19501 atttcttcga ccatagccac caaggtaaat atcctgatcc gaatcatggg tcatttcatg
    19561 ggtataagta atggctccat ccttgtccag catgcggtaa gacatatagt agacgccgtc
    19621 ccctgtagcg taggctccat gctggttgtg tactacctta ttgccaactg gtccaaagaa
    19681 gttcttcata gctggattgg agctatcaaa cttagcctcc gctgtagctt ttcctgatgt
    19741 tgtgtcatcc ccaaacttat aggcatcata aaggagaatc gtacgataga gtttttcgcg
    19801 tgactgttca tctaaaatac gataccaata atcgtagtga tctcgctgac gtttggctgt
    19861 ttcacgcgca ttttcttcaa caaaatcatt gagagccttg cccgctttat ggtcactact
    19921 gcggtagcga tcataagctc caaatcctag actagacatg gtcgagatga caaatacgga
    19981 tctctctggc aaggtcagga gaggcaagac catattgcgg tatttccatg tggcactcgt
    20041 gatacgatca taaacaccga tagaatactt ggtgccagct aacccttgct tcgttttcac
    20101 ctcttcgata gtggattttt cttcgacaat gtaagcctta gtctctgatt taaaccagtc
    20161 attattgctt gtatttggta aaaagacttt tcggtaatgt tccagcgtgc taaacaaatc
    20221 tgtcgttcca tgttgactgg caagactgat accataagta tcgacattat tcttagctag
    20281 aagattgtta aagccagatt tacctaactc aatcagagta tctagtgggg aagtatttcc
    20341 tttaccaaag aagtctggat gatacataac taggtctttg acattcactt gaccatagtt
    20401 aaagttatac caacgttcta aataagttaa accgagtagc aaggcttcct tattattctt
    20461 gattttatct acaagatagc ctctggtgac tgagttatcg ctagctagac cggcatctgc
    20521 tgacaaaagt tttttcaagc tgtctcccag attttgtttt gttttggaga actggtcttc
    20581 taaatagagc tcggttaact taacttctgg agaaatacca agtgtctttc tgatagcatc
    20641 tgactggtaa tcaagcttct gcaactcagg caagacttcc ttaacaatag agtctcgatc
    20701 atataagaat tggttaggag tgtagagaag tcccgtatta cctagattat attctgctag
    20761 attggcaaaa tcagtctggt acttgagatc aaatttctca gatgaatggt cattatagtg
    20821 aagtaagagt ttgtttgcag tctgtttgtt ggaaacaata tctgtgatta cttggtcatc
    20881 cttcatcata actgcagata agagttcttt ttggtataag agactgttct ccttaaccag
    20941 gtttccgtat ttgacgatgg ttgacttatt ataaaaaggt aacaattttt caatgttctt
    21001 ataaaccaaa gcacggttag cttgataatg ggctatctta gaaaaatcac tgtctttctt
    21061 gccacttgtt gagaggggtt ccaccgttgg tagagtgaga ggatttattt ctgctttttt
    21121 gcttacaatt tgagaagcat ctagcattgt tcctctttct tcaaaggatt ccttgctgac
    21181 gacctcatcc ttctctaaag tgacattgaa aactctatta gccttactac taaatgtatt
    21241 agctaccttc attcctgtat agtggtatcc agtgatggca tttccgtttg ttacattgac
    21301 atcgctaaga acattggtca attcaccagc gtgtttttcc tcaccagaag ttcgatccca
    21361 caaatatcct gccacaccag cgactttacc aaagtgcttg acattattaa tatcaccttc
    21421 cgcataactg ttctgtatat gcgcatcttg gtctactaga cctgcaagac caccgacagt
    21481 ctgatctgac ctattggtgt ttgacgaaat ggttactgtc gctttggatt tagcaataga
    21541 cgcatttttt cctgttaaat gaccgaccag accgccaata ttgtaggcat cagtcgtttc
    21601 ataggtattg acaattcttc ccttgaaact gctctctgcg atgcttgatt ggtctgcctt
    21661 agccaacaaa ccaccgacac cacgttctcc agccagaaca ccatcaacat gaacttgttt
    21721 aatctttgtg ccattcgtag cttcatttgc tagtgaacca atatcatttt tccctgaaat
    21781 agcaacattt tttagactca gtttttctac tgtagcacca ctcaagtttt caaacagagg
    21841 ttttttcaaa ttatagatag cataattctt gccatctttt tcaccgatta aacgaccagt
    21901 aaaggtgtcc ttgatatagg atctttcatc aggaccaagc tccacttcgt tagcattcag
    21961 gctggccgct aaatgatagg ttccagaggg attttggttt atagctttga ccaggttgct
    22021 aaaggaagta aagtttgtat tttcctcttt agccttctta tcgaggtaga aggtgaaatt
    22081 gtcgacatat ttattttcta gttcttgctg gagtttctca gctttggctg tgattttata
    22141 aactgactgc ccatttcttt tctcttcagt tattgaagct actggtatat agacatcttt
    22201 aaatgctgaa gattttacct tgacaaagta agtatccgta ttctctggaa ttccatccaa
    22261 tgaaacatgt tgtctgtagg ttccattcgt ctgactatac aactcaatat cagaaacatt
    22321 tcttaattcg agttttttct ctggttctgt ttgtccattc tctgatgttg tattacctga
    22381 attttctggt tttgttgcag ttccgttttt ttctggttga tttgattctt caactggtgg
    22441 ttttgaatca ctaggtttat tggatacttc tccagtattt tcgttagcta ttttcccaga
    22501 gtttgtttgt gtttcttctg caggttgaac tggtttttct gtttcttgat ttgaggtacc
    22561 ttctactgtg ccttcatttg gatttactgg aacttcttct acagtttttt ctgaattttc
    22621 atttttagag tcattatgtt ctggtttatt tgattctcca actgaggttg tcgaatcact
    22681 aggattactg gacacttccc cagtattttc gctagatgta tctggtgata ctttctctga
    22741 attcgttgtt gattcttctg caggttgaac tggattttct gcttcttgaa ttgaggttcc
    22801 ttctgtagta ccttcatttg gatttactgg tgtttcttct gttggtttta ctggaacttc
    22861 ttcagttttt tctggacctt gttctttggt cttctcaacc ggagtttcag gttttacttg
    22921 ctcaatatta cccttatatt ctggcaatgg ggctacctgc tctggttcac ctttatcact
    22981 taccacagta tctggcgact ctggttgaac ctcagtctca cctttgtcgg tcacaactgc
    23041 ttcgggtaat gtcggttgaa cttctggttc gcctttatca cttactacag cttcgggcaa
    23101 ctcaggctga attgcgggtt caacaataga tccagactgt acgtccttat gttctacacc
    23161 agtctcaggt tgttccttta taacttgagt ttttttagta cctttttcga ctattcttgg
    23221 actaggcgca gtcgttgaag ttgaaacaat ttctcgcgaa acttcttcct tgtttacaga
    23281 gaatattctg acgatttcaa ctttcttacc taatttacct tcttgtttta ctcttacagt
    23341 tccttcagct aaatcaggat tttcttgaat ttcttcttga aaatctattt ttgtctctat
    23401 agtttcctca cgatataaga gttcaggttt gttcaattga cctgataaaa cttcatcctg
    23461 tggatttaat gtatttaccc cagtcttttc ttttggagaa atcttctcct ctttcttcgt
    23521 ttctagattc ttatgttcgg ctaattgttc ttgagaatct gaagattgtt tctcttcttt
    23581 tcttggattg attaattcag tagagaaagg tttttcaact acttgaactt ctgtcggctt
    23641 agttgaagaa acaggtgttt gttcctgaat agcttgtact gttgatggat ggtctacaaa
    23701 atttggtgta acattataat ccaccttttg ttgttttgta ggagtggctg ctgatttttc
    23761 ttgattactt acttcaaaat cagaagtcgt ttttccctct ttgatatatc caatataagt
    23821 gtaacctgaa atctctttag gaagaggtaa tttttctcca gaggtcaatt catagtccgt
    23881 attgtaattt agcaaaagat gattttctaa agcatggact gaaactaaga caccatttcc
    23941 cattcccgca accaatacta aatgtaatac cgttttattc ttaacctttt tcttggaaac
    24001 agcaaaaatt aaaattccca gagcagctaa gctagcacca gcaactaggg cttgcctctc
    24061 attcttgctt ccagtatttg gtaattccgc cagttgattt tgagaattta acttataaac
    24121 aagataataa gtttcatcat cattctccac gtatgtcgga atatcataga caagctgctt
    24181 cttttcttct gatgatagct ctgaatctgc cacatattta tagtgaactc ccgcagtttc
    24241 ttgagcatcc acagatgaac tagctaatac agacataaaa aataaacttg aaatcgttgc
    24301 agatacaagt cctactgata attttctaaa tgaaaaacgc tcttgttttt caccaaaata
    24361 cttttccatt attcctcctt gaaataaaat ttatatatgt tacaaagacc tttattatat
    24421 tagtgtatta tctattatct atagaaaagg cagtatacct taattatact cttaatttac
    24481 aaaaaagtct taaaattgag atgcgctttc atactttgtt ttatattatt tgggggtaca
    24541 ataacaccta ccatgaaatt tacacggtag gtgttactca tatcactaat cgttctaaaa
    24601 atggtttgag gcagttgagg agaattcctt ctatccagct tccttgtgct gatgagcgat
    24661 ggtcttcctg caggcttttt tttagaaaat ctcggacttg ttctggtgcg atttcaaatt
    24721 caaaggcttt cattttatag aaaaagtcga tgagatgatc tgacaggtat tcagttgaaa
    24781 agggtacttc accacttttt cgatattcta ataagagtct agaaaatcga gctttttctt
    24841 caggaagctc acgaaaatag gaattgagga tccaagtctg cttctgtttt ctttcaattg
    24901 gatcctgact ggcaattcgt tggtcttttt ccagctcttt ttggtattgt ttggccttga
    24961 tagctcgttc tgctctattt ttaccaaaaa gaattttttc ccacttgcgt tcttcttgag
    25021 tcagggtctc tgtaaagcca aagtaatctt gataagcacg ctctgcgggt cccatggcta
    25081 gaaccagatt gtctgcatat tgcttggcga ttttatccct cttcttgcgt tctttctctg
    25141 cctggatacg gagttcttgt tcgtagtcaa ttttctcctt gcctagcttg acaaggtaga
    25201 gttggtcatc cgatttccca agtaaaaagg gtttgataca cttttcaagg acttcttcca
    25261 tccgagcctt tttctttggt tccgccttgg tccaacttcc tccctgaaag acttctagga
    25321 aaagctggta gtctctctca ggcgcaaatt gattgccacg attgggtttg aaaacacctt
    25381 tttcccagag ccattttaga agtcgctcgt caaagtcact tttattgacc ttgatttttt
    25441 cctttttctg agcttttctg gttagatttt caacctttct gagcagtttt tcttcctctt
    25501 ccaattgctg gtcaaggggc aatcgatgaa aatgacgaac acagtcgcta ccaattggaa
    25561 agaggcgttg gcctgtgaca ccgttaaaga gttcataagc gtatttgatg gcatttcgac
    25621 agacacaatt gctacggcca ataccgttaa aaatcaagga aacttcattc cattccttgg
    25681 tagcttgttc ccaagtatcc gctttcgaag cctgtaaaac tgcatcgtgc agggattttc
    25741 taactggaag tgtcatgagg tctcctttct aatactcaat aaaaatcaaa gagcaaacta
    25801 gaaagctagc cgcagtcagc tcaaaacact gttttgaggt tgtagataga actgacgaag
    25861 tcagtaacca tatatacagc aaggcgaagc tgacgtggtt tgaagagatt ttcgaagagt
    25921 ataagttata cttttacaac ttgaacctcg tctttaccga gtaaaatcaa gtatttttca
    25981 atattttcaa tcgaataggc tcgtgataaa gcctcttcgt atagagctaa ctgaccacga
    26041 tagcggtcta cgagttgact tggttcatca tagcggtctg tcttgtagtc gaacagaaca
    26101 attttgtttt cgtaaagcag atagccatca aggataccac ggacaacaaa gtcttcctga
    26161 ctcttttggt ctcgtttgag catggagaaa ggttgctcgc gatagagatg gtcggtatta
    26221 gcaagaattt cctgaccgag tgctgtgtca aagaaagcaa gaattttatc aagattgatc
    26281 ttgtctctga cagcttggct agtttgaact tgtttgagtg tttctgttaa gctagcaagg
    26341 gttagttgct ggctgaggtc aattatctgc atgagttcgt gagtagcact accaatctca
    26401 gctccagtta ccttttcttt ggttgaaaaa tctggcaaat cgaagctgat tttcttgcct
    26461 actgactgac cttgaccagc aatctcgaca ccttccatat ccataactgg ttcgtagaat
    26521 ttcttgattt gacttggggt ttgaacacta ggaagttcaa tagctgcgcg gtgaagagta
    26581 ttataaactt ccacctcctt cagcatttcc agagcttctt tgatggtatc tgactgacga
    26641 ttgtctgctt gggagctatc ttggagagga ctcttggttt ccaactctcc gatagcttct
    26701 ctggtcaact gatcttcgtc aataaaacga taactaaagt tgagcttgtc cttagtaaac
    26761 actttactga tagcccaaag ccaatcttgg aaattccgtg cttgcagtct agtattgcta
    26821 tttagtttcc catttttggc tgctgggtat tccttggatt ccagcttttc acgagaaccc
    26881 ttgccgacaa gatagagctt tttctcagcc cgcgtcatag caacatacag caaacgcatc
    26941 tgctcagaat agcttgctag ctgtaattcc tcttcgttct gcctataggt cagactagga
    27001 atggagagtt tgatggtttt aggatagtgg tcttctactg cccctgtctc catcttggca
    27061 atatatttga caccaagacc attctgacga ctgagaatga cttctgacat agagtcttgc
    27121 ttgttgaaat cttgatccat attgaggata aagacgtaag gaaactccag ccctttactc
    27181 ttgtggatgg tcatgagctc tactgcatct tttggcggtg cgacggccac gcttgccaaa
    27241 tcgtgctggg cttctaagac ttggtcaatc atacgaataa aacgcgacaa acctttgaaa
    27301 ttgctctttt caaattgatc agcacgcagt gctagggcat agagattggc ctgcctagca
    27361 ggaccattcg gcaaagcccc aacatagtca taataaaaac ggtcgttgta aatcttccaa
    27421 atcaagtcat agagagagtg ggttttggca tacaagcgcc aagaagctag gatatccatg
    27481 aattgcttta gtttttcaac tagagctgtg tgaatcaagc ctttttgact acttgccatt
    27541 ttttgtgcat tgaccagttt ctcatagaga ttttcgtgga ctttatcctc tgctttctga
    27601 agggacaaac gtgctagctc atcctcatca aaaccaaaca ttggagactt cataagggca
    27661 accaaggcgt agtcttgcag gggattgtga atgacacgaa gagtgtctag catgacttgc
    27721 acttctaggg attggagata attgttttgc tctccgtcag ttttgacagg aatcccgtac
    27781 tcagacaggg cgaggagaat ctggtcatta cgactgcggc tggaggtcag aagggcaatt
    27841 tccttaaagg caacaccttt ttcttgatga agtttcagaa tctccttgat aactaagcgc
    27901 atttcgcctg ttagtttcgt ttctgtttga ctctcttctt cctcacctgt atcgtccttg
    27961 tcgtagagga gaaattctgc cttgttgtct ggattgggag tcagtttggt attggcaaaa
    28021 acaagctggt gcttgttatc atagttgatt tcaccgacct cttggtccat gagacgttca
    28081 aagacatcat tggttgctga cagcacttct gaactactac ggaaattttc cttgaggaga
    28141 atgagcttgc cttcttgggg attttgcgca tagcgttgga atttctcatt gaaaatctgc
    28201 gggtctgcct gacggaaacg atagatggat tgcttgatat ctcccaccat aaagcgattg
    28261 tggccattag acaacaattc cagcatccgt tcttgaatat ggttggtatc ctgatactca
    28321 tcgaccatga cttcatggaa gcgctcctga taagactcac gaacttgtgg gaaattctct
    28381 aaaatctcaa tggtgtaatg gctgatatca gcgaattcaa aggcattttc ctggcgtttg
    28441 cgctgacgat aagcctccac aaaatgactc ataaaggttt ggaaggtttt agctagtttc
    28501 catgtgtctt gatgataacg ttcttgatag tcgagaatgg ttatctggtc tgataattgt
    28561 cctagtttag caaactgggt ctttctctct tcgttgtagg catcagccag gggcttcaaa
    28621 tcagccttac gactggcatt agtcagagct cgaccgtttt tctccttaga gatggcgaca
    28681 acacgcgcaa gcactgcctg ataagcctga ctatcggact cctgatttag ggagcaaatt
    28741 tcatccagaa ttaactgaac attttctaaa taggcagcct ttgcaaactc cttggcatcg
    28801 ttatccagat ggtaacggaa aaagctttcc aaatcccaaa gggcttgttt gatttgctca
    28861 gtcagttttt ctttttcact ggtaaaatca gctttctcaa atcctttgag gaaagattca
    28921 ctcagccact tttgaggatt actggtggat tggaggaagt catagatttt atagacctgc
    28981 tggcgcagac cccgttcgtc cttgccacgc ccagcaaagt ttttcagcaa atgactaaag
    29041 gtctctttct gtttaccttg gtaatgcgct tcaaagacct catgaaagac ttcgttttcg
    29101 agaagaagtt gctcgctttg gttttgtaaa atacggaaat taggtgcaat atcaagcaga
    29161 taaccatgtt tgccaaggaa tttttgtgtg aaagagtcca tggttccgat ggcagcgttt
    29221 ggtaggtctg ccaactggcg tcccaagtgt tgtttgaggt cgacatcatc tgtttcttgg
    29281 attttcttgc tgattttttt ctctaaacgt tctttaagtt cagttgcagc cttgacggta
    29341 aaggttgaga taaagagttg agaaatttcg acaccacgcg ccaattggtc cagaatgcgc
    29401 tctgccatga caaaggtctt tccagaacca gccgatgctg agaccaggat attctgacca
    29461 gaagtgtaga tagcttcgat ttgctcggca gttttctttt gttccttgct cgaatttgct
    29521 tctgcttctt gcagtttttg aatctcctcc tcacttaaaa agggaataag cttcatcgat
    29581 tcaactcctc tcttattttt tcaagccaag cttgcttgag tttttctccg accagacgct
    29641 tgccatcagc taggtccaac ttttctagga aacgggcttg gcccagatgg taattggctt
    29701 caaagcctgt aatagcctga tgttgctgga cgtatggggc aatgcttctg ccattttcag
    29761 tataaggatt gatggcgaac cggcctgcta aaatcttctc agcagctttc ttgtaaagat
    29821 aggcattgta gtccagtagg agctgaaatt cctcatctgt cagttgattc gccttgtttt
    29881 tgttataaaa ttcgcctaaa taactgcttt ctttttccaa gaagagccct tggtatttca
    29941 tagatttgct ggcttctacc actgctcctg ccagactttt taccgccatc agagattgga
    30001 caggttcagc catttccaag tacatggcgc cgaaaaagtt ctgctcccct tctcttttta
    30061 gggcagcaag ataggttggt aactgagaat tgagcccatt aaagaaatga ggaaactgga
    30121 actgagtcag actggatttg tagtctacta ctcctatcgc tccattagct ttcaaacggt
    30181 caatccggtc caccttgcct cgtacaaaga cactgcgtcc attgtctaat tgaataaagg
    30241 cttggtcttt tccaccaaaa tttgcttctt ctttgattgt ttcgatggct ggattgtgtc
    30301 ggagaatatg tccagttgtc cgtgcaacat caagcaaaac ttccttggta aactgggctt
    30361 ccaaactttc ttgataaata gcttcaaatt cgcgttcttg actggtttct tgaatagctt
    30421 gttctagacg ttggtcaaag gaatcttcat taggcaactg caaggcgcgt tcaaagatac
    30481 gatgcaagaa attcccgtga ctacgggcat caggacgcaa acgtaattcc tcctgcaagc
    30541 ctaaaacgta gcgtaggaaa taactgtatt cattgcgata aaactctgtc aaacccgacg
    30601 tagacaggta aaactcctgt ttggcaggat agagagcttg caaggtgtcc ttggctaagg
    30661 tcttgctgct tggactgatt gggatggctg gattttccag accttgctga tctagttttt
    30721 tacctatgac acgcgacaga accttgacaa aagtcaaatc ttgctcagta tcgctcatct
    30781 caccctgctg gtgataggca accagactag acaaaagact gtgataggac cccatatcct
    30841 ccttagacag tcctttgtga ttcatcctct tctctctccg cctaaatcca aaatggatca
    30901 actcttgaag ataggcagat tccttacttt cactttcgtt aaaaaggctt ggagccgaca
    30961 agaacaactg cttacgagca gaattgacca aggaaagcat agtgtagcga tttttcttga
    31021 gattttcact gctggcaatc agtaattgaa cgccttcttc ggtcgtttgg tttaggtttt
    31081 gcctttcttc atctgtcaga agactggtgt tttgagaaat ttttggtaaa ttgtcctgag
    31141 ttagtccaat agcatagaca aagtcagcag tcaatggtgc aatcaaatcg taactctgca
    31201 ccagaacagt gtccactgtt gctggaatgg tacggtattg ggacaaactc attccagaat
    31261 ggagcaaggc taggaagtct tccagactaa cctgtgaacc agcaaaaaca gtcgcaaatt
    31321 gttctaaaac atggcagaaa gccttccaaa cttcggcttg tctttcctgt tctacagctt
    31381 ccaaagtggt tgtcaaatct tgtaactgct tggtcacagc tccttctttt agaaagacac
    31441 tccatttttg taggaggttt tcagcctttt gttttcggct ggcaaagagg gtttcaagag
    31501 gtgctaaaat tctcaggcgg aggacattca aacgctcaag attaaatttt ccatggtggg
    31561 atttggtgaa agtttgctga aaggctggca agccattgat accaagatag cggatatatt
    31621 gctcaaaagc atcaatatca gactgactga ggtcagtata caaatcagtt ctaagaagat
    31681 taatcaaatc ctcctgacga aaacggtaac gttttaaagc taaaatagac tcgacaaact
    31741 gagtcaaggg atgatgagcc atggcttcgc ttctaccaag ataaaaagga atctgatact
    31801 ggtcaaaaat ggttttgaga gataactggt aagaagctac atcccccaag agaatacgaa
    31861 aatgcttgta gctcaggtct gagttctcat gtaatttctg acgaatgcta cgggctacta
    31921 gctccaactc ctccttttgc gtcaaacaag accagatttg taaattttca cggtctttct
    31981 catcgacatc caaagcgagt tctgaaaagt cataagaaga ctccaacaaa cgagaggcct
    32041 tgtcaaaact atccatcttc tcatgagttt gagaacagtc ctgagcaggc gtttggtatt
    32101 tagaagccag atgatggaga aattttacgc tggcttggta gagattgccc tcgctaaaag
    32161 gactggtata ggctttctta ctagcataag ccccgataac aatctcaaca cctttgccgt
    32221 gaagtaagtc cacaacccgc tcttcctcag cagaaaaacg agtaaagccg tcaatgacca
    32281 aggtgatttg attaaaatca ctacttacct tgtcattctc aatagcctca atcaaatggg
    32341 acaactgact tccctgggct aactgacctt gattaagata ggctgttact ttctcaaaaa
    32401 tcaagagtaa atccgccctc ttatcctcat ctgttaaatt ctccaagtcc aaaaaactca
    32461 tctgagattt ggtcatctca tggtaaagct caattaactg ctggatcaat tgaggatcct
    32521 gcttaatagc gccataaaca cgcaagtcct tgggatcgag ttcggcaagg catttgtaaa
    32581 aggccaaccc aagaccgata tcatcaagag tagttttaac tggtaaatca ttcaagacca
    32641 gataacgagc catttgagca aagcgcgtga cggtaatcga aaaagaagcc tgctgggaca
    32701 agcattccag cacggcgcgt tccttttcaa aagaaagaga gttgggggca atgtagaaga
    32761 cccgcttgcc agctgcaact agctcttctg cctctcttgt tagaatttct gtcaaagaag
    32821 ttcgaatatc agtataaagt aatttcatct cagcctcgtt ggaatttttc atcaccctat
    32881 attataccat gattagcctc gtaaatctgt taaaatattt aggccatcct ttcttttctt
    32941 catcatctgc taaatcttaa atacttagct ttacttgtat tagatagaat aagtctggct
    33001 actgaaaatc acataataaa aaagcctcgg taacaaggct ttgagtttta tgattgtttc
    33061 ttaggtacgg aatacacttc aatgtgttgt cccagtatct taatgtcgac tggtagattg
    33121 tctgatttat cgccatcaac atcggactct aattcgatat cagaagaagt tttaatatta
    33181 cgtgccttta tatattcaat attcttgata gaatgattga actatagtaa attgaaacta
    33241 taatagtaca ccgtggatgc taaaatattt ctagaaatta atttgatttc cctaatcaag
    33301 ctgttcgtat cttatttcaa tcta
//
LOCUS       DAVBIC010000022        31700 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.022, whole genome shotgun sequence.
ACCESSION   DAVBIC010000022 DAVBIC010000000
VERSION     DAVBIC010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31700)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31700)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31700
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.022"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            complement(1..501)
                     /locus_tag="VQ664_000982"
                     /pseudo
     CDS             complement(1..501)
                     /locus_tag="VQ664_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819352.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
     gene            complement(499..2436)
                     /locus_tag="VQ664_000983"
                     /pseudo
     CDS             complement(499..2436)
                     /locus_tag="VQ664_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399214.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
     gene            3044..3553
                     /locus_tag="VQ664_000984"
     CDS             3044..3553
                     /locus_tag="VQ664_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001088691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HET2789161.1"
                     /translation="MNSRVEFRIFTIVDLDKEEEYLHEMHLKGWRYRTSRFGLFYFDQ
                     CQPDDVIYRIYDSRFLKKYKHELQDFRDRGWELIGAGSCSILRKSSSDLLPEDQVYMS
                     KGLKWEVMRSRLRSCTTTFLGGLVVCTSLFREDLSMSFFLIFVLYAFLISYLIHGYFR
                     LKRKYRVDE"
     gene            3717..4751
                     /gene="hrcA"
                     /locus_tag="VQ664_000985"
     CDS             3717..4751
                     /gene="hrcA"
                     /locus_tag="VQ664_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HET2789162.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFHRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTGLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVNLLNFANLEAYQFFDQPQKVALEIREGLREDQMQNVRVADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQVNVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            4778..5302
                     /gene="grpE"
                     /locus_tag="VQ664_000986"
     CDS             4778..5302
                     /gene="grpE"
                     /locus_tag="VQ664_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HET2789163.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSELDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LGMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            5782..7605
                     /gene="dnaK"
                     /locus_tag="VQ664_000987"
     CDS             5782..7605
                     /gene="dnaK"
                     /locus_tag="VQ664_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HET2789164.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKAKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            7618..7971
                     /locus_tag="VQ664_000988"
     CDS             7618..7971
                     /locus_tag="VQ664_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000115730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789165.1"
                     /translation="MSVNKNNLSDIADYHEKIKFFEELFNLDYNPTEMLVTVERNGNV
                     IYKEFTEVAVGKSKYDHTSVFKDVMIYFSDHICQELHLYKTQDPHYNKFEFDLAKRSL
                     KITTRDNTTIFISNE"
     gene            8176..9312
                     /gene="dnaJ"
                     /locus_tag="VQ664_000989"
     CDS             8176..9312
                     /gene="dnaJ"
                     /locus_tag="VQ664_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HET2789166.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGAGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGRGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFAAAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(9662..9901)
                     /locus_tag="VQ664_000990"
     CDS             complement(9662..9901)
                     /locus_tag="VQ664_000990"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789167.1"
                     /translation="MHHNLGNSYSIKIKKQTRKLGTDCSKHRFKVVDRTDEVSSKHCF
                     EVVDRTDEVSNHTHDKPTLTWFEEIFEEYHSPFHN"
     gene            complement(10063..10350)
                     /locus_tag="VQ664_000991"
     CDS             complement(10063..10350)
                     /locus_tag="VQ664_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789168.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIIDQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
     gene            complement(10360..10770)
                     /locus_tag="VQ664_000992"
     CDS             complement(10360..10770)
                     /locus_tag="VQ664_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HET2789169.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMNATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            10838..11569
                     /locus_tag="VQ664_000993"
     CDS             10838..11569
                     /locus_tag="VQ664_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2789170.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLEQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            11566..12615
                     /locus_tag="VQ664_000994"
     CDS             11566..12615
                     /locus_tag="VQ664_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2789171.1"
                     /translation="MKDLFLKRKQAFRKECLCYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEAIKLHLKRQTG
                     ISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFRQKASKFFTETG
                     LDWDYVISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVPGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSVLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQEVVRGLTSFVLLVELVVGLITFQEKLALLALLGAGLVL
                     LVLYLPYQVKRQMQD"
     gene            complement(12783..13112)
                     /locus_tag="VQ664_000995"
     CDS             complement(12783..13112)
                     /locus_tag="VQ664_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HET2789172.1"
                     /translation="MTDTDPIKRAHTLITDLNKAYQACKQASADDVRFQEQLNSILGF
                     LAKAETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     NENQRAN"
     gene            13389..13727
                     /locus_tag="VQ664_000996"
     CDS             13389..13727
                     /locus_tag="VQ664_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2789173.1"
                     /translation="MKHMIIQTQKTVYKVNVDDIYYIQTHPTKAHTVQIVTEEASFNM
                     LQNLSNLENQYGETLMRCHRNCLVNLDKLKSIDFQERILFLGEEGQYAVKYARRRYRE
                     IRQKWLKEGE"
     gene            13732..14469
                     /locus_tag="VQ664_000997"
     CDS             13732..14469
                     /locus_tag="VQ664_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2789174.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKEHHITPSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRDPYALIVFVTTHSEFMPLSFRYQ
                     VSALDYIDKALSAEEFESRIETALLYANGQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSTRPHRVILYTKTDRLEFTASLEEVLKQEPRLLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINNLH"
     gene            14483..15823
                     /locus_tag="VQ664_000998"
     CDS             14483..15823
                     /locus_tag="VQ664_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET2789175.1"
                     /translation="MNVAWILLYTLVTHGLKIVIFFKVDGISLTFERIFKAFLFKILL
                     AVVFGMLGYMVGNTYLSYFMEPLYGIGLSFLLLRELPKKLLLFYGLFPMILVNLFYRG
                     VSYFVLPFLGQGQVYDDYSFIWLCIIIFNFFISLAFLKWLDYDFTSLRKGILDKDFQK
                     SLTQINWIMGAYYLVIQNLSYFEYEQGIQSTTVRHLILVFYLLFFMGIIKKLDTYLKD
                     KLHERLNQEQDLRYREMERYSRHIEELYKEVRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EIYDSVLKDSSEKLQDNKYDLGRLVNIRDKALKSLLAGKFLKARDKNIVFNVEVPEEI
                     QVEGMSLLDFLTVVSILCDNAIEASVEACQPHVSIAFLKNGAQETFIIENSIKEEGID
                     ISEIFSFGASSKGEERGVGLYTVMKIVESHPNTSLNTTCQDHVFRQVLTVIHIE"
     gene            complement(15867..16022)
                     /gene="blpC"
                     /locus_tag="VQ664_000999"
     CDS             complement(15867..16022)
                     /gene="blpC"
                     /locus_tag="VQ664_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HET2789176.1"
                     /translation="MDKKQNLTSFQELTTTELNQIIGGGWWEDFLYRFNIIEQKNTKG
                     FHQPIQL"
     gene            complement(16079..17440)
                     /locus_tag="VQ664_001000"
     CDS             complement(16079..17440)
                     /locus_tag="VQ664_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HET2789177.1"
                     /translation="MNPNLFRSVEFYQRRYHNYATVLIIPLSLLFTFILIFSLVATKE
                     ITVTSQGEIAPTSVIASIQSTSDNPILANHLVANQVVEKGDLLIKYSETMDESQKTAL
                     ETQLQRLEKQKEGLGILKQSLEKATDLFSGEDEFGYHNTFMNFTKQSHDIELGITKTN
                     TEVSNQANLANSSSSAIEQEITKVQQQIGEYQELRDAIINNRARLPTGNPHQSILNRY
                     LIASQGQTQGTAEEPFLSQINQSIASLESSIASLKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLENNTLTAPSKGIVHLNSEFEGKNRI
                     PTGTEIAQIFPVITDTREVLITYYVSSDYLLLLDKGQTVRLKLEKIGNHGTTIIGQLQ
                     SIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTTKKTYFDYFKDKILT
                     HSD"
     gene            complement(17451..19040)
                     /locus_tag="VQ664_001001"
                     /pseudo
     CDS             complement(17451..19040)
                     /locus_tag="VQ664_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864064.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
     gene            complement(19033..19620)
                     /locus_tag="VQ664_001002"
     CDS             complement(19033..19620)
                     /locus_tag="VQ664_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C39"
                     /protein_id="HET2789178.1"
                     /translation="MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKT
                     NKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDVPYPFIVHVNKEGKLQHYYVVYQ
                     TKKDYLIIGDPDPSVKITKMSKERFFYEWTGVAIFLATKPSYQPHKDKKNGLLSKLPS
                     SDFQTKISHCLHCSLKLIGHYYQYRWFLLSPRNLG"
     gene            19902..20099
                     /gene="blpI"
                     /locus_tag="VQ664_001003"
     CDS             19902..20099
                     /gene="blpI"
                     /locus_tag="VQ664_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpI"
                     /protein_id="HET2789179.1"
                     /translation="MNTKMMEQFSVMDNEELEIVSGGRGNLGSAIGGCIGAVLLAAAT
                     GPITGGAATLICVGSGIMSSL"
     gene            20566..20835
                     /gene="blpJ"
                     /locus_tag="VQ664_001004"
     CDS             20566..20835
                     /gene="blpJ"
                     /locus_tag="VQ664_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpJ"
                     /protein_id="HET2789180.1"
                     /translation="MNTKMLSQLEVMDTEMLAKVEGGYSSTDCQNALITGVTTGIITG
                     GTGAGLATLGVAGLAGAFVGAHIGAIGGGLTCLGGMVGDKLGLSW"
     gene            20904..21134
                     /gene="blpU"
                     /locus_tag="VQ664_001005"
     CDS             20904..21134
                     /gene="blpU"
                     /locus_tag="VQ664_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HET2789181.1"
                     /translation="MDTKMMSQFSVMDTEMLACVEGGGCNWGDFAKAGVGGAAARGLQ
                     LGIKTGTWQGAATGAAGGAILGGVAYAATCWW"
     gene            21137..21256
                     /locus_tag="VQ664_001006"
     CDS             21137..21256
                     /locus_tag="VQ664_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HET2789182.1"
                     /translation="MDFKSFIIGLVVGIFGPYMYNLIRKIFSKFPKKDTDSTP"
     gene            21555..21719
                     /locus_tag="VQ664_001007"
     CDS             21555..21719
                     /locus_tag="VQ664_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789183.1"
                     /translation="MKKKILIIFVLYLIMSIFLYPLRESAWYQLFYTIAYVIAVMIYF
                     AINKKKGEKK"
     gene            21716..22102
                     /locus_tag="VQ664_001008"
     CDS             21716..22102
                     /locus_tag="VQ664_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HET2789184.1"
                     /translation="MKTFFAKKRNIFLARLFLGQLPLLVSTYLFLSRQFLNFSVVFQF
                     LLVVINLASILVTVYLTREMRIREFEDDDLVSPRTNQLMFIGLADFMFVICLYRGISE
                     TEFYQQLIAYIGVFSACLSRFCSCGA"
     gene            22202..22600
                     /locus_tag="VQ664_001009"
     CDS             22202..22600
                     /locus_tag="VQ664_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HET2789185.1"
                     /translation="MKYRLFFVIFLSSVLDILLGTFLQISIVSIGWLVLYSGLFEVGV
                     FLLANKGVAVKIKEVDIRNRFKFIFGKTLWFQILLLIFLIIKLYLGLDARLILFYGHI
                     FIVFNALMYLLSSSQVSLKKKQTVFLILQQ"
     gene            22638..23327
                     /locus_tag="VQ664_001010"
     CDS             22638..23327
                     /locus_tag="VQ664_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2789186.1"
                     /translation="MKKYQLLFKISAVFSYLFFVFGLSQLTLIVQNYWQFSSQIGNFV
                     WIQNILSLLFIGVMIVVLVKTGHGYLFRIPRKKWLWYSILTVLVVVFQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYIALFFLVPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFSSLPSLLDIFVFATVGIIFAGLTRYTKSIYPSYAVHVINNIVATFP
                     FLLTFLHRVLG"
     gene            23369..23617
                     /locus_tag="VQ664_001011"
     CDS             23369..23617
                     /locus_tag="VQ664_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789187.1"
                     /translation="MYKHLFFLDSKTLDRLTPYILVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFIGAGYVVGFWLLKWFVLERLELKDDA"
     gene            23647..24258
                     /locus_tag="VQ664_001012"
     CDS             23647..24258
                     /locus_tag="VQ664_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2789188.1"
                     /translation="MEFFDKFHALCFGFLVLIIVITVPYTINHGGFFQNESALILVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGFAYKKSQNLWVSTLVHMFYNSWPLLYYL"
     gene            24419..25213
                     /locus_tag="VQ664_001013"
     CDS             24419..25213
                     /locus_tag="VQ664_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HET2789189.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            25210..25845
                     /gene="trmB"
                     /locus_tag="VQ664_001014"
     CDS             25210..25845
                     /gene="trmB"
                     /locus_tag="VQ664_001014"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HET2789190.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEVGVPNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            25971..26450
                     /gene="rimP"
                     /locus_tag="VQ664_001015"
     CDS             25971..26450
                     /gene="rimP"
                     /locus_tag="VQ664_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HET2789191.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEIISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTRKKTVQIPYSLVSKARLAVKL"
     gene            26494..27630
                     /gene="nusA"
                     /locus_tag="VQ664_001016"
     CDS             26494..27630
                     /gene="nusA"
                     /locus_tag="VQ664_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HET2789192.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            27652..27945
                     /locus_tag="VQ664_001017"
     CDS             27652..27945
                     /locus_tag="VQ664_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HET2789193.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            27938..28237
                     /locus_tag="VQ664_001018"
     CDS             27938..28237
                     /locus_tag="VQ664_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HET2789194.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLTKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            28254..31046
                     /gene="infB"
                     /locus_tag="VQ664_001019"
     CDS             28254..31046
                     /gene="infB"
                     /locus_tag="VQ664_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HET2789195.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKAEKSEPAKPAVAKEEAKPAEPVAPKTEKVA
                     VKPQSRNFKAEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNR
                     RFNDQAKKQQGQQKRRNERRQQEDKRSNQAAPRIDFKARAAALKAEQNAEYARSSEER
                     FKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKK
                     QARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTP
                     KPVTERKFHELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGET
                     IELLMVDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTL
                     LDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDIT
                     ILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTA
                     WGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAV
                     ATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGD
                     HFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADV
                     QGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQAR
                     QQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIG
                     GFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDGYNDI
                     KMDDVIEAYVMEEIKR"
     gene            31297..31647
                     /gene="rbfA"
                     /locus_tag="VQ664_001020"
     CDS             31297..31647
                     /gene="rbfA"
                     /locus_tag="VQ664_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HET2789196.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
BASE COUNT         9481 a         5730 c         6793 g         9696 t
ORIGIN      
        1 gataagaata gaagcaactt tatcactatt caagtttttc acaacagctc cactaattag
       61 agatagaaat tgagaataaa ctacatttga tgaaagaata tagaataggt aatctttatt
      121 taatgagttt tcatagttcg aaatagccaa ccatccatcg tgtattgcac catcaacatt
      181 caaaatataa ggtctaccaa aactcataga attagttaac aaaaatgtac ctttttttac
      241 aaatctagtt ttgttaagcc ctgatttttt gattttttct ttaacattat ttatatactt
      301 ttcacccttt tcagtatcac ctatttttat ccaatttatt ccatctactt cagaagtaag
      361 ataatctttg attggtcgtg gagagccacc tctgacaatt tcaaccaatg tagaaaacct
      421 cacccactcc caagtatcag gaatatcata aggaacatca atttcttgag tgcttccatc
      481 agcaaacttc ccataatgtt tcttatctgc cgtatgccaa actgtgataa aatcgttcaa
      541 agtggcgtag ctacctaaga tattctttcg agtgtagtcg gtcaggcttt cggtaatcag
      601 tttcccgttt tcatccaata cttgaacagt agaattaaga atggtaacct gcttgtctgt
      661 aacgatatat ttttctactg ggtcaccttc ctcacctacg aaaccaggcg tagaaccact
      721 gactgttttc gcacctgttt ccagcacctt cactggctca ccatcaaaat cagggtcagc
      781 aaacaaattg gtaacatttc gaaaatcaat aatcgtaaaa aattctttcc ccttttgagg
      841 ataaagacgt gtgccacgac caataatttg tttaaattca gtcatggatt ggatattaga
      901 gtctaaaaca atcaaacgac atgttttagc attaactcct gtcgttaata atttagacgt
      961 tgttacaata gcgggaaaat tagaattgac atccataaag ttatccagtt gagcttttcc
     1021 ttcagcgttg tcaccagtta cttgcatgac ataacgatag tcttcttgga ctaagtctag
     1081 attctctttt acaagtgcag cacgcattcg ctcggcatgg tcaatatcaa cacaaaaaac
     1141 aattgtttta tcaaatcgtg cattgttttg cttcatataa tcagaaacaa acttggcaac
     1201 tctttgcgtt ctatcatcaa tgacaatggt tttatcaaaa tctttcctgc cgtagtacct
     1261 atcttctatt aattgtccgt tagcatcaac ttttccagtt tctggacgat aaccatccac
     1321 atccacatct aaattaaccc tcataacacg atatggagcc aaaaaaccat cctcgattcc
     1381 ctgttttaaa ctataagtat agattggctt accaaagtat tccgtattgg aagcattctt
     1441 ggtttcttta ggagtagcgg tcatcccaat ctgtgtcgca gaactgaaat aatcaattac
     1501 cttacgccag ttactgtttt ccttagctga accacggtgc gcttcatcaa ttacgattaa
     1561 atcaaagaag tctttgtcaa atttttgata atgtgtttca gttccatctt caccagttag
     1621 ttgctgataa agccctagat aaatttcgaa agaatttaat ttttcaggag cagtcaaaag
     1681 ttttggtgta attttcgtca ttaccttttc gaatggctta aagtcttcag ccatcgtttg
     1741 gtctactaag atgtttctat ctgctaagaa taaaactcgt ttagccaaac cagcttttcg
     1801 aaggcgatga ataatttgaa aagccatgaa cgttttccct gttcctgttg ccatcacaaa
     1861 cattactcgt ttttgtcctc tggcaactgt ttcaatagta cggttgatag ctatttgctg
     1921 ataatagcgt ggcgttttca ttgagaaggc gtctgtatag tatggagttg agatagcttc
     1981 tgtaatttcg tacgtcaatc ctttttcctt cgtcatacga gaaaataatt cttcacgagt
     2041 agggaattcg tctaactcca gctcacgttc ttctctcgtg atacggtcgt gttcaataaa
     2101 gccatcacca ttcgaagaat aaacaaatgg aacatctaaa atctctccat attcaatagc
     2161 ttgttgtaat cctgctcgaa cgctgtgttt attatccttt gcctcaacaa ttgcaattcg
     2221 agttccaaat tggtaataca gtgaatagtc tgattttttt ccttctttac gacgagcctt
     2281 atctcctcta acctcaattc gaccatcagt gaagtattct tcgtaagcga tatgctcacc
     2341 atttttccat cctttggata caatagcagg agtgatgaaa tttgctttaa tatcctcctc
     2401 actcatttct ttcttagact ttataaactc aaccatattg aaccctccgc attctaaaaa
     2461 tctacttctc cataaaataa actatcagaa caaattatac ttctattata tcacacttat
     2521 aaaaatactc tgctaaattg ttgaaaataa gtatgcaata tactttcgca tcgcgtcaga
     2581 ttatctccgc ataacaccgc tattttccgc tgttttcggc aggcgactta ttatcattct
     2641 ataagcactt tcagtcgggc tggtgagcta tttttcaaaa ataaataatc acatttaaac
     2701 attttgaaag tataaaatat ctacatcagc cgttcaaaaa ctggcgtaaa ttttgctata
     2761 atattttagt ttaaataaag atttttttat gccaaacgga ttttaacaat gcggatgctt
     2821 cctattttac ttctcttttt agctctacta ccgttttgct caaagtttgt cactggaggt
     2881 agttctttca gttggaaagt gtttttgatt ttcataatag attgggtttt attgatagtt
     2941 tttgcgattc agatttctta tattttttgg agattgagtc aaaagtggaa agaattatct
     3001 aataaataac gccaggcatg ttttctaatt ttggggtaag acaatgaata gcagagtaga
     3061 atttcggatt ttcaccattg ttgatttgga caaggaagaa gaatatttac atgagatgca
     3121 tttgaaaggt tggaggtata gaacgagtcg ttttggtttg ttctattttg accaatgtca
     3181 accagacgat gtcatctacc gtatctatga ttctagattt cttaaaaaat ataagcatga
     3241 actgcaagat tttagagata gaggttggga attgatagga gcaggttctt gttcgattct
     3301 tcgtaaatcg tcttctgatt tacttccaga ggatcaagtc tatatgagta aggggctcaa
     3361 atgggaagtt atgcgatcta gacttcgttc ctgtacaact actttcttag gtggtcttgt
     3421 tgtttgtacg agtttgttta gagaggatct ttctatgtct ttctttctta tttttgtttt
     3481 atatgctttt ctgatttctt atctaattca tggttatttc agactaaaaa ggaaataccg
     3541 agtagatgaa tagcaaggtt ctaggtcttc agattgattt ttagcactct tgataaaaga
     3601 gtgctaattt tttgagtttt tgtcttgaca ttctctttta agggtgtata atagaatcat
     3661 aagttagcac ttggatgcat tgagtgctaa ttgatcagac agagaggagt gatgagatgg
     3721 ttacagagcg tcagcaggat attttaaatc tgattattga catctttacc aaaacgcacg
     3781 aacctgtcgg atcaaaagcc ttgcaagagt ctattaactc tagcagtgca accattcgta
     3841 atgacatggc ggaactagaa aaacaagggt tgcttgagaa ggctcatact tcaagcggtc
     3901 ggatgccaag tgttgctggt tttcagtact atgtgaaaca ctcactggat tttcaccggc
     3961 tggctgaaaa tgaggtatat gagattgtca aagcctttga tcaggaattc ttcaaattgg
     4021 aggatattct gcaagaggct gctaacttgc taacaggcct gagtggctgt acggtagtgg
     4081 cactggatgt tgagccgagc aggcaacgtt tgacagcctt tgatatcgtt gttttggggc
     4141 aacatacagc cttggcggta tttaccctag acgagtcgcg aacggttact agtcagtttc
     4201 tgattccaag gaacttcttg caggaggatt tgctgaaact gaagagcatc attcaggaac
     4261 gtttcctcgg tcacaccgtt ttagatattc actacaagat tcggacggag attccgcaga
     4321 ttatccagcg ttactttaca acaacggata atgtcatcga tctctttgaa cacatcttta
     4381 aggaaatgtt caacgaaaac attgtgatgg cgggcaaggt caatctcttg aattttgcca
     4441 atctagaagc ctatcagttc tttgaccaac cgcaaaaggt ggccttggag attcgtgagg
     4501 ggttgcgtga ggatcagatg caaaatgttc gtgttgcaga cggtcaagag tcctgtttag
     4561 ctgacctagc ggtgattagt agtaagttcc tcattcctta tcggggagtt ggaattctag
     4621 ccattatcgg tccagttaat ctggattacc aacagctaat caatcaagtc aatgtggtca
     4681 accgtgtttt gaccatgaag ttgacagatt tttaccgcta cctcagcagt aatcattacg
     4741 aagtacatta agattgaaat cattaaagga ggcgaacatg gcccaagata taaaaaatga
     4801 agaagtagaa gaagttcaag aagaggaagt tgtggaaaca gctgaagaaa caactcctga
     4861 aaagtctgag ttggacttgg caaatgaacg tgcagatgag ttcgaaaaca aatatcttcg
     4921 cgctcatgca gaaatgcaaa atatccaacg ccgtgccaat gaagaacgtc aaaacttgca
     4981 acgttatcgt agccaggact tggcaaaagc aatcttacca tctcttgaca accttgagcg
     5041 tgcacttgca gttgaaggtt tgacagatga tgtgaagaag ggcttgggga tggtgcaaga
     5101 aagcttgatt cacgctttga aagaagaagg aattgaagaa atcgcagcag atggcgaatt
     5161 tgaccataac taccatatgg ccatccaaac tctcccagca gacgatgaac acccagtaga
     5221 taccatcgcc caagtctttc aaaaaggcta caaactccat gaccgcatcc tacgcccagc
     5281 aatggtagtg gtgtataact aagatacaaa gctcgtaaaa agctcgcagt aaaaatagga
     5341 gattgacgaa gtgttcgatg aacacaagaa aatctatctt ttttactcag agcttagggc
     5401 gtgttcgatt cggcaattct gacggtagct aaagcaactc gtcagaaaac ggcaatcgct
     5461 atgacgtttg cctagcttcc ttactaactc gtcgtcgaaa taaaatcgat ttcgactcct
     5521 cgtgtcgcaa tttacataat agaaaacttg tccgaaacga caataaacta tgaagaaaga
     5581 taaaatatgt ttggctttgt aatagtgagc gaagcgaacc aaagacgata ctcttcgccg
     5641 tggtgctatt tgcgcaaatt ttgagacctt aggctcaaag tttagtcaaa gagattgacg
     5701 aagtcaagct ctgacggcgt cgccacttaa gaagagtatc aaaaagaaaa atagaaaatt
     5761 aactaacaag gagaaaaaca catgtctaaa attatcggta ttgacttagg tacaacaaac
     5821 tcagcagttg cagttcttga aggaactgaa agcaaaatca tcgcaaaccc agaaggaaac
     5881 cgcacaactc catctgtagt ctcattcaaa aacggagaaa tcatcgttgg tgatgctgca
     5941 aaacgtcaag cagttacaaa cccagataca gttatctcta tcaaatctaa gatgggaact
     6001 tctgaaaaag tttctgcaaa tggaaaagaa tacactccac aagaaatctc agctatgatc
     6061 cttcaatact tgaaaggcta cgctgaagac taccttggtg agaaagtaac caaagctgtt
     6121 atcacagttc cggcttactt caacgacgct caacgtcaag caacaaaaga cgctggtaaa
     6181 attgctggtc ttgaagtaga acgtattgtt aacgaaccaa ctgcagcagc tcttgcttat
     6241 ggtttggaca agactgacaa agaagaaaaa atcttggtat ttgaccttgg tggtggtaca
     6301 ttcgacgtct ctatccttga attgggtgac ggtgtcttcg acgtattgtc aactgcaggg
     6361 gacaacaaac ttggtggtga cgactttgac caaaaaatca ttgaccactt ggtagcagaa
     6421 ttcaagaaag aaaacggtat cgacttgtct actgacaaga tggcaatgca acgtttgaaa
     6481 gatgcggctg aaaaagcgaa gaaagacctt tctggtgtaa cttcaacaca aatcagcttg
     6541 ccatttatca ctgcaggtga ggctggacct cttcacttgg aaatgacttt gactcgtgcg
     6601 aaatttgacg atttgactcg tgaccttgtt gaacgtacaa aagttccagt tcgtcaagcc
     6661 ctttcagatg caggtttgag cttgtcagaa atcgacgaag ttatccttgt tggtggttca
     6721 actcgtatcc ctgccgttgt tgaagctgtt aaagctgaaa ctggtaaaga accaaacaaa
     6781 tcagtaaacc ctgatgaagt agttgctatg ggtgcggcta tccaaggtgg tgtgattact
     6841 ggtgatgtca aggacgttgt ccttcttgat gtaacgccat tgtcacttgg tatcgaaaca
     6901 atgggtggag tatttacaaa acttatcgat cgcaacacta caatcccaac atctaaatca
     6961 caagtcttct caacagcagc agacaaccaa ccagccgttg atatccacgt tcttcaaggt
     7021 gaacgcccaa tggcagcaga taacaagact cttggacgct tccaattgac tgatatccca
     7081 gctgcacctc gtggaattcc tcaaatcgaa gtaacatttg acatcgacaa gaacggtatc
     7141 gtgtctgtta aggccaaaga ccttggaact caaaaagaac aaactattgt catccaatcg
     7201 aactcaggtt tgactgacga agaaatcgac cgcatgatga aagatgcaga agcaaacgct
     7261 gaagccgata agaaacgtaa agaagaagta gaccttcgta atgaagtaga ccaagcaatc
     7321 tttgcgactg aaaagacaat caaggaaact gaaggtaaag gcttcgacgc agaacgtgac
     7381 gctgcccaag ctgcccttga tgaccttaag aaagctcaag aagacaacaa cttggacgac
     7441 atgaaagcaa aacttgaagc attgaacgaa aaagctcaag gacttgctgt taaactctac
     7501 gaacaagctg cagcagcgca acaagctcaa gaaggagcag aaggcgcaca agcaacagga
     7561 aacgcaggcg atgacgtcgt agacggagag tttactgaaa aataaggggc tagtgttatg
     7621 agtgttaata aaaataatct ttctgacatt gcagattatc atgaaaagat aaagtttttt
     7681 gaagaattat ttaatttgga ttataatcca acagaaatgc tggtgactgt ggaaagaaat
     7741 ggaaatgtca tttataaaga atttacagaa gtagctgttg gtaagagtaa atatgaccac
     7801 acttctgtgt ttaaagatgt tatgatttac ttttcggatc atatatgtca ggagttacac
     7861 ctatataaaa cacaagaccc acactataat aaatttgagt ttgatttagc taaaaggtct
     7921 ttgaagatta ctactagaga taatacaacc atttttattt caaatgaata atctaaccac
     7981 agaggttgca actcagcctc tgtttttcgg taaaaaggga tagggccgag tggctggagt
     8041 attatctcat caatataaaa gaaaggaatt gaacccgacc taaattctcg gaaaaaagag
     8101 aaatctgtct aggagcgtcg ctccagcgtc agatttccta tttttcagtc gaattttacg
     8161 gtcttggtat cttgtatgaa caatactgaa ttttatgatc gtctgggggt gtcaaaaaac
     8221 gcttcggcag acgagatcaa aaaggcttat cgtaagcttt ccaaaaaata tcacccagat
     8281 atcaacaagg agcctggtgc tgaggacaag tacaaggaag ttcaagaagc ctatgagact
     8341 ttgagtgacg accaaaaacg tgctgcctat gaccagtatg gtgctgcagg cgccaatggt
     8401 ggttttggtg gagctggtgg tttcggtggt ttcaatgggg caggtggctt cggtggtttt
     8461 gaggatattt tttcaagttt cttcggcgga ggcggttctt cgcgcaatcc aaacgctcct
     8521 cgccaaggag atgatctcca gtatcgtgtc aatttgacct ttgaagaagc tatcttcgga
     8581 actgagaagg aagttaagta tcatcgtgaa gctggctgtc gtacatgtaa tggctctggt
     8641 gctaagccag ggacaagtcc agtcacttgt ggacgctgtc atggcgctgg tgtcattaac
     8701 gtcgatacgc agactcctct tggtatgatg cgtcgccaag taacctgtga tgtctgtcac
     8761 ggtcgaggaa aagaaatcaa atatccatgt acaacctgtc atggaacagg tcatgagaaa
     8821 caagctcata gcgtacatgt gaaaatccct gctggtgtgg aaacaggtca acaaattcgc
     8881 ctcgctggtc aaggcgaagc aggctttaac ggtggacctt atggggactt gtatgtagta
     8941 gtttctgtag aagctagcga caagtttgaa cgtgaaggaa cgactatctt ctacaatctc
     9001 aacctcaact ttgtccaagc ggctcttggt gatacagtag atattccaac tgttcacggt
     9061 gatgttgaat tggttattcc agagggaact cagactggta agaaattccg cctacgtagt
     9121 aagggggcac cgagccttcg tggcggtgca gttggtgacc aatacgttac tgttaatgtc
     9181 gtaacaccga caggcttgaa cgaccgccaa aaagtagcct tgaaagaatt cgcggctgct
     9241 ggtgacttga aagtaaatcc aaagaaaaaa ggcttctttg accatattaa agatgccttt
     9301 gatggagaat aatactcttt gaaaatctct tcaaaccacg tcagcgtcga aaatctcttc
     9361 aaaccacgtc agcgtcggct tgccgtatat atgtgagtcg tatctacaac ctcaaaacag
     9421 tgttttgagc agcccgtggc tagtttccta gtttgctttt tgattttcat tgagtataaa
     9481 caaaaagagc tgtcgggctc tttttacttt atagattttt taagactttc ctaagtaatg
     9541 acggacggta gcgacctcct tcgaagttcc atacctaaac tttgaaccta agtcttaaag
     9601 tttccggaca gctgaaacca agctgtttca ggtgttttca ttacggcaga aagtcttcga
     9661 tttagttgtg aaatggtgaa tgatactctt caaaaatttc ttcaaaccac gtcagcgtcg
     9721 gcttgtcatg ggtatggtta ctgacttcgt cagttctatc cacaacctca aaacagtgtt
     9781 ttgagctgac ttcgtcagtt ctatccacaa ccttaaaacg gtgttttgag cagtctgtgc
     9841 ctagctttct agtttgcttt ttgattttta ttgagtatga gttacctaaa ttatgatgca
     9901 tagttgatgg gatatatata gtagattgaa atagaatatg aacaaattga taagaggatt
     9961 ttaaagtaat ctctaacaat gctttagaaa ctatgatgtg ctattctaaa ttcaattcac
    10021 tataacttgt ttacgtttta aaaaagagcc ggggggctct ttttacttat cttcagttcc
    10081 ctgcatttct tttatcacag ctagtctagt ctggatatcc ttttccaaga ccttaaactt
    10141 gtaagtcaag tcttcttggt attccttgat aagttctttt tgctggtcga tgatttgcag
    10201 gctattttgg ataatatcca catcgtcttt gatagcttga acgcggtcag tggtattcaa
    10261 gacttcatct gtgatggttt ggcgattttt tgtaaccaga taacttccgg ctgcagctcc
    10321 tgcaaatagc agtaggttgg ataatttcat agcaactcct taagcgtttt tgatggtttc
    10381 agcgacttga gcaagtttgt caaagtctgg ttcgtgggcg ataaaatcaa tcttgaggtc
    10441 atcgtcagca ctgtagcgag gcacaaggtg aacgtgagta tgaaaaactg tttgaccagc
    10501 gacttcttca cagttggaaa tgatattcat accagcagcc ttagtgactt tcatgacttt
    10561 ttgagctact tttggtactt gggcaaagag ttggctggcg ctcgtagcat tcatctccaa
    10621 aagattgcga tagtgttctt ttggcacgac caaggtgtgt cctagtgtta cttgagagat
    10681 atcaagaaag gcaaggacct gctcatcttc atatactttt gaagcaggaa tttcccctgc
    10741 gatgatttta caaaaaatgc aatctgacat aaaatctacc tctactgtac tgaattttga
    10801 tataatatag ctacattata ccagatttgg agaaaatatg ttagaaatta aaaacctgac
    10861 aggtggctat gttcatgttc ctgttttgaa agatgtgtcc tttactgttg aaagtgggca
    10921 gttggtcggt ttgattggtc tcaatggtgc tgggaaatca acgacgatca atgagattat
    10981 cggtctgttg gcaccttata gtggctccat caatatcaat ggcctgactc tgcaaggaga
    11041 tgcgactagc taccgcaagc agattggcta cattcctgag acgcctagtc tgtatgagga
    11101 attgaccctc agagagcata tcgaaacggt tgctatggct tacggtattg agcaaaaagt
    11161 ggctttcgaa cgagtagagc ccttgttaaa aatgttccgt ttggaacaga aattagactg
    11221 gttccctgtt catttttcaa aagggatgaa gcagaaggtc atgattatct gtgcttttgt
    11281 ggtggatcca agtcttttca tcgtggatga gcctttcctt ggtcttgatc cgctggctat
    11341 ttctgatttg attcagcttt tggaagtgga gaagcaaaag ggcaagtcta ttctcatgag
    11401 tacccacgtg ctggattcgg cggaaaagat gtgtgatgcc tttgtcattc ttcacaaggg
    11461 agaggtgcgt gccaaaggca atctcctgca actacgtgaa gcctttgata tgcctgaggc
    11521 tagtttgaat gatatttact tggctctgac caaagaggag gatctatgaa agacttgttt
    11581 ttaaagagaa agcaggcctt tcgtaaggag tgtctttgtt atctgcgcta tgtgctcaat
    11641 gaccactttg tcttgttcct gcttgtcctg ttgggctttc tagcctacca gtacagtcaa
    11701 ctcttacaac attttcctga aaatcattgg cctatccttt tgtttgtagg aattacgtct
    11761 gttttactct tactttgggg aggaattgcc acctatatgg aggctccaga caagctcttt
    11821 ctcttagttg gagaagaggc aatcaagctc catctcaagc gtcaaactgg catttcccta
    11881 gtcttttggc tctttgtaca gacccttttc ttgctgttat ttgcgccttt atttttagca
    11941 atgggttatg gcttgccagt ttttctgcta tatgtgcttt tattgggggt aggaaaatat
    12001 ttccactttc gtcaaaaggc cagcaaattt tttactgaaa ctggactgga ctgggactat
    12061 gttatttctc aagaaagcaa gcgtaagcaa gtcttgcttc gtttctttgc cctctttacg
    12121 caggtcaagg gaatttcaaa cagcgttaag cgtcgtgcct atctggactt tatcttaaag
    12181 gctgttcaga aggtgcctgg gaagatttgg caaaatctct atctgcgttc ttatctgcga
    12241 aatggcgacc tctttgctct cagtcttcgt cttctattac tttccgtact ggcgcaggtt
    12301 tttatcgagc aagcttggat tgcgacagca gtggtagttc tctttaacta cctcttgctc
    12361 ttccagttgc tggccctcta tcatgccttt gactaccagt atttgaccca actctttccg
    12421 ctggacaagg ggcaaaagga aaaaggctta caggaggtag ttcgaggatt gaccagtttt
    12481 gttttacttg tggaattagt tgttgggttg attaccttcc aagaaaaact ggcccttcta
    12541 gccttactag gagctggttt ggttttacta gtcttgtatt tgccttatca ggtaaaacgt
    12601 cagatgcagg actaacattg ctgatacgac actaaaaaag aagttgagtt cagtctgtct
    12661 cagcttcttt tttgttacta caggataatg gttggtccgt agagacttat actcttcgaa
    12721 aatctcttca aaccacgtca gcgtcgcctt accgtactca agtacagctt gcggctagct
    12781 tcctagtttg ctctttgatt ttcattgagt attaacttgg tcttgacttg gtcaaagtgg
    12841 aagcggtcat aggcccgcca agcggcgcga gttggagcat ctggatcaag agcgctgagt
    12901 cccatgagaa gactggaagt ctggtaaaat ttttctagtt caatcaagaa tcgattatcc
    12961 actgtttcag ccttggctaa aaaaccaaga atagagttta attgctcctg aaagcggacg
    13021 tcgtcagcgc ttgcctgttt gcatgcttgg taggctttgt ttaagtcagt aatcaaagta
    13081 tgagctcttt tgatggggtc tgtatctgtc atgggaatgc ctcctttaat ctgggtgcca
    13141 gtcttacttc tggcaactgt gttttgatac tgttagttta tcatttttaa ttcttttttt
    13201 ttattcaaat ctttaattgt cattgaaatg tcttgaattg cgctgagtga attttatgat
    13261 aaaatagttg taagctcatc atgatgttgt agaaaaataa tccttttagg agctttcaaa
    13321 gactgtttag gattgggtgg gcttgggcta gaacttttct gttattcttt tcttaggagg
    13381 agaatccaat gaaacatatg attattcaga cgcagaaaac agtctataaa gtaaacgtcg
    13441 acgatatcta ctatatccaa acacatccaa ctaaagccca taccgtacag attgttacag
    13501 aagaagctag ttttaatatg cttcaaaatt taagtaatct tgagaaccaa tatggggaaa
    13561 ccttgatgag atgtcatcga aattgtttgg ttaatcttga taaattaaaa tcgattgatt
    13621 ttcaagaaag aatccttttt ctcggagaag aaggtcaata cgctgtcaag tatgccagac
    13681 gtcgctatag agaaattcgt caaaaatggt tgaaagaggg agagtaagaa gatgagaata
    13741 tttgttttag aggatgattt ttcccaacag actaggattg aaacgacgat tgagaaactc
    13801 ttgaaggaac atcatatcac tcccagctct tttgaggtat ttggcaagcc agaccaactg
    13861 ctggcagagg tgcatgagaa gggggcccat cagctattct ttttggatat tgagattcga
    13921 aatgaggaga tgaagggtct ggaagtggct agaaagattc gggatcggga tccgtatgcc
    13981 ctgattgtct ttgtgacgac tcactcggag tttatgcccc tgtcctttcg ctaccaagtg
    14041 tctgctctgg actatattga taaggccctt tcggcagagg agtttgaatc tcgtatcgag
    14101 acagccctcc tctatgccaa tggtcaagac agtaaaagtc tagcggaaga ttgcttttac
    14161 tttaaatcaa aatttgctca attccagtat ccttttaaag aggtttacta tctcgaaacg
    14221 tccacaagac cccatcgtgt tattctctat accaagacag acaggctgga atttacagcg
    14281 agtctagagg aggttctcaa gcaggagcct cgtctcttgc agtgccatcg ctcttttctc
    14341 atcaatcctg ccaatgtggt gcatttagat aagaaagaaa aactgctttt ctttcccaat
    14401 ggtggaagtt gtctaatcgc gcgttataag gtcagggaag tgtctgaggc tattaataac
    14461 ttacactgag ctaggagagt ttatgaatgt tgcttggata ttgttgtata cacttgttac
    14521 tcacggatta aaaattgtca tattctttaa ggtagatgga attagtctca cttttgagag
    14581 gatttttaag gcctttcttt ttaagatact gttggccgtt gtttttggaa tgcttggcta
    14641 tatggtagga aatacttatc tatcttattt tatggaaccc ttgtacggca taggcttatc
    14701 tttcttattg ttaagagaac ttcctaaaaa actccttctc ttttatggtc tctttccaat
    14761 gatattagtg aatctctttt atagaggtgt ttcctatttt gtgcttccat ttttgggaca
    14821 agggcaagta tatgatgact actcatttat ttggttatgt ataataattt tcaatttctt
    14881 catttctcta gcttttttga aatggttgga ctatgatttc actagcttga gaaaggggat
    14941 tctcgataaa gattttcaaa agtccctgac tcagattaac tggataatgg gggcttacta
    15001 tttggtgata caaaatctgt cttactttga atatgaacag gggattcaat caacgactgt
    15061 tcgccatctc atcctagtct tttacctgct cttttttatg gggattatca agaaattgga
    15121 tacctatttg aaggacaaac tccatgagag actgaaccaa gagcaggact tgcgctacag
    15181 agagatggag cggtatagtc ggcatataga ggagctttat aaggaagtac ggagttttcg
    15241 ccatgactac accaacctct tgactagctt acgtctgggc attgaagagg aggatatgga
    15301 gcagataaaa gagatctacg actcggtctt aaaggattct agtgaaaaat tgcaggacaa
    15361 taaatatgac cttggtcgat tggtgaatat tcgtgataaa gccctcaaaa gtctcctagc
    15421 agggaaattt ctaaaagcta gagataagaa cattgtcttt aatgtcgaag ttccagagga
    15481 gattcaggta gaggggatga gtctacttga ttttctaacc gttgtgtcta tcctttgtga
    15541 caacgctatt gaagctagtg tagaagcctg tcaacctcat gtttcaattg cctttttaaa
    15601 aaatggagca caggagacct ttatcattga aaattccatc aaagaagagg gaatcgatat
    15661 ttctgaaatc ttctcctttg gagcaagttc taaaggggag gagagaggag ttggtctcta
    15721 taccgttatg aaaattgtgg aaagtcatcc caataccagt ctcaatacca cctgccaaga
    15781 tcacgttttt cgtcaggtac ttactgtaat acatatagaa tgaagaaaaa ataagaccga
    15841 gagtgcgttc tcttggtctt gtttttttat agttgtattg gctgatgaaa tccttttgta
    15901 tttttttgtt caattatatt aaatctatat aagaaatctt cccaccatcc tccacctata
    15961 atttggttga gttcggtagt tgttagttct tgaaatgaag ttaggttttg tttcttatcc
    16021 atgttatgat tctccttttt gataagataa taaatagtta tagagtgtta tctgaaaatt
    16081 aatcagaatg tgttaaaatt ttatctttga aataatcaaa atatgttttc tttgtagtta
    16141 cactagtgac gcgaccttgt aagccatatt ggatgagttt actatcctcg ttagatagtt
    16201 ttgcaagagc ggttaattta aagagattgc cttgctctgt tctggtagga gtttgatcaa
    16261 tactctgaag ttggccgatg atggtggtgc cgtgatttcc aatcttctcc agttttaatc
    16321 ttacagtttg tcctttatct agtaagagga gatagtcaga tgatacgtag taagtgatta
    16381 gtacttctct tgtatctgtg atgacaggga atatttgagc aatttctgta ccagttggaa
    16441 ttctattttt accttcaaat tcgctgttca gatgaacgat acctttactt ggagcggtta
    16501 aggtattatt ttctaagcgc tgtgtcgctt gatctagttg tacttttaat tctgttaatt
    16561 gattctccac ggttagttgt tgctgtgagg ctgtttgtaa aaactgagtg cggagtactt
    16621 caattttggt tgctaaacta ttatcataag ttgctacact tccgatacca gcttgctgaa
    16681 ttttgaggct tgcgatagat gattcaagac ttgcaatact ttgattaatt tgagataaaa
    16741 atggctcctc tgccgttcct tgtgtttgtc cttgagaggc tataagataa cgatttaaaa
    16801 ttgactggtg cggattgcca gttggtaagc gtgctctgtt atttatgata gcatctctca
    16861 actcttgata ttctccaatt tgttgttgaa cttttgtaat ttcttgttcg atggctgatg
    16921 aactgctatt ggcaagatta gcttgatttg aaacttcggt gttagtcttt gtgataccca
    16981 gttcaatatc atgggattgt ttagtaaaat tcataaaggt attatggtag ccaaactcat
    17041 cctcgccaga aaaaagatca gtcgcttttt ctaaactttg tttcaaaatt ccaagtcctt
    17101 ctttttgctt ctcaagtctt tgtaattgag tttctaaggc agttttctga ctctcatcca
    17161 ttgtttcaga gtatttgatg agtaagtcac ctttttcaac tacttgattt gccactaaat
    17221 gattagcaag gataggatta tcactggttg actgaatgga tgcaatgaca cttgtagggg
    17281 cgatttctcc ttgggaagta acagtaattt cttttgtggc aacaagggag aaaatcaaga
    17341 tgaaagtaaa cagtaatgaa agaggtataa ttaacactgt cgcatagtta tggtaacgtc
    17401 tctgataaaa ctcgacgctt ctaaaaagat taggattcat gacattctcc ttatttattg
    17461 aacagatgat ggtagaagcc ttgcgcctgc attaactctt ggtgactacc aacttcaatg
    17521 attttcccct ggtcaagaac aatgacacgg ttagttcgtt cggctatact gagacgatgg
    17581 gctacaaaga gaatggtttt atcagttagg gacataagat tatctataac ttttttctca
    17641 gtcaagacat caagaccgct agtagcttcg tctagtatta aaacaggaga tttagttaaa
    17701 agagcacgag cgagggctat tcgttgcttc tgtcctcctg atagaccagc tccatcagag
    17761 agctgagttt gatagcccat aggcattctt tcaatgtctt gacggatttc agctaattca
    17821 caagctctta gaatatcttc ttggctaatc atatgattac cgcccaaggt taaattttcc
    17881 aagatagagc cattaaagat ataggcttgt tggggtaggt aattaatatg acggcgcaag
    17941 acttttttat caatgttttt aatatcctga tgattgatgg aaatatgccc tttgtagggt
    18001 tcaaagaaat tgacaatcat tttggctaaa gttgttttac cagaaccact aactccaact
    18061 aggctaacct tatctccttg tttaatcgtg agattaatat ctgttaaggt atctcgtcca
    18121 aaaccatact tataagaaag gtcatcaaat tcaatatcgc ccatcaaaaa atgtgaatgg
    18181 acagggtttt cttgaacttg aaattcagat tcgactagat agacttcgtt caaacggtta
    18241 ttagcgacct tcgcagatgg gagtttggtt tggaggttga taatattttc cataggagtt
    18301 gtaaagtaag aaaaaagtgt gttaaaggta atcagctgac cgatagaaat tttactcgac
    18361 atgactaatt gagcgccaaa ccataggata aggatattca gaactaattt tgttccctgc
    18421 tttaaactcg tttgtaaaat agaatattta ctgagcttaa aggatttttc caaataatct
    18481 acaaattcgc tgtctatatt ttgatagcga ttttcttcac tcgtgagcga ctttatagtt
    18541 tcaatcccgt tgatatcttc gataatggca gagctaacca tagaattact ttgcatgaca
    18601 tcatggttca ttttttcaaa aggtttcata aaagaaaaga tgatgaacat gtatatagga
    18661 atggaaagaa gagaaaggag gaagagatta gggttttgtg ccagcaagac tccccctaca
    18721 agaatcagaa tagaaacatc cagaaaaaga gaaagaatgg tagaagccaa ggcatctata
    18781 atagagttag catctgtgaa ccgtgaaatg atttctcctg tacgacgtgt cgcaaagaaa
    18841 gacatgggaa gttcaaaaat atggcgaata taggataaaa tcacatcaat gcttaatctc
    18901 tggctcagaa cggttaggag ataatctctg gagaagctca tgacttgttg gaggatatag
    18961 gtgataacct aggtgataac cagaccaact gagatgattc ctaaagttga tttcatctga
    19021 tttggaatgt attcatccaa gattccttgg agatagtaag aaccacctat attgataata
    19081 gtgaccaata agcttgagag aacaatgtaa gcaatgagag atttttgttt gaaaatcaga
    19141 ggaaggaagc ttgcttagta gaccattctt tttatcttta tggggttgat agctgggttt
    19201 ggtagctaga aaaatagcta ctccagtcca ttcatagaaa aagcgttctt ttgacatttt
    19261 agtgattttt acagaagggt caggatcacc aataatcaga tagtctttct ttgtttgata
    19321 gacaacatag taatgttgga gttttccttc tttgttaacg tgaacgataa atggataggg
    19381 gacatcactc atgtcaaaga gcgttttatc tgcttgaaca ggtcttgttt caaagcccat
    19441 ttcatcagcg gcttttacaa tgccaagagc agtcgtccct tctttattgg tctttgcaag
    19501 ttctctcaag tgagctagag aaaaatctga accatagaat ttagcaatcg aggctaaggc
    19561 agcgacacca cagtctctcg catctatttg aggaacaaat gtacgtttat aagaagtcat
    19621 tggcaattct tttcatatag tggataggtc tattatgtca taaaactaag ttcatatttt
    19681 atgaaatctt gaatagtcat taaaacttcc tgaatggtaa aaaagtgatt agaaattatt
    19741 ttttttaaac atttagaggt ggcttgaaat aaaaaagcta attcaagacg tttcgatgac
    19801 aattcaagat ctggatgaaa aattttaaaa aacgatgata tactaaactt atcaaagtta
    19861 caacaagaca aaaataaaaa aagaaaaaag gagtatttgt catgaataca aaaatgatgg
    19921 aacaattttc tgttatggat aatgaagaac tcgaaatagt tagtggagga agaggcaatt
    19981 taggatctgc aatcggtggt tgtattggag cagtactatt agctgctgcg actggtccga
    20041 taactggggg agcagcaaca cttatttgtg taggttcagg aattatgtcc tctttgtaag
    20101 attatgattc ttaaatatag tattattatc gctattaatt tactgtctta tttacttact
    20161 tacaaaatat caaagttatc taagaatgat gagaataaga tagttagcaa aattttaatt
    20221 atattatcaa tcgtttatgt aatcgttgat gctttactta gttgatggat tggtaggaat
    20281 aaaaaactta actataaact attatttact aatatttttt gctttctgca agttaataaa
    20341 tagtatagta aaacttttta ttgcaaggag aataacgaaa ttaagatatt ttagatactc
    20401 aagattattg aaatcttaga ctaaaaaata ggtactgcta cctttaagaa gatagtagac
    20461 gtatatactt ttttaagaaa atcaaaaaga tactataaaa aatctatttg tttattgaat
    20521 ttaagacttt ggtaacaaat tgaaaataaa aaggaggtat tcatcatgaa tacaaaaatg
    20581 ttgtcacagt tagaggttat ggatactgaa atgcttgcga aagttgaagg ggggtatagc
    20641 tccactgatt gtcaaaatgc actgattaca ggagtcacta cgggaattat aactggtgga
    20701 actggagcag gtttggccac tttaggagta gctggacttg ctggtgcatt tgttggagca
    20761 cacattggtg caattggggg tggattaaca tgcttaggag gtatggttgg tgataaattg
    20821 ggactaagtt ggtaagactt atagtaaaat tatgaggatt ctattctgat ttattttagt
    20881 tttttaaaaa aggagtattt gtcatggata caaaaatgat gtcacaattt tctgttatgg
    20941 atactgaaat gcttgcttgc gttgaaggtg gcggatgcaa ttggggagat tttgccaaag
    21001 caggtgttgg aggagcagca gcaagaggtc ttcaactagg cattaaaaca ggaacatggc
    21061 aaggtgcagc aactggtgct gcgggtggag ctatacttgg aggtgtagcc tatgcagcaa
    21121 catgttggtg gtaattatgg attttaaaag ttttattatt ggtttagtag ttggtatatt
    21181 tggtccttat atgtataatt taattagaaa aatattttca aaatttccca aaaaggatac
    21241 agatagtacc ccctaaaaaa taaatttctc ccctgtattt gctagcttaa tttacagggg
    21301 agtttcttta attttgtttc gcctgtcaaa atgatatgtg atagcaggat gaaaagtcta
    21361 caaacaagtt ggtatcaata caatataaag aggaaagtat gtttttaatg cttacttttt
    21421 aaatttttta acaattcaag atgtttcgat gaccatttat gatttgagtg atccaaggtc
    21481 aaaataagtg ctatactagc agtgtaaatg ttcttgctca actaagataa atcgcacatt
    21541 taggaggaaa tcttatgaag aaaaaaatac tgattatttt cgttctgtat ctaatcatgt
    21601 ccatctttct atatccgctt agggagagtg cttggtatca gctattttat accatagcct
    21661 atgtgattgc agttatgatc tattttgcta tcaataaaaa gaaaggagaa aagaaatgaa
    21721 aacttttttt gctaaaaaac ggaacatctt ccttgcgaga ttgttcttag gtcagttgcc
    21781 cttgcttgtt tctacttatc tatttctatc tcgtcagttt ttaaattttt ccgtagtttt
    21841 ccaatttctt ttagtagtta ttaacttggc ttctattttg gttactgttt atctcactag
    21901 ggaaatgagg ataagagagt ttgaagatga tgatttggtt agtcctagaa ccaatcaact
    21961 tatgtttatc ggcttggcag attttatgtt tgtcatttgt ttgtatagag gtatttcaga
    22021 aacagaattc tatcaacaac taatcgctta tataggtgta ttctctgctt gtttatcacg
    22081 cttctgctca tgtggggctt gaagtattat aaaaagtagc tttctatcct tttctgacag
    22141 gatatttgag tagaaggctc tattaaattg ttagtgaaat aaatgaatgg aggtatttaa
    22201 tatgaaatac agattatttt ttgttatttt cttgagtagt gtgttggata ttcttttagg
    22261 gacattttta caaatctcta tcgtatctat tgggtggctt gttctttaca gtggtttgtt
    22321 tgaagtagga gttttccttc ttgctaataa aggggtggcg gtaaaaatca aggaagtaga
    22381 tattcgaaat cgctttaaat ttatttttgg aaaaacctta tggtttcaaa ttcttttgct
    22441 catctttttg ataatcaaac tttatcttgg tttggatgcg aggttgattt tattctatgg
    22501 acatattttc attgtcttta atgccttaat gtatctatta tctagtagtc aggttagcct
    22561 taaaaaaaaa caaactgtct tcttaatctt acagcagtag agtctgacaa ggtgaggtca
    22621 tagtagggag gatttctatg aaaaagtatc aacttctatt caaaataagt gcagtcttct
    22681 cttacttatt tttcgtattt ggtctttctc agctgacgct tatcgtccaa aattattggc
    22741 aattttcttc ccagattggt aatttcgtct ggattcaaaa tatcttgagt ttacttttta
    22801 ttggagtcat gattgtggtt cttgttaaga caggccatgg ttatctcttc cgcattccaa
    22861 gaaaaaaatg gctttggtat tcgattttga cagtattagt ggtagtgttc cagatctctt
    22921 ttaacgttca gacagctaaa catgttcagt caactgcgga aggttgggct gtattgattg
    22981 gttatagtgg gactaacttt gcagagctag gtatttatat agccctgttc tttctggttc
    23041 cactgatgga agaattgatt tatagaggat tactgcaaca tgctttcttt aagcattcgc
    23101 gatttggtct tgatttgctt cttccttcta ttttatttgc tctccctcat ttttcaagcc
    23161 tgcctagtct gttagatatc ttcgtctttg caacagttgg aatcatcttt gctggtttga
    23221 cccgctatac caagagcatt tatccatcct atgcggtgca tgtgatcaat aatattgtag
    23281 cgaccttccc gtttttgctc acttttctac atagggtctt ggggtaaaaa aacaaaaggc
    23341 ttgcttttca gccatagagg aggtcatcat gtataaacac ttatttttcc tagattccaa
    23401 aactttagat cggttgacac cctatattct agtcttggct tctgacacca ttgcttttaa
    23461 tgtttttgtg ctaacctttg tatctgcggt ggtttttaat ttcctaaatt ccatgctagc
    23521 tttaatggct atattcatag gggctggcta tgtggtcgga ttttggttgc taaaatggtt
    23581 tgttttggaa aggttagagc taaaggatga cgcgtaggaa gtctgtttgg tgaggaggat
    23641 agttttatgg agttttttga taaatttcat gccttgtgtt ttggattttt agtactaata
    23701 attgtcatta cagttcctta tacgattaac catgggggtt tttttcaaaa tgaatctgca
    23761 ttgattcttg taagtcttct tgtaacctcg ctgagtgttg cttatgctag aaagtttgaa
    23821 atgatttctt ttgggatgtt aagcaagaaa caacttttgc ttttcattgc aatctttctt
    23881 ctaagtgtac ttgagacgct ggtttatatt catttcttcg ctgtttcttc tggctcaggg
    23941 gtccaacact tggcggaagt cagcagagga atttccctgt ctttgatttt gactacctca
    24001 gtttttggcc ccatccagga ggaactcatt ttcagaggac ttcttcaagg tgcggttttt
    24061 gacaattctt ggttagggct tgtgctaact tcctctctct tttctttcat gcatggacct
    24121 tctaatgtcc cttcgtttat tttttatcta cttgggggtt tgttgctggg ctttgcttat
    24181 aaaaagagtc aaaacctatg ggtttctact ctagtacaca tgttttacaa cagttggcca
    24241 ctcctatatt atttataaaa attatgaaaa ggtaagcaga agacggtgct tacctttttc
    24301 aagctataat gatacccaag ccaatccaga ggcttttctt tgagaatcgg gttagagtgg
    24361 ttgacgaata ggccaaaaac tagtagaata gtaaggaaac tttatacgga ggaaagaaat
    24421 ggatttgggt gataatgagc taacactgac tcccatacct gggaaaagtg gcaaggctta
    24481 tatgggtagc tatcctgacg ggaagcgcat ctttgtaaaa atgaacacct ctccaatcct
    24541 acctggtcta gctagagaac aaattgctcc acaattatta tggagtcgtc gtttggcaga
    24601 tgggcgtgat atgtgtgctc aagaatggtt gacaggcaag atattgaccc cctatgatat
    24661 gaatcgtaag caaatcgtca atattttaac ccgtcttcat cgctcacgtc cgttgatgac
    24721 acaattgagt cgtttgggct atgccatgga aacacctgta gatttactac agtcttggca
    24781 ggaaacggct ccagatgctt tgcgtaaaaa tcattttatc agtgaagtga tggctgattt
    24841 acgtcagact attccaggat ttagagagga ccatgcgacc attgtccatg gagatgtacg
    24901 acatagtaat tggattgaga cagatagtgg cttgatttat ttagtagatt gggattcggt
    24961 tcgcttgacc gatcgcatgt ttgatgtggc ccatatgctc tgccattata tttcagaaca
    25021 tcagtggaag gaatggttga cctactacgg ttacaagtac aatcaaacgg tattaagtaa
    25081 attgtattgg tatggtcaat tgtcttattt gagtcagatt tccaagtatt atatgaacca
    25141 agatttagaa aatgtcaatc gggagattca tggtttgcgt catttccgag acaagtatgg
    25201 aaagagaaga tgagagttag aaatcgtaaa ggggcaacag aattactaga ggcaaatccc
    25261 cagtatgtgg tcctcaatcc cttggaagcc aaggcaaaat ggcgggactt gtttggcaat
    25321 gataatccca ttcatgtgga agttggaagt ggaaagggtg cctttgtttc aggtatggcc
    25381 aagcaaaacc ctgacatcaa ctatatcggg attgatattc aaaagtctgt tttgagctac
    25441 gctttggaca aggtgcttga agttggagtg cctaacatca agctcttgtg ggtagatggt
    25501 tctgacttaa ctgactattt tgaagacggt gagattgatc gcttgtatct gaacttttca
    25561 gatccatggc cgaaaaaacg ccatgaaaag cgtcgtttga cctacaagac cttcttggat
    25621 accttcaaac gtatcttgcc tgaaaatgga gaaattcatt tcaagacgga taaccgtggc
    25681 ttgtttgagt acagtttagt gagcttttct caatatggca tgaaactcaa tggtgtctgg
    25741 ttagatttgc atgccagtga ttttgaaggc aatgtcatga cagaatacga gcaaaaattc
    25801 tcaaacaagg ggcaagttat ctaccgagtt gaggcagaat tttaagagat agcctaaaat
    25861 taggctgtac aagtgctttt gctttacata agttggcaaa cgtgctatac tgatagtaag
    25921 aatatgaaaa gtgaggcggg gaaatatctt cgcctcttgc ttatgaggag gtggacgcaa
    25981 tcgcaacaat cgtagaatta gtcagagaag ttgtagaacc tgtcatagaa gctccttttg
    26041 aactcgtgga tatcgagtat ggaaagattg gcagtgacat gattctcagt atttttgtag
    26101 ataaacccga aggaattacc ttgaacgaca cggcagactt gacagaaatt atcagtcctg
    26161 tcctagacac catcaagcca gatcccttcc cagaacaata tttcctagaa attaccagtc
    26221 caggtttgga acgccctttg aaaaccaagg atgccgtcgc tggagcggtt ggaaaataca
    26281 tccatgtcgg gctctaccaa gccatcgata agcaaaaggt ctttgaagga accttgttgg
    26341 ccttcgaaga ggacgagttg actatggaat atatggacaa gacgcgtaag aaaaccgtcc
    26401 aaattccata cagtttagta tcaaaagcac gtttagcagt taaattatag aaaaagaaag
    26461 gatagctttt gaggattcaa aagtgaagaa aacatgagta aagaaatgct agaggccttc
    26521 cgcattttgg aagaagacaa gggaatcaaa aaagaagata tcatcgacgc agtagtagag
    26581 tcgcttcgtt ccgcttatcg cagacgctat ggtcagtcag acagcgtagc tattgacttc
    26641 aacgaaaaaa caggtgactt tacagtttat actgtccgtg aagttgttga tgaagtattt
    26701 gatagccgtt tggaaatcag cttgaaagat gctcttgcca ttaattcagc ttatgaactt
    26761 ggagacaaaa tcaagtttga agaagcacca gctgagtttg gtcgtgtagc agcccagtct
    26821 gccaaacaaa ccatcatgga aaaaatgcgc aagcaaacac gtgccatcac ttacaatact
    26881 tacaaagaac atgagcaaga aatcatgtct ggtacagtag aacgctttga caaccgcttt
    26941 atctatgtca accttggtag catcgaagcc caattgtcaa aacaagacca aattcctgga
    27001 gaagtttttg cttctcatga tcgtatcgaa gtttatgttt acaaggttga agacaaccct
    27061 cgtggtgtga acgtctttgt tagccgtagt catccagaaa tgatcaaacg tttaatggag
    27121 caagaaattc cagaagttta tgatggaact gttgaaatca tgagcgtggc tcgtgaagca
    27181 ggtgaccgta cgaaggttgc tgttcgtagc cacaatccaa acgtggatgc tatcggtaca
    27241 atcgttggac gtggtggtgc taatatcaag aagattacta gcaaattcca cccagctcgt
    27301 tacgatgcta aaaatgaccg catggtacca atcgaagaaa atatcgatgt tatcgagtgg
    27361 gtagcagatc cagctgaatt tatctacaat gccatcgctc ctgctgaggt tgaccaagtt
    27421 atctttgatg aaaacgacag caaacgtgcc ttggtggttg ttccagataa caagctttct
    27481 cttgccattg gtcgtcgtgg acaaaacgtg cgcttggcgg ctcacttgac tggttaccgt
    27541 atcgatatca agtctgctag cgaatttgaa gccatggaag acgctgcttc agtagagttg
    27601 gaagtagaaa acgatactgt agaagaataa aagctgctag aggagggaaa gatgaaaaca
    27661 agaaaaatcc ctttgcgcaa gtctgttgtg tctaacgaag tcattgataa gcgtgatttg
    27721 ctccgcattg tcaagaacaa ggaaggacaa gtctttattg atcctacggg caaggccaat
    27781 ggccgcggcg cttatatcaa actagacaat gcagaagccc tagaggcgaa aaagaagaag
    27841 gtctttaacc gcagctttag catggaagtg gaagaaagct tttatgacga gttgatcgct
    27901 tatgtggatc acaaagtgaa aagaagagag ttgggacttg aataagcaaa agataagtaa
    27961 tctcttgggg cttgctcagc gagcagggcg catcatatcg ggtgaagaat tggtggtcaa
    28021 ggccattcaa gacggcaagg ccaagttggt ctttctagct catgatgctg gacccaatct
    28081 gaccaagaag attcaagata aaagtcatta ttatcaagta gaaattgtaa ccgtgttttc
    28141 aacactggaa ttaagcatag cagtcgggaa atcgagaaag gttttggctg taacagatgc
    28201 tggatttaca aagaaaatga ggtctcttat ggaatagaag aggaggacat gatttgtcta
    28261 agaaaagatt gtacgaaatc gcaaaagaac ttggaaaaga aagtaaagaa gttgtagcgc
    28321 gtgcaaaaga gttgggcttg gatgtgaaaa gccactcatc aagtgtggaa gaagctgtcg
    28381 ctgcaaaaat tgctgccagc tttaagcctg cagctgctcc gaaagtagaa gcaaaacctg
    28441 cagcaccaaa agtaagtgca gaaaagaaag ccgaaaaatc tgagccagct aaaccagctg
    28501 tagctaagga agaggcaaaa ccggctgagc cagttgctcc gaaaacagaa aaagtagcag
    28561 tgaaaccgca aagtcgtaat ttcaaggctg agcgtgaagc ccgtgctaaa gagcaggcag
    28621 aacgacgcaa gcaaaataag ggcaataacc gtgaccaaca acaaaacgga aaccgtcaga
    28681 aaaacgacgg ccgtaatggt ggaaaacaag gtcaaagcaa ccgcgacaat cgtcgcttta
    28741 atgaccaagc taagaagcag caaggtcagc aaaaacgtag aaatgagcgc cgtcagcaag
    28801 aggataaacg ttcaaatcaa gcggctccac gtattgactt taaagcccgt gcagcagccc
    28861 taaaagcaga gcaaaatgca gagtacgctc gttcaagtga ggaacgcttc aagcagtatc
    28921 aggctgctaa agaagccttg gctcaagcta acaaacgcaa ggaaccagag gaaatctttg
    28981 aagaagcggc taagttagct gaacaagcac agcaagttca agcagtggtt gaagtcgtcc
    29041 ctgagaaaaa agaacctgca gtggatacac gtcgtaaaaa acaagctcga ccagacaaaa
    29101 atcgtgacga ttatgatcat gaagaagatg gtcctagaaa acaacaaaag aatcgaagta
    29161 gtcaaaatca agtgagaaat caaaagaata gtaactggaa taacaacaaa aagaacaaaa
    29221 aaggcaataa caagaacaac cgtaatcaga ctccaaaacc tgttacggag cgtaaattcc
    29281 atgaattgcc aacagaattt gaatatacag atggtatgac cgttgcggaa atcgcaaaac
    29341 gtatcaaacg tgaaccagct gaaatcgtta agaaactttt catgatgggt gtcatggcca
    29401 cacaaaacca atccttggat ggggaaacaa ttgaactcct catggtggat tacggtatcg
    29461 aagccaaaca aaaggttgaa gtggataatg ctgacatcga acgtttcttt gtcgaagatg
    29521 gttatctcaa tgaagatgaa ttggttgagc gtccaccagt tgttactatc atgggacacg
    29581 ttgaccacgg taaaacaacc cttttggata ctcttcgtaa ctcacgtgtt gcgacaggtg
    29641 aagcaggtgg tattactcag catatcggtg cctaccaaat cgtggaaaat ggtaagaaga
    29701 ttaccttcct tgatacacca ggacacgcgg cctttacatc aatgcgtgcg cgtggtgctt
    29761 ctgttaccga tattacgatc ttggtcgtag cggcagatga cggggttatg cctcagacta
    29821 ttgaagccat caaccactca aaagcagcta acgttccaat catcgtagcc attaacaaga
    29881 ttgataaacc aggtgctaac ccagaacgcg ttatcggtga attggcagag catggtgtga
    29941 tgtcaaccgc ttggggtgga gattctgaat ttgttgaaat ctcagctaaa ttcaaccaaa
    30001 atatcgaaga attgttggaa acagtccttc ttgtagctga aatccaagaa ctcaaggcag
    30061 acccaacagt gcgtgcaatc ggtacggtta tcgaagcgcg cttggataaa ggaaaaggtg
    30121 cggtcgcaac ccttcttgta caacaaggta ccttgaatgt tcaagaccca atcgttgtcg
    30181 gaaatacctt cggtcgtgtc cgtgctatga ccaacgacct tggtcgtcgt gttaaagttg
    30241 ctggaccatc aacaccagtc tctatcacag gtttgaacga agcaccgatg gcgggtgacc
    30301 actttgccgt ttacgaggat gaaaaatctg cgcgtgcagc aggtgaagag cgtgccaaac
    30361 gtgccctcat gaaacaacgt caagctaccc aacgtgttag ccttgaaaac ctctttgata
    30421 cccttaaagc tggggaactc aaatctgtta atgttatcat caaggctgat gtacaaggtt
    30481 ctgttgaagc cctttctgcc tcacttcaaa agattgacgt ggaaggtgtc aaagtgacta
    30541 tcgtccactc agcggtcggt gctatcaacg aatcagacgt gacccttgcc gaagcttcaa
    30601 atgcctttat cgttggtttc aacgtacgcc ctacaccaca agctcgtcaa caagcagaag
    30661 ctgacgatgt ggaaatccgt cttcacagca ttatctacaa ggttatcgaa gagatggaag
    30721 aagctatgaa agggatgctt gatccagaat ttgaagaaaa agttattggt gaagcggtta
    30781 tccgtgaaac cttcaaggtg tctaaagtgg gaactatcgg tggatttatg gttatcaacg
    30841 gtaaggttgc ccgtgactct aaagtccgtg ttatccgtga tggtgtcgtt atctatgatg
    30901 gtgaactcgc aagcttgaaa cactataaag acgacgttaa ggaagttaca aacggccgtg
    30961 aaggtggatt gatgatcgac ggctacaatg atattaagat ggatgatgtg attgaggcgt
    31021 atgtcatgga agaaatcaag agataagatt ttttgctcct ttcttaggtg gtgagggacg
    31081 caagcaaacc gatggtttca ttgcttattt ttgagcctag ggtctcaaaa atcccctgtg
    31141 atgggactga taaatcagtt ccatcacttt caccacggcg aaagaagcag atgacttcaa
    31201 attgaacttc gtttcaattt aaactgaaaa tcaagaagtt taaaatagct aggtctgctg
    31261 gcctagcttt tggttcaaag tagagaaagg aatatcatgg caaatcattt ccgtacagat
    31321 cgtgtgggca tggaaatcaa gcgtgaagtc aatgagattt tgcaaaagaa agtccgtgat
    31381 ccacgtgtcc aaggtgtgac catcacagat gttcagatgc tgggtgactt gtctgttgcc
    31441 aaggtttatt acaccatttt gagtaacctt gcttcggata accaaaaagc ccaaatcggg
    31501 cttgaaaaag caactggtac catcaaacgt gaacttggtc gcaatttgaa attgtacaaa
    31561 atcccagatt tgaccttcgt caaagacgag tccatcgagt atggaaacaa gattgacgag
    31621 atgctacgca atctggataa gaactaaaga agaggggttg cccctctttt tcggctcttt
    31681 gtcaactgta gtgggttgaa
//
LOCUS       DAVBIC010000023        31002 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.023, whole genome shotgun sequence.
ACCESSION   DAVBIC010000023 DAVBIC010000000
VERSION     DAVBIC010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31002)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31002)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31002
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.023"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            complement(298..516)
                     /locus_tag="VQ664_001021"
     CDS             complement(298..516)
                     /locus_tag="VQ664_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001207345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2789197.1"
                     /translation="MVLNYKPLWIQLAKKGLKKTDVIAMAGLTTNVMAQMGKDKPITF
                     KNLERICKALSCTPNDIISFEDNFSDEE"
     gene            complement(762..1040)
                     /locus_tag="VQ664_001022"
     CDS             complement(762..1040)
                     /locus_tag="VQ664_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789198.1"
                     /translation="MKKDKEVYDKVCEYLSPHLNKDMEMLELACWFRVIIVIEANSYV
                     NIRSSRLLPKFKTQKINSWCAAYSIHFNNGYCKQHTNEFKDSLKSLIL"
     gene            complement(1254..2885)
                     /gene="rlmD"
                     /locus_tag="VQ664_001023"
     CDS             complement(1254..2885)
                     /gene="rlmD"
                     /locus_tag="VQ664_001023"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HET2789199.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMR
                     VLKVNKKIGFGKVEKYLVQSLHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHNLMPLEDFF
                     IQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWCTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDDVVIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSQKNASLNKITNAHYVCDTAENAMKKWLKEGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSK
                     LDVDKHISVEIELDEMDLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIEL
                     REHYNKSKKDKQIIPQCTPEKEEAIMDALRHFKMI"
     gene            complement(2959..3933)
                     /locus_tag="VQ664_001024"
     CDS             complement(2959..3933)
                     /locus_tag="VQ664_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HET2789200.1"
                     /translation="MRKKLFLTSAAVLWAVTAMNSVHAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGMEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDVRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQALVNFFKSFGS"
     gene            complement(4007..4621)
                     /gene="pmp23"
                     /locus_tag="VQ664_001025"
     CDS             complement(4007..4621)
                     /gene="pmp23"
                     /locus_tag="VQ664_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HET2789201.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     KDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNTTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVRLNLYIIKCFTLFSTSG"
     gene            complement(4621..5595)
                     /locus_tag="VQ664_001026"
     CDS             complement(4621..5595)
                     /locus_tag="VQ664_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HET2789202.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSRKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDASRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQKENGTYSILIKNIEDIQSK"
     gene            complement(5603..6859)
                     /locus_tag="VQ664_001027"
     CDS             complement(5603..6859)
                     /locus_tag="VQ664_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HET2789203.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMSLIEPGDTVMGMDLASGGHLTHGAPVSFSGQTYNFVSYSVDPETELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEELAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYETLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFPLYEE"
     gene            complement(6921..7352)
                     /locus_tag="VQ664_001028"
     CDS             complement(6921..7352)
                     /locus_tag="VQ664_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000942930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2789204.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSPEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGQGIGKSLLQGLEQEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKMQKRFIRIF"
     gene            complement(7354..7956)
                     /locus_tag="VQ664_001029"
     CDS             complement(7354..7956)
                     /locus_tag="VQ664_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HET2789205.1"
                     /translation="MMDRIRQELENGGAVVLPTETVYGLFAKALDEKAVDHVYQLKRR
                     PRDKALNLNIASFEDILHFSKNQPTYLQKLVETFLPGPLTIILEANDRVPYWVNSDLA
                     TIGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFL
                     TGQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEA"
     gene            complement(7940..8779)
                     /gene="prmC"
                     /locus_tag="VQ664_001030"
     CDS             complement(7940..8779)
                     /gene="prmC"
                     /locus_tag="VQ664_001030"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HET2789206.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPDWSVTAADVSQEALELASENASDQNLN
                     IFFKKSDCFAEISEKYDIIVSNPPYISREDESEVGLNVLHSEPHLALFADEDGLAIYC
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPELFRKHLPEKKVRTLKDQFGQNRMVVVDD
                     GQD"
     gene            complement(8779..9858)
                     /gene="prfA"
                     /locus_tag="VQ664_001031"
     CDS             complement(8779..9858)
                     /gene="prfA"
                     /locus_tag="VQ664_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HET2789207.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEEMAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            complement(9855..10445)
                     /locus_tag="VQ664_001032"
     CDS             complement(9855..10445)
                     /locus_tag="VQ664_001032"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000068157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HET2789208.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGYIRGLPEKPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFAPEINKENEEK"
     gene            10568..10750
                     /locus_tag="VQ664_001033"
     CDS             10568..10750
                     /locus_tag="VQ664_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HET2789209.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            10887..12260
                     /gene="mnmE"
                     /locus_tag="VQ664_001034"
     CDS             10887..12260
                     /gene="mnmE"
                     /locus_tag="VQ664_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HET2789210.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIAQKIFKGKDL
                     NKVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNIRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTKLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEANLVLLVLNASEPLTAQDRQLLEISQDTNRII
                     LLNKTDLPETIETSKLPEDVIRISVLKNQNIDKIEERINNLFFENAGLIEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(12307..13242)
                     /gene="dapA"
                     /locus_tag="VQ664_001035"
     CDS             complement(12307..13242)
                     /gene="dapA"
                     /locus_tag="VQ664_001035"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HET2789211.1"
                     /translation="MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKTIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     HPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAILNYMGFEAGPTRLPL
                     VPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(13298..14374)
                     /locus_tag="VQ664_001036"
     CDS             complement(13298..14374)
                     /locus_tag="VQ664_001036"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HET2789212.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGSSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPCDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIAAF
                     PGAVLEDDVAHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(14716..14788)
                     /locus_tag="VQ664_001037"
     tRNA            complement(14716..14788)
                     /locus_tag="VQ664_001037"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(14753..14755),aa:Thr,seq:ggt)
     gene            complement(14888..15397)
                     /locus_tag="VQ664_001038"
     CDS             complement(14888..15397)
                     /locus_tag="VQ664_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HET2789213.1"
                     /translation="MKKLTIRDIADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(15395..15491)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            15520..15951
                     /locus_tag="VQ664_001039"
     CDS             15520..15951
                     /locus_tag="VQ664_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HET2789214.1"
                     /translation="MKIPIQKFFNNEILAYLFFGLATTLVSILSRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKAYIFRK"
     gene            16033..16410
                     /gene="mscL"
                     /locus_tag="VQ664_001040"
     CDS             16033..16410
                     /gene="mscL"
                     /locus_tag="VQ664_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HET2789215.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKKE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(16452..17546)
                     /gene="hemH"
                     /locus_tag="VQ664_001041"
     CDS             complement(16452..17546)
                     /gene="hemH"
                     /locus_tag="VQ664_001041"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HET2789216.1"
                     /translation="MKKAILMMTFGSPEEISFEGVAEFFTNIRRGVRPQDHEIQTLYD
                     NYIRIGGTPLQRITREEVNLVKERLGEEYGIYFANKFSRPFIPDVIKQMETDGVEECI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEVLLNYWADEIAKILKEEVKQD
                     SFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSEQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTEHPDHYIFVPISFISEHIEVLFDNDVECYDLCQEFGVNYHRPPMP
                     NTDSRLIDALVNTVRVNENQEFKEFLPEEETFDELVPSDETKNILAESEDLQMPEFVK
                     KLIEKKGRENVKMPYLIKKMLEKAGKLPKE"
     gene            complement(17624..18456)
                     /gene="srtG2"
                     /locus_tag="VQ664_001042"
                     /pseudo
     CDS             complement(17624..18456)
                     /gene="srtG2"
                     /locus_tag="VQ664_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000218039.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PI-2 pilus system class B sortase SrtG2"
     gene            complement(18534..19532)
                     /gene="srtG1"
                     /locus_tag="VQ664_001043"
     CDS             complement(18534..19532)
                     /gene="srtG1"
                     /locus_tag="VQ664_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000851047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-2 pilus system class B sortase SrtG1"
                     /protein_id="HET2789217.1"
                     /translation="MKTKREKPKKSLSRRLVLAVDGVINHLLLIFAALIFLFGFYALW
                     DSNQVYSLASSSEYEAYRPVTTQQDELASFSGFSKLQELNPEVLGWINVYGTNIDYPL
                     VQAKDNEKYLNKDSKGEFAATGAIFLDARNNPKFEDFNTIIYGHHVENGVMFGDVAKF
                     ADQEFFDQHRYGSIYYNGVEKGLEIFEMLEVDAYDFNIYDPGIQGEDRQQAYLDHLLS
                     VAMHKRDISLSPSDRIILLSTCFLDVTNGRHIVVAKITDTVPKNTFHTKKSKPFPYSV
                     FDDSSLGRFLSSIPLWIWYLILFVLFLLLIFLLLVLYLILRRRRESKKNARSRPFY"
     gene            complement(19550..20746)
                     /gene="pitB"
                     /locus_tag="VQ664_001044"
     CDS             complement(19550..20746)
                     /gene="pitB"
                     /locus_tag="VQ664_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-2 pilus major pilin PitB"
                     /protein_id="HET2789218.1"
                     /translation="MKKTFFKKLFTASIAAITALSVFRGVPTFADDNSAITKANGENN
                     AVVKINKTLNIAEGITTPTATFTFKFTEKTGQSSNGAPYQTGVAIPDRNVEYNKNDHP
                     TADKIQKATEDIFSGVAYGHAGEYVYDVAEAKTGWQAITKNGKTIDAMRYDKRTYEMH
                     VIVKNKVNGGVYISSVYFKENNKSNAPKVEPSEQGVYNLFDNTYTKDASKEPNPDDPS
                     QVDPNAKALTITKKVDGASGDKTRDFQFHIKIQLPSTNKTAETPVTNIIVKHGSKSEV
                     LAVVTPADTVEYNFTLKDGETFTVEQLPAGSKYTVTETGVAGYTDSSIYTTNGAEQTS
                     QGQKNVDFTLTDILIGEKKNDNKVTNKIDDVTPTGLLIDNLPFILMIGLGLAGFVVLS
                     KKRREA"
     gene            complement(20791..21342)
                     /gene="sipA"
                     /locus_tag="VQ664_001045"
     CDS             complement(20791..21342)
                     /gene="sipA"
                     /locus_tag="VQ664_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-2 pilus system signal peptidase SipA"
                     /protein_id="HET2789219.1"
                     /translation="MLLKKKHKKPVTQVNRDKSPPSVWGDILYLVSKLLMVGFVLAIL
                     YFFVFGLLRYNDDGMKPALKDGDLVVYYRLDKRYSIGDLLVYSYKGKERVARVIATEG
                     STIDINENGLIINGSPQQEQDIYKETLLYKEGATFPMKVPAGQLFVLGDNRTTAVDSR
                     AFGTIPIQDTQGKVVTVIRRRGF"
     gene            complement(21342..23105)
                     /locus_tag="VQ664_001046"
     CDS             complement(21342..23105)
                     /locus_tag="VQ664_001046"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789220.1"
                     /translation="MIDTPYWFTSGLERGMLNISSLIAPKIDGFYSIKFRYYIGSNDS
                     ITSLKGYISGYNSGIPNEIFSANNENDLQQKFKEITDKILPLGVHHVTISDVLSKYVQ
                     LLPGDASHLRVVKIKDGNEQELNDNQVTIETKKNEQGLVEVTAKFNPSYTLEDDAKYV
                     LKFTVTSSQEAFDAIAGDKTLTSDDAEEADATKLYSNKGAKVAYSYGIGTSRTKIKDY
                     SEKPTFKPSDPLTVPVEIEWKGVDGKSNPSANRPPSVELNLNQKKDGSIKDSYRKVTS
                     PVQTNSFTENTSFAKVAKGYDYELKAPDAPGYTVEVQKTGTKEKPSFKVIYRQLPSLT
                     VKKILEGEQSPNKSFTINVTFSDKDGKPINGKFGNTTVTNGKAQISLKNSQETALSYL
                     PRDTHYKVEEVENSRTGYHVTYEKQEGTLSEDVQTIVTNHRLPTLSVTKKVTGAFANL
                     LQSFKITINVKDAQNKPLNGSYSAIVNNQKTTLQFTNGKATVDLKKDKTIKILDLPLN
                     ARYSIEEEASSSRGYQVSYDKKEGTLDANKSATVTNNKNSVPETGIDFLSSTLVLGVV
                     LPLGGIFFIILLGHLVVNRRK"
     gene            complement(23427..23930)
                     /locus_tag="VQ664_001047"
     CDS             complement(23427..23930)
                     /locus_tag="VQ664_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adhesin"
                     /protein_id="HET2789221.1"
                     /translation="MNVQYDFKKIQYFTSSLVIFLAILFLCAPINSLRADSITEPQTT
                     LHKTITPISGQKDQYELSLDITSKLGTETQSEPLDVVLVADLSGSMEERDVWSYSSRR
                     YISRIEALKHTLKGVNGRQGLIDTILSNSQNRLSIVGFAGKIDNQYNDRYYNEYYLSY
                     QYGTWPN"
     gene            24289..25512
                     /gene="pepT"
                     /locus_tag="VQ664_001048"
     CDS             24289..25512
                     /gene="pepT"
                     /locus_tag="VQ664_001048"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HET2789222.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPRQTLITTDGTTLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKGQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEV
                     RASYIIRDFEKDAFEARKASMQSIADKMNEELGSDRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVAYKG"
     gene            complement(25548..26177)
                     /locus_tag="VQ664_001049"
     CDS             complement(25548..26177)
                     /locus_tag="VQ664_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789223.1"
                     /translation="MNKANQLLEQIHEEGIRQSLAEEVENLKAATNKADADLDEVNSQ
                     VKDVLTRIASALQQEKENAEQDSQTLVLYQKLYDILMSLHSYLESNNGSDADFDKVDA
                     LLDQLSANSKDKTALLESTKAILVLNHQIQSKVSASEETSPARNAEANSDNTSAENQP
                     NATAESNIETASDENKPSNTRDSKPAESTSENETTESSTTTGNQEKPVE"
     gene            26142..26363
                     /locus_tag="VQ664_001050"
     CDS             26142..26363
                     /locus_tag="VQ664_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789224.1"
                     /translation="MDLFQELICLVQKTFYFFLAICRRLLVAIYHVLLKQESYNPRLQ
                     GLTEIRNPDKTMFVQDAIRFAQQHGFNML"
     gene            complement(26634..26982)
                     /locus_tag="VQ664_001051"
                     /pseudo
     CDS             complement(26634..26982)
                     /locus_tag="VQ664_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669441.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(27087..27647)
                     /locus_tag="VQ664_001052"
                     /pseudo
     CDS             complement(27087..27647)
                     /locus_tag="VQ664_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669441.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(27873..30992)
                     /gene="phtE"
                     /locus_tag="VQ664_001053"
     CDS             complement(27873..30992)
                     /gene="phtE"
                     /locus_tag="VQ664_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HET2789225.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQISQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEKVNSNVAVARSQGRYTTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNMQPSQLSYSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKELSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGTSHEKHEEDGYGFDANRII
                     AEDESGFVMSHGDHNHYFFKKDLTEEQIKAAQKHLEEVKTSHNGLDSLSSHEQDYPSN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     VRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLSETGNSTS
                     NSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTG
                     EAPQGNGENKPSENGKVSTGTVENQPTENKPADSLPEAPNEKPVKPENSTDNGMLNPE
                     GNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVI
                     KKNLSDLIA"
BASE COUNT         8835 a         6360 c         5686 g        10121 t
ORIGIN      
        1 aaaaggatct agtttttatt tttagttaaa ttatgtctat atttttcatt aactcatcaa
       61 taaaaatttg tttgctaata tctctttctt ctgattttgt ttcaaggatt attgctacat
      121 cattcatatt tttaggtaaa taccaaccat ctggcttatc tgaatatccc ttgaagccta
      181 attgattaaa agtagttatt tgaccagtac cttgattgat gttttcttca acttcattaa
      241 agcctatact tctcttgcat aatccctaac ttgatcttct gtccttaaag tcattttcta
      301 ttcctcgtca ctaaaattat cttcaaaact aataatatca ttaggagtgc aagataaagc
      361 cttacatatt ctttctaaat tcttaaatgt aattggttta tcctttccca tttgtgccat
      421 aacatttgtt gtaagtcctg ccatagctat tacatctgtt ttctttagtc ctttttttgc
      481 taactgtatc cataatggtt tatagttaag taccataata tccctctttt tttcttcatt
      541 aaatttattt aattatagca taaatattga tttcattcaa tcttacattg atttagtgat
      601 ttgttttaga gaatttgttg tgttattccg tccttatttt gccataaatt gttttaagtg
      661 ggacctctta tccttaccat ttttacctcc taattttgag tataaaaaag acgatagagt
      721 ttttaatttc tatcgtctga gatttacata ttaaattttc atcacaaaat aagactcttt
      781 aaagaatctt taaattcatt ggtatgctgc ttacaatatc cattattaaa atggatacta
      841 taagcagcac accaactatt tattttttga gttttaaact ttggtagaag tcttgaactc
      901 cttatattta cataactatt tgcctctata actattatga cacgaaacca acaagcaagt
      961 tcaagcatct ccatatcttt attcaaatga ggactaagat attcacaaac tttatcataa
     1021 acctctttat cttttttcat aaaaggggca tacaacttag caaatttatc ctaaaatttt
     1081 ttgttgcctt tatcaatcat ttcaacgctc ctttaaatat aaaaataatc ctatcaatct
     1141 ttatattgag cctattttct aattgatacc ttgcaagaaa ggaataatag ctgttcctat
     1201 accaagtagg aatgtaataa atgcagaaag tcatatactg tcattctttt ctattaaatc
     1261 attttgaagt gtctcaaagc atccatgatg gcttcttctt tttcaggtgt acactgtgga
     1321 ataatttgtt tatccttttt agacttgttg taatgttctc gtaattctat tccacatttc
     1381 ttttttatct gtgcaatata taatgtcgaa acttttaatt caaatttatt ccaaacatat
     1441 tctttgattt gagcatatgt tgctttgctc tccgcacttg tcaaatccat ctcatccagc
     1501 tcaatttcaa cacttatgtg cttatcgaca tcgagtttgg acaaaagtgc taccgtctcg
     1561 acgtgatgcg tttgaggaaa tagatccacc ggctggactt tcttcaattc atatcccaat
     1621 tcttggtaga gtttgatatc acgcgccatg gttgcgacat tgcaggagat ataggcgatg
     1681 cgatcggctc ctgtttgggc gcttgctttg ataaagcttt ctgtcaagcc cttgcgtgga
     1741 ggatcaacca agataacggt tggttgaata ccttccttga gccatttctt catggcattt
     1801 tcagccgtgt cacagacata gtgggcatta gtaatcttgt tcaaagaagc attcttctgg
     1861 ctattctcaa ccgcttctgg aatcagttca acaccgtaga cttctttgac atgcttggcg
     1921 actgataaac caatggttcc aataccagaa taagcatcaa taaccacgtc atcttttttt
     1981 aactctgcaa agtcaatggc tgtttgatag agtttctccg ccatttcagt attgacttgg
     2041 taaaaggctg ggccagcgat ttggaagtca tttcccaaca tctggtccgt aatatagtct
     2101 tgaccataaa gagtgcacca ctccttacca aaaatcgcat tggtattctg gtcgttgata
     2161 ttttgcatga cagacacaat ctctgggaac tgcttgataa cttgttcaat caattggtca
     2221 acacgaaaaa cttttggacg agttgtcacc aaaacgacca tgatttgtcc tgaatagtga
     2281 ccacgacgca ccacaagatt ccgaatcaat ccagactgtt ccttttcgtc ataaggtttt
     2341 aaatcaaaac gacggagcag gtctcgaaga gctactacga cttggtcaat gacaggatcc
     2401 tggataaaga aatcttcaag gggcatgagg ttgtgcgaat tcttacggaa aaatcctgtt
     2461 tccaagacac cattcactcg acgaacgggc acctgcgcct tattgcgata cttgactgga
     2521 tgttccatac caagcgtttc agcaacttct acatctgcaa ttccagcaat cttgtagaga
     2581 ctgtccttga cttgcttggt tttaaacttg agctgttctg gataagaaag gtgtcctaaa
     2641 tccgcgattc ctgaacgcag gtaagccaaa tctagatctt gattacggtg tagtgactgg
     2701 acaaggtatt tttcaacttt tccaaagcca atctttttat tgaccttgag gacacgcatg
     2761 agaatttttt cactcggtaa agcattctct acaaaaaaga ccaaaccatc taccttggca
     2821 actcctgccc cttcatgggt caaatcaaca atttcaactt ctacaatatc atttttcttt
     2881 aacattcttt tctctttcta ttggccgaca aaaaagacgg caacgttacg attaccatcc
     2941 attataccat gaaatttctt aagaaccaaa actcttgaag aagttgacaa gggcttgcca
     3001 gagggagctt aagaagttac caccgtcctc tagcgcctta tccgcatcaa agttaaggtt
     3061 gatattttta aaactgtcgc cagcttgtga tacgatgctt tgtttaaggt catttagggt
     3121 tttagtgaaa tctgcattgc tgaggatatc actctttgag agattcaagg caaaattgat
     3181 gatgatattg atctggtttc ctgttatgac ctgatcaagt ttgtaatttt ttaaggtatc
     3241 ttcaacaatc ttgcggacat cttcttctgt cagatttccc ttgctttctt tagctttggc
     3301 gagtcctgac ttgatatcag ctagggcaac gtttaattta ttagcatcat agcctgattt
     3361 gtccttgttt tcagcattga tatctgacaa agcctttagc tcttcttgag ccaaatcttt
     3421 attggcttgc ggcaccttgg ctccattagc ttctagcgaa tagtagatcc cagccaaagc
     3481 actctcacct gtaactggaa taggggctgc tacagtgatt ttggcatgtt ccatacccag
     3541 cgttactgct gcgtttcggt acatatcctg agtcacctta gtgatatttt ctggtgtttc
     3601 aatcttgacc tcaagtggcg atttgtcacc tagcttttga atcttggctg atgaatacaa
     3661 ctgtaagcta gagtcattgg ccacattcat gattttagaa taaacatcag gtgtcatggt
     3721 cttgagttct ttggtatctg ttgaggcatt gtagcccagt tttttaagag tttgattttt
     3781 ttggtcttca gatagggagg aacctaggac atattcaggt tggacatagg tttcatcgat
     3841 aaccttttga acatctgttg ctgcatggac gctattcata gctgttactg cccacaagac
     3901 cgcagcactg gtcagaaaga gtttctttct catagggaat ttcctccttt acttttctag
     3961 agtaatatat ctatcttaaa gaaaacttat aacaaaaaca cctggtctag ccagatgttg
     4021 aaaagagagt gaaacatttg atgatgtaaa ggttaagtcg tacctgtcta gaataataat
     4081 agtttcctcc atttacatag agttcagcac cgtgaaaaat ggaaatgggg tgaatataac
     4141 tataagtctt tccagtcgta ttaccaagca agggggcaac agtctcacga gagtactgtt
     4201 tggctagagc caaggtattt tccttgccat tttgggcgat aaaatcgata taggcaggtc
     4261 caaaattata ggcttgaaca gctgtccaga tatctacccc cttcttctgc gccagataga
     4321 gattgcctgt cagagtttga atgccttgcc gaatgctaga ggcattatca ttgatggtgt
     4381 tggttgaacc acttgcagac tcactagact gcataacatc gccttctttt ccttttgttt
     4441 cagtataaat catagcaagc acaagctctt cgtttgctgg ggtgtctttt tcactcaaga
     4501 tttctcgcac catgggttga taggtcatga cttgtttgac atcttgatga acgcggtaag
     4561 ctttatagcc agcaaaaagg aagactgcta gtacaagcac tcttcgaatt cgtttaaaca
     4621 ttatttactt tggatatcct cgatattttt gattaagata gagtaggttc cattttcctt
     4681 ttggataaac tcaacagact cggcgtcttg atagacgtta ttgggaacga tgagctcaat
     4741 tccatttgat aaggagagtt tttggttttc aaatttcttt aattggcgac tggcatcaat
     4801 ttcatcaaat tgaacaggtt ctggtacggc ttctttgact tggtcaataa agctcaaacg
     4861 agccgtcaga ttgttgtcaa aaaggtcatt agccaatttc tcaggtgaca attcattgct
     4921 ttcttctagg ttgttgaaaa tcgctgattt gaccttggat tgaaattgaa aatcatctgt
     4981 gttaaaagat tcagcaattc tctgggctgt tttttccagt tccttgatag attttttagg
     5041 agaaatctta ggagcgacag caagaagatt atctgaaaaa tagttcaaaa aagtcccgtt
     5101 gtacttgatt cgtttttcaa tcaggtgata cttgcgactc tgaagattga ccaccaaggc
     5161 ctcgtcagca cccgttccaa atccaggcag gttattctga gtcagcttga ttggattatc
     5221 aacttctcct ccgaggtggg tcaaggtctc ccgcagggca attcgcaaga aagcgaaatg
     5281 ttctacacct tctttagaaa attgaacaaa aatcaagtca ttggtcttga gattttcaga
     5341 aatgctaaac tcctctttcc agagattagc cagcgttact gatgtctcca acaaatcgtc
     5401 tgtaatatga ttgaagaagg gattttcttc ttcgaaaatc ccagtcttgg cttcatctga
     5461 atacacatgt tcaatttttt tacgtaggta ttcttcgatt tttggagtaa tattgagaaa
     5521 cttatctgct aagaacagct cggtatcatc cggactgaac tggtgaataa tggctttctt
     5581 aatataaatg tccataaaag ttttattcct cgtataatgg gaaggcatct gtcaattctt
     5641 tgactgcact tctcacttct tctaatacag cctcattttc tgaattctta agggttttaa
     5701 tgatgagttc agccactttg cgactttctt cttcaccaaa tccacgtgca gtaatagctg
     5761 ctgctccgat acgaatccca cttgtcttga atggtgacaa ggtttcgtaa gggattgaat
     5821 ttttatttag ggtaatattg acttcatcca gcaagttttg agcaactttt ccgttttcta
     5881 caaccttagt cacatcaaca aggaagagat ggttttcagt tccacctgaa ataatacgga
     5941 aatcagggtc ttgcaagaag acatctgcca tagccttgct gttcttaatt acattggcag
     6001 catattcctt gaaggctgga tccaaaactt ctttgaagga aactgcctta gccgccacaa
     6061 catgctctaa aggaccgccc tgaatacctg ggaaaatagc tgaattgatt tttttagcaa
     6121 gttcttcgtc attggtcaaa atcaaaccac cacgaggtcc acgaagggtt ttgtgggtcg
     6181 ttgttgtagt gatatgagcg tatggcactg ggcttgggtg aagaccagct gcaaccaagc
     6241 cagcgatgtg ggccatatca accataagct tcgcaccgac agcatctgcg atttcacgga
     6301 attttgaaaa gtcaataatt tgagaatagg ctgaagcacc agctacaatc agttttggtt
     6361 ttacttcttg ggcttgtttc aagatagcat caaagtctaa gagttccgtt tcaggatcaa
     6421 cactataaga aacaaagttg taggtttgac cagagaagct aacaggagcc ccatgagtca
     6481 aatgaccacc tgatgccaaa tccattccca taaccgtatc acctggctca atcaaggaca
     6541 tgtaagccgc acagttggcc tgacttcctg agtgaggttg gacattggca aatttagcac
     6601 cgaaaatttc ttttgcgcgt tcaatagcaa gagtctctac aacgtctact acatcagttc
     6661 caccataata acggcgtcct gggtaaccct cggcatattt atttgtcaag atagaccctt
     6721 gagctgccat aacagccttg gaaactacgt tttccgaagc aattaactcg atattatttt
     6781 gttggcgttc ttcttctttg gcaatagcat tccagagatc agcatcatat gctttaaaat
     6841 catctttgtc aaaaatcata ggtcttctcc tttattgtgt gactagtcca ttagtttgat
     6901 tttacaataa gaaaatcaaa ctaaaagatg cgaataaacc gtttctgcat tttatcacaa
     6961 gtatagccaa ctttttcata aaatgcatga gcacccagac gatgattggc agaatttaag
     7021 cggataaacc cataaccaca tcttttggct tcttgttcca acccttgtag taaactttta
     7081 ccgatacctt gaccttgcgc ttgaggtgaa actgctaaag ctaagatatt aaatcctgct
     7141 ttggaataga gtgattcgta aacttcagcg tggacatatc caagtaagac atgattagct
     7201 gcatcctcat agccaagtag gaaatgatgg gaatcctgag acagtctagc tagttggcta
     7261 gccgtttcct ctggactaaa agtataaccc aaagcctctt ggttgatgtc acatatcgct
     7321 ttcacatctg tttcttgcaa atctcttagc atttcaagcc tcctcaaaag aaatctctgg
     7381 caaccgagca agaatatctt ctcgtttaat tgcgccttgg cgtaagattt tcaccttgtc
     7441 tccagacaaa tccacaatag ttgaatcctg tccagttaga aaagcatcgt cttccagacc
     7501 cagaacctct tggtcaaaat ccttcagaat ttgttcaaag gttacaccac ttgcctgacc
     7561 tgagatattg gcagacggcc caatcaaggg acctgtctct cgaattaaat ccagtgtgat
     7621 agggtgactg ggcatccgaa atccaatagt tgcaaggtca gaatttaccc aatagggaac
     7681 tcggtcattg gcttcgagaa taatggtcaa gggacctggc aaaaaggtct ctacaagttt
     7741 ttgtagataa gttggctgat tcttagaaaa gtgcaagata tcctcgaaag aggcgatatt
     7801 gagattgagt gccttatctc taggacgacg tttgagttgg taaacatggt caactgcttt
     7861 ttcatctaag gccttggcaa aaagaccata aacagtctct gtaggtagaa cgacagctcc
     7921 accattttcc aactcttgtc taatcctgtc catcatcaac cacaaccatc ctattttgac
     7981 caaattggtc tttgagtgtt cgaacttttt tttcaggaag atgttttcta aaaagttcgg
     8041 gaacactttg accttgcttg tatccaattt caaggtaaat cttaccacca tccttgagat
     8101 agtcttttgc atcttccgca attctacagt aaatagctag gccatcctcg tctgcaaaga
     8161 gagctagatg aggctccgaa tgcaaaacat tcaagcctac ctctgactca tcttcacgag
     8221 agatataggg tggattggat acaattatat catatttttc agaaatttct gcaaaacaat
     8281 cagatttttt aaaaaatata ttaagatttt gatcgctagc attctctgat gcaagctcta
     8341 aggcctcttg agaaacatct gctgctgtca ctgaccaatc tggtctattt tttgctagag
     8401 cgagagcaat agctccacta cctgttccaa tatccagaac tgagagattc gtctcaagat
     8461 tttcagttag aataagctcc actaactcct ctgtttctgg acgaggaatc aaaacccgtt
     8521 catccacctt taaatgcatt ccataaaaat ctgcctgtcc aatgatgtac tgagctggct
     8581 tgtgagctgc tagttgctgg taaatatctt ctacaaattg tttttcttcc tctgttgtca
     8641 cctcctgctg gagggcaaaa ataaagtctg taaaagatag atttttcaga ctacgataga
     8701 caaaagagag gctttccgct tcctctcctt gtcttatcaa ctcttcttca aaatttgaaa
     8761 ataattgagc taatttcatt atttgtttaa ttcttctagt ttttgtgttt ggtcataaag
     8821 caccaaggca tccacaactt cgtccaattt accagacaaa atcgtatcta gtttttggag
     8881 ggtcaagccg atacggtggt ctgtgacacg gttttgaggg aagttataag ttcggatccg
     8941 ttctgaacgg tcaccagtac cgattgtcga cttacgctca gcgtcttgtt catcctgagc
     9001 aatctgagca aagtggtcag cgacgcgtgc acggataatc ttcatagcct tctcacggtt
     9061 cttctgctgg gtacgttctt cctgcatctc aaccttgata ttggttggca agtgaacgat
     9121 acgaacggca gtcgcaacct tattgacgtt ctgtccacca gcacctgatg cgtggtaaat
     9181 atcaacacga agatcttttg gatcgatatc gtattctact tcttcgactt caggcatgac
     9241 aagaactgtg gcagttgagg tatgaacacg accttggctt tctgtcacgg ggacacgctg
     9301 cacacggtgg gcacctgatt cgtacttaag cttagagtat acagactgac ctgaaaccat
     9361 agcaaccact tctttaaacc caccgacacc attcatagag gcttccatga cttcaaagcg
     9421 ccagccttgg gcttccgcat acttttggta catagttagc aaatctccag cgaaaagtgc
     9481 cgcttcgtct ccaccagctg ctccacggat ttcaaggatg atattcttgt catcgtttgg
     9541 atcctttgga aggagcaaaa ttttcagttt ttcttcatat tcttcttttt cagccttggc
     9601 atctttgagt tcttgcttgg ccatttcttc caagtccgca tctccgcctg attccttaat
     9661 catctcttcg gcatcgacga tattttgaag gacttgttta tactcacggt aggctattac
     9721 ggtatcacga ttggaagctt cttcttttga aagctccata aaacgcttgg tgtctgaaac
     9781 gacatcaggg tcactcagca attctcctag ttcttcataa cggtcttcta cagcttgtag
     9841 ttgatcatag atgttcattt ttcttcattc tccttattga tttcaggggc aaaataatgt
     9901 ttacggcaaa ccgagatata ggtttcatta ccaccaattt ggatctgttc tccatcgtaa
     9961 acgggcagtc catcctgtgt tcgcaacacc atggtcgcct ttttcttgca atactgacag
    10021 atggtcttga tttcgtcaat cttgtctgct aaaagcaaga gatatttgga accttcgaac
    10081 aattcattgc gaaagtcatt tttcaagcca aaagccatga cgggtatgtc taactcgtcc
    10141 acaacacgag ctaggtcata aacatggtgg cgtttgagaa actgggcttc atcgaccaac
    10201 acacagtaag gtttttctgg taggcctcgg atatagccaa agatatccgt tgtttcctca
    10261 atcgcaaggg cagggcgttt catgccaatt cgactcgaca catagccaac accgtcacgc
    10321 gtatccagag ctgaagtcat aatcacaaca ccttttcctt gctcctcata gttataggcc
    10381 accttgagaa tctcgattgt ctttccagag ttcatggtcc cataacgata atacaactgt
    10441 gccatgtttc ttgcttcacg tccatttcta aatttttgct acattctagt atatcataat
    10501 tttcttaagc tttaaacggc aaaatgtggt aaaatggaag aaatcaaaac tagtggagga
    10561 agctattatg ccatttgtac gcatcgattt atttgaagga cgcacgctcg agcaaaagaa
    10621 agctcttgct aaggaagtaa cggaagcagt tgtccgcaac actggagccc ctcaatctgc
    10681 tgtccatgtc atcatcaacg acatgccaga aggaacttac ttcccacaag gggaaatgcg
    10741 tactaaataa gctagcttaa gcagaattgc ttaggctttt tcaatctcca agtagcattc
    10801 attgaagaaa tatcctaaat ttgttacaat ttgaaaagaa acttggagaa tttccaagaa
    10861 aagagctatt aattaaagga aacattatga ttacacgtga atttgatacc atcgctgcta
    10921 tctctactcc actaggtgaa ggggctattg gtattgtccg cctgagcgga acagacagtt
    10981 ttgctattgc gcaaaagatt tttaaaggaa aagacttgaa caaggttgcc agccacactc
    11041 tcaactacgg tcacattatt gatcctctga ctggtaaagt catggacgag gttatggttg
    11101 gggctatgaa gtctccaaag accttcactc gtgaggatat tatcgagatt aacacccacg
    11161 gtggtattgc ggtgaccaat gagattctcc agctagctat ccgtgaagga gctcggttgg
    11221 cagaacctgg tgaatttacc aaacgtgcct ttttaaacgg tcgcgtagat ttgacacagg
    11281 ccgaggcggt gatggatatc atccgcgcca agacagacaa ggccatgaac atcgcggtca
    11341 aacaacttga tggttccctt tctgatctta tcaataatat ccgtcaagaa atccttaaca
    11401 cacttgccca agttgaggtc aatatcgact atcctgagta tgacgatgtt gaggaagcca
    11461 ctactgctgt tgtccgagag aagacaatgg agtttgagca attactaacc aagctcctta
    11521 ggacagcacg tcgtggtaaa atccttcgtg aaggaatttc aacggctatc attggacgtc
    11581 ccaacgttgg gaaatcaagc cttctcaaca acctcttgcg tgaggacaag gctatcgtaa
    11641 ccgatatcgc tgggacaaca cgagatgtca tcgaagagta cgtcaacatc aatggtgtac
    11701 ctctcaaatt gattgataca gctggtattc gtgaaacgga tgatatagtg gaacaaatcg
    11761 gtgttgagcg ttcgaaaaaa gccctcaagg aagccaactt ggttctacta gtgctaaatg
    11821 ccagtgaacc actgactgcg caagacagac aacttcttga aattagccaa gataccaatc
    11881 gcattattct acttaataaa accgacctgc cagaaacgat tgaaacttcg aaactacctg
    11941 aagacgttat ccgtatttca gtccttaaaa accaaaacat cgacaagatt gaagagcgaa
    12001 tcaacaacct cttctttgaa aatgctggct tgattgagca agatgctact tacttgtcaa
    12061 acgcccgtca catttccctg attgaaaaag cagttgaaag cctacaagcc gttaatcaag
    12121 gtcttgagct ggggatgcca gttgatttgc ttcaagttga cttgactcgt acttgggaaa
    12181 tcctcggaga aatcactggg gatgctgctc cagatgaact catcacccaa ctctttagcc
    12241 aattctgttt aggaaaataa gaaaaatcca tgatccttca ttcggtcatg gattttattg
    12301 tctttattag taatctggtc ttaagacccc tgttacagtt gccttagttg cttcgtagtc
    12361 gccatctacg acaaccttga taatgcgttt ggcatcttct tctggtgctg gaacaagagg
    12421 tagacgagtg ggtccagctt caaatcccat atagttaaga attgccttaa ctggagcagg
    12481 acttggataa gagaagagag cattaacctt aggaatgaat ttacgctgaa ttgctgcggc
    12541 tttcttcata tcgctttctg caatggcagt aaacatctcg tgcatttcat ccccatttgt
    12601 atgagaggca acagaaataa ccccatccgc cccaaggttc atggcatgga aagcatctcc
    12661 atcctcacct gtataaatca agaactcttc aggcttgtgc tcaatcaagt aagccatatt
    12721 agccaagcta gtacattctt tgacaccgat aatatttgga tggtcagcca agcgaagcat
    12781 ggtttctgga gtcaattcga caactacacg ccctggaatg ttatagataa taattggtag
    12841 gtcagaagca tctgcaatag tcttaaagtg ctgatacatc ccttcttgag aaggtttgtt
    12901 gtagtaagga acaatagcaa gcccagctgc gaaaccacca aattccgcta cttctttgac
    12961 aaactcaata gagtcacgcg tatcattagt acctacaccc gcaatcaaag gaacgcgtcc
    13021 attgacaacc ttttgtacag ccgcaaacaa ctccaactcc tcatcgtggg tcaaagttgg
    13081 actctcagca gtcgttcctg cgagaagaat tccatccgta tgatgggcca ataaatgctc
    13141 aatcaaggct ggaatagcat caaagttaat agaaccatcc tcatgaaagg gggtaataaa
    13201 ggctgtaatg attttacatt cttttaaatc ttgataagac atgaaaacac ctctctattt
    13261 caaagaagga gttcatctga actcctaaac gatatgacta ttttaattca aatttcaatt
    13321 cggctgttgg acgaaccaat ccacgttcat gaagagtttc agcaatctga actgagttcc
    13381 aagcagcacc tttgagaagg ttatctgaaa caacccacat gtgaattcct ttttctgcat
    13441 ccaagtcttt acggatacga ccaacaaagg tatcacgcga accaactgca ttgatagctt
    13501 gaggatagat ttgatgagct acatcatctt caagaacagc acctgggaag gctgcgatag
    13561 ctgcttttac ttcttcgatt ggagccactt cttttgtttc gatataaaca gactcagagt
    13621 gagctgacaa gactggaata cgcacacatg ttgcagatac tgcaatgcta tcatcttcca
    13681 taattttctt agtttccttg gtcatcttca tctcttcgta cgtgtaatca ttatcagtga
    13741 aaacatcaat ttgtggaaga gcgttaaagg cgataggata atgtttcttg tcaccacctg
    13801 aaggcaaaat ttccgcatgc aaatcacatg gtttcacacc atcattcaag acttcacgaa
    13861 gttcacgttg tgtctcaaga attgctccca taccagcacc tgaaacggct tgataagttg
    13921 aaacaatgat acggtccaag ccccattttt ggcgaaccgg ctcaagagcc accatcattt
    13981 ggattgttga acaattaggg caggcaatga ttccgttgtg ggcatcaagt gcatgagcat
    14041 tgacctctgg aacaaccaaa ggaacatctg gattttgacg gaaataagat gtattatcca
    14101 ctactaccac gccagctttt actgcgtatg gtgcatactt agctgatgta gaactacctg
    14161 ctgaaaagag agcaatatca actccttcaa aagctgtttc agtcgtttct tcaattgtaa
    14221 tatcttgatc tttaaatttc aatgacttac ctgctgaacg tgcagaagca aggtaacgga
    14281 ttttatcgat tggaagtgtt gattcttcca acatttttat catctgagca ccgacagcac
    14341 ctgtcgcgcc gactacagca actgtatatc ccataaataa cctctttcgg aattttctaa
    14401 aaatttctat aatagaagta ttatactact ttttccatga attgcaaagc tttttcatca
    14461 ttttttggaa aataaaaatc ccagtcgcta gactagggac taagaggcat cttcatgtga
    14521 tgagcaggtt cacacaactc atcaaggtcc gctcctgcgt tatgacctcc ttatgctcaa
    14581 tagtagtccg aagactacct atcgactcat cgcatattct atattactag agatacttga
    14641 ttttgtcaat aagaaatttt ttcgatcgag tataacaaaa aactctcgta ttcaagagtt
    14701 tccctataca tatcatgcta attgccggga tcgaaccggc gacctcatcc ttaccatgga
    14761 tgcgctctgc caactgagct aaatcagctt acttaagaag tatactatat tcagaaaaac
    14821 ttgtcaagtt tccttagaaa ttttccatag gaaaaagcca ggtaagaact acctagctta
    14881 tcttcttcta tttacttaaa tcaattcgac gaccaatttt accaataata atcgccccaa
    14941 taatcaatga agcaaattca ccgattcctg ttgtaaacca agtaaggaag aatggtaatt
    15001 ctgctacaat atttaactct gcagcgatag taaacatgga aattgaaaag aggattgaaa
    15061 agaagaaatg atcttttcga atcaatccgt taaagaggta atccttgcta tattttgcaa
    15121 aaagccaaac acctaaactg aggaatacta aggttgaacc accaccaaca aagacatcta
    15181 gcagtccgaa gctaaagaaa ttagcaatca tacaaccgat ggtaactccg atgatgtact
    15241 taggattgta aaaagccata aagttcatca tttctgaaat acgaaactga taagcaccat
    15301 agctgatggc atttaggggc ggtgtgacag tcaaaacgac gtagatagca gcgacgattg
    15361 caatatctgc aatatcacga atagttaatt ttttcatctt ttctcctttg gcggttgccc
    15421 gcgtgtaata tgcttggtga aagaagctaa gcaccaaggg ttgctttatt caaccctact
    15481 agtatagcac aatagcctgc tttatgctat acttaacaca tgaaaattcc tattcaaaaa
    15541 ttttttaaca atgaaatctt agcctatctc ttttttggcc ttgcgacaac tctagtttcg
    15601 attctctcac gactagtcat ttatcaacta agtcatcagg aactcctggc tactgcccta
    15661 gcaaatatta tcggtatcct atttgccttt atcacaaatg atacgattgt atttaagcaa
    15721 aaaaagaaaa atagacttat ccgtttagtg aaattttctc ttgctcgcct ttctactttt
    15781 ctgttagact tgtttttaac ttttctcttt gtaacccaat ttcctcacat tatagggcaa
    15841 ttcgtaactg aaaacattga taagataaat gctattgaaa caataattgc acaaatattc
    15901 attattatca tcaattatat attgagcaag gcctatattt ttagaaaata atgctccatt
    15961 tatgagcctt ttaattgcct tctataatga tttaggatac aatgaaacac gaaacattga
    16021 aaggaaaaca gtatgttaaa aaatctaaaa tcgttcttgc ttcgaggaaa tgttattgac
    16081 cttgctgtcg gtgttgtaat tgcctctgct tttggtgcta tcgttacttc acttgtaaac
    16141 gacattatca ctcctcttat tttaaatccc gctttgaaag ctgctaaagt tgaacgtatc
    16201 gctcaacttt cttggcatgg agtcggctat ggtaacttct taagtgctat tatcaatttt
    16261 atctttgtgg gtaccgccct cttctttatt atcaagggca ttgaaaaagc acagaaactg
    16321 actggcataa agaaagaaaa aactgccgaa aaaaaaccaa ccgaattgga agtccttcaa
    16381 gaaataaaag ctctccttga gaaaaaataa tcgattaaaa ggatctagcg caaagctaaa
    16441 tccttttttc tttactcttt gggtaacttg cctgcttttt caagcatttt tttgatcaga
    16501 taaggcatct taacattctc ccgccctttt ttctcaatca gttttttcac aaattctggc
    16561 atttgtaaat cttcagattc agctaaaatg tttttcgtct cgtctgaagg aactaactca
    16621 tcaaaggtct cttcttctgg gagaaattcc ttaaactctt gattttcatt gactctaact
    16681 gtattgacca aagcatcaat caaacgagaa tctgtatttg gcattggtgg acgatggtag
    16741 tttaccccaa attcctggca taagtcataa cattctacat cattgtcaaa caagacctca
    16801 atatgctcac tgatgaaact aataggtaca aaaatataat ggtctggatg ttctgtctgt
    16861 tctctgagat actccaaaac atctggttta atccatggaa taccaatatc actctcactc
    16921 tgccaagtgt tggtatattg ttctgaactc aagcccagtt tttcagcgac tagcttgcta
    16981 ttttcgaaaa tttggtctat ataaggatca ccaaagtcca aggcaaaaat gggcacacta
    17041 tgggctgaaa agatgacttt aaagctgtct tgctttactt cttcttttaa aatcttagca
    17101 atttcatctg cccaatagtt taagagcact tcttcctgat accagtcctt aatgaccaaa
    17161 aattgaattt gtttgctttc taaaaatttt tcatagccca tgacagagta gaaagaataa
    17221 tggggctcca aaatcaagca gatacattct tcaacaccat cagtttccat ctgcttgatc
    17281 acgtctggaa taaagggacg agaaaatttg ttggcaaagt agataccgta ctcctcccct
    17341 aaacgttctt tgactaaatt gacctcctca cgtgtaatcc gctgcaaagg cgtcccaccg
    17401 atacgaatat agttgtcata gagagtctgg atttcgtggt cttggggtct aactccacga
    17461 cgaatgtttg taaagaattc tgctactcct tcaaaactaa tctcctctgg agatccaaag
    17521 gtcatcatta atatggcttt tttcatgtta tcatccttat gatattattt tctctatcca
    17581 ttctatcatg aaagaaaaaa atagtaaacg tttcctacgt ctactatttc ttttgctctt
    17641 ttgttttttt atctcgtctt ataattagga tgataaggac aagaagtaag aggacgataa
    17701 taaggagtag aaaggctaga atgtaaatcc aatgactggg aattccgtga tcgaaatacc
    17761 gtgttcctac tgcttcccca ctttcatcct gtgctacttt caccggtgca tccgttattt
    17821 tagctaaaag gatatgtcgt ccattagtta tgttaaggaa acatctcgct tgtacttggc
    17881 tttacttagc agatattgat agtaagcctg gtgttcctca tccttggaac tcaaggttcg
    17941 ataaatctcc gtgtcatagg catccacttc taaaatccca aaaatttcaa gaccacgttc
    18001 tcgaccattg tagtagatag aaccgtagcg atgctggtcg aagaattcct tatcagcaaa
    18061 tttcttaatc tcaccgaaca tagcccctga agccatagag tgtccgtaga tgatcgtatt
    18121 aaaatcagta aagttgggat taaagcgata gtcgagaaaa attgatccca ttatcgtata
    18181 atcgccaaag gcattgcggt caaggtattt gacattatcc tgactttgta gaagcggata
    18241 gtctaccttg gtcccatcaa ggctaatcca accgcaaaca tctttgttca agtgctgtag
    18301 ggtttcaaaa cctgtgctcg aagcatcctt ttcaatagga ttatagtgat catagtcact
    18361 tgcttctact actctctgcc aactaaaaag agctacaaaa acacagaaga ataccagaaa
    18421 tacgttttta aatcgcgctc ttttttgaac cgtcatcagc actcctttct atgcgagatt
    18481 tcttaaaagg aaaggaggcg ggacaaaacc gcctcttttc tattcaccct tagtcagtaa
    18541 aagggtctgc ttcttgcatt ttttttactc tctcttctac gacgtaggat caagtagagg
    18601 acaaggagta agaaaatcaa gagcaagaac aatacaaaca agataaggta ccaaatccat
    18661 agtgggattg atgagaggaa acgtccaaga gacgagtcat caaagacact gtatggaaat
    18721 ggttttgatt tttttgtatg gaaagtattt ttagggacgg tgtctgtaat ctttgcgact
    18781 acgatatgac gaccattggt cacatcgaga aaacaggtac tgagtaggat gatacgatca
    18841 ctcggtgaga gtgagatatc ccgcttgtgc atggcgactg agagcaggtg gtctagatag
    18901 gcctgctggc ggtcctcacc ctgtattcct ggatcataga tgttaaagtc ataggcatca
    18961 acctccaaca tctcaaagat ctcgagccct ttttccacac cattgtagta tatactaccg
    19021 taacgatgct ggtcaaaaaa ttcctgatca gcaaacttag ccacatcacc aaacatgacc
    19081 ccattttcta cgtggtgccc gtagataatg gtattaaagt cttcgaactt aggattattt
    19141 cgtgcatcga gaaagatagc gcctgtcgct gcaaactcac ctttggagtc cttgttgaga
    19201 tacttttcat tgtccttggc ttggactaag ggatagtcga tattggtgcc atagacattg
    19261 atccaaccga ggacttcggg attgagttct tggagtttgc tgaagcctga aaaactggcc
    19321 agctcatcct gttgcgtcgt gacaggtcga taagcttcgt actcacttga cgaagctaag
    19381 gagtagactt ggttggaatc ccaaagggcg tagaaaccaa agagaaagat caaagctgca
    19441 aaaatgagca gcaagtgatt gatcacccca tccacagcaa gaacgagacg cctagacaga
    19501 ctcttttttg gtttctcacg cttggttttc atcatctgcc cccagccgtt taggcttctc
    19561 tacgtttttt agacaagaca acaaatccag ccaaaccaag accaatcatc aaaatgaatg
    19621 gaaggttatc aatcaagaga ccagtaggag taacgtcgtc gattttgtta gtaactttgt
    19681 tgtcgttttt cttttcacct atgaggatat ctgttaatgt aaaatctaca tttttttgtc
    19741 cttgagatgt ttgttctgca ccatttgtag tataaattga tgaatctgta taacctgcta
    19801 ctccagtttc agttactgta tatttagaac ctgctggtag ttgttcaact gtaaatgttt
    19861 caccatcttt aagagtaaaa ttgtactcaa ctgtatctgc tggggtcact actgccaaca
    19921 cctctgactt agatccatgt tttactataa tattcgtaac aggggtttct gctgttttat
    19981 ttgtacttgg aagttgaatc ttgatatgga attggaaatc tcttgtttta tcccctgaag
    20041 ctccatcaac ttttttagta attgttaatg ctttcgcatt ggggtctact tgactcggat
    20101 catcaggatt aggctcctta cttgcgtctt tggtatatgt gttatcaaat aaattataaa
    20161 cgccttgttc acttggttct actttagggg cgttagattt attattttcc ttaaagtata
    20221 ctgatgaaat atagacacca ccatttactt tattcttaac aataacgtgc atttcatatg
    20281 tacgtttgtc gtatctcatg gcatcaattg ttttaccatt tttggtaatc gcctgccatc
    20341 cagtttttgc ttccgctaca tcataaacgt attcaccagc atggccataa gcaactcccg
    20401 aaaaaatgtc ttctgttgct ttttgaatct tatcagcagt tgggtgatca tttttattgt
    20461 attctacatt tctatctgga attgcaactc cggtttgata tggcgcaccg ttagaagatt
    20521 gtcctgtttt ttctgtaaac ttaaatgtaa atgtcgctgt tggtgttgtt attccctctg
    20581 caatattcaa cgttttatta atcttcacaa cagcattatt ttcaccattt gctttggtta
    20641 ttgctgaatt atcatccgca aaagtcggga cacctctgaa tacggacaaa gcggttatag
    20701 ctgcaatgct tgcagtgaat agctttttaa agaatgtttt tttcatgatt atttcttttg
    20761 tttttttatt ttcttttttc attatgatca tcaaaagcct cgtcttctaa tgactgttac
    20821 aactttgcct tgagtatcct gtatagggat ggttccaaaa gcacgactgt ctacagccgt
    20881 tgttcgattg tccccgagga caaaaagttg tcctgctggg actttcatcg ggaaggttgc
    20941 cccttcctta tagagcagcg tttctttgta gatatcttgc tcttgttgag gagaaccgtt
    21001 gatgatgaga ccattttcgt ttatatcgat tgtacttcct tcggttgcta tgacacgcgc
    21061 cactctttcc ttacctttat aactatagac tagcaaatca ccaatcgaat agcgtttatc
    21121 caacctataa tagacgacca agtcgccatc ttttaaggcg ggcttcatgc catcgtcatt
    21181 gtatcttaat aatccaaaga cgaaaaagta aaggatggct agtacaaatc caaccatcag
    21241 aagtttactg actaagtaaa ggatatctcc ccagacactc ggcggagact tatcccgatt
    21301 gacttgtgtt actggtttct tatgtttctt tttaagcagc atcacttcct cctattcacc
    21361 acaaggtgac caagtaagat gataaagaag atccctccta gaggaagaac gactccaagc
    21421 acgagagtgc tactcaagaa gtcaattccc gtttcaggta cgctgttttt attattcgtg
    21481 actgtcgcag acttatttgc atcaagagtt ccttcttttt tatcatagga cacctgatac
    21541 ccacgagacg aacttgcttc ttcttcgata ctataacgag catttagagg aaggtcgaga
    21601 atcttgatgg ttttatcttt ctttagatca actgtcgcct taccattggt gaattgtagc
    21661 gttgtttttt gattatttac tattgcacta tacgatccat tcaatggttt attttgcgca
    21721 tcctttacgt taatggtaat cttaaaggat tgcagaagat tagcaaaagc acctgtaact
    21781 ttttttgtga ctgaaagtgt cggaagtctg tggttggtga cgattgtttg aacatcctct
    21841 gacaaagtcc cctcttgttt ttcataggtg acatgatatc ccgttctaga gttctctact
    21901 tcttccacct tatagtgggt atcacgaggc agataactga gggcagtttc ctgactattt
    21961 ttgagagaaa tctgtgcttt cccgttagtc actgttgtat tcccaaactt gccgttaatc
    22021 ggcttgccat ccttatctga aaaggtaaca ttaattgtga aagatttatt aggtgattgt
    22081 tcaccttcta ggattttctt tacggtgaga cttggaagct gtcggtaaat aactttgaag
    22141 gatggtttct ctttcgtacc tgtcttttga acttcgactg tgtatcccgg agcgtctggt
    22201 gctttcagtt cgtagtcata tcccttagct acctttgcaa aactagtatt ttcagtaaaa
    22261 ctattcgttt gaactggact agtgaccttt cgataggaat cctttatact tccatctttc
    22321 ttttggttta agtttaattc gacactaggt ggacgatttg ctgatggatt tgattttcca
    22381 tccacacctt tccactcaat ctctacagga accgtcaatg gatctgacgg cttgaaagtg
    22441 ggcttctcag aatagtcttt tattttggta cgtgaggtcc caataccata ggaataggca
    22501 acttttgccc ccttgttgga gtagagttta gtagcatcgg cttcttcggc atcatcacta
    22561 gtaagtgtct tatcacccgc aatcgcatca aatgcctctt ggctagaggt gacagtaaac
    22621 ttgagaacgt acttggcgtc atcctccaaa gtgtaactcg gattaaactt ggctgttact
    22681 tccactaatc cctgttcgtt cttcttagtt tcaatcgtaa cttgattgtc attcagttct
    22741 tgctcgttac catccttgat tttgacgaca cgaaggtgtg aagcatcacc aggtaacagc
    22801 tgcacgtact tggacaagac atctgatata gttacatggt gtacgcctag aggtagaatt
    22861 ttatctgtga tttctttgaa tttttgttgc aagtcatttt cattattggc agaaaatatt
    22921 tcgttgggga ttccagaatt ataaccactg atatatcctt taagagatgt gatactatcg
    22981 tttgaaccta tataatatct gaatttgatt gaataaaagc catctatttt tggagctatt
    23041 aaactagata tattcagcat tcctctttct aaaccagagg taaaccaata tggagtatca
    23101 atcatacgtc ccacatttgg attagaataa tagttatata ttgttctccc actattagac
    23161 tcgtaataca tattagcttc gccatctgac agcagaataa ctactttttt tgccccagcc
    23221 cttgcacttt gcaacaatct ttgagcttca gttaacccag catttatatt tgtcccagtg
    23281 ccaatgcccg cgtccatacc ataagaacga ctagagtcag caattgttaa cgaactaaca
    23341 atattttttg agctattaga atccgtgctc caagatacta aagttttagc atcatcatat
    23401 gaagagatat ttgaatacca accagctcaa tttggccaag ttccatattg ataactcaga
    23461 taatattcat tataataacg gtcattatac tgattatcaa tctttccggc aaaaccaact
    23521 atagacagac ggttttggga attagaaaga attgtatcaa tgagcccctg acgaccattc
    23581 acacctttca gtgtatgttt tagtgcttca atcctactaa tgtatcgtct actagagtaa
    23641 gaccacacat ctcgctcttc catactccct gaaagatcgg caaccaagac tacatccaag
    23701 ggttctgact gggtctccgt tcccagttta gatgtgatat ccagtgacaa ctcatactgg
    23761 tctttttgcc ctgatatcgg agtaatcgtt ttgtgcagag ttgtctgagg ttcagttatt
    23821 gaatctgcac gtaaagaatt aattggtgca cacaaaaaaa gaatagcgag aaagataact
    23881 aaactactgg taaaatattg aatcttctta aaatcatatt gaacgttcat gctatctccc
    23941 ttgctagaat atgttttaat ctgatactat ataaatctga gacttccata agataattgt
    24001 ataataatat taacttcgtg tcaattaatg tgtttgaaaa catgttatta taaattacaa
    24061 aaaagtatga ttcttctttg tttttcaact ttttctgtgg taaaatggaa aaaatagtaa
    24121 aaaatttcat aaaataaaga tgcatatatt tattctaatc gctcgaaaat ttcttttgaa
    24181 agtcttctga atttgaatta ttatattttt tcaaaattca taaaatttct caaatcatat
    24241 ttttccgaag ttttgtattc tattttatga taaaaaagga gtttttttat gacttatcca
    24301 aatctcttgg accgcttctt aacctacgtt aaggtcaaca cgcgctctga tgaacactct
    24361 actactactc caagtacaca gagtcaggtt gacttcgcaa caaatgtcct aattcctgaa
    24421 atgaaacgtg ttggactgca aaatgtttac tatctaccga atggttttgc tattggaacc
    24481 ttgccagcca acgatccgtc tttaacacgt aagattggtt ttatatcgca catggatact
    24541 gctgatttta atgctgaagg agtcaatcca caggtaattg aaaactacga tggtggtgtg
    24601 attgaactag ggaattctgg tttcaaactc gatccagccg acttcaagag tcttgaaaaa
    24661 tatccaagac aaacactcat cacaacagat ggaacaacct tgctaggtgc tgatgacaag
    24721 tcaggaattg ctgaaattat gacagccatt gaatatctaa ctgctcatcc tgaaattaag
    24781 cactgtgaga ttcgtgttgg ttttggtcca gatgaagaaa tcggtgttgg tgccaataaa
    24841 tttgatgcag aagattttga tgtggatttt gcctacactg ttgatggtgg tccactaggt
    24901 gaacttcagt acgagacttt ctcagccgct ggtgctgaat tgcatttcca aggccgtaat
    24961 gtccaccctg gtactgccaa agggcagatg gtcaatgccc ttcagctagc aattgatttt
    25021 cataatcaac ttccagaaaa tgaccgacct gagttaactg aaggttacca aggtttttac
    25081 catctaatgg atgtgacagg tagtgttgag gaggtgcgtg caagctacat cattcgtgat
    25141 tttgaaaaag atgcctttga agcgcgtaaa gcatccatgc aatctatcgc tgataagatg
    25201 aatgaagaac ttgggagcga ccgtgtcact ctcaacttga cagaccagta ctacaatatg
    25261 aaagaagtca ttgaaaaaga tatgactcca attaccattg ctaaagccgt tatggaagat
    25321 ctaggtatca cgcctattat cgaaccaatc cggggtggaa cagacggctc taagatttcc
    25381 tttatgggaa tcccaactcc gaatatcttt gcaggtggcg aaaatatgca cggacgtttt
    25441 gaatacgtta gccttcagac tatggaacgt gcagttgata ccatcattgg catcgtagct
    25501 tataaaggct aaaaagacga ggtggctcag ctacttcgcc tttcttttta ttctactggt
    25561 ttttcttgat ttccagtagt tgtagaagat tctgttgttt cattttctga agttgattca
    25621 gcaggtttag aatctcttgt attgcttggt ttgttttcgt cgctagcagt ttcaatgtta
    25681 gattctgcag ttgcgtttgg ttggttctca gcactggtgt tatcactatt tgcttcagca
    25741 tttcttgctg gacttgtttc ttcacttgcg ctaacttttg actggatttg atgattcaaa
    25801 actagaatag cttttgtcga ttcaagtaaa gctgttttgt ctttactatt agcagaaagt
    25861 tgatctaata atgcatccac cttatcaaag tccgcatcag atccattatt actttctaaa
    25921 taagagtgaa gcgacatgag aatatcgtag agtttttgat agagtacaag tgtctgagaa
    25981 tcttgctcag cattttcctt ttcttgttga agggcgctag cgatacgagt caaaacatct
    26041 tttacctgac tgtttacttc atccaagtct gcatcagcct tgtttgtggc agcttttaga
    26101 ttttctactt cttctgccaa ggattgtctg attccttctt catggatttg ttccaagagt
    26161 tgatttgcct tgttcaaaag actttctact tcttccttgc tatctgtcgc agattattgg
    26221 ttgctatcta ccatgtactc ctaaaacagg agagttataa tccaagatta caaggcctta
    26281 cagaaataag aaatccagat aagacaatgt tcgtccaaga cgctattcgc ttcgcacagc
    26341 agcacggatt caatatgctt taattttaaa gtttaggtgt caagacctct ttttagtgtg
    26401 cccaaaattt agagaagtaa tcaatcaact aacttttatt tttttcaaac tttcagtaaa
    26461 ctgacctaaa gctaactcaa tctgtctttg tagatgcttc tgctatcagc tagaagttga
    26521 tctacttttg ccaagactgc cttctcatca aaagttccag gttgatagtt ggattgcagg
    26581 gatggaatct tgtttttcaa agccgcttca tatcccttag tttgaacctt gatgtagtga
    26641 ttgtggtcgc catgaggaat cacaaaacct tctgaatctt cacttataat tcgattggca
    26701 tcaaaaacca taaccatctt cttcctcatg gtggacatgt agtgacggat tacttaatac
    26761 agaactagaa gaacttccta cctcttccgt gttagagtgt gatgggggat tgttaagaga
    26821 tgacttagga atatagtgat agtgttcccc atgtcttact atataagcat cacctatatc
    26881 tctgacaata tcattagggt taaagacata tgtggctgct aattcacctg ccgacaagtc
    26941 actctcagga atgaaatgat agtgaccacc atgtggtact attagtagat tgaaatagaa
    27001 tatgagcaaa ttgataaggg gattttaaag taatttctaa caatgattta gaaactatga
    27061 tgtgctattc taaattcaac tcactatata taaccatcat cggtagtata acgtccctgt
    27121 aattttgcta cagatacttc tgcactagct cctttatcgt ctttaccatg ttcttgtttt
    27181 tggcgattga tttcatcttt tgttcgtaca ttttctgcat gagcttgatc tttaaggtaa
    27241 acataatact ttccatctac cttaataata tatcctccct taacctaact gacaatatct
    27301 tgatctttcg gctgatagtt gggggctttc attaatggct cttcactaaa gagcgcatca
    27361 aaaggaactt taccattata gtagtgataa tgatcgccat gagaagttac ataaccttga
    27421 tctgtaatct taataacaat ttgttttgct tgaattcctt ctttttgact aacctagtct
    27481 ggagtcaaat tttcagtctt cttagtgtct ttattactgt ttacatatga aacacgattt
    27541 ttatctgtat tggcctgtta gctatgttgg ttcagagcat aaacacacag acttaaggaa
    27601 aggataacaa cagatccagc tgctatatat ttctttttaa atttcataat tacctcattt
    27661 ctataattat ttatatgatg tcttcattat taaatgatta tagaaattaa ttaaccaatt
    27721 aattaactag taaatattcc acctcttttt aagttgtatg tcaagaaatt ttatatatta
    27781 ataataaaat gaaattctcc caaagtcaga gttttatttc taacttttga gagaacttca
    27841 tttttgattc agactttttc tactgctatt ccttacgcta tgagatcaga taaattcttt
    27901 tttatcactt ctccacttgg caatcttaat tcaatcgttc catccatatt gaatataaca
    27961 ctatctaagc ctaatccgta actagctgta aatttttcta atttttcttg tacaggatct
    28021 actgctggag cttcctctaa tgctggatct aacatagggt cactccccac attcccttct
    28081 ggattcaaca ttccattatc cgttgagttt tctggtttta caggtttttc gtttggtgcc
    28141 tctggtaaag aatctgctgg tttattttct gttggttggt tctcaactgt tccagtagat
    28201 acttttccat tttcagatgg tttattttca ccatttcctt gaggtgcttc tcctgtaaaa
    28261 tctgccatat tctttttaat gacttctccc gatggtaaat ataattcaat tgttccgtcc
    28321 atattaaaca agacattttc tagcttcatc ccataacttt cagcaaattt tgctactttt
    28381 tcttgtacag gatccactgt aggaacttct tctaacgttg aattactagt actattccca
    28441 gtttcagaaa gtttttcttt ttctaccttc tcactagtct ttggttcttc taccttttca
    28501 tcaagttttg agttttcttg tgctttattc cttttaaatt gtggtagaat acttggttta
    28561 tcagtttgat tttctttttc caagataggt acttccacaa tataagtcga ttgattgtcc
    28621 aaataagcat ttgccatgaa ggttacagga attttatttc cggccgttct ggttgttcct
    28681 tggtttaatt tcggaatcgg taatttgatt tcaccaactt tatagttatt ttctaaataa
    28741 gcatttccat gaaattcatc aaacactctg actaaagcat cagttccttt aggcactgca
    28801 aattgagggt tcactcttaa ataagtatcc cctgcatgga aaggatagaa aatcgtttga
    28861 ctggccattt tgtaagctaa agaggttgga actgtaaatg taccatcata acttacttct
    28921 ggataatctt ttgaagcgat agtatactta aatgtttgtc ctggtaaata aggttgatct
    28981 aattcaaagt ttgcaatatt ccctactcct tctccaaata ctttaccaga tactttctcc
    29041 aatacttttc catctggtgt tattaatttt actagcatat tgatacctaa ttttttctcc
    29101 aattcaggcg gaaaactaaa agaaacgcgt ttttgaccat tggctagagt aaagttttga
    29161 ttattaaacg tactattttt taacaaatta acaacattcg ttaattcttc tccagtataa
    29221 actttattcc cttctttttt agcaactcct tcttcgggtt taaacagttc atagttactg
    29281 tgagaatgac caattccaac cggtttatgt tcatcaatcg gatctgcatg atggtgatct
    29341 ccatgcggat aaataatcgc atttttttct ttattcacga caatactttc acgtttgaca
    29401 ccatattgtt tcataatgcc agcaattttt tcttcgattt ttttatctaa atctttcatt
    29461 tctttggcat tacttggata atcctgttca tgagatgaca aagaatctaa tccattatga
    29521 ctagttttaa cttcctctaa atgtttttgc gcagccttaa tttgctcttc tgtcaagtcc
    29581 ttcttgaaga aataatgatt gtggtctccg tgactcatga caaaacctga ttcatcttca
    29641 gcgataatac gattagcatc aaatccgtat ccatcttctt catgtttctc atgtgaagtt
    29701 cctggattga ttggaagaga tggagaaggt gttgctagac tattgtttgg aagagtcggt
    29761 tgcccaattt gatttgattt tggaatgtaa tggaaatgat caccatgtct tacaatataa
    29821 gctgtagccg tttcttcaac gatatctttt ggattaaaaa tataaccatc agatgctgaa
    29881 gagagctcct tacttgtcgt taaagaagaa ggattgcttg aaagactgcc tagactagac
    29941 actacttcat taggttttgc atttgtagaa actgtagaac cagttccact gataggcacc
    30001 attctggcaa tcttttcttc taaggcagaa agcttgctgt aaggaataaa gtggtaatgg
    30061 tcgccatgcg gaatcgcaac tccatttggt gtacgactga taatcttagc agggtcaaag
    30121 accaggccat ctgattcact gtaacgttgg gcgctaggtg aatcatagag ttccttcaaa
    30181 agactctgga gattttcaga tttatttgct ggcttgctag ttgatccttt tgctacagat
    30241 tgcgtgttat tgtcactagc tgttgaagaa tagcttaact gactcggttg catatttttt
    30301 ccagccagat gtgctttagc tgctgctaat tcactagcag ataaatcgct tttgggaatg
    30361 tagtgatagt gacctccatg aggaacgata taagcattac ccgtatcttc gataatatca
    30421 gctggattaa agacataacc atcatttgtc gtatatcgtc cctgagacct tgctacagca
    30481 acattagagt taaccttctc attatctttg acatgttctt gtttttgacg attgatttca
    30541 tctttagttc gaacattatc agcatgagct gcatctttca ggtagacata atattttcca
    30601 tcgaccttga tgatataacc acccttgact tcattgacaa tatcagcgtc tttaagttga
    30661 tagtttggat ccttcatcaa gagttcttca ctaaagaggg catcataagg aactttccca
    30721 ttatagtaat gatagtggtc accgtgtgac gttacatagc cctgatctgt aattttgatt
    30781 acaatttgct cggcctgaat tccttctttc tggctaatct ggtctggtgt caagttttca
    30841 cttttctgac ttgactggct gccatctaca taagagacac gattattgtc cttattttcc
    30901 tgcgaacgat gctggtttag tgcataggca catagactca aggatacgat aacagctgat
    30961 ccagctgcta tatatttttt actgaatttc ataaatccct ca
//
LOCUS       DAVBIC010000024        30965 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.024, whole genome shotgun sequence.
ACCESSION   DAVBIC010000024 DAVBIC010000000
VERSION     DAVBIC010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30965)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30965)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30965
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.024"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            complement(<1..184)
                     /locus_tag="VQ664_001054"
     CDS             complement(<1..184)
                     /locus_tag="VQ664_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HET2789226.1"
                     /translation="MNYEASKQLTDARFKRLVGVQRTTFEEILAVLKTAYQLKHAKGG
                     RKPKLSLEDLLMATLQY"
     gene            179..433
                     /locus_tag="VQ664_001055"
     CDS             179..433
                     /locus_tag="VQ664_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HET2789227.1"
                     /translation="MHRTTIPYFVSQEVYWKVRNIGAEAIRRNCERGAIFSGKIKHHE
                     DSQFKGDHYVECYAVLDNTVIARDRITVPIDPLCGKDFIE"
     gene            777..2111
                     /gene="trmFO"
                     /locus_tag="VQ664_001056"
     CDS             777..2111
                     /gene="trmFO"
                     /locus_tag="VQ664_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HET2789228.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVANHPLIEVVRDEITELPTDVITVIATGPLTSDALAEKIHALNDGDGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRIFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEAIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
     gene            2195..2932
                     /locus_tag="VQ664_001057"
     CDS             2195..2932
                     /locus_tag="VQ664_001057"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HET2789229.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQSGNIKRVVFGENIGTTVSNNIEEKE"
     gene            2941..3498
                     /gene="frr"
                     /locus_tag="VQ664_001058"
     CDS             2941..3498
                     /gene="frr"
                     /locus_tag="VQ664_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HET2789230.1"
                     /translation="MANAIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRIHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVV
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            3558..4412
                     /gene="cvfB"
                     /locus_tag="VQ664_001059"
     CDS             3558..4412
                     /gene="cvfB"
                     /locus_tag="VQ664_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HET2789231.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTSLEVTATQDQFGWGRVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            4421..4636
                     /locus_tag="VQ664_001060"
     CDS             4421..4636
                     /locus_tag="VQ664_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HET2789232.1"
                     /translation="MRKSFYTWLMTERNPKSNNPKAILADLAFEEAAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDSIWQEYLEH"
     gene            4722..5690
                     /locus_tag="VQ664_001061"
     CDS             4722..5690
                     /locus_tag="VQ664_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HET2789233.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMALVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQEKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            5870..6370
                     /locus_tag="VQ664_001062"
     CDS             5870..6370
                     /locus_tag="VQ664_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2789234.1"
                     /translation="MIDQLSKYYSCRILTEKDIPSILSLYESNPLYFQHCPPEPNFAT
                     VKEDMLCLPEGKAKADKFFVGFWNGSDLVAVMDFVYAYPDEETVFIGLFMVDQAYQRK
                     GIGSHIVTEALAYFAKNFRKARLAYVKGNPQSQHFWEKQGFKSIGCEVKQELYTVVIA
                     EQSLED"
     gene            6373..6633
                     /locus_tag="VQ664_001063"
                     /pseudo
     CDS             6373..6633
                     /locus_tag="VQ664_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003069408.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(7000..8111)
                     /gene="ald"
                     /locus_tag="VQ664_001064"
                     /pseudo
     CDS             complement(7000..8111)
                     /gene="ald"
                     /locus_tag="VQ664_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253293.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
     gene            8288..8857
                     /locus_tag="VQ664_001065"
     CDS             8288..8857
                     /locus_tag="VQ664_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2789235.1"
                     /translation="MESIFVKFAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFYLANPLGRWGIELKDNGKFIGTIDLHKIDPVLKKAAIGYI
                     INKKYWNQGLTTEANRAVIELAFEKIGMNKLTALHDKANPASGKVMEKSGMRFSHAEP
                     YACMDQHEKGRIVTRVHYVLTKEDYFANK"
     gene            8925..9575
                     /locus_tag="VQ664_001066"
     CDS             8925..9575
                     /locus_tag="VQ664_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HET2789236.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTSVKETNLQ
                     AEVAAVSKDSSTGKEVNKEEKEEPVEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSTSKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGAKTIEKLKDYVTVD"
     gene            9559..11799
                     /locus_tag="VQ664_001067"
     CDS             9559..11799
                     /locus_tag="VQ664_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HET2789237.1"
                     /translation="MLQWIKNFSIPLIYLSFLLLWLYYAIFSVSYFALLGFVFLLVCL
                     FIQFPWKSAGKVLVICGVFGFWFLFQTWQQSQVSQNLVDSVERVRILPDTIKVNGDSL
                     SFRGKSDGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFDYQGY
                     LKTQGIYQTLNIKRIQSLQKVGSWDIGENLSSLRRKAVVWIKMHFPDPMRNYMTGLLL
                     GHLDTDFEEMNELYSSLGIIHLFALSGMQVGFFMDGFKKLLLRLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGEGLKAVTSESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDL
                     VFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVASRPLVFGQPNEWLLILLLI
                     SLALVYDLRKNIKKLTVLCLLITGLFLLTKHPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESYKKIKKWQEKMTTSNAQRSLIPYLKSRGVAKIDQLILTNTDKEHVGDL
                     SEMTKAFHVGEILVSKDSLKQKEFVAELQATQTKVRSMIVGENLPIFGSQLEVLSPRK
                     MGDGGHDDTLVLYGKFLDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSS
                     SPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGLDSW
                     KIESVR"
     gene            11979..12167
                     /locus_tag="VQ664_001068"
     CDS             11979..12167
                     /locus_tag="VQ664_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789238.1"
                     /translation="MTVTKSYKYDWNTVLEYSTNYHDHQYAWIPEWSRYYSYSEYKVG
                     GGWNYARYEVINYYTGGY"
     gene            12199..12786
                     /locus_tag="VQ664_001069"
     CDS             12199..12786
                     /locus_tag="VQ664_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2789239.1"
                     /translation="MLNLTHVTLKTRQVILQDADFTFKKGRIYGLLAINGSGKTTLFR
                     AMSKLLPLSSGHIAVPPSLFYYESVEWLDGNLSGMDYLRLIKNIWKSDLNLRDEIAYW
                     EMADYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDICDRVVTIHQGQIEEV"
     gene            12790..13965
                     /locus_tag="VQ664_001070"
     CDS             12790..13965
                     /locus_tag="VQ664_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789240.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIILALFVSVLGVTFYLNSQTANSHS
                     LESRLESRIAANERAINENEEKLSQMSDTSSEEYQFAKNNLDVQKNLLTRKTEILTLL
                     KEGRWKEAYYLQWKDEEKNYEFVSNDPTASSGLKMGVDRERKIYQALYPLNIKAHTLE
                     FPTHGIDQIVWILEVIIPSLFVVAIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISS
                     LGVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYPIYSLVNQEVTIGKIQDVLFPG
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQRIAHLIPF
                     TYLRSVEILSGRLPKQIDNVDLNWSMGMVLLPCLIIFLLLGILFIERWGSSQKKRIF"
     misc_feature    14139..14270
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            14286..14816
                     /gene="infC"
                     /locus_tag="VQ664_001071"
     CDS             14286..14816
                     /gene="infC"
                     /locus_tag="VQ664_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HET2789241.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     gene            14849..15049
                     /gene="rpmI"
                     /locus_tag="VQ664_001072"
     CDS             14849..15049
                     /gene="rpmI"
                     /locus_tag="VQ664_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HET2789242.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            15101..15460
                     /gene="rplT"
                     /locus_tag="VQ664_001073"
     CDS             15101..15460
                     /gene="rplT"
                     /locus_tag="VQ664_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HET2789243.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            15518..15898
                     /locus_tag="VQ664_001074"
     CDS             15518..15898
                     /locus_tag="VQ664_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET2789244.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            16148..16948
                     /locus_tag="VQ664_001075"
     CDS             16148..16948
                     /locus_tag="VQ664_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HET2789245.1"
                     /translation="MNPTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVNQRVCEDGPVFRTGTVVL"
     gene            16911..17897
                     /locus_tag="VQ664_001076"
     CDS             16911..17897
                     /locus_tag="VQ664_001076"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HET2789246.1"
                     /translation="MVLFSAQEQLYYKEKIMTTNRLQVSLPGLDLKNPIIPASGCFGF
                     GQEYAKYYDLNLLGSIMIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAE
                     KLPWLEREYPNLPIIANVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGL
                     LIGQDPDLAYDVVKAAVEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVG
                     MRFDLKTRKPILANGTGGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEM
                     YLAGASAIGVGTANFTNPYACPDIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            17939..19840
                     /locus_tag="VQ664_001077"
     CDS             17939..19840
                     /locus_tag="VQ664_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HET2789247.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIKADANYAENEWLKQGDDYFYLKSGGY
                     MAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKA
                     DGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFY
                     IKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGKIAEKEWVYDS
                     HSQAWYYFKSGGYMTANEWIWDKESWFYLKSDGKMAEKEWVYDSHSQAWYYFKSGGYM
                     AKNETVDGYQLGSDGKWLGGKATNENAAYYQVVPVTANVYDSDGEKLSYISQGSVVWL
                     DKDRKSDDKRLAITISGLSGYMKTEDLQALDASKDFIPYYESDGHRFYHYVAQNASIP
                     VASHLSDMEVGKKYYSADGLHFDGFKLENPFLFKDLTEATNYSAEELDKVFSLLNINN
                     SLLENKGATFKEAEEHYHINALYLLAHSALESNWGRSKIAKDKNNFFGITAYDTTPYL
                     SAKTFDDVDKGILGATKWIKENYIDRGRTFLGNKASGMNVEYASDPYWGEKIASVMMK
                     INEKLGGKD"
     gene            complement(19901..21556)
                     /gene="pavA"
                     /locus_tag="VQ664_001078"
     CDS             complement(19901..21556)
                     /gene="pavA"
                     /locus_tag="VQ664_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HET2789248.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEI
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTKSLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQVGEPLANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            21661..22158
                     /gene="ybeY"
                     /locus_tag="VQ664_001079"
     CDS             21661..22158
                     /gene="ybeY"
                     /locus_tag="VQ664_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HET2789249.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAQKLGKEDKEMAVTFVT
                     NERSHELNLGYRDTDRPTDVISLEYKPELEIAFDEEDLLENPELAEMMSEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            22139..22534
                     /locus_tag="VQ664_001080"
     CDS             22139..22534
                     /locus_tag="VQ664_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HET2789250.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFAITGIFTAIKEERNMRKHAVTAL
                     VVILAGFGFQVSRIEWLFLLLSIFLVVAFEIINSAIENVVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            22551..23450
                     /gene="era"
                     /locus_tag="VQ664_001081"
     CDS             22551..23450
                     /gene="era"
                     /locus_tag="VQ664_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HET2789251.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPDRFLVSEMVREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEREY"
     gene            23499..24323
                     /gene="mutM"
                     /locus_tag="VQ664_001082"
     CDS             23499..24323
                     /gene="mutM"
                     /locus_tag="VQ664_001082"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HET2789252.1"
                     /translation="MPELPEVETVCRCLEKLIIGKKISSIEIRYPKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFYLTDKVLISHLRMEGKYFYYPDQGPERKHAHVFFHFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQSALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARSSQTLTAEEATAIHDQTIAVLSQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQGCVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            24323..24928
                     /locus_tag="VQ664_001083"
     CDS             24323..24928
                     /locus_tag="VQ664_001083"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HET2789253.1"
                     /translation="MGKIIGITGGIASGKSTVTNFLRQQGFQVVDADAVVHQLQKPGG
                     RLFEALVQHFWQEIILENGELNRPLLASLIFSNPDEREWSKQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            24915..26114
                     /locus_tag="VQ664_001084"
     CDS             24915..26114
                     /locus_tag="VQ664_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HET2789254.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSEQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            26114..26263
                     /gene="rpmG"
                     /locus_tag="VQ664_001085"
     CDS             26114..26263
                     /gene="rpmG"
                     /locus_tag="VQ664_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HET2789255.1"
                     /translation="MRVKINLKCSSCGSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            26303..26536
                     /gene="secG"
                     /locus_tag="VQ664_001086"
     CDS             26303..26536
                     /gene="secG"
                     /locus_tag="VQ664_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HET2789256.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            26638..28992
                     /gene="rnr"
                     /locus_tag="VQ664_001087"
     CDS             26638..28992
                     /gene="rnr"
                     /locus_tag="VQ664_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HET2789257.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLTLEIKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     DGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKEYHK
                     IVSSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMRAVEGEPYADVLSMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRRYPD
                     LLVHRMIRDYGRSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSHSGRGRGSNRRSDKKEDKRKS
                     GRSNDKRKHSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            28955..29422
                     /gene="smpB"
                     /locus_tag="VQ664_001088"
     CDS             28955..29422
                     /gene="smpB"
                     /locus_tag="VQ664_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HET2789258.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKKQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            29438..30298
                     /gene="tehB"
                     /locus_tag="VQ664_001089"
     CDS             29438..30298
                     /gene="tehB"
                     /locus_tag="VQ664_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HET2789259.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEDVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEAMQTVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIEQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            30371..>30965
                     /gene="coiA"
                     /locus_tag="VQ664_001090"
     CDS             30371..>30965
                     /gene="coiA"
                     /locus_tag="VQ664_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HET2789260.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQG"
BASE COUNT         9194 a         5729 c         7092 g         8950 t
ORIGIN      
        1 catattgaag agtggccata agaaggtctt ctaggcttaa tttaggtttt cgtccacctt
       61 ttgcgtgttt aagttgataa gctgttttta atacagctaa tatctcttca aaagtcgtgc
      121 gctgaacacc aacaagacgc ttaaatcgtg catcagttag ttgtttactt gcttcataat
      181 tcatagaact actataccat attttgtttc gcaggaagtc tattggaaag taagaaatat
      241 tggagctgag gcgattagaa gaaattgtga gcgtggtgct attttttcag gtaaaataaa
      301 acatcacgaa gattctcagt ttaaaggaga ccactatgtt gaatgttatg ctgttttaga
      361 taatacggtt atagcaagag atagaataac agtccctatc gatccgttat gtggaaaaga
      421 ttttatagag tagcatataa ttgattctta actggaatac tctctatctc tttacatcaa
      481 gaaaatgact aaacagggaa gtttgccttc ttcccttttt ttgttatact agtagaagaa
      541 aaaaatagaa agatttgtgg gagtgaaaaa gtccggggga ctttttcagc ttgagccaag
      601 aaattcgaga gcgaggaaag tccgggggac tttttcagcc tgagccaaga aattcgagag
      661 cgaagtaagt ccaatggact ttttcagcct gagccaagaa actcgaaagc tcgtaagtct
      721 gattggcttt ttcaatgtga atcttaactt cacactccca aagaggtatt agtgtcgtgt
      781 ctcaatctta tatcaatgtt atcggtgctg gtttggcagg ttctgaagca gcttaccaaa
      841 tcgcagagcg tggtattcca gttaaactat atgaaatgcg tggtgtcaag tcgactcccc
      901 agcataaaac agacaatttt gctgagttgg tttgttccaa ttctttgcgt ggggatgctt
      961 tgacaaatgc agttggtctt ctcaaggaag aaatgcgtcg cttgggttct gttatcttgg
     1021 aatctgctga ggctacacgt gttcctgcag gtggtgccct tgcagtggac cgtgatggtt
     1081 tctctcaaat ggtgaccgaa aaagttgcca accacccctt gattgaagtg gttcgtgatg
     1141 aaattacaga attgccgaca gatgttatta cggttatcgc tactggtcct ttgacaagtg
     1201 atgccttggc tgaaaagatt catgccctta atgacggtga tggtttttat ttctacgatg
     1261 cggcagcgcc tattatcgat gtcaacacta tcgatatgag caaggtctac ctcaaatcac
     1321 gttatgataa gggagaagcg gcctacctca atgcccctat gaccaagcaa gaatttatgg
     1381 atttccatga agctttggtc aatgcagaag aagcaccgct taattctttt gaaaaagaaa
     1441 agtactttga aggctgtatg cctatcgaag tcatggccaa acgtggcatt aaaactatgc
     1501 tttatggccc tatgaagcca gtcggtcttg agtacccaga cgactataca ggacctcgtg
     1561 atggagaatt taaaacacct tatgcggttg tgcaacttcg tcaggacaat gcagctggta
     1621 gcctctacaa tattgttggt ttccagaccc acctcaaatg gggagaacaa aagcgtatct
     1681 tccaaatgat tccgggtctt gaaaatgcag agtttgtccg ttatggtgtc atgcatcgca
     1741 attcttacat ggattcacca aatcttcttg agcagactta ccgttctaag aaacaaccaa
     1801 atctcttctt tgctggtcag atgacggggg tggaaggcta tgttgagtcg gcggcttcag
     1861 gcttagttgc gggaattaac gcagctcgtc tcttcaagga agaaagcgag gctattttcc
     1921 ccgagacgac agcgattgga agcttagctc attacattac ccatgccgac agcaaacatt
     1981 tccaaccaat gaatgtcaat tttgggatca tcaaggagtt ggaaggcgag cgtatccgtg
     2041 ataagaaggc tcgttatgaa aaaattgcag agcgtgccct tgccgactta gaggaatttt
     2101 tgactgtcta atttttttga aagaattgct catgatacta taaaaatctt agaaattgtg
     2161 ataaaatagg taggatgaaa gaaggagagt gaaaatggcg aatcccaagt ataaacgtat
     2221 tttaatcaag ttatcaggtg aagcccttgc cggtgaacgt ggcgtaggga ttgatatcca
     2281 aacagttcaa acaatcgcaa aagagattca agaagttcat agcttaggta tcgaaattgc
     2341 ccttgttatt ggtggaggaa atctctggcg tggagaacct gcagcagaag caggtatgga
     2401 ccgtgttcag gcagattaca ctggaatgct tgggactgtt atgaatgctc ttgtgatggc
     2461 agattcattg caacaagttg gggttgatac gcgtgtacaa acagctattg ctatgcaaca
     2521 agtggcagag ccttatgtcc gtggacgtgc ccttcgtcac cttgaaaaag gccgtatcgt
     2581 tatctttggt gctggaattg gttcaccata cttctcgaca gatacaacag cggcccttcg
     2641 tgcagctgaa atcgaagcgg atgccatcct catggctaaa aatggtgtcg atggtgttta
     2701 caatgccgat cctaagaaag ataagacagc tgttaagttt gaagaattga cccaccgtga
     2761 cgttatcaat aaaggtcttc gtatcatgga ctcaacagct tcaaccctct caatggacaa
     2821 cgacattgac ttggttgtct tcaacatgaa ccaatcaggc aacatcaaac gtgtcgtatt
     2881 tggtgaaaat atcggaacaa cagtttcaaa taatatcgaa gaaaaggaat aagaaagaat
     2941 atggctaacg caattattga aaaagctaaa gagagaatga cccagtctca ccaatcactt
     3001 gctcgtgaat ttggtggtat ccgtgctggt cgtgccaatg caagcttgct tgaccgtata
     3061 catgtagaat actatggagt tgaaactcct cttaaccaaa tcgcttcaat tacgattcca
     3121 gaagcgcgtg ttttgttggt aacaccattt gacaagtctt cattgaaaga catcgaacgt
     3181 gccttgaacg cttctgatct tggtatcaca ccagctaatg acggttctgt gattcgcttg
     3241 gttgtcccag ctcttacaga agagactcgt cgtgaccttg ctaaagaagt gaagaaggtc
     3301 ggcgaaaatg ctaaagtggc tgtccgcaat atccgtcgcg atgctatgga cgaagctaag
     3361 aaacaagaaa aagcaaaaga aatcactgaa gacgaattga agactcttga aaaagacatt
     3421 caaaaagtaa cagacgatgc tgttaaacac atcgacgata tgactgccaa caaagagaaa
     3481 gaacttttgg aagtctaaaa ataaacagaa aaactcagtt ggcattgctg gctgagtttt
     3541 attcgaaaga aggaaatatg aatacaaatc ttgcaagttt tatcgttgga ctgatcatcg
     3601 atgaaaacga ccgtttttac tttgtgcaaa aggatggtca aacctatgct cttgctaagg
     3661 aagaaggcca acatacagta ggggatacgg tcaaaggttt tgcatacacg gatatgaagc
     3721 aaaaactccg cctgacaagc ttagaagtga ctgccactca ggaccaattt ggttggggac
     3781 gtgtcacaga ggttcgtaag gacttgggtg tctttgtgga tacaggcctt cctgacaagg
     3841 aaatcgttgt gtcactcgat attctccctg agctcaagga actctggcct aagaagggcg
     3901 accaactcta catccgtctt gaagtggata agaaagaccg tatctggggt ctcttggctt
     3961 atcaagaaga cttccaacgt cttgctcgtc ctgcctacaa caacatgcag aaccaaaact
     4021 ggccagccat tgtttaccgt ctcaagctat caggaacttt tgtttaccta ccagaaaata
     4081 atatgcttgg ttttattcat cctagcgagc gttacgcaga gccacgtttg gggcaagtat
     4141 tagatgcgcg cgttattggt ttccgtgaag tggaccgcac tttgaacctc tccctcaaac
     4201 cacgctcctt tgaaatgttg gaaaacgatg ctcagatgat tttgacttat ttggaaagca
     4261 atggcggttt catgacctta aatgacaagt catctccaga cgacatcaag gcaacctttg
     4321 gcatttctaa aggtcagttc aagaaagctt taggtggtct tatgaaggct ggtaaaatca
     4381 agcaggacca gtttggtaca gagttgattt agggaggctt atgagaaaat cattttacac
     4441 ttggctcatg accgagcgca atcctaaaag taacaatccc aaagcaattt tggcagacct
     4501 cgcttttgaa gaggcagctt ttccaaaaca tacagatgat tttgatgagg tcagtcgctt
     4561 tttggaggag catgccagtt tctcttttaa cctaggagat tttgacagca tttggcagga
     4621 atatctagaa cactagcatt tattcattgg gtttgggcta gtaatttctc catccctctg
     4681 ctataataaa aagaaataaa aggattagag aggttcttta tttgaaggaa cattcaatag
     4741 acattcaact gagtcatcca gatgacctgt ttcatctttt tggttccaat gaacgccatc
     4801 ttcgtttgat ggaagaagag cttgatgttg tgattcatgc tcgtacggag attgtccagg
     4861 ttttgggaga agagtctgct tgcgaggaag cccgtcaggt tattcaagct ctcatggcct
     4921 tggtaaatcg tgggatgacc gttggtacgc cagatgtagt gacggctatt agtatggtca
     4981 aaaatgatga aattgacaag tttgtcgccc tttacgaaga agaaatcatc aaggataata
     5041 ctgggaagcc tatccgcgtc aaaaccttag gtcaaaaact ttatgtggac agtgtcaaac
     5101 agcatgatgt gacctttgga attgggccag caggtacagg gaagaccttc cttgcagtga
     5161 ccttggcagt gactgccctt aaacgtgggc aagtcaagcg aattatccta actcgtccag
     5221 cggtggaagc gggagagagt cttggatttc ttccgggtga tcttaaggag aaggtggatc
     5281 cttaccttcg tcctgtttac gatgccttgt atcaaattct tgggaaagac caaacgactc
     5341 gtctcatgga gcgtgaaatt atcgaaattg cgccccttgc ctatatgcgt ggccggacct
     5401 tggatgatgc ctttgtcatt ctcgatgagg cgcaaaacac gaccatcatg cagatgaaga
     5461 tgttcttgac gcgtttaggc tttcattcta agatgattgt caatggagat atcagtcaga
     5521 ttgacctgcc acgtaatgtc aagtccggtt tgattgatgc tcaagagaaa ctcaagaaca
     5581 tccatcagat tgactttgtt catttttcag ccaaggatgt ggttcgccat ccagttgtcg
     5641 ctcagattat ccgagcctat gaatattcta ctgaagttgc acacgactga ttttgaggaa
     5701 gttcgcctgc aaaagaatat acttttgaga gaggaaaatc cagttgtata ggctaaaggt
     5761 ttgagacaac gattaggcac gatggaaaga acttttatgt ggctgatgac gatcagtgca
     5821 tcttcctgtg tcataatcac agggcacaag aaagtaggaa tttgaaaaga tgattgacca
     5881 actatctaag tattacagtt gtaggatact aactgaaaag gatattccaa gtattttatc
     5941 tttatatgaa agtaatcctc tgtattttca gcattgtcca ccagagccaa attttgcaac
     6001 tgtaaaagag gacatgcttt gtctacctga aggtaaagct aaggctgata agttttttgt
     6061 tggattttgg aatggctctg accttgtggc tgttatggat tttgtctatg catatcctga
     6121 tgaggagact gtttttattg gtttgtttat ggttgatcaa gcctatcaga ggaaagggat
     6181 tggtagtcat attgtgacag aagcactagc ttattttgct aagaactttc gaaaggcacg
     6241 tttggcttat gttaagggaa atccgcaatc tcagcatttt tgggaaaagc agggctttaa
     6301 atcaattgga tgcgaggtta agcaagaact ctatacggtt gttatcgctg aacagagcct
     6361 agaagattag aaatggcatc aagtaagaac tatttggaat ttgttttgga acaattatca
     6421 ggattagatg atgtgactta ccgttccatg attggggagt atattcttta cttccgcggc
     6481 aagattattg gcggcattta tgacgatcgc tttttagtta aacccgtgca agcagtctta
     6541 gataagattg accaatcttc ttttgagttt ccatacaaag gtgccaaaga aatgatttga
     6601 gtggaagaac ttgataataa gatgtttcta taagacctga ttttagctat gtataaccaa
     6661 ctgccaacgc ccaaacctaa aaagaaaaag caagggtgaa cgaagtaaaa aagaagtctg
     6721 ctaaggccct gtctttgcac gggtaaaatt ttatatataa aaagaagctg ggactaaaga
     6781 gctcagcttc ctttggttta tataattgtc attacaagac gaagtggttg ggcgaaactc
     6841 tgttgacttt attcaattta gagtttctta tgcacaattg agtctggaac gaaagtcttc
     6901 agttgcaaag tatacagtac aataaaccaa cgatgtaata gctgatgaca caaagcacag
     6961 tgggtaggac ttgcgaagtc acccttttct tttcaaaatt tatactaaat cattgatatc
     7021 agtgtagtca cgattaagtc cttgagcaac tggtaggcta gtcaagtaac cttgataagt
     7081 ggtcacacct tgacgcaagc cttcatcttc agagattgct tgtgcgaatc ctttgccagc
     7141 caaagcttcg atataaggaa gagtgacatt ggttagggcg atggttgaag tgcgggcaac
     7201 cgcaccaggg atattggcaa cggcatagtg gagaacaccg tgtttttcat agacgggttc
     7261 atcgtgcgtt gtcacacggt cagctgtttc gataacgcca ccttggtcaa cagcaacgtc
     7321 aacgatacag agcctggacg catttgtttg accatctcat ctgtcaccaa ttccggtgct
     7381 tttgcaccag ggatgagaat ggctccaatc accacatcag catctctcac acttgcttca
     7441 atgttgaatg aattagatat aatagtttga atttgacttc caaagacttc ttctagaact
     7501 gagagacgct tggcactaat atctaaaata gtcacttgag caccaagacc aagggcgatg
     7561 cgggcagcat gtgtaccgac gacaccatca ccgatgatag ttacttttcc ttttggaaca
     7621 cctggtacac caccaagtag aacaccagag ccaccagctt gcttagtaag gaagtgagct
     7681 ccgatttgaa cagccatacg acctgcaacc tcactcatag gaacgaggag cggtagttgt
     7741 ccttgattgt cacgaacagt ttcataggca attcctgttg tttttgctgc taacatagca
     7801 tctgctaatt ctggagcagc ggccatgtgc aagtaggtga agagaagaag atcgtcgcgc
     7861 aagtaaccgt attcagaact taaaggttct tttactttca caaccaactc tgctgcccaa
     7921 gcttcaccag cagtagcgac aatctcagct ccttgctttt gatagtcagc atcagtaaag
     7981 ccagaaccga gaccagcatt tgtttcgata aggacacgat gaccacgact aactaagcta
     8041 tgaacacctg caggtgtgag ggcgacacgg ttttcgttat ttttaatttc ttttgggatt
     8101 ccgattaaca ttgagataac ctacctttca attgacggtc ttgttttggt tgtcacattc
     8161 cagttcataa atcaaaaatg tgacggtttc attgtatatg aaaccgcttc aaaaatcaag
     8221 aaaaacttgt catccaaatt tttttatgct agactagtga aaatcaagct ctaatggagg
     8281 gaaaagtatg gaatcaatat ttgtgaaatt tgcccagtat ccgtctatag aaacggagcg
     8341 tttattgctt agacctgtaa ctttggatga tgcggaagca atgtttgact atgcctcgga
     8401 caagggtaat acacgttaca cttttccaac caatcaaagc ttggaagaaa ccaagaataa
     8461 cattgctcag ttctacttgg ctaatccctt gggacgttgg gggattgaat taaaagataa
     8521 cggcaagttt atcggaacta ttgacttaca caagattgat cctgttctta agaaggcagc
     8581 tattggctac attatcaata aaaagtattg gaatcaagga ttaacgacag aagccaatcg
     8641 tgctgtgatt gagctagctt ttgagaagat agggatgaat aagttgactg cccttcacga
     8701 taaggctaat cccgcgtcag gaaaggtcat ggagaaatca ggcatgcgtt tttcccatgc
     8761 agaaccatat gcttgtatgg accagcatga aaaaggccga atcgtgacaa gagttcatta
     8821 tgtcttgacc aaggaagact attttgcaaa taaataagca gttgaaaaga aatttttcga
     8881 ctgttttttc ttcctcttac gaataatcta agagaggaga aaatatggaa gcaattatcg
     8941 agaaaatcaa agagtataaa atcatcgtca tctgtactgg tctgggcttg cttgtaggag
     9001 gatttttcct gctaaagcca gctccacaaa catctgtcaa agagacgaat ttgcaggctg
     9061 aagttgcagc tgtttccaag gactcatcga ccggaaagga agtgaacaag gaagagaagg
     9121 aagaaccagt tgaacaagat ctaatcacag tagatgtcaa aggtgctgtc aaatcgccag
     9181 ggatttatga cttgcctgta ggtagtcgag tcaatgatgc tgttcagaag gctggtggct
     9241 tgacagagca agcagacagc aagtcgctca atctagctca gaaagttagt gatgaggctc
     9301 tggtttacgt tcctactaag ggagaagaag cagttagtca acagactggt tcggggacag
     9361 cttcttcaac aagcaaggaa aagaaggtca atctcaacaa ggccagtctg gaagaactca
     9421 agcaggtcaa gggactggga ggaaaacgag ctcaggacat tattgaccat cgtgaggcaa
     9481 atggcaagtt caagtcagta gacgagctca agaaggtctc tggcattggt gccaagacca
     9541 tagaaaaact taaagactat gttacagtgg attaagaatt tctctattcc cctaatttac
     9601 ctgagttttc tattactatg gctttactac gccattttct cagtatccta ttttgctttg
     9661 ttgggttttg tttttctgct agtctgcctc tttatccaat ttccttggaa atcagcaggt
     9721 aaagttctag tgatttgtgg agtctttggc ttctggtttc tgtttcaaac ttggcaacag
     9781 agtcaagtga gtcaaaattt ggtggattct gttgaaaggg tacggatttt accagacact
     9841 attaaggtta acggtgacag tctgtccttt cgtggtaagt ctgatggtcg tgctttccaa
     9901 gtctattata aactccagtc cgaggaggag aaagaagcct ttcaagcttt aactgacctt
     9961 catgagatag gactagaagg gaagctttcg gagccagaag ggcagagaaa ttttggtggc
    10021 tttgactacc aaggctatct gaagactcag ggaatttacc agacactcaa tattaaaaga
    10081 atccagtcac tccaaaaggt tggcagttgg gatataggtg aaaacctgtc cagtttacgt
    10141 cgaaaggctg tggtttggat taagatgcac ttcccagacc ctatgcgcaa ttacatgaca
    10201 ggactcttgc taggacatct ggacaccgat tttgaggaga tgaatgagct ttattccagt
    10261 ttaggaatta ttcacctttt tgccttgtca ggtatgcagg tagggttttt catggacgga
    10321 tttaagaaac tacttttacg attgggcttg acacaagaaa agttgaagtg gctgacttat
    10381 cccttttccc ttatctatgc gggactaact ggattttcag catcggttat tcgcagtctc
    10441 ttgcaaaagc tactggctca acatggggtt aagggcttgg ataattttgc cttgacggtg
    10501 cttgtcctct ttattgtcat gccaaacttt ttcttgacag caggaggagt cttgtcctgt
    10561 gcttatgctt ttatcctgac catgaccagc aaagaagggg aggggctcaa ggctgttact
    10621 agtgaaagtc tagtcatctc cttgggcata ttgcccattc tatccttcta ttttgcggaa
    10681 tttcaacctt ggtctatcct tttgaccttt gtcttttcct ttctttttga cttggtcttc
    10741 ttaccgctct tgtctatctt atttgtcctt tcctttctct atccagtcat tcagctgaac
    10801 tttatctttg aatggttaga gggcattatt cgcttggtct cgcaggtggc aagtagaccg
    10861 cttgtctttg gacaacccaa tgaatggctt ttaatcctat tgttaatttc tttggctttg
    10921 gtctatgatt tgaggaaaaa cattaaaaag ctaacggtat tgtgcttatt gattacaggg
    10981 ctctttctcc tgaccaagca tccactggaa aatgaaatca ccatgctgga tgtggggcaa
    11041 ggagaaagta ttttcctacg ggatgtaact gggaaaacca ttctcataga tgtaggtggt
    11101 aaggcagaat cttataagaa aatcaaaaaa tggcaagaaa agatgacgac cagcaatgcc
    11161 cagcgaagct tgatacccta tctcaaaagt cgaggagtag ctaagattga ccagctaatt
    11221 ttgactaaca cggacaagga gcatgttgga gatttgtcag agatgaccaa ggctttccat
    11281 gtaggggaga ttctagtatc aaaagacagt ctgaaacaga aggaatttgt ggcagaacta
    11341 caggcgactc aaacaaaggt gcgtagtatg atagtagggg agaacttacc catttttgga
    11401 agtcagttag aagttctatc tccaaggaaa atgggagatg gaggacacga tgatacccta
    11461 gttctgtatg ggaaattctt ggataagcaa tttctcttca cgggaaattt ggaggagaaa
    11521 ggagagaagg acttgctgaa gcactatcca gacttgaaag taaatgtttt gaaagctagc
    11581 caacatggca ataaaaaatc atcaagtcca gcctttctag aaaaactcaa accagagctt
    11641 actcttatct cagttggaaa gagcaatcga atgaaactcc cccatcagga aacattgaca
    11701 cgactggaag gtatcaatag caaagtttat cgaactgacc agcaaggagc tatacgtttt
    11761 aaggggttgg atagttggaa aatcgaaagt gttcgatagg aaggataaat gttgtagatt
    11821 agtgaaataa actaaaaatt tgttgcataa taatgataaa aacggcataa tgaaaacgta
    11881 ttcaatattg aggatataaa atcattaaaa atcagcaaaa gttgttttag ttagttagtt
    11941 tataatctat tggtcttctt cagtccagtg tatctgctgt gacagtcact aaaagttaca
    12001 agtatgattg gaatacggtt ttggaatata gtaccaacta tcacgaccat cagtatgctt
    12061 ggattccgga atggtctcgt tattacagct attctgagta taaagttggc ggaggctgga
    12121 actacgctcg ttatgaggtc ataaactact atactggagg ttattaatcc ttaaagagtg
    12181 agaaaaggag ggctggatat gttaaatctt actcatgtta ccttaaaaac gcgacaagtc
    12241 atcttgcaag atgcggattt tacctttaaa aagggtagga tttatggcct tcttgctatc
    12301 aatggctcgg gaaagacgac actattccga gctatgagca agttgcttcc ccttagtagt
    12361 ggacacatcg cagttcctcc ttctttgttt tattatgaga gcgttgaatg gctggatgga
    12421 aacttaagtg ggatggacta ccttcgtctc ataaaaaaca tctggaagtc agacctaaac
    12481 ttgagagatg aaatcgccta ctgggaaatg gctgactata tcagtcttcc catccgcaag
    12541 tattccttag ggatgaagca acgcttggtg attgctatgt attttctcag tcaggccaaa
    12601 tgctggctca tggatgagat tacaaatggc ttagacgagt attatcgaca gaagtttttt
    12661 gataggctag cacaaatcga tagacaagaa cagctggttc ttttaagttc ccactataag
    12721 gaagagttgg ttgatatctg cgatagagta gtaaccattc atcaggggca gatagaagag
    12781 gtttagttta tgaaagatgt tagtctattt ttattgaaaa aagttttcaa aagtcgttta
    12841 aactggatta tcttagcttt atttgtatct gtactcggtg ttacctttta tttaaatagt
    12901 cagactgcaa actcacacag cttggagagc aggttggaaa gtcgcattgc agccaacgag
    12961 agggctatca atgaaaatga agagaaactc tcccaaatgt ctgataccag ctcggaggaa
    13021 taccagtttg ctaaaaataa tttagacgtg caaaaaaatc ttttgacgcg aaagacagaa
    13081 attctaactt tactaaaaga agggcgctgg aaagaagcct actatctgca gtggaaagat
    13141 gaagagaaga attatgaatt tgtatcaaat gacccgactg ctagctctgg cttaaaaatg
    13201 ggggttgacc gcgaacggaa gatttaccaa gccctgtatc ccttgaacat aaaagcacat
    13261 actttggagt ttccgaccca cgggattgat cagattgtct ggattttaga ggttatcatc
    13321 ccaagcttgt ttgtggttgc gattattttt atgctaacac aactatttgc agaaagatat
    13381 caaaatcatc tggacacagc tcacttatat cctgtttcaa aagtgacatt tgcaatatcc
    13441 tctcttggag ttggagtggg atatgtaact gtgctgttta tcggaatctg tggcttttct
    13501 tttctagtgg gaagtctgat aagtggtttt ggacagttag attatcccta cccaatttat
    13561 agcttagtga atcaagaagt aactattggg aaaatacaag atgtattatt tcctggcttg
    13621 ctcttagctt tcttagcctt tatcgtcatt gtggaagttg tgtacttgat tgcttacttt
    13681 ttcaagcaaa aaatgcctgt cctctttctt tcactcattg ggattgttgg cttattgttt
    13741 ggcatccaaa caattcagcc tcttcaaagg attgcacatc tgattccctt tacttacttg
    13801 cgttcagtgg agattttatc tggaagatta cctaagcaga ttgataatgt cgatctaaat
    13861 tggagcatgg gaatggtctt acttccttgc ctgattatct ttttgctatt gggaattcta
    13921 tttattgaaa gatggggaag ttcacagaaa aaaagaattt tttaatagat tctagctttc
    13981 ctataggtag ggaaaataag taaaaactaa catagagagg gaatcaactt gattctctct
    14041 ttttgattcg aaaaccaaac caaaatacaa acacaaactt ttcaaaaaat aactttttat
    14101 cttgacaaga gctagaaaac ttggtatcat ataaaagttg agaaaagcag aagtgagagc
    14161 ttctcgcctt gtgacattaa gttgcctggc cctacggatg aaaagtttcg aagaaacgct
    14221 atcataacgt gcgggcttgt atatttacga gtccgctatt gtttttctct aataaaacaa
    14281 aagaggtgaa aaccatagca aagcaagact tattcatcaa tgatgagatt cgtgtacgtg
    14341 aagttcgctt gattggtctt gaaggagaac agctaggcat caagccactc agtgaagcgc
    14401 aagctttggc tgataacgct aatgttgacc tagtattgat tcaaccccaa gccaaaccgc
    14461 ctgttgcaaa aattatggac tacggtaagt tcaaatttga gtaccagaag aagcaaaaag
    14521 aacaacgtaa aaaacaaagc gttgttactg tgaaagaagt tcgtctaagt ccaactattg
    14581 acaagggtga ctttgataca aaacttcgta atgcacgtaa gttccttgaa aaaggaaata
    14641 aagttaaggt atctattcgc tttaagggtc gtatgattac ccataaagag attggtgcaa
    14701 aagttttagc cgagtttgct gaagcaactc aagatattgc catcatcgaa caacgtgcta
    14761 aaatggatgg acgtcaaatg ttcatgcaat tggcgccagc gactgacaaa aaataattgt
    14821 cagaaagtta aataaaggag aaaaaattat gccaaaacaa aaaacacacc gcgcatcagc
    14881 taaacgtttc aaacgtacag gttctggtgg acttaaacgt ttccgtgctt acacttctca
    14941 ccgtttccac ggaaaaacta agaaacaacg tcgtcatctt cgtaaagcat ctatggtgca
    15001 ttcaggagat tacaaacgta tcaaagcaat gcttactcgc ttgaaataat agcttgactg
    15061 taagtaaaca attctaggaa atatttggag gaaataaaac atggcacgtg ttaaaggtgg
    15121 cgttgtatca cgcaaacgtc gtaaacgtat tcttaaatta gcaaaaggtt actatggagc
    15181 taaacacatc ttgttccgta ctgcaaaaga acaagtaatg aactcttact actatgcata
    15241 ccgtgaccgt cgtcagaaaa aacgtgactt ccgcaaattg tggatcactc gtatcaatgc
    15301 ggcagctcgt atgaacggac tttcatactc acaattgatg catggtttga aattggctga
    15361 gatcgaagtt aaccgtaaaa tgcttgctga cttggctgtt aacgatgcag tagctttcac
    15421 agctcttgca gatgcagcta aagcaaaact tggtaaataa caactgatga gactggaaca
    15481 ggattgtcca gtctttttaa aaataaagga gaaaaatatg gcttcaaaaa tgctacacac
    15541 ttgcttacga gtagaaaatc ttgaaaaatc aatcgcattt tatcaagatg cttttggttt
    15601 taaagaattg cgtcgcagag attttccaga ccatgccttc acgattgtct atctaggtct
    15661 tgagggtgat gactatgagt tggagttgac ttataactac gatcacggtc cgtatgtggt
    15721 tggtgatggg tttgcccata tcgccctcag tacacctgat cttgaggcac ttcatcaaga
    15781 acacagtgca aaaggctatg aagtgactga gccaaatggt ctaccaggaa ctacaccaaa
    15841 ctattacttt gtcaaagacc ctgatggata taaggtcgaa gtcattcgtg aaaaataatt
    15901 tcgtgcaagt taagtagaat attcgttttt tacttgactt tttttagctg aaagagtata
    15961 ctaataaaaa ttcaaccttt aaggggagtc cagagagact cacaaggtgt cagataaaag
    16021 aatagtgcaa ttttctagag gagacttttt gagtgtgctc tcttgtgttg tacgatttta
    16081 actgaggcct tgcactagca aggtcttttc tttatctggt ccccttaaaa tttaaggagg
    16141 aaaagttatg aatcccacat gtaagaagcg tttgggtgtc attcggttgg aaaccatgaa
    16201 ggtggttgca caagaggaaa tcgcgccagc aatctttgaa ttagtcctag aaggagaaat
    16261 ggttgaagcc atgcgagcag gccaatttct tcatctgcgt gtaccagacg atgcccatct
    16321 tttacgtcgt cctatttcaa tttcgtctat tgacaaggca aacaagcagt gtcacctcat
    16381 ttatcggatt gagggagctg ggactgcaat tttttcaacc ttaagtcagg gagacactct
    16441 tgatgtgatg gggcctcagg gaaatggttt tgacttgtct gaccttgatg agcagaatca
    16501 ggttctcctt gttggtggtg ggattggtgt tccacccttg cttgaggtgg ccaaggaatt
    16561 gcatgaacgt ggagtgaaag tagtgacagt cctcggtttt gctaataagg atgctgttat
    16621 tttgaaaacg gaattggctc agtatggtca ggtctttgta acgacagatg atggttctta
    16681 tggcatcaag ggaaatgttt ccgttgttat caatgattta gatagtcagt ttgatgctgt
    16741 ttactcgtgt ggggctccag gaatgatgaa gtatatcaat caaacctttg atgatcaccc
    16801 aagagcctat ttatctctgg aatctcgtat ggcttgtggg atgggagctt gctatgcctg
    16861 tgttctaaaa gtaccagaaa gcgagacggt caaccaacgc gtctgtgaag atggtcctgt
    16921 tttccgcaca ggaacagttg tattataagg agaaaattat gactacaaat cgattacaag
    16981 tgtctctacc tggtttggat ttgaaaaatc cgattattcc agcatcaggt tgttttggct
    17041 ttggacaaga gtatgccaag tactatgatt taaacctttt aggttctatt atgatcaagg
    17101 cgacaaccct tgaaccacgt tttgggaacc caactccaag agtagcagag acgcctgctg
    17161 gtatgctcaa tgcaattggc ttgcaaaatc ctggtttaga ggttgttttg gctgaaaagc
    17221 taccttggct ggaaagagaa tatccaaatc ttcctattat tgccaatgta gctggttttt
    17281 caaaacaaga gtatgcagct gtttctcatg ggatttccaa ggcaactaat gtaaaagcta
    17341 tcgagctcaa tatttcttgt cccaatgttg accactgtaa tcatggactt ttgattggtc
    17401 aagatccaga tttggcttat gatgtggtga aagcagctgt ggaagcctca gaagtgccag
    17461 tttatgtcaa attaaccccg agtgtgaccg atatcgttac tgtcgcaaaa gctgcagaag
    17521 atgcgggagc aagtggcttg accatgatca atactctggt tggaatgcgc tttgacctca
    17581 aaaccagaaa accaatcttg gccaatggaa caggtggaat gtcaggtcca gcagtctttc
    17641 cagtagccct caaactcatc cgccaagtag cccaaacaac agacctgcct atcattggaa
    17701 tggggggagt ggattcggct gaagctgccc tagaaatgta tctggctggg gcatctgcta
    17761 tcggagttgg aacagctaac tttaccaatc cttatgcctg ccctgacatc atcgaaaatt
    17821 taccaaaagt catggataaa tacggtatta gcagtctgga agaactccgt caggaagtaa
    17881 aagagtctct gaggtaaact gcaatcaatc tgttcttgat tttttattag tttgtaatat
    17941 gaatttagga gaattttggt acaataaaat aaataagaac agaggaagaa ggttaatgaa
    18001 gaaagtaaga tttatttttt tagctctgct atttttctta gctagtccag agggtgcaat
    18061 ggctagtgat ggtacttggc aaggaaaaca gtatctgaaa gaagatggca gtcaagcagc
    18121 gaatgagtgg gtttttgata ctcattatca atcttggttc tatataaaag cagatgctaa
    18181 ctatgctgaa aatgaatggc taaagcaagg tgacgactat ttttacctca aatctggtgg
    18241 ctatatggcc aaatcagaat gggtagaaga caagggagcc ttttattatc ttgaccaaga
    18301 tggaaagatg aaaagaaatg cttgggtagg aacttcctat gttggtgcaa caggtgccaa
    18361 agtaatagaa gactgggtct atgattctca atacgatgct tggttttata tcaaagcaga
    18421 tggacagcac gcagagaaag aatggctcca aattaaaggg aaggactatt atttcaaatc
    18481 cggtggttat ctactaacaa gtcagtggat taatcaagct tatgtgaatg ctagtggtgc
    18541 caaagtacag caaggttggc tttttgacaa acaataccaa tcttggtttt acataaaaga
    18601 aaatggaaac tatgctgata aagaatggat tttcgagaat ggtcactatt attatctaaa
    18661 atctggtggc tacatggcag ccaatgaatg gatttgggat aaggaatctt ggttttatct
    18721 caaatttgat gggaaaatag ctgaaaaaga atgggtctac gattctcata gtcaagcctg
    18781 gtactacttc aaatccggtg gttacatgac agccaatgaa tggatttggg ataaggaatc
    18841 ttggttttac ctcaagtctg atggcaaaat ggctgaaaaa gaatgggtct acgattctca
    18901 tagtcaagcc tggtactact tcaaatctgg tggttacatg gcgaaaaatg agacagtaga
    18961 tggttatcag cttggaagcg atggtaaatg gcttggagga aaagctacaa atgaaaatgc
    19021 tgcttactat caagtagtgc ctgttacagc caatgtttat gattcagatg gtgaaaagct
    19081 ttcctatata tcgcaaggta gtgtcgtatg gctagataag gatagaaaaa gtgatgacaa
    19141 gcgcttggct attactattt ctggtttgtc aggctatatg aaaacagaag atttacaagc
    19201 gctagatgct agtaaggact ttatccctta ttatgagagt gatggccacc gtttttatca
    19261 ctatgtggct cagaatgcta gtatcccagt agcttctcat ctttctgata tggaagtagg
    19321 caagaaatat tattcggcag atggcctgca ttttgatggt tttaagcttg agaatccctt
    19381 ccttttcaaa gatttaacag aggctacaaa ctacagtgct gaagaattgg ataaggtatt
    19441 tagtttgcta aacattaaca atagcctttt ggagaacaag ggcgctactt ttaaggaagc
    19501 cgaagaacat taccatatca atgctcttta tctccttgcc catagtgccc tagaaagtaa
    19561 ctggggaaga agtaaaattg ccaaagataa gaataatttc tttggcatta cagcctatga
    19621 tacgacccct tacctttctg ctaagacatt tgatgatgtg gataagggaa ttttaggtgc
    19681 aaccaagtgg attaaggaaa attatatcga taggggaaga actttccttg gaaacaaggc
    19741 ttctggtatg aatgtggaat atgcttcaga cccttattgg ggcgaaaaaa ttgctagtgt
    19801 gatgatgaaa atcaatgaga agctaggtgg caaagattag tactataagt gaatatgatt
    19861 tgagtgaata gtaagttaaa aatcctgatt tcaagtaaaa tcaggatttt ttcatggatg
    19921 caattttttt ggagtctggt gtgacgcgga gggtcttttg tcctgtgtaa gtgacaaagc
    19981 cgggttttcc accagttggt ttattgagtt ttttgacttc aatcatatct acctgcacca
    20041 gattcgacag gcgcccttga gagaagtagg cagctaactc tgctgcgtct gtcttgactg
    20101 catcagatgg gtcaagattt cctgagatga caacatggct tccaggaatg tccttagcat
    20161 ggaaccaaag ttcctccttg cgggccattt taaaggtcaa ttcctcattt tgaagattgt
    20221 ttcgtccgac atagatgatg gttttgccat cgcttgctag atattgttct agttttttgc
    20281 gtttctggat tttctcccgt tgtcttctgc ggataaaacc tgtttgaatc aattcttcac
    20341 ggatttcagc gatttcttcc agtccagctt ggttgaggac ggtttctaca ctttccagat
    20401 agagaatagt ggctttggtt tcttcaatca aatcagtcaa gtatttgaca gcttctttga
    20461 gtttctgata ccgtttaaaa tagcgttggg cattctggtt gggagtcaga gccttatcaa
    20521 gcgcaatcat gataggttgg ttggtatagt agttgtctag gataacctgg tcttggtcgt
    20581 taggcacttg gtggaggaag gttgtcagca attctccttt ttgacgaaat tcttcagcgt
    20641 tgtctgtcgc cagtaactct ttttcctgtt ttttgagttt gtgtcggttt ttctgaagtt
    20701 cattttcaac acgacgaatc agttcactgg cctgctgttt gacgcggtcg cgctcagcct
    20761 tatccttata gtaggtgtcc aacaaatcag aaagatttgc aagaggctct cccacctgat
    20821 ttgcaaaagg aactggactg aaggaagtct cagtcaagca tggcttggtt tcttgattga
    20881 aaaaatttcg gaaagcggaa agtttttcac taaccagtat cctttccaat tcatttgccg
    20941 tatcgcgtcc cagaccttga aagaggcttt gaagattttt tgctgttagt tcttgggttt
    21001 gcaggatttc aaagagcttt tcatccttga tagtaaaagg attgagagat tttgtacttg
    21061 gcggagcgat ataggtcgat cctggaagta aggtgcggta gctattttgt gaaaagccga
    21121 cgtgtttgat aacttcgagg attttatgac tgcttttatc gaccagtaga atattactgt
    21181 gtttccccat aatttcgata atcaaggtag cctggatatg gtctccaatc tcgtttttat
    21241 tggaaactgt aatttccaca atacggtcat tttccacttg ctcaatcgac tcaatcaggg
    21301 ccccctgcaa atactttctc aaaaccatga taaaggtaga aggttgggct ggattttcaa
    21361 aagtcgtttg ggtcagctga atgcgtccaa aaactggatg ggcagaaagg agcaggcgat
    21421 ggctttggcg attgctgcgg atttgcaaga ccaactcttg ttcaaaaggc tgattgattt
    21481 tctggatgcg accattcact aattcgcttc gcaattcctc aactatgtgg tgtaaaaaaa
    21541 atccgtcaaa tgacatcgtt ctctccttgt gattgtattc catagtatta tatcaaaaag
    21601 gtagaataaa atcatggaaa tgtggtataa taaagccaag taaagagaaa cgagaagcac
    21661 atgtatattg aaatggtaga tgaaactggt caagtttcaa aagaaatgtt gcaacaaacc
    21721 caagaaattt tggaatttgc agcccaaaaa ttaggaaaag aagacaagga gatggcagtc
    21781 acttttgtga ccaatgagcg tagtcatgaa cttaatctgg ggtaccgtga caccgaccgt
    21841 ccgacagatg tcatcagcct tgagtataaa ccagaattgg aaattgcctt tgacgaagag
    21901 gatttgcttg aaaatccaga attggcagag atgatgtctg agtttgatgc ctatattggg
    21961 gaattgttca tctctatcga taaggctcat gagcaggccg aagaatatgg tcacagcttt
    22021 gagcgtgaga tgggcttctt ggcagtacac ggctttttac atattaacgg ctatgatcac
    22081 tatactccgg aagaagaagc ggagatgttc ggtttacaag aagaaatttt gacagcctat
    22141 ggactcacaa gacaataaac gaaaatggaa aaatcgtgac ctgatatcca gtttagaatt
    22201 tgccatcaca gggattttta ctgctatcaa ggaagaacgc aatatgcgaa aacatgcagt
    22261 gacggctcta gtggtcatcc ttgcaggttt tggttttcag gtgtcacgaa tcgaatggct
    22321 ctttctccta ttgagcattt tcttggtggt agcctttgaa attatcaatt ctgctatcga
    22381 aaatgtggtg gatttggcca gtcactatca cttttccatg ctggctaaaa atgccaagga
    22441 tatggcggct ggcgcggtat tagtggtttc tctttttgca gccttaacag gcgcattgat
    22501 ttttctccca cgaatctggg atttattatt ttaaacagta agaggaaatt atgactttta
    22561 aatcaggctt tgtagccatt ttaggacgtc ccaatgttgg gaagtcaacc tttttaaatc
    22621 acgttatggg gcaaaagatt gccatcatga gtgacaaggc gcagacaacg cgcaataaaa
    22681 tcatgggaat ttacacgact gataaggagc aaattgtctt tatcgacaca ccagggattc
    22741 acaaacctaa aacagctctc ggagatttca tggttgagtc tgcctacagt acccttcgcg
    22801 aagtggacac tgttcttttc atggtgcctg ctgatgaagc gcgtggtaag ggggacgata
    22861 tgattatcga gcgtctcaag gctgccaagg ttcctgtgat tttggtggtg aataaaatcg
    22921 ataaggtcca tccagaccag ctcttgtctc agattgatga cttccgtaat caaatggact
    22981 ttaaggaaat tgttccaatc tcagcccttc agggaaataa cgtgtctcgt ctagtggata
    23041 ttttgagtga aaatctggat gaaggtttcc aatatttccc gtctgatcaa atcacagacc
    23101 atccagaccg tttcttagtt tcagaaatgg ttcgcgagaa agtcttgcac ctaactcgtg
    23161 aagagattcc gcattctgta gcagtagttg ttgactctat gaaacgagac gaagagacag
    23221 acaaggttca catccgtgca accatcatgg tcgagcgcga tagccaaaaa gggattatca
    23281 tcggtaaagg tggcgctatg cttaagaaaa tcggtagcat ggcccgtcgt gatatcgaac
    23341 tcatgctagg agacaaggtc ttcctagaaa cctgggtcaa ggtcaagaaa aactggcgcg
    23401 ataaaaagct agatttggct gactttggct ataatgaaag agaatactaa gtagaggtgg
    23461 gctcatgcct gcttcttgtt tttacagaag gaggacttat gcctgaatta cctgaggttg
    23521 aaaccgtttg tcgttgctta gaaaaattga ttataggaaa gaagatttcg agtatagaaa
    23581 ttcgctaccc caagatgatt aagacggatt tggaagagtt tcaaagggaa ttgcctagtc
    23641 agattatcga gtcaatggga cgtcgtggaa aatatttgct tttttatctg acagacaagg
    23701 ttttgatttc ccatttgcgg atggagggca agtattttta ctatccagac caaggacctg
    23761 aacgcaagca tgcccatgtt ttctttcatt ttgaagatgg tggcacgctt gtttatgagg
    23821 atgttcgcaa gtttggaacc atggaactct tggtgcctga ccttttagac gcctacttta
    23881 tttctaaaaa attaggtcct gaaccaagcg aacaagactt tgatttacag gtctttcaat
    23941 ctgcccttgc caagtccaaa aagcctatca aatcccatct cctagaccag accttggtag
    24001 ctggacttgg caatatctat gtggatgagg ttctctggcg agctcaggtt catccagcta
    24061 gatcttccca gactttgaca gcagaagaag cgacagctat tcatgaccaa accattgctg
    24121 ttttgagcca ggctgttgaa aaaggcggtt ccaccattcg gacctatacc aatgcctttg
    24181 gggaagatgg aagcatgcag gattttcatc aggtctatga taagactggt caaggatgtg
    24241 tacgctgtgg taccatcatt gagaaaattc aactaggtgg acgtggaacc cacttttgtc
    24301 caaactgtca aaggagggac tgatgggaaa aatcatcgga atcactgggg gaattgcctc
    24361 tggtaagtca actgtgacaa attttctaag acagcaaggc tttcaagtag tggatgccga
    24421 cgcagtcgtc caccaactac agaaacctgg tggtcgtctg tttgaggctc tagtacagca
    24481 cttttggcaa gaaatcattc ttgaaaacgg agaactcaat cgccctctcc tagctagtct
    24541 catcttttca aatcctgatg aacgagaatg gtctaagcaa attcaagggg agattatccg
    24601 tgaggaactg gctactttga gagaacagtt ggctcagaca gaagagattt tcttcatgga
    24661 tattccccta ctttttgagc aggactacag cgattggttt gctgagactt ggttggtcta
    24721 tgtggaccga gatgcccaag tagaacgctt aatgaaaagg gaccagttgt ccaaagatga
    24781 agctgagtct cgtctggcag cccagtggcc tttagaaaaa aagaaagatt tggccagcca
    24841 ggttcttgat aataatggca atcagaacca gcttcttaat caagtgcata tccttcttga
    24901 gggaggtagg caagatgaca gagattaact ggaaggataa tctgcgcatt gcctggtttg
    24961 gtaattttct gacaggagcc agtatttctt tggttgtacc ttttatgcct atcttcgtgg
    25021 aaaatctagg tgtagggagt gagcaagtcg ctttttatgc aggcttagca atttctgtct
    25081 ctgctatttc cgcggcgctc ttttctccta tttggggtat tcttgctgac aaatacggcc
    25141 gaaaacccat gatgattcgg gcaggtcttg ctatgactat cactatggga ggcttggcct
    25201 ttgtcccaaa tatctattgg ttaatctttc ttcgtttact aaacggtgta tttgcaggtt
    25261 ttgttcctaa tgcaacggca ctgatagcca gtcaggttcc aaaggagaaa tcaggctctg
    25321 ccttaggtac tttgtctaca ggcgtagttg caggtactct aactggtccc tttattggtg
    25381 gctttatcgc agaattattt ggcattcgta cagttttctt actggttggt agttttctat
    25441 ttttagctgc tattttgact atttgcttta tcaaggaaga ttttcaacca gtagccaagg
    25501 aaaaggctat tccaacaaag gaattattta cctcggttaa atatccctat cttttgctca
    25561 atctcttttt aaccagtttt gtcatccaat tttcagctca atcgattggc cctattttgg
    25621 ctctttatgt acgcgattta gggcagacag agaatcttct ttttgtctct ggtttgattg
    25681 tgtccagtat gggcttttcc agcatgatga gtgcaggagt catgggcaag ctaggtgaca
    25741 aggtgggcaa tcatcgtctc ttggttgtcg cccagtttta ttcagtcatc atctatctcc
    25801 tctgtgccaa tgcctctagc ccccttcaac taggactcta tcgtttcctc tttggattgg
    25861 gaaccggtgc cttgattccc ggggttaatg ccctactcag caaaatgact cccaaagccg
    25921 gcatttcgag ggtctttgcc ttcaatcagg tattctttta tctgggaggt gttgttggtc
    25981 ccatggcagg ttctgcagta gcaggtcaat ttggctacca tgctgtcttt tatgcgacga
    26041 gcctttgtgt tgcctttagt tgtctcttta acctgattca atttcgaaca ttattaaaag
    26101 taaaggaaat ctagtgcgag taaaaattaa tctcaaatgc tcctcttgtg gcagtatcaa
    26161 ttacctaacc agtaaaaatt caaaaaccca tccagacaag attgaggttt taaagtattg
    26221 tcccaaggaa agaaaagtaa ccctacatct tgaatctaag tagattttat ggtaaaataa
    26281 tagggatttt aaggagtttg atatgtataa cctattatta accattttat tagtattatc
    26341 tgttgtgatt gtgattgcaa ttttcatgca accaaccaaa aaccaatcca gcaatgtatt
    26401 tgatgccagt tcaggtgatt tgtttgaacg tagtaaagct cgcggttttg aagctgtaat
    26461 gcagcgtttg acagggattt tagtcttttt ctggctagcc attgccttag cattgacggt
    26521 attatcaagt agataagaaa ataatgggca ggactaggtc tttgcctctt tttattttta
    26581 aaggatgttt gagaaggttt tacagtaaaa gaaaattaaa aaatctagaa agaaaatatg
    26641 aaagatagaa taaaagaata tttacaagac aagggaaagg tgactgttaa tgatttggct
    26701 caggctttgg gaaaagacag ttccaaggat tttcgtgagt tgattaaaac cttgtcctta
    26761 atggaaagaa agcaccaaat tcgttttgaa gaagatggta gtctgacatt agaaattaag
    26821 aaaaaacatg agattaccct caaggggatt tttcatgccc ataaaaatgg ctttggcttt
    26881 gttagtctgg aaggcgagga ggacgacctt tttgtaggga aaaatgatgt caactatgct
    26941 attgatggtg ataccgtcga ggtagtgatt aagaaagtcg ctgaccgcaa taagggaaca
    27001 gcagcagaag ccaaaattat tgatatccta gaacacagtt tgacaacagt tgtcgggcaa
    27061 atcgttctgg atcaggaaaa acctaagtat gctggctata ttcgttcaaa aaatcagaaa
    27121 atcagtcaac cgatttatgt taagaaacca gccctaaaat tagaaggaac agaagttctc
    27181 aaagtcttta tcgataaata cccaagcaag aaacatgatt tctttgtcgc gagtgttctc
    27241 gatgtagtgg gacactcaac ggatgtcgga attgatgttc ttgaggtctt ggaatcaatg
    27301 gacattgtat ccgagtttcc agaagctgtt gttaaggaag cagaaagtgt gcctgatgct
    27361 ccgtctcaaa aggatatgga aggtcgtctg gatctaagag atgaaattac ctttaccatt
    27421 gacggtgcgg atgccaagga cttggacgat gcagtgcata tcaaggctct gaaaaatggc
    27481 aatctggagc ttggggttca catcgcagat gtttcttatt atgtgaccga ggggtctgcc
    27541 cttgacaagg aagcccttaa ccgtgcgact tctgtttacg tgacagaccg agtggtgcca
    27601 atgcttccag aacgactatc aaatggcatc tgctctctca atccccaagt tgaccgcctg
    27661 acccagtctg ctattatgga gattgataaa catggtcgtg tggtcaacta taccattaca
    27721 caaacagtta tcaagaccag ttttcgtatg acctatagcg atgtcaatga tatcctagct
    27781 ggcgatgaag aaaagagaaa agaatatcat aaaattgtat caagtatcga actcatggcc
    27841 aagcttcatg aaactttaga aaacatgcgt gtgaaacgtg gagctctcaa ttttgatacc
    27901 aatgaagcga agattttagt ggataaacaa ggtaagcctg ttgatatcgt tcttcggcag
    27961 cgtggtattg ccgagcggat gattgagtct tttatgttga tggctaatga aacagttgcc
    28021 gaacatttca gcaagttgga tttgcctttt atctatcgaa ttcacgagga gcctaaggct
    28081 gaaaaggttc agaagtttat tgattatgct tcgagttttg gcttgcgcat ttatggaact
    28141 gccagtgaga ttagtcagga ggcacttcaa gacatcatgc gtgctgttga gggagaacct
    28201 tatgcagatg tattgtccat gatgcttctt cgctctatgc agcaggctcg ttattcggag
    28261 cacaatcacg gccactatgg actagctgct gactattata ctcactttac cagtccaatt
    28321 cgtcgttatc cagaccttct tgttcaccgt atgattcggg attacggccg ttctaaggaa
    28381 atagcagagc attttgaaca agtgattcca gagattgcga cccagtcttc caaccgtgaa
    28441 cgtcgtgcca tagaagctga gcgtgaagtc gaagccatga aaaaggctga gtatatggaa
    28501 gaatacgtgg gtgaagagta tgatgcagtt gtatcaagta ttgtcaaatt cggtctcttt
    28561 gtcgaattgc caaacacagt tgaaggcttg attcacatca ctaatctacc tgaattttat
    28621 catttcaatg agcgtgattt gactcttcgt ggagaaaaat caggtatcac tttccgagtg
    28681 ggtcagcaga tccgtatccg tgttgaaaga gcggataaaa tgactggaga gattgatttt
    28741 tcattcgtac ctagtgagtt tgatgtgatt gaaaaaggct tgaaacagtc tagtcatagt
    28801 ggcagagggc gtggttcaaa tcgtcgttcg gataagaagg aagacaagag aaaatcagga
    28861 cgctcaaatg ataagcgtaa gcattcacaa aaagacaaga agaaaaaagg aaagaaacct
    28921 ttttacaagg aagtagctaa gaaaggagcc aagcatggca aagggcgagg gaaaggtcgt
    28981 cgcacaaaat aaaaaggcac gccacgacta tacaatcgta gatacgctag aggcagggat
    29041 ggtcctgact ggaactgaaa tcaagagtgt acgagctgct cgaattaatc tcaaggatgg
    29101 ctttgctcaa gtgaaaaatg gagaagtttg gctgagcaat gttcatatcg cgccttacga
    29161 agagggcaat atctggaacc aggaaccaga acgtcgtcgt aaactcctgc tccataaaaa
    29221 gcaaattcaa aaattggaac aagagaccaa agggacagga atgaccttag ttccccttaa
    29281 ggtctatata aaagatggct acgctaagct tcttttagga cttgccaaag ggaagcatga
    29341 ctatgacaaa cgggagtcta tcaaacgtcg tgagcaaaat cgagatatcg cgcgtgtgat
    29401 gaaagctgtt aatcagcgat aaaaagagga attgaaaatg gaaaaattag ttgcctataa
    29461 acgcatgcct ttgtggaata aacaaacaat gcctgaagat gttcagcaaa agcacaatac
    29521 aaaagttggg acttggggga aaattactgt cttgaaggga gctctcaagt ttattgaatt
    29581 gacagaagaa ggggaagttc tagctgaaca cctctttgaa gcaggggcag acaatccaat
    29641 ggcccaacct caagcctggc accgagtgga agctgccaca gatgatgtgg aatggtactt
    29701 ggaattttat tgtaaacctg aggattattt tgctaaaaaa tacaatacca atcctgttca
    29761 ttcagaggtc ctagaggcca tgcagacagt gaaacaaggg aaagctttgg atttgggttg
    29821 tggtcagggg cgtaattctc tttttctagc ccagcaagat tttgatgtga cggctgtaga
    29881 tcaaaatgga ctagctcttg aaatcttgca aagcattgtg gagcaggaag atttggacat
    29941 gcctgttggc ctttacgata tcaattcagc tagcattgaa caagaatatg attttatcgt
    30001 ttcaacagtt gttctcatgt ttctacaagc ggaccgcatt ccagctatta ttcaaaatat
    30061 gcaggagaaa accagtgttg gtggttacaa ccttatcgtt tgtgccatgg acacggagga
    30121 ttatccttgc tcggttaatt tcccattcac ctttaaagaa ggagaactgg cagactatta
    30181 caaggattgg gaattggtta agtacaatga aaatccaggc catttgcacc gtcgcgatga
    30241 gaatggcaat cgtattcaac tacgctttgc gaccttacta gctaagaaaa tcaagtaaac
    30301 acacatgaag attaggaatt ttcctgatct tttttctttt ttacgaatga tatagaaaag
    30361 gagggaattc atgtttgttg cgagagatgc taggggagaa ttggtaaatg tgttagagga
    30421 taaacttgag aagcaagcat acacctgccc agcttgtgga ggccagctcc atttgcgtca
    30481 aggaccaagt gtacggacgc attttgccca taaatcctta aaagactgtg attttttctt
    30541 tgaaaatgaa agtccagaac acctggccaa taaggaatcc ctctatcact ggttgaaaaa
    30601 agagacaaag gttcaattag agtacccgct ttcagaactt aaacagattg cggatgtatt
    30661 tgtaaatggc aatctagctc tagaagttca gtgtagtccc ttgcctcaga aagtccttaa
    30721 agagcgaagt gagggatatc gtagtcaggg ttaccaagta ctgtggttgc tgggtcaaaa
    30781 actgtggctc aaggagcgtt tgactcgtct acagcaaggt tttctttatt tcagtcaaaa
    30841 catgggcttt tatgtttggg aattagacaa ggaaaaacaa gttttaagac tcaaatacct
    30901 gatttaccag gatctccgcg gtaaactcca ttatcaaatc aaggaatttt cctatggtca
    30961 aggta
//
LOCUS       DAVBIC010000025        30074 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.025, whole genome shotgun sequence.
ACCESSION   DAVBIC010000025 DAVBIC010000000
VERSION     DAVBIC010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30074)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30074)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30074
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.025"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            51..1100
                     /locus_tag="VQ664_001091"
     CDS             51..1100
                     /locus_tag="VQ664_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HET2789261.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVGLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SNGRAEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLDLLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYRE
                     IGSEAVHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLEQVGSNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHLPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            complement(1200..5042)
                     /gene="spuA"
                     /locus_tag="VQ664_001092"
     CDS             complement(1200..5042)
                     /gene="spuA"
                     /locus_tag="VQ664_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HET2789262.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNESDISSPGNANASLEKTEEKPAASPA
                     DPAPQTGQDRSSEPTTSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQGLWTWDD
                     VEKPSENWPNGALSFKDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVE
                     KLVPKMNEAWLDQDYKVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVKNPSSAQW
                     PDGTDFTATGKYGRYIDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFTDLKNHSQ
                     IFLKDDDESIYTNPYYVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKHSNITNHL
                     GNKVTITDVAIDEAGKKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWRLKDETYSYDGK
                     LGADLKEEGKQVDLTLWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTWKQTLDST
                     NKLGITDFTGYYYQYQIERQGKTVLALDPYAKSLAAWNSDDSKIDDAHKVAKAAFVDP
                     AKLGPQDLTYGKIHNFKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDY
                     LKDLGVTHIQLLPVLSYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSLTGMYSSD
                     PKNPEKRIAEFKNLINEIHKRGMGAILDVVYNHTAKVDLFEDLEPNYYHFMDADGTPR
                     TSFGGGRLGTTHHMTKRLLIDSIKYLVDTYKVDGFRFDMMGDHDAASIEEAYKAARAL
                     NPNLIMLGEGWRTYAGDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPA
                     FITGGKRDVNTIFKNLIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKA
                     ENYAEIHRRLRLGNLMVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDKVPNKSHL
                     LRDKDGNPFDYPYFIHDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQS
                     TDAFRLKSLQDIKDRVHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVNADEKARE
                     FNLGTAFAHLRNAEVLADENQAGSVGIANPKGLEWTEKGLKLNALTATVLRVSQNGTS
                     HESTAEEKPDSTPSKPEHQNEASHPEHQDPAPEARPDSTKPDTKVADAENKPSQATAD
                     SQAEQPAQEAQASSVKEAVRNESVENSSKKNIPATPDRQAELPNTGIKNENKLLFAGI
                     SLLALLGLGFLLKNKKEN"
     gene            5459..5872
                     /gene="rpsL"
                     /locus_tag="VQ664_001093"
     CDS             5459..5872
                     /gene="rpsL"
                     /locus_tag="VQ664_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HET2789263.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            5892..6362
                     /gene="rpsG"
                     /locus_tag="VQ664_001094"
     CDS             5892..6362
                     /gene="rpsG"
                     /locus_tag="VQ664_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HET2789264.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            6787..8868
                     /gene="fusA"
                     /locus_tag="VQ664_001095"
     CDS             6787..8868
                     /gene="fusA"
                     /locus_tag="VQ664_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HET2789265.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLIEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEEIRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEK
                     AKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLSLKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            8972..13363
                     /locus_tag="VQ664_001096"
     CDS             8972..13363
                     /locus_tag="VQ664_001096"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HET2789266.1"
                     /translation="MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKARSQEFSNQLLQSYYREAFSEGP
                     CASQGFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VEKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPAFDFQAKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDLQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGMEANIVEDRVPIVYNEVEMDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNATFDVGFMNANYERHDLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVD
                     AAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFESVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNKIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEVIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYRSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            13465..13728
                     /locus_tag="VQ664_001097"
     CDS             13465..13728
                     /locus_tag="VQ664_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HET2789267.1"
                     /translation="MSKMSISIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQALTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            13721..13999
                     /locus_tag="VQ664_001098"
     CDS             13721..13999
                     /locus_tag="VQ664_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HET2789268.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPARY
                     RDHSLTASKHFQGVRECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            14020..14172
                     /locus_tag="VQ664_001099"
     CDS             14020..14172
                     /locus_tag="VQ664_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789269.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGIF
                     SALKEK"
     gene            14194..15435
                     /locus_tag="VQ664_001100"
     CDS             14194..15435
                     /locus_tag="VQ664_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HET2789270.1"
                     /translation="MVLPNFKENLGKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDFLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEEFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFKNAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            15445..15675
                     /locus_tag="VQ664_001101"
     CDS             15445..15675
                     /locus_tag="VQ664_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HET2789271.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAILGAMIVLAIFWRRGS"
     gene            15898..16620
                     /locus_tag="VQ664_001102"
     CDS             15898..16620
                     /locus_tag="VQ664_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HET2789272.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DIDTHGLLLLTNNGQLAHVLLSPKRHVDKTYQAQVKGIMTQEDVETFIKGIPLKDFTC
                     QPARLEILSTDAEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILRANII"
     gene            16837..18171
                     /gene="pepC"
                     /locus_tag="VQ664_001103"
     CDS             16837..18171
                     /gene="pepC"
                     /locus_tag="VQ664_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HET2789273.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALECRQSH
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAILNKLLRQDAQILRDLLVSGADQATVQAKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAE"
     gene            complement(18227..19138)
                     /locus_tag="VQ664_001104"
     CDS             complement(18227..19138)
                     /locus_tag="VQ664_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET2789274.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(19162..19965)
                     /locus_tag="VQ664_001105"
     CDS             complement(19162..19965)
                     /locus_tag="VQ664_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HET2789275.1"
                     /translation="MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            complement(19993..20982)
                     /gene="manX"
                     /locus_tag="VQ664_001106"
     CDS             complement(19993..20982)
                     /gene="manX"
                     /locus_tag="VQ664_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HET2789276.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQTAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
     gene            complement(21215..22234)
                     /gene="adhP"
                     /locus_tag="VQ664_001107"
     CDS             complement(21215..22234)
                     /gene="adhP"
                     /locus_tag="VQ664_001107"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HET2789277.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKV
                     EPGQWVVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLTLAKEVGADIVINGLEVE
                     DVAGLIKEKTDGGAHSAVVTAVSKVAFNQAVDSIRAGGRVVAVGLPSEMMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVVPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
     gene            complement(22573..23385)
                     /locus_tag="VQ664_001108"
     CDS             complement(22573..23385)
                     /locus_tag="VQ664_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET2789278.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKRTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKEMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            23575..24993
                     /locus_tag="VQ664_001109"
     CDS             23575..24993
                     /locus_tag="VQ664_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HET2789279.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLIITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHAMIWILDALFILNYISMAL"
     gene            25046..25753
                     /locus_tag="VQ664_001110"
     CDS             25046..25753
                     /locus_tag="VQ664_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2789280.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLIVTGLSIVVLALFIMGARKTKLASFNFSFFRAKDLARLGLSYLVIVGSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGIVPKKIFRGKE
                     NLGFVVGTIVFALLHQPSNLPSLLIYGGMSTVLSWTAYKTQRLEMSILLHMIVNGIAF
                     CLLALVVIMSRTLGISV"
     gene            25848..26822
                     /gene="folP"
                     /locus_tag="VQ664_001111"
     CDS             25848..26822
                     /gene="folP"
                     /locus_tag="VQ664_001111"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HET2789281.1"
                     /translation="MMKILEGVTDMSSKANHAKTVICGIINVTPDSFSDGGQFFALEQ
                     ALQQARKLIAEGASMLDIGGESTRPGSSYVEIEEEIQRVVPVIKAIRKESDVLISIDT
                     WKSQVAEAALAAGANLVNDITGLMGDEKMAHVVAKAGAKVVIMFNPVMARPQHPSSLI
                     FPHFGFGQTFTEKELADFETLPIEDLMVAFFERALARAAEAGITPENILLDPGIGFGL
                     TKKENLLLLRDLDKLHQKGYPIFLGVSRKRFVINILEESGFEVNPETELGFRNRDTAS
                     AHVTSIAARQGVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            26824..28146
                     /locus_tag="VQ664_001112"
     CDS             26824..28146
                     /locus_tag="VQ664_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HET2789282.1"
                     /translation="MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVLHI
                     GGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYLIHYTDQISINGESISEARLEALMADY
                     QSLLEGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLEAIAEQKAGIIKQGIPLVTGRIAPEALTVIDRIAEGKDAPR
                     LAYGTDYQVRHQESVVTGEVFDYTSAVRQGRFQTSLLGLYQIENAGMAIALLDTFCQE
                     DGRELASNDFLGQALEETSWPGRLEIVSRDPLMILDGAHNPHAIKALLVTLQERFADY
                     HKEILFTCIKTKALEDMLDLLGAMPDTELTLTHFADSRATDESVLKEAAKSRNLSYQD
                     WHDFLEQNLTDKKEEKQTVRIVTGSLYFLSQVRAYLMERKNENGYTKD"
     gene            28127..28681
                     /gene="folE"
                     /locus_tag="VQ664_001113"
     CDS             28127..28681
                     /gene="folE"
                     /locus_tag="VQ664_001113"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HET2789283.1"
                     /translation="MDTQKIEAAVKMIIEAVGENANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVVIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            28724..29536
                     /gene="folK"
                     /locus_tag="VQ664_001114"
     CDS             28724..29536
                     /gene="folK"
                     /locus_tag="VQ664_001114"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HET2789284.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFEFYPLVQEMKLELKKPWA
                     PVHLSLDTCSVTIHRRKQRAFIALGSNMGDKQANLKQAIDKLRARGIYILKESSVLAT
                     EPWGGVEQDSFANQVVEVETWLPAQDLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPTLKQPIRNLYDALKK"
     gene            complement(29581..29898)
                     /locus_tag="VQ664_001115"
     CDS             complement(29581..29898)
                     /locus_tag="VQ664_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HET2789285.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMYGRETILLPEEN
                     DLF"
BASE COUNT         8527 a         5841 c         7006 g         8700 t
ORIGIN      
        1 ttagaataat ttttcaaatt gaaggacaga gatagacaag gagaatcaca atggtagaat
       61 tgggaatttc aacatttggg gaaataacgg agcttgaagg gactggacaa acttacagtc
      121 atgctgaacg cattcgccag ttggtggcag agattgagct ggctgacaag gttggtttgg
      181 acgtatatgg gattggcgag caccatcggg cggattttgc agtatcagcc ccagagattg
      241 tcctggccgc tggggcagtc aataccaaga aaatccgttt gaccagtgca gtcagcattc
      301 tgtcaagcat ggatccgatt cgtttgttcc aacagtatgc cactatcgat gctttgtcaa
      361 atggacgagc ggagattatg gctggaaggg gctctttcac ggaatctttc cctctgtttg
      421 gttatgactt gaaagactac gactctcttt ttgatgagaa attagacttg cttcagttag
      481 tcaatgaaaa gaccaagtta gactggcaag gtcgattgac tcaaacgatt gctggtaaag
      541 aagtttatcc tcgtccagtt caggacaaat tgcccttgtg gatagctaca ggtggtcatg
      601 tcgaatcaac agtgaagatt gctcaggctg gtctaccgat tgtatatgct attattggtg
      661 gtaatccacg ttattttaaa aagttgattc aggcttatcg tgagattgga agcgaagcgg
      721 tccatgctga caaagacttg aaagtgggag cccattcttg ggggtggatt gcggaagatg
      781 gtgagcaggc ggtgaaagat tatttccatc cgactaagca agtggtggat gctatttcca
      841 aagaccgtcc gcactggcag gaattgcgtt atgagcaata tttggagcag gtagggtcaa
      901 atggcgccat gtttgttggc aatccagatc aggtggccga aaaattgatt cgcatgatag
      961 aggatttagg attggaccgc ttcatgcttc atctaccgct tggttctatg cctcatgacc
     1021 aggttctgag agctattgaa ctcttcggaa cacaagttgc acccaaagta cgagcttatt
     1081 ttgctatgaa agaggcttaa taaaaaatcc taatcaagtt tattaggaca acaaatattg
     1141 tacgaaaatt aatcccccga gctataatgc ttgggggatt tttctatagg agggctagtt
     1201 tagttctctt ttttattttt tagtaagaaa ccgagaccaa ggagcgcaag gaggctgatt
     1261 cctgcaaata ggagtttgtt ttcgttttta attcctgtat ttggaagttc agcttgtcta
     1321 tctggggttg caggtatatt tttcttgcta gagttttcta ccgattcgtt tcgaaccgct
     1381 tcttttacag atgatgcttg tgcttcttgt gctggttgtt cagcttgtga atcagctgta
     1441 gcttggctag gtttattttc cgcatcagct actttggtat ctggtttagt agaatcaggt
     1501 ctagcttctg gagctggatc ttgatgttca gggtgagaag cttcattttg atgttcaggc
     1561 ttggaagggg ttgagtctgg tttctcttct gcagttgact catggctagt tccattttga
     1621 gagactcgaa gaacagtagc tgtaagggca ttcaatttca agcctttttc agtccattca
     1681 agtcctttcg ggttggcaat tccgactgat cctgcttggt tttcatctgc caaaacttcc
     1741 gcatttctta gatgtgcaaa ggcagttccc aaattaaatt cgcgagcttt ttcatccgca
     1801 ttgacaaaga ctgcgtagat atcgccgttt ggagcagtga tttgatagcc aatcactaca
     1861 tcctcttttt ccacaccatt ttggcctggg acagtgatga ggtggacacg gtctttgata
     1921 tcttgaagac tcttaagtcg gaaggcatct gtagattgac gaagggcaat caaacctttc
     1981 atatagtcac ggctcttgac attttcagga taagctttac catctgtagc cttagtccag
     2041 tcaaacttgt tgactgcatc actagaatcg taagagtcat ggatgaagta aggatagtca
     2101 aatgggttgc cgtccttatc acgcaacaag tgagatttgt ttggaacctt atcctctgct
     2161 actggagtct tgtaggctgg gtcacggaat tgtttagtac gtccatattc ctgaccggag
     2221 tggataaatg gagttccttg agctgtcaag accatgagat ttccaagtcg taaacgacgg
     2281 tggatttcag catagttctc agccttgctt gggtcttttt tgatagactg ggcaatgatg
     2341 tcaaagaggg tcaagttatc atgggctgcg atgtattgga tgacatctcc agggctgtca
     2401 gcttcaaagt tagttggttg agcaatgaga tttttaaaga tggtgttgac atcacgcttg
     2461 ccacctgtga taaaggcagg ttgaccttcg tttggataac cagatttgag gttgttacgg
     2521 atgtcatctg aaaagacagc gacagtatcg gtatgtttca tccaatcttg gtcagcagct
     2581 ttagtaggca tgttttcatc accggcatag gttctccaac cttcaccaag catgatgagg
     2641 tttggattga gggcgcgtgc agccttgtaa gcttcttcga tagaagcggc gtcatggtct
     2701 cccatcatat cgaaacggaa gccatccact ttgtaggtat caactaggta tttgatagag
     2761 tcaattagga gccgtttggt catatggtgg gttgtcccca agcgtccacc accaaagcta
     2821 gttcgaggtg tgccatcggc atccataaag tggtagtagt ttggttccaa atcttcaaag
     2881 agatcgactt tggctgtgtg gttataaacg acatctagga tagctcccat accacgtttg
     2941 tggatttcgt tgatgaggtt tttaaattct gcgattcgtt tttctggatt cttaggatcg
     3001 cttgagtaca taccagtcaa ggagaagtag ttttgagggt catatcccca gttgtagttg
     3061 ctgttgcttg aagcgtagtc agacaagcgt tcatggtttt tcaattcatt gacaaagtag
     3121 taagacaaga ctggaaggag ctggatatgg gttacaccca agtctttgag atagtctagt
     3181 ttttcaatga aggcttcaaa agtcccaaat ggtttggtca agtcttttgc aatggcagga
     3241 tctgaagtga aatcacgcac atgagcttcg tagataacgg cgtcttcacg agtcttgaaa
     3301 ttgtgaatct taccataagt caagtcttga ggtccgagtt tagctggatc tacaaaggcg
     3361 gctttagcca ctttatgggc atcgtcaatc ttggaatcgt cgctattcca agcagcaaga
     3421 gatttagcgt aaggatcgag tgcaagaaca gttttacctt gacgctcgat ttggtattga
     3481 taatagtagc cagtgaaatc tgtgattccg agtttgtttg tgctgtctag agtttgtttc
     3541 caagttcctc tttccccttt ttcaagagcg acagttccaa ctactttgtc agggtcattc
     3601 ttgtcgtaga caacaacaga aaccttatca gcacttggtg accaaagggt caaatcaact
     3661 tgttttcctt cttcttttag gtcagctccc agtttgccat catagctgta tgtctcatct
     3721 ttcaggcgcc agcttgtttt ggtagtgaat tggtcggaat tgtagctaac agtataagga
     3781 tgttttgtgt cagagaaatc tccgctgtag gtcactttct taccagcttc atcgattgca
     3841 acatcggtaa tagttacctt gtttcctagg tgattagtga tgttggagtg tttgaggata
     3901 tcttcttttt tagcaccgac aagtgttgaa aagctacttt caatgctaga agtgcctacg
     3961 tgttgggctc ctgtcatacg gatatcatgg acatagtatg gatttgtgta aatcgattca
     4021 tcatcgtctt ttaggaaaat ttggctatga tttttcaaat ctgtgaactt ataattttct
     4081 ttacggattt tcacgtcgtc tccttgtttg ctctcatcta gtaataaaaa tccaaattct
     4141 cttgcggctt cattaagagg aatgtcgata tagcggccat atttgcctgt agccgtaaag
     4201 tctgttccgt caggccattg agcgctactt ggatttttca catctcccca gtaccagaga
     4261 gatttcttgt catagttgcc atctgtgcgg tagtagttga cgcgaacagt tcctgcaggc
     4321 tgtggctcgt aagagaaaac cttgtaatct tggtctaacc aagcttcgtt catttttgga
     4381 actagttttt ctacagattt atcgccggtt agattttttc cagctgtatt gttgatgagg
     4441 aagctaattt tcttggcttg ttctcccttt aatttgacat ctaggtaata gccgtagtca
     4501 tctttcttgg catccttgaa ggacaaagct ccgtttggcc agttttcaga tggtttttca
     4561 acatcgtccc aagtccatag tccttgagca tccttgtttt cttcaggaag ttttttgaca
     4621 tggatacgga agtagttatc ttcgatgggc tcttctgcct tagtttcagt tgttactgga
     4681 ctagtagaag tagttggctc acttgaacga tcttgtccag tttgtggtgc tggatcggct
     4741 gggcttgcag caggtttttc ttctgttttc tctagggaag cgtttgcatt tccaggtgaa
     4801 gaaatatcac tttcgttctt accagagcca gctgctgtat cagtaagagg ttgggcaagg
     4861 gtggttgtat ttctgttgtt gggttcgtta gtggttggtg tactttcgtc ggatgagata
     4921 gttggtgtag ccatggcaag caagacaagg cttgcgccga taaggacaga accagttcca
     4981 tttttgaggg aacggatgct gtagaccatt tttttctcag tgtgagatgg tgtttttctc
     5041 ataatgattc tccaatcaat aaatttctat atcagtatag catgtagtaa aacaatatgc
     5101 aagcgttttc tttgatttgt gaaagaaatt cttacttttg agaagttttc cgtactattt
     5161 tatatatcag tataaatgac ggagataaaa atgtcacgta agccaagccg tgttattagg
     5221 aagatgatgt gttctcagct atttttattc agaaattgat ctctaacatt accaataaaa
     5281 aagaaaaata tcttgacaag caagggaaaa ttttgttaca ataatagacg gtacttttta
     5341 cttttggtct ctcaagagtg tacagggacg tgctgacaaa tgttgcaaaa gtacacacag
     5401 atgatatctg tcaccaagtg tatcatcacc aaaaataaaa aaacacagga gaatgtagat
     5461 gcctacaatt aaccaattgg ttcgcaaacc gcgtaaatca aaagtagaaa aatctaaatc
     5521 accagctttg aacgttggtt acaatagtca taaaaaagtt caaacaaacg tttcttcacc
     5581 acaaaaacgt ggtgttgcaa ctcgtgttgg aacaatgaca cctaaaaaac ctaactcagc
     5641 ccttcgtaaa ttcgctcgtg tacgtttgag caaccttatc gaagttactg cctacatccc
     5701 aggtatcgga cacaacttgc aagagcacag cgtggtgctt cttcgcggtg gacgtgtaaa
     5761 agaccttcca ggggtacgtt accatatcgt ccgtggtgca cttgatactg caggtgttaa
     5821 cgatcgtaaa caaggccgtt ctaaatacgg tactaaacgt ccaaaagcat aaggaaaggg
     5881 gataaagaga aatgagtcgt aaaaatagag ctccaaaacg tgacgtattg ccagatccgc
     5941 tatacaattc acaactagtt actcgtctta tcaaccgcgt tatgcttgat ggtaaacgtg
     6001 gtactgctgc ttcaatcgtt tacggtgctt ttgagcaaat caaagaagct actggcaacg
     6061 atgcacttga agtatttgaa acagctatgg aaaacatcat gcctgtactt gaagtacgtg
     6121 cacgtcgtgt tggtggttct aactaccaag tcccagttga agttcgtcca gaacgtcgta
     6181 caacacttgg acttcgttgg ttggtaacaa tcgctcgtct tcgtggtgaa cacacaatgc
     6241 aagaccgtct tgcaaaagaa atcttggatg ctgctaacaa cactggtgca gcagttaaga
     6301 aacgtgaaga tactcaccgt atggctgaag ctaaccgtgc attcgcacac ttccgttggt
     6361 aagataggat gcgaaagcgt taagaaagtc ccagagaaaa tagggaatcg aagcaggttg
     6421 cggttgcaac caatgagatt catctttttc tccagacttt tagcttgagc tcaactaaat
     6481 catgatgcta ggaacggtaa ggatgcaagg taaaaatagg aaactgacgc agtattcgac
     6541 gaatacaagg agttttatct ttttcacgca gcatcccgtt ccagctcaca tcggctaact
     6601 aactttagcc cgggttcaaa ttagctaaat cgattagtat tagctataac tcagcttacc
     6661 atctcgtaag ttgaaaccaa caatagcatg aaaacattga gaacgggtag gtcctgccta
     6721 tccgttttta ttaaaatcgt gttataatag aatagaaatc aaaaataaat aggagaaaca
     6781 aacctcatgg cacgcgaatt ttcacttgaa aaaactcgta atatcggtat catggctcac
     6841 gtcgatgccg gtaaaacaac aactactgag cgtattcttt actacactgg taaaatccac
     6901 aaaatcggtg aaactcacga aggtgcgtca caaatggact ggatggagca agagcaagaa
     6961 cgtggtatca cgatcacatc tgctgcgacg acagctcaat ggaacaacca ccgcgtaaac
     7021 atcatcgaca caccaggaca cgtggacttc acaatcgaag tacaacgttc tcttcgtgta
     7081 ttggatggtg cggttaccgt tcttgactca caatcaggtg ttgagcctca aactgaaaca
     7141 gtttggcgtc aagcaactga gtacggagtt ccacgtatcg tatttgccaa caaaatggac
     7201 aaaatcggtg ctgacttcct ttactctgta agcacacttc acgatcgtct tcaagcaaat
     7261 gcacacccaa tccaattgcc aatcggttct gaagatgact tccgtggtat cattgacttg
     7321 atcaagatga aagctgaaat ctatactaac gaccttggta cggatatcct tgaagaagac
     7381 atcccagctg aataccttga ccaagctcaa gaataccgtg aaaaattgat tgaagcagtt
     7441 gctgaaactg acgaagaatt gatgatgaaa tacctcgaag gtgaagaaat cactaacgaa
     7501 gaattgaaag ctggtatccg taaagcgact atcaacgttg aattcttccc agtattgtgt
     7561 ggttcagcct tcaaaaacaa aggtgttcaa ttgatgcttg atgcggttat cgactacctt
     7621 ccaagcccac ttgacatccc agcaatcaaa ggtattaacc cagatacaga cgctgaagaa
     7681 attcgtccag catctgacga agagccattt gcagctcttg ccttcaagat catgactgac
     7741 ccattcgtag gtcgtttgac attcttccgt gtttactcag gtgttcttca atcaggttca
     7801 tacgtattga atacttctaa aggtaaacgt gaacgtatcg gacgtatcct tcaaatgcac
     7861 gctaacagcc gtcaagaaat cgacactgtt tactcaggtg atatcgctgc tgccgttggt
     7921 ttgaaagata ctacaactgg tgactcattg acagatgaaa aagctaaaat catccttgag
     7981 tcaatcaacg ttccagaacc agttatccaa ttgatggttg agccaaaatc taaagctgac
     8041 caagacaaga tgggtatcgc ccttcaaaaa ttggctgaag aagatccaac attccgcgtt
     8101 gaaacaaacg ttgaaactgg tgaaacagtt atctcaggta tgggtgaact tcaccttgac
     8161 gtccttgttg atcgtatgcg tcgtgagttc aaagttgaag cgaacgtagg tgctcctcaa
     8221 gtatcttacc gtgaaacatt ccgcgcttct actcaagcac gtggattctt caaacgtcag
     8281 tctggtggta aaggtcaatt cggtgatgta tggattgaat ttactccaaa cgaagaaggt
     8341 aaaggattcg aattcgaaaa cgcaatcgtc ggtggtgtgg ttcctcgtga atttatccca
     8401 gcggttgaaa aaggtttggt agaatctatg gctaacggtg ttcttgcagg ttacccaatg
     8461 gttgacgtta aagctaagct ttatgatggt tcatatcacg atgtcgactc atctgaaact
     8521 gccttcaaga ttgcggcttc actttccctt aaagaagctg ctaaatcagc acaaccagct
     8581 atccttgaac caatgatgct tgtaacaatc actgttccag aagaaaacct tggtgatgtt
     8641 atgggtcacg taactgctcg tcgtggacgt gtagatggta tggaagcaca cggtaacagc
     8701 caaatcgttc gtgcttacgt tccacttgct gaaatgttcg gttacgcaac agttcttcgt
     8761 tctgcatctc aaggacgtgg tacattcatg atggtatttg accactacga agatgtacct
     8821 aagtcagtac aagaagaaat tattaagaaa aataaaggtg aagactaatc cgtcctcact
     8881 ctagaaggaa gtcacttagt ggcttccttt tgtctttaga aaatacctct aaatatggta
     8941 aaatagtaga agaataatgt gaggaaaatg aatgtcaaat agttttgaaa ttttgatgaa
     9001 tcaattgggg atgcctgctg aaatgagaca ggctcctgct ttagcacagg ccaatattga
     9061 gcgagttgtg gttcataaaa ttagtaaggt atgggagttt catttcgtat tttctaatat
     9121 tttaccgatt gaaatctttt tagaattaaa gaaaggtttg agcgaagaat tttctaagac
     9181 aggcaataaa gctgtttttg aaattaaggc tcggtctcaa gaattttcaa atcagctctt
     9241 gcagtcctac tatagggagg ctttctctga aggtccatgt gctagtcaag gttttaagtc
     9301 cctttatcaa aatttgcaag ttcgtgctga gggtaatcag ctatttattg aaggatctga
     9361 agcgattgat aaggaacatt ttaagaagaa tcatcttcct aatttagcca aacaacttga
     9421 aaagtttggt tttccaactt ttaactgtca agtcgagaag aatgatgtcc tgacccaaga
     9481 gcaggaagag gcctttcatg ctgaaaatga gcagattgtt caagctgcca atgaggaagc
     9541 gctccgtgct atggaacaac tggagcagat ggcacctcct ccagcggaag agaaaccagc
     9601 ctttgatttt caagcgaaaa aagctgcagc taaacccaag ctggataagg cggagattac
     9661 tcctatgatc gaagtgacga cagaggaaaa tcgtctggta tttgaagggg ttgtttttga
     9721 tgtggagcaa aaagtgacta gaacaggtcg tgttttaatc aactttaaaa tgacggacta
     9781 tacttcaagt ttttctatgc aaaagtgggt taaaaacgag gaagaggccc agaagtttga
     9841 cctcatcaag aagaattctt ggctccgagt tcgagggaat gtggagatga ataacttcac
     9901 acgcgatttg actatgaacg tacaggatct gcaggaagtt gttcactatg agcggaagga
     9961 tttgatgcca gaaggtgagc gtcgggttga gtttcatgct catactaaca tgtcgactat
    10021 ggatgctttg ccagaggtcg aagagattgt tgcaacagct gctaagtggg gacacaaggc
    10081 ggttgctatc acggaccatg ggaatgtcca gtcctttcca catggctata aggcggctaa
    10141 gaaagcggga atccagctga tctatgggat ggaagccaat atcgtggagg accgtgtccc
    10201 tatcgtctat aacgaagtgg agatggactt gtcagaagca acctacgtgg tctttgacgt
    10261 ggaaacgacg ggactttcag ctatctataa tgacttgatt caggttgcgg cttctaagat
    10321 gtacaagggg aatgttattg ctgaatttga tgaatttatc aatcctgggc atcccttgtc
    10381 agcctttact acagagttaa ctggaattac agatgatcat gtcaaaaatg ccaaaccact
    10441 agaacaagtt ttgcaagaat tccaagaatt ttgcaaggat acggtcctag ttgcccacaa
    10501 tgctaccttt gacgttggct ttatgaatgc taattatgag cggcatgatc ttccaaagat
    10561 tagtcagcca gttattgata cgctggagtt tgctagaaac ctctatcctg agtataaacg
    10621 ccatggtttg gggcctttga ccaagcgttt tggtgtggcc ttggaacatc accacatggc
    10681 caactacgat gcggaagcga ctggtcgtct gcttttcatc tttatcaaag aggtagcaga
    10741 aaaacatggt gtgaccgatt tagctagact caacattgat ctaatcagtc cagattctta
    10801 caaaaaagct cggatcaagc atgcgaccat ctatgtcaag aatcaggtag gtctaaaaaa
    10861 tatctttaag ctggtttcct tgtctaatac caagtatttt gaaggagtgc cacggattcc
    10921 gagaacggtt ctagatgccc atcgagaggg cttgatttta ggttcagcct gttcagaggg
    10981 tgaagttttt gacgtggtcg tttctcaagg tgtggatgcg gcggttgagg tggccaagta
    11041 ttatgatttt atcgaggtca tgccaccggc tatctatgca cccttgattg ccaaagagca
    11101 ggtcaaggat atggaggaac tccagaccat tatcaagagt ttgatagagg ttggagaccg
    11161 ccttggcaag cctgttctgg ctacgggaaa tgttcactat atcgaaccgg aagaagagat
    11221 ttatcgtgaa attatcgtcc gtagtttggg acagggtgcg atgattaatc gaactatcgg
    11281 tcatggtgaa catgcccaac cagcaccact tccaaaggct cattttcgaa cgactaatga
    11341 gatgttggat gaatttgcct ttttgggaga ggaactggct cgtaaactgg ttattgaaaa
    11401 caccaatgcc ttggcagaaa tatttgaatc cgttgaagtc gttaagggtg acttgtatac
    11461 gcctttcatc gacaaggctg aagaaacagt tgctgagttg acctataaga aagcttttga
    11521 gatttatgga aatccgctgc cagatattgt tgatttgcgg attgaaaaag aattaacatc
    11581 catactgggg aatggatttg ctgtgattta tctggcatcg cagatgctgg tgcaacgttc
    11641 taatgaacgg ggttatttgg ttggttctcg tgggtctgtc ggatctagtt tcgttgcgac
    11701 catgattggg attacggagg tcaatcctct ctctcctcac tatgtctgtg gtcagtgtca
    11761 gtacagtgag tttatcacag atggttcgta cggttcagga tttgatatgc cccataagga
    11821 ctgtccaaac tgtggtcaca aactcagtaa aaacggacag gatattccgt ttgagacctt
    11881 ccttggtttt gatggggata aggttcctga tattgacttg aacttctcgg gagaagatca
    11941 gcctagcgcc cacttggatg tgcgtgatat ctttggtgaa gaatatgcct tccgtgcggg
    12001 aacggttggt acggtagctg ccaagactgc ctatggattt gtcaagggtt acgagcgaga
    12061 ttatggcaag ttttatcgtg atgcagaagt agaacgcctc gctcaaggag cggcgggtgt
    12121 caagcggaca acaggccaac acccgggggg aatcgttgtt attccgaact acatggatgt
    12181 ctacgatttt acgcctgtcc agtatccagc agatgatgtc acggctgaat ggcagaccac
    12241 tcactttaac ttccacgata tcgatgagaa cgtcctcaaa ctcgatgtac tgggacatga
    12301 tgatccgacc atgattcgaa aacttcagga tttgtctggt attgacccta ataaaattcc
    12361 tatggatgac gaaggcgtga tggcactctt ttctgggact gatgtactag gggtaacacc
    12421 tgaacaaatt ggaacgccta cgggtatgtt ggggattcca gagtttggaa caaatttcgt
    12481 acgtggaatg gtagacgaaa cccatccgac aacctttgcg gaattgcttc agctgtctgg
    12541 tctgtcccac ggtactgacg tttggttggg gaatgctcag gatctgatta agcaaggaat
    12601 agcggaccta tcgactgtta tcggttgtcg ggacgacatc atggtttacc tcatgcatgc
    12661 gggtctggaa cctaagatgg cctttaccat tatggaacgg gtacgtaagg gtttgtggct
    12721 aaagatttca gaagaggaga gaaatggcta tatcgaagcc atgaaggcta ataaggtgcc
    12781 agagtggtat atcgaatcct gtgggaaaat taagtacatg ttccctaagg cccatgcggc
    12841 agcctacgtt atgatggcct tgcgtgtagc ttacttcaag gttcaccatc ctatttatta
    12901 ctactgtgct tacttctcca ttcgtgctaa ggcttttgat atcaagacca tgggtgcggg
    12961 cttggaggtc atcaagcgca gaatggaaga aatctctgaa aaacggaaga acaatgaagc
    13021 ctctaatgtg gaaatcgatc tctatacaac tcttgagatt gtcaatgaga tgtgggaacg
    13081 aggtttcaag tttggtaaat tagatctcta ccgtagtcag gcgacagagt tcctcatcga
    13141 cggggatacc cttatcccac catttgtagc aatggatggt ctgggagaga acgttgccaa
    13201 gcaactggtg cgggcgcgtg aagagggaga attcctctct aaaacagaac tacgcaagcg
    13261 tggtggactc tcatcaacct tggttgaaaa gatggatgag atgggtattc ttggaaatat
    13321 gccagaggat aaccagttga gtttgtttga tgagttgttt taaaaaattg cttaataatc
    13381 tattaaaaga ggctaacgta tatccaatag atttacatta gctttctttt ttgttaaaat
    13441 agtctatgga aagagggtga gagtatgtca aagatgagta taagcatccg tctggatagt
    13501 gaggttaagg agcaggccca acaggtgttt agtaatctgg gaatggatat gacaacagct
    13561 attaatattt tccttcgtca ggcaattcaa tatcagggat taccttttga tgttagacta
    13621 gacgaaaatc ggaagttgct ccaagcgtta acggatttag accaaaatcg taatatgagc
    13681 cagtcttttg aatcagtctc agatttgatg gaggacttac gtgcttaaga ttcgttatca
    13741 taaacagttt aaaaaagatt ttaagttggc tatgaagcgt ggtttgaagg cagaattatt
    13801 agaagaagtt ttgaattttc tggttcaaga aaaagaacat cctgccagat atcgtgatca
    13861 ttcattgacg gcatccaagc attttcaagg agttcgtgaa tgccataccc agccagattg
    13921 gcttttggtt tataaagtag acaagtcgga attgatttta aatttgctga ggacaggcag
    13981 tcacagtgat ttattttaat ctattttaag ggggttctca tgaaactaag aatatttgcg
    14041 gaagataagc cggctaagaa ggtatttgaa tatcaattag aacttgctga tcgtacaatt
    14101 cttctatcga cagcactctt gtcaggtgct attgctttag caggaatctt ttctgctttg
    14161 aaagaaaaat aaaaatagaa aagagaaaac agaatggttt taccaaattt taaagaaaat
    14221 ctaggaaaat atgcgaaatt gttggttgcg aacggaatta acgtgcaacc tggtcacact
    14281 ttggctctct ctattgatgt ggagcaacgt gaattggcac atctaatcgt gaaagaagct
    14341 tatgccttgg gtgcgcatga ggtcatcgtt cagtggacag atgatgtgat taaccgtgag
    14401 aaattcctcc atgccccgat ggagcgtttg gacaatgtgc cagaatacaa gattgctgag
    14461 atgaactatc ttttggagaa caaggctagc cgtcttgggg ttcgttcatc tgatccaggt
    14521 gccttgaacg gagtggacgc tgacaagctt tcagcttctg ctaaagctat gggacttgcc
    14581 atgaagccta tgcgtatcgc aactcaatct aacaaggtta gctggactgt agcagccgct
    14641 gctggacttg agtgggctaa gaaagtcttc ccaaatgctg cgagcgacga agaagcagtt
    14701 gatttccttt gggatcaaat cttcaaaact tgtcgtgtct acgaagcaga tcctgttaag
    14761 gcttgggagg aacatgcagc cattctcaag agcaaggccg atatgcttaa taaggagcaa
    14821 ttttcagccc ttcactacac agcgccagga acagatttaa cacttggttt gccaaagaac
    14881 cacgtttggg aatcagctgg tgctgtcaat gcacagggcg aagaattctt gccaaatatg
    14941 ccgacagaag aggtcttcac agcgcctgac ttccgtcgtg cagatggtta tgtcacttct
    15001 acaaaaccgc ttagctacaa cggaaatatc attgaaggca ttaaggtgac ctttaaggat
    15061 ggacaaatcg tagatatcac tgctgagaag ggtgatcagg ttatgaaaga ccttgtcttt
    15121 aaaaatgcgg gtgcgcgtgc cttgggtgaa tgtgccttgg taccagatcc aagtccaatt
    15181 tctcagtcag gcattacctt ttttaacacc cttttcgatg aaaatgcgtc aaaccacttg
    15241 gctatcggtg cagcctatgc gactagcgtt gttgatggag cggagatgag cgaagaggag
    15301 cttgaagctg cagggcttaa ccgttcagat gttcacgtag actttatgat tggttctaac
    15361 caaatggata tcgatggtat tcgtgaggat ggaacgcggg tacctctttt ccgtaatggg
    15421 aattgggcaa attaaggaga taatatgtta ggaagtatgt tcgttggtct cctagtggga
    15481 tttttagcag gtgctatgac caatcgtgga gagcgaatgg gatgttttgg aaaaatgttt
    15541 ctcggttgga tcggagcctt tctaggtcac ttgctctttg gaacttgggg gccagtttta
    15601 tcaggaacag ctattatccc agcgatttta ggagccatga ttgttttagc tattttttgg
    15661 agacgaggaa gttaatttcc taaatctgat actcaatgaa aatcaaagag caaactagga
    15721 aactagccgc aggttgctca aagcactgct ttgaggttgc agatagaact gacgaagtca
    15781 gtaacatata tacggcaagg cgacgttgac gcggtttgaa gagatttttg aagagtatga
    15841 aacgaaaagg aggttggtca ttgtactagc ctccttttga tatgatataa tagttctatg
    15901 agattagata aatttttagt tgcctgtgcg gtgggaagtc ggactgaggt caaaaacttg
    15961 ctcaaggctg ggcgcgtgac tgtaaatggt aaaaaagaaa aatcagctaa attgcagatt
    16021 gatgaaaaaa tagatgagat tcgctttgat gggcaagtgt tggagtatga agagtttgtc
    16081 tactacatga tgaacaagcc caaaggagtt atctcagcga ctgaggatcc caagcacaga
    16141 accgttctgg acttgttgga tgacttggcg cggagtaagg aagtttttcc agtaggacgc
    16201 ttggatattg acacgcatgg tcttttgctc ttgaccaata atggtcagct ggctcatgtt
    16261 cttctttcgc ccaagcgtca tgtggacaag acttatcagg ctcaggtcaa gggaattatg
    16321 acccaagaag atgtggagac atttatcaag ggcattccgc tcaaagactt tacctgtcag
    16381 cccgctagac tggagattct ttccacagat gcagaaaaga atcagagcca aatccgtgtg
    16441 accattgcag aagggaagtt tcatcagatc aagcgtatgg tgggctactg tggcaaggaa
    16501 gtggtggact tgcaacgatt gactatggga actttagtat tagatgagaa cctggaacga
    16561 ggggaatggc gtcgcttgac caaggaagaa ttagaaattc tccgcgctaa tattatttaa
    16621 tttagtttaa tactcaatga aaatcaaaga gcaaactagg aaactagccg caggctgtac
    16681 ttgagtacgg caaggcgacg ttgacgtggt ttgaagagat tttcgaagag tataaattcg
    16741 aaaaaggtga gggacaatgt cctcgccttt tatgtttttt agttgcttcc tttgtgaaaa
    16801 gagttataat agactgtaga ataaaaggag gaatctatga acgcgattca agaatcattt
    16861 actgataaac tatttgccaa ctatgaagca aatgtaaaat accaagcgat tgaaaatgct
    16921 gccagccaca acggaatttt tgcagctctg gaatgtcgcc aaagccatgt agacaacaca
    16981 cctgttttct cattggattt aaccaaggac aaggtcacta accagaaagc gtctggtcgt
    17041 tgctggatgt ttgcggctct caacaccttc cgccacaaac tcatctcgca atacaaattg
    17101 gagaactttg agttgtcaca agcccacact ttcttctggg ataagtatga gaaatcaaac
    17161 tggttcttgg agcaagtcat tgcgacttca gaccaagaat tgactagccg caaggttagc
    17221 ttcttactcc aaacacctca acaagatggc ggtcaatggg atatggtcgt ttccctcttt
    17281 gaaaaatacg gtgtcgtgcc taagtcagtt tatcctgagt ctgtttcatc tagcagcagt
    17341 cgtgagctaa atgcgatcct taataaattg cttcgtcaag atgctcaaat cttgcgtgat
    17401 ttgcttgttt ctggtgcaga tcaagcgact gttcaagcta agaaagaaga cctcttgcaa
    17461 gaaatcttta actttcttgc tatgtcatta ggacttccac cacgcaagtt tgactttgct
    17521 tatcgcgata aagataacaa ctataaaagt gaaaaaggaa tcacaccaca agagttttac
    17581 aagaaatatg tcaatcttcc tttagaagac tacgtttctg ttatcaatgc tccaactgct
    17641 gataaacctt acggaaaatc ttacacagtt gagatgttgg ggaatgtggt tggtagccgt
    17701 gcagttcgct acatcaacgt tccaatggag cgcttgaaag aattggcgat tgcccaaatg
    17761 caagcaggtg agactgtttg gtttggttct gatgtcggcc agctcagcaa ccgtaaggct
    17821 ggcatccttg cgacagatgt ttatgacttt gaatcaagca tggacattaa acttactcaa
    17881 gacaaggctg gacgtttgga ctatagcgaa agcttgatga cccacgccat ggtcttgaca
    17941 ggtgttgact tggacgaaaa tggtaaatca accaagtgga aggttgaaaa ctcatgggga
    18001 gacaaggtcg gtacagatgg ttactttgtt gcctcagacg cttggatgga cgaatacaca
    18061 taccaaatcg ttgttcgtaa ggaattgctg acagcagaag aacaagctgc ctatggagca
    18121 gaaccaatcg tacttgcacc atgggatcca atgggagcct tggctgaata aaagcataga
    18181 aaaaaggaat cagattttag aacctggttc ctttttagtt gcttgattac atgatgtgaa
    18241 gaacatgtgc cacaataccc actgcgaaga gggcaaggat aatagtgatt ggagatactt
    18301 ttttcttaag taagtacatg caaagtaaag taaggagtag tcctgataat ccaggaatca
    18361 acatatccaa gttttgttgg aaagtagtaa ctttttcagg agtttgagac aatccttgtc
    18421 ctacttgtgc gaatgcttct tggatacctt tagacccttc tggcaattta tcccaatgga
    18481 tataagcctt ttcatctagt tgaactttag aaacatcgaa agcaaattta atatttaccc
    18541 agcgttgaac aaggacagca agaatgaaca tcccaaggat agaagctcct ttagtgatat
    18601 cttgaaggat accaccagac atatctttag tgatttctga tccagccttg tatccaatct
    18661 cttgaacata ccacaagaat gacatacgaa tcaagttcca tgcaacaaag aagaggagtg
    18721 gccccaagat attgccagta agggcaagtg aagcaccgag agatccaagg attgggcgta
    18781 ctgtaaacca gaatactggg tcaccgatac cagcaagagg tcccatcata ccgattttaa
    18841 ccccttggat agcagcgtca tcgatttcca caccgttagc acgttcttct tcaagcgcaa
    18901 gagtaacccc catgactgga gcagctacgt atggatgagt gttgaagaac tcaaggtgac
    18961 gctcaagagc agcgatttga tcttcttttt tagtatagag ttttttgata gctggaatga
    19021 gtgtataagc ccagcccaag ttttgcatcc gttcaaagtt ccaagaccct tgtaagaagg
    19081 ttgaacgcca ccaaactttt ttacgatctg atttagttaa ttgaagtttt tcagtcatga
    19141 tgttttcagt cctttcttat cttagtagtc ttctaggata tcgccgattg ggtcgttaga
    19201 agttgcggct cctccgccac catttccacc agttttagaa aggtgaaggt agataagagc
    19261 gatagcaaca ccgatagcac cgaatccgat tagagtaata tctgacacag cagcaagaac
    19321 gaaaccaaga gcgaagaatg gccatacttc acgagttgcc atcatgttga taaccatggc
    19381 gtaaccaacg gcaacgacca taccaccacc gatagccata ccatctttga gccagtctgg
    19441 catggcacta aggatacttt gtacagtttc agttggtacc ataaggagaa gagctgcagg
    19501 aagcgcgata cgaagtcctt ggaaaagtag cgcaatgaaa tgagcacgct ccacagcgcc
    19561 gaagtcacct tttttagcgg cagcatcagc agtgtgaacc aatccaactg aaattgtacg
    19621 aacaatcata gttaagaata gaccagctac ggcaagaggg atagcaaccg cttgggcaac
    19681 accgatacca gtcttggtaa agtcaccacc aagaaccatg ataatggcag cagcgacaga
    19741 agcaagtgca gcatcaggag cgatagcagc accgatattt gaccaaccaa gggcaatcat
    19801 ttgaagcgat ccaccgagga taatccctgc ttccaagtga cctgttacaa gcccaataag
    19861 ggtacaggct acaagtggtt ggtgaaattg gaactggtcg aggatgcctt caagacctgc
    19921 aaagaaggct acaacgacta ctaaaaccat agaaataata gacatgttta aaatcctttc
    19981 ataaataatg gcttatttga cattggcttt gttaatcaag tcaaacaaat cttttttaga
    20041 atcatttggt actttacgga catcaaattc aacacccaag tcacgcattt tttcaaatgt
    20101 agcaacatct tctttgtcca tagacaaaac ggtattgacc aatgttttac ctgttgagtg
    20161 agccatagaa ccaacgttaa gagtcttgat tggcacgccg ccttcgatgg cacgaagggc
    20221 atcttgaggt gtttcaaaca agataagggc atgtgtttct ccaaaacgtg ggtcttttga
    20281 aatctcaatc agtttttgaa ttggaaccac gttagccttg acattacctg gagctgcttg
    20341 tttaatcaat tctttacgaa ggtcgtcttt agccacgtta tctgaagcaa cgatgatacg
    20401 atttgctttt gaatctggag tccaagcagt tgcaacctga ccgtgaagta gacgtgtgtc
    20461 aagacgggca agattgattt tcaatttacc gtctccgata acagttcctt ctgggatagc
    20521 agtttgggca actggagcag ctgcagcgct tgcaacttct tcaactggat ttagctcttc
    20581 tggaagagct ttgatgccat ctttggcttc tttaatgata ttagcagcga ctttttctac
    20641 acctgcagca gcgtccatga ggcgctctgt gtaggcttga atcaacatcg gtaagttaag
    20701 tcctgtgatg atggcaaact tacgctcagg attttctccc atcacgcgac tagcttggtt
    20761 aaatggagaa ccactccaaa ggtcagccaa aactagaacc tcatcttctg cgtcaaatgc
    20821 agcaacagcg ttattaaact tagcgtatag atcatcagga ccttcatttg gcataaaggt
    20881 cacaacttga accttttctt gttcaccaaa gatcatagat cctgactgat gaatacccgc
    20941 agcaaattcg ccgtggctcg caataatgat tccgatactc attattgtca ttcctccttt
    21001 tttgttttag ttttcattta agaaaacttt aagactgttt aagtataaac cgttttcata
    21061 aaaaaagcaa ctatttatca taaaaaatta aaaaattttt atttttgtat gttgatatgt
    21121 tgagtttttg aggagtaatc ttgaattctt atttaaaatt taatataaaa aagttggaag
    21181 aagcttccaa cttttaaaat aggtttctat taaattagtg ggtgaagtcg agtaccatac
    21241 gtccttggat ttggcctttt tccatttcgt cgaaaatggc aacagcatct tctactggac
    21301 gtttttgaac aactgggact accagacctt ctgcaccaaa ttggaaggct tcttctaagt
    21361 ctttacgagt tccgacaaga gaaccgatga cttggattcc atcgaggact gttttaacga
    21421 tgctgagttc catcatttca gaaggaagac caacagcgac gacgcgacca ccagcacgaa
    21481 tggagtcaac agcctggttg aaggcaactt tagacacagc agttacgaca gctgaatgag
    21541 ctcctccatc agttttttct ttaatgagtc cagctacatc ttcaacttcg aggccgttaa
    21601 tcacaatgtc agcgcctact tcttttgcaa gggtaagttt gtcattgttg atatcgactg
    21661 cgataacatg agcattgaat acttttttag cgtattgaac agcgaggtta ccaagtccac
    21721 cagcaccgta aagaacaacc cattggcctg gttcaacttt tgcttctttg atagctttat
    21781 aggttgttac tccagcacat gtgatagaag aagcttgggc tggatcaagt ccgtcaggaa
    21841 ctttgacagc atagtcagca gttacgatac attgttcagc cataccaccg tctactgagt
    21901 agccagcatt tttcactgta cggcaaaggg tttcgcgacc agttgtacag tattcgcaag
    21961 tgccacatcc ttcaaagaac caagcaacgc tgacgcggtc accgacttta aggcttttca
    22021 catctggagc aatctcttta acgataccga taccttcgtg cccaagaaca cgtcctggga
    22081 cttgaccaaa gtcaccatga gcaacgtgga ggtcggtgtg gcaaacgcca cagtattcaa
    22141 cttctacaag tgcttcccca gtttcaagtg gacggagtac tttttcttca atagcaacac
    22201 cagtgctttc tggatttaca acaacagctt tcatagctat cctccttgat attgaccgag
    22261 aacagggaca acgggactgg attgattttt tgtcaacaga gtcgagtgtg acgagctctc
    22321 ttgtatttat atgtgaagta tatcacaaaa ggaagccttt tccaaggttt tggagacaaa
    22381 aagtagaaca atcgattaac tggttgatga gactgtgaaa agagcacaaa gaccagcttg
    22441 caagctggtc atactcttcg aaaatctctt caaaccacgt cagcttcatc tacaacctca
    22501 aagcagtgct ttgagcaacc tacggctagc ttcctagttt gctctttgat tctcattgag
    22561 tatcagtata ggttataaga ataagtcttg tagggttttg gcaaccccat cttggtcgtt
    22621 ggtaagggaa atttgctcat ctgcataagg gagtagctct ggattggcat ttttcatggc
    22681 ataacccttc ccagcaaaag cgagcatttc ggtatcattg tgttcatctc caaaggcaat
    22741 caaatctttt ttgtcacgat tcattatctt gagcaagtag tccaaagcaa aggccttgtt
    22801 gacacctttt ggggtacatt caaggatatt gagcggacct ccccaggtat tgatagaaag
    22861 ttgatgctgg tagaaggcgt tcatttcttt tgccaaggca tatttgtcac tggctctggt
    22921 ctgcaagagg atacagttag ggtccttggt caccaattca ggctggaatt gatcttcagg
    22981 ctggaaagct tctacaccaa atagtttggg attggcaatt tcttcattgg gatttgtaat
    23041 gtagaatttt ttacgatatt ctccagcgat aaaatcggct tgaatgtcct ctgaacgttg
    23101 aaccatatct agcagatatt ttttgtctac agtcaaacac ttttcaaaat cccaaacttg
    23161 gtctggtaaa tgagtaaggg atccgttgaa gttaatcata ggagtgtcta agcccagttc
    23221 acggtaaaaa tcttttgaca tacggtaagg gcgacctgtc gtaataataa cctgatggcc
    23281 tttttcagca acttttttga tggttctttt ggtaaagtca gaaatttgac tgtctgagtt
    23341 gagcagggtt ccatccaggt caactgcaat aatttttttc gtcatatgga cctttctagt
    23401 gtgttttcag ataagatgtc ttctattata acagaaagca ggcagaaaag cagattccaa
    23461 acaaaaaatg aaattggatt aatttcttaa acaaatcaaa caaagacatt gaaaaagtga
    23521 atgataaatg atataattct attattgttc gtaaaaatta aaaggagatt gatgatggac
    23581 aaattattta aactaaaaga gaacggtaca gacgttcgta cagaggttct cgctggttta
    23641 acaactttct ttgcaatgag ctatattctc tttgtaaacc cacaaatact ttcacaaaca
    23701 ggaatgcctg ctcagggcgt cttcctagcg acgattattg gtgcagtagc gggtaccttg
    23761 atgatggctt tttatgctaa cttaccttat gcccaagcac caggtatggg actcaatgcc
    23821 ttctttacct ttacagttgt attcgggctt ggttattctt ggcaagaagc cctagctatg
    23881 gtcttcatct gtgggattat ttcattgatt attaccttga caaatgttcg taaaatgatc
    23941 attgaatcga ttcccaatgc tcttcgctca gctatttcag ctggtatcgg tgtcttcctt
    24001 gcctatgtag ggattaagaa tgctggactt ttgaaattca cgattgatcc aggcaactat
    24061 actgttgtag gagaaggggc tgacaaagct caagcaacga ttgcagcaaa ctcttcagca
    24121 gttccaggat tggtcagctt taataatcca gctgttttag tggctcttgc aggacttgcc
    24181 attactatct tctttgtcat caaagggatt aaagggggaa ttattctctc tatcttgaca
    24241 acaactgttc ttgctattgc agttggtttg gttgatttgt ctagtatcga ttttgctaat
    24301 aaccatgttg gtgcagcttt tgaagatttg aagacaatct ttggtgcagc tcttggttca
    24361 gaaggtttgg gagctttggt ttcagataca gctcgcttgc ctgaaactct gatggccatt
    24421 cttgccttct cattgacaga tatttttgac acaattggta ccttgatcgg tacaggtgaa
    24481 aaagttggta ttgtagcgac aaatggtgaa aatcaccaat cagccaaatt ggataaggct
    24541 ctttactctg atttgattgg aacgacagtc ggtgccattg caggtacttc aaacgtaacg
    24601 acttatgttg agtctgctgc tggtatcggt gcaggtggac gtactggttt gacagccttg
    24661 gttgtagcta tctgttttgc gatttcaagc ttctttagcc cacttctagc gatcgtacca
    24721 acagcggcta cagctccaat cttgattatc gttgggatta tgatgcttgg tagcttgaaa
    24781 aatatccatt gggatgatat gtctgaagca gttcctgcct tcttcacatc tatctttatg
    24841 ggattcagct actctatcac tcaagggatt gcagttggtt tcttgactta cactttgact
    24901 aagcttgtca aaggtcaagt taaagatgtt catgccatga tttggatttt ggatgccttg
    24961 tttatcctta actacatcag catggcctta taatagaatg acccaggggg atttcccccc
    25021 ttttttaata caaaggagat aggtgatgaa agagaaaaat atgtggaaag aattgttgaa
    25081 tcgtgcaggc tggattttgg tctttttact tgccgtcctt ttatatcagg ttcccctagt
    25141 ggttacctct attttgactt taaaagaagt agccctgcta cagtcagggc tgatagttac
    25201 tggcctttca attgtggttc tggctctatt tattatggga gctcgtaaaa ccaagttagc
    25261 tagttttaat ttttcttttt ttagagctaa agatttggca cgtttgggct tgagttattt
    25321 agttattgtc gggtcaaata tacttggttc tatcttgttg caactgtcaa atgagacgac
    25381 aacagctaac cagtctcaga ttaacgatat ggttcagaat agttctctga tttctagctt
    25441 cttcttgcta gccttgcttg ctccaatttg tgaggaaatc ttgtgccgtg ggattgttcc
    25501 taaaaagatt ttccgaggca aggagaactt gggatttgta gtcggtacga ttgtgtttgc
    25561 tttattgcat caaccaagta atttaccttc tttattgatt tatggaggta tgtcgacagt
    25621 tctatcttgg acggcctaca agacccaacg tttggaaatg tcgatcttgc ttcacatgat
    25681 tgttaatggg attgctttct gtttgttggc tcttgtggtg attatgagtc ggacattagg
    25741 aatttctgtg taaaagtttt tatgtaggaa ccgacctctt tctactaggg aaagatgaat
    25801 gcaatcgtgt ccatcttttt ctttttatgg taaaatagaa aaataatatg atgaaaatcc
    25861 ttgagggagt gaccgatatg tcaagtaaag ccaatcatgc aaagacagtt atttgcggaa
    25921 ttatcaatgt aaccccagac tccttttcgg acggtggtca attttttgct cttgagcagg
    25981 cactccagca ggctcgtaaa ttgatagcag aaggagccag tatgctcgat atcggcggag
    26041 aatcgactcg gccgggcagt agctatgttg agatagaaga ggaaatccag cgtgttgttc
    26101 cagtgatcaa agcgattcgc aaggaaagtg atgtccttat ttctatcgat acttggaaaa
    26161 gtcaggtggc agaggctgct ttggctgctg gtgccaatct agttaatgat atcactggtc
    26221 tcatgggcga tgaaaaaatg gcccatgtgg ttgctaaagc tggagcgaaa gtagtcatca
    26281 tgtttaatcc agtcatggct cgacctcaac atcctagttc gcttatcttc cctcattttg
    26341 gctttggtca aacctttaca gaaaaagagt tagctgactt tgaaacattg ccaatcgaag
    26401 acttgatggt ggctttcttt gaacgagcac tagcgagagc ggcagaagct ggtattacac
    26461 cagaaaatat cctgttggat ccaggaattg gctttggtct gaccaagaaa gaaaatctcc
    26521 tccttttacg ggacctggat aaactacatc agaagggcta tccaatcttt ctcggagtgt
    26581 cgcgcaagcg atttgtcatc aatatccttg aagaaagtgg gtttgaagtc aatcctgaga
    26641 cagagcttgg tttccgaaat cgggacacgg cttcggctca tgtaactagt atcgctgcga
    26701 gacagggtgt agaagtggtg cgcgtgcatg acgtagctag tcacaggatg gcagttgaaa
    26761 ttgcctctgc cattcgtctg gctgatgaag cggaaaattt agatttaaaa caatataaat
    26821 aagatgaaag aaattgaaaa caatcagtgg attgctaact accggacgga tcaaccgcat
    26881 tttggattgg aacgaatggt ggaactgtta gctttgcgtg gcaatcccca tctcaaactc
    26941 aaggtcctcc atatcggagg gactaacggc aagggctcga ctattgcttt tttgaaaaag
    27001 atgctagaaa agctagggct gagagttggc gtgtttagct cgccctatct cattcattac
    27061 acagaccaga ttagcatcaa tggggaatcg atctcagaag cgaggctaga agctctcatg
    27121 gcagactatc agtctttgct ggagggagaa gcggtcgcca atttacaggg cacaaccgag
    27181 tttgagatta tcacagccct ggcctatgac tactttgcct cagagcaagt agatgtggcc
    27241 atcatggaag ttggcatggg tggacttttg gatagtacca atgtctgtca gcccattttg
    27301 acaggaatta caactattgg cttggatcat gtggccctac ttggtgacac cttggaggcc
    27361 atagcagagc agaaggcagg tattatcaaa caagggatac ccttggtaac agggcgtatt
    27421 gctccagaag ccttgactgt gattgaccgc attgcggaag ggaaagatgc gccgagactt
    27481 gcctacggga cagattatca ggttcgtcat caagaaagtg tggtgacagg ggaagtcttt
    27541 gactatacaa gtgctgtcag acaaggtcgc ttccagacta gcctgcttgg tttgtaccaa
    27601 atagagaatg ctgggatggc catagcttta cttgatactt tttgtcaaga agatggtcga
    27661 gagctagcaa gcaatgactt tcttggtcaa gccttggaag aaacaagttg gccagggcgt
    27721 ttggaaatcg tgtcaagaga tcccttgatg attttggatg gagcccataa tccccatgct
    27781 atcaaggcct tgttggtaac cttgcaagaa cgttttgcgg attatcataa ggaaatcctc
    27841 ttcacttgta tcaaaaccaa agccttggag gatatgttgg acttgctggg agccatgcca
    27901 gataccgagc ttactctaac acattttgcg gatagtcggg cgacggatga aagcgtgctg
    27961 aaagaggcag ctaagtctag aaatctcagc taccaagatt ggcatgattt tctagagcag
    28021 aatttgacag ataaaaaaga agagaaacaa acagttagga ttgtcacagg ttccttgtat
    28081 ttcttgagcc aagtgagggc ctatctgatg gagaggaaga acgagaatgg atacacaaaa
    28141 gattgaagca gctgtaaaaa tgattatcga ggctgtagga gagaacgcta atcgcgaggg
    28201 cttgcaggaa acacctgctc gtgtagcccg tatgtatcaa gagatttttt caggtcttgg
    28261 tcaaacagca gaggaacatt tgtcaaaatc ctttgaaatt attgacgata atatggtggt
    28321 agaaaaggat atctttttcc ataccatgtg tgaacaccac ttcttgccat tttatggtag
    28381 agcgcacatt gcctacattc cagatggtcg tgtggcaggc ttgtctaagc tagcccgtac
    28441 ggttgaagtt tattcgaaaa aaccacaaat tcaagaacgt ttgaatatcg aagtggccga
    28501 tgccttgatg gactatctag gtgctaaagg agcctttgtt gtcattgagg cggaacatat
    28561 gtgtatgagt atgcgtggtg ttagaaaacc aggcactgca accttgacga cagtagctcg
    28621 tggtctattt gaaacagata aggacctccg cgaccaagct tatcgtttaa tggggctata
    28681 aaaagaatcc gcttcaagcg gatttttcta gaaaggaatc attatggatc aactgcagat
    28741 taaggatttg gaaatgtttg cctatcatgg tctttttcct agtgagaaag aattggggca
    28801 gaaatttgtc gtttcagcca tcctatccta tgatatgacc aaggcagcta cagacttgga
    28861 tttaacagcc tctgtccatt acggagaatt atgtcagcag tggacgactt ggtttcagga
    28921 aacgagtgaa gatttgattg aaacggtagc ctataaactg gtggaacgta cctttgagtt
    28981 ttatcctctt gtccaagaaa tgaagttgga actgaaaaaa ccttgggcac cggtgcattt
    29041 gtcactagat acttgctcgg taaccattca tcgccgcaag caacgagcct ttatcgccct
    29101 aggaagcaat atgggagata aacaagcaaa cttgaagcaa gccattgaca aactgcgagc
    29161 tcgtggcatc tatattctca aagagtccag tgtcttagcg acggagcctt ggggtggagt
    29221 ggagcaggat agctttgcca atcaagtggt tgaggtggaa acctggctac cagcacaaga
    29281 cttgttagaa accttgttag ccattgagtc agagctggga cgggtgagag aagtgcattg
    29341 gggacctcgt ttgattgatt tggacttgct ctttgtggag gaccagatcc tttatacaga
    29401 cgacctcata ttgcctcatc cttacatagc ggaacgcctt tttgtccttg agtccttaca
    29461 ggaaattgcg cctcatttta tccatccgac attaaaacaa ccgatccgca acttgtatga
    29521 tgctttgaaa aaatagaaaa actctagttt tcagttactt gcaactgaag gctagagttt
    29581 ttaaaatagg tcattttctt ctgggaggag gatagtttct ctaccgtaca tgtctaaaac
    29641 cagtactctt gggggataac gagggtcgaa aggatggtta aagtcaaaat caatggctgt
    29701 agggaggtgt tgacttgaaa agtggaaggt aatctttcct tggttattaa gcaattgaaa
    29761 ctcgagttct tcttccaatt caaagacatt ttttaagaaa tgatcgatga tataccaaaa
    29821 agagtcaatg atgtcatcgg gcaagctggt aacaatgcca aaactagcag accgcatgtg
    29881 ggtattggta aaagccatat ctctgtcccc tttcttttcc cttatcatac agcaaatagg
    29941 attaaaaatc aagaaaaggt gattttttga aaaggatttt aactacaggg aaaaataagg
    30001 aaaaaaattc ccaaaaatct accgaagtta ataggtaaat tcccaaatta acttgattat
    30061 ataactttca gtta
//
LOCUS       DAVBIC010000026        29756 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.026, whole genome shotgun sequence.
ACCESSION   DAVBIC010000026 DAVBIC010000000
VERSION     DAVBIC010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29756)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29756)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29756
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.026"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            132..494
                     /locus_tag="VQ664_001116"
     CDS             132..494
                     /locus_tag="VQ664_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789286.1"
                     /translation="MRLASESRQILDKLKDDVYNKLGYEVSYSSIVSQAVREYVPKKE
                     RIDWIKLKETAIPFSSLKQSNNWEYQTSLMLEKDVLILLSELQNFFLDVFQAKRIHRA
                     FCIRLCLRAQFLLSNNDS"
     gene            902..1201
                     /locus_tag="VQ664_001117"
     CDS             902..1201
                     /locus_tag="VQ664_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789287.1"
                     /translation="MNRNVLNFLRTESAERVSLYIDKANRLEGDVTLLAPSSQDLEDI
                     KNAMFSNPNLELKVARLDVMKKIAYASTRNHYLTGATIFGDISKGTYNCDPKSYV"
     gene            complement(1296..1733)
                     /locus_tag="VQ664_001118"
     CDS             complement(1296..1733)
                     /locus_tag="VQ664_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789288.1"
                     /translation="MKKLYRIHFIAIAVIDLLLFAFFITRLETSFEWLLLSGLIFFLA
                     QGLLLFLLVVRLKHQFAEIYPQINKKIRFYYLGVLTIDFLFFVLLAFISSQRFSSLMP
                     IITACHSTFYYMTADYLRENYPDFYDKHISNTYTILSISSFLV"
     gene            complement(1864..2498)
                     /locus_tag="VQ664_001119"
                     /pseudo
     CDS             complement(1864..2498)
                     /locus_tag="VQ664_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819460.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
     gene            complement(2708..3358)
                     /locus_tag="VQ664_001120"
     CDS             complement(2708..3358)
                     /locus_tag="VQ664_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HET2789289.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRMHD
                     SFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNMDIAKQLYVEKIN"
     gene            3470..4312
                     /locus_tag="VQ664_001121"
     CDS             3470..4312
                     /locus_tag="VQ664_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HET2789290.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADARQLGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQEEFDRLVTHPPCDIAVY
                     GHIHQQLLRYGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDDKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            4388..4825
                     /locus_tag="VQ664_001122"
     CDS             4388..4825
                     /locus_tag="VQ664_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HET2789291.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKKSKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTDIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            4893..5195
                     /locus_tag="VQ664_001123"
     CDS             4893..5195
                     /locus_tag="VQ664_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789292.1"
                     /translation="MYLVIGIVLAFIVSFWKDNRSLWNPVLFLLSLISSYFYLSYLFY
                     KNGYENVQLAFYVFAFVLLPFLLFLSGIFLIYNGVILLKREGRSKPHYLSMLFDFY"
     gene            complement(5286..6359)
                     /locus_tag="VQ664_001124"
     CDS             complement(5286..6359)
                     /locus_tag="VQ664_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HET2789293.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPREPTMLTSKNRLQLLDKLAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHKIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSQQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILEAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     ERETLGRLTQLLIDTRYQAWKNR"
     gene            6515..7192
                     /locus_tag="VQ664_001125"
     CDS             6515..7192
                     /locus_tag="VQ664_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2789294.1"
                     /translation="MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            7185..8159
                     /locus_tag="VQ664_001126"
     CDS             7185..8159
                     /locus_tag="VQ664_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HET2789295.1"
                     /translation="MLDWKQFFLAYLRSRSRLFIYLLSLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVEMQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLLLKQVQIEDLVKEIIRKYALFFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(8208..10151)
                     /gene="thrS"
                     /locus_tag="VQ664_001127"
     CDS             complement(8208..10151)
                     /gene="thrS"
                     /locus_tag="VQ664_001127"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HET2789296.1"
                     /translation="MINITFPDGAIREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHGDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVDYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(10209..10385)
                     /locus_tag="VQ664_001128"
                     /pseudo
     CDS             complement(10209..10385)
                     /locus_tag="VQ664_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166032.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
     gene            complement(10392..10532)
                     /locus_tag="VQ664_001129"
     CDS             complement(10392..10532)
                     /locus_tag="VQ664_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HET2789297.1"
                     /translation="MELQELVERSWAIRQAYHELEVKHHDFKWTVEEDLLALSNDIGN
                     FQ"
     gene            complement(10963..11163)
                     /locus_tag="VQ664_001130"
     CDS             complement(10963..11163)
                     /locus_tag="VQ664_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001826938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789298.1"
                     /translation="MRRFYSHLPYYLVILFFYWPLYELFLLVVSDPLTLKGLYINNLL
                     FFTPMVILIVSLLYSYRFRFSL"
     gene            11402..11947
                     /locus_tag="VQ664_001131"
     CDS             11402..11947
                     /locus_tag="VQ664_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001852743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HET2789299.1"
                     /translation="MKLAVIAANGQAGKAIVEEAVKRGHEVTAIVRSENKSQAESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVVGGSGS
                     LYIDETKTTRLLDTPDFPEEFKSLAKAQADELDLLRTKNNLNWAFVSPAVDFIPDGEK
                     TGNYILAGEIFTTNEKRNKPD"
     gene            12173..12442
                     /gene="rpsO"
                     /locus_tag="VQ664_001132"
     CDS             12173..12442
                     /gene="rpsO"
                     /locus_tag="VQ664_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HET2789300.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            13257..13871
                     /locus_tag="VQ664_001133"
     CDS             13257..13871
                     /locus_tag="VQ664_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HET2789301.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAIVGEDAEEEEEEIIERL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(14163..14912)
                     /locus_tag="VQ664_001134"
     CDS             complement(14163..14912)
                     /locus_tag="VQ664_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HET2789302.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            15045..17381
                     /locus_tag="VQ664_001135"
     CDS             15045..17381
                     /locus_tag="VQ664_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HET2789303.1"
                     /translation="MDKNKIMGLTQREIKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNFAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAVASILTSYMA
                     HSEDKNPTAQAIRQRFQGQVVYPMLSNLPFSSDRKWGAMELEGLGIVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDPIREGAAETLNY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHSYVDCSKITDEELIALAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEPNFLRKSMLRALPSALMVVFSVLFVKIF
                     GTSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEISTLTEQTLPVYGVMMLVFTVIFILTSRYQARK"
     gene            17483..18160
                     /locus_tag="VQ664_001136"
     CDS             17483..18160
                     /locus_tag="VQ664_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HET2789304.1"
                     /translation="MISKRLELVASFVSQGAILLDVGSDHAYLPIELVERGQIKSAIA
                     GEVVEGPYQSAVKNVEAHGLKEKIQVRLANGLAAFEETDQVSVITIAGMGGRLIARIL
                     EEGLGKLANVERLILQPNNREDDLRIWLQDHGFQIVAESILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLSKEVSPVFVQKWQKEAEKLEFALGQIPEKNLEERQVLVDKIQAIK
                     EVLHVSK"
     gene            18147..18944
                     /locus_tag="VQ664_001137"
     CDS             18147..18944
                     /locus_tag="VQ664_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HET2789305.1"
                     /translation="MLASEVIHAYEAFCPQEFSMEGDSRGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLGIEETTYLQETGPERGIGRIGNIQPQTFWELAQQVKQVFDLDS
                     LRMVHYQENDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIAALLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            18961..20064
                     /locus_tag="VQ664_001138"
     CDS             18961..20064
                     /locus_tag="VQ664_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HET2789306.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQKIDFYQRSGVFLLKKDESKLE
                     ELYQLALQRREESPLIGQLAILDQASANELFPGLQGFDRLLYASGGARVDGQLLVTRL
                     LEASHVKLVKEKVTLTPLASGYQIGEEEFEQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLVQDMEAYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDETLLQQME
                     EATLTHYLILAEATSKSERVGIRAYTSDFSPFFGQVPDLTGVYAASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPENYPIENYVKRVKSE"
     gene            20071..20262
                     /locus_tag="VQ664_001139"
     CDS             20071..20262
                     /locus_tag="VQ664_001139"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789307.1"
                     /translation="MKIKEQTRKLAAGYSKHCFEVVDRTDEVSSKHCFEVVDRTDEVS
                     NHTHGKATLTWFELDFRRV"
     gene            20365..21384
                     /gene="galE"
                     /locus_tag="VQ664_001140"
     CDS             20365..21384
                     /gene="galE"
                     /locus_tag="VQ664_001140"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HET2789308.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTATLRDIFKQEEPTGVIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAIEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            21386..22339
                     /locus_tag="VQ664_001141"
     CDS             21386..22339
                     /locus_tag="VQ664_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET2789309.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTYYLDYPNVERQAGKTSWSFRKLFFYSIE
                     GIINFSDFPLIIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSDDRLKKIEFI"
     gene            22491..23156
                     /locus_tag="VQ664_001142"
     CDS             22491..23156
                     /locus_tag="VQ664_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000949235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789310.1"
                     /translation="MLSKEDYTEEIGLIKKQNYVEAELYPIVADIIKPTLKDSLSKRY
                     VFGRQRRGLGQIYYGLSNFPDIVILDKTYENKSRKSIKIEEWKKLRGCVEVKNLNYSL
                     ITEEKIKSTISNSFEHITGEMEQLTGEMGQLIGDLLWYKKVIYTNGIEWRFLSLDDKE
                     EIDNTIVEVVNKRIETEEAGNSFDWWKNIKDLSFNYTDICLSKDCRQEWNEFVKRVKE
                     IEW"
     gene            23195..23296
                     /locus_tag="VQ664_001143"
                     /pseudo
     CDS             23195..23296
                     /locus_tag="VQ664_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677122.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group 2 glycosyl transferase"
     gene            complement(23347..23553)
                     /locus_tag="VQ664_001144"
     CDS             complement(23347..23553)
                     /locus_tag="VQ664_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HET2789311.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDVLEAVKNCPTRALIGNQEA"
     gene            23605..24081
                     /locus_tag="VQ664_001145"
     CDS             23605..24081
                     /locus_tag="VQ664_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM domain-containing protein"
                     /protein_id="HET2789312.1"
                     /translation="MAKEPWQEDIYDQEESRAERRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSQPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            24090..24761
                     /locus_tag="VQ664_001146"
     CDS             24090..24761
                     /locus_tag="VQ664_001146"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HET2789313.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDFETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            24892..25230
                     /locus_tag="VQ664_001147"
     CDS             24892..25230
                     /locus_tag="VQ664_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HET2789314.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLADGDTVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            25233..25862
                     /locus_tag="VQ664_001148"
     CDS             25233..25862
                     /locus_tag="VQ664_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HET2789315.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITKHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            26102..27253
                     /locus_tag="VQ664_001149"
     CDS             26102..27253
                     /locus_tag="VQ664_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET2789316.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVLPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            27566..28315
                     /gene="truA"
                     /locus_tag="VQ664_001150"
     CDS             27566..28315
                     /gene="truA"
                     /locus_tag="VQ664_001150"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HET2789317.1"
                     /translation="MTRYKATISYDGYAFAGFQRQPHARSVQEEIEKTLTRLNKGQAI
                     TVHGAGRTDSGVHALGQVIHFDLPYQMDEEKLRFALDTQSPEDIDVISIELVADDFHC
                     RYAKHSKTYEFTVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IDLILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            28305..29078
                     /locus_tag="VQ664_001151"
     CDS             28305..29078
                     /locus_tag="VQ664_001151"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HET2789318.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LIKGDKLLPAVESSKAFVYRAIAQADQYGVRQYEANKNN"
     gene            29056..29517
                     /locus_tag="VQ664_001152"
     CDS             29056..29517
                     /locus_tag="VQ664_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET2789319.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLIDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     ATIAMVGGYALGSTLMNGWAAALPEILPNFMQNMVGMIVGFILSQSIKKIK"
BASE COUNT         8718 a         5367 c         6692 g         8979 t
ORIGIN      
        1 taaattttta gattgtggaa tttttttcaa cttaattctt gatttttttt ctaaattgtt
       61 atatacttaa tttacgggat aacagaatcc cgtcagaaag gggtgataat atgggaaaag
      121 agaatgttag aatgcgttta gcgtctgaat ccagacagat attagataag cttaaagatg
      181 atgtttacaa taaattaggc tatgaagtaa gctattccag tattgttagt caagctgtta
      241 gagaatacgt tcctaaaaaa gaacgtatag attggataaa attaaaagag acagctatac
      301 ctttttcatc gttaaaacag agcaataatt gggagtacca gacatcactt atgttagaga
      361 aagatgtatt aatcttactg tctgaactac aaaatttttt cttagatgtc ttccaagcga
      421 aacgtataca tagggcattt tgtatacgtc tatgtttgag agcgcaattt ttattaagta
      481 ataatgattc ttaatactat caatattaat gcggagtgta atgctccgca aaaataaaac
      541 ctattacggg ataaaaacac tactttattt aggatggaaa taagaacgta ttttttacta
      601 atattgttta gaaaggagtt tctttatgac accagaagaa caaactgctt tggaatactt
      661 ttatgaggaa ctcgagagtt acggtgaaga tgagcaagga gaggtctttg atttgtatga
      721 taattaaatc atctccatag tttctgagaa taattgagaa actatactct aaatcatagg
      781 tttatgtaaa gctagatata cacaaaagga ggtacgaatg aagatgaaag ctagagcttc
      841 accgttgaat tgattttgtt tctagaaaaa atcaataatt agaaaaatac gaggtaaaaa
      901 aatgaataga aatgtactaa attttctgcg aacagaaagt gctgaaagag ttagtcttta
      961 tatagacaag gctaatagat tggagggcga tgtaactcta ctcgcaccta gttctcaaga
     1021 tttggaagat attaaaaatg ctatgttttc caatcctaat ctcgagctaa aagtagcgag
     1081 actggatgtg atgaagaaaa tagcatatgc ttctacaaga aatcattatt taacaggggc
     1141 tacgattttt ggggatattt cgaaaggaac atacaattgt gatcctaaaa gttatgtcta
     1201 atataaggga ggttaatccc tccccttgtt tttgaaaatc gaaaggaaaa gtataaaaat
     1261 gaaagttaat gaatatttct ggagaacgag ctgtcttata ctaaaaaaga agaaatcgat
     1321 aaaatagtat acgtgttaga gatgtgtttg tcgtaaaagt ctggatagtt ttctcttagg
     1381 tagtcagctg tcatataata aaaagtagaa tggcaagcag tgatgattgg cataagagat
     1441 gaaaaacgct gagaactaat gaaggctaag agaacaaaaa atagaaaatc aatggtgaga
     1501 acccctaaat agtagaagcg aatcttttta ttgatttgag gataaatctc agcgaattga
     1561 tgtttgagtc ggacgaccaa gagaaatagc aggagtcctt gagcaaggaa gaaaattaaa
     1621 ccagagagca agagccactc aaaagatgtc tcgagtctag tgataaaaaa tgcaaatagt
     1681 agcaaatcaa taactgcaat tgctataaaa tggattctat agagtttttt catgacaaga
     1741 cctccctctt ttatctaact tcattctact ctaaaagaat gggagttaca actaaaatga
     1801 taaaaatagc agaggggaga ttctcttaag ttggctagta ttctttattt gagtttcctt
     1861 ctattatcta acttcttcat cattccagac aaataaagct ccgattgcat tgaggatata
     1921 aaagatgtat ttaccgatat tggcgaagtt tccttgaata ccagcttttg tcagctgaac
     1981 gaaattgtaa atcaaccaaa agccccactg tccctcattg ccaatgcatt caaagcattg
     2041 gcaatgaggg acagtgcaaa ggcaatagtt gttacgtagg caaggagatt catcttgccc
     2101 ccatatccga tatagttggt cacaaaggca aagaggaagg cgatgatgga aatgatgatg
     2161 gccgccaatt ttacctgttt ttggctcatt tggttgggtc tgccttcttg cgaagctttc
     2221 catttcttta tagcaaaggt ataaatgagg aaggtgacgg gataggtaat gatggccgcc
     2281 ttatttccaa ggatataatc aatagcaccg gacaaaatgg tattaacaat accaaagtaa
     2341 ttttcccatt tgcttaattt ccccgtgaaa cgagtggaca acatggaaat cccaacgttg
     2401 gttacggaaa tcaatccaaa gggtacaaga gctgtccatg gtccccagtc tacaaattta
     2461 tcgaggcgtg agttgaggta accagatgca atcgcaatcc aacgaccaaa gcaaccccga
     2521 agaggtcaaa ctatttagat gtagcaaaaa tttttagtga ttttttcata ggttaaacta
     2581 cctttctttt tttcaaatat tctcccattt tttttcaaat attctaccac caaatgaaag
     2641 taaaataaaa tgatagaaat aaaaccctga aaataaaact ttcagggttg gtaggggact
     2701 tgagaaatta gttgattttc tcgacataga gttgttttgc aatgtccata ttcacttgta
     2761 aatcctcgtc gttactgagg atagtgaagg tattgctgaa gccatcaaac tgcttaactt
     2821 ggagctggtc accgatgtga agtgagtgct tgtccagata atggagaatg tcaaaactat
     2881 cgtgcatccg agtcaggcgg taggcgccag cttccttgat atcagctagt gggaggttat
     2941 tgatttcaac gaggagttct cccttggcag gaatagttcc tccgtggggg caggttttag
     3001 ggaaacctag cagtttatct agtctttcca cgaacaggtc agagacagtg tgttccaaga
     3061 cctcagcttc ctcgtgaatc tggtcacttg tatagtctaa atgatgaact agaaaaactt
     3121 caatcaagcg gtgcttacga tagagctcag agaccagttt gagaccgagg tcagtcagta
     3181 gatagccaca ttccttgtcc tttaggatga gattttcact tttcattcgt ttgatcattt
     3241 cagttacggc agggggagag acttgcatgc gagccgcaat ttccttgttg gtaatcttat
     3301 gcaggtctat gccaatttca taaatacatt ttagatagtc ttctttgttt ggggtcattc
     3361 gtttcctctt gtctaatatc tttatctagt atatcaaaaa aagctagatt tctctagctg
     3421 tgacttttta tgttatactt attgcaagag aaaaaacgag gagatggata tgacgaaaat
     3481 agctcttctt tcagatattc atggaaatac caccgccttg gaggctgttt tggcagatgc
     3541 tcggcagcta ggagtggatg aatactggct tttgggagat attctcatgc cagggacagg
     3601 gcgtagaagg attttggact tgttggatca actaccgatt acggctagag ttttgggaaa
     3661 ctgggaagac agtctttggc atggtgtccg taaggaattg gatagtactc gccctagtca
     3721 acgctatctc ttgcgccagt gccagtatgt tttagaggaa atttccctag aagaaattga
     3781 agtgctccac aatcaacctc ttcaaattca tcgtcagttt ggggatttga cagtgggaat
     3841 tagccatcat ctgcctgata agaactgggg gcgagagttg attcatactg gcaaacaaga
     3901 ggaatttgac cgcttggtga ctcatcctcc ctgtgatatt gctgtttatg gacacattca
     3961 ccagcagttg cttcgttacg ggactggtgg gcaattgatt gtcaatccgg gttcgattgg
     4021 ccaacctttc tttttggacg ctcagctacg gaaggacttg cgggcccagt atatgatttt
     4081 ggagtttgat gacaagggcc tggtagatat ggacttccga cgggtagatt acgatgtggc
     4141 agctgaattg cagctggcta aagacctgag acttccctat tttgaggttt actatgaaag
     4201 tctggtcaat gggatccacc atactcatca tcaggaattt ttgagagaat tggctcagaa
     4261 agagggttgc gatcgggagt tagacgactg gttgaaaagt ggtaacgatt gacattacaa
     4321 ctaaaaaggg tataataata gaaaaagaag agtagaggca gggtagcctc gtaaaaagga
     4381 gaagaggatg caaattccaa gtagatttac cattgcgact catatgctga taatcattgc
     4441 cctcgagggg aagaaaagca aggtgaccag tgattttctg gctgctagtg tcggggtcaa
     4501 tcctgtcatt atcagaaaga tcttgtccca gttgaagaag gcagagctga tttcagtagc
     4561 gcgtggaacg ggcggaacag atattgtcaa ggaccttaag gatattagtc ttttagatgt
     4621 ttatcaggcg gtcgaatgtc ttggtaagac aggtcaactc ttcagtttcc atgacaatcc
     4681 gaatccaaat tgccctgtag gagctcatat tcatgatgtt ttggatcaaa aattggagag
     4741 aattcagttg actatggagg cagaacttgg tcaaaccagt ctagaaaaag tcgtggccga
     4801 tgcagagagt cagatgaagg attaagaggg ataaatgccc tcttttttct ttggataatt
     4861 atgataaaat gtagctatta aaggagtaag aaatgtatct cgttatagga attgtattag
     4921 cctttatagt gtcattttgg aaggataata gaagtttgtg gaatccagta ttatttttat
     4981 tatccctcat ttcaagttat ttttatctat cctacctttt ttataaaaat ggatacgaga
     5041 atgttcagtt agctttttat gtatttgcct ttgtcttact tccttttttg ctttttctaa
     5101 gtggcatctt tttaatctat aatggggtca ttttgttgaa gcgagaggga cgttccaagc
     5161 cccattatct ctcaatgctc tttgattttt attgactatt agattctatt taaaaagact
     5221 tagaatgcac atgaaagtat gtattctagg tcttttgttt tgtatacatt taattttcaa
     5281 gagtattatc tatttttcca tgcctggtaa cgagtatcaa tcaataactg ggtaaggcga
     5341 cccaaggttt ctctttcttc tggagtgagg gattgagctt ggacaaagag atgatgaatg
     5401 tattcaagcg cctttaagga agccaagtca ttgatagagc taataccagc ctcaagaata
     5461 gtgccaaaga agaggtcgaa gtagagctga agttcttcgt cagggactgt ggccacccat
     5521 tctttaaagg ttgtgtctac ttgctggcta tcactgttgg tcttatccag ttggacgaag
     5581 tgcttgtcct caatctgcca actaaaggta tcgtgctggg cgatgccacc cagggcagta
     5641 ctctgaacga tgattttgtg agcaggaatt tccagcatca taccgataat ggaaccttgt
     5701 ggaatgaata tcttgcttct atccattatc ctttgataac ccgcagtctg tgtcaattct
     5761 tgatggagac caggtgcatc aaatgtataa actgctgtga tctgattttg caaactttgc
     5821 tcaatttggc tagcagcata gatagcgaga tttcctccct tggaatgccc agctagaata
     5881 accttttgct taggatgatg ggcaaaaaag ttctttaaat agcgaagggc gtgcttttga
     5941 gcaggaattt ccttcatata ggtcaggtgg aaatcttcct tccagccaat gatactgtca
     6001 tctgtcccac gaaagacaat cagataggta tcgaggctga cacgataagt catagccgca
     6061 aattgctttt gcagttcagg gtcgatgtcg ttgataaaat gggagagttt gcaatttttg
     6121 aagcgcttgt gttgagccaa tttatctaat aattgaaggc gatttttgct agtaagcatg
     6181 gtgggctctc ttggaacctg aggtgctaga tctaaaagac gttgaggaag tgtggagacc
     6241 agattatcaa aggagaggta ggtgatttct attaaggtta gaatgtctaa ctcattcaag
     6301 ggaaggtcgt aataagaatc atatgcgaca tctttcagat agtcaaaaat attggccata
     6361 agagctcctt tctttttatt tatcttagca aatttccctc aaattagcta gtagcatagc
     6421 ctgtttgcac tggctaaaaa caggctattt caaattcagt ttcagaccat ctagcatgga
     6481 aaaatctgtt ataataatgg aaaaggagaa gcgcatgcac aagattttat taatagaaga
     6541 tgatcaggtc attcgtcaac agattgggaa aatgctctct gaatggggat ttgaagtggt
     6601 cctggtagaa gactttatgg aagttttgag tctatttgtt cagtcggaac ctcatctggt
     6661 cctcatggat attggtttgc ccttgtttaa tggttatcac tggtgtcagg aaatccgcaa
     6721 gatttccaag gtacctatca tgtttctttc ttcgagagac caggctatgg atattgtcat
     6781 ggcaatcaat atgggggcgg atgactttgt gaccaagcct tttgaccagc aggttctttt
     6841 agctaaggtt cagggcttgt tgcgtcgttc ctatgagttt gggcgtgatg agagtttgct
     6901 ggaatatgct ggtgttatcc tcaataccaa atccatggat ttacattatc aagggcaagt
     6961 cttgaatttg accaagaatg aattccagat tttacgcgtg ttatttgagc atgcaggcaa
     7021 catcgtagca cgtgacgacc tgatgcggga actttggaac agtgactttt tcattgatga
     7081 taataccctc tctgtcaatg tggctcgttt gcgtaaaaag ttggaggagc agggattggt
     7141 aggatttatc gagaccaaga aaggaatagg gtacggattg aagcatgctt gattggaaac
     7201 aattttttct agcctatctg cgctcccgta gtcgtctttt tatctatctg ctttctttgg
     7261 catttcttgt cttactcttt cagtttttat ttgccagtct aggaatttac ttcctctact
     7321 ttttcttctt gtgttgcttt gtaaccatct tatttttcac ttgggacata ttggtggaaa
     7381 tgcaggtcta tcgccaggaa cttctctatg gagagaggga agccaagtct cctttggaaa
     7441 tagctttagc agaaaaatta gaagcgcgtg agatggaact ctatcagcag aggtcaaaag
     7501 cagaaagaaa actgacggat ttgctggatt actatacctt gtgggtccat cagataaaga
     7561 cccccattgc agccagtcaa ctcttagttg cagaagtggt cgaccgccaa ctgaagcagc
     7621 agctagaaca ggaaattttc aaaatcgact cttataccaa cctagtttta cagtacctgc
     7681 gtttagaaag tttccatgat gatttgctct taaagcaggt tcaaattgag gacttggtca
     7741 aggaaataat tcgtaaatat gctcttttct ttattcaaaa aggcttaaat gtcaatctac
     7801 atgaccttga taaagaaatc gtgacggata aaaagtggct gctagtggtt attgagcaaa
     7861 tcatctcaaa cagtctcaag tacaccaagg aaggtggtct ggagatttat atggatgacc
     7921 aagagctttg tatcaaagat acgggaatcg ggataaaaaa cagtgatgtc ctccgagtat
     7981 ttgaacgtgg cttttcagga tacaatggcc gtttgaccca gcagtcctct ggacttggcc
     8041 tttatctatc taagaaaatt tctgaagaac tggggcacca gattcgtatc gagtctgagg
     8101 tcggaaaagg aacgacagtg cggattcagt ttgctcaagt gaacttagtc cttgagtaaa
     8161 aatagatgag aaaaagcctc cagattggag gcttttatgc tagactctta tttctcaacg
     8221 cgtgatttgt tggcgatatc agctaggata gcttgaacaa aattatcaac tgagacagtt
     8281 tgtgtttctt tttggccgta gcgacgaacg ttgactgttt cgtcttccat ttctttgtct
     8341 ccaacaatta attggtaagg aatcttgctg gtttgtgaag cacggatctt gaactgcatt
     8401 ttttcattgc gctcatctac gtctgcacgg acaccgcggt cacggagttt cttggctact
     8461 tcccaagcgt agtccacgtg tttttcgtta gatactggga tgagggttac ttggtgtggt
     8521 gccagccatg ttgggaaggc ccccttgtag ttctcaatca agatagctgt gaagcgttcc
     8581 atagttgaga taaccccacg gtggatcatg actggacggt gatcttcgcc atcagctccg
     8641 atgtatttga ggtcgaagcg ttctggcaac aagaaatcaa gttggatagt agaaagggtt
     8701 tcttcttttc caagggcagt tttaatctgg atatccaatt ttggtccgta gaaggctgct
     8761 tcaccttcgg cttcaaagta gtccacgccc atttcatcaa gagctgcacg aagcatggtt
     8821 tgggcatttt cccacatctc atcgttatca aagtacttat gagtatcttg agggtcacga
     8881 agagagaggc ggaagcggta gtcagtcaag ttgaagtctt cataaacatc gataatcaac
     8941 tgaagggcac gttggaattc ttcttggatt tgttctggag taacgaatag gtgaccgtcg
     9001 ttgagtgaca tttcacgtac acgttgaagg ccagtgaggg caccagattt ttcgtaacgg
     9061 tgcatcatac cgatttcagc gatacggatt ggcaattcac ggtaagagtg aacatggtgt
     9121 ttgaaaactt ggatgtggtg cggacagttc attggacgaa ggacaaattc ttccccgtca
     9181 cccatgtcca tggttgggaa catgtcttct tggtaatgat cccagtgacc agaagtcttg
     9241 taaagctcaa cagaagcaag tggtggagtg tagacgtgtt ggtagccaga agccaactct
     9301 ttgtttacga tgtagcgttc caattcacga cggatagtcg caccatttgg caaccagaat
     9361 ggcaaacctt gtcccacttc ttgtgaaatc ataaagaggt caagctcttt accaagttta
     9421 cggtggtcac gttccttagc ttcttcacgc atttgaaggt agtttttcaa gtctttcttg
     9481 tcaaaccaag ctgtaccgta gatacgttgc atcatagcgt tgtcgctgtt tccacgccag
     9541 tacgcaccag ctacatggag aaggtggaag atttggatac gacctgttga tggaacgtga
     9601 ggtccacggc agaggtctac atattcaccc tgacgataga tagtcaaacc gccttcgtct
     9661 tctgagtgtt cttcaatcaa ttccaacttg taagggtcat ttttgaagat ttcacgtgcc
     9721 tcgtctttag tcacttcttc acgaatagat gggaagtttt ctttgacgat tttttgcatt
     9781 tcttcttcga tacgaggaag gtcttcgtta gagatttgac cagctgtgtt gtcagtatcg
     9841 tagtagaaac catcttcgat ggctggacca actcccaagt gaatgtctgg gaaaagacga
     9901 cgagctgctt gggcgaacaa gtgagctgct gagtgacgca agattggaag ggcatctccg
     9961 tgatcaggtg tcacaatttc gatgcttcca tcttcagtga tagcgcgagt agtgtcgatg
    10021 agtttgccgt tgaatttacc agccaaggct tttttagcta gggaattgct gatagattgg
    10081 gcaatttcaa aagttgttac gccagattcg aattcacgaa tagcgccatc tgggaaagta
    10141 atgttaatca tgatgttctc cttttttatt atttcatagt ttctaagcat tgatttttta
    10201 tcagcagact acttccaagt tctaacgttc aattgctttt ctttatcaga gaggaagttt
    10261 tccatttccg tcagaatatc tatatccaaa cgttgagaaa gttctaatag tcaccagata
    10321 ttttctgaaa gtttttgttc cagtgtgtag ggtgtttcat catagtagcg tccttgcttt
    10381 gtcatcacca gtcattggaa atttccaata tcattagata aagccaagag gtcttcttct
    10441 accgtccact tgaaatcatg atgcttaact tccagttcgt gataagcttg tcggattgcc
    10501 caactgcgct ccactaattc ttgcaactcc ataattagta tcctaataaa aaaatgcgac
    10561 atcctcgaaa ggacgtcgca acgtggttcc accttcattt atgtacctca aaagagaggg
    10621 acacctctga tcggctctaa cgtggccacc gttttatgtt ttcataaaaa actcaagagt
    10681 agtatcagtt tagacttcct atgcgtttcc agcaaccacg cactctctag tagaaaggga
    10741 ctaagtgact tgtctctatg gattattata gcatgattgt gagatttttc aaggattttg
    10801 tgaaagtttt ttgtttttca ttttttgtag aatatgcttg atgctaatac cagaatccat
    10861 gcccaccaga gcaactgttt catagattag caagtaaatt agtataaaca caccaaaggt
    10921 tatgatagta aagtaaaaga gcagtccgtt accaactaac catcaaagtg agaaacggaa
    10981 acggtagcta tagagtaacg atacaatcaa gattaccata ggtgtaaaga agagaagatt
    11041 gtttatatag agtcccttga gtgtaagggg gtcagaaaca actagcaaga acaactcata
    11101 aagtggccaa taaaagaata atatgaccag atagtagggg agatgggaat agaatctacg
    11161 catgataatc acctcgtttt aaaaaaacag acaacttaga tctcttgcta tgattattat
    11221 agtatgttta aaacaagaaa gtaaatttgt tgacaaagaa gatttttctt ttcactagaa
    11281 tcatggttag ttttcttggt agaaatattt tgataataat taagcaagac tattgacatt
    11341 gattattaag agtgtcacaa ttgttgtaac taaaataatt acaacaagag gggtataaaa
    11401 aatgaaacta gcagttattg cagcaaatgg acaagcgggg aaggcaattg ttgaagaagc
    11461 agtcaaacga ggacatgaag taacggctat tgttcgttct gaaaacaaaa gtcaagctga
    11521 gtctattatt aaaaaagatt tatttgagtt gacaaaagat gatcttactg gatttgatgc
    11581 tgttatttca gcgtttggtg cttatacacc agatacgcta ccgctccaca gcaaatcaat
    11641 cgaactattt aatcagcttc ttgctggaac acagacacgt tttctagttg tagggggatc
    11701 aggaagcctt tatatagatg aaacaaaaac gacacgactt ttagatacgc ctgattttcc
    11761 tgaagaattt aagtcactag caaaagctca agcggatgaa ttggatcttc ttcgtacaaa
    11821 aaataatctc aactgggctt ttgtcagtcc tgctgtagat tttattcccg atggtgaaaa
    11881 aacaggaaac tacattctag caggagaaat ttttactact aatgaaaaaa ggaataagcc
    11941 agattagtta tgcagattat gctattggat tggtagatga acttgaaaaa ggtcatcata
    12001 taaaagaacg tatctcttta cttgaaaaat aataactatg agagtattaa tgtttgacag
    12061 aaaatttaaa tcttggtaga atagggattg tcgtaaagac aaataacttc ttcttggtta
    12121 caggcatgcc aacctgtcac tcggatgaag ccaaataaaa aggagaaaca tcatggcaat
    12181 ctcaaaagag aaaaaaaatg aaatcatcgc acaatatgca cgtcacgaag gtgatacagg
    12241 ttcagtagag gttcaagttg ctgtccttac ttgggaaatc aaccacctta atgaacacat
    12301 caaacaacac aaaaaagacc acgctactta ccgtggattg atgaaaaaaa tcggtcgccg
    12361 tcgtaacttg cttgcatact tgcgtaaaaa cgacgttaac cgttaccgtg agttgatcaa
    12421 ctctctagga cttcgtcgct aattcaagat acaaaggctg tcaaaagcac aaagtaaaaa
    12481 taggaaaatt tacgaagaaa cttcagtttc taggagattt tatctttttt gccaagtgct
    12541 taggccgtgt tcaattgagc atatcttgat aatgaagcta ctctaaattg ggtagctttt
    12601 ttgtgttgtc accttacctc gatatactca agtataatct ttggttacgg ttcctagcac
    12661 tgtaaggtaa aataaaccag cttttctccc ttcggggaga ttttttttgt ttcactgaaa
    12721 gtttcgtacg atcttcgcct cgtcgcctag tctataaacg atttatctag caagaatcat
    12781 gatgctaagg gcgtcaaaaa tccgtatgaa aatagggaaa tgacacagtg ttcgatgagc
    12841 acaaggagtt tcatcttttt cactaggatt ttagcccgga ctcaaatcag ctctctgact
    12901 tcagagggct tttttattga ggttttatcg gtaacaattt tggagactac aaaaacctca
    12961 aacggtatca gctaattaca ccataaaggt gcgcagttac tcggcttttc aagccgagta
    13021 gttgtatgca agccccctag aagagcccac tctttacaaa gtaaagtata gtatgttata
    13081 ctttacatgg aagtagtcac tgaattccag ttagaaatta ctttgtaact acgttttgag
    13141 gaggagtaaa atgctttcct acgttcgata ttacccacta gcgatagcta aattaatgtg
    13201 tctgtgctct cctaaaatct gctgatttat tactgactaa tacaggagtt ttttttatgg
    13261 gacagacaat catatctgct attggtgttt atatttccac cagtatcgat tatttaatta
    13321 ttttaattat tttatttgca cagctatcac agaataaaca gaaatggcat atttatgcgg
    13381 ggcaatatct aggcacaggc ttacttgtag gggcgagttt agttgctgct tatgtcgtta
    13441 atttcgtgcc tgaagaatgg atggttggat tgcttggttt aatccctatc tatttaggga
    13501 ttcgctttgc aattgttgga gaagatgcgg aagaagaaga ggaagaaatt attgaaagat
    13561 tagaacaaag caaggcaaat caactgtttt ggacagttac attgctgaca attgcgtctg
    13621 gcggagataa tttaggtatc tatatacctt attttgcttc gttagattgg tcacagaccc
    13681 tcgtggcctt gcttgtgttt gtaatcggca taattatctt ttgcgagatt agtcgggtgt
    13741 tatcttctat tccgttaata ttcgagacaa ttgaaaaata cgagcgaatc attgtgccct
    13801 tagtattcat tctacttgga ctatacatca tgtatgaaaa tggcacgata gagacttttc
    13861 tgatcgtgta gatttttttg tttcactagg attttagtcc gagctcaaat cagctctctg
    13921 attttcagag ggctttttca ttgagtataa atggacaatc ttaaagttac tctattgtag
    13981 agtggctttt gatttgatta ggagattctt ataaatatag taaaatgaaa taagaatagg
    14041 acaaatcgat caggacagtc aaatcgattt ctaaaaatgt tttagaagta gaggtgtact
    14101 attctagttt caatttgata tataaatgaa aaccttagct gtttggccaa ggttcatttc
    14161 ttctatgcaa gttcttctct tttcttatct gggttccaga tgaagcttgc gataaagcta
    14221 aagatgatgg ttaggatagc gagaataata gcaaggatga gggcagggat gcggataaac
    14281 caccagagtg gatttggttt tttatcattg tgccattgtt tcgtttcttc gtccagacgt
    14341 tggaattctg tttgaatacg attggcgact gtttcaatgc cttcatcatt cattttcttg
    14401 atatctgaga tatcgattgg atttccaaag ttcatatcga cacgttcacg gctaatcaag
    14461 cccttcaaag tcatgggacc ggtgtaggta accggcatga tacggacctt ggccattttg
    14521 gcaatcagtg ctgcgccccc cttgacatcg tttgagtggc ggctaccact tggaaacatg
    14581 atgagagagc ggtcactttt tttgagaacg ttgataggat atttgatggc tgaggcgctg
    14641 ggattttcac ggtcgatggg aaaggcgcca cacatacgaa tccaccaacc aaagatacgg
    14701 ttggtaaaga gttctttttt tgccataaag atgaactgtt ttggcttggt cgcaaaggcc
    14761 atataaacag gatcccacca ggtacggtga ggcgcaacta aaatataatt ttcatcttga
    14821 ttaggaattt tatcagtatt atgatagtga gcattgccat tgatggacca taagagcaat
    14881 acaactaatc cacgcaaata agtataaaac atgcgatctc cttcgattgt tttcttgtta
    14941 ttattatacc ttatcaaagg agggctggca aacttttccc ttgactagat gcatatttgg
    15001 gatgaaatta gaattctgtt aaaaaaaatg atataataga atttatggat aaaaataaga
    15061 ttatgggatt aacccaaaga gaaatcaagg aaagacaggc tgagggtttg gtcaatgact
    15121 ttaccgcatc agccagtacc agcacttggc aaatcgttaa acgaaatgtc tttacccttt
    15181 ttaacgcttt gaactttgcc attgctttgg cccttgcctt tgtgcaggct tggagcaatc
    15241 tggtcttctt tgctgttatc tgctttaacg ctttttctgg gattgtgacc gagctacgag
    15301 ccaaacacat ggtggacaag ctcaatctca tgaccaagga aaaggtcaaa accatccgtg
    15361 atggtcagga agttgctctt aatcctgaag aattagtgct aggagatgtc attcgtttgt
    15421 ctgcaggaga gcagattcct agtgatgcct tggttttgga aggctttgcg gaagtcaatg
    15481 aagccatgtt aacgggagaa agtgatttgg tgcaaaagga agttgacggc ttacttttgt
    15541 caggaagttt cctagccagt gggtcagttt tatctcaagt tcaccatgtc ggtgcagaca
    15601 actatgctgc caaactcatg cttgaggcta agaccgttaa acccatcaac tcccgtatca
    15661 tgaaatcgct ggacaagttg gctggtttta ctgggaagat tatcattccc tttggtctgg
    15721 ctctcttgct ggaagccttg cttttaaaag gcctgcctct caagtcatcc gttgtaaact
    15781 cgtcgacagc tcttttggga atgttgccta agggaattgc ccttttgacc attacttcgc
    15841 tcttgactgc agtgattaag ttgggcttga aaaaggtctt ggtgcaggag atgtactctg
    15901 ttgagacctt ggcgcgcgtg gatatgctct gtctggacaa gacgggtacc atcacccaag
    15961 gaaagatgca ggtggaggct gttcttccac tgacggaaac ttatggtgaa gaggctgttg
    16021 ccagcatcct gaccagctat atggcccata gtgaggataa aaatccaaca gctcaagcca
    16081 ttcgccagag attccaaggt caagtagtct atcctatgct ctctaatctt cccttctcca
    16141 gcgaccgcaa gtggggagcc atggagttag aaggtttggg aatagttttc ttaggggcac
    16201 ctgagatgtt gctggattct gaggtcccag aagccagaga ggccttggag agaggatcac
    16261 gtgtcttggt cttagctctc agtcaggaga aattagacca tcacaaacca cagaaaccat
    16321 ctgatattca ggctctagcc ttgctggaaa tcttggatcc tattcgagag ggagcggcag
    16381 agacgctgaa ctatctccgt tctcaggaag tggggctcaa gattatctct ggtgacaatc
    16441 cagttacggt atccagcatt gcccagaagg ctggttttgc ggactatcac agctatgtcg
    16501 attgttcaaa aatcacggat gaggaattga ttgctctggc ggaggagaca gcgattttcg
    16561 gacgtgtttc ccctcatcaa aagaaactca ttatccaaac gctgaaaaaa gcgggtcata
    16621 caacagctat gactggggat ggagttaatg atatcctggc tcttcgtgag gcggattgtt
    16681 ctatcgtaat ggcggaggga gacccggcaa cccgtcagat tgccaacctg gttctcttga
    16741 actcagactt taatgatgtt cctgagattc tttttgaagg tcgtcgtgtg gtcaataaca
    16801 ttgcccacat cgctccgatt ttcttgataa agaccatcta ttccttcctg ttagcagtca
    16861 tctgtattgc cagtgcttta ctaggtcggt cagagtggat tttgattttc cccttcattc
    16921 cgatccagat taccatgatt gaccagtttg tggaaggttt cccaccattc gttctgactt
    16981 ttgagcgaaa tatcaaacct gttgagccaa atttcctcag aaaatccatg cttcgtgccc
    17041 taccaagtgc cctcatggtc gtgtttagcg ttctttttgt gaaaatcttt ggaacgagtc
    17101 aaggttggtc tgagttagaa atctcaactc tcctctatta tctcttgggg tcaattggtt
    17161 tcttatccgt atttagagcc tgcatgccat tcactctatg gcgagtcctc ttgattgtct
    17221 ggtcagtagg aggcttccta gccacagctc tcttcccaag aatccaaaaa ctgcttgaaa
    17281 tttcaacctt gacagaacaa acgttgcctg tttatggtgt catgatgttg gtctttacag
    17341 tgattttcat cctgactagt cgctatcaag ctagaaaata aagaaagact gcaatctgtg
    17401 gattgcagtt tttttaggta caagattgcc agccgaaatg tggtataata agaggtaata
    17461 gagttttgga aagtgagaga agatgatttc aaagagatta gaattggtag cttcctttgt
    17521 gtcacagggg gctattttac tagatgtggg aagtgaccat gcttatctgc ctatcgagtt
    17581 ggttgagaga ggccaaatca aaagcgctat tgcaggtgag gtggtggaag gtccctatca
    17641 gtctgcggtt aaaaatgttg aggctcacgg cctaaaggag aaaatccaag tccgtttagc
    17701 caatggcttg gcagcttttg aagagactga ccaagtgtct gtcattacca ttgctggcat
    17761 gggtggtcgt ttgattgcta ggattttaga agaaggtttg gggaagttag ctaatgtaga
    17821 gcgtttgatc ctccagccca ataatcgtga agacgacttg cgtatctggc tacaggatca
    17881 tggattccag attgtagcag aaagcatctt agaagaagct ggaaagtttt atgagatttt
    17941 ggtggtggaa gcaggacaaa tgaagctatc agccagtgat gttcgctttg gtcccttctt
    18001 gtccaaagaa gtcagtccag tatttgtcca aaaatggcaa aaagaagctg agaagctaga
    18061 gttcgctctc ggacaaatcc cagaaaaaaa tctggaagaa cgtcaagttc tagtagataa
    18121 gattcaagct atcaaggagg tgctccatgt tagcaagtga agtgattcat gcttatgaag
    18181 ccttttgccc tcaggaattt tctatggagg gagacagccg tggtctgcaa attggcactt
    18241 tagacaaggg tatccaaagg gtcatggttg ccctcgatat tcgtgaagag acagtggcag
    18301 aggccattga aaagggtgtg gacttgatta tcgtcaagca cgcgcctatc tttcgtccta
    18361 tcaaggactt gcttgccagc cgtccgcaaa atcagattta catcgacctg attaagcatg
    18421 acatcgcagt ttatgtcagc cataccaata ttgatatcgt tgaaaatggg ctcaatgact
    18481 ggttttgtca gatgctagga atcgaggaga cgacttatct gcaggaaaca ggtccagaac
    18541 gtggaattgg acgtattggg aatattcagc ctcagacatt ttgggaattg gcccaacagg
    18601 tcaagcaagt ctttgaccta gatagccttc gaatggtgca ttatcaagag aatgatttgc
    18661 agaagcctat ttcaagagta gcaatttgtg gtggaagcgg gcagtctttc tataaggatg
    18721 ctttggcaaa gggggcagat gtctatatca ctggtgatat ctactaccat actgctcagg
    18781 atatgctgtc tgatggcttg ttagcattgg atccaggtca ctatatcgaa gtgctttttg
    18841 tggaaaaaat cgcagcactc cttactcaat ggaaagagaa aaaaggctgg gaactagaga
    18901 ttttacctag tcaagcatcg accaatcctt tccgtcatat ctagttagaa agtgaagaca
    18961 atgaaaaaag ttgccattat tggagcagga attgtgggag caacagctgc ctactacctc
    19021 tcgagagaaa gtgacctaga ggtgaccgtt tttgaccatg agcaaggtca agccaccaag
    19081 gccgcagcag gaattatcag tccttggttt tccaaacgcc gtaataaagc ctggtacaag
    19141 atggcgcgct tgggggctga tttttatgtg gatttattag ctgatttaga gaaatcagga
    19201 caaaaaatcg acttttacca gcgttcggga gtctttctct tgaaaaagga tgaatccaag
    19261 ttggaagaac tttatcaact ggccctccag cgcagagaag aatctccctt gatagggcaa
    19321 ttagccattc tggaccaagc ctcagctaat gaattattcc ctggtttgca gggatttgac
    19381 cgcctgctct atgcttctgg tggagcgaga gtagatggcc aactcttggt aactcgtctg
    19441 ctagaagcca gtcatgtcaa gctggtcaaa gaaaaagtga ctctgacacc gttagcatca
    19501 ggctaccaga ttggtgaaga ggagtttgag caggttattt tggcgacggg agcttggttg
    19561 ggggacatgt tagaaccctt gggttatgaa gtagatgttc gtcctcaaaa aggacaacta
    19621 cgagattatc agctggtcca agacatggaa gcttaccctg ttgtcatgcc agaaggggag
    19681 tgggatttga ttccttttgc aggtgggaaa ttgtccttag gcgctaccca cgaaaatgac
    19741 atgggatttg atttgacggt agatgaaacc ttgctccaac aaatggagga ggccaccttg
    19801 actcactatc tgattttggc tgaagctact tcaaaatctg agcgtgttgg aatccgtgcc
    19861 tacaccagtg atttctctcc tttctttggg caggtgcctg acttaactgg tgtctatgca
    19921 gccagtggac taggttcatc aggcctcaca actggtccta ttattggtta ccatttagct
    19981 caactgatcc aagacaagga gttgaccttg gaccctgaaa actacccaat tgaaaactat
    20041 gtcaaacgag taaaaagcga ataatactca atgaaaatca aagaacaaac taggaaacta
    20101 gccgcgggtt actcaaagca ctgctttgag gttgtggata gaactgacga agtcagctca
    20161 aaacactgtt ttgaggttgt agatagaact gacgaagtca gtaaccatac ccatggcaag
    20221 gcgacgttga cgtggtttga attggatttt cgaagagtat aagcatttta ctgaaatttt
    20281 atcaggtagt ttaggatggc aaatgacatt ccctgtcaaa aatggtaaaa taagaaaaaa
    20341 taatctgaga atcgaggaaa aaagatgcaa gaaaagattt tggtaactgg tggtgccggt
    20401 tttattggaa cccacactgt tattgaattg atccaagcag gccatcaagt tgttgtggtg
    20461 gataatcttg tcaatagcaa tcgtaagagt ttagaagttg ttgaaagaat cacaggagtt
    20521 gagattcctt tctatgaggc agatattcgt gacacagcta ccctcagaga tattttcaag
    20581 caggaagaac cgactggtgt cattcacttt gctggtttga aggctgttgg cgaatcaaca
    20641 cgtatccctc ttgcctacta tgacaacaat atcgctggaa ctgtcagcct tttgaaagcc
    20701 atagaagaaa acaactgtaa aaacatcatc ttcagttctt ctgcgacagt ttacggggat
    20761 ccgcacacag tgcccatctt ggaagatttc ccactttcag tgaccaaccc atacggtcgt
    20821 actaagctca tgctagagga aattttgact gatatttaca aagcagactc agaatggaat
    20881 gttgtcttgc ttcgttactt taacccaatc ggagcccatg agagtggtga tttgggagaa
    20941 aatccaaacg gtattccaaa caatctcttg ccatatgtga ctcaagtagc cgttggaaaa
    21001 ttagagcaag tgcaagtgtt tggagacgat tacgatacgg aagatggaac aggtgttcgt
    21061 gactatatcc acgttgtcga tttggctaag ggtcacgttg cagctttgaa aaaaatccaa
    21121 aaaggttcag gactaaacgt ttataacctt ggaactggta aaggttactc agttcttgaa
    21181 attatccaaa acatggaaaa agcggtggga cgtcctattc cttaccgtat cgtagaacgt
    21241 cgcccaggtg atatcgctgc ctgctactca gacccagcaa aagctaaagc agaactcggt
    21301 tgggaagcag aactcgacat cacccaaatg tgtgaagacg catggcgttg gcaaagcaag
    21361 catccaaatg gatttgaaga ctaagatgat gatttcaatc atcgtccctt gtttaaacga
    21421 agaggaagta cttcctcttt tttatcaggc tctggaagct ttacttccag atttggaaac
    21481 agaaatcgag tatgtctttg tcgatgatgg atcaagtgat gggaccttgg aactcttaaa
    21541 ggcctatcgg gagcaaaatc cggcagtcca ttatatttct ttctctcgaa attttggcaa
    21601 agaagcagcc ctttatgcag gcttgcaata tgcgacagga gatttggtgg tggtgatgga
    21661 tgcagacctc caagatcctc ctagtatgtt gtttgagatg aaaaatgtac tagacaaaaa
    21721 tgtagacttg gactgcgttg ggacacggag aactagtcgg gagggagaac ccttctttcg
    21781 cagtttctgt gctgttctct tttatcgcct catgcaaaaa atcagcccag tggctctgcc
    21841 gtcgggtgtc cgtgattttc gtatgatgag aaggtctgta gtcgatgcca ttttaagctt
    21901 gaccgagtcc aatcgttttt caaaggggct cttcgcctgg gtgggtttca aaacctacta
    21961 tttggactat ccaaatgtcg aaaggcaggc tggcaagacc agttggagtt ttaggaaact
    22021 ctttttctac tccattgaag ggattattaa tttttcagat tttcccttga ttatagcctt
    22081 tgtagctggt ctcctatctt gttttctttc tctgctgatg accttttttg ttgtggttcg
    22141 gaccctcatt ttgggcaatc cgacatctgg ttggacctct ctgatggctg ttattctctt
    22201 tcttggaggc attcaactct tgaccattgg gattctcggc aagtatatca gtaagattta
    22261 tttagagact aaaaaaagac cactttatct tatcaaagaa aaaagtgatg ataggctaaa
    22321 aaagatagaa tttatctgac atagtcactt tttgttattt gtaattcttt tagttcggag
    22381 tttgggtgat ttttaaaaga attagggatt tgaaatgatt taaaaaatct atgtagacta
    22441 aatttaaatt gtagtgactt aataaataaa aaatttagga gtattatgtt atgctaagta
    22501 aagaggatta tactgaagaa atcgggctaa taaagaaaca aaattatgta gaggctgaat
    22561 tgtatcctat agttgctgat ataattaagc caactttaaa agatagttta tcaaaaagat
    22621 atgtcttcgg aagacaaaga aggggtttgg gacaaattta ttatggtcta agtaattttc
    22681 ctgatatagt tattttagat aagacttatg aaaacaaatc taggaaaagt ataaaaattg
    22741 aagaatggaa gaaacttcga ggatgcgtgg aagttaagaa tttaaattat agtttaatta
    22801 cagaggaaaa aatcaaatca accatatcga acagttttga acatataact ggagagatgg
    22861 aacaactaac tggagagatg ggacaactta ttggagacct tttatggtat aaaaaagtaa
    22921 tttatacaaa tggaattgaa tggagatttc taagtttaga tgacaaggaa gagatagata
    22981 atacaattgt tgaagtagtt aacaaaagaa tagaaacaga agaagcggga aattcttttg
    23041 attggtggaa gaatattaaa gatttatcgt tcaattatac ggatatatgc ctatctaaag
    23101 attgtagaca agagtggaat gaatttgtaa aaagggtaaa ggaaatagaa tggtagaagt
    23161 ctattctcat tgagaaattt agattttaag ttacagtaag atttatttag agactaaaaa
    23221 aagaccactt tatcttatca aagaaaaaag tgaccttcct gattttacag aaaaaaataa
    23281 agtgaaaaga ctataatttt acatggaaat gtgctaaact agagggagtg gattatcgcc
    23341 attgatttag gcttcctggt ttccaatcag ggcgcgagtt gggcaatttt taacagcctc
    23401 taagacatcc tgactaggag aaatttcttt ttccagttgg tcagggtcat cgtaaaaacg
    23461 cacgattcca ttatcgtggt aatcaaataa atcagaataa gtttggcaaa gcccacaggc
    23521 gatacatcgt tcaggtataa gtgtgatttt catgttcata tttatattgt aataagaaaa
    23581 gtaaaaaaaa acaaggagta aggtatggca aaagaaccgt ggcaagaaga tatctatgat
    23641 caagaagaat caagagcaga gcgtcggcat cgaaaccacg gaggggctga taggatggct
    23701 aatcgtattt tgacgatcct agctagtatt ttctttgtaa ttgtggtggt gatggtcatc
    23761 gttctcatct atctatcatc ggggggaagt aatcgcacag cagccttaaa agactttcat
    23821 gattctgatg caagtgtagt acaaatctca tcttcaagca gttctcagcc tgagcagagt
    23881 tcagagccag aatctacttc tagtagttca gaagaagctg ctaatcctga aggaacgatt
    23941 aaagttctcg caggagaagg ggaagcagct attgccgctc gtgcaggaat ctccattgct
    24001 cagttagagg ccttgaatcc tgggcacatg gctacaggat cttggtttgc taatccaggt
    24061 gatgttataa aaataaaata ggagccgata tgaaaacaat tcaaattgct attgatggtc
    24121 ctgcttccag cggtaagagt acggtcgcaa agattattgc taaggatttt ggattcacct
    24181 accttgatac aggagctatg tatcgtgcag cgacctatat ggctcttaag aaccaattag
    24241 gagttgaaga agtcgaagcc cttctagcct tgttggacca gcatccaatc agctttggac
    24301 gttcagaaac tggagaccag cttgtttttg taggagatgt ggatattacc catcctatcc
    24361 gtgaaaatga agtgaccaat catgtttctg ctattgcagc aattcctgaa gtgcgtgaga
    24421 aactggtttc tctccaacaa gaaattgccc agcaaggcgg gattgtcatg gatggtcgcg
    24481 atattggaac tgttgtattg ccacaagcag aattgaaaat tttcctagta gcttctgttg
    24541 atgagagagc agagcgtcgt tacaaggaaa atattgccaa gggaattgaa acagactttg
    24601 aaaccctaaa aaaggaaatt gctgcgcgtg actacaagga tagtcatcgt gagacttctc
    24661 ctctcaaaca agcagaggat gctgtctacc ttgatacaac tggtttgaac attcaagaag
    24721 tagttgaaaa aatcaaagca gaagctgaaa aaagaatgta aatgtagaaa agccgataga
    24781 ttgatatcgg tttttttcta aatttgtcaa aatgctgatt ttagggtata atagttgctg
    24841 ttcgagaaat tttgattttc aaagaatagt gaatgatgat aaggagaaac catgaacaat
    24901 ttaccaaatt gtccaaaatg taactcagag tatgtctacg aagacggtgc cctactggtt
    24961 tgcccagagt gtgctcatga gtggaatcct gctgaagttg cagaagtaga agaaggtctt
    25021 gtcgctatcg atgccaacgg aaataaattg gctgatggtg atacagtaac tctcatcaag
    25081 gacttgaaag taaaaggtgc gccaaaagat ttgaaacaag ggacgcgcgt gaaaaatatc
    25141 cgcatcgtag aaggcgacca caatatcgac tgtaagattg atggttttgg tgccatgaaa
    25201 cttaaatcag agtttgtgag gaagatttaa gcatgtcaaa acactataaa cttgtatttt
    25261 atagccgtat cttcttgttt ctagcggctt ttacgggagt ttatcttgaa attactaagc
    25321 atggtggttt tgggatgctt ctctattaca cggttctgtc caacctcttg gtaactattt
    25381 ttacccttta tcttctaaag gttatgagcc gtgtaggtga aaattggcaa aggccaagtc
    25441 tcttgcgctt aaaaggtggg gtcaccatga gtatcatgat tacctgtgtg atttaccatt
    25501 tcctcttggc gcccattgcg actaatttct ataccctaga aaatttcctt tgccactata
    25561 tcgttcccat ctggttttta gcggataccc tcttttttga caaacagggt caatacaaga
    25621 tttgggatcc agcagtgtgg accattttac cctttctgta tatgatgttt gctcttttta
    25681 atggcttggt tctaaaactc aatattccaa atgccaagga taatcctttc ccttacttct
    25741 ttttgaatgt gaacaagggt tggaatgttg tgtttaagtg gtgtctgatt atctttgttg
    25801 cctatatggt agcaggattt attttctact ttatcaagca aatcaagaga aagtcatcct
    25861 aatactcttc gaaaatctct tcaaaccacg tcagtttcca tctgcaacct caaaacactg
    25921 ttttgaacaa cctgcggcta gcttcctagt ttgctctttg attttcattg agtataagat
    25981 acaagggatt cattttcgaa tttaagaagg agtctacaaa ccaatgaggc ttcttctttt
    26041 cttgcttatt tgataactat caaaaaagta gaagattaag agaaatatag aaagagattt
    26101 catgaaacaa tttttagaac gggccagcat tttggctctc tccctcgttt tgattacctc
    26161 cttttccatt tcgagtgccc taccagccat gtttgactat tatcagggtt attctaagga
    26221 acaaattgag ctcttggtga gcttgccttc ctttggaatc atgatgatgt tactgctaaa
    26281 tggtttctta gaaaaaatat ttcctgagcg cttacagatt agtttgggct tgctgatttt
    26341 atcattgagc ggtacagctc ccttctggta ccaagcctat ccctttgtct ttggaacacg
    26401 gcttctcttt ggtttgggtc ttgggatgat caatgccaag gccatttcta ttatcagtga
    26461 acgctaccaa ggaaaaaggc gaattcagat gttagggcta cgcgcttctg cagaggtcgt
    26521 tggagcttct ctcattacct tggccgtcgg tcagttgttg gcctttggtt ggacagctat
    26581 ctttctagcc tatagtgctg gatttttggt gctgcccctt tatctgctct ttgtccctta
    26641 tggaaaatca aagaaagaag tcaagaaaag agcgaaggaa gcaagtcgtt taactcgaga
    26701 aatgaaaggc ttgattttta ccttagctat cgaagcggca gttgtagttt gtaccaatac
    26761 agctattacc atccgtattc caagtttgat ggtggaaaga ggattggggg atgcccagtt
    26821 atctagtttt gttcttagta tcatgcagtt gatcgggatt gtggctgggg tgagtttttc
    26881 tttcttgatt tctatcttta aagagaaact gctcctctgg tctggtatta cctttggctt
    26941 ggggcaaatc gtgattgcct tgtcttcatc cttgtgggtg gtagtagcag gaagtgttct
    27001 ggctggattt gcctatagtg tagtcttgac gacggtcttt caacttgtct ctgaacgaat
    27061 tccagctaaa ctcctcaatc aagcaacttc atttgctgta ttaggctgta gtttcggagc
    27121 ctttacgacc ccatttgttc taggtgcaat tggcttacta actcacaatg ggatgttggt
    27181 ctttagtatc ttaggaggtt ggttgattgt aatctctatc tttgtcatgt acctacttca
    27241 gaagagagct taggattgat tcctaagttt ttcttttgat actcaatgaa aatcaaagag
    27301 catagttgat tgagtttgga atagtacgct gtagctgcta aaatatttct agaaattaat
    27361 ttgacttttc taatagagtt attcatatct tatttcaatc tactatagaa agctagccgc
    27421 aggttgctca aaatagtgtt ttgaggttgc agatggaaac tgacgtggtt tgaagagatt
    27481 ttcgaagagt atgagatttt tatacccata caatatttgt tttaggtcct tgtttacaga
    27541 ctaatttctt gataaaatag aggttatgac gagatataaa gcaactattt cctatgatgg
    27601 ttatgccttt gctggctttc agcgccagcc tcatgcgcgt agcgttcagg aagaaattga
    27661 aaaaaccttg accagattaa ataaagggca agccattact gttcacggtg ctggtaggac
    27721 agatagtggg gttcatgccc tgggacaggt cattcatttt gacctgcctt atcagatgga
    27781 tgaggagaaa ctccgttttg ccttggatac ccagtctcct gaagatattg atgtgatttc
    27841 gattgagctt gtggcagatg attttcattg ccgttatgcc aagcatagca agacctatga
    27901 gtttactgtg gatagaggac gtcccaaaaa tccgatgcgc cgtcactatg ccacccactt
    27961 tccctaccca ctcgatgtgg aacgaatgca gattgcaatc aaaaagctag agggaaccca
    28021 tgattttacc ggttttacag cctctgggac tagtgtagag gataaggttc gcaccatcac
    28081 agaagctagt ttaatagtcg atgagacagg acaatttttg acctttacct tttcaggaaa
    28141 tggtttcttg tataaacaga ttcgcaatat ggtggggact cttctcaaaa tcggtaacaa
    28201 ccgcatgcca gtagagcaga ttgatctcat cttggagaag aaggacaggc aacttgcagg
    28261 tcccactgca gcaccaaatg gtttgtattt aaaggagatt cgttatgaag aataatcgta
    28321 ttttagcact ttctggaaat gatattttta gtggtggtgg actgtcagct gatttggcta
    28381 cctatacctt gaacggcttg catgggtttg tagcagtgac ttgtttgaca gccttgacag
    28441 aaaaaggatt tgaagtcttt ccaactgatg ataccatttt tcaacatgaa ttagatagct
    28501 tgcgtgatgt ggaatttggg ggaattaaga ttggtcttct ccctactgtc agtgtggctg
    28561 agaaggcctt ggactttatc aaacaacgcc caggagtacc tgtggtgttg gatcctgtct
    28621 tggtctgcaa ggaaacgcat gatgtagctg tcagtgagct ctgccaagag ttgattcgct
    28681 ttttccctta tgtcagtgtg attacgccta atctcccaga agcagaatta ttatccggtc
    28741 aggaaattaa aaccttggaa gacatgaaaa ctgcagcgca gaaattgcat gatttaggag
    28801 cgccagcagt cattatcaag ggaggcaatc gtcttagtca ggacaaggct gtggatgtct
    28861 tttatgatgg acagaccttt actatcctag aaaatccagt tatccaaggc caaaatgctg
    28921 gtgcaggttg tacctttgcc tctagcattg ccagtcactt gattaaaggt gataaacttt
    28981 tgccagcagt agaaagctct aaggctttcg tttatcgtgc tattgcacaa gcagatcagt
    29041 atggagtaag acaatatgaa gcaaacaaaa acaactaaaa tcgcccttgt atccctatta
    29101 accgcccttt ctgtggttct aggttatttc ttaaaaatcc caacacctac aggaattcta
    29161 actcttttag atgctggtgt cttctttgcg gccttttact ttggtagtcg tgaaggagcg
    29221 gtagtcggag gactagcaag tttcttgatt gacctcttat caggctaccc tcagtggatg
    29281 ttctttagct tggtcaacca tggcttgcag ggatttttcg caggatttaa aggaaaaagt
    29341 cagtggttag gccttatttt agcaactatt gccatggtag gaggctacgc cttgggttct
    29401 actttgatga atggctgggc agcagccctc ccagaaattc taccaaattt catgcaaaat
    29461 atggtaggga tgattgtagg atttattctt agtcaaagta tcaagaagat taagtaatac
    29521 tcttcgaaaa tctcttcaaa ccacgtcagc ttccatctgc aacctcaaaa cactgttttg
    29581 agcagcctga ggctagcttt ctagtttgca ctttgatttt cattgagtat aaagaggttg
    29641 agtaaaaagt atttcaaata agaaaaacgc atagtatcag gtgttgaatg aactgccccc
    29701 caaaaagtta gacagaaaaa atctaacttt ttggggtgtt tttattatga aattaa
//
LOCUS       DAVBIC010000027        28617 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.027, whole genome shotgun sequence.
ACCESSION   DAVBIC010000027 DAVBIC010000000
VERSION     DAVBIC010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 28617)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28617)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28617
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.027"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            complement(482..2209)
                     /gene="ezrA"
                     /locus_tag="VQ664_001153"
     CDS             complement(482..2209)
                     /gene="ezrA"
                     /locus_tag="VQ664_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HET2789320.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKASHQIDQIESQITLIEEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLEAGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPTQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(2291..4237)
                     /gene="gyrB"
                     /locus_tag="VQ664_001154"
     CDS             complement(2291..4237)
                     /gene="gyrB"
                     /locus_tag="VQ664_001154"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HET2789321.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAD
                     LEVVGDTDRTGTTVHFIPDPKIFTETTTFDFDKLNKRIQELAFLNRGLQISITDKRQG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(4252..4815)
                     /locus_tag="VQ664_001155"
     CDS             complement(4252..4815)
                     /locus_tag="VQ664_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET2789322.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEDILNQGGRHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(4900..5454)
                     /locus_tag="VQ664_001156"
     CDS             complement(4900..5454)
                     /locus_tag="VQ664_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HET2789323.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGDLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYRDVFGKNQ"
     gene            complement(5465..6688)
                     /locus_tag="VQ664_001157"
     CDS             complement(5465..6688)
                     /locus_tag="VQ664_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HET2789324.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVSLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(6725..9175)
                     /locus_tag="VQ664_001158"
     CDS             complement(6725..9175)
                     /locus_tag="VQ664_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HET2789325.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLREKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKTAASLEPRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPVSLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SQSLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEGFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSGRTLLSSL
                     LPESCQAMGVSATLEISQRVSLADLLGYPEAKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPFVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIIGKRYGKQIVASLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(9374..10303)
                     /locus_tag="VQ664_001159"
     CDS             complement(9374..10303)
                     /locus_tag="VQ664_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HET2789326.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELLVAVNALMHQDMMDRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARSLIQEGNFSH
                     DQAFLLDEEVRKLHPKNRFLDTGFYDYDPDMVK"
     gene            10443..10730
                     /locus_tag="VQ664_001160"
     CDS             10443..10730
                     /locus_tag="VQ664_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HET2789327.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(10764..12098)
                     /gene="ciaH"
                     /locus_tag="VQ664_001161"
     CDS             complement(10764..12098)
                     /gene="ciaH"
                     /locus_tag="VQ664_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HET2789328.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(12088..12762)
                     /gene="ciaR"
                     /locus_tag="VQ664_001162"
     CDS             complement(12088..12762)
                     /gene="ciaR"
                     /locus_tag="VQ664_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HET2789329.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
     gene            complement(12871..15417)
                     /locus_tag="VQ664_001163"
     CDS             complement(12871..15417)
                     /locus_tag="VQ664_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HET2789330.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHIAYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEASQVASQIFATHKENLAGLPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
     gene            complement(15541..15981)
                     /locus_tag="VQ664_001164"
     CDS             complement(15541..15981)
                     /locus_tag="VQ664_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HET2789331.1"
                     /translation="MIPQEMWNKYKQINPLIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDVILDSQNQSVCIVEITKVSVELFNQVSAQHAFKEGE
                     GDKSLAYWRQVHEDFFTDCLGEVGLTFTPESKVVLEEFRKVYPL"
     gene            complement(15956..16825)
                     /locus_tag="VQ664_001165"
     CDS             complement(15956..16825)
                     /locus_tag="VQ664_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-utilizing enzyme, TIM barrel domain protein"
                     /protein_id="HET2789332.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQQFVKDYLETICSLYSDEEVWYRFTELTNTEANCLVGTKEFFDEGHPLFGYRGTRRL
                     LACLDEFQAEAHVVTEVYQTNPNLSVIFPFVNDADQLKQAITVLRQYGFTGKVGTMIE
                     LPSAYFDLSSILETGISKIVVGMNDLTSFVFATMRNSQWHDLESPIMLDMLRDMQDKA
                     RKNKINFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            complement(16867..17595)
                     /locus_tag="VQ664_001166"
     CDS             complement(16867..17595)
                     /locus_tag="VQ664_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2789333.1"
                     /translation="MELFKTWKKNMVLYGLKSQIGTVYRNNDRTTSFYDVGNFLYLAG
                     ELDSRFWEDFVRKYGLDYKIIISENTNWQDFLHRKVGLNSFTRYSFKDKANFQVEFLN
                     NLVTHLEEGYNIVPIDNHIYNCFSTEEWSQDLQGDFESYQDFVLKGGFGFVILKNNEL
                     IAGISSGLVYRKAVEVEVATRPNEQGNGFAKKLGAAMILESLNRDMFPLWDAHNEASK
                     KVAEFLGYELSEPYEAFELEEILI"
     gene            complement(17603..18082)
                     /locus_tag="VQ664_001167"
     CDS             complement(17603..18082)
                     /locus_tag="VQ664_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET2789334.1"
                     /translation="MEIKKHFGVYAVCLENGKLLCIEKTRGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETGFTVRSYSNPRIYDVFVREELTNFMVDHVMALYDVEMNESAPQV
                     TTSEAVSDGANDSLGYIWMDIQEITEENASPLVLKVKSELLGFPELDKTSYMNWKVK"
     gene            complement(18093..18791)
                     /locus_tag="VQ664_001168"
     CDS             complement(18093..18791)
                     /locus_tag="VQ664_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HET2789335.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDF
                     HFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDDYKPLLEQTAQDIQEIFEINYIIPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
                     QVFGIAPGAVKTAMTAADFEPGGLADWVASETPIKRWIEPEEIAELSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            complement(18784..19050)
                     /locus_tag="VQ664_001169"
     CDS             complement(18784..19050)
                     /locus_tag="VQ664_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HET2789336.1"
                     /translation="MKNVELKEKNMTFEEILPGLKAKRKYVRTGWGGAENYVQLFDTI
                     EQNGLALEMTPYFLINVSGEGEGFSMWSPTVCDVLATDWVEVHD"
     gene            complement(19116..20042)
                     /locus_tag="VQ664_001170"
     CDS             complement(19116..20042)
                     /locus_tag="VQ664_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HET2789337.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFNLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCQLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSRAANFSLTRKEWYEIYLAAGNNLP"
     gene            complement(20117..20932)
                     /locus_tag="VQ664_001171"
     CDS             complement(20117..20932)
                     /locus_tag="VQ664_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789338.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWESFNLAGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILVLAV
                     LRYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVATILRRSLVQDSPKMKIGTYI
                     VVGTIVLLVVLGYVGMASFIQEGAFYIPAPWDSLSVFTISLVIGIWNWKEAVFRPFVS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFVLFRGFKKIKWSEV"
     gene            complement(20936..21256)
                     /locus_tag="VQ664_001172"
     CDS             complement(20936..21256)
                     /locus_tag="VQ664_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HET2789339.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLTKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
     gene            complement(21553..21633)
                     /locus_tag="VQ664_001173"
                     /pseudo
     CDS             complement(21553..21633)
                     /locus_tag="VQ664_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(21677..23674)
                     /gene="metG"
                     /locus_tag="VQ664_001174"
     CDS             complement(21677..23674)
                     /gene="metG"
                     /locus_tag="VQ664_001174"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HET2789340.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPDGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLAKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEIAYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIVAN
                     LKPRKMMKKYVSQGMILSAEYDGKLTLLTVDPAVPNGSVIG"
     gene            complement(23798..25057)
                     /locus_tag="VQ664_001175"
     CDS             complement(23798..25057)
                     /locus_tag="VQ664_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2789341.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSAFTVSGKEEEVPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKKSKIYGFGGLP
                     ITTNISLAANFNIDEIASIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESV
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            complement(25059..25760)
                     /locus_tag="VQ664_001176"
     CDS             complement(25059..25760)
                     /locus_tag="VQ664_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2789342.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            complement(25744..26943)
                     /locus_tag="VQ664_001177"
     CDS             complement(25744..26943)
                     /locus_tag="VQ664_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HET2789343.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTAVKDE
                     PTHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVAKADRHINELNQARNEAASAQAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILIPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KADEATN"
     gene            27229..28575
                     /gene="gor"
                     /locus_tag="VQ664_001178"
     CDS             27229..28575
                     /gene="gor"
                     /locus_tag="VQ664_001178"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HET2789344.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFDFATLRRNREAYIDRARSSYDGSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESIAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RTNLPLHTHKVPVKLEKTTDGITIHFEDGTSHTASQVIWATGRRPNVKGLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGIYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFASMYSACTRNRQESRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMGATKADFDATVAIHPTASEEFVTMR"
BASE COUNT         8559 a         6298 c         5109 g         8651 t
ORIGIN      
        1 ctatcctatc ttctagaatg tcttccaaac gagaaaactc tcgtaaacaa agaggtttta
       61 gaggcctatt taccgtggac taaagttgta caagaaaagt gcaaataaga aatctccaga
      121 ttaggaacta tccgtgagtt ctctagtctg gagatttttc aatagacttc gttattggac
      181 ggttaccaag ttacttcaaa gtacagattt gaagctgcag ataagactga cgaaatcact
      241 ttaatactaa atgaaaatca aaaagcaaac taagaagcta gcctcaggct gtacttgagt
      301 acggtaaggc gacgctgacg tgatttgaag agattttcga agagtataaa acactgtttt
      361 gaagtggtgg ataaatcggc tgggtaaaaa ctcaatctca ggagaaaatg aagtaaatct
      421 ccccacaact atagaaaaag atttgattct gctcctcaca caataaaatc tttttctttt
      481 attaaaaacg aatcgtttca cgtgttttct catatgaggt aacaaagcga ttggttacac
      541 caggctctgc cacttccaat gcttgagaaa tcttgtcaaa tgaagcgtga taatcaaatt
      601 ctttttcaaa aatatctaaa gcttcgttaa atgcttcttg aatgcgttca tcaaatgagc
      661 gatagcggtt agaatattgc aagagttgct ctgtcaaagt tgcatattgt acaatattat
      721 aagtttccgt ttctaaagct tccatatcat tcgttgcaat ttcaagaact cgggtaacag
      781 attcaatgtt aatcattttt tgttctaact caaccattaa atcctcggta ttattgcttg
      841 ccgtaaagaa taacttcaag aaagtttgtg gaatacctgg cagattgcgt ttttccatgt
      901 atcgcttgat agtatggaga cgattgacat aaacattggc cttttgacgt gcattaatat
      961 catctttctc aatttgtgtc aggcgctcac taactgaaat ttgctcatct tcaatatctt
     1021 ttagttgagt ttgtaaatcc tcaagatttt cttcaagaac tgaataagct tgggttggtt
     1081 cttcttgatt tgaagttacc tcaacaatag ctgcctcaaa actctctaat tctgtctgaa
     1141 tacgacgaac atggcttgca gctgtctcag gaagtaaata ggtcttgttc aaacgtgcaa
     1201 tatcttctcc caataaagta ttattctctt tcatatgttg aaggtaagtt ggaagagttg
     1261 caagtagatt ttccactact ttctgagcag caatttctcg agtaaaaata tcatacaagg
     1321 cattgatttc ctcttgtgcc tgtccattct catattcggc attatccaat tccaactgac
     1381 gaatattctc ttggtttttc ttgaatgctt cataaagcaa gtggaaacgc gcttcaatat
     1441 ccgtttcaac aaaatgataa ttagcatcaa ttagtttacg ataaccggct tccaaatcct
     1501 gtaattgatc tggcaattct gtagaaagcg tcgtaaccaa ggctggaaca cgatccacaa
     1561 tatgacttaa ggccaaaatg tgattttctg tattatccaa aatcactgcg gcttccacag
     1621 ggtcacccga tgaattcaag gttacaaatt gtgaaaattc agattggata ttttctaatt
     1681 gtttttcaat ttcatccaag gcttgaccat actgttctga attttcagca actctatgct
     1741 gaagttcctc aaataaatcc aaagcatgaa gaacacgacc actattttta gattcttgct
     1801 tctctaagtc tgccaaagca ttgcgaattg ccgcaatatc ttcttcaatc aaagtaattt
     1861 gactctcaat ttggtcaatt tgatgactgg ccttgagaaa acgaaatgaa tggttataac
     1921 cttctgcttc aaagagatta ttttcaatat cggcaaaaga gttgagagat aaatcgaccc
     1981 atttttgatt ccattcacgg aaagccactt gactttgtcc aatcaagtgc atatttttta
     2041 cagcttctac ttcatcattt actggaagat tgtatagttc ttcttttctt tcttctagcg
     2101 cctctaatct cccctcgttt cgcttacgta gaaagattgc cactacataa gccagaacta
     2161 aaatgactgc aattgcaacc attaaataaa ttagttgtcc attagacata tcaaactcct
     2221 tttttacttg aaacaatcgt aacgattata tcatattttt tagaccaagg gaactacttc
     2281 tccctatttt ttagacatca agtgtactat agacagcatt ttcttcgata aactcacgac
     2341 gaggctctac tcgatccccc atcaacatat caaagatttt atctgcttct gcagcatcat
     2401 ctacagaaac tctagccatc aagcgatgtt cgggatccat ggttgtttcc cacagctgat
     2461 gatcgtccat ttcacctagc cccttataac gctgaatagt cggtttggta cgaccttcac
     2521 tataacgggc taaagcttct tggagtttga tttcttgatc tgcacccggc tggatatatt
     2581 ctttaatctc gcttccaacc ttgacaccat agattggtgg ttgggcaata taaacataac
     2641 cagcttctag gattggtttc atataacgat aaatcaaggt taaaagaagg gtacgaatat
     2701 gggctccatc gacatcggca tcggtcatca aaacgagttt ttggtaacgg gctttcgaaa
     2761 catcaaattc tgcgccaaat cctgttccca tggctgtgaa aagactacga atttcttcgt
     2821 tagctagaat cttatccata cttgcttttt caacgttcaa aatcttaccg cgaattggaa
     2881 ggatagcctg aaactcacgg ttacgaccag atttggctga tccaccagct gagtctcctt
     2941 cgacgatgaa gagttctgtt tcagcagggt tattagaaga acagtctgct agtttccctg
     3001 gaaggttgga aatttccaaa ccagattttt tacgtgtgac ttcacgcgca cgcttggcag
     3061 ccacacgagc cttggcagct aaaatccctt tttccacgat acgtttggca atctgtggat
     3121 tttccatgag gaaatcggag aaggcttcac tgaagaggcg attggtaatc ttgaccactt
     3181 cgctatttcc caatttggtc ttggtttgtc cttcaaactg tggatttggg tgtttaactg
     3241 agataactgc agttaatcct tcgcgaacat cttcccctgt taaattatct tcattgtctt
     3301 tcagtaactt attcttacga gcataatcat tgataacacg agtcagtgcc gtacggaaac
     3361 cttgttcatg cgttccacct tcatgggtat gaatattatt ggcgaaactc atgacatttt
     3421 catggtaacc tgttgtgtac tgcatggcta cctcaactgt gatatcatcc atctcaccgt
     3481 ctgtatagat tggtgtatca aagattacat ccttgttctc gttgatatat tcaacgtaac
     3541 tagcaatccc accttcataa tgataatgct tggtttgttc caaaccttgg cgcttatcag
     3601 tgatagaaat ttgaagaccg cgatttagaa aggccaactc ttgaatccgt ttatttaatt
     3661 tatcaaaatc aaaggttgtt gtttcagtaa agatttttgg gtccggtatg aagtgaaccg
     3721 ttgttccagt tctatctgta tccccaacca cctcaaggtc tgcaacaaca tgaccacgac
     3781 ggtattcttg gtaatgaatc ttaccgtttt tatggacatg aacgtctaat tgagtggaaa
     3841 gggcattaac tactgacgac cccaccccgt gaagaccacc tgaaaccttg tatccaccac
     3901 cgccgaactt tcctccagca tgaaggactg taaagacggt ctcaacagca ggacggcctg
     3961 ttttttcctg aatatcgact gggataccac gcccatcatc cacaacagta atcgaatcat
     4021 ctggctcaat aaaaacttga atatggctgg caaatcctgc caaggcctcg tcaattgagt
     4081 tatcaacaat ttcccagact agatggtgaa gaccttcttt tgaggttgat ccaatgtaca
     4141 tccctggacg catacgaaca gcctctaagc cctctaaaac ttgaatttga ctggcatcat
     4201 aatcctgtgc ctgcagattt ttgatttctt ctgtcatctt attccttttt cttatatgtc
     4261 taatacttgt cttaaattca cgatactggt aaacaagtgg gtatcaagtc ctgcagcttg
     4321 acctgcttcg atatcaatcg gccgatcacc aatgacaaga ccagagctaa tctgatactt
     4381 ttctcttaaa taaagcatgg attcgggatt tggctttctc ttaaagcctg agctagaagt
     4441 caccacttct gtaaaataag ctgctataga ggttttttct aaaatttcca aaacctgatc
     4501 atttcgatga gagaccaaaa aatgacggcc accttgattt aaaatgtctt ccaataggtc
     4561 agaaactcct tcaaataaaa tcgggtgttc aagctctctg gcttcatttt ccttgtactt
     4621 ttctaaaaaa ttctctaaat tgggagcgaa tgtctcaatc gcaaaaggag tagaaacctt
     4681 taaagcttga tagacactgt catggtcttg tgtgatacca tacagtgcca atgtttcaac
     4741 aaatgcagct gttgaagttt cataattatc cagtaaagtt ccacctaaat cccagatgta
     4801 atcgtgatat ttcataccct tcattatagc atttttttat gaaaaaagcg atgatttccc
     4861 tgagttttcc acataaaaaa cgagagaata actcccgttt tactgatttt taccaaagac
     4921 atctcgatag agcattcctg ttcgtaaact ctctgcgtcc cctcctagtt gctccaccaa
     4981 ctcgtaggca aaggcaaggg ctgttgaagg accccgactg gttgtcaact gaccatctac
     5041 cactactgtt tccttgacgt agtgaccatc aaggatttgc tcttgaacgc cgtcataaca
     5101 agtgtatcgc ttatttttca atatctctgc ttgattgagg gcaattggtg ccgcacaaat
     5161 ggctgctagt ttcttccctt cttgctcgaa gctttgcaat tcttgaatca aggtctgatt
     5221 atcacgtaaa tgtgcagaac caggcatacc tccaggaaga acaatcatat catagtctga
     5281 taaatctcca tcaaagacat gatctgctct tacttggatt gcatgcgaac ccgttacttg
     5341 ctcttcaaaa ccaaccatat cacatgtgat attggctcga cgcaagacat ctacaactgt
     5401 caaggcttca atttcttcaa agccctgagc taacataact gctactttta ccatgatttt
     5461 ctccttattt aatttgtttt aatacaacct ttttccgttt gaatgggact tttccgctct
     5521 tttcttcagc tagattagtc tggtaactca tcgataaaag caaaccaaca ccaatcagat
     5581 tactgataat agctgatccc ccttgcgaaa tgaaaggcaa gggaatcccc gtcaaaggaa
     5641 gtagtccagt cacagcaccg atattctcaa agatgtggaa gagcaacatc ataatcaaac
     5701 ctgtggaaat ataagtgtag aactggttat ttgatttaag agtaatcttc aacatacggt
     5761 aaatcaacat gagatagagg gcaataacca ggacagagcc aataaagcca aaatcttctg
     5821 caataaccgt aaaaatcata tctgactctc gaactgggat aagcagattc gaagcattaa
     5881 atccctgacc aaataagcca ccactcccaa tggcaatctg cccttgagcc tgctggtaag
     5941 tcgttgtttg ggcaaactca aagggattga gccaagccaa aatccgattg atttggtagg
     6001 tcggcattcc aatctggtga agaaaagctc gtccgtcctt gctaataaag atagctaaga
     6061 aaccagcaac tcctgttaca gcagtcacaa atactgggat aataattttc caagaaaccc
     6121 ctgataataa aacgattcct gagaaaatgg ctacaaaaac caaagccgtc cccaagtcac
     6181 tttgaagtgc taaaagaact aggactggaa tggtaaagag aatcatccag aaaattaaca
     6241 aaaagtccag cgaaaccgtg cgtctccatt ccttatgttt ctttgtaaat tggacaatga
     6301 cacgagccaa catgaggata taggatatct tcataaattc tgacggttga aatagggtaa
     6361 ttccatttat tgatacccag tttttggcac ccgttgatgc aactaagctt ggattataaa
     6421 atacaatcgg caagatcata agtcccaagc ctaaaatata tagaaagggg gtcaccttcc
     6481 aaagaaattc tgtattaaag agcatgacca caaaaccaat cacaagcccc aaggcaatcc
     6541 aggcgacctg ctgccctaaa atgggcagaa tattattggg ataatcatga ctaacggcta
     6601 tatagatagc caccacaccg atgaccagta gaaaaaatac tggcaagagc aaactataat
     6661 cgactctaga gtcgagagaa cgtttcatat atactaacct tatactttca tacaatacta
     6721 tttatcaaag ttcattaaaa aatctatcaa tagcctcgtc aacttcggat cgagagatgg
     6781 ttttaacagt cgcttcttct gctagagatg ctactatttg tttgccgtat cgttttccga
     6841 tgattctcct atccaaaata agagttaagg aacgttggta ttcacgtctc atacttcttc
     6901 ccaaagcctg ttttaaacga ataatggcca ttggcaattg ataatcataa aaggcatttt
     6961 tcccttcttg attcagttct tgattaatct ttttcgtcaa gggttcttga ggattttgga
     7021 aaggaagcct cggtacaact tgaatcacaa aaggatggct tgaaaaatca actccctccc
     7081 agaaacttgc tgcaccaagc aagatttgtt gttcaccttt ttcaaagcgt ttctttagct
     7141 gatgaacatc cccattttta tactgggcca agtggctaac tgtaagtaaa tccgatactg
     7201 ctagaagcat gtctttagcg gtaaagagaa ccaaaatcgg ttgctggaaa gcttgaattt
     7261 ccactagtaa agcagctacc tctctggcat agacttctaa ggaggtttct gttaccagag
     7321 ggaaatcttt gaccataacc acttcttgtt cctgttttcc ccgagattca atcttgacaa
     7381 atttggcttc aggatagcct aaaaggtctg ccaaagaaac cctctgacta atctcaagag
     7441 tagccgatac tcccatggct tggcaactct caggaagtaa agaggacaga agagtacggc
     7501 ctgattttgt agaagaaatc tgaattttct tttgactcgt ttcagttact tcaagccagt
     7561 aatcaccttc agctgtaaaa tagcgaacca gctcatcaaa gccttctact tctaattctg
     7621 aaaaatactg atggagattg tccagagaat ctaagatatt tttcctagat ttaccagact
     7681 gaaattgttc tatcaagtag agacactcaa agcgaatact ttctagtatc cgttgttgaa
     7741 ccctgttttc ttctcctact aaagccttat caattaaatc gataatagat tgtatatcgt
     7801 aggtctcttg aagcagattt tctagagcta acaaaatctt ttggacttca tcaataatca
     7861 gtaaacggtc actgacaaat tcaggattat cttcaagtct ggtcacgaga taggcatgat
     7921 tagtcactaa aagcttgcaa gtctctgccc tttcttgact acgtttccaa aaatcttccg
     7981 tcacaaataa gctctgggat gataaattcc catcatgacg aaggtctgct agaaaatgtt
     8041 ggtaacgata gagttgcccg atttcatcca aatctcctgt ctctgtctca gtaagccaga
     8101 ccaagacttg cattttaaag cgtctaaata agcgattttc atcattttcc tgcaaggaat
     8161 gataaaaggc atccaacttc agataatttt gtggtccctt taagctatga atatctgtat
     8221 ggaacacttc cttgaggcgt ttaccttctt cttccatgat ttgattttga agaatctttg
     8281 tcggaacact aagaacaatt tgtcgctctt tggattgaga taaagcgggt aagagatagc
     8341 cataggtttt cccaatccct gtcggcgctt gaatcagaga gacaggttca tctttcaata
     8401 gcaagccaac ctctttagca aaactttctt gttcctccct cacttcaagg ttcaacagag
     8461 aaatattttt agaaaagtct tgagatagtt ttcgtggctc cagagaagct gccgttttct
     8521 taaaatacag accttgaact tggaccaagt ctggagaact caggatagat tggttgcgat
     8581 aagtttcctc aataaccagg taggactcat ataggagagc gtcagccatt tccagcaagc
     8641 gttccaagag acctttagga agctgagtca tcttttcccg taaaaaaaga agtaattctg
     8701 ctgtagcttg ggcatctgaa agggctgtgt gtgcgtgttt aagaggaatt cctaattctc
     8761 gacacaaaat cggcaagcta tatttttcca gttcagggaa aaagacctgg gccaattcga
     8821 ccgtatcaac acgagggttt cttagctcat agccttcaaa aaataaattt tccgccaaga
     8881 gattagcatc aaactgaaca ttatgggcta caaaaatccc atcctccacc aagtcaaata
     8941 tttttctggc aacttgcgaa aaatcaggtg cttgcgccag acgttggtct gtcaatcctg
     9001 tcagttcttt gatatgagca tccaagggtt catgtggatt gacatccgtc gtatagtgat
     9061 cgacgatttc tccgtcctca atcacgacaa ttcccacttg gataatttta gccttactac
     9121 ctgtgctagt tgcctctaaa tccaccacaa catagcgatt accaatcgtt ttcattataa
     9181 aaaattatac caaaaaaagg gccatttggc acctgcaaac ataggataat tttcaaactc
     9241 aagaacacta cttttcttaa aaatcccatc gaatagagca ttctagcctg ctgatttttt
     9301 aaaatagtga agaaatacga aaaattgaga gaagaaatgt tttcatcttc cttctctcaa
     9361 cgaatcatgt attttattta accatgtcag gatcgtagtc ataaaatcct gtatcaagga
     9421 aacggttttt agggtgaagt ttacgaactt cttcatccag caagaaggct tggtcatggc
     9481 taaagttgcc ctcttgaatc aagctacgcg cttggataaa gagttttgca atctcaacaa
     9541 agttctgacc aggagtgtag agcccttcta gtttccagcg agtaaagcca tgctccacca
     9601 attctgttaa tttgatcatc aaatcaaggt cattgttggc aaagatatgg gtcccatgat
     9661 tatcttcaaa aatggaatag tggctctctg gatcacttgg ctcagccaag aagaggtcac
     9721 gtttatgcgt cttttcatca tcgatatgtg taaagttata gtagttttgc aagagtggac
     9781 gtttagaatg atggatgacg ctagcaccgt aaaccaaaac ttcagcagga atttccaaaa
     9841 tctctggcat tttgaaaagt tcagctgatg gaatttcacg cgccaaaaca gcctcagatg
     9901 cgccagcctt ttgtccccag aagttaatct gacgactgct agttaccatg gttgaagcat
     9961 cgtagatggt cttaaatgaa taaccatcgc ggttaactac gtaaaagacg cctgcatccc
    10021 caatcgtaat atagtctgtc ttgatttctt ccaagaagtc taagaaaggc ttgatacggt
    10081 ccatcatatc ttggtgcatg agagcattga ccgcaacgag caattcctta ccagcatcat
    10141 gaaccaactt agcgatttca cgtaattggt cataactaaa ggtcgttggc agacgaaggc
    10201 caaaatcttt ctcaccgaca tagatacggt ctacgccagc ttcgagtagt tgttcaactt
    10261 gttcaatact ttcagcagtt gctgtaatga caatcttttc cataagaaaa attataccac
    10321 atttctccaa aatcatccat gctttgaaaa tgaaaaggga ctttattctt tttgtaacct
    10381 ttctgtaata attctctgcc gaaaaaatga taaaataggt atgtactgtt aaggagagaa
    10441 ttatgcccgt aagaaaatta caatcctatg aggtagacta tcaagaagaa ttaaaccagc
    10501 agcttcctca ttaccaagct tatacacctg aagcgcaatc tgatgccaat ctcaaggaaa
    10561 tcctattttt tattaatatc gctgtttttt gtatctgtat tgctatcttt agttttatct
    10621 ttttagcatt aaaattatca actgctcttg cctttgccgc agcaatcgga ttcagcttac
    10681 ttgttttaaa agttcaacgg tctattatca aacgaaaacg tagaagataa atccaaaata
    10741 tcgccccagt tggagcgata tttttatttt ttctttttag atggtgtctg aatggcaatc
    10801 ttcacttcaa agattgttcc cttgggttta ttatctttga cagtaacagt tccttttaga
    10861 gcatctacaa tttgcttggc tagggataat cctaaaccaa aaccaccttt ttgccgagtt
    10921 ctagccttgt ctactcgata aaaacggtca aaaattttct ttttatcttc tgtcgaaata
    10981 ccgattccat tatcagaaac aagtaaataa agattgcgat cggtcgccga gataagaaaa
    11041 tcaatttcac catcctcctc agtatacttg acggcattat cgaaaagaat ggtcatcagt
    11101 tgtttcagaa gaagctgatc tgtgacaatt gttcgatgga tacgattttc aaaacggaag
    11161 acacgattat tttccgaagc aatcatctcg tagtttgtga aagttgtatt aaaaaagcta
    11221 gttggaactt ctgcaagctc cggcttaatc ccatcatctc tccgagctaa gttcagcaag
    11281 cttgtcgtta aaaaacgcat atttcggact tcttccaaac tcgatgcaat gctttcgctc
    11341 acatccataa tggtagcttc tggcttacga aaaagggtct ctaagcgatt ttgcaaaact
    11401 gcgagtggag ttcgtaactc atgactggca ttttccacaa aagactgttg cttctgcata
    11461 ctctcaagca ggggcctaac actgacccta gctagataga gactggcaag taaagacaaa
    11521 atccagaaac tagccatcac gaccacaatc aattgctcat gcttttgact agcctgttcc
    11581 aactgactgg tattaatcaa gacagcagca tacttgatat tggttgaaac cgaactaata
    11641 ttggtctcca tcaaaatcac acgatagatt tcttcctgcc catagctatt aaaaacctga
    11701 atctggtaga tatgtcctag ttctttcttt tctaacttaa tcttatccaa gcccaaaaat
    11761 cgatttccag aaagaagttg agtaaagtct ttatcaaaga gaatgacttc cgtattggaa
    11821 ctgacattag gttttatttc tactttacta gcgtccgccc tagcattttc taaatcttta
    11881 atctcttctg ttgccctatt tatagccagc tgaataactg cttgaggatt ttcactcagt
    11941 ccatgaagct tatcgtccac cgaagtataa agactcgaat gcatgacttg taaaataatc
    12001 agagtcattg tagaaaaaat cagggtgaag acaccgaagt tgcggataaa ataactaaag
    12061 tcatccgcat accatgtttt tttaagttta ctgaacatct tttaaaagat acccaacact
    12121 acgcaaagtt tgcaaattct ctgcaaaagt ggttcccttt aatttcttac ggacttttga
    12181 aacatagact tcgacaaccg aaatcgttgt atcactatca aatccccata gacggtcaaa
    12241 aatctgcgtc ttaggcaaaa tcacattttg attttgaagg aaataaacta gtaaatcgaa
    12301 ctctttcccc agcaattcga caggagtatc ttcaacttta acggtattgg ttgataaatt
    12361 aaccacgata ttcccataag tcaaggtgtt ttcattaaac ttccctgaac gtttgagaag
    12421 ggcctgaatc cgcattttaa gttcttctag gtagaaaggt ttggtcagat aatcatccgc
    12481 tcccagttca aatccatgtc ccttgtcatc caaactttcc ttggcagtca taatcagaac
    12541 tggtgtcgta attccctttt cacgcaattc ttttaagact tggaaaccat ttttttctgg
    12601 caacatcaaa tccagcaaaa tcaagtcata gacaccactc tcagcttcgt agagaccttc
    12661 ttctccatca aatacctgca taacatccgc aaaatcgtct aaaaagtcaa atactgaatt
    12721 tgacagacct aggtcatcct caaccaataa gatttttatc atgagaaact cctccttatt
    12781 aaaactatta taccaaattt gccttaaaaa aaactcaact ctctgcattt tacatgagat
    12841 agctgagttt tctttttatt ttaggcttat ttatgcattt ccgtattgaa gaacaactgc
    12901 ttcgactgca gctttttcac ggctaatcaa gtcaacacgc gctgcaattt ccttgattcc
    12961 cataccgatg ttacggctaa gagcaaggtc agaaagttgc ggctcaaaga actccttgta
    13021 ttccgccaag cgttgctgag tcttaaatac atgagcagga aggataacaa agctatcaaa
    13081 gctcatatct cctccaaggg ctgccttaat ccaagcccag ttttcacgcg cccaagacca
    13141 agctgttttc tgagttgctt gatgagctag gaattggtaa taccaagcag acaagtcctg
    13201 tggtttgacc acaaatttgt ccttccaaga agtaatcaag ttttggatat tatccgcatc
    13261 tgtactgtat gcaagagctg ctgccaactg gcgtttaaag acagcatctg ttgcgtgagt
    13321 ataagtatca agataaagtg ctaacaagtc tttagtctca tgatgtttca tctcattaat
    13381 cagaacttgt gaacgaatag ctgctgggag tcctgcaaga ttctccttgt gtgttgcgaa
    13441 gatttggcta gcgacttgac tagcttctgc atcatttgag cgaatcatca tcgaaacagc
    13501 cagctgacga accaattcat cctcatctga ttctccgtct ttagcttcaa aaccaagacg
    13561 gtcatagtta tgacgagcca atttagcaac cagtcctttg aaggctgttt cagcatccgt
    13621 tccttcatca ataaagcgct caagggctga aatcacttga gaaacagctg aaaccaccag
    13681 ataagactct tccttagcaa gtttatcaag aactggaagc aagtctgcat aagcaatgtg
    13741 ccctgcctca gccaacaaac gacgttcttg aacaatttgc agtttgcttg tgttatcaag
    13801 tgtctctagc tcagcaagaa cagcttctaa caagtctcct tgatagtcgg taatatagtg
    13861 ggcagtattt tcagtgttga gacgaagagc tccttcattt tcagcaagaa gagctgcgta
    13921 gccagggatt tcgatacttt cagtttcgag tgtatcaggc aagcctttcc agttgctatt
    13981 gaggggcacc acccagagac ggttcttgtc ttcgttctca ccgatgaaga attgtttttg
    14041 tgaaatcttc aagacatcat tttcaacttt aacagtaaga actgggtaac caggctgttc
    14101 caaccaagaa tccatgaagg ctgcgacatc acgtcctgac gcttgaccaa gggcatccca
    14161 aaggtcacta ccaatggtgt tgctgtattg gtgtttttca aagtaggcgt gcaaaccttt
    14221 agcaaaatca gcatctccta gccaacggcg aagcatgtgc atgagacggc ttcctttggc
    14281 atagacgata gcgccgtcaa agagtgtatt gatttcatct ggatgtttaa cttcgacgtg
    14341 gacagactga acgccatcag tagcgtcacg ttcaagagca agaggtactc cacctgtttg
    14401 gaaatcttca aagatattcc agcttggttc gatggtatcc acacagacgt attccatcat
    14461 attagcgaaa ctttcattga gccaaaggtc atcccaccat ttcatagtca cgaggttccc
    14521 aaaccattgg tgagccaatt catgggccac aacaagggca acttgttgac ggctagcaaa
    14581 tgtagagttc tcatcgacaa ccaagtaaac ttcacggtag gtcacaagac cccagttttc
    14641 catagcacca gctgagaagt caggaagggc gatgtggaga gattgaggaa ttgggtactt
    14701 aactccatag taatcttcgt aaaactcgat agagcgaaca gcgatatcca gtgagaaatc
    14761 aagatttgaa agtggatgtg ctttggttga gtagacacct accagggtac catttttagt
    14821 tttagcggtc accccttgca aatcaccagc aacaaaggcc aacaagtaag aagacatgcg
    14881 aggtgttgtc tcaaacttcc agatacctgt ttccttacgg ttttcaacat cgatttctgg
    14941 catgtttgac aaggccaatt caccttctgc ttggtcaaag cgaagagaga ggtcaaaagt
    15001 tgctttggct tcaggctcat ccacacatgg gaaagcttcg cgcgcaaaat ggctctcgaa
    15061 ctgagtagac aagacctcct tcttgactcc atcaactgta taataagaag ggtaaatccc
    15121 tgtcatgttg tctgtaattt taccagaaaa ggcaagaacc aattcaactt gaccagcctc
    15181 agccaattcg atatgaaggg cttcattgtc atggtcaact gtaaatggac gagcttgacc
    15241 tgcaacttct acagaggtga tttccaagtc tttttggtgg agggagatgc ggtcactctg
    15301 tgcttgacca gtgatggtca ctttcccaga aaaagtcttg gtctcacgac tcaaatctaa
    15361 aaataaatca taatgttcag gaacaaattg cttaataaaa tgttcaactg cttgcatagt
    15421 tttctcctat tctaagttta agagctactg ctcttcttca aacaaactta ttatatcata
    15481 ttttgcttga gaaaaaagga ttggacagcg atttccaaaa ctttcttcct tctaaatagt
    15541 ctacagtggg tagaccttgc gaaattcttc taaaacaacc ttgctttcag gtgtaaaagt
    15601 cagccctact tcacccaaac agtctgtgaa aaagtcctca tgaacctggc gccaataggc
    15661 aagtgatttg tctccctcac cttccttaaa ggcatgttgc gcagaaactt gattgaagag
    15721 ttcaacagaa acctttgtaa tttcgacaat gcagacagac tgattttgac tatctaaaat
    15781 gacatcgaag gtccctactt ggggaagtgg ttcgtcttct agtacataga ggtcataggc
    15841 tgatgctgtt gctgtctttt ctcctttaaa caccaaatcc gctaaaaggt ctggttcaac
    15901 tccaaaagcc caagcatcga tttcatctcc gatcaaagga ttgatttgct tgtatttatt
    15961 ccacatttct tgcggtatca tgggtactcc tttgtaattt tttactttct tcttttatgt
    16021 gtttaagatg atctggatgg tcaatctcta aatcaaaaat ctctggaata gaactgtagt
    16081 ggataatgca cttgataccc aactgattca ttttttgtat gaaagaagta ttcagatagc
    16141 ctgctacagc aaaattaatc ttgttctttc ttgctttatc ctgcatatct cttagcatat
    16201 ctaacattat tggactttcc agatcatgcc attgactgtt tctcatagtc gcaaaaacaa
    16261 aggaagtcaa atcattcatt ccaactacaa tctttgaaat gcccgtttcc agtatactag
    16321 ataagtcaaa atacgctgac ggtaattcaa tcatcgttcc gactttccca gtaaagccat
    16381 actgacgcaa tactgtaata gcttgtttta attggtcggc atcattgaca aaaggaaaga
    16441 taacagatag attggggttg gtttgataaa cttctgtaac gacatgtgct tcagcctgaa
    16501 attcatccaa acacgccagt aaacgcctgg ttcctctata gccaaacaag ggatgccctt
    16561 cgtcaaaaaa ctctttagtc cccactaaac aattggcttc tgtattcgtt aattcagtaa
    16621 aacgatacca aacttcttca tctgagtaca gggagcagat agtctctaga taatctttta
    16681 caaattgctg acaacttgct aatatgatgt tttgattaag ctctctcaac aaatattccc
    16741 cacgaatcat gccgacgtgg tgaaatagtt gaggataaat tttttcaaga attttttcgc
    16801 cactaagggc aagttgattt ctcatagcca ttcacctcgt cttaaaagat acaatatcat
    16861 atataattat atcaaaattt cctctagttc aaaagcttca taaggttcag ataactcata
    16921 tcctaaaaat tctgctactt ttttggaagc ctcattatga gcatcccaaa gtggaaacat
    16981 atctctattt aaactctcta gaatcattgc agcaccaagc tttttagcaa atccatttcc
    17041 ttgttcgttt ggtctagttg caacttccac ttcaactgct ttacggtaaa ctaaccctga
    17101 ggaaatccca gcaatcagtt cattattttt aagaatcaca aagccaaatc caccttttaa
    17161 aacaaaatcc tgataggact caaaatcccc ctgtaaatcc tgtgaccatt cttccgtaga
    17221 aaagcagtta taaatatgat tatcaatagg cacaatattg taaccttcct ctaaatgagt
    17281 aactagatta tttaaaaatt caacttgaaa atttgcctta tctttaaaag aatagcgagt
    17341 aaaagaattt agccccactt ttcgatgcag aaaatcttgc caattagtat tttctgaaat
    17401 aataatctta taatctaaac catattttct aacaaaatct tcccaaaatc tggaatccaa
    17461 ctcccctgct aggtatagaa aattcccaac atcataaaag cttgttgtcc tatcattgtt
    17521 tcggtagaca gttccaattt gagatttaag accatagaga accatatttt tcttccatgt
    17581 tttaaatagt tccattatcc ctctacttca ccttccaatt catgtaagaa gtcttgtcca
    17641 gttctggaaa tcctaataat tcagacttaa ccttcaagac taatggcgat gcattttctt
    17701 ctgtaatctc ttgaatatcc atccaaatat atccaagtga atcattcgca ccatcagaca
    17761 cagcttccga agtcgtaact tgaggtgcac tctcattcat ttcaacatca tacaaggcca
    17821 tgacatggtc aaccataaaa tttgttaact cttctctgac gaaaacatcg tagattcgag
    17881 gattagagta gcttctaaca gtaaatcccg tctcttccat aacttctcta gtcagcgttt
    17941 ccgtcagtcc ttcaccaagt tgctgactgc ctccaggtag atcataccga tgttgataag
    18001 ggcctctcgt tttttcaatg cagagtaact tcccattttc taagcaaaca gcgtagactc
    18061 caaagtgttt tttgatttcc atccaactcc tcctacttca aagaccagcc accatctatt
    18121 gtcaagattt gtccttgcat ggcgctcgct tttccacttg ctaaaaaaag actaagctct
    18181 gctatttcct ctggctcaat ccagcgcttg attggagttt cactagccac ccagtcagcc
    18241 aaaccacctg gttcaaaatc cgcagcggtc atagctgtct tgactgctcc tggagcgata
    18301 ccaaagacct gaatcccagc ttcagcatag tctagagcca actgcttggt gaagccagcc
    18361 aaggcatgct tggatgaagt ataggcgtga ccacctccac ctgctaggct agaagcaatg
    18421 gaacacatat tgatgatgat tcccttttta ttttccagca tttgtgtcaa ataataccga
    18481 gtcaactcta ctggaataat gtagttgatt tcaaaaatct cttgaatgtc ctgcgccgtt
    18541 tgttccaaca gtggtttgta atcatccaaa actccagcag tattacacaa aacatccacc
    18601 tgagggcacc agtcaaaaat aggttccaag tccaaggtca aatctctctg taaaaagtga
    18661 aaatcaccct ctaagagtgg cttttcacct tggtcaactc cataaacttg atagcccttc
    18721 tctaaaaaga ggcgagcttg agccaatccg atccctgaac tcactcctgt aatgagtaca
    18781 cgtttagtca tgcacttcta cccaatccgt tgccaaaaca tcacaaactg tcgggctcca
    18841 catggaaaaa ccttctcctt cgccagaaac gttgattagg aaataaggtg tcatttcaag
    18901 tgcaagccca ttttgctcga tggtatcaaa gagttggaca tagttttccg cacctcccca
    18961 accagttcgt acatattttc tcttagcctt taacccaggc aggatctctt caaatgtcat
    19021 gtttttctcc tttaattcta cattcttcat ttaattatag caaaaaaccg ctttatacgg
    19081 ctttttgaat gtgagttatt caaacctgct actacttacg gcaaattatt ccctgcagca
    19141 agataaattt cataccattc ttttcttgtt aagctaaagt ttgccgctcg gctaacttct
    19201 ctcaagtgct taggatttgt tgtacctacg actgcctgca tttttgctgg ataacgcaat
    19261 atccaagaaa tggcaatagt tgaagaggtt actccatatt taatagctaa acgatcaagt
    19321 acttgattta aagcttgaaa tttctcattt ccaacaaaat tccctttaaa atacccgaat
    19381 tgtaagacag accatgcttg aatgaccaca tcgtgtaatt ggcaatattc aaaaatgctg
    19441 ccatctcgca tagctgcttg actatcttcc atattaacat gaaaagctga ttcaaatcct
    19501 ggagtaaaag ccgcactcaa ttgtagctga ttaacagcta acggctgctt gacatctttt
    19561 ttaagcaact ccatcatcat aggattttga ttagaaactc caaaatctcg aactttacct
    19621 tgtttataaa ggagattaaa ggcttctgct acttggtcag attccatcaa agcatctggt
    19681 cgatgaagga gcaagctatc tagatgatca atcttcaatc tttgcaaaat accgtctact
    19741 gattttataa tatagtcctt agaaaaatca aaataggtaa attcttcaat gcgaatgcca
    19801 catttggact gaatccacat cttttctctt aaatctggac gattttttag gacaagacct
    19861 aacagttctt cacaacgacc acgaccataa atatcagcca agtcgaaggc attgattcca
    19921 acagaaagtg ctgtttctac aagctcttca acttctttta cagacttatc ttttattctc
    19981 atcattccga gaacaatttc tgataattct ttgtcatctt gaccaagagt tatgtatctc
    20041 atcaaatttt tctcctttaa tttctaacat tcttcccttc attataacaa aaaaccgctt
    20101 tgcaacggct ttttgactat acttcactcc attttatctt cttaaaccca cggaacaaga
    20161 caaagattcc aataaagagg acagctaaag gaataacttt tgtaaggaaa acatttgaaa
    20221 ttcccatcca ctcataataa cggagcagag aacccaccac aagatgggca ataatcatac
    20281 tgacaaatgg acgaaagacc gcttctttcc aattccaaat accgataact agcgaaatcg
    20341 taaagacaga caaactatcc cagggagccg gaatataaaa ggctccttct tgtatgaagc
    20401 ttgccattcc tacatatcct aaaacaacta gaagaactat agtcccaaca acaatgtaag
    20461 tgccaatttt cattttagga gaatcttgga ctaaacttct tcgtaaaatt gtggccacaa
    20521 gtccaaatcc aatcagaaaa ataagaagtt gccctaaaaa tgtgagcaaa ttgactgtta
    20581 agagaggacc tttagaaaaa tcacttagta gttgataata acgtaataca gccaggacaa
    20641 gaattggcgt caaaagggac tctttgatag aactgcgagg tgctcccttg agaatctctt
    20701 tcattatttt tttaggattc ttacctagat aatcctctgc actcatgcca tctcgttctg
    20761 cttctgagaa atctagcatc atcaaataga tctgctctct gagatagtct tcatcataga
    20821 gaaatccagc aagattaaaa ctttcccaca actcctcaaa atacttttga ttctcctcag
    20881 aaaactcatg tagcaaagcg cttgtttctt cgtaatactt cattttcttc atggtttaac
    20941 ccccattctt aatcccttct actttttgac tcaaatcgtc ccattgctgc caaaagactg
    21001 agacacgctc ttctccttct ttcgttaatg aaaaatactt ccgatctgga ccatctggcg
    21061 acgggcgcat gtcgcctctt atccattgat ttttttctaa cttttgcaac aaaggataaa
    21121 tagttcctgg aacgatagta tcaaatccag cctctcgcaa agtctgaacc aactcataac
    21181 cataccgctc tttttgacca atcatatcca agacacaacc ttcaagaaca ccttttaata
    21241 gctgagtttc tttcatcact tctcccttct aatctatttt gtaataccta ctagtaactt
    21301 cacctatagt atattacttc tacactagtt tgtaaagcat aatagttaat actcttcgaa
    21361 aatctcttca aaccacgtca gcgtcgccct accgtatgta tggttactga cttcgtcagt
    21421 ttcatctaca acctcaaaac agtgttttga gctgacttcg tcagtttcat ctacaacctc
    21481 aaaacagtgt tttgagctga cttcgtcagt ttcatctaca acctcaaaaa catgttttga
    21541 gctgacttcg tcagttctat ctacaacctc aaaacagtgt tttgagcaac ctgcggctag
    21601 cttcctagtt tgctctttga ttttcattga gtataaataa aaaaacagaa ctagtctgaa
    21661 ctagtcctgt ctacttttac ccaatcacac ttccatttgg tacagctgga tcaactgtga
    21721 gaagggttaa tttgccatca tattcagctg atagaatcat accctggctg acatattttt
    21781 tcatcatttt acgtggtttg aggttagcaa cgatttgaac tttcttgccg accaattctt
    21841 gttcatttgg atagtatttt gcaattcctg aaagaatctg acgatcttct ccatcaccag
    21901 catccaagcg gaattgaagc aacttatctg aaccttctac tttagacact tctttgactt
    21961 ctgcgacacg gatttcaacc ttgtcaaagt cttcaaactt gatttcatcc ttgtttagtt
    22021 tgagctcaac ttcgtccgga ttccattctt tttcgactgc tggtttattg ccttccattt
    22081 gttccttgat ataggcgatt tcttcttcca tatttagacg tggaaagata ggtgttcctt
    22141 tggcaactac agtcacatct gctgggaagt cagccaaact caagttttca agactagaaa
    22201 cttcttccaa accaagttga gtcaaaactg cacgactagt ttccatcata aatggttcaa
    22261 tcaagtgagc aactacacga atgctggctg ccaagtggct catgacactt gccaattggt
    22321 cacgaagagc ttcatccttg gccaagaccc atggtgcggt ctcatcgatg tatttattgg
    22381 tacgagagat cagagtccag actgcttcaa gcgcacgtgg atagtcaact gcttccatgt
    22441 gtgtatggaa gtctgcgatt gattgttctg caacctcagc aagaacatga tcaaattcag
    22501 tcacaccttc tacataggca gggatttgtc catcaaagta cttattaatc atggaaaccg
    22561 tacggttaag gaggttccca aggtcattag ccaattcata gttgatacgg ccgacatagt
    22621 cttcaggagt aaaggttccg tctgaaccaa ctggaaggtt acgcatgagg tagtaacgaa
    22681 gtggatctag tccataacgc tctaccaaca tttcagggta aacgacattc ccttttgact
    22741 tagacatttt tccgtctttc atgacaaacc aaccatgggc aatcaaacga tcaggtaatt
    22801 taacatccaa catcataaga aggattggcc agtagataga gtggaagcga aggatatctt
    22861 ttcctaccat atggaagact gttccattcc agaacttgtc aaagttacca tgttcgtctt
    22921 gagcgtagcc aagagctgtc gcatagttaa gaagggcatc aatccaaacg tagacaacgt
    22981 gttttggatt tgatgggaca ggcactcccc atgtaaaggt tgtacgagat accgccaaat
    23041 cttccaagcc tggctcgatg aagttgcgta gcatttcatt aaggcgacca tctggcgtga
    23101 taaattcagg atgagctttg aaaaattcga ccaaacggtc ttggtatttg ctaaggcgaa
    23161 ggaagtatga ttcttcagaa acccattcaa cctcatgacc tgatggagca ataccaccag
    23221 tcacatttcc agcttcatca cggaaaactt ctgccagctg gctttctgta aagaattctt
    23281 cgtctgatac tgaataccaa ccagagtatt cacccaagta gatatcatct tgagcaagta
    23341 agcgttcaaa gacctgtgcg acaacttttt catggtagtc atcggttgta cggataaatt
    23401 tatcgtatga gatatctagt aattgccaga gttctttaac tccaaccgcc attccatcaa
    23461 cataggcttg aggtgtaata ccagcttctt ccgctttctg ctggattttc tgaccatgtt
    23521 catcaagacc tgtcagataa aatacatcgt agcccatcag gcgtttgtaa cgtgctagga
    23581 catcacatgc gatagttgtg taggcagaac cgatatgaag tttcccagat ggatagtaaa
    23641 tcggcgttgt aatataaaaa tttttttcag acataatttt tcctttccag gcaaatgaaa
    23701 cctgtttttc taacacttca ttatatcaca tttttaatga atttcgatag ggaaatccat
    23761 acaaaaacaa gatagacgag tgtccatctt gttgatctca ttcataacga agggcttcaa
    23821 ttggatcaag tttcgatgcc ttgttggctg gcaagactcc aaaaatcata ccaacactag
    23881 ccgaaactgc aagactaaat agggcaactg ggattgatac tccaacttct ataccttcta
    23941 ttaaaccttg cagtaacaaa cctgctaagg cagttaaacc acttgcaatt gtcaagccaa
    24001 ttaagccacc taacaaggtc aaaatcatgg attcaatcaa aaactgaatt aaaatattgg
    24061 cacgtgttgc acccaaagct ttacgaagac caatctcacg agtgcgctct gtcaccgaaa
    24121 ccagcatgat gttcatgaca ccagttcctc caacaaagag agaaatccct gcgatggaac
    24181 taataatcgt cgtcataaaa ctaaacgatt gttgaatttc tgcaaataca acggactcat
    24241 ctgccacctg gtattctccc tgttgtaagc ctgcaagctc tgtcattttt cgtgccagtt
    24301 ctggacccag agttggggtt aaactggtat cattcactcg aaagacaata ctagctattt
    24361 catctatatt aaaattcgca gcaagggaga tattggtagt aataggcaag ccaccaaacc
    24421 catatatttt tgacttttta gcctccggac tagtataaac cccaatgacc cggtaactaa
    24481 atccattgac ttctacaacc ttgttaatag cctcttgagg agattcaaat aaactaatgg
    24541 acaattcctc atctagcaaa ataacacttg caaactcttt gaaatcttgc tctctcagac
    24601 tacgacctgc aataatttca ttcttaacag cgtccatgta agttctgttt ccacctgtca
    24661 aattagcatt ctcaaccttt ttatcttgat aggtcaagat ggcattcgtt gaattggtta
    24721 catagtaact atccactccc ttcagtttag ctgcctcttg aacccaggat tcttgcggtt
    24781 ttggcggttc aacaggaact tcctcttcct ttccagaaac cgtaaaagct gattgtttct
    24841 gagtaaaaga cccatcttta ctttttttag gagagaaaaa gacgctaata tttttctgag
    24901 atttagtcat atctttattg acttgacgag atagggaatc acccaaagcc ataatcacaa
    24961 caactgatga aacaccgata ataatcccaa tcatagtaag caaagaacgc atcttgtgag
    25021 ccatgataga tgaaaaggca aatttcagat tctgcatctt agttttcctc ctttcctaac
    25081 tgagcactgt cagacgaaat gaccccatcc cgaatgacaa tctgacgttt ggcataggca
    25141 gcaatctcag gctcatgcgt taccatgata atggtttttc cttctttatt caaatcaacc
    25201 aataattgca taatttggtt acctgttttg gtatccaagg ctcctgtcgg ttcatccgct
    25261 aggataatag aaggattgtt taccaaggca cgcgcaatgg ctacacgttg cttttgacca
    25321 ccagataatt ctgaaggtaa atggtgacta cgttctgtca attcaacctt gtctaaatat
    25381 tcctcagcca acttgcgacg ttttgaagac gaaactcctg cgtaaatcaa gggcaattct
    25441 acattttgca gagcattgag cttcgataga agaaagaact gctgaaagac aaaaccgatt
    25501 tgttggttac ggaccttagc tagttgtttt tcaccaagcc cagccacttc ttgaccttca
    25561 agataatatt ctccactggt tggtgtatcc aacatgccaa tcgtattcat cagagtggac
    25621 ttaccagacc cagatggtcc catgatggct acaaattcac cctcattcac ttctagattg
    25681 atatttttga gaacctgcag ttcttggtca ccattacggt aacttctgaa gatatttttt
    25741 agactaatta gttgcttcat cagccttcac ctcttttcct tcttccaagg aagatgttgg
    25801 attactgatg accttagcac cgttcgttaa accagaagtg atttcttgat tttctgcgtc
    25861 agcatttccc aatgaaacct caactttttt agccttttgt tgttcatcca caatccagac
    25921 ataattttta ctatcatcca ttactagact gctaacagga ataagaatag ccttagtttt
    25981 gcttttaacc tcaatgttga cagaaaaacc ttgtttcaaa tcaccaacct cgcctgtcac
    26041 atcaatagta taagggtatt tagaacctgt attattcccg gctgctggac tagctgcttc
    26101 accattgttt ttaggatagt cagaaatata gcttaatttc ccagtccatt ttttatcagg
    26161 atacacttta gaagtaaagc ttacttcttg acctacagaa aggttggcta gattgtactc
    26221 agacaattct cccttgactt gtaaattttc attgctgaca atatgaacca taacttgact
    26281 cgcccctgtt ggagatttag aaacattgct attgacttcg actacagttc cctctagggt
    26341 actgagaaca gttgttgcat ccaattgact ttgagccttg cttaattgcg ctgcagcatc
    26401 tgcacgcgca tcacgggcat cacccaattg agcatcaata gaagcaacag aatttccagc
    26461 cactggagtt gggctttgca ccgttgcatc ttctcctcct actggcgctg gtaactgtgg
    26521 agcctgagct gaagcggctt catttcgtgc ttgattgagt tcattgatat gacgatctgc
    26581 cttagctact gctcgactag ctgaatcata ggccgcctgc gcttctgaac tactgtactt
    26641 gactaaagcc tgcccttcgc tgaccttatc gcccacagaa acaaggattt catctaaatc
    26701 acccttacta gcatcaaaat aaacatattg ttcatttttt gctgttactg tccctgacaa
    26761 taaaacagag gatgccacgc ttccttcctt ggcaacaaca agatgagtag gctcatcttt
    26821 tacagcagtc tgagaaggtt gtctaaaaag taaaatcccc ccggcaccca atacaactac
    26881 actcgcagca ccgattgctg catacagttg ccacttttta gctttaccat tctttttctt
    26941 cataatgaaa ctccttttct tttttacaat actttgctat tataccaaat ttccctccag
    27001 caaacaatgc agttcagatg gaaataatgg cagttcagga ttaaacaatc gttcggaatt
    27061 ttgcttttct attgtactag atatataata cactatcttg acttatttgg caagcttttt
    27121 tgcaattttt tgtgcgtagc agatttttgc aatcaaatca aaaaaagaat aaaatataac
    27181 tatcaaaaaa gacactctac tatttaaaag attacaaagg agttttcaat gagagaatat
    27241 gatatcattg ctatcggtgg aggtagcgga ggaatcgcta ccatgaaccg tgctggtgaa
    27301 catggagcca aagcagccgt tattgaggaa aagaaattag gtggaacctg tgtcaacgtc
    27361 ggttgtgttc ctaaaaaaat catgtggtac ggggcgcaaa tcgctgagac tttccatcaa
    27421 tttggagaag actacggctt taagactact gatcttaact ttgactttgc aaccctacgt
    27481 cgcaatcgtg aagcctacat tgatcgcgct cgttcttctt atgatggtag ttttaaacgc
    27541 aacggtgtag acttgattga aggtcatgct gaatttgtag attctcatac tgtaagcgta
    27601 aatggtgaac tgattcgtgc taaacatatc gtgattgcta caggtgccca tccaagtatt
    27661 cctaatattc ctggtgctga gctaggtggc tcttctgatg atgtatttgc ctgggaagaa
    27721 cttccagagt caattgccat tctaggcgct ggttatatcg ccgttgaatt agctggcgta
    27781 ctccacactt ttggtgtcaa gacagatctc tttgttcgcc gcgatcgtcc tttacgtggt
    27841 tttgattcct acatcgttga aggtttggtc aaggaaatgg aaagaacaaa cttaccactt
    27901 cacactcaca aagtccctgt caagttagaa aaaactactg acggcattac cattcatttc
    27961 gaagatggta ctagtcacac agctagccaa gttatctggg ctacaggtcg ccgtccaaac
    28021 gttaagggct tgcaacttga aaaagctgga gtgactctga acgaacgtgg ctttatccaa
    28081 gtggatgaat accaaaatac tgttgttgag ggaatctatg ctctaggtga tgtaacgggc
    28141 gagaaagaac tgactccagt tgcaatcaag gccggacgta ccctatctga acgtctcttt
    28201 aacggaaaaa ctactgcaaa aatggattac tcaactattc caactgttgt cttttcacac
    28261 cctgctatcg gaactgttgg tttgacagaa gagcaagcta ttaaagaata cggtcaagac
    28321 caaatcaagg tttataaatc aagctttgca tctatgtact ctgcttgcac tcgcaaccgt
    28381 caagaatccc gtttcaaact cataacagct ggttcagaag aaaaagttgt cggacttcat
    28441 ggaattggct acggcgttga tgaaatgatt cagggatttg ccgttgctat caaaatggga
    28501 gcaaccaagg ctgactttga tgcaactgtg gcaattcacc caactgcatc tgaagaattt
    28561 gtaaccatgc gttaatcgaa acaaaagaag ctgatataaa tatgtctgct tcttttt
//
LOCUS       DAVBIC010000028        28581 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.028, whole genome shotgun sequence.
ACCESSION   DAVBIC010000028 DAVBIC010000000
VERSION     DAVBIC010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 28581)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28581)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28581
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.028"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            complement(<1..204)
                     /locus_tag="VQ664_001179"
     CDS             complement(<1..204)
                     /locus_tag="VQ664_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HET2789345.1"
                     /translation="MYEESKQLTNAQFKRLVGVQRTTFKEMLAVLKTAYQLKHAKGGR
                     KPKLSLEDLLMGTLQYVREYRTYE"
     gene            550..1503
                     /locus_tag="VQ664_001180"
     CDS             550..1503
                     /locus_tag="VQ664_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET2789346.1"
                     /translation="MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFKEEEITILEMGSGMGILGATFLISLDKKVDYLGMEVDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGL
                     KYLKSDGYAIFLAPSDLLTSPQSDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKSEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            1554..2744
                     /locus_tag="VQ664_001181"
     CDS             1554..2744
                     /locus_tag="VQ664_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HET2789347.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHTQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYLAVLNGTDAIVFTAGVGE
                     NAENFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            2893..3264
                     /gene="rnpA"
                     /locus_tag="VQ664_001182"
     CDS             2893..3264
                     /gene="rnpA"
                     /locus_tag="VQ664_001182"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HET2789348.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYREGNGSEKETKVD"
     gene            3239..4063
                     /locus_tag="VQ664_001183"
     CDS             3239..4063
                     /locus_tag="VQ664_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HET2789349.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYF
                     FAKIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            4082..5068
                     /locus_tag="VQ664_001184"
     CDS             4082..5068
                     /locus_tag="VQ664_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HET2789350.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVDAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QTENQDLKEMGLKVEQSYDIAQVATDVTAYVQAIVDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNRYSKTFYVTINVNDYVEHRAEVLQTYAQKL
                     AIRVLEEGRSHQTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            5119..5742
                     /locus_tag="VQ664_001185"
     CDS             5119..5742
                     /locus_tag="VQ664_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P"
                     /protein_id="HET2789351.1"
                     /translation="MLNKIRDYLDFAGLQYRNPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPGWQLQQTSQWMNQAQRLRPHFWVYLQRDEQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLGKQAKVLDIPTVKGIYYLTYSNGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            5873..7330
                     /locus_tag="VQ664_001186"
     CDS             5873..7330
                     /locus_tag="VQ664_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HET2789352.1"
                     /translation="MEVVSSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIAAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFTFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            7353..7634
                     /locus_tag="VQ664_001187"
     CDS             7353..7634
                     /locus_tag="VQ664_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET2789353.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            7711..8196
                     /locus_tag="VQ664_001188"
     CDS             7711..8196
                     /locus_tag="VQ664_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET2789354.1"
                     /translation="MNLKQALIDNDSIRLGLEANNWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            8213..8878
                     /locus_tag="VQ664_001189"
     CDS             8213..8878
                     /locus_tag="VQ664_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HET2789355.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAADPAGAARAFKDEIKR
                     IWG"
     gene            8882..9745
                     /locus_tag="VQ664_001190"
     CDS             8882..9745
                     /locus_tag="VQ664_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HET2789356.1"
                     /translation="MVRPIGIYEKATPTHFTWLERLNFAKELGFDFVEMSIDERDERL
                     ARLDWSKEERLEVVKEIYETGVRIPSICFSGHRRYPLGSKDPVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIN
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SRGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAIQEAQAF
                     LYPLIKKAGLM"
     gene            9747..10451
                     /locus_tag="VQ664_001191"
     CDS             9747..10451
                     /locus_tag="VQ664_001191"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HET2789357.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKAWSEIGSVVHTHSTE
                     AVAWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVGPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            10630..12303
                     /locus_tag="VQ664_001192"
     CDS             10630..12303
                     /locus_tag="VQ664_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HET2789358.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALGDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVILQVSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQVLPYLLLSCHNVEQYQERHQDIEKEFSLIRKRIEYQVSKKLGERLF
                     QKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKALLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIAYLTIHIGGFLKYTPSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNKSKSFSENLSSLISSYIVDSKLASKFQEEVQTLINQEIVVQAFLEDI"
     gene            12415..13506
                     /gene="ulaG"
                     /locus_tag="VQ664_001193"
     CDS             12415..13506
                     /gene="ulaG"
                     /locus_tag="VQ664_001193"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HET2789359.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            13620..15596
                     /gene="tkt"
                     /locus_tag="VQ664_001194"
     CDS             13620..15596
                     /gene="tkt"
                     /locus_tag="VQ664_001194"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HET2789360.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVTDYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDANRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKEL
                     ASQGEKIRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKVVRNLK"
     gene            15713..16012
                     /gene="yajC"
                     /locus_tag="VQ664_001195"
     CDS             15713..16012
                     /gene="yajC"
                     /locus_tag="VQ664_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HET2789361.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVEGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            16059..16487
                     /locus_tag="VQ664_001196"
     CDS             16059..16487
                     /locus_tag="VQ664_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HET2789362.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQEYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNISDLRQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            16489..16899
                     /locus_tag="VQ664_001197"
     CDS             16489..16899
                     /locus_tag="VQ664_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789363.1"
                     /translation="MENLTNFYEKYRVYLTRPRLELLAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            17199..19850
                     /gene="adhE"
                     /locus_tag="VQ664_001198"
                     /gene_synonym="adhC"
     CDS             17199..19850
                     /gene="adhE"
                     /locus_tag="VQ664_001198"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HET2789364.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWITEPSMEATSALMNHEGIATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTIHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
     gene            complement(20835..21143)
                     /locus_tag="VQ664_001199"
     CDS             complement(20835..21143)
                     /locus_tag="VQ664_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET2789365.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEAHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
     gene            complement(21140..21448)
                     /locus_tag="VQ664_001200"
     CDS             complement(21140..21448)
                     /locus_tag="VQ664_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET2789366.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNIPVDTIDMRDYGMMNGAKVLEQALAWIGEIR
                     "
     gene            complement(21453..22748)
                     /locus_tag="VQ664_001201"
     CDS             complement(21453..22748)
                     /locus_tag="VQ664_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET2789367.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTKFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPSAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVSRSFSVLLPVMTVISLFGIVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            complement(22766..24175)
                     /locus_tag="VQ664_001202"
     CDS             complement(22766..24175)
                     /locus_tag="VQ664_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HET2789368.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENVMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTAFTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQVIYNLNLASAKVIQLYRSLGLDG
                     KIGIILNLTPAYPRSNSPEDLEASRFTEDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWPERRM
                     NPYRGWEIFPKAIYDIAMIVKEEYGNIPWFISENGMGVENEARFIDENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSLCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKSS
                     GRWYRKVSDNNGFEVEIEE"
     gene            24333..25061
                     /locus_tag="VQ664_001203"
     CDS             24333..25061
                     /locus_tag="VQ664_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET2789369.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            25521..25715
                     /locus_tag="VQ664_001204"
     CDS             25521..25715
                     /locus_tag="VQ664_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2789370.1"
                     /translation="MKGKEYENRTVSFAISSKGEKMKVENISYRVDHRILFDNISFDT
                     SSSDVTLITGKNGTGKSTLL"
     gene            complement(26081..27391)
                     /locus_tag="VQ664_001205"
     CDS             complement(26081..27391)
                     /locus_tag="VQ664_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HET2789371.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNFAITNGTLDVLAQHILYRTRTYPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGRTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYRKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTSIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            27628..28500
                     /locus_tag="VQ664_001206"
     CDS             27628..28500
                     /locus_tag="VQ664_001206"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HET2789372.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAILLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
BASE COUNT         8952 a         5089 c         5953 g         8587 t
ORIGIN      
        1 ttcataagtg cggtattctc gcacatattg aagagtgccc ataagaaggt cttctaggct
       61 taatttaggt tttcgtccac cttttgcgtg tttaagttga taagctgttt ttaatacagc
      121 taacatctct ttaaaagtcg tgcgctgaac accaacaaga cgcttaaatt gtgcattggt
      181 tagttgttta ctttcttcat aaattttatt gtatcatatt tttgtttcac aggaagtcta
      241 ataaataaaa attctttaaa attttgttgg gaaaatggga aaagatataa atggaaactt
      301 agtataacac ttggaaaact ctgtaaaaat agtaagtcaa ttcatgtccc gttttttctc
      361 tagggaagtt gggcggctat atttatatga ccatttgtcg taataaacat ccctaccaag
      421 ggtcaataga aataaattca acgaaacttt tgctgtcaga tttagatgcc caatttgtca
      481 tttatactct ttcatatagg actttctata aggatggaaa aaagaaggga aatttgataa
      541 gataggaata tggattttga aaaaattgaa caagcttata cctatttact agagaatgtc
      601 caagtcatcc aaagtgattt ggcgaccaac ttttatgacg ccttggtgga gcaaaacagc
      661 atctatctgg atggtgaaac tgagctaaac caggtcaaag acaacaatca ggcccttaag
      721 cgtttagcac tacgcaaaga agaatggctc aagacctacc agtttctctt gatgaaggct
      781 gggcaaacag aacccttgca ggccaatcac cagtttacac cggatgctat tgctttgctt
      841 ttggtgttta ttgtggaaga gttgtttaaa gaggaggaaa ttactatcct cgaaatgggt
      901 tctgggatgg gaattctagg cgctactttc ttgatctcgc ttgataaaaa ggtggattac
      961 ttgggaatgg aagtggatga tttgctgatt gatctggcag ctagcatggc agatgtaatt
     1021 ggtttgcagg ctggctttgt ccaaggagat gccgttcgtc cacaaatgct caaagaaagc
     1081 gatgtggtca tcagtgactt gcctgttggc tattatcctg atgatgccgt tgcgtcgcgc
     1141 catcaagttg cttctagcca agaacatact tacgcccatc acttgctcat ggaacaaggg
     1201 cttaagtacc tcaagtcaga cggatacgct atttttctag ctccgagtga tttgttgacc
     1261 agtcctcaaa gtgatttgtt aaaagaatgg ctgaaagaag aggcgagtct ggttgctatg
     1321 attagtctgc ctgaaaatct ctttgctaat gctaaacaat ctaagactat ttttatccta
     1381 cagaagaaaa gtgaaatagc agtggagcct tttgtttatc cacttgctag cttgcaagat
     1441 gcaagtgttt taatgaaatt taaagaaaat tttcaaaaat ggactcaagg tactgaaata
     1501 taaaatagat tttgttataa tagttgaaaa cgcttaaaaa ggggtatcat gttatgacaa
     1561 aaacaattgc aatcaatgca ggaagttcaa gtttgaaatg gcaattatac ttaatgccag
     1621 aggaaaaagt gttagccaaa ggtttgattg aacgtatcgg tttgaaagat tcaatttcaa
     1681 ctgtaaaatt tgacggccgt tctgaacaac aaattttgga tatcgaaaat catacacaag
     1741 ctgttaaaat tttattggat gacttgattc gtttcgatat tatcaaggct tatgacgaga
     1801 ttacaggtgt tggccaccgt gttgtagcag gtggagaata tttcaaagaa tcaacagttg
     1861 ttgagggaga tgttttagaa aaagttgaag agttgagttt gttggctcct ctacacaacc
     1921 cggccaatgc agcaggtgtt cgtgctttca aggaattgtt gccagacatt accagtgtag
     1981 ttgtttttga tacttccttc cacacaagta tgccagagaa agcttatcgc taccctctac
     2041 caacaaaata ttacacagaa aacaaggttc gtaaatacgg tgctcatggt acaagtcacc
     2101 agtttgtagc aggagaagct gcaaaactct tgggacgtcc attagaagac ttgaagttaa
     2161 ttacctgtca tattggtaac ggaggctcaa ttacagctgt gaaagccggc aaatctgtag
     2221 acacttctat ggggttcact cctcttggtg gtattatgat gggaacgcgt acaggggata
     2281 ttgatccagc tatcattcct tatttaatgc aatatacaga ggattttaac acaccagaag
     2341 atatcagtcg tgttcttaac cgtgaatcag gtcttttggg agtttctgct aattctagcg
     2401 atatgcgcga tatagaagca gctgtagcag aagggaatca cgaggctagc ttggcttatg
     2461 aaatgtatgt tgaccgtatc caaaaacata tcggtcagta ccttgcagtg ctaaatggaa
     2521 cagatgccat tgttttcaca gcaggtgtcg gtgaaaatgc agagaatttc cgtcgtgatg
     2581 taatctcagg gatttcgtgg tttggttgtg atgttgatga tgaaaagaat gtctttggcg
     2641 ttacaggaga catctcaaca gaggcagcta aaatccgtgt cttggttatt ccaacagatg
     2701 aagaattagt cattgcccgt gacgttgaac gcttgaaaaa ataagtgaaa ctaaaaaaat
     2761 attcaataca aggagttggg aaagttattt ttccagcttc tttttctgat gaaattgtcc
     2821 aaaaccttgc tatgattggc ttttttgaaa aatatggtat aatagtagta atttaataga
     2881 tggagttgag ttttgaagaa aaactttcgt gtaaaaagag agaaagattt taaggcgatt
     2941 ttcaaggagg ggacaagttt tgctaatcgc aaatttgtgg tctaccaatt agaaaaccag
     3001 aaaaaccatt ttcgagtagg tctatcagtt agcaaaaaac tggggaatgc cgtcactaga
     3061 aatcaaatta agcgacggat tcggcatatt atccagaatg caaaagggag tctggtagaa
     3121 gatgtcgact ttgttgtcat tgctcgaaaa ggagtcgaaa ccttgggata cgcagagatg
     3181 gagaaaaatc tactccatgt attaaaatta tcaaagattt accgggaagg aaatgggagt
     3241 gaaaaagaaa ctaaagttga ctagtttgct aggactgtct ctgttaatca tgacagcctg
     3301 tgcgactaat ggggtaacta gcgatattac agccgaatcg gctgattttt ggagtaaatt
     3361 ggtttacttc tttgcgaaaa tcattcgctt tttatcgttt gatattagta tcggagtggg
     3421 gattattctc tttacggtct tgattcgtac agtcctcttg ccagtctttc aggtgcaaat
     3481 ggtggcttct aggaaaatgc aggaagctca gccacgcatt aaggcgcttc gagaacaata
     3541 tccaggtcga gatatggaaa gcagaaccaa actagagcag gaaatgcgta aagtatttaa
     3601 agaaatgggt gtcagacagt cagattctct ttggccgatt ttgattcaga tgccggttat
     3661 tttggccttg ttccaagccc tatcaagagt tgacttttta aagacaggtc atttcttatg
     3721 gattaacctt ggtagtgtgg atacaaccct tgttcttccg attttagcag cagtattcac
     3781 ctttttaagt acttggttgt ccaacaaagc tttgtctgag cgaaatggcg ctacgactgc
     3841 gatgatgtat gggattccag tcttgatttt tatctttgca gtttatgcgc caggtggagt
     3901 cgccctatac tggacagtgt ctaatgctta tcaagtcttg caaacctatt tcttgaataa
     3961 tccattcaag attatcgcag agcgcgaggc cgtagtacag gcacaaaaag atttggaaaa
     4021 tagaaaaaga aaagccaaga aaaaggctca gaaaacgaaa taaataagga ggaatctggt
     4081 aatggtagta tttacaggtt caactgttga agaagcaatc cagaaaggat tgaaagaatt
     4141 agatattcca agaatgaagg ctcatatcaa agtcatttct agggagaaaa aaggctttct
     4201 tggtctattt ggtaaaaaac cagcccaagt ggatattgaa gcgattagtg aaacgactgt
     4261 tgtcaaagca aatcaacagg tagtaaaagg cgttccgaaa aaaatcaatg atttgaacga
     4321 gcctgtgaag acggttagtg aagaaaccgt tgaccttggt catgtggttg atgctattaa
     4381 aaaaatagag gaagaaggtc aaggtatttc tgatgaagtc aaggctgaaa tcttaaaaca
     4441 tgaaagacat gccagcacta tcttagaaga aactggtcac attgagattt taaatgaact
     4501 tcaaatcgag gaagcgatga gggaagaagc aggcgctgat gaccttgaaa ctgagcaaga
     4561 tcaaactgaa aatcaagact tgaaagagat gggcttgaag gtcgagcaaa gttatgatat
     4621 tgcccaggtg gctacggatg tgactgccta tgttcaagcg attgtggatg acatggatgt
     4681 tgaagctaca ctttcaaatg attataaccg tcgtagcatc aatctacaaa ttgacaccaa
     4741 cgaaccaggt cgtattatcg gctaccatgg taaagtcttg aaggccttgc aactgttggc
     4801 tcaaaattat ctttacaacc gctattccaa aaccttctac gttacaatca atgtcaatga
     4861 ttatgtcgaa caccgtgcag aagtcttgca gacctatgcg caaaaattgg cgattcgtgt
     4921 tttagaagaa ggacgtagtc atcaaacaga tccaatgtcg aatagtgaac gcaagattat
     4981 ccaccgtatt atttcacgta tggatggcgt gaccagttac tctgaaggtg atgagccaaa
     5041 tcgctatgtc gttgtagata cagaataagt aaaatcaggg ttgacctgat tttttgctag
     5101 ctagaggagg ttaaactaat gttgaataag ataagagact atttagactt tgctggtttg
     5161 cagtaccgta atcctgataa agcgggagca gagcgagaga agatgctggc attccgccac
     5221 aaaggacaag aggcccgaaa ggcttttaca gaactggcca aagcctttca agcaagccat
     5281 ccaggatggc aactccaaca gactagtcag tggatgaatc aggcccagcg tttgagacca
     5341 catttttggg tttatctaca gagagacgaa caagtgacag aacctatgat ggccttacgt
     5401 ttgtatggga catctactga ctttggaatt tctttggaag tcagtttcat cgaacgtaag
     5461 aaggatgagc aaacactggg caagcaggcc aaagttttag acattccaac cgttaaaggg
     5521 atttattatc taacctactc taatggtcaa agtcaacggt gggaggcgaa tgaagaaaag
     5581 cgtcgtactt tacgcgagaa ggtgagaagt caagaagttc gaaaagtttt agtgaaggta
     5641 gatgttccta tgacagaaaa ttcgtctgaa gaagaaatcg tagaaggctt attgaagtct
     5701 tattctaaaa ttcttcccta ttatctagct acgagaaaat aagataattt gtaaaacatc
     5761 ataaatcata cagtccaaga gtgaacagtc cgctgtgtaa ttcttggtct ttttgtttgc
     5821 gctttcgcat tatataataa acttacaaaa acaattcaaa aggagaacaa ttatggaagt
     5881 cgtttcaagt gttctaaatt ggttttctag caatattttg cagaatcccg catttttcgt
     5941 aggtttattg gtgttgatag gatatgcact tttgaaaaaa cctgcccatg acgttttttc
     6001 agggtttgtt aaagcaacag tagggtatat gttgcttaac gtgggtgctg gtggtttggt
     6061 tacaaccttt cgtccaatct tagcagctct taactacaaa ttccaaattg gtgcagcggt
     6121 tatcgaccct tactttggac ttgctgcagc aaacaacaaa attgcagcag agtttccaga
     6181 ttttgttgga actgcaacta cagctctatt gattggtttt ggaataaata tcttgctcgt
     6241 agctcttcga aagattacga aggtaagaac cctctttatt actggtcaca tcatggtaca
     6301 acaagctgca acagtatctc ttatggttct attcttagta ccacaattgc gcaatgctta
     6361 cggtacagca gcgattggta tcatctgtgg actttactgg gcagttagtt caaatatgac
     6421 tgttgaggca actcaacgct tgactggtgg tggcggattt gcgattggtc accaacagca
     6481 atttgcaatc tggtttgtag ataaagtagc aggacgcttt ggtaagaaag aagaaagttt
     6541 agacaatctt aaattaccta agttcctctc aatcttccac gatacagttg ttgcatctgc
     6601 taccttgatg ctcgtattct tcggagccat tcttttaatc ttgggtccag acattatgtc
     6661 taataaagaa gtcatcactt caggaactct attcaatcct gctaaacaag atttctttat
     6721 gtacattatc caaacagcct ttaccttctc agtttacttg ttcgttttga tgcaaggtgt
     6781 ccgaatgttc gtatctgagt tgacaaacgc cttccaaggt atttcaaaca aattgttgcc
     6841 aggttcattc ccagcggttg acgttgcagc ttcttatgga tttggttctc caaatgctgt
     6901 cttgtcagga tttacctttg gtttgattgg tcaattgatt acaattgttt tgctcatcgt
     6961 ctttaaaaat ccgattctta ttattacagg atttgtacca gtgttctttg acaatgcagc
     7021 cattgcggtc tacgctgata aacgcggcgg atggaaagcg gctgttatcc tttcctttat
     7081 atcaggtgtc cttcaagttg ctctaggagc tctttgtgtg gcccttctcg atttggcatc
     7141 ttatggtggc taccatggaa atatcgactt tgaattccca tggcttggat ttggatatat
     7201 cttcaaatac cttggtattg ttggttatgt acttgtgtgt ctcttcttgc ttgttattcc
     7261 tcaacttcaa tttgccaaag caaaagataa agagaaatat tacaacggtg aagttcaaga
     7321 agaagcttag tatctagaaa aggagaaata aaatggttaa agtattagca gcgtgcggaa
     7381 atggaatggg ttcatcaatg gttatcaaga tgaaggttga aaatgctctc cgtaagctta
     7441 atcaaacaga ttttacagtc aattcatgca gtgtcggtga agctaaaggt ttagcagtag
     7501 gatatgacat tgtaatcgct tctcttcatt tgattcaaga attggaaggg cgaactaatg
     7561 ggaagttaat tgggcttgat aacttgatgg atgataaaga aatcaccgaa aaactcagtc
     7621 aagcactaca gtaaaaggtt ggagggggct ggacagaaac tgagagttat cgtttctgtc
     7681 cagccccctc tttaaataaa ggaggcagat atgaatttaa aacaagcttt aattgacaat
     7741 gactcgatcc gactaggttt agaggctaac aattggaaag aagcagtcaa ggtagcagta
     7801 gatcccttga ttgaaagtgg ggcaattttg ccagagtatt acgatgctat cattgaatcg
     7861 actgaagagt atgggcctta ctatatcttg atgccaggta tggctatgcc ccacgctaga
     7921 cctgaagctg gtgtgcaaag tgatgccttt tcattgatta ccttacaaaa tcctgttgta
     7981 ttttcagatg ggaaagaggt atctgttttg ttggcactag cagcaacaag ttcaaaaatt
     8041 cacacaagtg tagccattcc acaaattatt gccctgtttg aattagaaga ttctattgca
     8101 cgtttacagg cttgccagac taaagaagat gtcttggcta tgattgaaga atctaaggat
     8161 agcccttatc tcgaaggatt ggatttggaa agttagaaag aggaataaag aaatgacaaa
     8221 aagaatacct aatttacaag ttgcattaga ccattcagac ttgcaaggag cgattaaagc
     8281 agctgtttct gttggtcagg aagtagatat tatcgaagct ggaactgttt gcttgcttca
     8341 agttggaagt gaactggctg aagtcttgcg tagccttttc ccagataaga ttattgtggc
     8401 agacacaaaa tgtgctgatg ctggtggaac agttgctaaa aataatgcgg ttcgtggagc
     8461 agactggatg acttgtatct gttgtgcaac catccctact atggaagcag ctctaaaggc
     8521 tatcaagact gaacgaggag aacgaggcga aatccagatc gagctttatg gcgattggac
     8581 ttttgaacaa gctcagcttt ggctagatgc aggtatctca caagctattt atcaccaatc
     8641 tcgtgatgct cttcttgctg gtgaaacttg gggtgaaaaa gaccttaata aggttaaaaa
     8701 actcattgac atgggcttcc gtgtatctgt aacaggtggt ctagatgtag atactctcaa
     8761 actctttgaa ggtgttgatg tctttacctt tatcgcaggt cgtggaatta cagaggctgc
     8821 ggatccagca ggagcagcgc gtgccttcaa ggatgaaatc aaacgaattt gggggtaaat
     8881 catggtacgt ccaattggaa tttatgaaaa ggcaacccca acacacttta cttggctaga
     8941 acgtttaaat tttgccaagg agttaggctt tgattttgtc gagatgtcta ttgacgaacg
     9001 tgacgagcgt ttagcaagac ttgactggag taaggaagaa cgcttggaag ttgtcaaaga
     9061 aatctatgaa actggtgttc gtattccttc tatctgtttt tcaggccatc gtcgctaccc
     9121 attgggttca aaagatccag ttctagagga aaaatctcta gaactcatga aaaaatgtat
     9181 cgaattagct caagacttgg gagttcgtac gattcaatta gctggttacg atgtttacta
     9241 tgaggaaaag tcaccccaga cacgccaacg ttttatcaaa aatttgagaa aagcctgtga
     9301 ctgggctgaa gaagctcagg tggtacttgc tattgaaatt atggatgatc ctttcatcaa
     9361 tagcatcgaa aaatatttgg ctatagaaaa agagattgac tctcccttcc tctttgtata
     9421 tccagatatt ggtaatgtgt ctgcatggca taatgatatc tatagtgagt tttatcttgg
     9481 tcatcatgcc atcgcagctc tccatctcaa ggatacttat gcagtgacag aaagttcaag
     9541 gggccagttc cgagatgtac cttttgggca aggttgtgtc aaatgggaag aagctttcga
     9601 tattttaaag gaaaccaatt ataatggacc tttcctaatc gaaatgtggt ctgaaaattg
     9661 tgaaacagta gaagaaacac gcgcagccat tcaagaggcg caagcttttc tctatccact
     9721 cattaagaaa gcaggtttga tgtaagatga atcaagtaat caatgctatg cgtaaacgag
     9781 tctgtgatgc caatcaatca ttgccaaaac atggacttgt caaatttacc tgggggaatg
     9841 tatctgaagt caatcgcgaa ctcggtgtca ttgttatcaa accatcaggc gtggattatg
     9901 acgaattgac acctgaaaac atggtagtga ctgatctaga tggtaagatc ctagaagggg
     9961 atttaagacc atcttccgac ctcccaactc atgtgcaatt atataaggct tggtcagaaa
    10021 ttggtagtgt ggttcacacc cattcgacag aagctgttgc ttgggctcag gcaggtcgtg
    10081 atattccttt ctacggaaca acccatgcag attatttcta cggttcaatc ccttgcgccc
    10141 gtagtttgac caaggacgaa gtagaagtgg cctatgaaaa agatactggc ctggttatcg
    10201 tagaagagtt tgaacatcgc ggacttaacc cggttgaagt accaggaatt gttgtacgca
    10261 atcacggtcc attcacctgg ggcaaaaatc cagagaatgc tgtttatcac tctgtcgtac
    10321 tagaggaagt atcaaagatg aatcgcttta cagaacaaat caatccaaga gttggacctg
    10381 ctccccagta catactagaa aaacactacc aacgtaaaca tggaccaaat gcttattatg
    10441 gtcaaaagta agaacgatga aggaggagaa aaagataaat ttagctcctc tttttacatt
    10501 tgatttttat tgagagtaaa gttggagttg aagtaatttt aaaagatttt ttagaaatag
    10561 cgcttgatat atatatggta aaataaaaag aattgctgtg atatcaatag atttggggga
    10621 ttttttaata tggtactgga taaggcaagt tgtgatttgc ttcaatattt gatggatcaa
    10681 gaaacgtcca aaacgattat ggcgatttcg aaagatttga aagagtcaag aaggaaaatt
    10741 tattatcaca ttgacaaaat caatgctgct ctgggtgacg aggcgcttca catcattagt
    10801 attccacgaa ttggtattca cttaacggaa gagcagagag atgcttgttg taaactatta
    10861 tcggaagtag attcgtacga ttatatcatg agtgcgcatg aacgtatgat gataatgtta
    10921 ctatggatag gtatttctaa agaacgtatt acgattgaaa aattgataga gttaacagag
    10981 gtatctagga atactgttct caatgatttg aatagtattc gttatcaact aactttggaa
    11041 caatatcagg tgatcttgca agtgagcaag tcacagggat accaccttca tgcccaccct
    11101 cttaataaaa ttcagtatct tcaatcgctt ctatatcata tttttatgga agaaaatgcc
    11161 acttttgtat ctattttaga agataagatg aaagagaggt tagatgatga gtgtttgctt
    11221 tctgttgaaa tgaaccaatt ttttaaggaa caggttcctt tagttgaaca agatttaggg
    11281 aagaaaataa accatcatga aataactttt atgttgcagg ttctacctta tttgctgtta
    11341 agctgtcata atgttgaaca gtatcaagaa agacatcagg atatagagaa agaattttct
    11401 ttgataagaa aaagaataga gtatcaggtg tctaagaaat taggagaacg gttgtttcaa
    11461 aagtttgaaa tttctttgtc aggacttgaa gtttctcttg tagctgttct cctcctctcc
    11521 tatcgtaaag atttggatat tcatgcagaa agtgatgatt ttcggcaatt aaaacttgct
    11581 ttagaagaat ttatctggta ttttgaatca caaatccgaa tggagattga gaacaaggat
    11641 gatttgttac gaaatttgat gatccactgt aaagccttgt tatttagaaa gacttacggt
    11701 attttttcta aaaatcctct aacaaaacaa attcgatcca agtatggaga attattttta
    11761 gtcactagaa aatctgcgga aattttagaa ggagcatggt ttattcggct aacagacgat
    11821 gatattgcct atttgacgat tcatattgga ggatttttaa aatatacacc atcatctcaa
    11881 aaaaatatga aaaaagttta tctcgtttgt gatgaaggtg ttgcggtttc gagacttttg
    11941 ctgaaacaat gcaaacttta ttttccaaat gagcaaattg acactgtatt tacaacagaa
    12001 caatttaaga gtgtggaaga tattgcacaa gttgatgtag tgattactac taatgatgat
    12061 ttggatagca gatttccgat tttaagggtt aatcctatcc ttgaagcaga agatattttg
    12121 aaaatgctag actatcttaa acacaatata tttcgtaata agagcaaaag tttcagtgaa
    12181 aatctttcta gtcttatttc gtcttatatt gtagacagca agttggctag taagttccaa
    12241 gaagaggttc aaacacttat aaatcaagaa atagtagttc aagctttttt ggaagatatt
    12301 tgaaggacag tccaatgatg aacacaaacc tgtgtttttc ttggtctttt ttagtgtttt
    12361 gaagggtggt atactaatct caaagataac aattatatcc aaaggaggca acatatgcca
    12421 aacgtcaaag aaattacaag agagtcatgg attttagcca ctttcccaga gtggggaaca
    12481 tggttgaacg aagaaatcga agaagaagtc gtacctgaag gcaactttgc catgtggtgg
    12541 ctaggcaact gtggtacttg gattaagaca ccagctggtg ctaacgttgt catggacctt
    12601 tggtcaaacc gtggaaaatc aaccaaaaaa gtgaaagata tggttcgtgg gcaccaaatg
    12661 gcaaatatgg caggtgttcg taagctgcaa ccaaacttgc gtgttcagcc aatggttatc
    12721 gatccatttg ctatcaacga actagactat tacttagttt cacacttcca cagtgatcat
    12781 atcgacccat acacagctgc agcaattctc aataatccta agttagagca tgttaagttt
    12841 atcggtcctt accactgtgg acgaatctgg gaaggatggg gtgttccaaa agaacgtatc
    12901 atcgttgtta aaccaggtga cactatcgaa ttaaaagata tgaagattca tgcagtagaa
    12961 tcatttgacc gtacttgctt ggtaactctc ccagtgaacg gtgctgatga gacaggcggt
    13021 gaacttgctg gcttggctgt tacagatgaa gaaatggctc aaaaggctgt taactatatc
    13081 tttgaaacac caggtggaac catctatcat ggtgcagatt ctcacttctc aaactatttt
    13141 gcaaaacatg gtaaagactt taaaattgat gttgctttga ataactatgg tgaaaatccg
    13201 gtaggtatcc aagacaaaat gacatctatc gaccttcttc gtatggcaga aaatctgcgt
    13261 accaaagtca ttatcccagt tcactatgat atctggtcta acttcatggc ttctactaat
    13321 gagattctag aactttggaa aatgcgaaaa gatcgcttgc aatacgattt ccatccattt
    13381 atctgggaag ttggcggtaa gtacacttat cctcaagatc aacacttagt agaataccat
    13441 catccacgtg gttttgatga ttgttttgaa caagactcta acattcaatt taaagctttg
    13501 ctataatata aaaatattct ttggaggtta tccgtatgtt gcatgatacg gataattttc
    13561 atataatagt aaaatagaat gtgtgattca ataatcacct caaatagaaa ggaaattcta
    13621 tgtcaaatct atctgttaat gcaattcgtt ttctaggtat tgacgccatt aataaagcca
    13681 actcaggtca tccaggtgtg gttatgggag cggctccgat ggcttacagc ctctttacaa
    13741 aacaacttca tatcaatcca gctcaaccaa actggattaa ccgcgaccgc tttattcttt
    13801 cagcaggtca tggttcaatg ctcctttatg ctcttcttca cctttctggt tttgaagatg
    13861 tcagcatgga tgagattaag agtttccgtc aatggggttc aaaaacacca ggtcacccag
    13921 aatttggtca tacggcaggg attgatgcta cgacaggtcc tctagggcaa gggatttcaa
    13981 ctgctactgg ttttgcccaa gcagaacgtt tcttggcagc caaatataac cgtgaaggtt
    14041 acaatatctt tgaccactat acttacgtta tctgtggaga cggagacttg atggaaggtg
    14101 tctcaagcga ggcagcttca tacgcaggct tgcaaaaact tgataagttg gttgttcttt
    14161 atgattcaaa tgatatcaac ttggatggtg agacaaagga ttcctttaca gaaagtgttc
    14221 gtgaccgtta caatgcctac ggttggcata ctgccttggt tgaaaatgga acagacttgg
    14281 aagccatcca tgctgctatc gaaacagcaa aagcttcagg caagccatct ttgattgaag
    14341 tgaagacggt tattggatac ggttctccaa acaaacaagg aactaatgct gtacacggcg
    14401 cccctcttgg agcagatgaa actgcatcaa ctcgtcaagc cctcggttgg gactacgaac
    14461 catttgaaat tccagaacaa gtatatgctg atttcaaaga acatgttgca gaccgtggcg
    14521 catcagctta tcaagcttgg actaaattag ttacagatta taaagaagct catccagaac
    14581 tggctgcaga agtagaagcc atcatcgacg gacgtgatcc agtcgaagtg actccagcag
    14641 acttcccagc tttagaaaat ggtttttctc aagcaactcg taattcaagt caagatgcct
    14701 tgaatgttgt ggcagctaaa ttaccaacct ttctaggtgg atcagctgac cttgctcact
    14761 caaacatgac ttatatcaag acggatggac ttcaagacga tgccaatcgc ttgaatcgta
    14821 acattcagtt tggtgttcgt gaatttgcaa tgggaacaat cttgaacggg atggcccttc
    14881 atggtggact tcgtgtatac ggtggaactt tcttcgtctt ctctgactat gtgaaggcag
    14941 ctgtccgctt gtcagcctta caaggacttc ctgtgactta tgtctttacc catgattcaa
    15001 tcgcagttgg ggaagatggt ccgactcatg aaccagttga gcatttagca ggtcttcgtg
    15061 ctatgccaaa tctaaatgtt ttccgtccag cagatgcgcg tgaaacgcaa gcagcttggt
    15121 accttgcagt gacaagtgag aaaacaccaa ctgcccttgt cttgacacgt caaaatttga
    15181 ctgttgaaga tggaacagac ttcgacaagg ttgctaaagg tgcttatgtt gtatatgaaa
    15241 atgcagccga ctttgatacc atcttgattg cgacaggttc agaggttaat cttgctgtct
    15301 cagctgctaa agaattggct agtcaaggcg aaaaaatccg cgtagtcagc atgccatcta
    15361 cagatgtctt tgataaacaa gatgcagctt acaaggaaga aattcttcca aatgcagtcc
    15421 gccgtcgtgt tgcagtcgaa atgggtgcaa gtcaaaactg gtacaaatat gttggtctcg
    15481 atggtgccgt tctaggtatt gataccttcg gagcctctgc cccagcacca aaagtattgg
    15541 cagaatatgg ctttactgta gaaaatcttg taaaagttgt tcgaaacttg aaataatcct
    15601 aaaaatcagg gcgtaagctc tggtttttct taccagaaaa gtaaggtaca atcttgtaaa
    15661 agtagctgaa atttgatata gtagtcctat gtaaaagaca aaggagaaaa caatgaatcc
    15721 aaatattact tttttaatca tgcttgtagg tatgatggcc ttgatgttct ttatgcaacg
    15781 ttctcaaaag aaacaagctc aaaagcgtat ggaaagctta aataaactac aaaaaggcta
    15841 tgaagtgatt acaatcggtg gactttatgg aacagtcgat gaagtagata cggagaaggg
    15901 aacaatagtt cttgacgtag agggagttta cttgactttt gaactagctg ctatcaagac
    15961 agtattaccg ctgaaagaaa cagcttcact agaaggcgca attgaaaaat aagacgggat
    16021 cacgaactcc cgtttttcta taaaagaaag gaaatgggat gaaaaaatta gtctttgtct
    16081 gtctgggaaa tatttgccgt agccctatgg ccgagtttgt tatgaaatca atgacagata
    16141 actacgaaat ccaaagtcga gcaacttcct cttgggaaca tggcaatccg attcataagg
    16201 ggactcaggg aatttttcaa gagtatgaga ttccttatga caagaacaag acatcgcttc
    16261 agattagtaa ggaagatttt gaagcctttg attatattat cggaatggac gcttcaaata
    16321 tttctgactt acgtcagatg tgtccagtag actgtcaaga taagatttac tcattttcat
    16381 ctgaaagtgt tccagaccct tggtatacag gagattttga agaaacctat cgacgtgttc
    16441 aagagggctg tcaagcttgg ttagaacgtt tagaaaagga gagttaaggt ggaaaatctt
    16501 acgaattttt acgaaaagta tcgtgtctat ctgactcgtc cacgtttaga gcttttggca
    16561 gtagttacca ttgttttctg tgctgtactc gtcttttttc taaatattcc aggaaaaggt
    16621 gtcttaaaac tcgataatgg aacgattgtt tatgatggca gtcttgtccg cggtaaaatg
    16681 aatggccaag gtaccattac cttccaaaat ggagaccaat atacaggtgg cttcaacaat
    16741 ggagccttca acggaaaagg tacctttcaa tctaaagaag gctggaccta cgaaggtgat
    16801 tttgtaaatg gtcaggctga aggaaaaggg aaactaacaa cagaacaaga agtcgtttat
    16861 gaaggaactt ttaaacaagg cgtttttcaa caaaaataaa gcctccttat caaaggaggt
    16921 attattagaa tcgcaaggta agcgcttacc tgcaaatccc tttctttcca aatccctctt
    16981 ccaagcaagt ttgtgaaata aaaaatattt gaaataaatt tcacaaactt caaagataaa
    17041 acctgataag aaaagaaaat gagaaaagtt tcacaagagt ttaaaaattc tttgtgaaat
    17101 gtttatgaaa ctgtttacaa agttgaaata atgcgttata ataaacttgt gaaaaaatta
    17161 acaaaggata tcgttccttg aaagctatgg aggaaaatat ggctgataaa aaaactgtga
    17221 caccagagga aaagaaactc gttgctgaaa aacacgtaga tgagttggtt caaaaagctc
    17281 tagttgccct tgaagaaatg cgtaaattgg atcaagaaca agttgactac atcgttgcca
    17341 aagcatcagt agcagctttg gatgcccacg gagaattggc tttacatgcc tttgaagaaa
    17401 caggacgtgg tgtatttgaa gataaagcaa ctaagaactt gtttgcttgt gaacacgtgg
    17461 taaacaacat gcgtcacact aaaacagttg gcgttatcga agaagatgat gtaacaggat
    17521 tgaccctgat tgctgaacca gttggtgttg tttgtggtat cactccaaca acaaacccaa
    17581 catcaacagc gatcttcaaa tcattgattt cattgaagac acgtaatcca atcgtctttg
    17641 ccttccatcc atcagctcaa gaatcatcag ctcatgcagc tcgtatcgtc cgcgatgcag
    17701 ctatcgcagc tggtgctcct gaaaactgtg tacagtggat cactgaacca tctatggaag
    17761 caactagtgc ccttatgaac cacgaaggta ttgcaacaat ccttgcaaca ggtggtaatg
    17821 ccatggttaa agccgcatac tcatgtggta aaccagctct tggggtaggt gccggaaacg
    17881 ttccagctta tgttgaaaaa tcagcaaaca ttcgtcaagc agcacacgat atcgtcatgt
    17941 ctaaatcatt tgataacggt atggtctgtg catctgaaca agcagttatc attgataaag
    18001 aaatttacga tgaatttgta gcagagttca aatcttacca cacttacttt gtaaacaaaa
    18061 aagaaaaagc tcttcttgaa gagttctgct tcggcgtcaa agcaaacagc aaaaactgtg
    18121 ctggtgcaaa attgaacgct gacatcgttg gtaaaccagc aacttggatt gcagaacaag
    18181 caggatttac agttccagaa ggaacaaaca ttcttgctgc agaatgtaaa gaagttggcg
    18241 aaaatgagcc attgactcgt gaaaaattgt caccagttat tgcagttttg aaatctgaaa
    18301 gccgtgaaga tggtattact aaggctcgtc aaatggttga atttaacggt cttggacact
    18361 cagcagctat ccacacagct gacgaagaat tgactaaaga atttggtaaa gctgttaaag
    18421 ctattcgtgt tatctgtaac tcaccttcta cttttggtgg tatcggggac gtttacaatg
    18481 ccttcttgcc atcattgaca cttggatgtg gttcttacgg acgcaactca gttggggata
    18541 acgttagtgc cattaacctc ttgaatatca aaaaagtcgg aagacggaga aataacatgc
    18601 aatggatgaa acttccttca aaaacatact ttgaacgtga ttcaattcaa taccttcaaa
    18661 aatgtcgtga cgttgaacgt gtcatgatcg ttactgacca tgccatggta gagcttggtt
    18721 tccttgatcg tatcatcgaa caactggacc ttcgtcgcaa taaggttgtt taccaaatct
    18781 ttgcggatgt agaaccggat ccagatatca caactgtaaa ccgtggtact gagattatgc
    18841 gtgccttcaa accagatacc atcatcgcac tcggtggtgg gtctccaatg gatgctgcca
    18901 aagtaatgtg gctcttctac gagcaaccag aagtggactt ccgtgacctt gtccaaaaat
    18961 tcatggatat ccgtaaacgt gccttcaagt tcccattgct tggtaagaag actaaattca
    19021 tcgcgattcc aactacatct ggtacaggat ctgaagtaac accatttgcc gttatctctg
    19081 ataaagcaaa caaccgtaaa tacccaatcg ctgactactc attgacacca actgtggcaa
    19141 tcgtagatcc tgctttggta ttgacagttc caggatttgt tgctgctgat actggtatgg
    19201 acgtattgac tcacgcgaca gaagcatacg tatcacaaat ggctagtgac tacactgatg
    19261 gtttagcact tcaagccatt aaattggtct ttgaaaatct cgaaagctca gttaagaatg
    19321 cagacttcca ctcacgtgag aaaatgcata acgcttcaac aatcgctggt atggcctttg
    19381 ccaatgcctt cctaggtatt tctcactcaa tggcccataa gattggtgcg caattccaca
    19441 caatccacgg tcgtacaaat gctatcttgc ttccatacgt tatccgttac aacggtacac
    19501 gtccagctaa gacagcaaca tggcctaagt acaactacta ccgtgcagat gaaaaatacc
    19561 aagatatcgc acgcatgctt ggacttccag cttctactcc agaagaaggg gttgaatctt
    19621 acgcaaaagc tgtctacgaa ctcggtgaac gtattgggat ccaaatgaat tttagagacc
    19681 aaggaattga cgaaaaagaa tggaaagaac attctcgtga attagccttc ctggcttatg
    19741 aagaccaatg ttcaccagct aacccacgtc ttccaatggt agaccatatg caagaaatca
    19801 tcgaagatgc atactatggc tacaaagaaa gaccaggacg ccgtaaataa ttgtttatca
    19861 gtctagaagc aagacaaaaa ctcaatttga gggaaagatc cagtaatttt tctatgataa
    19921 aaggcatcct atcaaggttt ttgaacacct gataggatgc ctttttatga tattgaggcc
    19981 tttttgccct ttttgaaaaa ctagaataga aacaaaatat ataatagatt gaaactggaa
    20041 tagtacactt ctgcttctaa aacattgtta gaattcgatt tgactgtcct gatcgatttg
    20101 tcctattcct atttcatttt actatataaa aaatatagta tagtagactg aatctaaaat
    20161 agtacgaaac aattgctaaa acatttatag aaattaattt tactttcctg atagagttgt
    20221 tcacatctta tttcaattca ctatagttta atttaagagt agtatttact aaggcccaat
    20281 taaaatcaaa gagcaaacta gaaaacgagt gccattcagc tcaaaacact gatttgagat
    20341 tgcagataag actagcccct cattaacagg tttacgataa aacgatgaca aggtgtgttg
    20401 ctttttgatt tctaaagagt ataatgatag atctctataa aataagtgcg aaggaaatga
    20461 gcttttatag tcctttcgtt ttaaaatact atctcagatg ttcttatatc gacaagaagt
    20521 ttttgagtca ttccctcatc atacatatta aataaatagt ggctcattca attttttact
    20581 agaataataa gctagtatag taaactgaaa taagatataa acaaataaat tggagcttaa
    20641 catctatttc cagcaatttt ttagaaactg cagtggacta ttctaaattc aacacattat
    20701 aaaaactaga gtaaaagaaa aggattggat cttgtgtaat gcaggatcta atcctttcaa
    20761 tcattttgtc caacttttgg aggttcctac aatgtagccg tcattaataa agacagatgg
    20821 gaacgacagt gttcctattt attttgatag agatcgatga attctttaga tagcaactga
    20881 ataatctctg ttgaagccat ttggtcttct gcatgcataa atagcaagga gaatcctatt
    20941 ttttctccag tagcttcttt ttgtatgaga ttagagtgaa tcttgtgcgc ttctactaag
    21001 gagtcttccg cttcttcaac tttaattttc gcttctttta aatttcctgc cttagctagt
    21061 tggatggctt caataaagga tgatttggct gctccactat tggcaatgag ctgaaaacag
    21121 atatattcca tttcttctgt catcttattt ctcctatcca tgcaagtgct tgttccagaa
    21181 cttttgctcc attcatcatt ccgtaatccc gcatatcaat ggtatctaca gggatatttc
    21241 ctgcaatttc tttcacagca agtaactcat aacgaatttg tggcccaatt agaatgacat
    21301 ctgcttcatg gatattcttt ttcgcttctg tcattgattt tgcttggata gaaatttcaa
    21361 tcccacgttc agtcgcactt tgttgcattt ttttaacaag catacttgtc gacattcccg
    21421 cattacatac taataaaatt tgtttcataa tcttaacctt ccatttcttg ctcaacaact
    21481 ttgtcattaa ctttgataaa tggaatgtat agaagaactc caagtgcaaa gatgatgaat
    21541 tgaactagaa ctgctctcac gtcccctgct gttgctaacc atgcatttaa gaatactggt
    21601 gtagtccaag gaacttgtat aaatgcagga ctcatgaatc ctgtaactgt tgctaagtag
    21661 ctgattaaaa taccaaggac tggaactgtg ataaatggaa tagctaatga aatgttataa
    21721 acgattgggt aaccgaataa tactggttca ttgatattga agataccagg tccaaaagat
    21781 aatttagcca cgtttttaga aacagcattg cgactcacta agaatgttgc tattaataaa
    21841 cataatgtag atccactacc acccattaaa gcgaatgttt gtatttgtga taagttgatg
    21901 atgtgtggaa tggcttgtcc attatttgct gcagtgatgt tttcagtaat gttaattaat
    21961 agtaatggtt ctaggatggc actgtaaata actgcttggt gaataccaaa tagccataac
    22021 atatttccta aagagtaaat aataatgacc ccgattaagc ttgtaccaat atgacgaatt
    22081 ggttcttgaa taaagattgt aatgattgag attaagttca ttccagttat attgaataat
    22141 aatgctgaaa caatcccaaa taaggagatg acagtcatga ctggaagtaa tacgctaaat
    22201 gatctactaa cagctggtgg aatattttca ccaaggttca tttgtaaagc tttaacgttt
    22261 gataattcaa tgaataattc tgttgcaata atcgctacga taaccccggc gaacattgcg
    22321 cctgtacctg tgttgttgaa tgaaagaaca cctgaaatgt ttacagcatc ttttgctccg
    22381 tcaggaacta cagaaactgt atttggcatc atcacaatta aagaaactaa tgatagcatt
    22441 gatgctgctg acgggttttc gaaatctctg tttttagcta agaaataacc aaccattaca
    22501 gcaataatca tacctgaaat acttaaagta ccgtttgcaa ttgttattcc ccaatattgg
    22561 aattttgtta atgtatcccc ttggaaaatc cacttaaata ccgtgttgtt caaaagaacg
    22621 attaaacctg ccaaaatata taatggcatt actgttacga atgcatctct tagggttttt
    22681 aaatgaattt ggttccctag tttaccagca aaggtggcaa attgatctat aaattttgag
    22741 tttttcatct gaatatctcc tctctttact cctcaatttc tacttcaaaa ccgttattgt
    22801 cacttacttt gcgataccat cttcctgagc tcttgatggt tctcttttgc gtttctaaat
    22861 caacggagat aaatccgtaa cgattcttat atgcattatt ccaagaccag caatcaaatg
    22921 cggtccaagc gtggtatcca aaacagagac ttccctcttc aatggcttta tgtagccatc
    22981 ttaaatgttc ttcataaaat tcaatacgat acacgtcatc gataactcca ttttcatcga
    23041 taaaccgtgc ttcgttttca acacccattc cgttctcact gataaaccat gggatattac
    23101 catattcttc cttcacaatc atagcaatat cataaatggc tttcggaaaa atttcccaac
    23161 cacgatatgg attcatgcga cgctccggcc attcatactc tttgaagtat tggtctggca
    23221 tccagggcgt ctgatattcc tcaggatttg cttgtgcttg aacacgtttt ggatggtagt
    23281 agtttactcc aagaaaatca accgtatttg atttcatcag ttgaagctct ttttcggtat
    23341 gactccataa cacgccatct ctctctagct gttttaccaa tctttctggg aaagttcctt
    23401 taacagctgg attcaagaag actttgttaa agaagtcttc tgtaaatcga cttgcttcta
    23461 agtcttctgg agaattactt cttggataag caggtgtcaa gtttaaaata atcccaatct
    23521 ttccatcaag tcctaatgag cgatatagtt gaatcacttt tgcactagca aggtttagat
    23581 tatagatgac ttgtacggcc tcttttccct ttccttttag atttggataa tggaaagcat
    23641 ataagtatcc tgcttctgga atgaccattg gctcattgaa agttgtccag taatgaacct
    23701 tatctccaaa gcatgtgaaa gcagtcttgg caaacttcac gaataactcc actacatgtt
    23761 tgctttccca accaccgtat ttttgaagaa gttccactgg taaatcaaaa tgatgtaaat
    23821 tcatcacaag atccatctgg ttctttttag cttcttcaat gatggcattg tagaaagcaa
    23881 taccttttgg atcaggctca cctgtctcta aattcttgat gagtcgactc cattggatgg
    23941 aagtgcggaa agaattaact ccaatttcct tcatcaagtg gaaatcttcg gtgtaagtat
    24001 gaaaaaagtt actggctaca agaggtccga cattatcgaa aaaatcttct ggatgcgttt
    24061 tgaaccagta gtccatcaca ttttcatgta cttttccata ttgaccttct gtctgaggtc
    24121 cgctagaagc agctccccac caaaacagat taggaaatac taactttttt ttcatgctca
    24181 acctcctttc tattatgcta tacataaagt atagcataat tttaaaattt gtctagacat
    24241 ttttaaaaat tgttgataca tatattgtgt ttgcctcatt tcttgaactt tgttatacta
    24301 ctattagaat attatagaga gaaccagatt aaatgagtac aaaatattta tttatttaca
    24361 atgagattcg tgaaaagatt ctctgtaata aatataccat gaacgaacaa ttgcctgatg
    24421 aaatgacatt agctaaacag tttgcctgta gtcgaatgac gatcaaaaaa gctttagact
    24481 tgttagtttc tgagggctta atttttagaa aacgtgggca gggaaccttt gttctctctc
    24541 gtggcagctc aaaaagaaaa ttaatcgttc cagaaagaga tatccgggga ctgacaaaaa
    24601 tatctgaaga tgctcattct acaattgact cgaggattat tcacttcaaa ttagaatttg
    24661 caaatgaatt tttagcagaa aaactacagg tcgctttgca gagtccagtt tataatattt
    24721 accgcctgcg tattattgac ggtaaacctt atgttctgga acaaacttat atgagtaccg
    24781 atgttattcc aggtattact gaagatattt tacaaaaatc gatttacaat tacattgaag
    24841 gaaagttagg attgcatatt gccagtgcta caaaaatctt gcgagcttct tctagttcag
    24901 aaaatgagca acattacttg cagctccttc caacagaacc ggtatttgaa gtagaacaag
    24961 tggcttattt ggataacgga actccgtttg agtactcgat tagtcgtcat cgctatgatt
    25021 tatttgaatt taattctttt gcattacgac attcctccta ggagaaaatg tgaaaatgaa
    25081 gccaatcttt tacaggctct agtttaagaa aaatttaaaa cagggcaaga aggtcccatc
    25141 tatgcttaaa tggtttctct tttctaaata agatggcttt aaaagagtga tcgttttatc
    25201 catcatgttg aaaaatatct tcgtatagct tatagagtag gtactgaaat tgttcacctg
    25261 atctacttct tatagttatt tagttttaaa tagtgtttca aacattctta cactgacgag
    25321 aagtttttga gtcttttctt gtaacacata tagtatactg aggttagaat agtagactgt
    25381 gacttctaac aaattgctag aaatgaattt caatctccca atttatttgc ttatatatta
    25441 ttttaatata ttaaataaat tctggatcat aatcatttaa aaaaatttta tttttttatt
    25501 tttcattacg aataatatag atgaagggga aagagtatga aaacagaact gtttcttttg
    25561 ctattagttc aaaaggagaa aaaatgaaag tagaaaatat ttcgtatagg gtggatcatc
    25621 gtatattgtt tgataatatt tcttttgata cttcgagttc agacgtgaca ttaattactg
    25681 gtaaaaatgg tacaggaaag tcaactttac tatagtggat tgaaactaga atagtacaca
    25741 tctacttcta aaatattgtt agaaatcgat ttgactatcc tgatctattt gtcctgttct
    25801 tatttcattt cactatatct caaattgagt atgacgaagt gcgctcccat gtcctgggaa
    25861 cgcactttct tcatattttt catattcttg aatccatcga taaagactat tgggatgaat
    25921 ttttaaagtt gaactaatca tttttacagg atgaggttta cagcagagag tttgaaggct
    25981 ttatcaaagg tttttcttgg cataatgact tttcctcgtt tccacttaat tttgtgtcta
    26041 ctttattata ccaagtccac ccttaagtta gataataaat ctaacttaag gaagctagaa
    26101 ggatgagaat ccaggtggtc aagagtccca aacttaagct gattgggaca cccagaataa
    26161 tttgcttttt gaaggcaagg ccacgttcct ctatattggg aagtgagagt tgaatgagag
    26221 aaccagctga tgaaaagggt gagatattag tagatagagc gccaataacg gtggctgttg
    26281 tgagtaagtg aatatcaatc tggggatttt gagcactgat gatagcaatg atgggaaaga
    26341 gggctggagc tacaacggat agggtggaac taaagagtga catcaccccg gctatcacac
    26401 aaaagaacag aggtaaccag aaatgaggaa tggatgttgt catgaggtgc cctatcagtg
    26461 tgactaaacc tgacttgacc gctagagaca ttagtaagct catgccgcag agcatgataa
    26521 ttgtagccca gggaacttta gccaaaatgg cttcttgctt ccctaatttg agccttaagg
    26581 cgaggcagac catgagtatt gagacaaagc caatatcaaa tgtttttcga taagtagcta
    26641 tccaggcgat gtttgggaaa atgagatgca acaagggaaa aagccaaacc aaaaccatgc
    26701 tgctgatcat gagcaaggtg gtttgtcttt gaaccttgct gaggagtggt ggttggtcaa
    26761 tagtcaagga tgagtttgtt cttcccttac tatagtgact gtaacaggat aataaaagca
    26821 agacaatgag tgggtagata atgctgacga taaagatatg attgccaagt gaaaaagctt
    26881 gctcttccca tcccatttgc ttaaacaggc cttgaaagac aatgcctgag ctactggtta
    26941 tcaaattagc ccctcctgaa gctccccaat tgacggcttg agctccaatc aaagggtgtt
    27001 tgtccgcttt ttgacagaga gtaatcgcta gaggacagca aacggccata gtagtgaaaa
    27061 atccagcacc taaagcagac aaaagggttg ccatcaggta taaaatcatg tagagggcgt
    27121 tagggtaggt gcgtgtgcgg tagagaatgt gttgagccaa aacatcaaga gtaccgttag
    27181 ttattgcaaa gttataaaag agagagacgc taaaaatggt aaaaaagagt gaggttggcc
    27241 aaaaatgaag aagttctttg gggcttaatc ccatgagagt ggttgcgatg aggtaagaaa
    27301 aagcaatagc cagcaggcca atattgattt tggtgcggta accaattcca atggctagag
    27361 caatggcgct aatcattatt aaatgaatca ttgaattgtc ctttcagtta gaatatggaa
    27421 ataggttggc aattttggcg ctcaaaagac cacctgtttc ctattggtac ttgactatta
    27481 tacacaaaaa aaatacaatt gtcttgacaa ttgtattgac acttgttaga attaaaaatg
    27541 aggtattcag gcttgtgatt tcctatggaa gttaatagtg attgcctcta atgcttacaa
    27601 gtgatattaa aaatagagga cctagtgatg tcaatcattt caactgattt aacccctttt
    27661 caaatagatg atacattgaa agcagccttg cgagaagatg ttcattccga agattacagt
    27721 accaatgcca tttttgatca tcatggccaa gccaaggtgt cgctttttgc caaggaagct
    27781 ggtgttttag cggggctaac cgtttttcaa agggttttta ccctatttga tgccgaggtg
    27841 accttccaga atcctcatca atttaaggat ggggatcgtt tgactagtgg cgatttggtt
    27901 ttagaaatca taggctcggt gagaagtctc ttaacatgtg aacgcgttgc cttgaatttt
    27961 ttacaacatt tatcagggat tgcttcgatg acagctgctt atgtagaagc cttaggcgat
    28021 gattgcatta aggtatttga tactcgaaaa actactccta atttacgtct ttttgagaaa
    28081 tatgcagtga gagttggcgg tggctataat catcgcttta atttatcaga tgctatcctg
    28141 ctaaaagaca atcacattgc ggcagtaggt agtgttcaaa aggcaattgc tcaagcgcgt
    28201 gcctatgccc cttttgtgaa aatggtcgag gtggaagtgg aaagccttgc tgctgccgaa
    28261 gaagctgcgg cggcgggtgc tgatattatc atgttggata atatgtcatt ggaacagatt
    28321 gaacaggcca ttaccctaat tgcaggacgt tctcggattg aatgttctgg aaatattgat
    28381 atgaccacta ttagccgttt tcgtggttta gcgattgatt acgtctccag tggtagttta
    28441 acccatagtg ctaagagtct tgatttttcc atgaaggggt taacctacct tgatgtctaa
    28501 gttgtaaaat aaactaactt tttaaaggat gtctttcctc tagaacgagt tttatgtcag
    28561 atagtttaaa cgcctcttca a
//
LOCUS       DAVBIC010000029        27266 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.029, whole genome shotgun sequence.
ACCESSION   DAVBIC010000029 DAVBIC010000000
VERSION     DAVBIC010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 27266)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27266)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27266
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.029"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            219..1901
                     /locus_tag="VQ664_001207"
     CDS             219..1901
                     /locus_tag="VQ664_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2789373.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQTAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHRPVDRIV
                     LINDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLANLDNMSIS
                     KGQVQLQNELVKETPELQSLFKLEDVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKAISSFIQTEGRYLWEKQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEKEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHRKGHTIVMITHDMQLMLDYSDRVLVMVDGELIA
                     DTVPASLLSDPELLVKANLKETSIFNLAKKLDVDPLDLTAFYKERREGCKLN"
     gene            1886..2716
                     /locus_tag="VQ664_001208"
     CDS             1886..2716
                     /locus_tag="VQ664_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HET2789374.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRMLL
                     LIAIFSVFLLYLSEIRFKDVSFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGVYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVASLLLSLQNQGRFYNPWK
                     "
     gene            2909..3412
                     /locus_tag="VQ664_001209"
     CDS             2909..3412
                     /locus_tag="VQ664_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HET2789375.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFISQMKGKLYLISKFAEKVYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     regulatory      3466..3700
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            3865..4428
                     /locus_tag="VQ664_001210"
     CDS             3865..4428
                     /locus_tag="VQ664_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET2789376.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTIGLTVAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYILLKPTLKHYER"
     gene            4442..5068
                     /locus_tag="VQ664_001211"
     CDS             4442..5068
                     /locus_tag="VQ664_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HET2789377.1"
                     /translation="MKGSFALLLFVILGYMVKFYPEMLVNFDQSIQTAIRGDLPDYLT
                     ILFRSLTRLIDIPVIITWVVIIAFVFYRKRWKIESFFMLGNLTLAGLLIVTFKNIYQR
                     PRPAILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKDQVWRKIVQIVLGLYLVS
                     VLVSRVYLGVHYPSDVLASLCVGLGALFIEFPFYDKLRFQWRFKGKQK"
     gene            5180..6052
                     /locus_tag="VQ664_001212"
     CDS             5180..6052
                     /locus_tag="VQ664_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000525616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2789378.1"
                     /translation="MGMLLATRLKNKRKELKLSQKELAEGICEQGQISRMEQGKYSPG
                     SELLFQLSKRLKVSMDYFFEDTEVSSLENIDKFKELSKKFLDEREYESLHYIYELEKS
                     KRARLSAKDQIYLDWIDTLVQFCYLNHQTGAVAKLEKILLSLKKSDFYYLQLGNTLAN
                     FYFDMGQEDTYQELYQLLKENLQSLSVHHLEQLELMIKFRYNYCRYLWLNERTSEAIE
                     EITETIAICKRYNSSYRLADLYCLLGSISEGFAERDRILGFYQVSYQLYKHEENQRMM
                     LEIEKEMKLLESED"
     gene            6182..6319
                     /locus_tag="VQ664_001213"
     CDS             6182..6319
                     /locus_tag="VQ664_001213"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789379.1"
                     /translation="MKRSQVVKRCILIALLLLFLLNVLSGSLSVTTRGVDPRPAYGVS
                     L"
     gene            6743..7657
                     /locus_tag="VQ664_001214"
     CDS             6743..7657
                     /locus_tag="VQ664_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000781144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
                     /protein_id="HET2789380.1"
                     /translation="MKLYQINDGIQIFESSNLEKIVIRNYRNGKKITIDHQPLLKKLL
                     LFLEVPKREEEILLYLPELSNKTLRSVLTNFMSLNIIHCQDTLIIHKKINILIIGLGT
                     TGGYLADGLCRSNINSKLFLLDKDRVDETNVGRQIYLRDDIGQYKVDVFKQKFSDKEI
                     KVFKIFINSKKDLEKICKREGIDLVIQCGDSPSPRELGKIVNTVCDTLQIPYIVNTGY
                     MSNVVPLPEFYYPNNRYNFNYKHQFSDEKLLFSQVLSKADYMVAIQSSFVMLMQIKNF
                     IFNEEPIYYGYRGYYNSVTLAWEVEKID"
     gene            7650..8663
                     /locus_tag="VQ664_001215"
     CDS             7650..8663
                     /locus_tag="VQ664_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789381.1"
                     /translation="MTKYLELDYSHSYILEGFRKNDAFIENHKECLDMLSDKIWRDNK
                     YMNTEKNISSPTRTILSRYTCNILSSLFIDISKNSIEKLIVTCENSDLNWIYNYYKSV
                     YNGVFCELRQLIQQYCKVKDKYEKWLFIKAIINQGIRQNEKEVVEFFLKQLKDNNQGI
                     FDYINSFSFYLLKFYSKDKSRIFLEEQLDIDDFLGSDKEDYARSLVFKNYASLLPDTS
                     ELKRNIMEKCLSQTPQDTDLWKEWFETYASQKEIRQKATEIFKHGYSDISLLKLVKIE
                     PDDTESLIRMIILCTSDLNSNIARYLISFLSDGRLKEFLELFVENFDFLNIIEGKTSE
                     INF"
     gene            8647..10239
                     /locus_tag="VQ664_001216"
     CDS             8647..10239
                     /locus_tag="VQ664_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001236730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2789382.1"
                     /translation="MRLIFRIIRKDIILYSILTFLLSIAMVSEAFLMQFIVDSIKFGE
                     KKYVLISIFIVIFLILQTLLYYYQQFLTAVLSKKSAYEYRKLIFKNIQQTSLRLVTGE
                     KNDSILASLTTQIDQIEYNYFYSVYWGGYLLCQLVVAIVMSLYLNPLMSVLTICLSLP
                     NLFVALLFKNSLEQKQEELINETNSSIAVTQDLIEGITDWKIANREPNIFRVFESKTL
                     KLLEKQVKVEKFQYIVVSLNQLFSNVLYFGSWIVGGFLIIRGQLSLGSLIAFSQLLAR
                     ISYPVYASSDLLSKYISGKKIVEILSKEFIFSDESRNYPDEFNVISFEHYFTNIDEKD
                     MPFDKEFYKNKKYLLKGKSGSGKTTILKSILREYDDYSGIVKINGVDVRDIKESVLFD
                     NIAYVSQKPHLFSASLRDNLTLFSEDFTDNEIVEVLKFVELSKWANKDCLDMMLSNDD
                     IKLSGGEVKRVSLARALLMNKNILLLDEFSAGIDYETLLKIEKKLIDLDKMIIYVTHV
                     DIDRSGKQFDDVIDLDCLFISS"
     gene            10431..11334
                     /locus_tag="VQ664_001217"
                     /pseudo
     CDS             10431..11334
                     /locus_tag="VQ664_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001091364.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            11352..11489
                     /locus_tag="VQ664_001218"
                     /pseudo
     CDS             11352..11489
                     /locus_tag="VQ664_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853067.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
     gene            11517..11858
                     /locus_tag="VQ664_001219"
     CDS             11517..11858
                     /locus_tag="VQ664_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789383.1"
                     /translation="MKVNIADLHPTQLYLSEKKLQDIQMLYQSAETIQVDPISILAFG
                     DCLLITDGHHRAYQALLAGRDTISAEWDRDGGDELYHLYAQACEERKIYSVFDLKNHI
                     LPLWIGMVSFF"
     gene            11831..12142
                     /locus_tag="VQ664_001220"
                     /pseudo
     CDS             11831..12142
                     /locus_tag="VQ664_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            12270..12857
                     /locus_tag="VQ664_001221"
     CDS             12270..12857
                     /locus_tag="VQ664_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HET2789384.1"
                     /translation="MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            13247..14854
                     /locus_tag="VQ664_001222"
     CDS             13247..14854
                     /locus_tag="VQ664_001222"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HET2789385.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAADMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDVEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENSN"
     gene            complement(15413..17044)
                     /locus_tag="VQ664_001223"
     CDS             complement(15413..17044)
                     /locus_tag="VQ664_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HET2789386.1"
                     /translation="MSINWQEILFHFLGGLGLFLYSIKTMGDGLQQAAGDRLRFYIDK
                     YTSNPFFGVLVGIGMTALIQSSSGVTVITVGLVSAGLLTLRQAIGIVMGANIGTTVTS
                     FLIGFKLGNYALPMLFIGAVCLFFTKNRTVNNIGRILFGVGGIFFALNLMSGAMAPLK
                     DLQVFKDYMIELSKNPVLGVFVGTGLTLLIQASSATIGILQNLYAGNLIDLQGALPVL
                     FGDNIGITITAIIASLGANIAAKRVAGAHVAFNVIGTVVCVIFLVPFTVLIHWFEATL
                     NLAPEMTIAFAHGTFNITNTIVQFPFIGALAYFVTKIIPGEDEVVKYEPLYLDEHFIK
                     QAPSIALGNAKKELLHLGNYAAKAFDLSYKYIIDLDEKVAEKGHKTEEAINTIDEQLT
                     RYLIALSSEALSQKESEVLTNILDSSRDLERIGDHTEALLNLTDYLQRKNVEFSDAAL
                     KELEEVYRQTSDFIKDALDSVENNDIEKARSLVERHEAINKIERVLRKTHIKRLNKGE
                     CSTQAGVNFIDIISHYTRVSDHAMNLAEKVFAEQI"
     gene            17337..22316
                     /locus_tag="VQ664_001224"
     CDS             17337..22316
                     /locus_tag="VQ664_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HET2789387.1"
                     /translation="MKNPFFERRCRYSIRKLSVGACSLMIGAVLFAGPALAEETAVPE
                     NSGANTELVSGESEHSTNEADKQNEGEHARENKLEKAEGVAIASETASPASNEAATTE
                     TAEAASAAKPEEKASEVVAETPSAEAKPKSDKETEAKPEATNQGDESKPAAEANKTEK
                     EVQPDVPKNTEKTLKPKEIKFNSWEELLKWEPGAREDDAINRGSVVLASRRTGHLVNE
                     KASKEAKVQALSNTNSKAKDHASVGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDA
                     GHRNGVPVYGTLFFNWSNSIADQERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFI
                     NQETTGDLVKPLGEKMRQFMLYSKEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYN
                     YQFMQPEGDKVPADNFFANFNWDKAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKT
                     KVKWNDILDENGKLRLSLGLFAPDTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGD
                     KDWYGIANLVADRTPAVGNTFTTSFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWR
                     WWQTSTGEKLRAEYDFTDAYNGGNSLKFSGDVAGKTDQDVRLYSTKLEVTEKTKLRVA
                     HKGGKGSKVYMAFSTTPDYKFDDADAWKELTLSDNWTNEEFDLSSLAGKTIYAVKLFF
                     EHEGAVKDYQFNLGQLTISDNHQEPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADF
                     YEVYEKDGDSWKLLTGSSSTTIYLPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTT
                     FDWGMTVKDTSLPKPLAENIVPGATVIDSTFPKTEGGEGIEGMLNGTITSLSDKWSSA
                     QLSGSVDIRLTKPRTVVRWVMDHAGAGGESVNDGLMNTKDFDLYYKDADGEWKLAKEV
                     RGNKAHVTDITLDKPITAQDWRLNVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMA
                     KAAARSLGNNKVQVGFADVPAGATITVYDNPNSQTPLATLKSEVGGDLASAPLDLTNQ
                     SGLLYYRTQLPGKEISNVLAVSVPKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLR
                     VQYEGGTEDELIRLTHAGVSVSGFDTHHKGEQNLTLQYLGQPVNANLSVTVTGQDEAS
                     PKTILGIEVSQEPKKDYLVGDSLDLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQK
                     TGRQTLTLRYQGHEVNFDVLVSPKAALNDEYLKQKLAEVEAAKNKVVYNFASPEVKEA
                     FLKAIEAAEQVLKDHETSTQDQVNDRLNKLTEAHKALNGQEKFKEEKTELDRLTGEVQ
                     ELLAAKPNHPSGSALAPLLEKNKALVEKVDLSPEELATAKQSLKDLVALLKEDKPAVF
                     SDSKTGVEVHFSNKEKTVIKGLKVERVQASAEEKKYFAGEDAHVFEIEGLDEKGQDVD
                     LSYASIVKIPIEKDKKVKKVFFLPEGKEAVELAFEQTDSHVIFTAPHFTHYAFVYESA
                     EKPQPAKPAPQNKVLPKPTYQPASDQQKAPKLEVQEEKVAFHRQEHENAEMLVGEQRV
                     IIQGRDGLLRHVFEVDENGQRRLRSTEVIQEAIPEIVEIGTKVKTVPAVVATQEKPAQ
                     NTAVKSEEASKQLPNTGTADANEALIAVLASLGLASLALTLRRKREDKD"
     gene            22406..23602
                     /locus_tag="VQ664_001225"
     CDS             22406..23602
                     /locus_tag="VQ664_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HET2789388.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            23738..24265
                     /locus_tag="VQ664_001226"
     CDS             23738..24265
                     /locus_tag="VQ664_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HET2789389.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDESVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETILYVFVRVLETFMGVFVAIIVN
                     YDIDRIRLFLEKKEK"
     gene            24342..24698
                     /gene="glnR"
                     /locus_tag="VQ664_001227"
     CDS             24342..24698
                     /gene="glnR"
                     /locus_tag="VQ664_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HET2789390.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYEDQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            24735..26081
                     /gene="glnA"
                     /locus_tag="VQ664_001228"
     CDS             24735..26081
                     /gene="glnA"
                     /locus_tag="VQ664_001228"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HET2789391.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYIAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(26177..26296)
                     /locus_tag="VQ664_001229"
     CDS             complement(26177..26296)
                     /locus_tag="VQ664_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HET2789392.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
     gene            26784..27266
                     /locus_tag="VQ664_001230"
                     /pseudo
     CDS             26784..27266
                     /locus_tag="VQ664_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187281.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
BASE COUNT         8591 a         4565 c         5791 g         8319 t
ORIGIN      
        1 tacggcaagg cgaaactgac gtggtttgaa gagattttcg aagagtataa aatgatgggg
       61 aaggctgggc aactagtctt tttcgatgtt tatagattag ttaggcaagt aagctaggat
      121 aggaatcttt ttggtgctaa gattttaaga gaagagactg caagaagggc ttgatttatg
      181 ataaaataga agtctaagaa gcgaatgaag agagtaagat gaaagaagct ataattgagt
      241 ggaaggattt ctctttccgg tatgaaacac aacaagaacc gaccttgcaa gggatagact
      301 tgaccattta caagggagag aaagtcttaa ttgttggacc atctggatca ggtaaatcta
      361 ccttgggtca gtgtttgaat gggattattc ccaatattta caagggtcag acatatggag
      421 aatttttgat aaagggtcaa acagcctttg atatgagcat ctatgataag tctcatctgg
      481 ttagcacagt tttgcaggat acagatgggc agtttattgg cttgtctgtg gcagaagatt
      541 tggcgtttgc tctggaaaat gatgtgacag ccctagatga gatgaaaggt cgtgtttata
      601 aatgggctga aaagctggac cttcttcctt tactggatca gcgtcctcag gatttgtcag
      661 gtggacaaaa gcagcgagtc agtctggctg gtgtcttgat tgatgaaagt ccgattctct
      721 tgtttgatga gccactcgcc aatctagatc ccaagtcagg tcaggatatt atcgaattga
      781 ttgaccagat tcataaggaa gaggggacga cgactcttat tatcgagcac cgtttggagg
      841 atgttctgca tcgccctgtg gatcggattg tcttgataaa cgatggtcgt atccttttta
      901 atgggagccc tgaccagttg cttgcgactg atttattgac tcaaaatgga attcgagaac
      961 ccctttatct aaccactctc cgtcaattag gtgtggactt agtcaaggaa gaacagttag
     1021 cgaatctgga taacatgtct atctcaaaag gtcaggttca gctgcagaat gaactggtaa
     1081 aagaaactcc agaattgcag tcactcttta aattagagga cgtgtctttc tcttatgatg
     1141 atagaccgat tttaaaatcc ctacatttag atattaaaaa gggtgaaaag attgctattg
     1201 tcggaaaaaa tggagcaggg aaatcaactc tagccaaggc tataagtagc tttattcaga
     1261 cggaaggacg ctatctttgg gaaaaacagg atataaaagg cgattctgtt gcagagcggg
     1321 cggaacgagt aggctatgtg ctacaaaatc ctaatcaaat gatttcaacc aatatgattt
     1381 ttgatgaggt ggctctaggg ctccgtttgc gaggtgtgga tgagaaggaa attgaaacga
     1441 gagtctatga aaccttgaaa atctgtggac tttatgaatt ccgtaattgg cctatttctg
     1501 ccctgtcatt tggtcagaaa aaacgtgtca ccattgcttc aattttggtc ttaggagctg
     1561 aaattattct cctagatgaa ccgactgcag gtcaagatca gaagaactat actgagatta
     1621 tggaatttct cgaagagtta catcgaaaag ggcataccat tgtcatgatt acccatgata
     1681 tgcaattgat gctggattat tcagaccgag tccttgtcat ggtggatgga gaattgattg
     1741 ccgatactgt tccagccagt ctgttgagcg atcctgagct gttagtaaaa gccaatctaa
     1801 aagaaacctc catctttaac ttggctaaga aactagatgt ggatccactg gatttaacgg
     1861 cattttacaa agaaaggaga gagggatgca agctaaatta atcggttacc agcatagaga
     1921 tactgtgatt catcgcttgt caggagctgg gaaacttctc tttttcattc tggtatcatt
     1981 ggcggccatg attagctatg ataccagaat gctcttgctg attgccatct tttcagtctt
     2041 tctcctctat ttatcagaaa ttcgctttaa agatgtttcc tttgtagccg tttttgcgac
     2101 ggtatttgcc gttttaaacg ttttgatggt ctatctcttt tctcccgagt atggggttgg
     2161 actttatgga gagagaagtg tgatttggca gggaatcggt gtctacactc taaccagcca
     2221 ggagctcttt tatctgctaa atttggccat taagtatctt tgcaccattc ctctggctat
     2281 tatctttttg atgacaaccc atcctagtca gtttgcttcc agtttaaatc aaattggtgt
     2341 gccctataag attgcttatt ctgtcagcct gaccttgcgc tatattccag atttgcagga
     2401 agaattcttt actatcaaga tgtctcagga ggcgcgtggg atggaattat ccaagaaagc
     2461 ttctcttatg caacgaatca aaggcaatct gctcattatt acgcccttga tttttagctc
     2521 gctagaacgc attgatacca ttgcgactgc catggagctt cgccgctttg ggaaagaaaa
     2581 aaaacgcaca tggtatagtt atcaggcctt gaaaaaagga gactatatta ccttgctctt
     2641 ggcaaccttg tttttagtag ctagtttact acttagcttg cagaatcagg gacgatttta
     2701 caacccttgg aaatagcttg aaaaaattga aaaaatcaag tcgtttctat tgacaatgat
     2761 tctgaaagtg ttatactaag aaagtagttt cgctgattta cttcaaacct gttgtgaggt
     2821 aagttaacga tgccttaacc acgctgtttg ctgagcttga ctccgggcag tgtggctatt
     2881 tttttgcaat ggtgaaagga agcaagtcat gacaaatcac attgtattat ttgaacctca
     2941 aattccacaa aatacgggca atatcgcgcg tacttgcgct gcgaccaatt ctcccctcca
     3001 catcatcaag cctatgggct ttcctattga tgaccgcaag atgaagcggg ctggattgga
     3061 ttactgggat aagctagaga tttattttta cgagagtttg gaagatttca tatctcagat
     3121 gaagggaaaa ctctatctga tttcgaaatt cgcggaaaaa gtctattctg aggtggattt
     3181 atcgactgac gaggaccatt attttctctt tggacgtgaa gacaagggct tacctgaaga
     3241 ttttatgcga gaacatcctg agaaggctct ccgtattccc atgaatgatg aacatgtccg
     3301 cagtctcaat gtgtctaata ccgtctgcat gattgtctat gaggctcttc gccagcagaa
     3361 ctttgcaggt cttgaactcg tccataccta tgaagtggat aaattgaaat aaaaaatgaa
     3421 aatgaacaaa atgcttgcgc ttgcaagcgt tttttgttat gataaaagag tcttcagggc
     3481 agggtgtgat tcccgaccgg cggtgacttt aactaggaaa tgatcttttc cttttatact
     3541 ttgttgacaa gctttgccta accagaagtt atgcctacag cttgtcgcct agtctaaaag
     3601 aaaaatctct atttccttct ctttaaagaa gtccgcgagc gcaagctgat gtggtgagat
     3661 tccacaaccg acagtatagt ctggatggga gaagacgaaa gaatagcttt gtctgttttg
     3721 atagatttat agccggattg taaccacttg ctttgttttt ctttaataga gtaggaggga
     3781 acttttggga tataaaaagt gagaatagat agaggaatcc tttccaactt cttctgattt
     3841 tatagaaaat tggaggaacc tgttatgaca aacacacgtc gactttcgac cattgcaatt
     3901 ttatcagcca tctcatttgt gctgatgtac tttgactttc cgcttttacc agcggcatct
     3961 ttcctcaaga tcgaatttag tatcttgcca gtccttgtgg gtctggtggt catggatttg
     4021 cctgctgctc taggagtgct cttgcttcgc tcactcttga aattgcttct taacagccaa
     4081 ggagtgaata cttacattgg tttgccgatg aatatcgtag ctttgggagt ttttgtcatc
     4141 gtatttgctt tgatttggaa aaaggaacgg acaacccttc gtttcctact aggctctcta
     4201 gctgggacta ttggtttaac cgtggctatg ttagttctca actatgttta tgctgttcct
     4261 ttgtacgcta agtttgctaa ctttgatatt ggaaaaattt tgggactttc caactaccta
     4321 atgaccatgg tattaccttt taacttgatt gaaggtgtaa tcttttccgt ttcattctgg
     4381 ttgttgtaca ttctcttgaa accaacctta aaacattatg aaagataaac aaacattttt
     4441 aatgaagggc agttttgccc ttttactttt cgttattctt ggctatatgg tcaaatttta
     4501 ccctgaaatg ttggtcaatt ttgaccaatc gattcagact gccattcgag gagacttacc
     4561 agattatttg actattcttt ttcgatccct cacacgtctg attgatattc cagtgattat
     4621 cacttgggtt gtcattatag cttttgtctt ttatcgtaag cgatggaaga tagaaagttt
     4681 cttcatgctg ggaaatctga ctttggcagg tcttttaatc gtgaccttta aaaatatcta
     4741 ccagcgccca cgaccagcta tcttacatct ggtggaggag aagggatttt ccttcccaag
     4801 tgggcattct ctggctgtaa cgctgatggt agggactttg attgttattc ttagtcagcg
     4861 gattaaagat caggtctgga gaaaaatcgt acaaatcgtc cttggcctct acctagtcag
     4921 tgtgctggta tcaagagtct atctgggagt tcattaccca tcagatgttc ttgccagtct
     4981 ctgtgtgggc ttgggagccc tgtttatcga gtttcccttt tatgataagc tccgcttcca
     5041 atggcgattt aaaggcaaac agaaatgatg gaaaagataa aaaattgtac aaatacaaat
     5101 agaaccatat gaaatatata cttgaaacat gttttggagt ttgatatatt ttaataaata
     5161 aagcaaggag gaagaaagtg tgggtatgtt attagcgaca cgcttaaaaa ataaaagaaa
     5221 ggaattaaaa ttatctcaaa aagaattagc tgaggggatt tgtgagcaag ggcagattag
     5281 ccgtatggag caaggtaaat actcacctgg gtcagaatta ctctttcaac tatctaagcg
     5341 attgaaggtg agcatggatt atttctttga agatactgag gtttctagtt tagaaaatat
     5401 tgataagttt aaagaattat ctaagaaatt tttggatgag agggaatatg aatctctcca
     5461 ttacatctat gaactggaaa aatctaaacg tgctcgtcta tctgctaaag accagattta
     5521 tttggattgg attgatacat tagttcaatt ctgttattta aatcatcaaa caggggcagt
     5581 tgcgaaactg gaaaaaatac tgttatctct gaaaaaatct gatttttact atctacaact
     5641 gggaaatacc ttggctaatt tttattttga tatggggcag gaagacacat atcaggaact
     5701 ctatcaactt ttaaaagaga acctccagtc actatctgtt catcatttgg aacagttaga
     5761 attgatgatt aaattccgat ataactattg tagatatttg tggttgaatg aacgaacatc
     5821 tgaagctata gaagaaatta cagaaacgat agctatttgt aaaagatata atagtagtta
     5881 tcgattagca gatttgtatt gtttattggg aagtataagc gagggctttg ctgaaaggga
     5941 taggatacta ggtttttatc aagtatctta ccagctttac aagcacgaag agaaccagag
     6001 aatgatgcta gaaattgaga aggaaatgaa attattggaa agtgaagatt aagcaaaaag
     6061 atttgtattc ttagataact ttaatacata ttataaaaaa aataaaaaaa tatcataaaa
     6121 attattgaca aaccaaaatt gatgtgttag aatatcacca atagttaagg aggtttagaa
     6181 gatgaaaaga tctcaagttg tcaaacgatg tatattaatt gctttattgc ttctatttct
     6241 acttaatgtg ttaagtggtt ctttatctgt aacaactaga ggagttgatc caagaccagc
     6301 atatggagtt tcgctttaaa gttgtgcata gttcttcttt tatagacgga gagtttttct
     6361 caatagtaag tgattcaaat tttgatggat gattttccat taaattaagt gattgcgaaa
     6421 actttttgaa atacattctc tttggatatt gaaagtttgt tttggatttt tttatgaagc
     6481 ttatcttagc tgttagattg gggttttatg ggatttgtcc tcaccgggaa aaaatcttaa
     6541 atctttgaag aaagaggttt ttatcttatg gttagagata catcagaaga aattgaagtt
     6601 attgacttgt cttctatgac cgtttcctac tcatctgtta tgctaggaaa ctcttggatg
     6661 acgtggaatt gatttattaa gatagattat ttggttttta ccaaaaatct gtctttttaa
     6721 tttttaaagg actaatggtg atatgaaact atatcaaata aatgatggga tacaaatttt
     6781 tgaaagtagt aatcttgaaa aaatagtaat tagaaattat aggaatggta agaaaataac
     6841 tatcgatcac caaccattat taaaaaaatt actactattc cttgaagttc ctaaacgtga
     6901 agaagaaatt ctattatatc ttccagaatt atcaaataaa acattacgaa gtgttttgac
     6961 gaattttatg agtttaaata taattcattg tcaagataca ttaataattc acaaaaaaat
     7021 aaacatattg ataataggtt tagggactac gggtggatat ctggcagatg ggttatgtcg
     7081 tagtaatatt aattcgaagc tatttctttt agataaggat cgtgtagatg agactaatgt
     7141 aggtagacag atttatttaa gagatgatat tggtcaatat aaagttgatg tatttaaaca
     7201 aaagtttagt gataaagaaa taaaggtatt caaaattttt attaatagta agaaagattt
     7261 ggaaaagatt tgcaaaaggg agggtatcga tttggttata caatgtggtg actccccttc
     7321 acctcgagaa ttaggaaaaa ttgtgaatac agtatgtgat actctccaga taccttatat
     7381 agttaacact ggctacatga gtaatgtagt tcctttgcca gaattttatt atccaaataa
     7441 tagatacaat tttaattata agcatcaatt ttcagatgaa aagttactgt tctcacaagt
     7501 tttgtctaaa gctgattata tggtggcaat tcaatcatca tttgtaatgt taatgcaaat
     7561 aaaaaatttt atatttaatg aagaacctat ttattatggt tataggggat actataattc
     7621 tgtaacatta gcatgggagg tggaaaaaat tgactaaata tttagaattg gattattctc
     7681 attcatatat tttggaaggt tttagaaaaa atgatgcgtt tattgaaaat cacaaagaat
     7741 gccttgatat gttatcagat aagatttggc gagataataa atatatgaat acagaaaaaa
     7801 acatatcatc accgacacga acaatcttat cacgctatac ttgtaatatt ttatcgtctt
     7861 tgtttattga tattagcaaa aatagcatag aaaaattgat agtgacatgt gaaaatagcg
     7921 atcttaattg gatttataat tattataaat cggtttacaa tggagtattt tgtgaattgc
     7981 gacaacttat acaacagtac tgtaaggtga aggataagta tgaaaagtgg ctttttataa
     8041 aagctattat aaatcaaggt attcgtcaaa atgagaaaga agttgttgaa ttctttttaa
     8101 aacaattgaa ggataataat caaggtattt ttgattacat caatagtttt agtttttatc
     8161 tattaaagtt ttattcaaaa gacaaatctc gcattttttt agaagagcag ctagatatag
     8221 atgatttttt gggatcagat aaagaagatt atgctaggtc tttagttttt aagaattatg
     8281 cttctctatt gcctgatact tctgaattaa aaagaaatat tatggaaaaa tgtttaagtc
     8341 aaacacctca agatacagat ttatggaaag aatggtttga aacttatgcc agtcagaaag
     8401 agattagaca aaaagcaacg gaaatattta agcatggtta ttcagatatt tcgttactaa
     8461 aattagttaa aattgagcct gatgacactg agagtttaat cagaatgatt atcttatgta
     8521 ccagtgacct aaatagtaat attgcaaggt atttgatttc atttttgagc gatgggcgat
     8581 taaaagaatt tttggagtta tttgttgaaa attttgactt tttgaatatt attgagggaa
     8641 aaactagtga gattaatttt tagaataatt agaaaagata ttatattata ttctatatta
     8701 acatttttgc tatcaatagc gatggtaagc gaagcatttt tgatgcaatt tattgttgat
     8761 tcaattaaat ttggtgaaaa gaagtatgtt ttgatttcta tttttattgt aatttttttg
     8821 attcttcaga ctttattgta ttactatcaa caatttctta cagctgtatt aagtaaaaaa
     8881 tctgcatatg agtaccgtaa attaattttt aaaaatattc agcagacttc tcttaggctt
     8941 gttacaggtg aaaaaaatga tagtattcta gcttctttga caacgcaaat cgatcaaata
     9001 gaatataatt atttttattc tgtttattgg ggtggatatt tgctttgcca attagtggta
     9061 gctatagtta tgtcgcttta tctaaatcca ttgatgtctg tattaaccat ttgcttaagt
     9121 ctccctaatt tatttgtagc acttcttttt aaaaactcct tggaacaaaa gcaagaagag
     9181 ctaattaatg agacaaattc ctcaatagca gttactcaag atttaattga gggaattact
     9241 gattggaaaa ttgcaaatag agaacctaat atatttagag tgtttgaaag caaaacattg
     9301 aagcttttag agaagcaagt gaaggtagaa aaatttcaat acattgttgt tagtttaaat
     9361 caattgtttt caaatgtttt atattttggt agttggatag taggtggatt cttgattata
     9421 cgggggcaac tttcattagg gagtttgata gcgttctctc aattattagc aagaatttct
     9481 taccctgttt acgcttcttc ggatttattg tcaaaatata ttagcggtaa aaaaattgta
     9541 gaaattcttt ctaaagaatt tatattttca gacgaaagca gaaattatcc agatgagttt
     9601 aatgttattt catttgaaca ttattttaca aacattgacg aaaaggatat gccttttgat
     9661 aaagaatttt acaaaaataa aaaatatttg ttgaaaggga aaagtggtag tgggaaaaca
     9721 acaattttaa aatcgatttt acgagagtat gatgattata gtggaattgt aaaaattaat
     9781 ggggtagatg ttagggatat aaaagagagt gttctttttg acaatatagc ttatgtttcc
     9841 caaaaacctc acttgttcag cgcaagtctt agagacaacc tgacattatt ttctgaagac
     9901 ttcactgata atgagatagt tgaggtttta aaatttgttg aattatctaa atgggctaat
     9961 aaagattgct tggatatgat gctttcaaat gatgatataa aattatcagg aggggaggtc
    10021 aaaagggttt ctttagctcg agccttattg atgaataaga atattctgtt attggatgag
    10081 ttctctgctg ggattgatta tgaaacattg ttaaaaatag agaagaaact cattgatttg
    10141 gataagatga ttatttacgt gacgcatgtg gatatagata gatccggcaa acagtttgat
    10201 gatgtcattg atttggattg tctttttata tcctcgtgac atgagagttg agtcagttga
    10261 attattttgt cactctgttt agttcttgtt ggtagtgtca ggtaatcttt gttaattttt
    10321 cagaaagtct attgaaatat cctcttggtt atatattacg aggagtaatt aatggatatt
    10381 ctcgagaatt caatacaaca atttgattct aaagttaagt atgtttcttt atttgcggaa
    10441 tcaatctttt atcagatacc atgagctatt ttgcaggtgc tatgatttct cctttgtatg
    10501 tgaggattat cggagatgat atgacagatg ctatgggggt tagacaggca actgctggtg
    10561 tagttaatat tctcagcaac cttatagggg gagttttgat tgggggtcat cagtcttcag
    10621 atgtttgtag gtttgaatgc tttgaccttt ctttttgcac tgttgggtgt ggtgtttatt
    10681 cgtacttctt tgagagatat tgaggaacag atggaggtta gtaaaagatt agccgcaaaa
    10741 tcttttggag agcatttcct ccattcaatg aagatattgt caagttttcc agccatcatc
    10801 aaattaatat tcattgcagc tatgaaccaa gtgattttaa gcattattat ccctttaacg
    10861 actttgatgt taatccatca tccatttatc ttctttgaca ctgggaaatc cattgcagca
    10921 ttgtcagtgg ttattttttc aggaacgatt gtgggaagtt ttttgagtgg aggtatccta
    10981 aaaaatattc ccataaaaat gattgtctac tttgaagaaa ttatgcatct ctgtattctc
    11041 ttttcttggt tgaccaatca tttcctcctt ttattggtag ttgtcttctt atgcgcagtt
    11101 gcagtaggaa tgatggggcc tcggattttc aaccttgtat tctcgatggt tccagaagaa
    11161 gtcatgggaa ccatccagtc agtgcttgga gtattcaatg ttgttgtacc aggaattctt
    11221 agcatgctca tcgttgcctt agcgagtgct acaaacctaa aaatcacagt gcttccactt
    11281 tttatttttg tattgactgc cttagcaatt gtgaaagcaa tgaaaataga gtaatagtag
    11341 tatgaactac tgtctctttt tgggtgggag ttcattaccc atcagacgtc cttgccagtc
    11401 tctgtgtggg cttgggagtt ttgtttatcg agtttccctt ctatgacaag ctccgcttcc
    11461 aatggcgatt taaaggcaaa cagaagtgag tatcgaattc ccttgaggag aaagaaatga
    11521 aagtcaatat agcagatctt catccgactc aactatattt atcagaaaag aagttgcaag
    11581 atattcagat gctttaccag tcggcagaaa caatccaagt cgatccaatc agtattcttg
    11641 cctttggaga ttgtttgctg attacagatg ggcatcacag ggcttatcag gctttattgg
    11701 caggtcggga tacgatttct gctgagtggg atagagatgg tggtgatgaa ctatatcatc
    11761 tctatgcgca agcttgcgag gaaagaaaga tttactctgt ttttgattta aaaaatcata
    11821 tcttacctct ttggatcggc atggtgagct ttttttgatt gaagtcaagg agaagggaga
    11881 atggtttcca attggggata ttacactatc tcaggataat ctccccattg tgattgggaa
    11941 ttccgcttac caacatcgag gacttggaaa aaagattcta agtgctttga ttgaattggc
    12001 tcgagtaaaa ggatggaaag aattgagagt caaggaaatc tacacctaca atcatgcttc
    12061 taggaggtgt ttcaagtcgc ttggatttgt ggaaaatgga gcaacagaaa aaggaaggag
    12121 ttttatattg gaattagtct aatcctgcca ctttctcccc cttaaccttt gactattccg
    12181 caaaattatc gtaaaataaa gagtaaatga taaaatgagg tcagagtctg ttcgctctga
    12241 cgatagtagt ataaatgagg agaaacgctt tggaattaga agtatttgct gggcaagaaa
    12301 aaagtgaact atctatgatt gaggtagcgc gtgctatatt agaacttcgt ggtcgcgatc
    12361 atgagatgca ttttagcgat cttgtaaacg aaattcaaaa ctaccttgga acatcaaaca
    12421 gcgatatccg cgaagctttg cctctgttct acacagagtt gaactttgac ggtagcttca
    12481 tctcacttgg ggacaacaaa tggggtcttc gttcatggta tggtgtggac gaaatcgacg
    12541 aagaaatcat cgctcttgaa gaaaatgacg acgatgaagt agcaccaaaa gctaagaaaa
    12601 aacgtgtcaa tgcctttatg gatggtgatt cagatgccat tgactacaat gcagatgatc
    12661 cagaagacga agatgcatac gaagcagatc cagctctttc atacgatgat gaaaatccag
    12721 atgatgaaaa aaatgaagtg gaagcttatg atgcagaaat caacgaaatc gctccagatg
    12781 acttgggaga agatgtggat ctcaacgaag acgacgacga gttttcagat gacgacgctg
    12841 aaaccagcga ggaataagag ttagctattg acaattatcc tatttttagg tatcatattg
    12901 tttgggcacc tcttttagag gtcggggctc cctagttctt agggagctat ttttgttttt
    12961 tcaagaagtt atcttcttgt attttatact caatgaaaat caaagagcaa gctaggaaac
    13021 tggccgtagg ctgctcaaaa cactgttttg aggttgtaga taagactgac aaagtcagga
    13081 acacatatct acggcaaggc gacgttgacg cggtttgaag agattttcga agagtattag
    13141 ttgtgaatct ggtgcagtcg tcccagatta ttcttattag tagggtcttg ttttctatat
    13201 cccctcgtag ttaacaagac cttgagcatt ttagaaagag gaatctatgt ctacgaaata
    13261 tatttttgta actggtggtg tggtatcgtc tattgggaaa gggattgtgg cagcgagtct
    13321 aggccgtctc ttgaaaaatc gtggtctcaa agtaaccatt caaaagtttg acccttatat
    13381 caatattgat ccgggaacca tgagtcctta ccagcacggg gaagtttttg tgacagatga
    13441 cggagctgag acagatttgg acttgggtca ctatgaacgt ttcatcgata tcaatctcaa
    13501 caaatattcc aacgtgacaa ctgggaaaat ttacagtgaa gttcttcgta aagaacgccg
    13561 tggagaatac cttggggcaa ctgttcaagt cattcctcat atcacagatg ctttgaaaga
    13621 aaaaatcaag cgtgccgctc taacgaccga ctctgatgtc attatcacag aggttggtgg
    13681 aacagtagga gatatcgagt ccttgccatt cctagaggct cttcgtcaga tgaaggcaga
    13741 tgtgggtgcg gataatgtca tgtatatcca tacaaccttg cttccttacc tcaaggctgc
    13801 tggtgaaatg aaaaccaaac caacccaaca ctctgtcaaa gaattgcgtg gcttgggaat
    13861 ccaaccaaat atgttggtta ttcgtacaga agagccagct ggtcaaggaa ttaaaaataa
    13921 actggcccag ttctgtgatg tggcaccaga agccgttatc gaatcgttgg atgttgaaca
    13981 cctttaccaa attccactga acttgcaggc acaagggatg gaccaaattg tttgtgatca
    14041 tttgaaatta gacgcaccag cagcggatat gacagaatgg tcagccatgg tggacaaggt
    14101 catgaacctc aagaaacaag ttaagatttc ccttgttggt aagtatgtgg agttgcaaga
    14161 tgcctatatc tcagtggtcg aagccttgaa acactctggc tatgtcaatg atgtagaagt
    14221 taaaatcaat tgggtcaatg ccaatgatgt gacagcagag aatgtagcag aactcttgtc
    14281 tgatgcggac gggatcatcg taccaggtgg ttttggtcaa cgtggtacag aagggaaaat
    14341 ccaagccatc cgctatgcgc gtgaaaatga tgttccaatg ttgggagtct gcttgggaat
    14401 gcagttgaca tgtatcgagt ttgctcgtca cgttttaggt cttgaaggtg ccaattctgc
    14461 agagcttgca ccagaaacaa aataccctat cattgatatc atgcgtgatc agattgatat
    14521 tgaggatatg ggtggaaccc ttcgtttggg actttatccg tctaagttga aacgtggctc
    14581 taaggctgct gctgcttatc acaatcaaga agtggtgcaa cgccgtcacc gtcaccgtta
    14641 tgagtttaat aatgccttcc gtgagcagtt tgaggcagca ggttttgtct tttcaggagt
    14701 ttctccagac aatcgtttgg tagaaatcgt ggaaattcct gaaaataaat tctttgtagc
    14761 ttgtcagtat caccctgaac tgtcaagccg tccaaaccga ccagaagaac tctacactgc
    14821 ctttgttact gcagcggttg agaacagcaa ttagcaaaat cagaaccttt gagaaaaatc
    14881 tcagaggttt tttgcatacg atgatattgc aatatatctg aggtaggggg cctctgtatg
    14941 tacctgctac cgttgaaatc aatagcgact ccctcttgcc ctgtgctagt gaatggattt
    15001 atcagtatat tgaaatgaaa taaaatttga acaaattaat tcggaaagcc aaatcaattt
    15061 ctagcaaagt tttaggaact ggattgtata gtgaattgaa ataagatgtg aacatctcta
    15121 tcagaaaagt caaattaatt tatagaaata ttttagcagt caagatgtac tgttatagat
    15181 tcaatacatt atactttttt aatttaatcc actatagtaa aatgaaataa gaacaggaca
    15241 aatcgatcag gacagtcaaa tcgatttcta acaatgtttt agaaatagag gtgtactatt
    15301 ctagtttcaa tatactatat atctgcagaa tactctttca gtttcattca gcctagtctt
    15361 gcttaggaaa aagtaaaaag ccatccaatt atgatggata gcttcttggt tcttagattt
    15421 gttctgcaaa aaccttttca gcaaggttca tagcgtggtc tgatacacga gtgtagtgtg
    15481 agatgatgtc gataaagttg accccagctt gtgttgaaca ttcgcctttg ttgaggcgtt
    15541 tgatgtgggt ttttctgaga acacgttcta tcttattgat tgcttcatga cgttctacaa
    15601 gactgcgtgc tttttcaata tcattgtttt ccacactatc cagagcatct ttgataaagt
    15661 cactagtttg gcggtaaact tcctctaatt ctttcaaggc ggcatcagaa aattcaacat
    15721 ttttccgttg aagatagtca gtcagattga gtagagcctc cgtgtggtct ccaatccgtt
    15781 ccaaatcacg ggaggaatca aggatattgg taagcacttc actttctttt tggctgagag
    15841 cttcgcttga aagggcaatg agataacgtg ttaattgctc atcgatggtg ttaattgctt
    15901 cttcggtttt atgccctttt tcagcaactt tttcatccaa gtcaatgatg tacttatagg
    15961 aaaggtcaaa ggctttagca gcgtagtttc ctaagtgcaa gagctctttc ttagcatttc
    16021 ctagagcgat agatggggcc tgtttgatga aatgttcatc aagatataag ggttcgtatt
    16081 tgacaacctc gtcctctcca ggaataatct tggttacaaa gtaagccaga gctccgataa
    16141 atggaaattg gacaatggtg ttggtaatat taaaggttcc gtgagcaaag gcgatggtca
    16201 tttccggtgc tagatttagc gtagcttcaa accaatgaat caggacagta aaaggaacta
    16261 gaaaaataac gcagacgact gttccgataa cgttgaaggc aacatgagct cctgctaccc
    16321 gtttagctgc aatattagcc cctaaagagg caatgatggc tgtaatggtt atcccgatat
    16381 tgtcaccaaa tagaactggc aaagctccct gtaggtcaat tagattgccg gcgtagaggt
    16441 tttgtaaaat cccaatggta gccgaagaag cttgaattag caaggtcaag ccggtaccga
    16501 caaagacacc caaaacagga ttcttactta gctcaatcat atagtcctta aagacctgta
    16561 aatccttgag tggagccatt gcgccgctca tgagattgag ggcaaaaaag ataccaccga
    16621 caccaaagag gatgcgtccg atattattga ctgtccgatt ttttgtaaaa aagagacaga
    16681 cggcaccgat aaagagcata ggtagggcat agttacctaa tttaaaaccg atgagaaagg
    16741 atgtgacagt tgtcccaata ttagcaccca tgacaatccc gatagcctga cgtaaggtta
    16801 agagaccggc actgaccagg ccgactgtga taactgttac accagaacta gactgaatta
    16861 gagcagtcat cccaatacca accagaactc caaagaaagg attactagta tatttgtcaa
    16921 tgtaaaaacg aaggcgatct ccagcagctt gttgcaaacc gtctcccatg gtcttgatgc
    16981 tatataagaa tagccccaga ccacctaaaa agtgaaataa aatttcctgc caattaatgg
    17041 acatttcttt ttcctccgaa aaataatcgc ggaatatctt ctattctatt ttaaaggata
    17101 aaagtaaatc taacaagtgt taatgtcaag tttgtaaaag aaaattataa ttgataagtg
    17161 tattattttt aagagttttt aaccttattt tagatttgtg caaacagtta ttgttttttg
    17221 tctaaaaatg ttttaggata aaaatgtgat tatcatggtt ctagagtttg ataaaaaact
    17281 acagaatata aagcgctttc ttgaaaacaa caaaatcaat cttttaggag gagaaaatga
    17341 agaatccatt ttttgaaaga cgttgtcgtt acagtattcg taagttatca gtaggagcct
    17401 gctcgctgat gattggtgct gttttatttg ctggtccagc cttggctgaa gaaactgcag
    17461 ttcctgaaaa tagcggagct aatacagagc ttgtttcagg agagagtgag cattcgacca
    17521 atgaagctga taagcagaat gaaggggaac atgctagaga aaacaagcta gaaaaggcag
    17581 aaggagtagc gatagcatct gaaactgctt cgccagcaag caatgaagct gcaactactg
    17641 aaactgcaga agcagctagc gcagctaaac cagaggaaaa agcaagtgag gtggttgcag
    17701 aaacaccatc tgcagaagca aaacctaagt ctgacaagga aacagaagca aagcccgaag
    17761 caactaacca aggggatgag tctaaaccag cagcagaagc taataagact gaaaaagaag
    17821 tccagccaga tgtccctaaa aatacagaaa aaacattaaa accaaaggaa atcaaattta
    17881 attcatggga agaattgtta aaatgggaac caggtgctcg tgaagatgat gctattaacc
    17941 gcggatctgt tgtcctcgct tcacgtcgga caggtcattt agtcaatgaa aaagctagca
    18001 aggaagcaaa agttcaagcc ttatcaaaca ccaattctaa agcaaaagac catgcttctg
    18061 ttggtggaga agagttcaag gcctatgctt ttgactattg gcaatatcta gattcaatgg
    18121 tcttctggga aggtctcgta ccaactcctg acgttattga tgcaggtcac cgtaacgggg
    18181 ttcctgtata cggtacactc ttcttcaact ggtctaatag tattgcagat caagaaagat
    18241 ttgctgaagc tttgaagcaa gacgcagatg gtagcttccc aattgcccgt aaattggtag
    18301 acatggccaa gtattatggc tatgatggct atttcatcaa ccaagaaaca actggagatt
    18361 tggttaaacc tcttggagaa aagatgcgcc agtttatgct ctatagcaag gaatatgctg
    18421 ctaaggtaaa ccatccaatc aagtattctt ggtacgatgc catgacctat aactatggac
    18481 gttaccatca agatggtttg ggagaataca actaccaatt catgcaacca gaaggagata
    18541 aggttccggc agataacttc tttgctaact ttaactggga taaggctaaa aatgattaca
    18601 ctattgcaac tgccaactgg attggtcgta atccttatga tgtatttgca ggtttggaat
    18661 tgcaacaggg tggttcctac aagacaaagg ttaagtggaa tgacatttta gacgaaaatg
    18721 ggaaattgcg cctttctctt ggtttatttg ccccagatac cattacaagt ttaggaaaaa
    18781 ctggtgaaga ttatcataaa aatgaagata tcttctttac aggttatcaa ggagacccta
    18841 ctggccaaaa accaggtgac aaagattggt atggtattgc taacctagtt gcggaccgta
    18901 cgccagcggt aggtaatact tttactactt cttttaatac aggtcatggt aaaaaatggt
    18961 tcgtagatgg taaggtttct aaggattctg agtggaatta tcgttcagta tcaggtgttc
    19021 ttccaacatg gcgctggtgg cagacttcaa caggggaaaa acttcgtgca gaatatgatt
    19081 ttacagatgc ctataatggc ggaaattccc ttaaattctc tggtgatgta gccggtaaga
    19141 cagatcagga tgtgagactt tattctacta agttagaagt aactgagaag accaaacttc
    19201 gtgttgccca caagggagga aaaggttcta aagtttatat ggcattctct acaactccag
    19261 actacaaatt cgatgatgca gatgcatgga aagagctaac cctttctgac aactggacaa
    19321 atgaagaatt tgatctcagc tcactagcag gtaaaaccat ctatgcagtc aaactatttt
    19381 tcgagcatga aggtgctgta aaagattatc agttcaacct cggacaatta actatctcgg
    19441 acaatcacca agagccacaa tcgccgacaa gcttttctgt agtgaaacaa tctcttaaaa
    19501 atgcccaaga agcggaagca gttgtgcaat ttaaaggcaa caaggatgca gatttctatg
    19561 aagtttatga aaaagatgga gacagctgga aattactaac tggctcatct tctacaacta
    19621 tttatctacc aaaagttagc cgctcagcaa gtgctcaggg tacaactcaa gaactgaagg
    19681 ttgtagcagt cggtaaaaat ggagttcgtt cagaagctgc aaccacaacc tttgattggg
    19741 gtatgactgt aaaagatacc agcctaccaa aaccactagc tgaaaatatc gttccaggtg
    19801 caacagttat tgatagtact ttccctaaga ctgaaggtgg agaaggtatt gaaggtatgt
    19861 tgaacggtac cattactagc ttgtcagata aatggtcttc agctcagttg agtggtagtg
    19921 tggatattcg tttgaccaag ccacgtaccg ttgttagatg ggtcatggat catgcaggag
    19981 ctggtggtga gtctgttaac gatggcttga tgaacactaa agactttgac ctttattata
    20041 aagatgcaga tggtgagtgg aagctagcta aggaagtccg tggtaacaaa gcacacgtga
    20101 cagatatcac tcttgataaa ccaatcactg ctcaagactg gcgcttgaat gttgtcactt
    20161 ctgacaatgg aactccatgg aaggctattc gtatctataa ctggaaaatg tatgaaaagc
    20221 ttgatactga gagtgtcaat attccgatgg ccaaggctgc agcccgttct ctaggcaata
    20281 acaaggtaca agttggcttt gcagatgtac cggctggagc aactattacc gtttatgata
    20341 atccaaattc tcaaactccg ctcgcaacct tgaagagcga agttggagga gacctagcaa
    20401 gtgcaccatt ggatttgaca aatcaatctg gtcttcttta ttatcgtacc cagttgccag
    20461 gcaaggaaat tagtaatgtc ctagcagttt ccgttccaaa agatgacaga agaatcaagt
    20521 cagtcagcct agaaacagga cctaagaaaa caagctacgc cgaaggggag gatttggacc
    20581 ttagaggtgg tgttcttcga gttcagtatg aaggaggaac tgaggacgaa ctcattcgcc
    20641 taactcacgc aggtgtatca gtatcaggtt ttgatacgca tcataaggga gaacagaatc
    20701 ttactctcca atatttggga caaccagtaa atgctaattt gtcagtgact gtcactggcc
    20761 aagatgaagc aagtccgaaa actattttgg gaattgaagt aagtcaggaa ccgaaaaaag
    20821 attacctagt tggtgatagc ttagacttgt ctgaaggacg ctttgcagtg gcttatagca
    20881 atgacaccat ggaagaacat tcctttactg atgagggagt tgaaatttct ggttacgatg
    20941 ctcaaaagac tggtcgtcaa accttgacgc ttcgttacca aggtcatgaa gtcaactttg
    21001 atgttttggt atctccaaaa gcagcattga acgatgagta cctcaaacaa aaattagcag
    21061 aggttgaagc tgctaagaac aaggtggtct ataactttgc ttcaccagaa gtaaaagaag
    21121 ctttcttgaa agcaattgaa gcggccgaac aagtgttgaa agaccatgaa actagcaccc
    21181 aagatcaagt caatgaccga cttaataaat tgacagaagc tcataaagct ctgaatggtc
    21241 aagagaaatt taaggaagaa aagacagagc ttgatcgttt aacaggtgag gttcaagaac
    21301 tcttggctgc caaaccaaac catccttcag gttctgccct agctccgctt cttgagaaaa
    21361 acaaggcctt ggttgaaaaa gtagatttga gtccagaaga gcttgcaaca gcgaaacaga
    21421 gtctaaaaga tctggttgct ttattgaaag aagacaagcc agcagtcttt tctgatagta
    21481 aaacaggtgt tgaagtacac ttctcaaata aagagaagac tgtcatcaag ggtttgaaag
    21541 tagagcgtgt tcaagcaagt gctgaagaga agaaatactt tgctggagaa gatgctcatg
    21601 tctttgaaat agaaggtttg gatgaaaaag gtcaagatgt tgatctctct tacgcttcta
    21661 ttgtgaaaat cccaattgaa aaagataaga aagttaagaa agtatttttc ttacctgaag
    21721 gcaaagaggc agtagaattg gcttttgaac aaacggatag tcatgttatc tttacagcac
    21781 cacactttac tcattatgcc tttgtttatg aatctgctga aaaaccacaa cctgctaaac
    21841 cagcaccaca aaacaaagtc cttccaaaac ctacttatca accggcttct gatcaacaaa
    21901 aggctcctaa attggaagtt caagaggaaa aggttgcctt tcatcgtcaa gagcatgaaa
    21961 atgctgagat gctagttggg gaacaacgag tcatcataca gggacgagat ggactgttaa
    22021 gacatgtctt tgaagttgat gaaaacggtc agcgtcgtct tcgttcaaca gaagtcatcc
    22081 aagaagcgat tccagaaatt gttgaaattg gaacaaaagt aaaaacagta ccagcagtag
    22141 tagctacaca ggaaaaacca gctcaaaata cagcagttaa atcagaagaa gcaagcaaac
    22201 aattgccaaa tacaggaaca gctgatgcta atgaagccct aatagcagtc ttagccagcc
    22261 ttggtcttgc tagtttagcc ttgaccttga gacggaaaag agaagataaa gattaaatat
    22321 cgaaaaatct tgtgaaatct ttccttatat ttccaaagtg tgatataata gtttcgaata
    22381 aaataaataa aggagttttt gtaacatggc aaaacttact gttaaagacg ttgacttgaa
    22441 aggtaaaaaa gtcctcgttc gtgttgactt caacgtacca ttgaaagatg gcgtaatcac
    22501 taacgataac cgtatcacag cagctcttcc aactattaag tacatcatcg aacaaggtgg
    22561 acgtgcaatt cttttctctc accttggacg tgtgaaagaa gaagctgata aagctggcaa
    22621 atcacttgct cctgtagcag ctgacttggc agcaaaactt ggtcaagatg ttgttttccc
    22681 aggtgtcact cgtggtgctg aattggaagc ggcaatcaac gctcttgaag atggacaagt
    22741 tctcttggtt gaaaacactc gttacgaaga tgttgacggc aagaaagaat ctaaaaacga
    22801 tcctgaactt ggtaaatact gggcatcact tggagatggt atcttcgtaa acgatgcatt
    22861 cggtacagct caccgtgcac acgcatctaa cgttggtatc tcagcaaacg ttgaaaaagc
    22921 agttgctggt ttccttcttg aaaacgaaat tgcctacatc caagaagcag ttgaaactcc
    22981 agaacgtcca ttcgtggcta tccttggtgg ttcaaaagtt tcagacaaga tcggtgttat
    23041 cgaaaacttg cttgaaaaag ctgataaagt ccttatcggt ggtgggatga cttacacatt
    23101 ctacaaagca caaggtatcg aaatcggtaa ctcacttgta gaagaagaca aattggatgt
    23161 tgcgaaagct cttcttgaaa aagcaaatgg taaattgatc ttgccagttg actcaaaaga
    23221 agctaacgca tttgctggtt acactgaagt gcgtgacact gaaggtgaag cagtttctga
    23281 aggcttcctt ggtcttgaca tcggtccaaa atctatcgcc aaatttgacg aagctttgac
    23341 tggtgccaaa acagttgtat ggaacggacc tatgggtgta tttgaaaacc cagatttcca
    23401 agctggtaca atcggtgtga tggacgctat cgtgaaacaa ccaggagtta aatcaatcat
    23461 cggtggtggt gactcagctg ccgcagcgat taaccttggc cgtgcagaca agttctcatg
    23521 gattagtacg ggtggtggag catcaatgga acttcttgaa ggtaaggttc ttccaggact
    23581 tgcagccttg acagaaaaat aagattttat aaacaaatca aagaagagag ggatgaaagt
    23641 tcctcttttc ttttgcttaa aataaaaacg cttcctctca actattactc ataaaaatca
    23701 ccgatttatg ataaaatgga aatagaaagt tgagattatg agttatttta aaaaatataa
    23761 attcgataaa tcccagttca aacttggtat gcgaaccttt aaaacaggta ttgctgtttt
    23821 tctagttctc ttgatttttg gcttttttgg ctggaaaggt cttcaaattg gtgctttgac
    23881 agccgttttt agcctgaggg agagttttga tgagagtgtt cattttggga cttcgcgtat
    23941 tctaggaaat agtatcggtg gactctatgc cttggtcttc ttcttattaa atactttttt
    24001 ccacgaagcc ttttgggtga ccttggtagt tgttccaatc tgcaccatgt taaccattat
    24061 gacaaatgta gccatgaata acaaagcagg ggttattggt ggtgtagcag ctatgttaat
    24121 cattacccta tcaattccaa gtggtgagac aattttgtac gtgtttgtgc gtgtattaga
    24181 aacgtttatg ggagtttttg tcgcaattat cgtaaattac gatattgatc gtattcgtct
    24241 ctttttagag aaaaaagaaa aataatgtta cattttataa cattatcaat tgacgtttgt
    24301 ctttttttag actataatag acagaaagaa ggaaattgta aatgaaggaa aaagaatttc
    24361 gccgaaatat ggctgttttt cctatcggca gtgttatgaa gttgaccgat ttatcggcgc
    24421 gtcagattcg ttattatgaa gatcaagagt tgatcaagcc cgatcgaaac gaaggaaatc
    24481 gtcgcatgta ttccttgaat gacatggatc gtctgcttga aatcaaagat tatatctctg
    24541 aaggttataa tatcgctgcc attaagaaaa aatatgctga acgtgaagcg aaatccaaga
    24601 aagcggttag tcagactgaa gtacgtcgtg cacttcacaa tgaactcctc caacaggggc
    24661 gttttgcttc agtacagtca ccttttggtc gcggttaggc aaccgcaagt agtcatagat
    24721 taaggagaaa acttatgcca atcacagctg cagatattcg tcgtgaagtc aaggaaaaaa
    24781 atgttacctt tattcgtctt atgttctcag atattttggg aaccatgaaa aacgtcgaaa
    24841 ttcctgctac agatgaacag ttagataagg tcttgtcgaa caaggttatg tttgatggat
    24901 cttctattga aggttttgta cgtatcaatg agtcggatat gtacttgtac ccggacttgg
    24961 atacatggac agtcttccct tggggagatg aaaatggaag tgttgcaggt ctgatctgtg
    25021 atgtctatac aacagaaggt gaaccatttg cgggtgaccc tcgtggtaat ttgaaacgag
    25081 ctcttcgtca catggaagaa gttggattca aatccttcaa ccttggtcca gagccagaat
    25141 tcttcctatt taagttggat gaaaatgggg acccaacact tgaagtgaat gacaagggtg
    25201 gctactttga tttggcacct actgaccttg cggacaacac acgtcgtgag attgtgaatg
    25261 tcttgaccaa aatgggattt gaagtagaag cgagtcacca cgaggttgcg gttggacagc
    25321 atgagattga ctttaagtac gatgaagttc tccgtgcttg tgataagatt caaatcttta
    25381 agcttgttgt taaaaccatt gctcgcaaac acggacttta cgcaacattt atggcgaagc
    25441 caaaatttgg tattgctgga tcaggtatgc actgtaatat gtccttgttt gatgcagaag
    25501 gaaataacgc cttctttgat ccaaatgatc caaaaggaat gcagttgtca gaaacagctt
    25561 accatttcct aggcggtttg atcaagcatg cttacaacta tactgccatc atgaacccaa
    25621 cagttaactc atacaaacgt ttggttccag gttatgaagc gcctgtttac attgcttggg
    25681 ctggtcgtaa ccgttcgcca cttgtgcgcg tacctgcttc acgtggtatg ggaactcgtc
    25741 ttgagttgcg ttcagtggat ccaatggcga acccttacat tgctatggct gttcttttgg
    25801 aagttggttt gtatggtatt gaaaataaaa tcgaagcacc agctcctatc gaagaaaata
    25861 tctacatcat gacagcagaa gagcgcaagg aagctggtat tacagacctt ccatcaactc
    25921 ttcacaacgc tttgaaagct ttgacagaag atgaagtggt taaagctgct ctcggagatc
    25981 acatctacac tagcttcctt gaagccaaac gaatcgaatg ggcaagttat gcaaccttcg
    26041 tttcacaatg ggaaattgat aattatttag acctttacta atactaatat agaagaaaga
    26101 ttgcctgtgg gtaaacagtc acacagcagt ctaagccatc aaatacctat aacccttaaa
    26161 atagcgattt cggtcgctat ttatttttcg aaaaatcctc ttgactcttt tgcgaattag
    26221 atttatcatc agacgtgtag aagaaaatca aggagtcact atggaaaaat tcaatttcaa
    26281 aaacaatatc gggcaagaaa acaagttact tcaaatcgaa atctacaagt ttactaactt
    26341 ttgcaagctt caaaattaca catctgtaaa tattttttcg aaagatatat ttgaagccat
    26401 agtaaattga gactagaata gtacactaca tctgctaaaa atttctagaa attaatttaa
    26461 ctttcctaat cgatttgttt acatcttatt tcaatctact atattatctc aataaatgat
    26521 gatggcgact gttttgtttg tgcttgtcga tttttgaatc ctgatcgagc ggaagaatat
    26581 ttctgccgag gttgtcaagg ggaaaatcct gaagatattg aattttatga tgaacaatta
    26641 caggcagaaa aggtggaggc tttgaatatt cgattggaag taaaaaattg aattatctac
    26701 aatctcatca acaataaacc tatttcaacc ccattatcta taggcgtatt tttacgcctt
    26761 tttatatact tgaagcacat aagaaacatt atgggaagtt tgctgatgga agtactcaag
    26821 aaattgatgt tccttatgat attcctgata cttgggagtg ggtgaggata aaatcaattt
    26881 attggaattt tgggcaaaat aagccagaga aatcctttag gtatatagat acgtctagta
    26941 ttgatagaaa aaagaacata atcaactaca aaaatctaca atatctttca cctgaacaag
    27001 cgccttcccg tgccagaaaa ttagtttcgc agaatagtgt cttattttca acagttagac
    27061 catatctaaa aaatattgct gtagttagag aacttaaaga gtatttgata gctagtacag
    27121 catttattgt tttggatact ttacttaacg aaacatattt gaaatattat ttattatcag
    27181 ataattttat caatcgtgtt aataataaat ctactggaac aagttatcct gcaatcaatg
    27241 attataattt taatctatta ttaatt
//
LOCUS       DAVBIC010000030        25904 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.030, whole genome shotgun sequence.
ACCESSION   DAVBIC010000030 DAVBIC010000000
VERSION     DAVBIC010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25904)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25904)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25904
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.030"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            1..283
                     /locus_tag="VQ664_001231"
                     /pseudo
     CDS             1..283
                     /locus_tag="VQ664_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
     gene            201..629
                     /locus_tag="VQ664_001232"
     CDS             201..629
                     /locus_tag="VQ664_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET2789393.1"
                     /translation="MSKSTSKRYYQVAIPFTRLFCLVLVSIDYINCLSETADKNWHKS
                     DRIFVTNTGKTVHSSILSKSLQRANERLKKPIPKHLSPHIFIHITISILSENKIPLKT
                     ITDRVGHPDSEVTNSIYTHVTKNMKDEAINVLDKVMKKIF"
     gene            complement(1121..1531)
                     /locus_tag="VQ664_001233"
     CDS             complement(1121..1531)
                     /locus_tag="VQ664_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001124848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789394.1"
                     /translation="MPKKKIERISVIHREKILWLKWYFMRDKEKPKYSVLECKMFDAA
                     KNKDMLAYKKYATIKQITDIRVQTSEDDILTAIKEVYVYNHMNVIGACQRILFVSQSP
                     AYNKLNKWFETYSDLYFSIIPLPNMGAYHELVDS"
     gene            complement(1549..1926)
                     /locus_tag="VQ664_001234"
     CDS             complement(1549..1926)
                     /locus_tag="VQ664_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789395.1"
                     /translation="MRKYLKEIKELQELKELLSSRNTPEVIIVEGNDDLGEFFQVDGE
                     LFSDIELLENLKKWREWEVQVIVDDWCNRGLNEYETGILYFPKHEDKMDYIRFNKGLE
                     PLYHALDEPYTTISKSEWLKLLD"
     gene            complement(1868..2296)
                     /locus_tag="VQ664_001235"
     CDS             complement(1868..2296)
                     /locus_tag="VQ664_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000918209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HET2789396.1"
                     /translation="MAGNENDGLTSKQIKFIDAMLTEPTIDKACQKAGVSRATGHKYL
                     KVAAVKKTLRLKQDEMMDKTTQMLYLASSNAVSVLNDIMMDAKINPFIRTQAAKTILE
                     QSYKTHEIFGVVRQIEELRLEIEEVSKGDQRVTRTQGIIK"
     gene            complement(2340..2945)
                     /locus_tag="VQ664_001236"
     CDS             complement(2340..2945)
                     /locus_tag="VQ664_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789397.1"
                     /translation="MTFTTIKDDIKAFGKKKHGYMTGYIAKQEELHKQLQNGMIGEKY
                     AKDQLEAYKLEGDTYSRDTYNKIHAEIEKQHDLELEALKEKELSVTADDVAELTLLAS
                     MKMTKDELLGYFEKYKNKPLAIKKLWSIAEQYPEIAINLELFNAEQALESLILFFKRQ
                     LSYCHYSLLINGDKIQAVTTEMVVNSDAPELDRRLDEYLNK"
     gene            complement(3035..3208)
                     /locus_tag="VQ664_001237"
     CDS             complement(3035..3208)
                     /locus_tag="VQ664_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789398.1"
                     /translation="MTENKDNKLLEMMEKGFVLYSKNGIIKYIEIPDHGSIKLKAQDG
                     QLVYKEVTTGEQC"
     gene            complement(3807..4703)
                     /locus_tag="VQ664_001238"
     CDS             complement(3807..4703)
                     /locus_tag="VQ664_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HET2789399.1"
                     /translation="MKSLQSSLGNIETFKLDELCPKHEIQLTQIKGERHVVVGWNENG
                     EVIKEVRCIPPYCEQCQEEQKKQDEEDAIADNLNAKLYLQTYNVLMSNKSYVADEFKT
                     KTFDDFNAVTSEEKRFLEFAKGQVQKYLDGMRGNTLITGGTGIGKTLLSVAIAKGINE
                     GYKTKGEPKSVLFVSLTEMIKQIKEGWNYGKGATLTEFEATELMKSVDYLIIDDLGAK
                     NAVIKPKSDWEQDLLFDVLNNRENTIFNTNLDSDELKIVYNERNYSRILKGLEGNTFK
                     AFTIKDKRYSINQLKNKVKQLK"
     gene            complement(4715..5524)
                     /locus_tag="VQ664_001239"
     CDS             complement(4715..5524)
                     /locus_tag="VQ664_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HET2789400.1"
                     /translation="MAKTKVYFWLKIDKKFFDNIFIKRLKTVPGGYTMTVIYIRLMLE
                     SLESDCILYYEGYFNNLKEELALKLDVSEDDIDMTMAYFTKCGLIQIDEDKNAELPQA
                     KAMVMSETNWASYKREQRKKGKLEEVQPSLTFSNSCPTEIEKELEIEVDKEQSPTPST
                     INQDFVNLYKSFEAETGKALSPLQIQELQYMLEDFSPELIHEALKEAVSQGKANFAYI
                     KAILNRWKQDNLLTVELVRNSRAAREAKKQQTNQLEPTSYEDWIPTQEKPF"
     gene            complement(5599..5814)
                     /locus_tag="VQ664_001240"
     CDS             complement(5599..5814)
                     /locus_tag="VQ664_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789401.1"
                     /translation="MNELDISNTQAVFVTVILIGLLLYLNHRDRKKSAQLERENQQTI
                     ETPSEDLNPDYGRYIQLAGVDVWGRIE"
     gene            complement(5816..6016)
                     /locus_tag="VQ664_001241"
     CDS             complement(5816..6016)
                     /locus_tag="VQ664_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789402.1"
                     /translation="MTLDLDNMTQAEFDEAMAEIQLQSPNIFQLISDFVNKKVTSVEI
                     DDLLNMKRAEQVAYIKNYKARA"
     gene            complement(6013..6204)
                     /locus_tag="VQ664_001242"
                     /pseudo
     CDS             complement(6013..6204)
                     /locus_tag="VQ664_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841301.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(6193..6483)
                     /locus_tag="VQ664_001243"
                     /pseudo
     CDS             complement(6193..6483)
                     /locus_tag="VQ664_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424675.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
     gene            complement(6653..6805)
                     /locus_tag="VQ664_001244"
     CDS             complement(6653..6805)
                     /locus_tag="VQ664_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789403.1"
                     /translation="MKIVTFKPTKQIDGGFYLPGIDILFVSDKADAKSTEDVILFISR
                     NGLNKS"
     gene            complement(6816..7082)
                     /locus_tag="VQ664_001245"
     CDS             complement(6816..7082)
                     /locus_tag="VQ664_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789404.1"
                     /translation="MEILSKEIQLQGLQLLKQTLETLVELEKQRSSKLDLISRKELMD
                     LLGISATTLDNWEDLALKRYQTPMDGAKKVFYRLSDVYLFLAIK"
     gene            complement(7293..7475)
                     /locus_tag="VQ664_001246"
     CDS             complement(7293..7475)
                     /locus_tag="VQ664_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET2789405.1"
                     /translation="MLITLSLAEKVRIKRARLQLTKKAVSEQLGIKSQTLTKVENGNY
                     DASKRIYESVMTWLVE"
     gene            7537..8040
                     /locus_tag="VQ664_001247"
     CDS             7537..8040
                     /locus_tag="VQ664_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2789406.1"
                     /translation="MYKMNRIKQLRKENNLTQRELANETKIPYRTIQRWENGETDIKS
                     DAAQVLADYFGVSIPHLLGYSDLIADTDSDIKAMAYSHLLTFVDEKQIKEFEKEFIRA
                     NDNSDTFGDLGSGEKALEKYYQALCYLVPPFRDILARYSFLSLDEKKSVYNIIVGLSN
                     NLSKENK"
     gene            8114..9277
                     /locus_tag="VQ664_001248"
     CDS             8114..9277
                     /locus_tag="VQ664_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HET2789407.1"
                     /translation="MNIIEKIKKNGQRVYYASVYLGVDQLTGKKARTTVTATTKKGVK
                     VKARDAINTFAANGYTVKDKPTITTYNELVKVWWDSYKNTVKPNTRQSMDGLVRVHLL
                     PVFGDYKLSKLTTPILQQQVNKWADKANKGEKGAFANYSLLHNMNKRILKYGVAIQVI
                     QYNPANDVIVPRKQQKEKAAVKYLDNKELKQFLDYLDTLNQSNYENLFDVVLYKTLLA
                     TGCRISEALALEWSDIDLESGVISINKTLNRYQEINSPKSSAGYRDIPIDKATLLLLK
                     QYKNRQQIQSWKLGRSETVVFSVFTEKYAYACNLRKRLNKHFDAAGVTNVSFHGFRHT
                     HTTMMLYAQASPKDVQYRLGHSNLMITENTYWHTNQENAKKAVSNYETAISNL"
     gene            complement(9431..10735)
                     /gene="eno"
                     /locus_tag="VQ664_001249"
     CDS             complement(9431..10735)
                     /gene="eno"
                     /locus_tag="VQ664_001249"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HET2789408.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            10899..11345
                     /locus_tag="VQ664_001250"
     CDS             10899..11345
                     /locus_tag="VQ664_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HET2789409.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAEPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPFGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            complement(11342..12457)
                     /locus_tag="VQ664_001251"
     CDS             complement(11342..12457)
                     /locus_tag="VQ664_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HET2789410.1"
                     /translation="MKIVIAPDSFKESLTAQQVAEAIKRGFQQSIADVECLLCPVGDG
                     GEGTVDAIRHSLDLKEKWIQVTDPFGQKEAMRYFQKGELALFEVADLVGLGKIPLEKR
                     NPLQIQTCGIGELILHLISKGIKDIYIDVGGTASNDGGLGIAAGLGYQFYDRDGNVLP
                     ASGQSLLNLASVSTENCYKIPEGVQIHILADVVSPLCGHQGATYTFGNQKGRHPTMFA
                     VVDQAIQDFYEKFSPATLEIKGAGAGGGLAGGLCAFAQASIVSGIDTCLDLINFDKKV
                     SDADLVVVGEGRLDSQSFAGKAPIGVAKRTPVGVPVIAICGSLAEDLPPLPFENIQAV
                     FSILEKSEPLEDSLKNASLYLERTAANIGHLLNMCKI"
     gene            complement(12466..12795)
                     /locus_tag="VQ664_001252"
     CDS             complement(12466..12795)
                     /locus_tag="VQ664_001252"
                     /inference="COORDINATES: protein motif:HMM:NF019887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HET2789411.1"
                     /translation="MERLAKSLGIAYFTANQLEVKEGLLTGKLVGQIISPQVKKETLE
                     KWRKKLKLSKERTVAIGDGGNNLLMLKSAELGIAFCSKEMLKKEIPHHVDKRDFLEVL
                     PLIDCLE"
     gene            complement(12749..13111)
                     /locus_tag="VQ664_001253"
     CDS             complement(12749..13111)
                     /locus_tag="VQ664_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family phosphatase"
                     /protein_id="HET2789412.1"
                     /translation="MSQVKGLCVLDVDGTLILEEVIDLLGREAGHEAEISQITSRAMR
                     GELVFESSLRKRVSLLEGLPILVFDNVFNSIHLSLNVPEFISILQKNGILVGLVSGGF
                     TPIVGEISKIPWYCLFHC"
     gene            complement(13170..14603)
                     /gene="glgA"
                     /locus_tag="VQ664_001254"
     CDS             complement(13170..14603)
                     /gene="glgA"
                     /locus_tag="VQ664_001254"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HET2789413.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGNQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYRWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGFERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWFAQIYPDKLSTNITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            complement(14600..15739)
                     /gene="glgD"
                     /locus_tag="VQ664_001255"
     CDS             complement(14600..15739)
                     /gene="glgD"
                     /locus_tag="VQ664_001255"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HET2789414.1"
                     /translation="MKIDKYSAILGNTVGFHNMSTLTDHRPVASLPFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTFLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAETFNMSTDIFVVDTPWLIEHLEEEAKKEHPEK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVRTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GEGAQVEYAILDKGVEVEPGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            complement(15729..16871)
                     /locus_tag="VQ664_001256"
     CDS             complement(15729..16871)
                     /locus_tag="VQ664_001256"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HET2789415.1"
                     /translation="MKNEMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGINSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLESGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGTVKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVATDED"
     gene            complement(16861..18789)
                     /gene="glgB"
                     /locus_tag="VQ664_001257"
     CDS             complement(16861..18789)
                     /gene="glgB"
                     /locus_tag="VQ664_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HET2789416.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEYGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRNDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAIVTELPDKKWRDGLWLARRKRWGFAERPVNIYEVHAGSWKRNPDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDIYHLDGIRVDAVSNMLYLDYDDAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPDVMMIAEESSSATKITGMKEIGGLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFTSQLNQFYKDH
                     RCLWEIDTSYDGIEVIDADNRDQSVLSFIRKGKKGEMLVCIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTNKNQKGVENEK"
     gene            complement(19271..20695)
                     /locus_tag="VQ664_001258"
     CDS             complement(19271..20695)
                     /locus_tag="VQ664_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HET2789417.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAIERAAYLHKTAAILERDKEKIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEAASKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMLKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVADKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     GLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
     gene            complement(21239..23518)
                     /gene="pulA"
                     /locus_tag="VQ664_001259"
     CDS             complement(21239..23518)
                     /gene="pulA"
                     /locus_tag="VQ664_001259"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HET2789418.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKTYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLAPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGSYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTGAFSY
                     SSYDEIYHHVFVHSAIEHSGCLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(23630..25588)
                     /gene="ligA"
                     /locus_tag="VQ664_001260"
     CDS             complement(23630..25588)
                     /gene="ligA"
                     /locus_tag="VQ664_001260"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HET2789419.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVSDSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQVRQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KASQLLLQYFHSIENLSQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSVSKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(25681..>25904)
                     /locus_tag="VQ664_001261"
     CDS             complement(25681..>25904)
                     /locus_tag="VQ664_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET2789420.1"
                     /translation="FFTQVQTKVESEFLGRVLSTIFTLAILFMPIAKGFMTVLPSVHL
                     SSFLIIGSGVIILSCISFIYVRTHFEKLI"
BASE COUNT         7685 a         5492 c         4450 g         8277 t
ORIGIN      
        1 gatgacgagc gacttttttg aagcttggtt tcagaagttt ctcttaccaa cattaaccac
       61 accatcggtt attattatgg ataatgtaag attccataga atggggaagc tagaactctt
      121 gtgtgaatag tttgggcata aacttttacc tcttcctccc tactcacctg agtacaatcc
      181 tattgagaaa acatgggctc atatcaaaaa gcacctcaaa aaggtattac caagttgcaa
      241 taccttttac gaggctcttt tgtcttgttc ttgtttcaat tgactatata aattgtctaa
      301 gcgaaacagc cgataagaat tggcacaaaa gcgaccgtat ttttgttacc aatacaggaa
      361 aaacagttca tagttctatc ttgagcaagt ctctccagcg agcaaacgaa cgccttaaaa
      421 aaccaattcc caaacatctg tcccctcaca tcttcataca catcactatt agcatcttat
      481 cagaaaataa aattccttta aaaacaatca cggacagggt tggtcatccc gactctgaag
      541 tcactaattc catctacacc cacgtcacaa agaacatgaa agatgaagca atcaatgtac
      601 tggataaagt tatgaaaaag attttttaaa aagttttgtc ccttttttgc cctctaaata
      661 caaaaatagc ccttcggata aaatccgagg ggctagaaac gttgttaaat caacggccga
      721 acttttgaat ttcatggttc gggataaaat agttcactga actattttat tttttaaggt
      781 tatcataata tcaaatagtt caattaaata cgctaaatta ctaatatact ttttaccttt
      841 ttcattctaa aatgtaaagt acaaacaatt acaatatact agagggggag taaaaaaggt
      901 aataaaattg acgagttcag caggcaaggg aaatagcact tttcatggtg ttattttttt
      961 aattcagcaa tggagtagcc gcttaattga tagaaacaaa aagcacctag tttcctagat
     1021 gctagcacaa tagcccggat tcgaaccgga atctcctcaa ttaaggtgca atccctatat
     1081 actactcatt gtgctttggt tcattatatc atacaatcaa ctagctatct accaactcat
     1141 gatacgctcc catattcggt aatggaataa tactaaaata caaatctgag taagtttcaa
     1201 accatttatt cagcttgtta taggctggcg actgactaac aaataatatc cgttgacaag
     1261 ctccgataac attcatgtga ttatacacat agacctcttt aatggccgtt aaaatatcgt
     1321 cttcacttgt ctgtacccta atatctgtta tctgcttaat cgtagcgtat tttttataag
     1381 ctagcatatc tttattttta gcagcatcaa acattttaca ctcaagaaca ctatacttag
     1441 gtttttcttt atctctcatg aaataccact tgagccataa aattttttct ctgtgaatta
     1501 ctgaaatacg ttcgattttt ttctttggca tgattacctc ctaaattatt aatctaatag
     1561 ctttaaccac tcactttttg agattgttgt ataaggttca tctagcgcgt gatataaagg
     1621 ttctaaacct ttgttaaatc ggatatagtc cattttatcc tcatgctttg gaaaatataa
     1681 gattcctgtt tcatattcat ttagaccacg gttacaccaa tcatcaacga taacctgcac
     1741 ttcccattca cgccactttt taaggttttc taaaagttca atatcactaa ataactcacc
     1801 atcaacttgg aaaaattctc ccagatcatc gttaccctcg acgatgataa cttcaggcgt
     1861 atttctacta cttaataatt ccttgagttc ttgtaactct ttgatctcct ttagatactt
     1921 cctcaatttc taacctcaat tcttcaattt gtcttactac tccaaaaatt tcatgagttt
     1981 tatatgattg ttcaagtata gtttttgctg cttgagttct tataaaaggg ttaattttgg
     2041 catccatcat aatatcattg agtacagaaa cagcattgga tgaggctaga tatagcatct
     2101 gtgtagtttt atccatcatc tcatcttgtt ttagtctcaa tgtcttttta acagctgcaa
     2161 cttttagata cttatgccct gttgcccttg acacccctgc tttttggcac gctttatcta
     2221 tcgttggctc agtaagcatg gcatctatga attttatttg tttagatgta aggccatcat
     2281 tttcatttcc tgccatctat tacctcctcg ttatcaaaat aaaggggttg ctagcccctc
     2341 tatttgttta aatactcatc caaacgacgg tcaagctcag gggcatctga atttactacc
     2401 atttcagttg ttacagcttg gattttatcg ccgttgataa gcaaactgta atgacaatat
     2461 gaaagttgcc gcttaaagaa taagattaga ctttctagcg cctgctctgc attgaataat
     2521 tccaagttga tagcaatttc tggatattgt tcagcaattg accaaagttt tttaatagca
     2581 agaggtttgt tcttgtattt ttcaaaataa cctagcaatt catcctttgt catcttcata
     2641 ctagctaaca aggtcagctc tgccacgtca tcagctgtta cgctgagttc tttttctttt
     2701 aatgcctcta gctctagatc atgctgtttt tcaatttctg catgaatttt attataggtg
     2761 tccctagaat aagtgtcccc ctctaactta taagcctcta gctggtcttt agcgtatttt
     2821 tcgcctatca taccattttg taactgttta tgtaattcct cttgtttagc aatgtagcca
     2881 gtcatgtacc catgcttttt cttgccaaaa gccttaatat catccttgat tgttgtaaat
     2941 gtcatgttat cctccttacg aaaaaataaa agaggtatga caaaagagcg ttaaactcaa
     3001 ttatcatacc tctggttttt ccagtcagta tttattaaca ttgttctcca gtggtcactt
     3061 ccttataaac taactgccca tcttgagctt ttagcttaat gctaccatga tctggaattt
     3121 caatgtactt tattatacca ttttttgagt ataaaacaaa gcctttctcc atcatttcta
     3181 ataatttatt atccttgttt tcagtcatga atttctcctt tatttcaagt gtcccaacgg
     3241 gtacggttgt aagctgagac attttagggc tatctttgag cgacaaaaat gtcgaaaagt
     3301 cttcagttcc tgtataaccg ttattagttt tgtttgctac tcatttttga gtcacaaatc
     3361 tgttaagcaa aaatgagtaa tagctcgtaa gataagtaaa tctaatactt gtattcctaa
     3421 agcgttgata taactgatat tttcaactat ccaacgctct ttactaccct ttttagtgtg
     3481 ctttagctca tttttgagct tttttgagct tttttgagtt ccattttggg aatgcaaagc
     3541 aggcgcgcac cgtgcatgct tttttcttgc tcatagcctc accctcagaa gtttgccgac
     3601 cgagagcgtg gggcttttta tttttgtata attaaaaaca gctgcacaat ttttgtacag
     3661 ctacgaccga ggcaggggcg acctgccgta ctttacacta gataatatca tctaggtagt
     3721 ccaactgtat tttatcatat taaaggctac attacaattt ctcaccctgt gaagagtgtc
     3781 tatttttgtt taggtttgta agtcgattac ttcaactgct ttaccttatt ttttaactga
     3841 ttaattgagt atcgcttatc tttgattgtg aaagccttaa aagtgttacc ctcaagacct
     3901 tttagaatac ggctataatt ccgctcgttg tatactatct tgagttcatc gctatcaaga
     3961 tttgtattaa atatagtatt ttctcgatta ttcagtacat caaaaagtaa atcctgctcc
     4021 caatcgctct taggtttaat aacagcattt tttgcaccta aatcatcaat aattaagtaa
     4081 tcaacagact tcatgagttc agtagcttca aactctgtaa gtgttgcacc tttaccataa
     4141 ttccacccct ctttaatttg tttgatcatt tcggttaggc ttacaaaaag cacactctta
     4201 ggttctcctt ttgtcttata cccctcattt atacctttgg caatagcaac tgataaaagt
     4261 gtttttccaa tccctgtacc tcctgtgata agcgtatttc ccctcatgcc atcaagatat
     4321 ttttgtacct gaccttttgc aaattctaaa aatcgctttt cttctgatgt tacagcatta
     4381 aaatcatcaa aagttttagt tttaaactca tctgctacat agctcttatt gctcatcaac
     4441 acattataag tttgcagata tagtttagca ttcaaattat cagcaatcgc atcttcttca
     4501 tcttgctttt tctgttcttc ttggcattgt tcacaatagg gtgggataca gcgaacttct
     4561 tttattacct ctccgttctc attccacccc actactacat gtctttctcc tttgatttgt
     4621 gttagctgta tttcatgctt aggacacaat tcgtctagtt taaatgtctc aatatttcct
     4681 aaactagatt gtaatgattt cattttctga cctcctaaaa tggtttttct tgtgttggta
     4741 tccaatcttc atagctggta ggctctagtt gattggtttg ctgtttttta gcctcacgcg
     4801 ctgccctgct atttctaaca agttccaccg tcaataaatt gtcctgtttc caacggttaa
     4861 ggattgcctt gatgtatgca aagtttgctt taccctgact gacagcctct tttaacgcct
     4921 catggataag ctctgggcta aaatcttcta gcatatactg caattcttga atctgtaacg
     4981 gtgacaatgc tttacctgtc tcagcttcaa aagatttata gagatttaca aaatcttgat
     5041 tgatggtaga gggagtgggt gattgttctt tatctacttc tatctctaat tctttctcta
     5101 tctctgttgg acatgagttg gaaaatgtca aagatggttg gacttcttcc aattttcctt
     5161 tttttcgttg ttcacgttta taactcgccc agtttgtttc actcataacc atagcttttg
     5221 cctgtggtag ttctgcgttt ttatcttcgt caatctgtat taaaccgcat tttgtaaagt
     5281 atgccatggt catatctata tcatcttctg atacatctaa ttttagggct aactcttcct
     5341 tgagattgtt aaagtagccc tcatagtata aaatacagtc actttccaag ctctctaaca
     5401 tgagcctaat ataaataact gtcatagtgt acccaccagg taccgtcttt agtctcttga
     5461 taaaaatatt atcaaaaaat ttcttatcaa tttttagcca aaaatagact tttgtttttg
     5521 ccatcgtcct ctcccttgct catttataat tctctacctt gattagtctt aatactcgct
     5581 tgtcattcat tgttagactc attcaattct tccccatacg tctacccctg caagctggat
     5641 atatcgccca taatcagggt ttaaatcctc gctaggtgtt tctatcgtct gttggttttc
     5701 tcgctccagt tgggcgcttt ttttgcggtc tcggtggttt aaataaagca gtaagccaat
     5761 caaaatcacg gtaacaaaaa ccgcctgtgt attgcttata tctagttcat tcatgttatg
     5821 ccctcgcttt gtaattcttg atgtatgcca cttgttcagc tcgcttcata ttcaacaagt
     5881 cgtctatttc cacactggtt acttttttat ttacaaaatc agaaatcagt tgaaaaatgt
     5941 ttggactttg tagctggatt tcagccattg cctcatcaaa ttctgcttgt gtcatgttgt
     6001 ctaaatctag tgtcattgca ttgcctcctc aaacttctct ataagacaac ttttatttgc
     6061 tttctgagtt ccatttttag agttaaaaag aatatatttt aaggttacag tagcctctaa
     6121 atactccttt tcagcatgct ctatatacgc ctgttgctct gcttcgttct caaaaaagtg
     6181 cttagcttag cgtttaaaga atgctttgac taggtttagt ttgaattgcc gtactgcttc
     6241 ggtattcttt agataagtga tcagcaaagt agcctgttgc tcgttcagaa tataggattt
     6301 tttaggttgt cctctagtgt ctaatttatg gattttaaat ccaagtattc ccaactcttc
     6361 aaagtcaacc ttattttctc ttattaagcg tgtgatagtg tggtgttgta cgtcagcaca
     6421 ttcagcgatg atctcgcttg tggtatacgg ctctttcttg ccgtccatgt agactagttc
     6481 cattatggtt ctacctcctg tataaattta gctagcttac tttttaattg tctcctctag
     6541 ccctttttag cctctacaac ggttttggct aacgtgttag aggcttttat aacggcctgt
     6601 atagctgtct ctatttcctc cgtggaatag tagctttgtt ttctaatatc atttaagact
     6661 tgtttaaccc atttcttgaa ataaataaaa ttacatcttc tgtactcttg gcatctgctt
     6721 tatctgagac aaatagaatg tcaatgcctg gtagataaaa cccaccgtct atttgtttag
     6781 ttggtttgaa agtaactatt ttcatttcat aactcctatt ttattgctaa aaataaatac
     6841 acatctgaca gacgatagaa tactttctta gctccatcca tcggggtctg atatcgttta
     6901 agagcaagat cctcccagtt atcaagggtt gtagcactta tacctagcag atccattaat
     6961 tctttacgag aaattaaatc taacttacta gatcgttgtt tttctagctc aactaaagtt
     7021 tcaagagtct gtttaagaag ctgtaaaccc tgtaactgta tttctttaga cagaatttcc
     7081 atttatatcc tccattttcc tttttataaa ttaagttgtc tttttcctct aattttgata
     7141 aaataagaag agattattta gcaaaggggg ttgtcccttt gctaaatacc taacaaaacc
     7201 acgcgccttg cctttgcttg agttttgtta tttttcctta gccgtgtacg ttggtttggt
     7261 cgcctgtaca tggcttttta cttgcgttaa atttattcta ctagccaagt catcacgctc
     7321 tcatagatac gcttagaggc atcatagttt ccattctcaa cttttgttag tgtttgagat
     7381 ttaataccca actgctccga tactgctttt ttggttagct gtaatcttgc acgcttgata
     7441 cgtacttttt cagcaagtga tagtgtaatc aacattggtt tcacctccct tttttctcca
     7501 tttttggcat tttgtgttat aatctcttta gaaaggatgt ataagatgaa tagaattaag
     7561 caattacgaa aagaaaataa tcttactcaa agagaacttg ctaatgagac taaaatccct
     7621 tatagaacca tacaacgttg ggagaatggg gaaactgata taaaatccga tgctgctcag
     7681 gtacttgctg actattttgg agtatcaatt cctcacttac taggttatag cgatttgata
     7741 gcagatacag atagtgatat taaagcaatg gcatactcac atctactaac ttttgtagat
     7801 gaaaaacaaa tcaaagaatt tgaaaaagag ttcattcgtg caaacgataa tagtgatact
     7861 tttggtgatt taggaagtgg tgaaaaggcg ttagaaaaat actatcaagc attatgctat
     7921 ttagttcctc cttttaggga tatattggct aggtatagct ttttgtcact agatgaaaaa
     7981 aaatcagtct ataatattat tgttggttta agtaacaact tatcaaaaga aaataaataa
     8041 ctttaaacat catgtataaa tacctaacaa aaccacgcgc cttgcctgct gatggaaaga
     8101 aaggtacaaa tacatgaata tcatagagaa aattaaaaag aatggccaaa gagtttatta
     8161 tgctagtgtt tatctaggcg ttgaccaact aacgggcaaa aaagcccgta caactgttac
     8221 agcaaccact aaaaagggcg ttaaagtaaa agcgcgtgat gcgatcaata cttttgctgc
     8281 taatggctat acagttaaag ataagccgac aattacaaca tacaatgagc ttgtaaaagt
     8341 ttggtgggat agttacaaga atacagttaa gccaaatact cgccaatcca tggatggatt
     8401 ggttagagtg catttattgc ctgtatttgg cgattacaag ctatctaaac ttactacgcc
     8461 tattcttcaa cagcaagtaa acaaatgggc tgacaaggca aataaaggcg aaaaaggggc
     8521 atttgctaac tactccttgc tccataacat gaataagcgt attttgaaat atggcgtagc
     8581 tatccaggta atacaataca acccagctaa tgatgtcatc gttccacgca aacagcagaa
     8641 agaaaaggct gctgtcaaat acttagacaa caaagaatta aaacagtttc ttgattattt
     8701 agacactctg aatcaatcaa attatgagaa cttatttgat gttgtcctgt ataagacttt
     8761 attggccact ggttgccgta ttagtgaggc tctagctctt gaatggtctg atattgacct
     8821 agaaagcggt gttatcagca tcaataagac actaaaccgc tatcaggaaa taaattcacc
     8881 taaatcaagc gctggttatc gtgatatacc aatagacaaa gccacattac ttttactgaa
     8941 acaatacaaa aaccgtcaac aaattcagtc ttggaaatta ggccgatctg aaacagttgt
     9001 attctctgta tttacggaga aatatgctta tgcttgtaac ttacgcaaac gcctaaataa
     9061 gcattttgat gctgctggag taactaacgt atcatttcat ggtttccgcc atacacatac
     9121 tactatgatg ctctatgctc aggctagccc gaaagatgtt cagtatagat taggccactc
     9181 taatttaatg atcactgaaa atacttactg gcatactaac caagagaatg caaaaaaagc
     9241 cgtctcaaat tatgaaacag ctatcagcaa tttataaaaa ataagggtga cccatttccg
     9301 ggctaccctc ttactatacc aaaaattagt aggggtagta aaaagggtat taaattataa
     9361 aaagcactaa gggaaagcgc cccaaagtgc ttatttcaaa ggctttatag cctataatca
     9421 cataaggaga ttatttttta aggttgtaga atgatttcaa tccacgatat tcagctactt
     9481 caccaagttg gtcttcgata cgaagcaatt ggttgtattt agcgatgcgg tctgtacgtg
     9541 aaagtgaacc agtcttgatt tgtcctgcgt tagttgcaac tgcaatatca gcgattgttg
     9601 aatcttcagt ttcacctgaa cggtgtgata caacagcagt gtaaccagct tctttagcca
     9661 tttcgatagc ttcaaaagtt tcagtaagag taccgatttg gttaactttg ataaggattg
     9721 agttagcagc accttcttgg ataccacgtg caaggtagtc agtgtttgtt acgaagaagt
     9781 cgtcaccaac aagttgtact ttcttaccaa gacgttcagt aagagctttc caaccatccc
     9841 agtcgttttc atccatacca tcttcaatag tgatgattgg gtatttgtta accaattctt
     9901 caaggtagtc gatttgttct gcagatgtac gaacagcagc accttcacct tcaaatttag
     9961 tgtagtcgta aactttacgt tctttatcgt agaattctga tgaagcacag tcaaatccga
    10021 taaatacgtc tttacctggt acatatccag cagcttcaat cgcagcaagg atagtttcaa
    10081 caccatcttc agttccttcg aaacgaggag cgaatccacc ttcgtcacct acggcagttt
    10141 ccaaaccacg tgatttaagg attttcttaa gagcgtggaa gatttcagca ccgtaacgaa
    10201 gggcttcttt aaatgttggc gcaccaactg gcaagatcat gaactcttgg aaagcgattg
    10261 gagcgtcaga gtgagaacca ccgttgatga tgttcatcat tggagttgga agaactttag
    10321 tgttgaatcc accaaggtag ctgtaaagtg ggatttcaag gtagtcagca gcagcacgag
    10381 ctacagcgat agacacaccg aggattgcat tcgcacccaa tttacctttg ttaggagtac
    10441 cgtcaagtgc gatcatagca cggtcaatag cttgttgatc acgtacatcg tagccaatga
    10501 tagcttcagc aatgatgttg tttacgttgt caacagcttt ttgtgtacca agaccaccgt
    10561 aacgagattt gtcaccgtcg cgaagttcaa ctgcttcgtg ttcaccagta gaagctcctg
    10621 atggaaccat accacgtccg aaagcacctg attcagtgta aacttctact tcaagtgttg
    10681 ggttaccgcg tgagtctagg acttcgcgag cgtaaacatc agtaataatt gacatttttt
    10741 actctcctta tgagttaaat tttttacacc tctataatac cttaaaaccc ctcctttttc
    10801 aagaaaaaac gttatctttg tgcaactttt ccttaacttt ataaagtaat cgctttcttt
    10861 tgtctgtttt attctaactt ttatgatata ctgttttcat gacagattta tcaaaacaat
    10921 tacttgaaaa agctcatggt gggttaaaaa taaatccgga tgagcaaaga cgctatcttg
    10981 gtacttttga ggaaagagtt cttggatatg tagatattga cacagcaaat agccctcagt
    11041 tagaaaaagg ctttttattt attttagaaa accttcagga aaaagcagag ccactatttg
    11101 tgaagatttc accaactatc gaatttgata agcaagtttt ctacttaaaa gaagcaaaag
    11161 aaactgatag tcaagccacc atagtatctg aagagcatat tacttctcct tttggcctgg
    11221 ttattcatag caatgcacca gttcaagtag aagaaaaaga ccttcgactt gcttttccaa
    11281 aactttggga agttaaaaag gaagaaccag ccaaaacatc cttatggaag aaatggttta
    11341 gctaaatctt gcacatattt aataagtgcc caatattggc agccgtgcgc tccagataga
    11401 gactggcatt tttcaaacta tcttctaaag gttcactttt ctccaaaata gaaaagacag
    11461 cttggatatt ttcaaatggt aggggaggta aatcttcagc aagactaccg caaatagcaa
    11521 taacaggaac tccaacaggg gttctttttg caacacctat aggcgctttc ccagcaaagc
    11581 tttgactatc aagtcttcct tctccaacaa caaccaagtc agcatctgaa actttcttat
    11641 caaagttgat taagtccaag caggtatcaa ttccagacac gatacttgcc tgagcaaaag
    11701 cacacaaacc accagcaagg cctccacctg ctcctgctcc tttaatttct aatgttgcag
    11761 gtgagaattt ttcataaaaa tcttggatcg cctgatctac gactgcaaac atagtcggat
    11821 gtcgaccttt ttgattgcca aaagtataag tcgcaccttg atgaccacat aagggactta
    11881 cgacatctgc taaaatatga atttgaacac cttcaggaat tttatagcaa ttttctgttg
    11941 aaacagaagc taagtttaat aaggattgac cggaagcagg caagacattt ccatccctat
    12001 cataaaattg ataacctaaa ccagcagcaa tccccagtcc tccatcatta ctggccgtgc
    12061 caccaacatc gatataaata tctttaatcc ctttagaaat gagatggaga atcaactctc
    12121 caataccaca agtttggatt tgaagtggat ttcgtttctc tagcggaatt tttccaagac
    12181 caaccaagtc agctacttca aatagtgcca gttccccttt ttgaaaatag cgcatggctt
    12241 ctttttgtcc aaaagggtct gtcacttgga tccatttttc ttttaggtca agagaatgtc
    12301 ggatagcatc tacagtacct tctcccccat caccaacagg gcagaggaga cattctacat
    12361 ctgctatcga ttgttggaag cctcttttta ttgcttcagc tacctgttga gctgtcaagc
    12421 tttccttaaa cgaatccggt gcaattacaa tcttcatatt ttccctcatt ctaaacagtc
    12481 aatcaaagga agaacttcta aaaaatccct cttgtcaaca tgatgtggta tttctttttt
    12541 gagcatttct ttggaacaaa aggcgattcc taactccgcc gacttcaaca ttaatagatt
    12601 attgccccca tcaccgattg ccaccgttct ttctttagaa agttttagtt tctttctcca
    12661 tttttccaga gtttcttttt tgacctgggg acttataatt tgtccaacta attttcctgt
    12721 taaaagacct tctttgactt caagctggtt agcagtgaaa taggcaatac caagggattt
    12781 tgctaatctc tccaactatt ggtgtaaatc caccagacac cagaccaact aggataccat
    12841 tcttttggag aatagagatg aactctggga catttagcga tagatgaatt gagttgaaga
    12901 cgttatcaaa gaccaaaata ggaagacctt ccaacaagga cactcttttt cttaaactgc
    12961 tttcaaagac caactctcct cgcattgctc gacttgtaat ctgcgaaatt tctgcctcat
    13021 gacctgcctc tctccctaaa agatcaatca cttcttctag gattaaggtt ccatctacat
    13081 ccaaaacaca caagcctttt acttgagaca tcagttctcc tctctaaaca gcctaaaaat
    13141 cgtatgaagt catcatacga ttttatctat taattaacta aactatggta caagtcaagg
    13201 tatgacttgc aggctgtatc ccatgagaag tcactctcca tagcttgttt ttgtaggttt
    13261 ctccaaatgt ctggatggtt tctatacaag tccaatgctg tttggaaagt ccaatttaac
    13321 caataaggag atagattgtc aaagctaaag ccagtaccgc ttccttcgat tggattgaaa
    13381 gcgcgaactg tatctcgcaa gcctccaact tcatggacca atggcaaggt tccataacgc
    13441 atagccatca tttgagacaa gccacacggt tcaaaacgac ttggcatgag gaagaggtca
    13501 caagcagcgt agatttcctg agcaagtttg acatcaaaag tgatatttgt tgatagcttg
    13561 tctgggtaaa tctgagcaaa ccatgagaaa gctccttcaa aggctggatc gccagttccc
    13621 aaaagaacaa tctgaacatc ttcttgcaag atatggtgaa gactttcgac caccacatca
    13681 aaaccttttt gacgtgtcaa acgagaaaca attcccacca gtggaacgtc tgctctaaca
    13741 ggcaagccaa ctctttcttg caattttgcc ttatttttgg ctttcccaga caaatcttcc
    13801 tgattgaaat gatagtctaa aagagcatcc gtctgaggat tataaagatc agcatcaatc
    13861 ccattcacga taccagatac tttaccagac tccattttaa gaatctgatc caaattacat
    13921 ccaaactgac tagtcataat ttcatgagca tagctaggtg aaacggttga aacacggttc
    13981 gcatagagaa tacctgcctt catccagttc agacagttgt tccatcgaag ggtgccatca
    14041 gcgtaacgtt caaagccaac tccaaacaaa tcacccaaca ttccttctga aaattgtcct
    14101 tggaattcta aattatgaat ggttaaaact gtttcaatgt cctcataggc ttgaatccaa
    14161 cggtattttt ccttcaacaa gaaaggaatc atagctgtat ggtagtcatg aacatggaga
    14221 agatcaggaa taaagtcaat cctttccata gcctcaatgg cagccagttg gaaaaaggca
    14281 aagcgttctc cgtcatcaaa atcaccgtaa acatgaccac ggaagaaata atattgattg
    14341 tcaataaagt agaaggttac accatttaat actgttttct taattccaca atactgtctg
    14401 cgccaaccaa cgctcacctc aaaatgaagc acatcttcaa tctgatttcc aaatttagcc
    14461 tctaccatat catagtaggg taaaatcact gcaacttcgt gcccagcttt taccagtgat
    14521 tttggaagag cgccaatgac gtctcccaaa ccacctgttt ttgaaaaggg tgcaccctct
    14581 gctgctacaa ataaaatttt catgaatgaa tatcctctgt tactttagca cctttcttaa
    14641 ccacaactgg atgttctgca gttcctcgaa tcacaacacc aggctcaact tcaacccctt
    14701 tgtccaagat agcatattcg acctgagccc cttctccaat aacaacacga gggaagagca
    14761 ggctatcttt aaccaagcta tccttatgga catggatatt acgtgataga acagaattag
    14821 ctacttgacc ttcaataata ctaccagagg caaactgaga agttcttacc ttagatgtat
    14881 tagcatagta agttggctct tcgtttttga cctttgtata aatcttttgg tttggtgaga
    14941 aaagagaata gaatttttgt gattcaagca tatcgatatt cgcttgataa taagatttaa
    15001 cagagtgaat attggctaga tagcccgtgt actcgtaggc gaaagctccc tcttttacag
    15061 ccaaatcccg taaaacatag cgcaatttct ctggatgttc ttttttagct tcttcttcca
    15121 agtgttcaat caaccaaggt gtatcaacga caaagatatc tgtagacata ttgaacgttt
    15181 cagctgttga cttgctatca aagagtttat gagaaagaac atggtctgtt tcatctacat
    15241 ccaagattgc atttacttct gaaatatctt tcttagctag ttttttataa actacagtga
    15301 taggctcttt tgttgtacta tgtaggtgga aaacttggtt caaatcaatg ttaataagaa
    15361 catcgcagtt gagggcaacc gtttggtttg agccagaacg tttcaaataa gtaagaagct
    15421 gttggtagta ttcttttcca actgtactac tttctacacg ggtattgtaa attcctagat
    15481 agtaatggct aagaaaggtt gataagcccc actcgcgtcc tgaacgaata tggtcaaata
    15541 ctgagctgat attatcctgc tggaaaatac caaagacact acgaacacct gcattagcaa
    15601 ggcttgaaag tgggaagtca atcaaacgat atttcccacc aaatggcaaa cttgctactg
    15661 gacggtggtc cgtcaatgtc gacatattgt gaaaaccaac tgtatttcct aaaatggcag
    15721 aatatttatc aatcttcatc tgttgctacc cccactactt cattatatcc tacaacttgt
    15781 acttcatctg ttccatcaat ttcgacaccg tcagaaataa tcgcaccttc accaataatg
    15841 gcacgtttaa tcttagctcc ttgaccaatg atagctccac tcatgataac tgaatcaagg
    15901 acttccgctc cttcgcgaac ttgcgcgcct gttgaaagga tagaatgttt aacagttcca
    15961 tcaacgaaac atccgtctac aactaatgag tcttccacat gagcatttgc cccgaggaag
    16021 tttggtggtg aaatcaagtt tcttgagtaa atcttccatt gacggttacg actatccaag
    16081 gcattttctg gagaaatata ctccatgttc gcttcccaaa gtgactcaat agtaccaaca
    16141 tctttccaat aaccactaaa ttcgtaagca taaacacttt cacctgactc aaggtaattt
    16201 ggaatgacat ttttaccaaa gtctgacatg ccaaccttgc tcttttcagc agcgactaac
    16261 atattacgaa ggcgttgcca atcaaaaatg tagattccca tagaagcttt tgtagattta
    16321 ggttgagctg gtttttcttc aaattcaaca atacgattgt tagcatctgt gttcatgata
    16381 ccaaaacggc ttgcttcttt aagagggacg tctaaaactg ctactgtcaa gctggcatta
    16441 ttatccttat gagactggag catatcatca tagtccattt tgtagatgtg atccccagac
    16501 aaaatcaaga catactcagg attgacactg tcgatatagt cgatattttg gtaaatagcg
    16561 tgactagtcc cctcaaacca acgatttcct tcacttgcag aataaggttg aagaatagag
    16621 acacctgaat taataccgtc tagtccccag cttgaaccat tcccaatatg gttgttgaga
    16681 gcaagtggtt gatactgtgt aacgacccca acattatgaa tccctgagtt ggcacagttt
    16741 gatagggcaa agtcaatgat acggtagcgc ccaccaaatt gcacagctgg ttttgcgatg
    16801 ctttgagtga gtttaccgag acgagttcct tgcccaccag caagaatcaa agctaacatt
    16861 tcatttttca ttttctactc ctttttggtt tttatttgtg acggttttag tagatttcaa
    16921 gcgacgtttg attttccata cacttgctcc catagccggt agggtaaagg ttaaggtctg
    16981 ctcataatct ttccatagtc cttcttgcgt ttgaacagtt tgattatgtt ctttccaaac
    17041 gcctccccac tcttccaact cagtattcca tacttcttcg taaattcctg caacgggtag
    17101 tccgattgta aaatctttcc gctcaacagg taccatgtta aagatacaga ctaacatttc
    17161 tcccttttta cccttacgaa taaaggaaag aacactctgg tctcgattat ccgcatcaat
    17221 gacttcaata ccatcatagc tggtatcgat ttcccacaga cagcgatgat ctttgtaaaa
    17281 ctggtttagc tgagaagtga aatacttcat cttagcattc attgggtctt ctaggttaga
    17341 ccattccaac tgttcttcag atttccattc taggaattga ccgtattcgc tacccatgaa
    17401 gagcaatttc ttaccagggt gacaaatttg gtacgtatag agattgcgca agcctgcgaa
    17461 ttgattgtaa cgatctcccc acatcttatg catcatactc ttcttgccat gaaccacttc
    17521 atcgtgcgag aatggcaaga gataattctc cttgaaaaca tacataaagc tgaaagtcac
    17581 caggttaaag tcatatttac gataaatcgg atcttcttcg tagaaacgga ggatatcatt
    17641 catccagccc atgttccatt tgtagtcaaa tcctagacca ccaatctctt tcattcccgt
    17701 aatcttggtt gcagacgaac tttcttctgc aatcatcatc acatctggat attctaactt
    17761 aataacttca ttcaagcgtt gaaggaaata ataaccttca tagttgagat ttccgccatc
    17821 tttattaggt gtccatggag catcatcata gtccaaatag agcatgttgc taacagcatc
    17881 cacacgaata ccatccaaat gatagatatc aatccaatgc ttaatgcaag aaattaagaa
    17941 ggactggact tcattttttc caaggtcaaa attaagggca ccccaaccat ggttatgagc
    18001 cttattatgg tcttggtatt caaaagtcgg tgtcccatca taataggcta aggcatcatc
    18061 attgatggta aagtgacctg gtacccagtc cacaataacc ccaatattat gggtatgaca
    18121 ctcctcgaca aaatcttgaa actcctctgg tctaccatag gcatgctcta aagcgaagta
    18181 acccataagc tggtaccccc aactcaaacc tagtgggtgg gacatcaagg gcataaactc
    18241 aatatgagta tagttcatct caactaggta aggaatgagt tcatctttca attgggcaaa
    18301 actataagga ctgccatcag gatttctctt ccaagagcca gcatgaacct cgtaaatatt
    18361 gacaggacgt tcagcaaagc cccaacgttt tcttcgtgcc agccaaagtc catccctcca
    18421 tttcttatca ggaagctctg ttacgattgc ccctgttcct ggacgagcct catacctgac
    18481 agcaaaaggg tcaatcttca tcagttgatg accattttga cgtgtgacat gatatttgta
    18541 aatatgccct tcttgagcca tattggtaaa gacttcccag accccaaagt catttcttac
    18601 cattggaatc tgattttcaa tccaattggt aaaatcacca accaagtgaa cagcctgagc
    18661 attaggtgcc caaacacgga aggtatagcc atactctcca tttagttctt ccctatgtgc
    18721 tcctagataa tgttggagat aaaaattttc acccgtcata aaggttttta atgcttctct
    18781 attatccata tactcccttt ctcctgtaag cgttttctat gtttttatta tactaccttt
    18841 ttagagaaga ttcaagtaaa ttactatact tctttaatta ttttgaaaat ctacaacaag
    18901 ttcacttact cgttcaattg taaatcaata ttttttcaaa aaattgcgaa aacacctttc
    18961 tttttctact atagtgaaat gaaataaaac atgcgcaaat cgattaagga atttaatcta
    19021 atttctaaca atgtcttaga aatcaaagtg tactatttta acttcaatgt actatatata
    19081 gtaaaatgaa ataataacag gacaaatcga tcaggacagt caaatcgatt tctaacaatg
    19141 ttttagaagt aaatctgtac tattctagtt tcaatatact ataataccaa aaagttcgta
    19201 ttttttctat aattattatt attttatagc aaaaaataaa accaggaaaa caatttcctg
    19261 attttacacg ttatttcaca tcaaaaacaa tggatttgac atttgtcatc gcttcaatgc
    19321 tatatttaat tccttgcact ccagctccag aacctttgac accaaggaat gggaaattat
    19381 ctggaccacg ctgggtttta ttattaatgt ggactgtacc tacttcaagt ttttcagcaa
    19441 tttcaaaggc ttttttgaaa tcatttgtaa agactgatga ttgaaggccg aattcagatt
    19501 cgttggcaaa ggcaatagct tcctctacac tagccacacg aatgattggt aaaacaggac
    19561 caaatggctc ttcccatgcc actttcatat cttttgtaac ttggtcaaaa agcactggcc
    19621 agaggagatt gccctcacgt ttgattggtg taagagcctg agcctctttt tcttgtgcat
    19681 cctcaatcaa gccccaaatg aagtcggctg aagcattgtc aataacaggt gtaatatcag
    19741 cattgtcaaa tggatcacca actgttaatt tagaaacttc ttcctgaagc aaagtagcta
    19801 atttatctgc tacactttcg agaacaatga cacgtttaat ggccgtgcaa cgttgtcctg
    19861 agtagctaaa ggctcccgca acaatttgct tggcagcatg ttccaaatct gcatcttcta
    19921 gtacaagagc tgcatctttc ccaccaagtt ccaacatgat aggacgcata ccagctaaac
    19981 gaccaatacg ttctccaata ggagttgaac ctgtaaagtt gatgaagttg acttctttgt
    20041 gctcaatgat ataatcccca atttctgaac cacgacctgt aatggtgttg aaaacacctg
    20101 ccggaatccc tgcttcttca aatgctttag ccaacaagag tccagaaatg gaaccttgtg
    20161 ttggtggctt caacatgacc acattccctg caatcaaggc aggtgcaatt ttagaagcag
    20221 ataaattaac tggataatta aagggagcaa tcgctagcac gataccaact ggttcacgac
    20281 ggacaacagc cagtttgttt ttacttgctg cctcaaaacc accaccttcc attgcttgtc
    20341 cagtgatacg gagaccttcc tcagcagcat aacgaatcaa gtctgctgta cgcactactt
    20401 ctccaattgc tgctttaatc ccttttgcta cttctttggc aaggatagta ccaatttttt
    20461 ccttatcgcg ttctaaaata gctgctgttt tatgcaaata agccgcacgt tcaattgctg
    20521 ataaagctcg ccatgctggc agggctgcac gcgcagcttg catagcctca tcagcttcag
    20581 tctgagtcat ggctggaact gtacccaatt cttcttgatt gattggtgaa taaatcgtaa
    20641 tttcttgttc agatgatttc cattttccat ttactaaatt ctgatatctt gtcaaattct
    20701 tgtcctcctg aaaatgatta agatatattt taccaaattt tcagaaaata acaacccttt
    20761 ttgcaaaatt tttgagatta ttttcacaag cttgattttt caaagtatac tcaataaaaa
    20821 taaaaaaatc cactacgtca aggcgaggct aatgtggttt gaagaaattt tcgaagagcg
    20881 tgaatgagta tcatctatag taaaataaaa aaactgaaca atttggttgg ggacagccaa
    20941 accaatttct cacaatgttt cagaaacaag ggtgtgctat tccaatttca gcctactata
    21001 actgtcatag attgctgaaa caaagtctag gtaaaagtct tcataataaa aagacctcct
    21061 atcaaatgtt caaaaacttt gataggaggt cttgtttcgt gaaaatattt atcaaatttt
    21121 ctatacaagt gagctgttag ccaggttctt tctattcttt caatttcaat gaatggattt
    21181 tttaccaata ctcataactg ggaatttttc tgtctaaaaa tagcgagata gatggtattt
    21241 ataaaacact caagacagct agactaatat catttaaaac attatcttct tttgagcgac
    21301 tgttggttac caacatagct aaatttcctg cattttcaaa ttgatagggt tctgatttag
    21361 cattcacaac taccaagagg tgttctttgc cgtgaacttc atagataagg cagccgctat
    21421 gttcaatcgc agaatgcaca aagacatgat ggtaaatttc atcatagcta gagtaagaaa
    21481 aggcaccagt ttttgtcttc aatcggatga cttgacggat aaactcaata ctgtcttgac
    21541 gctcattaat caagttccag ttcacttggt tcacactgtc aggagcatta tagctattca
    21601 tcgcacgctc tctatcatca tgggtcaact caccattttc accagtcgca accagtttgg
    21661 tacgaccaaa ttcttgaccg atttccataa aggccatccc ctgcatgagc agattcatgg
    21721 ctgtggcagt ttcgaccttg cgcatgattt gctctgaact ttggtctgga tgaagggttg
    21781 ccaataaatc gtgaagattg taattgtcat gggcttctac atagttaagc acctgatttg
    21841 gatgtgtata gcttcctaat tcacgacttc ctaggattgc tttagctaga attggctctg
    21901 tcgcagcacc actgacaaaa cctgacttga tagcaccata aacttctccc cctttgacag
    21961 catcgcgctg attgtcatta aagaaaccaa tatttggcat ctggtaggca ttgtccttct
    22021 tggccttatc ataaggggca agacctgttc ccatatccca tccttctcca tagaggataa
    22081 tgttggagtc aatttcatcc aagctttgac gaatcatctg catggtcttg acatcatgaa
    22141 tccccatcaa gtcaaaacgg aagccgtcaa tattatattc ctgcacccag tatagaagag
    22201 aatcaatcat atacttgcga aacatttcgt gttcactggc tgtttcattt ccaacacccg
    22261 ttccattctg gaaggtacca tctggattca tacgataata gtaatcaggg actgttgttt
    22321 ggaatggtgc atcaacaact gagaaggtat ggttatagac tacatccata atgactccaa
    22381 tacccgcatc gtgataagct tgaaccatca ccttcaaatc acgaatgacc tgagctggat
    22441 catctggatt agttgaaaaa ctagtttctg gcgcgttata gttttgtgga tcataacccc
    22501 agttgtaggt tacatttcca tcctcatcgt attctttatg acggtctgca attggttgca
    22561 attgaacata attgtagccc agcttcttga tgtaatcaaa agcagttgac tggccgtatt
    22621 ggttaactgt tccagcctga gcagcaccca agaaagttcc tcgaagatgt tcatctacac
    22681 ccgatgtagg tgatttagtc aaatcacgaa tatgcatttc acagataact gccttacatg
    22741 gattttccaa gcgccaagta gcctccgaac cgtgcttaac ctcgaagttt tcaacttgct
    22801 tttctacatg gctcagaata gctgaacgtt tgccatcagg gctggtcgcg attgtataag
    22861 gatcacgtgt cagtgtttgg tgatgaggga attggacttg atactgataa gtcttaccta
    22921 ccaaatcttc ttcaacatcc aaactccaga caccgattgt attgtcctta tgattataag
    22981 agtagctatt gcctcttttc atctcaaaag tcttccaaac gggtgcatca ttagcagctg
    23041 attcataaac gacaacttgc acttctgtcg ctgtaggtga ccagagggaa aaatgagcct
    23101 gattgtcctc tacacggcaa cccaattctc cttggtaacc ccaatgatga tcaaaactag
    23161 cactgttaat ggccttatca aaggcaaaag gattttgatt tttatagaaa ggactggcaa
    23221 tagcaggatt ttcagagtaa taaatcctat catcgccttc caaaatccag acctctgtta
    23281 ataggggata gtgattaaaa cggatagaat attctttact agtttgacct gtatgaacca
    23341 caaaattcaa gctttctata acatgtgaac ttgggtgttc aaagctaaat aaagctccaa
    23401 aataatcttc tttgtaggtt agcaaatcaa ttcgttgatc ctgacttttt acaaaggagc
    23461 aagtgtcata ttctccattc ttacgatggt aatgaatgcg catagggtag ttatacattt
    23521 tttatttttc ctttttactt tgtttctatt tcactaataa atttttgtca atctcgtctc
    23581 aattaacaga catagtcata ttctctaaac tctgttttta aacgatccat tacaaacttt
    23641 ctagccatgc ctcatctctg acctggatac caagttcttg tgctttttgc agtttacttc
    23701 cagcgtctgc acctaccacg acgaggtcgg tctttttaga aacactacct gtcactttgg
    23761 cacccagact ttcgagttta cttttagctt ctgagcgctt gagtcgttcc aattttcctg
    23821 tcaataccac ggtcaaacct gacaaggccg catccgctac taccgtctgt cctttatagt
    23881 ccagattgac cccagtttct ttcaattctc tgagcagaat ttcagagcct tctgtcgcaa
    23941 aataagtctg aagacttttg gcaatcacgc cacctagact ttcaatacta gccacttcct
    24001 ctgaatctgc ctgagacaga ttttcaattg aatggaaata ttgaagtaaa agctgactag
    24061 ccttgcttcc gacatgacga attcccaaac caaataagag cttctcggca gaattttcct
    24121 ttgatgcttg gatagcctga tacagtttag cagcggactt ttccttaacc ccctctaaaa
    24181 ggaggaaatc ctcttcttgc aaacgataaa tatccgccac atccttgact aaattagcag
    24241 caaaaagctt ctcaacaata gatggaccaa ggcctgtaat attcatagca tcacgagaag
    24301 caaagtgaat caagccttcc atgatttgag cagggcaacg cggattgata caacgtaggg
    24361 ccacttcatc ttcaaagtgc aacaagtcag agttacaact tggacagttt gtagggatat
    24421 ctagtttttc ttcagaaacc cgtttggact ctaccacacg taaaacggca gggatgatgt
    24481 caccagcctt atatacaatg accgtatcgt cttttcggat atctttttca gcaatataat
    24541 ctacattgtg cagggtcgca cggctaacag tcgtaccggc aagttgtact ggtgttagat
    24601 tagcagttgg agttacaaca ccggtacggc caactgtcca gtcaactgat aagagttgag
    24661 cttctttttc ttcagcaggg aacttgtagg ctactgccca ctttggagcc ttaacggtaa
    24721 aaccaagttc ttcttgactt gctaggtcgt tgaccttgat taccactcca tcaatatcgt
    24781 aaggcagatt ttcccgttcc tgtcctactt cttggataaa attccagatt tcatctatgt
    24841 tttcagccaa gattcgctta ggattgacca caaaacctag ttgttctagg tacttcaaac
    24901 ccttttcttg gctatcacga gttgaagggc tggcttcttg atagagaaac gttgcaagat
    24961 tacgcttggc aactactgct gtatccaact gacgcagagt tcctgctgcc gcattacgag
    25021 gattagcaaa ttcaggctct ccattttctt ggcgcacttg gttaacttgg tcaaaggaag
    25081 cgcgtggcat gtaacattcc ccacgaactg tgatatctag ttcttctggc aaagtcaaag
    25141 ggatgtcctt aacacgcttg aggttttctg tgatattttc accaattgaa ccatctccac
    25201 gtgttacccc agcaaccaaa atcccctttt cataagtcag cgagatagat aagccatcga
    25261 ttttcagctc acaaatatag gtcggatgag ccacttcctt acgaacacgc gcatcaaaag
    25321 catctagctc ctcacgtgaa aaagcatcct gcaaactata aagaggatac tgatgactgt
    25381 atttttcaaa accatctaaa accttgccac caacacgatg agtcggactg tctgctagca
    25441 cttgctctgg ataagcagtt tctaactcga ccaactcacg gtaaaggcgg tcatactcac
    25501 tgtctgaaac cgagggatta tcgctggtat agtactcagt cgcatagcga ttgagcaaag
    25561 cgactaactc attcattctt ttattcataa gaccatttta ccataaaaca agccctcctc
    25621 acaaacgaga agggcggaaa aaacacttag tttgaaatta tttttgaaac tcaagcaacc
    25681 ttatatcaat ttttcaaaat gagttcgaac ataaataaac gatatacaag acaagatgat
    25741 aacaccactt ccaattatca ggaaagaaga gagatgtaca cttggcaaga ctgtcataaa
    25801 tccttttgca ataggcataa atagaatagc taaggtaaaa attgtactca gtactcttcc
    25861 aagaaattcg ctctcaacct tggtttgtac ttgagtaaaa aagt
//
LOCUS       DAVBIC010000031        24482 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.031, whole genome shotgun sequence.
ACCESSION   DAVBIC010000031 DAVBIC010000000
VERSION     DAVBIC010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24482)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24482)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24482
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.031"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            137..1312
                     /gene="mutY"
                     /locus_tag="VQ664_001262"
     CDS             137..1312
                     /gene="mutY"
                     /locus_tag="VQ664_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HET2789421.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATAPEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     LIEVDNFSQEEQFDLFHQVAEESVNFGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            1367..2071
                     /locus_tag="VQ664_001263"
     CDS             1367..2071
                     /locus_tag="VQ664_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2789422.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            2064..3413
                     /gene="vicK"
                     /locus_tag="VQ664_001264"
     CDS             2064..3413
                     /gene="vicK"
                     /locus_tag="VQ664_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HET2789423.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     HLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            3415..4224
                     /locus_tag="VQ664_001265"
     CDS             3415..4224
                     /locus_tag="VQ664_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HET2789424.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
     gene            4315..4557
                     /locus_tag="VQ664_001266"
     CDS             4315..4557
                     /locus_tag="VQ664_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HET2789425.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVADLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            4559..4813
                     /locus_tag="VQ664_001267"
     CDS             4559..4813
                     /locus_tag="VQ664_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HET2789426.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQTNVLEDPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHRRDIY"
     gene            4860..5633
                     /locus_tag="VQ664_001268"
     CDS             4860..5633
                     /locus_tag="VQ664_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ion transporter"
                     /protein_id="HET2789427.1"
                     /translation="MKKKWFFADYYDTTIILLALISVILVLLGFAEMIDLDNPPYSII
                     DLVIWGVFVIDYSWRFFTTKRKWRFILENIFDLLAILPLNAIFTVFRLGRIFRLAKLT
                     KLLKLTRLLRIIGLTGKLERKISRFLRTNGLIYILYVNIFIVLVGSSILSVVEEKSFS
                     DSLWWALVTVTTVGYGDIVPASIFGKWLAVLLMLVGIGTIGMLTSALTNFFVKDNPDE
                     QIKLDKLKDELSSQRILLEKQSKKIEELHKMIQDLIEKT"
     gene            complement(5893..6879)
                     /locus_tag="VQ664_001269"
     CDS             complement(5893..6879)
                     /locus_tag="VQ664_001269"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HET2789428.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGLYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            7073..9541
                     /gene="gyrA"
                     /locus_tag="VQ664_001270"
     CDS             7073..9541
                     /gene="gyrA"
                     /locus_tag="VQ664_001270"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003244540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HET2789429.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIALRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMIGQVLSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLAEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEE"
     gene            9541..10284
                     /gene="srtA"
                     /locus_tag="VQ664_001271"
     CDS             9541..10284
                     /gene="srtA"
                     /locus_tag="VQ664_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HET2789430.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSDEILTAFNQPYKQFY"
     gene            10528..11325
                     /locus_tag="VQ664_001272"
     CDS             10528..11325
                     /locus_tag="VQ664_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HET2789431.1"
                     /translation="MVSSEFISKIEFACNKKESLYSQSKFKYAIRSMFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISW
                     RKTAEILLYCTLFNLIGALIAGWGFAHSAAYANLTHDSFISGVVEMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGLLMGLPYAFLNKNEDTYVD"
     gene            11473..11595
                     /locus_tag="VQ664_001273"
     CDS             11473..11595
                     /locus_tag="VQ664_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent transferase"
                     /protein_id="HET2789432.1"
                     /translation="MTCDFKFETLQLHAGQVVAPATKSRAVPIYQTTSFIFDDT"
     gene            11617..12657
                     /locus_tag="VQ664_001274"
     CDS             11617..12657
                     /locus_tag="VQ664_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001231001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
                     /protein_id="HET2789433.1"
                     /translation="MRKPGNIYTRITNPTTAALEGGVEALATASGMTAVTYTILALAH
                     AGDHVVAASTIYGGTFNLLKEPLPRYGITTTFVDVDNLEEVEAAIKDNTKLVLIETLG
                     NSLINIPDLEKLAEIAHKHQIPLVSDNTFAIPYLINVFSHGVDIAIHSATKFIGGHGT
                     TIGGIIVDSGRFDWTASGKFPQFVDEGPSCHNLSYTCDVGAAAFIIAVRVQLLRDTGA
                     ALSPFNAFLLLQRLETSSLRVERHVQNAETIVDFLVNHPKVEKVNYPKLADSPYHALA
                     EKYLPKDVGSIFTFHVKGGEEEARKVIDNLEIFSDLANAADAKSLVVHPATTTHGQLS
                     EKDLEAAGVTPN"
     gene            12828..14102
                     /locus_tag="VQ664_001275"
     CDS             12828..14102
                     /locus_tag="VQ664_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HET2789434.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMKQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHEALLAKDKEV
                     QLLENQLATLRLEHENQLQKTLSDLEKERDQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKDFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            14112..14990
                     /gene="truB"
                     /locus_tag="VQ664_001276"
     CDS             14112..14990
                     /gene="truB"
                     /locus_tag="VQ664_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HET2789435.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMVEFMQDEGKIYEGEIILGYSTTTEDASGEVVAETPVLSPLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALTLEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            15258..15533
                     /locus_tag="VQ664_001277"
     CDS             15258..15533
                     /locus_tag="VQ664_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HET2789436.1"
                     /translation="MEQLLQQKEINENSELSHLFRLAIQNLDRNEKYQSVMANLSQGL
                     SLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            15641..16279
                     /gene="udk"
                     /locus_tag="VQ664_001278"
     CDS             15641..16279
                     /gene="udk"
                     /locus_tag="VQ664_001278"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HET2789437.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            16407..17747
                     /locus_tag="VQ664_001279"
     CDS             16407..17747
                     /locus_tag="VQ664_001279"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HET2789438.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLAHLQNQEK
                     RMATAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESVVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            17725..17937
                     /locus_tag="VQ664_001280"
     CDS             17725..17937
                     /locus_tag="VQ664_001280"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HET2789439.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            17934..18809
                     /locus_tag="VQ664_001281"
     CDS             17934..18809
                     /locus_tag="VQ664_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HET2789440.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLESLQVTIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDPYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQLPFE
                     TESIVSVVESLRING"
     gene            18802..19617
                     /locus_tag="VQ664_001282"
     CDS             18802..19617
                     /locus_tag="VQ664_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HET2789441.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHSVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKIHQNVLESVTAMAVEA
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            19610..20041
                     /locus_tag="VQ664_001283"
     CDS             19610..20041
                     /locus_tag="VQ664_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HET2789442.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIETFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            20048..21715
                     /gene="recN"
                     /locus_tag="VQ664_001284"
     CDS             20048..21715
                     /gene="recN"
                     /locus_tag="VQ664_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HET2789443.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRTIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLDLNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVRFSKGKFSREGNKMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQHGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            21717..22445
                     /locus_tag="VQ664_001285"
     CDS             21717..22445
                     /locus_tag="VQ664_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HET2789444.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQPQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYSRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEAADLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            22524..24347
                     /gene="lepA"
                     /locus_tag="VQ664_001286"
     CDS             22524..24347
                     /gene="lepA"
                     /locus_tag="VQ664_001286"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HET2789445.1"
                     /translation="MNLEELKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMELERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPERVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
BASE COUNT         7394 a         4339 c         5673 g         7076 t
ORIGIN      
        1 aacctgcggc tagcttccta gtttgctctt tgattttcat tgagtataag tagatagaaa
       61 agttatatac tatctattga aaatattata aatcagatac aaagacaggt gaaaccttct
      121 gtgttatact agagatatgt tagatttgaa agaatacggt atcgtcatgt ggccggagga
      181 gaaagtcatt tctttccgtg agaaacttct cgcttggtat gatgaaaaca aaagagattt
      241 gccttggagg agaagtaaaa atccttatca catctgggta tctgaaatca tgcttcagca
      301 gaccagggtg gatacagtta tcccttacta cgaaagattc ctggactggt ttccaactgt
      361 cgaaagtctg gcaactgcgc ctgaggagag tttactgaaa gcttgggagg gcttgggcta
      421 ttattctcga gttcgcaata tgcaggctgc agcccagcag attatgactg actttggtgg
      481 ccaatttcca aatacctatg aaggaatttc cagcttgaaa gggattggac cttacacagc
      541 aggagccatt tccagtattg cttttaactt gcctgagcca gctgtagatg gtaatgtcat
      601 gcgggtcttg gcgcgtctgt ttgaagtcaa ccacgatatt gggattccaa gtaatcgaaa
      661 aatttttcag gcaatgatgg agatcttgat taatccggat cgtccgggtg attttaatca
      721 agccttgatg gacttagggt ctgatattga gtctcctgta aatcccagac ctgaagaaag
      781 cccagtcaag gactttagtg cggcatatca gaatggaacc atggaccgtt atccaattaa
      841 atctcctaag aaaaagccgg ttcctattta tcttaaagca ttagttgtga aaaattctca
      901 aggacaattt ttacttgaaa aaaatgaaag cgaaaagctc ttggcaggtt tttggcattt
      961 cccccttata gaagttgata acttttcgca agaagagcag tttgacctct ttcatcaggt
     1021 tgcggaagaa agtgtgaact ttggccccag tccagaagag agtttccagc aggactatga
     1081 cctagatgtt gattggcttg atgtttgttt tgatacagtc cagcatgttt ttagtcatcg
     1141 aaaatggcat gtacagattg tagcaggtca ggtgagtgac ttccatgatt tttcagatag
     1201 ggaagttcgt tggctttcac cagaagaatt caagaattac ccacttgcca aaccccaaca
     1261 aaaaatctgg caggcttatg cacaagccaa cttagacagt agccaagact agctattgtg
     1321 tcttctgact attttttggt ataatagtag agaaaaaggt gaacatatga aaaaaatact
     1381 aattgtagat gatgagaaac caatctcgga tattatcaag tttaatatga ccaaggaagg
     1441 ttacgaagtt gtaactgctt ttaatggtcg tgaagcgcta gagcaatttg aagcagagca
     1501 accagatatt attattctgg atttgatgct tccagaaatt gatggtttag aagttgctaa
     1561 gaccattcgt aagacaagca gtgtgcccat tcttatgctt tcagccaaag atagtgaatt
     1621 tgataaggtt atcggtttgg aacttggggc agatgactat gtaacgaaac ccttctccaa
     1681 tcgtgagttg caggcgcgtg ttaaagctct tctgcgtcgt tctcaaccta tgccagtaga
     1741 tggtcaggaa gcagatagta aacctcaacc tatccaaatt ggggatttag aaattgttcc
     1801 agacgcctac gtggctaaaa aatatggcga agaactagac ttaacccatc gtgaatttga
     1861 gcttttgtat catttagcat cgcatacagg tcaagtcatc acgcgcgaac acttgcttga
     1921 gactgtctgg ggttatgact attttggtga tgtccgtaca gttgatgtga ctgtacgacg
     1981 tctgcgtgag aagattgaag atacgcccag ccgaccagag tatatcttga cgcgccgtgg
     2041 tgtagggtat tacatgagaa ataatgcttg atttactgaa acaaaccatt tttaccagag
     2101 attttatctt tatcctgatt ttgttaggtt tcatccttgt tgtgaccctc ttattactgg
     2161 aaaatagacg tgataatatt cagttgaagc aaatcaatca aaaggttaaa gatttgattg
     2221 caggagatta ttccaaggtt cttgatatgc aaggtgggtc tgaaatcacc aatattacca
     2281 ataatttgaa tgacttgtcg gaggttattc gtctcactca ggaaaatcta gaacaagaga
     2341 gtaagaggct aaatagtatt ctgttttata tgacagatgg ggttcttgcg accaaccgtc
     2401 ggggtcagat tatcatgatt aacgatacag ccaagaagca actggggttg gttaaggaag
     2461 atgttctgaa tagaagcatt ttggaattgc tcaagataga agaaaactat gaattgcgtg
     2521 atttgattac ccaaagtcca gaattgttgc tagattccca agatatcaat ggcgaatatt
     2581 tgaaccttcg agttcgcttt gccttgatac gtcgagagtc tggctttatt tcaggtttgg
     2641 tggctgtttt gcatgatacg acggagcagg agaaggaaga acgcgaacga agactctttg
     2701 tttccaatgt tagccatgag ttacggactc ctctgactag cgtaaaatcc tatcttgaag
     2761 ccttggatga gggggctttg tgtgaaactg tagcaccaga ctttatcaag gtttctcttg
     2821 atgagaccaa ccgtatgatg cgcatggtga cggatctcct ccatctttca cgtattgata
     2881 atgctaccag tcacctagat gtggaactga ttaacttcac tgcttttatt acctttatcc
     2941 tcaatcgttt tgacaagatg aaaggacagg aaaaggagaa aaaatatgag ttggtgagag
     3001 attatcccat caattctatc tggatggaaa ttgatacaga taagatgacg caggttgtcg
     3061 acaatatttt aaataatgct attaagtatt cgccagatgg gggtaaaatc actgtcagaa
     3121 tgaagacaac tgaagaccag atgattttat ccatttctga ccacggtttg gggattccta
     3181 agcaggattt accacgtatc tttgaccgtt tctatcgtgt ggatcgtgct agaagtcgtg
     3241 cacaaggtgg tacaggtcta ggactgtcta tcgctaaaga aattatcaaa caacataagg
     3301 gctttatttg ggccaagagt gaatacggca agggttcaac ctttaccatt gtgctccctt
     3361 atgataagga tgcagtgaaa gaagaagtat gggaggatga agtagaagac tagaatgagt
     3421 gaaataggct ttaaatacag tattttagcg tcgggttcca gtggaaattc tttttatctg
     3481 gaaacctcaa aaaagaagct tttagtagat gcaggcttgt ctggcaagaa aattaccagt
     3541 ctgctagctg aaattaaccg taagccagaa gacctggatg ccatcttgat tacccatgag
     3601 cattcagatc atatccatgg agtaggcgtt ttggctcgca agtatggtat ggatctttat
     3661 gccaatgaaa agacctggca agctatggaa aatagtaaat atcttggcaa ggtggattct
     3721 tcgcaaaagc atatttttga aatgggtaaa accaaaacct ttggagatat cgacatcgag
     3781 agttttggtg taagccatga tgcagtcgca ccgcagttct atcgctttat gaaggatgat
     3841 aagagttttg tcctcttgac agatacaggt tatgtcagtg accgtatggc gggcattgtc
     3901 gaaaatgcgg atggttatct tatcgaggcc aaccatgatg tagagatttt gcgatcaggt
     3961 tcttacgctt ggcgcctcaa acaacgaatc ctatctgacc ttggtcacct ttctaacgag
     4021 gacggtgctg aagctatgat tcggacgcta ggaaatcgta ctaagaagat ttaccttggg
     4081 catttatcta aggaaaacaa tatcaaggaa ctggctcata tgaccatggt caatcagctg
     4141 gctcaagctg atctgggagt cggagtagac tttaaggttt atgatacctc accagatacc
     4201 gcaacaccat tgacagagat atagaaagaa cgctgagaag gtgttctttt tatattgact
     4261 ggacacctaa aaagtaatac aatggtgtta ccattaaaaa agggagcaca aaagatgact
     4321 actattacat taaaagtttc tgaagctgat aaaacattta tgaaagcaat ggctaagttt
     4381 gaaggagttt ccctttcgga acttattcgc accaaaactc ttgaagccct agaagatgaa
     4441 tacgatgctc gtgtggcaga tttagcctat caagagtatt tagaagactt ggaaaaagga
     4501 gttgaaccca ttacttggga agaaatgatg catgatttag gcttgaagga tgaataattt
     4561 gtataaatta gttccaacaa gacgttttat caagcaattg aaaaaattgg accgttatac
     4621 gcagaagcta attacaaact atttacaaac caatgttttg gaagatccaa gacgacacgg
     4681 aaaggctttg gttggtaatc gcgttggtca atggcgctat agaattggta attatcgagt
     4741 tatcgtacaa attgtagatg atgaattagt tgttgctact ctagaagttg gtcatcggag
     4801 agatatttat taaattaaag ctgagtaata acagtataga aagtaaggag agtaaaaatt
     4861 tgaagaaaaa atggtttttt gcagattatt atgacacaac aattatttta cttgctttaa
     4921 tctctgttat tctggtatta cttggatttg ctgagatgat tgatttggac aatccgcctt
     4981 atagtattat tgatttagta atctggggtg tttttgtaat tgattatagt tggcgctttt
     5041 ttacgactaa aagaaaatgg cgctttattc ttgaaaatat ttttgattta ttggctattc
     5101 tccctttaaa tgctattttt acagtgtttc gattagggcg tatctttcgt ttagctaaac
     5161 taacaaaatt actgaaactg actcgtttac ttagaataat tggacttaca ggtaaattag
     5221 aaagaaaaat tagtagattc ttacggacaa atggcctgat ttatatcttg tatgttaata
     5281 tctttattgt tctagtaggg agttcgattt tatccgttgt tgaagaaaaa tccttctcag
     5341 atagtctttg gtgggctctt gtgacagtaa ctactgttgg atatggggat attgttcctg
     5401 cttccatttt tgggaaatgg ctagcagttt tactgatgct tgtcggtatt ggaacaatag
     5461 ggatgttaac aagtgctttg acgaactttt ttgtaaagga taatccagat gaacagataa
     5521 aacttgataa actcaaagat gaattatcga gccaaagaat attactagag aaacaatcta
     5581 aaaagataga agaactacat aaaatgatac aagatttgat tgaaaaaaca taataaaaat
     5641 aaagatgaga caaagtttga gctgaggaga aatcaagtaa gttttgacac aatagaacgc
     5701 atattatcag gtataaaaac ttgatactat gcgttttata gagaaataaa ataaaatctg
     5761 aacaaatcaa ttaggaattt aaagcatttt ataacaacgt tttagagtga tggggtgcta
     5821 tttcaacttc aacctactat aatacagaaa aaaacaactc cctgatgatt caaggagttg
     5881 tctatagtta aattagtttt tagaagcttc ttggaattct ggatttttcc atgcttcgtc
     5941 aataatagct tgcaattctt tagcagatgc ttgcattttt tgagtttctg catcgttcaa
     6001 tggaatgttt actggacgaa cgataccatg tgcaccaaca acagctggtt gaccgataaa
     6061 gacattctca actccgtata gaccttcttg gaatactgaa agtggaagta ctgcgttttc
     6121 atcgtcaagg attgctttag tgatacgagc aagggctact gcgataccgt agtatgttgc
     6181 accttttttg ttgatgattg tgtaggctgc atcacgaaca ccttcgaaca attcaatcaa
     6241 ttcagcttct tgaacatttt gagtgtcttt aaggaattct tcaaggttta caccagcgat
     6301 gttagcgtgt gaccaaacag cgaactcaga gtcaccgtgt tcacccatga tgtaggcgtg
     6361 cactgaacga gcatccacat ccaatttttc agcaagtgct tgacggaaac gagctgagtc
     6421 aagtgaagta cctgaaccga taacgcgttc tttagggaaa ccagagaatt tccaagttga
     6481 gtaagtcaaa acgtcaactg ggttagcagc aacaaggaag atacctttga aaccagattc
     6541 aacaacttga gttacgattg atttgttgat agcaaggttt ttacctacaa ggtcaagacg
     6601 agtttcacct ggtttttgag gtgcacctgc agtaatcaca acaaggtcag cgtctgcaca
     6661 gtcagagtat tgagctgcat agattttttt aggtgaagtg aaggcaaggg cgtgactaag
     6721 gtcaagcgca tcaccaacag ctttttcatg caattgtgga atttcgataa ttccaagctc
     6781 ttgtgcaatt ccttggttaa caagtgcaaa agcgtaagat gaacctacag caccatcacc
     6841 gacaaggata acttttttgt gttgtttagt tgaagtcatt gttttaaaca tctccttaat
     6901 tttattaggg gattttccct agacaacttc attctatcac ttttaaaaaa ctttgtcacg
     6961 aatatgcctt atagttctcg atgtaaacgt tttagtggtt tagaggctga aatagatggg
     7021 aatttatggt ataatgttgt tacttactaa ttgtgaaatg aggcatttat taatgcagga
     7081 taaaaattta gtgaatgtca atctgacaaa ggagatgaag gcaagtttta tcgactacgc
     7141 catgagtgtt atcgtagcgc gagctcttcc tgatgttcga gatggcttaa aacctgttca
     7201 ccgtcgcatt ctctacggaa tgaatgaatt gggtgtgacc ccagacaaac cccataaaaa
     7261 atctgctcgt attacagggg atgtcatggg taaatatcac ccacacgggg attcctctat
     7321 ttatgaagcc atggtccgta tggctcaatg gtggagctac cgttacatgc ttgtagatgg
     7381 tcatgggaat tttggttcca tggatggaga tagtgctgcc gctcaacgtt ataccgaggc
     7441 acgtatgagc aagattgctc tggaaatgct tcgtgatatc aacaaaaata cagttgattt
     7501 cgttgataac tatgatgcca atgaacggga acccttggtc ttgccagcgc gttttccaaa
     7561 ccttttggtt aatggagcaa ctggtatcgc ggttgggatg gcaaccaata ttccacctca
     7621 taatctgggt gaaaccattg atgcagtgaa gttggtcatg gataatcctg aagtgactac
     7681 caaggacttg atggaagtct tgcctggacc agattttcca actggtgctc ttgtcatggg
     7741 gaaatcaggt atccataagg cttatgaaac aggtaaaggt tcgattgccc tacgttctcg
     7801 tacagagatt gaaacgacta agactggtcg tgagcgcatc gttgtaacag aatttcctta
     7861 catggtcaat aaaaccaagg tgcatgagca tattgttcgc ttggttcagg aaaaacgcat
     7921 tgagggtatc acagcagtac gtgatgagtc aaaccgtgaa ggtgttcgat ttgttattga
     7981 agtcaagcgc gacgcctcag ccaatgttat tctcaataac ctcttcaaaa tgacccaaat
     8041 gcaaaccaat tttggtttca atatgctcgc tatccaaaat ggtataccga aaattttgtc
     8101 tcttcgtcag attttggatg cttatatcga gcaccaaaaa gaagtggttg ttcgtcgtac
     8161 acgttttgat aaggaaaaag cggaagcgcg cgctcatatc ttagaaggtc tcttgattgc
     8221 gctagaccat atcgacgaag tgattcgtat catccgtgct agtgaaacgg atgcggaagc
     8281 tcaagctgag ttgatgagca agtttaagct ttctgaacgt caaagtcaag ctatccttga
     8341 tatgcgtctt cgtcgtttga caggtttgga acgcgataag attcaatctg agtatgatga
     8401 cctcttggct ctgattgcgg atttagcaga tattcttgct aagcctgaac gtgtttctca
     8461 aattatcaaa gacgaattgg atgaagttaa acgtaaattt tctgataagc gccgtacaga
     8521 gttgatgatt ggacaggtct tgagtctcga ggatgaggac ttgattgaag aatcggatgt
     8581 cttgattacc ctttctaaca gaggctacat taagcgtttg gatcaggacg agttcactgc
     8641 tcaaaaacgt gggggtcgtg gtgtccaagg aacgggagtg aaagatgatg actttgttcg
     8701 tgagttagtg tcaactagca cccatgatca tctgctcttc ttcacaaaca agggacgtgt
     8761 ctatcgtctt aaaggttatg aaattcctga gtatggtcgg actgccaaag ggctaccagt
     8821 agtcaatctc ttgaaattgg atgaagacga aagtattcag acggttatca atgttgagtc
     8881 tgatcgcagt gatgatgctt atctcttctt tacaacccgt cacggtattg tgaagagaac
     8941 cagtgttaag gagtttgcca atattcgtca aaatggtctc aaagcgctga atttaaagga
     9001 tgaagatgag ttaatcaatg tcttgttggc agaaggagat atggatatta tcattggtac
     9061 caagtttggt tatgcagttc gctttaatca atcagccgtt cgtggtatga gtcgtatcgc
     9121 cactggtgtg aaaggtgtta accttcgtga aggagacaca gttgttggtg ccagcttgat
     9181 tactgatcaa gatgaggttc ttattatcac agaaaaagga tatggtaagc gtacagtcgc
     9241 tactgaatac ccaacaaaag gtcgtggtgg taagggaatg cagacagcta aaattaccga
     9301 aaaaaatggc ttgctggccg gtcttatgac tgttcaaggg gatgaggatt tgatgattat
     9361 cactgataca ggtgtcatga ttcgaaccaa tcttgccaat atttcacaaa caggacgtgc
     9421 aactatggga gttaaagtaa tgcgcctgga tcaagatgct cagatagtga ctttcacaac
     9481 ggttgcggtg gcagaaaaag aagaagttgg gacagaaaac gaaacagaag gtgaagaata
     9541 atgtctcaaa aaaataataa aaagaaaaac aagcgaaaaa atctgctgac aaatatccta
     9601 gcaggatttc tgatattact gtcactggct ttgattttta atactcaaat tcgaaatatt
     9661 ttcatagtct ggaataccaa taagtatcaa gttagccagg tatcaaaaga aaaattagaa
     9721 gaaaatcagg atacagaagg caattttgac tttgattctg tcaaagctat ctcttcggaa
     9781 gctgttctaa cttctcaatg ggatgctcaa aaattaccag ttattggggg aattgcaatt
     9841 cctgaattgg aaatgaattt gccgattttt aaaggacttg ataatgttaa tctcttctac
     9901 ggagctggta caatgaaacg cgagcaagta atgggagaag gaaattatag tctagctagt
     9961 caccatatct ttggtgttga taatgctaat aaaatgttat tttctccttt agataatgct
    10021 aaaaatggca tgaagattta tctaaccgat aaaaataaag tttatactta tgaaatacgt
    10081 gaagtcaaac gtgtgacacc ggatcgtgtt gatgaagttg atgatagaga tggggtcaat
    10141 gaaatcacat tagtaacctg tgaagacctt gctgctacag aacgtattat tgtcaaaggt
    10201 gatttgaaag aaacaaaaga ttattcacaa acatctgatg aaattctaac agctttcaat
    10261 caaccatata aacaatttta ttaatacaaa tcagtgaaat catggatttc actgattttt
    10321 taagattttc ataaaaatat agtaaaatga aataagaata ggacgaatcg ttcaggacag
    10381 tcaaatcgat ttctaacaat gttttagaag tagaggtgta ctattctagt ttcaatctac
    10441 tataaacttt tatgaaatac agaaaacgct tcctaaaacc taaagtttgt gatataatta
    10501 tcaagaaaaa agatttagga gtttattatg gtttcttcag aatttatctc aaagattgaa
    10561 tttgcttgca ataagaaaga aagtctttat agtcaaagca aatttaagta tgcgattcgt
    10621 tcgatgttcg caggtgcatt tttaaccttc agtactgctg caggtgcagt tggggctgac
    10681 ttgattaata aaattgcacc aggtagtgga cgcttcctct ttccattcgt ttttgcttgg
    10741 ggcttggcct acattgtttt tttgaatgcc gagttggtca cttcaaacat gatgttcttg
    10801 actgctggta gtttcttaaa aaaaatctct tggagaaaaa cagctgagat tttactatac
    10861 tgtaccttgt tcaaccttat cggagccttg atagcagggt ggggctttgc tcattcggca
    10921 gcctatgcga atctgacaca cgatagtttc atctcaggtg ttgttgagat gaagttaggc
    10981 cgctcaaatg aattggtctt gcttgaggcg attttggcaa atattttcgt aaatattgcg
    11041 attctgtcat ttattttggt caaagatggt ggtgccaaac tttggcttgt gttgtcagct
    11101 atttacatgt ttgtattctt aacaaacgag cacattgcgg cgaactttgc ttctttcgcg
    11161 attgtgaaat tcagtgttgc tgcggattca attgccaact tcggtgttgg aaatatgctt
    11221 cgccactggg gtgtgacttt catcggaaac tttatcggag gaggcctctt gatgggtctt
    11281 ccatatgcct tcctcaataa aaacgaagat acttatgtag attaagaaaa tgagcacgat
    11341 tgagtcgtgc ttttttcatt ttcaaaataa ggtaatagct atttcttata tcaaaatata
    11401 gaaaactgat atttgtaaac tataactcaa ggtgctacaa tatccttaat aaaatgatat
    11461 ggaggtcacc ttatgacttg tgattttaaa tttgaaactc tacaactaca tgctggtcaa
    11521 gttgtggctc cagctactaa gtctcgtgca gtgccgattt atcaaacaac atcttttatt
    11581 tttgatgaca cgtaggaagg tgctgatctg tttgccttga ggaaaccagg gaacatttat
    11641 actcgtatca ccaatcctac aacagctgcc cttgaaggtg gtgttgaagc gctagcaaca
    11701 gcatcaggta tgactgcagt gacttatacg attttggcgc ttgcccatgc tggtgaccat
    11761 gtagtggctg cttcgactat ttacggtgga accttcaatc ttttgaaaga accccttcct
    11821 cgttatggta tcacaacaac ctttgtcgat gttgataatt tggaggaagt agaagcagct
    11881 atcaaagaca ataccaagct tgtcttgatt gaaaccttgg gtaactcctt gattaatatt
    11941 ccagacctgg aaaaactggc agagattgct cataaacatc aaatcccact tgtgtcagac
    12001 aatacttttg caatacctta tttgattaac gtcttctctc atggcgttga cattgccatt
    12061 cactctgcga ctaagtttat cggtgggcat ggtacaacta ttggaggaat aattgtcgat
    12121 agtggtcgtt ttgactggac ggcttcaggg aaattccctc aatttgttga cgagggtcca
    12181 agctgccaca atttgagtta tacttgtgat gtgggtgcag cagcctttat tatagctgtt
    12241 cgagttcaat tgcttcgtga tacaggtgca gccttgtcac cattcaatgc tttcctcttg
    12301 ctacaaagac ttgaaacctc ttcacttcgt gtggaacgcc atgtacaaaa tgctgagaca
    12361 attgttgatt ttcttgtcaa ccatcctaag gtagaaaagg taaattatcc aaaacttgca
    12421 gatagtcctt atcatgcctt ggctgagaaa tacttgccaa aagatgtcgg ttcaatcttt
    12481 accttccatg tcaaaggtgg cgaggaagaa gcacgcaagg tcattgataa tttagaaatc
    12541 ttttctgacc ttgcaaacgc ggcagatgct aaatcgcttg ttgtccatcc agcaacaacc
    12601 actcacggtc aattgtcaga aaaagaccta gaagcagcag gtgtcacacc aaactaaatt
    12661 cgtttgtcaa tcggtcttga aaatgtagaa gatttgattg aagacttgcg cttggccttg
    12721 gaaaaaattt aaagtaaaag aagataaaca gtgggcttcg actcactgtt tttgattttc
    12781 cctcaggcat gatataatgg ttaaagaagt ctagaaagag gaacgatatg aacgaaatca
    12841 aatgtcccaa ctgtggggaa gtctttacag taaatgagag tcagtatgcc gaactcttgt
    12901 cccaagtgag aacggcagag tttgataagg aactacacga taggatgaag caggaactgg
    12961 ccttggctga gcaaaaggcc atgaatgagc aacagactaa actggctcag aaggatcaag
    13021 aaattgcgca attacagagt cagatccaaa actttgatac agaaaaagaa ttggccaaga
    13081 aagaggttga acagacaagc catgaggctc tcttggctaa ggacaaggaa gtacagctct
    13141 tagaaaatca gttggctacc ttgcgtttgg agcatgaaaa tcaactgcaa aagacccttt
    13201 ctgacctaga aaaagaacgg gatcaggtta aaaaccaact acttttgcag gaaaaggaaa
    13261 atgaattatc tttggcttct gttaagcaaa actacgaagc ccagctcaag gcagctagtg
    13321 aacaagtcga gttttataag gattttaagg ctcaacaatc tacaaaagcg attggggaaa
    13381 gcctagaaca gtatgcagag agtgagttta acaaggttcg tagtttcgcc tttccaaatg
    13441 cttactttga gaaggataac aaggtctctt cgcgtgggtc taaaggggac tttatcttcc
    13501 gtgagtgtga tgaaaatgga gttgaaatca tttctatcat gtttgagatg aaaaacgaag
    13561 cagacggaac agagaagaag cacaagaatg cagattttta caaggaattg gacaaggacc
    13621 gtcgggagaa gaactgtgag tatgccgttt tggtgaccat gcttgaggcc gataatgact
    13681 actttaacac agggattgtt gacgtcagcc acgagtatga aaaaatgtat gttgttcgtc
    13741 ctcaattctt tatccagttg attggtctct tacgtaatgc ggcgctaaat tccctaaaat
    13801 acaagcagga gttggccttg gttcgcgagc aaaatattga cattacgcat tttgaggaag
    13861 acttggatgc ctttaagcta gcttttgcta agaactataa ttcagcttcg actaactttg
    13921 gaaaagctat tgatgaaatc gacaaggcca tcaaacgcat ggaagaggtt aagaaattcc
    13981 tgactacatc tgaaaaccaa ctccgtctag ctaacaacaa attggaagat gtctctgtta
    14041 aaaaattgac ccggaaaaat ccaacaatga aagcgaagtt cgaagcactg aagggggagt
    14101 agaaagcaaa aatgaacggt attatcaact taaaaaaaga agcaggaatg acctcgcatg
    14161 atgcggtttt taaactgcgt aagattttgg gaaccaagaa aattggtcat ggtggaacct
    14221 tggatccgga tgtggtgggt gttttgccga ttgcggttgg caaggcgaca cgcatggtcg
    14281 agtttatgca ggacgagggt aagatctatg agggggaaat cattctgggc tattccacga
    14341 cgactgagga tgctagtggg gaagtggtcg cagaaacccc tgttttgtct cccttggatg
    14401 aaaagcttgt tgatgaagcg attgctagct tgactgggcc tattactcag attcccccta
    14461 tgtattcggc agttaaggtt aatggtcgca agctctatga gtatgcgcgt gctggtcagg
    14521 aagtggagcg tccagaacgt caggtgacca tttatcaatt tgagcgaaca agtccgattt
    14581 cttatgatgg ccaacttgcc cgattcactt ttcgtgtaaa atgcagtaaa gggacttaca
    14641 tccgtacttt gtcagttgat ttgggtgaaa agcttggtta tgcggctcat atgtcccatt
    14701 tgactcgtac tagtgctgct ggcttacaat tagaagacgc tcttaccttg gaggaaattg
    14761 ctgaaaaagt agaggctggg caattagatt ttctccatcc tttagagatt gggacaggtg
    14821 accttgtcaa agttttccta actccagaag aggctacaga agttcgcttt ggtcgtttta
    14881 ttgagctaga ccaaacggac aaagaactgg ctgcctttga agatgataaa ttgttagcca
    14941 ttctagaaaa acggggcaat ctctataagc caaggaaggt ttttagctag atcgtttagg
    15001 aataaaaatc gggtgataga taacaattgc ttgataaacc cccatactaa tagtagaatg
    15061 gttttgggaa ttataatatt ccaattgttg cgagttgtag atactcaaat aatctatata
    15121 gaaatttaga ggtgtgaaat gaagcaactt aaaattcttt cagataaata tttagagtcc
    15181 atgacaggtt ctggtgggaa cttaggtcta ggatttggtg tgataattcc atgatgtgaa
    15241 atgagtttcg agaaagggtg gagcaacttc ttcaacaaaa agaaataaat gaaaatagtg
    15301 agttgagtca cctgtttcgt cttgctatac aaaatttaga cagaaatgaa aaataccaat
    15361 cggtcatggc caatttgagt caagggttgt cactttacct catgacgcat cattaccagg
    15421 cacctaagtc tgtcattgat tttggtttat ggattgccaa agctcctagc caggaaagag
    15481 ggagactggc tttcttgcag atgcttgctc aaaccctaca gggctttcgt taaaactgtc
    15541 gaacatcaga gggaagactc tggtgttttt tgctgatgag actataaatt ttgtaaaaaa
    15601 tgtgatagaa tagacgacgg ataaaataac ggaggatagc atgcaaaata gaccaatcat
    15661 tattggagtg acaggtggtt ctggtggtgg taaaaccagt gtttcaagag ccattttatc
    15721 gcattttcct gatgaaaaga tttccatgat tgagcatgat tcatactaca aggatcagtc
    15781 tcatttgacc tttgaagagc gtgtcaaaac caactatgac catccttttg cctttgatac
    15841 agacttgatg atcgagcaga ttaaggaatt gttggcaggg cgtccggtgg acatcccgac
    15901 ctacgactat acagagcata cacggagtag caagacctat cgtcaggagc ctcaagatgt
    15961 ctttatcgtt gagggcattt tggtcttgga ggacaagcgt ctgcgcgatt tgatggatat
    16021 caagattttt gtggatacgg atgacgatgt gcgtattatt cgtcgtatca agcgtgatat
    16081 ggaggaacgt ggccgtagcc ttgatagcgt tattaaccag tacttaggtg tggtcaaacc
    16141 aatgtaccac cagtttatcg agtcaactaa gcgttatgct gatatcgtca ttcctgaagg
    16201 ggttagcaat accgtggcta tcgacctgtt gacgaccaag attgcaaaga ttttggaaga
    16261 agctcgaaac agcaaataat cacatgtgga ggccttgcct cctttttcta tttttccctc
    16321 ataatggtac ataaatggag atttttaggc atatttttgg tataataata cccataaaag
    16381 agcaagtaaa tgaatagtag gtggagatgg aaaagtattt atcggtaaca actttgacca
    16441 aatatctgaa aatgaaattc gataaagacc catacttgga acgggtctat ttaactggtc
    16501 aagtttccaa ctttcgtaaa cgacctactc accaatattt ctccctaaag gatgaccatg
    16561 cagttattca agcgaccatc tggtctggga tttatcagaa attagggttt gacctggaag
    16621 aaggaatgaa gatcaatgtg attgggcgtg tacaggtcta tgaaccaagt ggtagctact
    16681 ccatcatcat tgaaaaagct gagcctgatg gggttggggc gcttgcgatt cagtttgaac
    16741 aacttaagaa aaaattgaca gaagaaggcc tgtttcaaga acgcttcaag caagctctac
    16801 cccaattttc taagagaatt ggggtagtaa ccagccgtag tggagccgtt attcgagata
    16861 ttatcacgac cgtcagcagg cgattcccag gtgttgacat ccttctttat cctaccaagg
    16921 ttcaaggtga aggggctgcg gaggaaattg ctagaaatat tgcgcgtgct aatcaacggg
    16981 acgatttgga tttgctcatt attggtcgtg gaggtggttc tattgaggat ctctgggcct
    17041 ttaacgaaga aattgtggta cgagctattt ttgaatctcg tttgccagtt atctctagtg
    17101 tggggcatga gacggatgtg accttggcag attttgtggc agatcgacgc gctgcaacgc
    17161 caacagcggc ggctgaactg gcaacacctg tgaccaagtt ggatgtatta gctcatttgc
    17221 aaaatcagga aaaacggatg gcaacggcag tccgaaatgt tctatctaag aaacaagagg
    17281 ctttgaaaaa atgcagtcag tctgttatct ttagacaacc tgagcgcttg tatgacggtt
    17341 atttgcaacg cttggaccaa ctgcaactgc gtttgaaaca aagtttgcga actcggattt
    17401 ctgataacaa acaattagtt caagcaagaa ctcatcaatt agtacaatta tcacctgtta
    17461 ccaaaatcca acgctatcaa gaccgtttag gacagttgga caagctctta ggtagccaaa
    17521 tggcgttagt ttatgacgcc aaggttgctg aggccaagcg actttcggaa gctttgctca
    17581 tgttggatac tagccgaatc gtggcgcgtg gttatgctat tgtcaaaaaa gaagagtccg
    17641 ttgtagattc ggttgagagt ttgaagaaaa aagaccaagt aacgcttttg atgcgagatg
    17701 gtcaagtaga attagaggtt aaagatgtca aaacaaaaga aatttgagga aaatctagca
    17761 gaactggaaa ccattgtcca aagtttggaa aatggtgaaa ttgctctgga agatgcgatt
    17821 actgcctttc aaaagggcat ggtcttgtca aaagagctcc aagctacgct ggacaaggct
    17881 gaaaagacct tggtcaaggt catgcaagaa gacggaacag aaagtgattt tgaatgaaaa
    17941 agcaagaaaa attagctctt gtcgagtcgg ctttggaaga tttttatgga gaccagcagt
    18001 ttgcctctag tttacgggag tctgttctct attctattca tgctggtggc aagcgtattc
    18061 ggccttttct cttgttagaa gttctggaat ccttgcaggt taccatcaaa cctgctcacg
    18121 cgcaggtagc tactgccttg gagatgattc atacagggag cttgattcac gatgaccttc
    18181 ctgctatgga tgatgacgat tatcgaagag ggcggttaac caatcacaag aaattcggtg
    18241 aagctatggc cattttggct ggagatgcct tattcttaga cccatatgcc ttgattgcgc
    18301 aggcagattt gccaagtcag atcaaggtgg acttgattgc caacttatcc cttgcttcag
    18361 gtagtctggg tatggtggca gggcaagttt tggatatgga gggcgaacac cagcacttgt
    18421 ctctggaaga acttcagact attcatgcca ataagactgg gaagttacta gcctatccct
    18481 tccaagcggc agctattata gctgaattgt cacctgaaat gcaggtgaag ctgaaaactg
    18541 tgggtgaatt gattggactt gcttttcaag tcagagatga tgtactggat gtgacagcta
    18601 gttttgagga aatcggcaag acacctcaaa aggatctgca ggcagaaaaa tcaacctatc
    18661 ctgccttgtt gggcttggaa gagtccattg ccttttgtaa ccaaaccctg gatcaagcta
    18721 atgaaaaatt agaagaaatt gcccagcagc ttccctttga aacagaatcg attgtaagtg
    18781 tagtagaaag tttgagaatc aatggctaag gaaagagtgg atgtactagc ttataaacag
    18841 gggttgtttg aaacgagaga gcaggccaag cgaggtgtga tggctggtct agtcgtagca
    18901 gtccttaatg gagaacggtt tgacaagcca ggagagaaaa ttccagatga caccgaatta
    18961 aaactcaagg gggagaaact caagtatgtc agccgtggtg gtttgaaact ggaaaaggcc
    19021 ttgcaggtct ttgatttgtc ggtggatggc gcgactacga ttgatatcgg ggcctctact
    19081 ggaggtttta ccgatgtcat gctacagaat agtgccaagt tggtctttgc agtcgatgtt
    19141 ggtaccaatc agttggcttg gaaattacgc caagacccac gagttgtcag catggagcag
    19201 ttcaattttc gctatgctga aaagactgat ttcgagcagg agccgagctt tgccagtatt
    19261 gatgtgagtt tcatttccct tagtctgatt ttgccagcct tgcacagtgt cttggctgat
    19321 caaggtcagg tggtagcact tgtcaaacct cagtttgagg caggacgtga gcagattggg
    19381 aaaaatggaa ttattcgaga tgctaagatt catcagaatg tccttgaatc tgtaacagct
    19441 atggcagtag aggcaggttt ttcagtcctt ggcttggact tttctcccat ccaaggtgga
    19501 catggaaata ttgaattttt agcgtatttg aaaaaagaaa agtcagcaag caatcagatt
    19561 cttgctgaga ttaaagaagc agtagagagg gcgcatagtc aatttaaaaa tgaataaaaa
    19621 agaaagactt gaaaaaatta gaagattggt gacagattat caaatcggca cgcaagaaga
    19681 aattgtagaa catttgaaag aagcaggtat cactgccact caggcgacgg tatcccgaga
    19741 tatcaaagag ttaggtattg tcaaaattcc tttgagagac aacacctatg tctacgaatt
    19801 gccaaaatca atcgtaaaaa gtctgcaact ggctgaagac aatatcgaat cggctgaatt
    19861 gatggataag atgatcaatc tccaagttat tccaggaaat acggcttttg taaaagctca
    19921 gttaatcgag acttttgcag acaagatttt tagctgtttg actgatgata gctcgatttt
    19981 agtcattgcc agaagtggaa gtctagcaga ggaaatcttt gaacaagtaa aaaattggta
    20041 ggtctatatg ttacttgaaa tttcgataaa aaactttgcc attattgagg ctatttccct
    20101 caattttgaa aaggggatga ctgtcctgac tggtgaaacg ggtgcaggga agtcgattat
    20161 cattgatgcc atgaatatga tgttgggagc tcgtgcgacg acagatgtta ttcgtcatgg
    20221 tgcaccaaag gcagagattg aggggctttt ctcagttgag aatagtcgtc ttttacagga
    20281 aatttttgat gagcaaggtt tagaattagg tgatgaaatt atcatccgtc gggaaatctt
    20341 gcaaaatggt cgtagtatca gccgtgtaaa tggtcagatg gttaatctgt ctgttttgcg
    20401 aactattggg caacatcttg tagatattca tggtcagcat gaccatgagg agttaatgcg
    20461 tccccaactg catatccaga tgttggatga atttggtgat gccgcttttt gggacttgaa
    20521 agaaacctat caaacgagtt ttgatgccta tcggaaaatg cgcaagcagg ttctggaagt
    20581 caagaaaaac caacaggaac acaaggcacg tatcgaaatg ttggaatttc aaatggcaga
    20641 gattgaggca gcaaacttgc aggctggaga agacttggat ctcaatcaag agcgagataa
    20701 actcctcaac cacaaaaata ttgcggatac actgaccaat gcctacagta tgttggacaa
    20761 tgaagatttt tcaagtctgg ccaatgttcg ttcagccatg aatgacatgg aaagtgtcga
    20821 agagtatgac cctgaatacc gtgaaatttc aagctctctg tctgagacct actatgtttt
    20881 agaagacatt agcaaacgtt tggaagctat cattgaggac cttgattttg atggcaatcg
    20941 cctcatgcag gttgagaatc gtttggacct ccttcatact attactcgta agtatggtgg
    21001 gactgttgat gatgttttgc tttattttgc caagattacg gaagaataca atctcttgac
    21061 aggcaataat ctttcgtctg aggacatgga agcagagctt aagaagttgg aagtcaatct
    21121 tgtcaatttg gcaggtcaac ttgcttctgc tcgtcataat ttggctcagc aactcgaagc
    21181 tgagattaaa caagaactgc aagatcttta tatggaaaaa gcccagtttc aggttcgttt
    21241 tagtaaggga aaattcagtc gtgagggaaa taaaatggtt gagttttata tttcaaccaa
    21301 ccctggagaa gactttaaac ccttggttaa ggttgcttct ggaggggaat tatctcgtct
    21361 catgttagcc attaagtctg ccttttcacg taaagaaggc aagactagca ttgtctttga
    21421 tgaggtggat acgggagttt caggtcgtgt tgctcaagct attgctcaga aaattcataa
    21481 aattggtcag catggtcagg ttttggctat ctcccatttg ccacaagtaa ttgcgattgc
    21541 agattatcaa ttctttattg agaagattag taatgaccat tcaacggttt cgactgttcg
    21601 tctcttgacg gtcgaagagc gagtggagga agttgccaag atgttggcag gtgatgatgt
    21661 gacagaagca gccctgacgc aagcaagaga attgttgaga aacagggaga aataagatga
    21721 cagattatta tgtaattgga gatgttcacg gaaaagctgg gatgctggaa gaccttctca
    21781 aaacctggga tggtcagccc cagttgctct ttctaggtga tttgattgac agaggtgagg
    21841 atagtcaccg tgttcttgaa atggtcaagg acttggtgga caatcaaggg gctatctgtt
    21901 tgtccggaaa ccacgagtat atgtttttga cttggctaga tgacccagaa gaaagttatg
    21961 accattatag tcgcaatggt ggagatacaa ccattaactc tatcctaggt cgtcccttgg
    22021 atgcaccagt tgatggagta gaagatgcca agcgggttgc cgctgaagcg gcagacttgg
    22081 tcgaattcat tcgtcaaatg ccatttgtag tagagacaga caagtatatc tttgttcacg
    22141 caggtattga tttgaccttg gacgactggc atgaaacaac agattataaa aaagtatggc
    22201 ttagaaaacc attccacgga gctgaaaatc atactggaaa aaccattgtc ttcggtcata
    22261 caccggtcta tggtttatta cagcaagaac gcggtacatc tgagctttgg actacagaag
    22321 atggcaagat tggaatggat ggaggagctg tttatggtgg tgtccttcac gggattgtct
    22381 ttacagacca aggaatgaca gaacaccact ttatcgaaaa tgacggcttt gtcgctgaag
    22441 attagtactc ctagcagggt atggtcttgt caaaatatca aaaacaattt ataataaata
    22501 gataccctga aaggaagaga atcatgaact tagaagaatt gaaaaaacga caggagaaga
    22561 tccgtaactt ctctattatc gcccatattg accacggaaa atcaactcta gcagaccgca
    22621 ttttggaaaa aacagagacg gtttcaagtc gtgaaatgca ggcccagctt ttggatagca
    22681 tggagctaga gcgggaacgt ggaattacta ttaagttgaa tgccatcgag ttgaattaca
    22741 ctgcaaaaga tggggaaact tatattttcc acttgattga cacaccaggg cacgttgact
    22801 ttacctatga agtttcacgt tcgctagctg cctgtgaggg tgctattttg gtggtcgatg
    22861 cggctcaagg aattgaggct caaactcttg ccaacgttta tctggctttg gataatgatt
    22921 tggaaatcat gcctatcatt aataaaattg acctgccggc tgcagatccg gagcgcgtgc
    22981 gtacagagat tgaagatgtg attggtttgg atgccagtga agcagttttg gcttctgcca
    23041 aggctggtat tgggattgaa gaaatcctcg agcaaattgt agaaaaagta ccagcaccaa
    23101 cgggtgatgt gacggcgcca cttaaggcct tgattttcga ctctgtttac gatgcttacc
    23161 gtggggttat cctccaagtg cgtgtcatgg acggagtggt caaacctggt gataagattc
    23221 agctcatgag caatagtaag acctttgatg tggccgaagt cggtattttt acaccaaaag
    23281 cggttggtcg tgatttcctt gcgactggtg atgttggtta cattgcggcg tctatcaaga
    23341 cggttcagga tactcgtgtg ggtgataccg ttaccttggc aaccaatcct gcggcagaac
    23401 cattacatgg ttataagcag atgaatccta tggtctttgc gggtctctac ccaatcgaat
    23461 caaacaagta caatgacctg cgtgaagcgc ttgaaaaatt gcaactgaat gatgctagtc
    23521 ttcagtttga accagaaaca tctcaggcac ttggatttgg tttccgttgt ggatttcttg
    23581 gacttctcca tatggatgtt atccaggaac gtttagagcg tgagttcaat attgacctca
    23641 tcatgacagc tccgtctgtt atttacaaag ttaatttgac cgacggtgag tctatggatg
    23701 tgtctaaccc atctgagttt ccagacccaa ctaagattgc gaccattgaa gagccttatg
    23761 tcaaggcgca aatcatggta ccacaggagt tcgtcggagc agtaatggag ctagctcagc
    23821 gtaagcgtgg ggactttgtg actatggact atattgatga taaccgtgtc aatgttatct
    23881 atcaaattcc tcttgctgaa attgtctttg acttctttga taaacttaag tcttcgacac
    23941 gtggttatgc aagctttgac tacgaattgt cagaatatcg cccatctaag ctggtgaaaa
    24001 tggatattct tctcaatgga gataaggtgg atgccctcag ctttatcgtt cacaaggact
    24061 ttgcctacga acgtgggaaa ctcatcgttg ataaactcaa gaaaatcatc cctcgccaac
    24121 aatttgaagt tccaatccaa gcggctattg gacacaagat tgtcgctcgt actgatatca
    24181 aggcccttcg taagaacgta cttgctaaat gttatggtgg tgacgtttct cgtaagcgta
    24241 aactccttga aaaacaaaaa gctggtaaga aacgcatgaa atccatcgga tcagttgaag
    24301 ttccgcaaga agccttcctc agcgtcttga gtatggatga agaataagtt atcagaaatg
    24361 cctttccttg ttcacaggaa atttataaga atcaatagta aagcaggctt agatggtctg
    24421 cttttttagt ttttatactc ttcgaaaatc tcttcaaacc acgtcagcgt cgccttaccg
    24481 ta
//
LOCUS       DAVBIC010000032        24327 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.032, whole genome shotgun sequence.
ACCESSION   DAVBIC010000032 DAVBIC010000000
VERSION     DAVBIC010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24327)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24327)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24327
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.032"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            complement(<1..618)
                     /locus_tag="VQ664_001287"
     CDS             complement(<1..618)
                     /locus_tag="VQ664_001287"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HET2789446.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLA
                     ELGIELEGIINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEK"
     gene            complement(769..2079)
                     /gene="secY"
                     /locus_tag="VQ664_001288"
     CDS             complement(769..2079)
                     /gene="secY"
                     /locus_tag="VQ664_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HET2789447.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            complement(2092..2532)
                     /gene="rplO"
                     /locus_tag="VQ664_001289"
     CDS             complement(2092..2532)
                     /gene="rplO"
                     /locus_tag="VQ664_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HET2789448.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            complement(2677..2901)
                     /gene="rpmD"
                     /locus_tag="VQ664_001290"
     CDS             complement(2677..2901)
                     /gene="rpmD"
                     /locus_tag="VQ664_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HET2789449.1"
                     /translation="MVFQFLIWHKKGDKMAQIKITLTKSPIGRIPSQRKTVVALGLGK
                     LNSSVIKEDNAAIRGMITAVSHLVTVEEVN"
     gene            complement(2873..3367)
                     /gene="rpsE"
                     /locus_tag="VQ664_001291"
     CDS             complement(2873..3367)
                     /gene="rpsE"
                     /locus_tag="VQ664_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HET2789450.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            complement(3385..3741)
                     /gene="rplR"
                     /locus_tag="VQ664_001292"
     CDS             complement(3385..3741)
                     /gene="rplR"
                     /locus_tag="VQ664_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HET2789451.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            complement(3825..4361)
                     /gene="rplF"
                     /locus_tag="VQ664_001293"
     CDS             complement(3825..4361)
                     /gene="rplF"
                     /locus_tag="VQ664_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HET2789452.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEITLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            complement(4553..4951)
                     /gene="rpsH"
                     /locus_tag="VQ664_001294"
     CDS             complement(4553..4951)
                     /gene="rpsH"
                     /locus_tag="VQ664_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HET2789453.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            complement(5236..5505)
                     /gene="rpsN"
                     /locus_tag="VQ664_001295"
     CDS             complement(5236..5505)
                     /gene="rpsN"
                     /locus_tag="VQ664_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HET2789454.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            complement(5523..6065)
                     /gene="rplE"
                     /locus_tag="VQ664_001296"
     CDS             complement(5523..6065)
                     /gene="rplE"
                     /locus_tag="VQ664_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HET2789455.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            complement(6089..6394)
                     /gene="rplX"
                     /locus_tag="VQ664_001297"
     CDS             complement(6089..6394)
                     /gene="rplX"
                     /locus_tag="VQ664_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HET2789456.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            complement(6472..6840)
                     /gene="rplN"
                     /locus_tag="VQ664_001298"
     CDS             complement(6472..6840)
                     /gene="rplN"
                     /locus_tag="VQ664_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HET2789457.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            complement(6866..7126)
                     /gene="rpsQ"
                     /locus_tag="VQ664_001299"
     CDS             complement(6866..7126)
                     /gene="rpsQ"
                     /locus_tag="VQ664_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HET2789458.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            complement(7151..7357)
                     /locus_tag="VQ664_001300"
     CDS             complement(7151..7357)
                     /locus_tag="VQ664_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HET2789459.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            complement(7367..7780)
                     /gene="rplP"
                     /locus_tag="VQ664_001301"
     CDS             complement(7367..7780)
                     /gene="rplP"
                     /locus_tag="VQ664_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HET2789460.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            complement(7784..8437)
                     /gene="rpsC"
                     /locus_tag="VQ664_001302"
     CDS             complement(7784..8437)
                     /gene="rpsC"
                     /locus_tag="VQ664_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HET2789461.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            complement(8450..8794)
                     /gene="rplV"
                     /locus_tag="VQ664_001303"
     CDS             complement(8450..8794)
                     /gene="rplV"
                     /locus_tag="VQ664_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HET2789462.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            complement(8806..9087)
                     /gene="rpsS"
                     /locus_tag="VQ664_001304"
     CDS             complement(8806..9087)
                     /gene="rpsS"
                     /locus_tag="VQ664_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HET2789463.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            complement(9191..10024)
                     /gene="rplB"
                     /locus_tag="VQ664_001305"
     CDS             complement(9191..10024)
                     /gene="rplB"
                     /locus_tag="VQ664_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HET2789464.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            complement(10042..10338)
                     /locus_tag="VQ664_001306"
     CDS             complement(10042..10338)
                     /locus_tag="VQ664_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HET2789465.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            complement(10338..10961)
                     /gene="rplD"
                     /locus_tag="VQ664_001307"
     CDS             complement(10338..10961)
                     /gene="rplD"
                     /locus_tag="VQ664_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HET2789466.1"
                     /translation="MANVTLFDQTGKEAGQVVLSDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            complement(10986..11612)
                     /gene="rplC"
                     /locus_tag="VQ664_001308"
     CDS             complement(10986..11612)
                     /gene="rplC"
                     /locus_tag="VQ664_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HET2789467.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            complement(11828..12136)
                     /gene="rpsJ"
                     /locus_tag="VQ664_001309"
     CDS             complement(11828..12136)
                     /gene="rpsJ"
                     /locus_tag="VQ664_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HET2789468.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            complement(12402..13019)
                     /locus_tag="VQ664_001310"
     CDS             complement(12402..13019)
                     /locus_tag="VQ664_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="HET2789469.1"
                     /translation="MKKKDLVDQLVSEIETGKVRTLGIYGHGASGKSTFAQELYQALD
                     STTVNLLETDPYITSGRYLVVPKDAPNQKVTASLPVAHELESLQRDILALQAGMDVLT
                     IEEPWKASEVLSGAKPILIVEGMSVGFLPKELFEKTICFYTDEETELKRRLARDTTVR
                     NRDASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
     gene            complement(13016..13606)
                     /gene="nrdG"
                     /locus_tag="VQ664_001311"
     CDS             complement(13016..13606)
                     /gene="nrdG"
                     /locus_tag="VQ664_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HET2789470.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVAGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLAQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELPDKDIWSWTGYTWEEMMLETPDKLELLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKEIYEQVKRE"
     gene            complement(13599..14105)
                     /locus_tag="VQ664_001312"
     CDS             complement(13599..14105)
                     /locus_tag="VQ664_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2789471.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKSQSAHDGGFWDVEDFSYEEWL
                     EGNRNKEMGIWLPENRVPSIQFVLFGESGCALGFLNLRLRLNEGLLNYAGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNPASRAVILANGGIFEDARNGVER
                     YWIEVANE"
     gene            complement(14149..14289)
                     /locus_tag="VQ664_001313"
     CDS             complement(14149..14289)
                     /locus_tag="VQ664_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789472.1"
                     /translation="MGKYQLDDKGRAQVTRYHEKHSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            complement(14301..16508)
                     /gene="nrdD"
                     /locus_tag="VQ664_001314"
     CDS             complement(14301..16508)
                     /gene="nrdD"
                     /locus_tag="VQ664_001314"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HET2789473.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKREDYAWK
                     KTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHRLGKEESVDQLFKNCRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
     gene            complement(16628..18166)
                     /locus_tag="VQ664_001315"
     CDS             complement(16628..18166)
                     /locus_tag="VQ664_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HET2789474.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWALHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     FFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVSLGLLVFNLG
                     HRRFAHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLLVFGFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILS
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVVVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            complement(18203..18346)
                     /locus_tag="VQ664_001316"
     CDS             complement(18203..18346)
                     /locus_tag="VQ664_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000956126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789475.1"
                     /translation="MLTKEEVNDMIEFKQTHLHRFREIETFVKLCKKSLKQPSQADNP
                     RTF"
     gene            complement(18424..19956)
                     /gene="cls"
                     /locus_tag="VQ664_001317"
     CDS             complement(18424..19956)
                     /gene="cls"
                     /locus_tag="VQ664_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HET2789476.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGVNLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            complement(20102..20659)
                     /locus_tag="VQ664_001318"
     CDS             complement(20102..20659)
                     /locus_tag="VQ664_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin/fatty acid-binding family protein"
                     /protein_id="HET2789477.1"
                     /translation="MTPLFELVILGELLVRENFSKLVAERKFIMKLKRFTLSLASLAS
                     FSLLVACSQRAQQVQQPVAQQQVQQPAQQPAQQNTNTANAGGNQNQAAPVQNQPVAQP
                     TDIDGTYTGQDDGDRITLVVTGTTGTWTELESDGDQKVKQVTFDSANQRMIIGDDVKI
                     YTVNGNQIVVDDMDRDPSDQIVLTK"
     gene            complement(20656..21906)
                     /locus_tag="VQ664_001319"
     CDS             complement(20656..21906)
                     /locus_tag="VQ664_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HET2789478.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRIQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLADQVKE
                     MEKTLLQTPDQLSFFEMLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLPPEARLVCQKKAESLAVNLYQA
                     GQDFLMLNGDFSSSLLNFSQLNIGLEGVYQQENAALALQTFLLFMGEGKEAVDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGALKRKD
                     YQGMLGYLTEKLPQVELKVTGFDYQGALDERDVTGYDIVSSCREFISSFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            complement(22114..22419)
                     /locus_tag="VQ664_001320"
     CDS             complement(22114..22419)
                     /locus_tag="VQ664_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HET2789479.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            complement(22435..22854)
                     /gene="ruvX"
                     /locus_tag="VQ664_001321"
     CDS             complement(22435..22854)
                     /gene="ruvX"
                     /locus_tag="VQ664_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HET2789480.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPLDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            complement(22858..23124)
                     /locus_tag="VQ664_001322"
     CDS             complement(22858..23124)
                     /locus_tag="VQ664_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HET2789481.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            complement(23211..23780)
                     /locus_tag="VQ664_001323"
     CDS             complement(23211..23780)
                     /locus_tag="VQ664_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET2789482.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGPATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLTIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLAGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSKYISDRLANGATEQ"
     gene            complement(23846..24244)
                     /gene="spx"
                     /locus_tag="VQ664_001324"
     CDS             complement(23846..24244)
                     /gene="spx"
                     /locus_tag="VQ664_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HET2789483.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
BASE COUNT         6740 a         5399 c         4560 g         7628 t
ORIGIN      
        1 tttttcaata tctgagaaga catcattgat atcttgatta ccttcgatgt catgaaccaa
       61 acctttggca cggtagtgag caatgattgg ttctccttga gcaatattaa catccaaacg
      121 acgttttact gtctcaggct tatcatcttc acgttggtag taatcttctt ctttatagtc
      181 aactggtggg ttaaagacct tgtggaaagt ttctccagtt acgcggtgga tgatacggcc
      241 actcaaacgt tccaagaggc tgtcagggtt cacttcaata ttgataatac cttctagttc
      301 aatgccaagt tcagccaatg ttttgtccaa ggcatgagct tgttcaattg tacgtgggta
      361 accatccaat aagaatcctg tttctttaat atcatcttgt gaaaggcgtt cttttacgat
      421 tccatttgta acttcgtcag gaaccaattc acccttgtca atatatgact tagcaagaac
      481 acccatttca gtttgatttg ccattgcagc gcggaacata tcacctgttg agatatgtgc
      541 aacatggaat tgttctacga tttttgctgc ttgagttccc ttacctgcac caggtaagcc
      601 cataatcaaa agattcatga tttgatctcc ttattttatt tttaaataga agcaaaaagt
      661 cttttcaccc ctatttaaaa acaaaataga agaggggaga tccaactctt acaaatgtca
      721 gagtttaaac ctccactccc tcagtattta ctgattcagt aaatactttt attctgttct
      781 gtccatgaaa ccaacatact tacgtttcaa taggtaacct tccaattgct tgattccttc
      841 gatacctgta gagataatga tcaagagact tgttccacca aaggcaacaa catcagaaag
      901 accaaataca tctttagctg caatcggtaa aatggaaatc acaccaagga agagggaacc
      961 aacagttgca agacgacgaa gaagtttaga catatattct tctgtacctt taccaggacg
     1021 aactccatgg atataggcac cactcttttg taggctctct gctgcttttt caggattaat
     1081 ctgtacaaac gtatagaaga atgtaaagag aataatcaac aaagcataca tggcaatacc
     1141 agttggagaa gtagttgcca acatctcttg tgctaccctt acccaagccc aatcatgacc
     1201 tgtggcactc aaaaactgaa gaatagccgc aggcgctgca gtaatcgaac tggcaaagat
     1261 aacagggata actccagcag ggtttacctt taacggaagg taagagctag atggagcacc
     1321 ttgtgcaacc ttagtatatt ggattggaat tttgtattct gcttgttgaa cataagttgt
     1381 aaagtaaata atcaacaata cagtaataat caaaatgatt acgaaaatga tagatgaagt
     1441 gatacggcta cttgggacgt tcacaaagta gtccacatag atgccctgaa tcatctctgg
     1501 aattgaggaa acaatcccgg caaagataat catggaaaca ccgtttccgt atcccttatc
     1561 tgtaatttgc tcacccaacc aagtgacaat catactacca gctgttaaga tgataccaat
     1621 cgtcagaaaa acttgtggag ttaaagcagt tttaatcaat tgagctccag ccaaggtatt
     1681 aaaaccagct gtaatcccga tagattgcac aaaagcgaga actagagcaa tataacgagt
     1741 agcttgattc aattttcttc gacctacttc cccttgttta ccccactcta caaacttggg
     1801 taaaatatcc atttgcaaga gttggacaac aatagaagcg gtgatatagg gactaactcc
     1861 tagggcaaaa atcgaaaagt tttttagggc attccccgac accaagctca acatgtttaa
     1921 gaaggataat ccacttaaag cattcaagct attggcattc acaccaggaa ctgtaatgct
     1981 agttccgata cgaaagacca aaacgataaa aattgtaaat aaaatttttg atcgaacctg
     2041 cttgacttta agagcttctc ttaataattt aaaaaacata ggtcacctct cttagatgac
     2101 ttctactgaa ccacctttag cagtgatagc ttcttcagct gatttagaga atttagctgc
     2161 tttcacagtc aatttcttag tcaactcacc gttaccaaga attttaatac ctgacttttc
     2221 agctttaaca attcctgctt cgataagaac aactggagtt acttcagcac catcttcaaa
     2281 gacgttcaat tggtcaaggt tcacaattgc gtattcttta gcgttgatgt tagtgaatcc
     2341 acgttttgga agacgacgga acaatggagt ttgtccacct tcaaaaccaa ggcgaactcc
     2401 gccaccgcta cgagcttttt gacctttttg accacgacca gatgttttac cgttacctga
     2461 tgaagtacca cgaccaacgc ggttacgtac tttacgagaa ccttctgcag gtttcaattc
     2521 atgaagtttc atttttattt tctcctcttt tgtaaaatgc tagcgccgat aagggagaaa
     2581 aggttgtctc ccccatcaac tcgcctatac gatgtcatca tagatgacta tatctagttt
     2641 taggggatgg tacagtgcac atcccctaaa acttcattag tttacttctt caactgttac
     2701 taagtgagat actgctgtaa tcataccacg gatagcagcg ttatcttctt taataacaga
     2761 gctgttcaat ttgccaagtc caagtgctac aacagtttta cgttgtgatg gaatgcgtcc
     2821 gattggagac ttagtcaaag taattttaat ttgagccatt ttatcccctt tcttatgcca
     2881 aatcagaaac tgaaatacca cgaagggcag caatttcttc agcgcgtttc aattgtttca
     2941 aaccttcaac agttgcacga acaatgttga ttggagtgtt agaaccaagt gatttagatg
     3001 taatatctgc cacacctgcc aattccacaa cggcacgaac tgcaccacca gcggcaactc
     3061 cagaaccttc tacagcaggt ttcaacaata ctttagctcc accgaattct gaaagaactt
     3121 cgtgtgggat tgttgttcca accataggaa cttcgatcaa gtttttctta gcatcatcta
     3181 ctgctttacg gattgcttct ggaacttctt gagctttacc agtaccaaat cctacgcgac
     3241 cattgtggtc accaacaaca acaagagctg cgaaacgaag acgacgtcca cctttaacaa
     3301 cttttgtaac acggttgaca gcaactacgc gttcttctaa ttcaactgca ttgtctttaa
     3361 atgccatttt ctagtgtcct cctattagaa tttcaatccg ttttcacgag ctgcatcagc
     3421 caaagctttc acacgtccgt gatatagata tccaccgcgg tcgaacacca cttctgaaat
     3481 acctttagcg tttgcacgtt ctgcaacgag tttaccgaca gcaacggctt gttcagtttt
     3541 agttcctttt gaaacttctt tatcaagagt tgaagcactt gcgagcgtta cacccgctac
     3601 gtcatcaatc acttgagcgt agatgcctgt attagaacgg aatacgttca aacgtgggcg
     3661 atcagcagtt ccagagagtt ttccgcgaac gcgacggtgg cgtttttggc ggagtttgtt
     3721 tttatctggt tttgaaatca cagttttcac ctctttagtt ttaaatcgtg tgctatgcac
     3781 aaagttggaa aataggttgg tggttgatga tcaaccactc aacattattt acctgtttta
     3841 ccttctttac ggcgaacgaa ttcaccaacg taacggatac ctttaccttt atatggttct
     3901 ggtgaacgaa ggctacgtac gtaagcagct gtttgaccaa ctacttcttt tgaaattccg
     3961 ctaacaacga ttgttgttgg gtttggaagt tcaaaagtaa ttccttctgg agcttcaact
     4021 tcgtctggat gagatttacc aacagccaaa acaagtttag atccttgaag ctgtgcacgg
     4081 taaccaaccc cacgcatttc aagttctttc ttgaatcctt ctgatacacc aacaaccatg
     4141 ttgttcaaaa gggcacgagt agttccgtgg atagttttca tttcttttga atcgtttgga
     4201 cggtgaagag ttatttcagt accttccaca cggatttcaa tatcttttga gaactcacga
     4261 gtaagttctc ctttaggtcc ttttacagtt acaacgttgt cattgttagc gagttcaaca
     4321 ccagcaggca acacgataac tttattacca atacgtgaca tgtttatttt ctcctgttaa
     4381 attgtcaggc cagaacggcc agttttcacg gggttcagat acttatttag ttcaagagct
     4441 gaactgaaca cgctctaaga actgtgcaaa atagataagt tggcttgttt gtaaacaaac
     4501 ttctccaact tcctaatttt gctttgttct ttacgagctt tgtatcttga ttttaccaaa
     4561 cgtaagcgat aacctcacca ccaacattct tttggcgtgc ttctttatca gtaagcaaac
     4621 cttcagaagt tgaaaggatg gcaattccaa gtccgttaag aacttttgga aggtcttcac
     4681 gttttttgta gacacgaagt cctggtttag aaacacgttt caagttagtg ataactttct
     4741 caccatttgg tccgtattta agaaatacac ggatgacgcc ttgtttgtca tcttcaatga
     4801 tttcaacgtt ttttacaaaa ccttcgcgtt taaggatttc agcaatccct tttttgatgt
     4861 ttgatgcagg tacttcaagt acttcgtgtt tagcttggtt agcattacga atacgagtta
     4921 ggaagtctgc gattgggtca gtcataacca ttttgttttt ctcctcttac tagtagtttg
     4981 caagttgcac ttgctagtta atacatgata caaagagcgt aacagcacga gcaaaaatag
     5041 acaatttaat gcagaagcaa tgctccaaag caaattggtc ttttttgcca aagctgtagc
     5101 tcgtgttcaa attggcaagc ccaattgaac ccgggctaaa ctctgtgtga aaaagataaa
     5161 ctttcctaga aactttagtt tcttcgtcaa gtttcctatt tttacttgga gttttgacgc
     5221 tcttgatatc ttaaattacc aagatgcttt tgttacacca ggaatttgac ctttatgcgc
     5281 aagttcgcga aaagcgatac gactcagacc aaatttgcgg taaactgaat gtgggcgccc
     5341 cgtaactcta caacgattat gtaaacgagt cggtgaggcg ttgcgaggta atttagataa
     5401 accttcgtag tcccctgccg cctttaatgc agcacgtttt tcagcataac ggtcaacaat
     5461 tttttggcgt ttagcctctc tagctaccat tgatttttta gccattagat ttacctccta
     5521 tattattttg caaaaggcat tccaaggcct gtaagcaatg cacgtgactc ttcgtcagtg
     5581 ttagcagttg ttacgataac gatgtcaaga ccacgagttt tgtcaacgtc atcgaagttg
     5641 atttctggga agattaattg ttctttcaca ccaagtgtgt agttcccgcg tccatcaaat
     5701 gattttgttg gaacaccgtg gaagtcacgt acacgtggaa gtgaaactga taccaattta
     5761 tccaagaatt cgtacatacg ttcaccacga agggtaactt ttgcaccgat cgcaacacct
     5821 tcacgaagac ggaagccggc gattgatttt ttagctttag tgataagtgg tttttgacct
     5881 gagataagtg ccaattcttc agcagctttt tcaaggcttt tagcgtttga tacagcttca
     5941 ccaacaccca tgttcaaaac aatcttatct actttaggca cagccatcac tgatgagtag
     6001 ttgaattgtt ctgtcaaagc aggaactact tcattaagat atttttcttt taaacgattt
     6061 gccattatac ttctcctttc cttcgtgatt aatcaagcac ttcgcctgat tttttgttgt
     6121 agcgaacttt tttaccgtct acaaatttgt aaccaacacg accagctaca ccatttttgt
     6181 ccaaaacttg aacgtttgat acgtggatag ctgcttcttt ctcgatgata ccaccttgag
     6241 gaagctcgtt agttggacgt tggtgtttct taacaatgtt aacaccttca acgataactt
     6301 tgtttacttt tggaagggca gtaaggacaa cagcttctgt tcccttatct ttaccagcga
     6361 ttacgcgaac tttgtcgcct ttttttacaa acattaggtt tctccttgat ttttcttacg
     6421 cccataaggg caccctagct tgaagctagg ggactagttt gttcctaaaa attaaagtac
     6481 ttctggagca agtgacacga tcttcatgaa gccaccttca cgcaattcac gtgcaactgg
     6541 gccaaagata cgtgttccgc gaggagtttt gtcttcacgg atgataactg ctgcgttttc
     6601 gtcaaatttg atgtatgaac catcagcacg acgagcacct gatttagtac gaacgataac
     6661 tgctttaaca acgtcacctt ttttaaccgc accaccagga gtagcttgtt ttacagatgc
     6721 cacgataaca tcaccgatgt ttgcaaattt acgtcctgaa ccaccaagaa ctttgatagt
     6781 caagatttcg cgagcaccgc tgttgtctgc gactttcaaa cgagtttctg tttgaatcat
     6841 ttcagttttc tcctttcagg tttgattaga tgatgaccgc ttcttcaaca acttctacaa
     6901 gacggaaacg ttttgtagct gaaagcgggc gagtttccat gatacgtacg atatcgcctt
     6961 ctttggcaac attgttttca tcatgagctt tgtatttttt agagtagtta atacgtttac
     7021 catagactgg gtggttacgt tttgtttcaa ctacaactgt gattgtcttg tccattttgt
     7081 cagatacaac acgtccaaca agaactttac gattattgcg ttccattgaa atttctcctt
     7141 ccctagtcta ttatttcgct tcagattgaa ctgttttgat acgagcgatt tgttttttaa
     7201 cttctttcaa gcgagctgtt tgttccaatt gaccagtagc agcttggaaa cgaagttcaa
     7261 acaattcttt tttcaattcg ttttcgcgct tcgcgagttc ttcttgagaa agaccacgaa
     7321 gttctttaac aaattctttt acttcattaa gtttcatgcc ttctccttat tctgcttcac
     7381 gttttacgaa tttacattta actggcaatt tgtggctagc aagtcgaagc gcttcacgtg
     7441 caatctcttc agatacacca gcgatttcga acatcacttt accacgttta actggtgcta
     7501 cccaaccttc aggtgcccct ttaccagatc ccatacgcac accgatagct ttagcagtgt
     7561 atgatttgtg tgggaagatt ttaatccaaa ctttaccacc acgtttcatg taacgagtca
     7621 tggcgatacg agcagcttcg atttggcggt tagtgatcca gtggctagtt gtagcttgaa
     7681 gaccgtattc accgaatgct acttcttttc caccttttgc ttcaccgcgc atttttccac
     7741 ggaactcacg acggtgttta acacgtttag gtactaacat tggttattta cctcctttag
     7801 tgtttttacg agctggaaga acttcaccac ggtagatcca tactttaaca ccaagtttac
     7861 cgtatgtagt atctgcttct tcccaagcgt aatcgatatc tgcacgaagt gtgtgaagcg
     7921 gaacagttcc ttcagagtat ccttcagcac gggcgatatc tgcaccgttc aaacgacctg
     7981 atacttgagt tttgattcct ttagctccag cacgcattgc acgttggatt gcttgttttt
     8041 gtgcacgacg gaaagcaaca cgttgctcca attgacgagc aattccttca cctacaaggt
     8101 gagcatccaa atcaggttgt ttgatttcga tgatgttgat gtgtacttgt tttccagtca
     8161 atttgttaag ttttgcacgg agtgcatcaa cgttagcacc acctttaccg ataaccatac
     8221 ctggtttagc agtgtgaagt gaaacgttaa ctttgtttac tgcgcgttcg atttcaatag
     8281 ttgaaactgc tgcgtcagca agttcttttt gaacgaattt acggattgca agatcttcat
     8341 gaaggtaatc cgcgtattct ttttcagcat accatttggc atcccaatca cggatgatgc
     8401 cgacacgcat accaattgga tgtacttttt gacccacgat tttacctcct tatttttctg
     8461 caacagctac agtgatgtga gctgtacgtt tgttgattgg tgaagctgaa cctttcgcac
     8521 gtggacggaa acgtttcata gttggtcctt cgtttgcgaa tgcttcagat actaccaaat
     8581 tagctttatc caaaccaaag ttgttttcag cgttagctac agctgagttc aaaactttca
     8641 agatgatttc agcagctttg tttggagtga atgtcaagat tgcgattgca tcggctacgc
     8701 ttttaccacg gatgttatca agaacaagac gtgatttacg aggtgaaaca cgtactgtac
     8761 gagccattgc tttagctgaa gtaatttctg ccatttatgt tctccttatt ttctacgtgt
     8821 tttcttgtcg tctgcagcgt gacctttgta agtacgagtt ggtgcaaatt caccaagttt
     8881 gtggcctacc atgtcttctt ggatgtaaac aggtacgtgt ttacgtccgt cataaactgc
     8941 aatagtgtaa ccaatgaaac ttgggaagat cgttgaacga cgtgaccaag ttttaataac
     9001 ttttttcttt tcgtcgttag cttgagcttc aacttttttc atcaaatgct catcgacgaa
     9061 aggtcctttt ttaagactgc gtcccatttt tatattttct cctttaaatg ttgtaccaca
     9121 gcggcttgca ctcctatgga gcgctaccga gctggcggat ttactagttg cttaagcgac
     9181 tagtttaata ttatttctcg ttgcgacgac gaacgataag tttgtcagat ttcgctttct
     9241 tgttacgagt tttaagacca agagcaggtt tgccccatgg agtagatggt gctttacgac
     9301 caactggtgc tttaccttca ccaccaccgt gtgggtgatc gttagggttc attacagaac
     9361 cacgaactgt tgggcggata cctttccaac ggctacgtcc tgctttacca aggtttacaa
     9421 gtccatgttg ttcgtttccg acaacaccaa ctgtagcacg gcaagttcca agaatcatac
     9481 gaacttcacc tgattgaaga cgaacaagaa catatttacc ttcagaaccc aatacttgag
     9541 cagatgcacc agcagcacgt accaattcac caccacgacc tggtttcaac tcgatgttgt
     9601 gaatcaaagt accaactggg atgttagcaa gtggaagagc gtttccgact ttgatatctg
     9661 cttctggacc tgaaacgata cgttgaccta cttcaagacc ttttggagcg atgatgtatg
     9721 ctttcacacc gtcagtgtag tgtacaagag cgatgtttgc agaacggttt ggatcgtact
     9781 cgattgtttt aacaactgct tcaacgttgt ctttattacg tttgaagtca accaaacggt
     9841 aaaaacgttt gtgtccacca ccttggtgac gaactgtgat acgaccgttg ttgttacgac
     9901 cagccttgct cttcaatgca acaagcaatg atttttcagg agtgcttgtt gtgatttcag
     9961 cgaaatccaa agaagtcata ttacggcgac cgtttgttgt tggtttataa acacgaattc
    10021 ccacgatatt tcctccttag attattcagc ttcagcagca aacaactcga ttgctttaga
    10081 atcagctgta agtgtgatga tagctttttt agttttgtta gtaaaaccag tgtaacgtcc
    10141 aacacgttta gcttttggtt ttacgttgat tgtgttaaca ttggcaactt taacaccttc
    10201 gaaagcagct tcaacagctt gcttgatcaa aagtttgtgt gcacgagtgt caacttcaaa
    10261 tacatatttt cctgcttcaa gttgagccat tgagctttca gtgatgacag gttttttgat
    10321 aacatcatac aaattcatta tgcaagaacc tcctcgattt tagagatagc tgcttgtgtg
    10381 acaagaagtt tgtcgctatt tgcgatgtca agaacacttg cagttgtagc agttgcaact
    10441 ttcacgtttg gaaggttacg agctgaaaga gctgcgaatt catttccctc ttcaaggata
    10501 acaagaactt tagaatcgat gctcaatgct gcaagaactt ttgcaaattc agcagttttt
    10561 ggagctgtaa atgaaagagc gtctacagct acgaatttgt tttcagcaac tttttcagag
    10621 taaactgatt taagagctag gcgacgaact ttttgtggaa gtttgtagcc gtatgaacgt
    10681 ggagttggtc cgaagacaac accaccacca cgccattgtg gtgagcggat agaaccttga
    10741 cgagcacgtc cagttccttt ttgacgccat ggtttgcgtc caccacctga tactgcagag
    10801 cggtttttaa cagcgtgtgt tccttgacga aggcttgcgc gttggctgat gattacatca
    10861 aacacaactg attcatttgg ttcgatacca aatactgcat cgctaagaac aacttggcca
    10921 gcttctttac cagtttggtc aaataatgtt acgtttgcca ttgtgactga tttccccttt
    10981 ctttattatt taccagcttt aactgctgat ttgatagtga taagagattt cttagcacct
    11041 ggtacgttac ctttgataag gataacgttc ttttctggaa caacttgtac aacttcaagg
    11101 ttttgaattg ttacgcggtc gccacccata cgccctgcaa ggtttttacc tttgaatacg
    11161 cggttaggtg caacaggtcc catagaacct ggacgacggt ggtaacgaga accgtgagcc
    11221 attggtccac gtgattgtcc gtggcgtttg ataacacctt ggaaaccttt acctttagaa
    11281 gtaccagtta cgtcaacaac gtctccagct gcgaatgttt caactgtaat ttcagcacca
    11341 acttccaagc cttcaacgtt tttgaattca cgaatgaagc gcttaggagc cgtgttagct
    11401 ttcgctacat gtcctttagc aggtttgttg ctcaatactt cgcgtttgtc atcgaaacca
    11461 acttggatag cgttgtatcc gtctgtttca acagttttaa cttgaagaac aacgtttgga
    11521 gttgcttcaa taactgttac agggatcaat tcgccagctt cagtgaagat ttgagtcatt
    11581 cccacttttt tccctaagat tccttttgtc atgagaaaat agttcctttt ctatattttt
    11641 attcaaaaag tttttaacga gcgtttttta tgctcaagtc taagatacaa agggcgtcaa
    11701 actcaacgtg aaaataggaa actgacacag tgtctagcag acgcgaggaa gtttatcttt
    11761 ttcacaccga gtttagcccg tgttcaatta gattgaaaca ccagcctctg ctcttttata
    11821 ttttagatta aagtttgatt tctacgttta caccacttgg aagatccaat ttcatcaagg
    11881 catcaactgt tttttgagtt gggttaacga tatcgatcaa acgtttgtgt gtacgcattt
    11941 caaattgttc gcgagagtct ttgtatttgt gagtcgcacg aatgattgtg tagaggctac
    12001 gttcagttgg aagtgggatt ggacccgcaa cttgtgcacc tgtacgagta gctgattcta
    12061 cgatttttgc agccgctgtg tcaagcgtac ggtgttcgta agctttcaaa cggatacgga
    12121 tttttttgtt tgccatcttt ttctcctttt cgtctattta agataatagg ctagctccac
    12181 aagaaaaccg acgcggtgtt gcgtggcaat gcaaccgagc gtgtcgcaac ctcttgcatc
    12241 aaaactaagg ctgtaattta cagcaccata atagaataac acaaatcccc tgcgattgca
    12301 agggatttgt taggtttttt cgttttttgg ggatgaaact gttttcctac tttttctttc
    12361 taaaattagg gattttcttc tatatttctt ctatacataa gttaagtcct cttgacatca
    12421 aatttatctt ctgattggtc cactaagata tccgccttag actcagtttc tttatagtat
    12481 cgcagatact gctcccgtct catctgatgg ctagccaata taaaggatgc atcgcgattt
    12541 ctcacagtcg tatctctagc aaggcgtcgc tttaattcgg tctcctcatc cgtgtagaaa
    12601 cagatggttt tttcaaagag ttccttgggt agaaagccaa cagacatccc ttcgacaatc
    12661 aaaattggtt tggctccaga caagacctca ctagccttcc aaggttcttc aattgtcaag
    12721 acatccatac ccgcctgcaa ggcaaggata tctctctgca aactctccag ttcatgcgcc
    12781 actggcagac tggctgtcac cttttgattc ggcgcgtcct tgggtactac caaatagcgt
    12841 ccggaggtga tatagggatc tgtttctagc aaatttactg tagtagaatc taaagcttgg
    12901 tacaattcct gtgcaaaggt tgatttacct gaagctccat gaccgtatat tcccagtgtc
    12961 ctgactttcc ccgtctcgat ctctgagact agttggtcta ctaagtcttt tttcttcatt
    13021 ctctcttcac ctgttcatag atttcttttc cgtcattgag cttgtcccaa atcactactt
    13081 gcccactttt gagcgatttt tgcacatcga taattcgttg gttagacgaa cctcgaaact
    13141 ggagcataag atttctctta gttcgatcat atcttccatc gacaagaatg tcaatcagtg
    13201 acaagagttc cagtttatct ggagtttcca acatcatttc ttcccaagtg tagcccgtcc
    13261 aggaccagat gtccttgtct ggcaattcct tccgaatccg cttaacaagt ggcaagagaa
    13321 tcccagtatt aagaaaaggc tcccctccta gtaaggttaa cccctgaaca taaggctggg
    13381 caagatctgc cataatctgt tcttccaact cagctgtata gggaatgcct gcattgaagg
    13441 accaggtcgc tacattataa cacccctcgc agtgaaacat acagcctgct acatagagag
    13501 agttacgcac gccttcgcca tcaacaaagt taaaggcctt gtagtcaatg atacgacctt
    13561 gactaagttc ctcgcttttc cattcttgtg gttttggatt attcattcgc tacctctatc
    13621 caataacgct cgactccatt gcgagcatcc tcaaatattc caccatttgc tagaatgact
    13681 gctctgctag caggattatt cacgctacag gtcaccagag ctttcttgat gttcttttcc
    13741 ttagcaactt gcaagccctg acggagagtc tcttttgcat aacccttgcc tctttcagat
    13801 ggacggatgg agtagccaat gtggccagca taattcagta acccctcatt cagtctcaat
    13861 cgcagattca aaaatcctag agcacaacct gattcaccaa acaatacgaa ctgtatcgat
    13921 ggaacgcgat tttcaggtag ccatattccc atttctttat tacggttacc ttctagccac
    13981 tcctcgtaag aaaaatcctc aacatcccaa aatcctccat catgggctga ttggctcttt
    14041 tcaaactctg tcatcatatc taaaacagct ttcttatccg ctaatcttgg tctgcgtaat
    14101 tccatcctta cctcccacta tgagaaaagc gagagctggc tctcactttt attttttctt
    14161 gttcttgttt aaaaattgtt ctctgaagct aagcaagcgt tctttcttac cagctccacc
    14221 tttagagtgt ttctcgtgat aacgggtcac ttgtgcgcgc cccttatcgt ctagttgata
    14281 ttttcccatt tcatttcttt ctaatttgtt acttgatgcc cagctatttt aatcgttgaa
    14341 ccattcatat gtttgacacg cgcagcgatt tccttgtgac gcccgttgac catcggtctt
    14401 gcttgaggat tacctaggta gccacaagtt cgcttcacca catctactgt tttagggtcg
    14461 ctattgccac agtttggaca agcaaaccct ctctcagttg gttcaaaatc cccttcaaag
    14521 tcacacttgt agcaacggtc aatcggagta ttggtgccta gatagcctac acggtcataa
    14581 gcataatccc agacagcttc caaggccttt ggattttgct gaaggactgg atactcacaa
    14641 taatggatga aaccacctga cgcacctgct tctggataga ctttctcaaa gtccaatttt
    14701 tcaaacggtg ttggattttt acgaacatcg tagtggaaag agttggtgta gtattccttg
    14761 tctgtgatat caggaataga gccaaacttg tctatatcta gtcggcagaa acggtctgtc
    14821 agactttcgg atggtgttga gtagatagag aaatggtagc catattggtc tgaccactct
    14881 tctacacggc gtttcatatc gtgaatgatg tctagcgtga attccttagc atctggatta
    14941 ctttcccagc tgttaccaaa gaaaactgtc gctacttcat acaagccgat atagcccagc
    15001 gaaacggtcg cacgacaatt cttaaagagc tggtcaacac tttcttcttt acctagacga
    15061 tggccaaaag caccgtactg ataaaggata ggagcattcg ctggtgtcgc ctctttagtg
    15121 cgttcgacac ggtaaacaag agcatcttct gcgatattca ttcgctcgtt gaagatttcc
    15181 cagaacttat tcatatcacc ttcagactca agagcaatac gaggcagatt aaccgtcaca
    15241 acacccagat tcatgcgacc tgaattgact tctacaccat tttcatcctt ccatccttgg
    15301 aggaaagaac ggcaacccat aggcaccttg aaggatcctg tcaagtcaac aatcttatcg
    15361 taagataaaa catctggata catccgtttg gttgcacact caagagccaa ctgcttgatg
    15421 tcgtagttgg gagttccttc ctctaaatta aggcctcttt tcagagtgaa aataagttta
    15481 ggaaagatag ccgtacggtg ttctgaacca agacccttga tgcgaatgtt taaaatagct
    15541 ttttgaattt ctcgttcaaa acgactggtt cccagaccaa aacctagcga agtaaaaggt
    15601 gtttgtccat ttgaagtgaa gagagtattg atttcatact caagagattg catggcatcg
    15661 tagatgtcct tttgcgtttt cttccaagcg taatcttccc gtttttcagg caatacccac
    15721 tcttctgcat ctttgagatg tttttgatag ttcttctctg cataaggcgc caaaatttca
    15781 tcgatacggt cagctgaaca gccaccgtac tggctagaag caacgttggc aatgatttga
    15841 gaaatctgtg ctgtcgcagt ctggatagac ttgggactct ctacctctgc atttccaatc
    15901 ttaaaaccat tttccaacat acccttaaaa tcaatcaaac agcagttggt cataggggta
    15961 tagggactgt agtccaaatc gtgatagtgg atatccccct tttggtgggc attggctacg
    16021 tgcttaggaa gcatttgcag tccgattgat ttcccaacaa tccctgctgt caaatcacgc
    16081 tgagtgttaa agacatcact gtctttatta gcattttcat tgacaactgt ctggtctttg
    16141 ttgagaagtt tatgaatact aaagttgata tccgtcgctt ttgagcgctc aaaatccctc
    16201 tgtgtccgat aagtaatata ctcctcagcc agcgcatatt ctttggcttc aaggagttca
    16261 tgttctacga tattttgaat ttcgtaaatc ttaattccct gtggaaagcg actatgaatt
    16321 tctgtaataa ttctctcagt cagatcattg aggcgttttt caaccagggg tgtcacatcc
    16381 ataaccttgt cagctgcctt gtggagagcc ttgtcaatct tgtccacatc aaatacaaca
    16441 cgtctcccat ctcgtttctc gacgaagaga gttggcaaaa ttgtaatttt ttcttctagt
    16501 gcaatcatat gcatgctctt ttctaaaatg ttctttctaa aaagtattat accactctaa
    16561 aaagaaaaat caatatcttg tgttaaaaat cctaaaattt ttaaaaatac acaagatatt
    16621 gatttggtta tttaatttta tagactttaa actctgagta atcagtcttt acttgttggt
    16681 aattttcttt taaaagtgtt tccacttcag accagactac caccttgtca tttaccacaa
    16741 tcaccttagg ttgtttttct ttcaagtcat taagtaactt attacgattt tcctcagttg
    16801 ctgtatagtg caacggggac aaaatcgccg atggcgacaa gcgctcactc ttacgataaa
    16861 gagtcgcagt atcatcccat gcatagatag catcttccgt atttgtctcc tcttttacca
    16921 aatcagcaag acgattacgt tcttgataag gtactggata aaggacaaac ttcatcaaaa
    16981 aaggaacaga caaaagatag acaaacccaa aaactagcag atatagattt cctttgaaga
    17041 aacgactcca taggctaact ggcgtttctc ttcggcttct tctagcacta cgccccctct
    17101 gttgactctt gatattggtt accaataaaa gtaggaaaac agggaagacg accatcaaat
    17161 aagaagcgtg cagaggctct tgtgaaaaga aaagtaaaat caaacctaaa attaccacaa
    17221 gacttgcagg aaccgaaatg acgtatagtt taaagggttt ggattgaaag agacctaaaa
    17281 agatacaaac cacaaatccc aaaccaaggg acaacaagcc ataaaaaaac atattctcta
    17341 aaattttaga agtaaaatca aagcgaatac tgtcaatagg ataacgaata ccactaatcg
    17401 catccccaaa acttcctgtt gcagcactat agtaggcagt tggataaaag acaagtgaaa
    17461 aacctaaagc cactgcaaga aactgataaa acccatgcgc aaagcgtcta tgcccaaggt
    17521 taaagaccaa caagcctaaa ctcactacag caataaacag gagtgatgat aagggagcaa
    17581 agaaaaatcc gcctgccaaa gctaacccaa tccgtacaaa tcccttatca tggcttggat
    17641 tgcttaggta agccgcaact aaactaaagg ctgcgaataa gaaaggaagc gctaaaagag
    17701 tcgcatagcc tccaccaaaa gcaagacctg taactagcat gtaaaaaata gtcaccagat
    17761 gtccagcttg gtctccttgc tctgtcaagg tgtccgctga tctaaaaagg aaaaatcctc
    17821 ctgctaccaa ggctaaccac tcaaagatgg caaagaaaaa tccgccctga ctcacgtaag
    17881 tcagcaaata ataaagcaaa ccttgacttc cataatagtc gctgtaaatc ttccctgtct
    17941 gatgaagcgc ccaacctgca taaaaatcct gcacttcttg tgcactcatt aagtcgagta
    18001 atagcggtac tcctagagtt atccccgtta caagcgtact ccatagtaaa attttcacca
    18061 aaggaagacg acttgattca cgatgatgcg attcttgctc gatttggtat tctagaggtt
    18121 cacgattctc cttatgaact tcttctactc taccatacac actcatatcg tttctcctgt
    18181 tcaatttatc tgtcttagta tatcaaaaag tcctaggatt gtcagcttgc gatggctgtt
    18241 tgagtgattt tttgcatagt ttcacaaagg tttcaatttc ccgaaagcgg tgtaaatgtg
    18301 tctgtttgaa ctcaatcata tcattcactt cttccttagt tagcatgaat tcccctcctc
    18361 tttctttcta ttcgtaaaag acaagaaaaa taggtcgggt ttgtatccta agttctagat
    18421 ttcttataag ataggggcga atagctgggc gatttctttt acaagctttt gataccagct
    18481 cgttttgata gaatgaggat agacttcctg agaatctgca aatatatttc gaaaatctcg
    18541 ggcgatttcc cttatagaag gagttttata gagtaagact gcattttcat aatggtgtac
    18601 caagctccgg tagtcgagat tgattgtccc caccaccgca aaatcttcgt ctaccaacat
    18661 ctgcttacta tgaataaaac ctggactata ctcataaatc cgaacaccag cagaaagaag
    18721 gtcgggataa gctcctctcg tgactaactg aatgaacttc ttatctggta tgtaaggggt
    18781 gataattcga acatcgaccc ctctcatagc tgcatttttg attgtctctg ttaaatcata
    18841 atctataatc aaataaggtg tcgtaatata gaccgattcc gttgcttgat tgattaaact
    18901 ctgataaact tttttcccta cctgcgctcg aaaaattggc ttgggtccac ttccgtatgg
    18961 aatggttaaa ccgtcactcg ggatagaatg attttctaaa tgatattgat caaaatcact
    19021 aatttctcct cgattaatgt accaagtggt caaaaataag cgtgtcaggg cttttactgc
    19081 tagtccgtct aagcgaattc cactatcctt ccaataacca aatctctcga cgtggttaat
    19141 gtactcatct gccagattga ccccaccagt ataggctatc tgaccatcaa caatcaatat
    19201 ttttctatga tctctgttat tataagccac tgtcaaacga ggaataactt tattgaattt
    19261 atgggcctcg atgcccagct gacgaagtcg atgtgcataa tctcctgtta aagtagccat
    19321 acagccgata tcatcataga gcatcttaac ctctacaccc tgagctacct tttgctctag
    19381 tatatctagt atgcgattcc acatcaaacc ttcttctata atgtaatatt ccaagaaaat
    19441 aaatttctca gcctttttaa gatcttctac catctttttc cacatagctt ctccgttagg
    19501 aaaaaatgta gaggcagttt gatcatagat gtcagcattg gtatccatac tcaataagga
    19561 cttgatgact ccataagctg ccttgtcact ttcttttaat ttctctttta gtagctggct
    19621 atttgcttct tggaaatgca tagagcctag cttcttcagt tgtttgattt cttttttgga
    19681 caatcgcctt tcaccaaaca tcagatagag taagggacca aatactggca caaaggctac
    19741 taacaaccag gttaccttat tctcaggagt cgtattacgg ttgactatcg aaatgattgt
    19801 gatgatactc agtagaatga ggacagtaat ccataaaatg ggagccatgc gtcctaaata
    19861 aagaaagaga ccaaaaacaa gacaaagttc aagtagcata atcgaaagac taaagccata
    19921 cttggacatc aataattgaa atttcctata tttcatatcc cctccttgat agtttgaatg
    19981 ctaaaaacaa gtaattgata ctagtataac gcaggtattc ggtagaaggc aagtatttat
    20041 gattattttc taggtaaaag taaaaaggct gaaaaatcca gccctttcta cttgcatagt
    20101 cttatttagt taaaacgatt tggtccgatg ggtctctatc catatcatct acgacgattt
    20161 gattaccgtt tacagtgtaa attttgacat catcgccaat aatcatgcgt tgatttgctg
    20221 aatcaaatgt aacctgtttg actttctgat ccccgtcaga ttcgagctca gtccatgtac
    20281 cagtcgttcc agttaccact aaagtgatac ggtctccgtc atcctgacca gtataagtcc
    20341 catcaatatc ggtcggttga gcaacaggtt ggttttgtac tggagccgct tgattttggt
    20401 tacctcctgc atttgcagta ttggtattct gttgagcagg ttgttgagca ggctgttgga
    20461 cctgctgctg agcaacaggc tgttgaacct gttgagctct ttgtgaacaa gctactaaga
    20521 gactaaaact tgctagagaa gcaagagaaa gtgtgaatct ttttaatttc atgatgaatt
    20581 tcctttctgc taccaattta gagaaatttt ctctaaccag caattcccct agtataacaa
    20641 gttcaaacaa gggggtcaat ttatctgctc acggtccagc aggtagcccc gtacttctga
    20701 gataaaatag agagaccctg taacgaacag caagtcttga gcgtctgccc tttcttcgaa
    20761 actgctgata aattctcggc aagaagaaac tatatcgtaa cctgtcacat ccctttcgtc
    20821 caaagccccc tgatagtcaa agccggtcac cttgagttcc acctgaggca atttttcagt
    20881 caggtaacct aacatccctt gataatcctt ccgtttcaag gctccaaaaa ggatttgagg
    20941 tcgatagcct tcctgctctt tttctttgat aaactcaacc aagcgagtca aggcagggag
    21001 gttatgagca ccatccaagt aaatctgtgg gcgaatacgc tccaagcgac cagcccaatg
    21061 ggtctgttcc aaggcctttc ttacagcctg ttcatcaaca gcttcctttc cttctcccat
    21121 aaaaagaaga aaagtttgca acgccaaggc tgcattctcc tgctgataga ctccttctaa
    21181 gcctatgttc agctgtgaaa aatttagtaa agagcttgaa aaatcaccat tcagcattaa
    21241 aaaatcttga cctgcctgat aaaggttaac agctaaagat tcggcttttt tctgacagac
    21301 aagcctagct tctggaggca atttcgcaat cactgccttc ttaccagcct tgaaaatacc
    21361 agctttctgc tctgcaattg cttctagact atcacccaag gtttcttgat ggtcaagccc
    21421 aatggaggtg atgacagcaa gctctccagt taccacattg gtcgtgtcaa gtaagccacc
    21481 aattcccact tctaataaaa ccaaatccac ctcttgctcc ctaaaataaa gaaaagcaac
    21541 caaggtcagc atttcaaaaa aggacaactg gtcaggagtt tgcagaagcg ttttctccat
    21601 ctccttgacc tgatcagcca aacggataaa gtctgcgtct gctataggtt gcccattaat
    21661 gcagattcgg tcattgatag agacgatatg aggggaggta aaggtcgcaa cttttttgcc
    21721 atgccccata aataattccc tcataaaagc aatggtagat cctttcccat tagtccctgt
    21781 tacgtggata atagggtaag actgctcagg atttcctaac aaatccaccg cttgctgtat
    21841 tcggcccaaa cctgatcgaa aattcaaacc aatccgacta tgaagccatt cttctacttc
    21901 aaacatacac atctccttga caaaagtcca atcaattatc gcattaaagt atggttacta
    21961 ataaaaacaa ggccaggatt ttcgtcccga cctcttacct ggttagctaa taactagcca
    22021 ctatgaatgt gaatatgggc taaaaacatc cactagatgt tccaactctt ccccatttct
    22081 gggagttggg ctgatacagt ctcccagact gtatcactcc tccataaagc tgttgaagac
    22141 ttcttcaatc atgttccatt cgtcttctga gtcttctggg attggttgca attcgccttc
    22201 tgttccatct tcattttcaa tgaatgagta agcttggatt tcaacttgtc cgtcttcgtc
    22261 ttcttctgcg ttaactggta ctagaagaac atagttttta ccaaattctt cttttccatc
    22321 aattgtcaaa aggatttcaa acaaggtttc atttccttgc tcatctacta gtgtgattag
    22381 ttcacgttct tcgtggtcgt ggttatgatc gtgtgacata gcctctcctt tatattaaaa
    22441 ttttctatct aaataatttt gtaaaatcag ctgagctgct aacttatcaa tgactttctt
    22501 gcgcttattg cgactgatat ctgcttgttc aatcaacatg cgctcagcag ccactgttgt
    22561 caagcgttca tcctgatagt ctaatggtaa accaaaaaac tcttctagct ttgctccgta
    22621 ggcttgacta gcttctacgc gcggtccact tgtattgttc atgtttttag gcaagcccac
    22681 tacaaatcgt tccaccttgt aagtatcaac caattcctta acgcggtcaa aaccaaattg
    22741 gccttgttct tcatttatct ggatgatttc aagcccttga gctgtaaaac caagcggatc
    22801 gctaatcgcc acccctaccg tttttgaacc gacgtccaat cccataattc tcataggtta
    22861 tagatcgact ccttgtcctt tgaggtagta gcgaaccaat tcctcaacga tttcatcacg
    22921 ctcatactta cggatttgat ttcgtgcatt attataacga ggaacgtagg cagggtctcc
    22981 actcaatacg taacctacga tttggttaat tgggttgtaa cccttatcgt tcaacgaagc
    23041 ataaacatct gtcaaagttt cgctaatttc ttttttattg gaatcgtcca atttaaaacg
    23101 tactgtttct tcagtaaatc ccattctaac accctctttc cttagaatag taccattata
    23161 gcataattcc ttaccttcta caattcaggc agtctattta tttggatttt ctattgttct
    23221 gtcgcgccat ttgccaatct atctgaaata tatttgcttg gttcattttt caaaagattt
    23281 tccaaaccaa tattcttcag atgttccaac tgggaagcct tcttgacatc cagaacttga
    23341 aaatcaaaac tagtcgttgt ttgaagttcc gttgcgctca atagttttgt ttcaagtttg
    23401 aaacctgcca atttacgagc ttcaatgata gacttatcct tctcctccgc ttcaagaaga
    23461 gctttttgag tttcctccac tccatgttgg tcaatataag tcttcaactc atcagagact
    23521 ggacgttttt gttggatagt tagactcaaa aaagtcttgt ccttgtatgt aatggtttgt
    23581 gtctgctggc taccatcatc tgacttgggc aagaccaaag tcttagttac aactgtattc
    23641 ttctcagcat tttcaataac tggcaatgcc gactgaagcg tatctttttc tgtttttgta
    23701 gctggtccag tttctttttt ctgtccgcaa ccaaccagga caaaaaggaa agctagacta
    23761 acaagaacta tttttttcat ttctttcttc tttctttttg aaattaaaat agaataagac
    23821 tgggaagtgc tcccagcctt gatgtttata gagctgcacg caaacgtgct tctgcatttt
    23881 ctacattacg gacagagcgt ggtaggaagg cacgaatatc gtcttccttg tagccaactt
    23941 gcaggcgttt ttcatctaca aggattgggc tctttaaaat tctcggtgtt tccataatca
    24001 gattgagaac ttcattgaca ctcaaatctt caatatccac tccaagggct ttggcatagc
    24061 gatttttaga cgaaacgatg ctggctattc cgttatctgt tttggttaga atatccagta
    24121 attcttctct cgtaattcct tctttaccaa ggttttgttc tttataactt aactggtggg
    24181 cattgagcca ggtttttgct tttttacagc tagtacaact tgagactgta taaattttaa
    24241 tcatgtacct acccctttcg ctacatgtta ctatcagttt agtctattat accataaaaa
    24301 acatccgact tgcgacctat ttttaat
//
LOCUS       DAVBIC010000033        24180 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.033, whole genome shotgun sequence.
ACCESSION   DAVBIC010000033 DAVBIC010000000
VERSION     DAVBIC010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24180)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24180)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24180
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.033"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            <1..263
                     /locus_tag="VQ664_001325"
     CDS             <1..263
                     /locus_tag="VQ664_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2789484.1"
                     /translation="WFQKFLLPTLTTPSAIIMDNARFHRMGKLELLCEEFGHKLLPLP
                     PYSPEYNPIEKTWAHIKKHLKKVLPSCCNTFYEALLSCSCFN"
     gene            complement(470..2728)
                     /locus_tag="VQ664_001326"
     CDS             complement(470..2728)
                     /locus_tag="VQ664_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HET2789485.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKAEVKSSEKEK"
     gene            complement(2957..3187)
                     /locus_tag="VQ664_001327"
     CDS             complement(2957..3187)
                     /locus_tag="VQ664_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HET2789486.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            3377..4060
                     /locus_tag="VQ664_001328"
     CDS             3377..4060
                     /locus_tag="VQ664_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET2789487.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSEIVRAGINAVPKGQLEAAYSLGIRPKNAMRYVILPQAVKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
     gene            4060..4794
                     /locus_tag="VQ664_001329"
     CDS             4060..4794
                     /locus_tag="VQ664_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET2789488.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKVIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVMENI
                     TLSPIKTKGESREVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDIAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLSKVL"
     gene            4948..5805
                     /locus_tag="VQ664_001330"
     CDS             4948..5805
                     /locus_tag="VQ664_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HET2789489.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKTAKLKEETALVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGYRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIDLEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLTHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASHITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            5947..6819
                     /locus_tag="VQ664_001331"
     CDS             5947..6819
                     /locus_tag="VQ664_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HET2789490.1"
                     /translation="MKVINQTLLEKVIIERSRSSHKGDYGRLLLLGGTYPYGGAIIMA
                     ALAAVKSGAGLMTVGTDRENIPALHSHLPEPMAFSLQDQQLLKEQLEKAEVILLGPGL
                     GDNAFGEDLVKQVFAGLKQNQILIVDGGALTILARTSLSFPSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASVLTSFPQGTILVEKGPATRIWEVGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFVGQFRQASLYERVAVATHLHSAIAQELSQENYVVLPTEISRYLPKIMK
                     IICQQERVSKDKLV"
     gene            7101..7784
                     /gene="rpiA"
                     /locus_tag="VQ664_001332"
     CDS             7101..7784
                     /gene="rpiA"
                     /locus_tag="VQ664_001332"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HET2789491.1"
                     /translation="MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQITAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRHFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QISTSKKGK"
     gene            7798..9009
                     /locus_tag="VQ664_001333"
     CDS             7798..9009
                     /locus_tag="VQ664_001333"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HET2789492.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAESNPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            9011..9553
                     /locus_tag="VQ664_001334"
     CDS             9011..9553
                     /locus_tag="VQ664_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HET2789493.1"
                     /translation="MTRYALLVRGINVGGKNKVVMAELRQELTNLGLEKVESYINSGN
                     IFFTSIDSKAQLVEKLETFFAVHYPFIQSFSLLSLEDFEAELENLPAWWSRDLARKDF
                     LFYTEGLDVDQVIATVESLELKDEVLYFGKLGIFWGKFSEESYSKTAYHKYLLKVPFY
                     RHITIRNAKTFDKIGQMLKK"
     gene            9569..10378
                     /locus_tag="VQ664_001335"
     CDS             9569..10378
                     /locus_tag="VQ664_001335"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HET2789494.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIGFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKLDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            10854..11834
                     /locus_tag="VQ664_001336"
                     /pseudo
     CDS             10854..11834
                     /locus_tag="VQ664_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855254.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
     gene            11859..12371
                     /locus_tag="VQ664_001337"
     CDS             11859..12371
                     /locus_tag="VQ664_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin"
                     /protein_id="HET2789495.1"
                     /translation="MSAQITINHKKARYVRIELEGYNALSLAEVEVFRFIATNAETAT
                     QVSKPVQPISQTPVKDKTLTIQHSGAYIARYSITWEEVPVDKDGNQVVRSHSWEGNGR
                     NQTAGFVLNLPIKENMRNLRVKIEKKTGLLWNRWQTIYENRPISAQPHRKITHWGTTL
                     NSKVSDDDVL"
     gene            13018..13728
                     /gene="deoD"
                     /locus_tag="VQ664_001338"
     CDS             13018..13728
                     /gene="deoD"
                     /locus_tag="VQ664_001338"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HET2789496.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLDDAVCFNEVRN
                     MFGYTGTYKGHCVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKKLGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(13751..14275)
                     /locus_tag="VQ664_001339"
     CDS             complement(13751..14275)
                     /locus_tag="VQ664_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HET2789497.1"
                     /translation="MKIAIIGYSGSGKSTIAEKLSNYYSIPKLHMDTLQFQPGWQDSD
                     CEWMLTEIKNFLTKHKAWVIDGNYSWCYYQERMQEADQIIFLNFSPLTCLFRAFKRYL
                     KYRGKVRESMAADCPERFEWEFIRWILWDGRSKTQKENYQKLCQEYSHKVTILRNQRE
                     LDQFLDKKRKSYNS"
     gene            complement(14328..14564)
                     /locus_tag="VQ664_001340"
     CDS             complement(14328..14564)
                     /locus_tag="VQ664_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HET2789498.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSAKLAK"
     gene            complement(14632..15552)
                     /locus_tag="VQ664_001341"
     CDS             complement(14632..15552)
                     /locus_tag="VQ664_001341"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HET2789499.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEKKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVESFAHQVWISINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            15742..16146
                     /locus_tag="VQ664_001342"
     CDS             15742..16146
                     /locus_tag="VQ664_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789500.1"
                     /translation="MKILKRYILELCFILSFALPFIKGTNADNGRCFVETYYGFTFLM
                     EHAIVTAVFIYSFLIAFLLKKRWAKWIAAGSYCFLVLWIATEGYFFRMSLEDLIRLWT
                     SLEILTQTYQLGFYLNILLGILLIIKYFKVKQ"
     gene            16362..16943
                     /locus_tag="VQ664_001343"
     CDS             16362..16943
                     /locus_tag="VQ664_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET2789501.1"
                     /translation="MYYAENPDAAHDIHELRVDLLGQKMTFLTDAGVFSKKMVDFGSQ
                     LLLKCLDVNQGETVLDVGCGYGPLGLSLVKVYGVQATMVDINTRALDLARRNAEKNNA
                     KATIFQSNIYEQVEGHFDHVISNPPIRAGKQVVHEIIEKSKDFLETGGDLTIVIQKKQ
                     GAPSAKSKMEDVFGNCEILKKDKGYYILRSVKE"
     gene            16940..18217
                     /locus_tag="VQ664_001344"
     CDS             16940..18217
                     /locus_tag="VQ664_001344"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HET2789502.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLVEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIRGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVHQHLENGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDALDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            18235..18897
                     /gene="deoC"
                     /locus_tag="VQ664_001345"
     CDS             18235..18897
                     /gene="deoC"
                     /locus_tag="VQ664_001345"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HET2789503.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYDFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSAVKAFETKEAIQNGADEIDMVINVGALKSGNL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKIVVCQLAQKAGADFVKTSTGFSTGG
                     ATIADVTLMRETVGSDMGVKAAGGARSYADALAFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            18884..19273
                     /locus_tag="VQ664_001346"
     CDS             18884..19273
                     /locus_tag="VQ664_001346"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HET2789504.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGSVYTGVNIE
                     NASYPLTNCGERTAIFKAISEGQREFSELIVYGQTEKPISPCGACRQVMAEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            19363..20415
                     /locus_tag="VQ664_001347"
     CDS             19363..20415
                     /locus_tag="VQ664_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HET2789505.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQAWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALNNAVKDAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDISNKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            20559..22094
                     /locus_tag="VQ664_001348"
     CDS             20559..22094
                     /locus_tag="VQ664_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2789506.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEIAGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQELGVLMAGGNLGKEK
                     SDV"
     gene            22087..23145
                     /locus_tag="VQ664_001349"
     CDS             22087..23145
                     /locus_tag="VQ664_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2789507.1"
                     /translation="MSKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLAELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            23148..24104
                     /locus_tag="VQ664_001350"
     CDS             23148..24104
                     /locus_tag="VQ664_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2789508.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGIIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
BASE COUNT         7026 a         4376 c         5495 g         7283 t
ORIGIN      
        1 catggtttca gaagtttctc ttaccaacat taaccacacc atcggctatt attatggata
       61 atgcaagatt ccatagaatg gggaagctag aacttttatg cgaagagttt gggcataaac
      121 ttttacctct tcctccctac tcacctgagt acaatcctat tgagaaaaca tgggctcata
      181 tcaaaaagca cctcaaaaag gtattaccaa gttgttgcaa taccttttac gaggctcttt
      241 tgtcctgctc ttgtttcaat tgactatagc agattgaaat aagatgagaa caaatcgatt
      301 gggaaagtaa aattaatttc tataaatgtt ttagcaattg tttcgtacta tttcagattc
      361 agtctactat atatcataat ggacaaaggg caagctgtca agaaattaca gttattttag
      421 taaaaaaaga agcagaaaaa tttaattttc tactcctttt ctataggatt tatttttctt
      481 tttcagaact tttaacttca gcttttttgg cagatttaat ctgaatgttt cccttgctag
      541 tcataactgc tttgagatct ttttcgcttg gattttcaag gtagtagtca gtgattgtgt
      601 cctcaatata gtcttgaata gtccgacgaa gtgggcgtgc tcccattttt ggatcataac
      661 ctaggtcaac caacttttcc ttgaccttgt cagttacatc caaacgaatg ttgttgctag
      721 agaggcgctt gttaacatct gctagcatga gctcgacaat ctgaaggagg ttatccttgc
      781 tgagagcctt aaattcgata atgccatcaa aacggttcat aaactctggg ctaaagaagt
      841 taccgagttc accgaggaca gaattggtac gtccttctct agcagcacca aatccaacgc
      901 tagcttcggt ctttcctgta cctgcatttg aggtcatgat aatgatggca tccttgaagc
      961 taacggtgcg tccttgcccg tctgtcaaac gaccatcgtc caagacttga agaaacatgt
     1021 gcataacatc tgggtgagct ttttccactt catcgagaag gatgagagaa tatggattgt
     1081 ggcgaacttt ttcagttaat tgaccagcct catcatagcc aacataacct ggaggagcgc
     1141 cgaccaactt agccacacta tgtttttcca tgtattcact catatcaaag cgaatcatac
     1201 tatcagcaga accaaaaagt tcgatagcca gttgtttgga aagttctgtc ttaccgacac
     1261 cagttggccc aacgaagagg aagcttccga ttgggcggtt aggggtacca agtccgacac
     1321 gattacggcg aatagccttg gcaatcttat cgactgcatc atcttggcca ataacatgag
     1381 acttgagatc ttcggctaga tggatgagtt gagattgttc tttctctttc aaatcaccaa
     1441 cagggatatt ggttttctgc tcgataatgt gctcaatagt tttctcgctg atgataggag
     1501 tatcctggtc tgtgatcttt ttcttttgca tttccttata cttggcaatc tggtcgcgga
     1561 agtaggccgc cttctcaaaa tcttcttctc gtgtagcttg agacttgaga ttttcagcct
     1621 caatcaagcg ctgatcaatt actttaggat ccacaaaatt caaggtcaag ttcatcttag
     1681 aaccagcttc atctaggagg tcaatggcct tgtcaggcaa gaagcgatct tggatgtagc
     1741 gattggaaag agttgcagct gcttcaatcg cagcatctgt atattgaacg tggtggtaat
     1801 cttcgtattt cttttgaatc cctttgagaa tagtgattgt ttcgtccacc gttggttcat
     1861 cgactttaac aggctgcata cgacgctcga gggcagcatc cttttcaatg atacggtatt
     1921 cattgagggt agtagcaccg actagttgca gttctccacg agcaagggct ggcttgagga
     1981 tatttcctgc gtccatatta ccatcactcg cagaaccagc accaacaatt tcatggattt
     2041 catcgataaa gaggatgatg tcttcacgtt tgcgaatttc ttccatgagt ttttgcatgc
     2101 gttcttcaaa ttgtcctcga atccccgttc cttgaactaa gctaaccaca tccagacgga
     2161 tgacttgttt accttggagt ttatgtggca catcgccatc gacaattttc tgagctagac
     2221 cttcgacaac ggccgttttt ccgacaccag gttcaccgat aaggacagga ttattcttgg
     2281 ttctacgatt gagaatctcg atgacacgga taatctcatc gtcgcgccca ataacggggt
     2341 caatgtctcc acgacgggca atttcagtta cattaatacc aaattcttcc agcaggcctt
     2401 tttcttggct aggtggcgga gtttgagcag atccacgatt ttgggaacca taaccgccgt
     2461 ttccaccgta acctccacct gattgggttg ggggaatagg aggagtattg ctagaaggtc
     2521 tgaaattgtt tagatcattg aagaaatcac caaagggatc gaagtcacga ttgttcagat
     2581 ccgtcatacc tttgaagagg ctattgttag gatctgtttt gataatctta tagcagtttt
     2641 gacagaggtc aatttgtttt tgttttccat tgagattggt gtaaagatga attgttgagt
     2701 cgttaatttt acagttttga caaagcatac atctacctca tttctttctt tagcctgact
     2761 tgtttaaagg tcaaaaatag tcaaattcta tactctcatt ataacaggat tggggtgtaa
     2821 agcaagtaaa aagattgaag ctttgagaag ttgttacaat gaaaattttt gtgaatttgg
     2881 actataaaaa aatcctattt gtgagacaaa aaggatttta cttagacatg cagggacaat
     2941 cccagcttgt tttagattag tagagaagtt cgtaaatttc cattgcgatt aagtcaatgc
     3001 tatcaaacgt atacgtttcg cgatcttcta cgtcacgaag ggtaaagatt gggccgtttt
     3061 cttcgtcgtg gctgtacgca acttctgcaa caacaactcc ttcgcgttca aaattacgtt
     3121 ttaaatttcc gccatcgttt gccattgctt caaggcggtt gatgattcta accaaatgtg
     3181 attccatttt gattctcctt catttcttat cgttactatt ttaccataaa ggaggccaac
     3241 ttgactagaa aaaactaaga tttctcgcta attctgctag tttaaagatt tttaaataaa
     3301 ttggataaaa aatttaaatt ttaattcaaa acatgttata atcatacagt attctatttt
     3361 agaaagcagt gtgactatga atttttcttt tttacctaag tatttacctt attttaacta
     3421 tggggctgtt gtgacgattc ttatttctat ctgtgttatc tttttgggaa ctattttggg
     3481 tgttgtcttg gcttttgggc aacgttcaaa gtttaaaccg cttgtttggt tggccaactt
     3541 gtacgtttgg attttccgtg ggacaccgat gatggttcaa attatgattg cctttgctct
     3601 tatgcatatc aatgctccga ctattcagat tggaatttta ggtgttgatt tttcgcgtct
     3661 gattccaggg attttgatta tctctatgaa tagtggtgct tatgtttcgg agattgttcg
     3721 tgccggaatc aatgcggttc caaaaggtca gctagaggcg gcttattcgc tagggattcg
     3781 tcctaaaaat gcgatgcgtt atgtgatttt gccacaagca gtcaaaaata tcttgccagc
     3841 attggggaac gaatttatca ccattatcaa ggacagctcc ctcttatcag ctattggggt
     3901 catggagttg tggaatgggg ctacaacagt ttctacaaca acctatctac ctttaacacc
     3961 acttttattt gcagcatttt actacttgat tatgacctct attctgacag tagccttgaa
     4021 agcttttgaa aaacatatgg gacaaggaga taagaaataa tgacagaaac cttgataaaa
     4081 attgaaaatt tacataaatc ttttggaaag aatgaagtat tgaagggcat caacctcgag
     4141 attaaaagag gagaagttgt cgttatcatc ggtccttcag ggagtgggaa atctaccttg
     4201 cttcgctcta tgaatttgtt ggaggaagca accaagggga aggttatctt tgagggagtc
     4261 gatattacgg acaagaagaa tgacctgttt gccatgcgtg agaagatggg catggttttc
     4321 caacaattta acctctttcc taatatgact gtgatggaaa atattacctt gtcacctatc
     4381 aagactaaag gtgaaagcag ggaagttgct gagaagagag cccaagagct tttggaaaaa
     4441 gttggtttgc cagataaggc agacgcttat ccacagagtc tgtcgggtgg gcaacaacaa
     4501 cggattgcca tcgcgcgtgg gttggctatg gaaccagatg ttttgctctt tgacgaacca
     4561 acttcagcct tggatcctga aatggtaggt gaggtattgg ctgttatgca agacattgcc
     4621 aagtcaggga tgactatggt tatcgtaaca catgagatgg gatttgcccg tgaggtggca
     4681 gatcgtgtta tctttatggc agacggtgtg gttgttgaag atgggacacc tgagcagatt
     4741 tttgaacaaa cccaagaaca acggactaaa gatttcttga gtaaggtttt ataatctatt
     4801 ttaaaatttc aagacaagat tagtgaaaag ttcaaccaga gctttttctt atagtttgaa
     4861 actataggat aacctaggaa agaagtgtta gagggcacta gcagtttttg gtataatgga
     4921 agatatttga aagaaaagag aagtgatatg acacagatta ttgatgggaa agctttagcg
     4981 gccaaattgc aggggcagtt ggctgaaaag actgcaaaat taaaggagga aacagctcta
     5041 gtgcctggtt tggtagtgat tttggttggg gataatccag ccagccaagt ctacgttcgc
     5101 aacaaggaga ggtcagctct tgcggctggt taccgtagcg aagtagtgcg agttccagag
     5161 accattactc aagaggaatt gttagacctg attgctaaat ataatcagga tccagcttgg
     5221 catgggattt tggtccagtt gccattacca aaacatatcg atgaagaggc ggttttatta
     5281 gccattgacc cagaaaagga tgtggatggt ttccatcccc taaacatggg acgtctttgg
     5341 tctggacatc cagtcatgat tccctcgaca cctgcaggaa ttatggaaat gtttcatgaa
     5401 tatgggattg acttggaagg taaaaatgcg gtcgtaatcg gtcgttcaaa tatcgttgga
     5461 aaacctatgg ctcagcttct tttggctaaa aatgcgacag taaccttgac ccactcacga
     5521 actcataatc ttgccaaggt ggctgctaaa gcagatattc ttgtagtcgc aatcggccgc
     5581 gccaagtttg tgactgctga ctttgtcaaa ccaggtgcgg ttgtcattga cgttgggatg
     5641 aatcgagatg aaaatgggaa gctctgtgga gatgttgatt atgaggcagt tgcaccactt
     5701 gctagccata tcacgccagt ccctggaggt gtcggtccta tgaccattac catgctgatg
     5761 gagcaaactt atcaagcagc acttcggaca ttggatagaa aataagagaa gcattcgatt
     5821 aatagagtgt attttctata gctatatcta aaatggcaga aatgaatatt aaattttaga
     5881 tataagatta caaaaggagg tctgcgtctc ctttttattg tataataaaa gtgagaggaa
     5941 aaaaggatga aagtgattaa tcaaacctta ttagaaaaag ttattattga acgttctcgt
     6001 tcaagtcata aaggagatta tggtcgtctg ctgctgcttg gtggtactta tccttatgga
     6061 ggtgccatca tcatggctgc tttagcagct gtaaaaagcg gtgcaggatt gatgaccgtt
     6121 ggaacggaca gggaaaatat cccggctctg cacagccatt tacctgagcc tatggccttt
     6181 tctcttcaag accagcaatt gttaaaagag caattggaga aggcagaagt tatcttgctg
     6241 gggcctggtt taggagacaa tgcttttgga gaagatttag ttaaacaggt ctttgctggc
     6301 ttaaaacaga atcagatttt gattgtagac ggaggtgcct tgaccattct tgctaggaca
     6361 agtttgtcat ttccctcaag ccagcttatc ctaactcctc accaaaaaga atgggaaaaa
     6421 ttatctggaa ttacgattga aaagcaaaag gaagatgcaa cggctagtgt tctgacttcc
     6481 ttccctcaag gaacaatttt ggtggagaaa ggcccagcta ctcgtatttg ggaagttggc
     6541 caatctgatt attaccagtt acaggttggt ggtccttatc aggcgactgg gggaatggga
     6601 gatactctgg ctgggatgat cgcaggattt gtaggccaat tccgacaggc cagtctctac
     6661 gagcgtgtgg cagtagcgac ccatcttcat tcagccatag cccaagaact atctcaagaa
     6721 aattatgtgg tcttaccgac ggaaatcagc aggtatcttc ccaaaataat gaaaattatt
     6781 tgtcaacaag agagggtaag caaagataaa cttgtttaaa atagacagat aaatctactt
     6841 ccttctctta atttatgatt cttgaaatgc gcctgcttta aggctaaact agacgtatca
     6901 aagttaagag tttgtttttg taactggaaa gagatgaaca aatcaaatac ataaaagata
     6961 aactcatttt tattcgtttt gtaaaaataa aatgcatatt tttaaagaaa gattgatgaa
     7021 aaatgtagat ttgatgtttt tacttgaata aaaagcggtt tcatagtaaa ataagaactg
     7081 agaatgatgg aggtaaatcg gtggaaaatc tgaagaaaat ggcaggtatc aaggctgctg
     7141 agttcgtgag cgatggaatg gtcgttggac ttggaacagg ctcgactgcc tattattttg
     7201 tcgaagaaat cggtcgtcgt atcaaggaag aaggattgca gattacagct gtaacaactt
     7261 ctagtgtgac cactaaacag gcagaaggcc ttaatatccc gctcaagtct attgaccaag
     7321 tagactttgt cgatgtgacg gttgatggcg cggatgaagt ggatagtcag tttaatggaa
     7381 tcaaaggcgg tggtggtgcc cttctcatgg aaaaggtggt cgcaacacca tcaaaagaat
     7441 acatttgggt ggtggatgaa agcaagctgg tcgaaaaact aggtgctttt aaattgccag
     7501 tagaagtggt tcagtatggt gcagagcagg tctttcgtca ttttgaacga gctggctaca
     7561 aaccaagttt ccgtgaaaaa gacggtcaac gttttgtgac ggatatgcag aattttatca
     7621 ttgacctcgc cttggatgtc attgaaaatc caattgcttt tggacaagaa ttggaccatg
     7681 tcgttggtgt tgtggagcat ggtttattca accaaatggt ggataaggta atcgttgctg
     7741 gacgagatgg agttcagatt tcaacttcaa aaaaaggaaa atagaagggg gcataagatg
     7801 tctaaattta atcgtattca tttggtggta ctggattctg taggaatcgg tgcagcacca
     7861 gatgctaata actttgtcaa tgcaggggtt ccagatggag cttctgacac actgggacac
     7921 atttcaaaaa cagttggttt gaatgtccca aacatggcta aaataggtct tggaaatatt
     7981 cctcgtgaaa ctcctcttaa gactgtagca gctgaaagca atccaactgg atatgcaaca
     8041 aaattagagg aagtatctct tggtaaggat actatgactg gacactggga aatcatggga
     8101 ctcaacatta ctgagccttt cgatactttc tggaacggat tcccagaaga aatcctgaca
     8161 aaaatcgaag aattctcagg acgcaaggtt attcgtgaag ccaacaaacc ttattcagga
     8221 acggctgtta tcgatgattt tggaccacgt cagatggaaa ctggagagtt gattatctat
     8281 acttcagctg accctgtttt gcagattgct gcccacgaag acattattcc tttggatgaa
     8341 ttgtaccgta tctgtgaata cgctcgttcg attacccttg agcgtcctgc ccttcttggt
     8401 cgcatcattg ctcgccctta tgtaggtgaa ccaggtaact tcactcgtac ggcaaaccgt
     8461 cgtgacttgg ctgtatctcc attttcccca actgttttgg ataaattgaa tgaggctggt
     8521 atcgatactt atgctgtggg taaaatcaac gatatcttta acggtgctgg tatcaaccat
     8581 gacatgggtc acaacaagtc aaatagtcat ggaattgata cactattgaa gactatggga
     8641 cttgctgagt ttgaaaaagg attctcattc acaaacctag ttgactttga tgccctttac
     8701 ggccatcgtc gtaatgctca cggttaccgt gattgcttgc atgagtttga tgaacgctta
     8761 cctgaaatta tcgcagctat gagagagaat gaccttctct tgattactgc ggaccatgga
     8821 aatgacccaa cgtatgcagg aacggatcac actcgggaat atattccatt gttggcctat
     8881 agccctgcct ttaaaggaaa tggtctcatt ccagtaggac attttgcaga tatttcagcg
     8941 actgttgccg ataactttgg tgtggaaact gctatgattg gggaaagttt cttagataaa
     9001 ttggtataag atgacgcgct atgctttgct ggtgagaggt atcaatgttg gtggtaagaa
     9061 taaggtcgtc atggcggagc ttcgtcaaga attgacaaac ttgggactgg aaaaggttga
     9121 gagctacatc aatagtggca atattttctt tacttcgata gattccaaag cccaattggt
     9181 tgaaaagcta gagactttct ttgcagtcca ttatccattt attcagagct tttctttact
     9241 gagtctagag gactttgagg cggaacttga aaatctacca gcttggtgga gcagagactt
     9301 ggcacgaaaa gattttctct tttacactga gggtttggat gtggaccaag tcatcgcgac
     9361 agttgaaagt ttagagctga aagatgaagt gctttatttt ggaaaacttg ggattttctg
     9421 ggggaaattt tctgaagaat cctattctaa gactgcctat cataagtact tgctgaaggt
     9481 gcctttctac cgccacatta ctattcgtaa tgctaaaacc tttgacaaaa ttggtcaaat
     9541 gctaaaaaaa taataaagga gacacacaat gacattttta aacaaaatcc atgaaactgc
     9601 tactttcctg aaagaaaagg gaattgcagc ccctgagttc ggtctaatcc ttggatcagg
     9661 acttggagaa ttggcagaag aaatcgaaaa tccagttgta gtagactatg ctgagattcc
     9721 aaactggggc cgttcaacag tagtcggtca tgctggtaaa ttggtatatg gtgaactggc
     9781 aggtcgcaag gtcttggctc ttcaagggcg tttccatttc tatgaaggga atcctctgga
     9841 agtggtgact ttcccagttc gtgtgatgaa agttcttgga tgtgaaggtg ttattgtaac
     9901 caatgcagct ggcggtatcg gatttggtcc tggtaccttg atggctatct cagaccatat
     9961 caacatgacg gggcaaaatc cattgatggg tgaaaacttg gatgactttg gcccacgttt
    10021 cccagatatg tctagggcct acacaccaga ataccgtgcc actgcccatg aagtggctaa
    10081 aaaacttaat atcaagcttg atgaaggtgt ctatatcgga gttactggtc cgacttatga
    10141 aacaccagca gaaattcgtt cctataagac actgggagca gatgcagttg gtatgtctac
    10201 ggttcctgaa gttatcgtgg cagcccactc tggcttgaaa gttctgggaa tttcatgtat
    10261 cactaacttt gcggccggtt tccaagaaga actcaatcac gaagaagttg tagaagtgac
    10321 tgaacgtgtt aaaggtgatt tcaaaggctt gcttaaagcg attcttgctg aattgtaaga
    10381 aaaaagattt aaaaggggga gtgcctctgt tttttcagga ttgactgcct atccggatta
    10441 aagaagaaac agaggaatac tatgagcttc ttcctgctct tataactgaa agaagcggaa
    10501 gaataggtat gtctgatctg atagccagca ttgtgaaaga caagattcta ggatactagc
    10561 attagcttcc tagccaagca gactagtatg ataaggagag atgagaatga attgactttc
    10621 tgaatttctc agtcttatca tatatagcac aatgagattt cgcttgagtc tgcttgtaaa
    10681 taaacgaaaa gaaagataag aaataatgaa aattggtcaa cgaattatgc gctttggcat
    10741 aaaaaattaa gtatcggagt tgtatctgtt gtagtcggct ttgatttcta gctccagctg
    10801 gaatttcagc caatgaagta aagcaagatg taacatctga agtggtaata ggtgtgctag
    10861 attctaagga ggaattgaaa gagtcagaaa atgatgctcc aaaactagaa actcctctta
    10921 gagaggagcc aagactagct cctcaaacgc ttccggaagc aagtgaagtt cttgaaaaca
    10981 aaagggaaga gtcaaaagta gagataacat aaccagctca agcggatgat atccgcaagg
    11041 ttgttgggga attagccaag gatataagta ttactaagtt gtatatgaca ggtcattctc
    11101 ttggatgtta cctagctcag attgcagcgg ttgaagctta ccaaaaatat cctgattttt
    11161 ataaccatgt attgaggaaa gtgacaactt tcagtgctcc taaagtgatt acttccagaa
    11221 ctgtttggaa tgctaagaat ggtttctggg atgttggttt ggaaagtcgt aaattagctg
    11281 ttagtggaaa aattaagcat tatgtggttg ataatgacaa tgttgtgact cccttgattc
    11341 ataataatcg tgatattgtt acatttacag gtaattcacg ctttaaacac cgttctcgtg
    11401 gctattttga aagtccaatg aatgatattc ctaactttaa tattggtaaa caagctacct
    11461 tggataaaca tggttatcgt gatccgaaat tggataaagt gcgattcttt aagaaacagg
    11521 ctctgcctcg atcttctagt caaccaagcg ctgaaccaat ggaaaatatt gccttaggaa
    11581 aacaggttac tcaaagttcg acagctttcg gaggagatgc tagaagagct gtggatggca
    11641 aagtcgatgg taactatggt cacaattctg tcactcatac aaacttccaa tctaagcctt
    11701 ggtggcaagt agatttggct aaagaagaaa ccattcgcca aatcaatatt tacaaccgaa
    11761 cagacactgc ccaggataga ttggcaaact ttgatgtcat tcttttagac agttctggta
    11821 aagaaattga gtgaaaacgt ataatatctc ctaaagatgt gtcagcacaa attacgatta
    11881 accataaaaa agcgcgctat gttcggattg agctagaagg ctataatgcc ctcagtcttg
    11941 cagaagttga agttttccgc tttatagcta cgaatgctga aacggcgaca caagtttcta
    12001 agccagttca accaatcagt cagactcctg tgaaagataa aacattgaca attcaacaca
    12061 gtggagctta cattgcccgc tactccataa cttgggaaga agttccagta gataaagatg
    12121 gaaaccaagt tgttcgtagt cattcttggg aaggaaacgg tcgcaaccag actgcgggtt
    12181 ttgtcctcaa cctcccaatc aaagaaaata tgagaaatct gcgagttaag attgagaaaa
    12241 agacgggcct actatggaat agatggcaaa caatctatga aaacagacca atttcagctc
    12301 aaccccaccg taaaattacc cattggggta cgacattgaa ttccaaggtg agtgacgatg
    12361 atgtcttgta atctgatggt acaatgacag ttagtttgtc tagtttataa gaaagtacta
    12421 cctgagcttg aatagaactc aggtagctct ctgtgaaaga acaaaattaa tactcaatga
    12481 aaatcaaaga gcaaactagg aaactagccg caggttgctc aaagcactgc tttgaggttg
    12541 tagataagac tgacgaagtc agtcacatat ataatccaag gcgacgttga cgtggtttga
    12601 agagattttc gaagagtata aacagaaagg tagagcgcgt gttctaattt gaacacgagt
    12661 agaaaacttt tctaaaaaca aaaacgaaag gatgggtaaa ctgtattcgc tgaactgaat
    12721 acgggcgact ctcctctaaa tcaaaattaa gaaaggaatt gaccccaccc taaaagtagt
    12781 gggaaaaaga tagttggtct agcgagcatc gctcactgcg cccaactcct attttccctt
    12841 cgctttttga tgggtttggt atctttctca atataaaata aagaaaggta gagcgtgtgt
    12901 tttgatttga acacgagcgg aaaactcgga aaatagataa tctgactgaa aaatcaggat
    12961 ttctcgtcag gttcctaatt ttcagtcgtt ttcttctcgc tctttgtatc ataaattatg
    13021 tctatccata ttgctgctca gcagggtgaa attgctgata aaattcttct tcctggggat
    13081 cctcttcgtg ctaagtttat tgcggagaat ttccttgatg atgctgtttg ttttaacgaa
    13141 gtgcgtaaca tgtttggtta cactggtact tacaagggtc actgtgtatc tgtcatggga
    13201 actgggatgg gaatgccatc tatttcgatt tatgcgcgtg agttaatcgt agactacggt
    13261 gtgaagaaat tgattcgtgt gggaactgca ggttctttga atgaagaggt tcatgttcgt
    13321 gaattagttt tggcgcaggc ggctgcaacc aactcaaaca tcgttcgtaa tgactggcca
    13381 cagtacgatt ttccacaaat tgctagcttt gatttgcttg ataaagccta ccatatcgcc
    13441 aaaaaacttg gtatgactac tcacgttggg aacgttttgt catctgatgt cttttactca
    13501 aattactttg aaaagaatat cgagcttggt aaatggggag tcaaggctgt ggaaatggaa
    13561 gcagcagctc tttactatct tgctgcccaa taccatgttg atgcgctagc tatcatgacc
    13621 atctctgata gcttggtcaa tccagacgaa gacacaactg cagaagaacg tcaaaatacc
    13681 ttcactgata tgatgaaggt tggtttggaa accttgattg cagaataatt atagccaaaa
    13741 aggaagccct ttatgaattg taggacttcc ttttcttatc cagaaattga tctagctctc
    13801 tctgatttcg aagaatagtg actttatgtg aatattcttg gcaaagtttt tggtaatttt
    13861 ctttttgagt tttgctacgc ccatcccaaa gaatccatct gataaactcc cactcaaagc
    13921 gttcagggca atctgccgcc atactttctc tgacttttcc acggtattta agataacgct
    13981 taaaggctct aaagagacag gtcaatggcg aaaaattgag aaagatgatt tggtcagctt
    14041 cttgcattcg ttcttggtag tagcaccaag aataattacc atcgatgacc caagctttat
    14101 gcttggtgag aaagtttttt atctcggtta acatccattc gcagtcactg tcttgccaac
    14161 caggttgaaa ttggagtgtg tccatgtgca gttttggaat ggagtagtag ttagataact
    14221 tttctgctat agttgactta ccagaaccag aatatccgat aattgcgatt ttcattttct
    14281 actttttcct atttggagac aaaaaaacag cctctatgga ctgtttctta tttagcaagt
    14341 ttagctgaaa gacgagcttt atcgcggctt gctttgtttt tgtgaatcaa acctttagtt
    14401 tctgctttat cgatagctga gctagcagca cggaaaagtt cttcagatgg gtttgcttcg
    14461 aaagctttta tagcagtacg catagctgat ttttgagctg agttcttttc gttttgttta
    14521 acgttcaatt cagcgcgttt gatagctgat ttaatgtttg ccaatgttct tacctccata
    14581 tttactaact ataccattat atatgaaaac ttacgttttg acaagggaaa attacttttt
    14641 taagtaaatt tcatcgattt catggttctt gcttttatga agaatcactt ctgcacgatt
    14701 tctggttggt tcaatataat tttgcagatt tgtgagattg atactgatcc agacctgatg
    14761 ggcaaaggac tccacttccc caatcggcat ctgagtaaaa cgataatagt agctatcagg
    14821 gtcgttttgg gctaggctca gcattttcaa gaaacggtcc agataccaac tttcaatatc
    14881 atccactcca gcatctacat agatggaaaa gtcaaagaag tcagtgatat agagacgatc
    14941 gttttgtgga ttttgaaaga cattaattcc ctcaacaatt acaaaatcag cagctttgac
    15001 actttgtttc ttttcgggta cgatgtcgta aacttcatga gaatagacag gaatatctac
    15061 atcttgtcca tttttgatgc ggtccaagaa gttgagaaga gcttccatat catagctttc
    15121 aggaaatcct ttacgattta aaatcccctg ctcaatcaag gtttgattgg gatagagaaa
    15181 accatcagtt gtaaccaact caaccgtagc atctgtaaac gtacgggaca gtaggatttg
    15241 aagtaggcga ctggttgtgg attttccaac ggcaacactc ccagaaaccc caataataaa
    15301 aggttgagat ttactttcac gttggaggaa aattcctttt gaaaaggcta aatcttcctt
    15361 agttcgcttg taaatctgaa tcagatgagc caaggggaga tagatatctg taacgtcttg
    15421 gagactgatt tggtcattaa aactcttgat agattccaat tcttcttctg tcaaaggagg
    15481 tgttgtcttt cgatgtaaag attgccaagt ctggcggctg attttttcaa aatgtaaaaa
    15541 ttcgttggtc atttgttttc ccctagatat tttgtctatc ataccataaa aagctaaaaa
    15601 aataaagcgg tttcttgaat gtggtaagtc aatggtatat agtataagtg atcaatttat
    15661 tgatgaaata ggagatagat tctactgatt tataagctta taaagggggc tttttagttc
    15721 acaacttata ggaggtgtac tatgaaaatc ttaaaacgtt acatattgga actctgtttt
    15781 attttaagtt ttgctttacc ttttataaaa ggaaccaatg cagataatgg tagatgcttt
    15841 gtggaaacct attacggttt tacttttttg atggaacatg ctattgtaac agctgtcttt
    15901 atctattcgt ttttaattgc tttcttacta aaaaaacgat gggcgaaatg gattgctgct
    15961 ggtagttatt gctttttagt cctatggatt gcgacagagg gttatttctt ccgcatgtca
    16021 ctagaagatt tgatacgact ttggacaagt ttggaaatcc tgacacaaac gtatcagttg
    16081 ggcttttatc taaacatttt gttaggaatt ttgttgataa taaagtattt taaggttaag
    16141 caatagaaat aataatctgc ctgattatag atgataaact ttttgttttt atctggactg
    16201 tgatatttat agttctaaat ggtttattat ttataagtgt tgaaagagat tgaagaaaat
    16261 ggcttcgtga cttgctttct tcggtctttt tcgttttatt atcaatttgt aaacgattta
    16321 caatttgagt caaattatgg taaaatagtg tcatgagtaa aatgtattat gcagaaaatc
    16381 ctgacgctgc tcacgacatt catgagttga gagtggactt gttgggacaa aaaatgactt
    16441 ttttgacaga tgcgggtgtt tttagcaaga aaatggttga ctttggaagt caactcttgc
    16501 tcaagtgtct ggatgtcaac caaggagaga cagtcctaga tgtaggctgt ggttatggtc
    16561 cattaggttt gtccttggtc aaggtttacg gagttcaggc gaccatggtt gatattaaca
    16621 ctcgtgcctt ggatttagct cggagaaatg ctgaaaaaaa taatgcaaaa gcgacgattt
    16681 tccagtccaa catctatgaa caagttgaag gacattttga tcatgtcatt tccaatcctc
    16741 ctatccgtgc gggcaagcaa gtcgttcatg aaatcattga gaaaagtaaa gatttcttgg
    16801 aaactggtgg ggatttgaca atcgtcatcc agaaaaaaca aggggctcca agtgctaagt
    16861 ccaagatgga ggatgtgttt ggtaattgtg aaatccttaa aaaagacaaa ggatactata
    16921 tccttagaag tgtgaaagaa tgagagcagt tgatttaata caaaaaaaac gagacggtca
    16981 agaactgact tcaagtgaaa ttgaatggct ggtagaaggc tatgtgtcag gaactgttcc
    17041 tgattatcag atgtctgcct ttgctatggc tgtttatttt aaaggaatga cgactcgtga
    17101 aatttctgat ttaacgatga atatggttaa gactgggcaa gagtttgacc tgtcagccat
    17161 tgatggtgtg aaagttgaca agcattctac tggtggtgtc ggcgataagg taaccttgat
    17221 tttagctcct cttgttgcta gcttcggtgt gcctgtagca aaaatgagtg gtcgtggtct
    17281 tggccataca ggcggaacaa ttgataaatt ggagtccatt aggggctatc aagtagaacg
    17341 tagtcaagag gattttattc gtcaggttca ggatattgga gtatctgtca ttgggcaatc
    17401 agaccagctg gtcaaagcag ataagcttct ctatgccctt cgtgatgtga ccgcaactgt
    17461 cgacacgatt cctttgattg cgagttcggt gatgagcaag aaaattgcgg caggggcgga
    17521 tgctattttg ctagacgtga ctgtcggtga gggtgccttc atgaagacgg ttgatgaggc
    17581 gcgtgagttg gctcaaacta tggtagatct tggtaaggtt gttggacgga agacagtagc
    17641 agtgattacg gatatgagcc agcctttggg acgagcgatt ggaaatcgtc tggaaatact
    17701 tgaagcattg gagattttgc aaggtcaagg acgtcaggat attacccact ttatttgtga
    17761 attggctcaa attatgcttg gtttggcaaa tgttaacaag actgttgaag aagttcacca
    17821 acatcttgag aatggtcaag cactggctaa gtttgaggaa atggtgcaag cccaaggtgg
    17881 agacttggaa gacctctatc gtcctgtaaa tgtagctcat gtggtggaaa tccctgctca
    17941 ggaaacgggt gtcatttcag ctcttccagc tatggacttt ggtctttatg ccatgaggct
    18001 gggggctggt cgtgcagtta agtctgatgc cttggactat gaaacaggaa ttgtttttga
    18061 aaagaagatt ggagactccg ttcaaaaggg tgaaattgtt gcaaaagtat acacaaatga
    18121 aaaaattcca cctcaactag ttacagattt ccaaaaatgt gttaaaataa gtgatgaagt
    18181 gaaaaaaatc cgtgaaattg tagaaatcat ctcctaaatg gagggaaaac cgaaatgaaa
    18241 ttaaataaat atatagatca tacgctttta aaacaagatg caaagaaaaa acaaattgat
    18301 agtttgttgt ctgaggctag agagtatgac tttgccagtg tttgcgttaa tccgacctgg
    18361 gttgaacatg ctaaaaaagg acttgaaggc acagatgtta aggtttgcac ggtagtaggt
    18421 ttccctttgg gagcaacaac ttcagccgtg aaagcatttg agacaaaaga agctatccaa
    18481 aatggtgcag atgagattga tatggtgatc aatgttggag ctctcaaatc aggtaattta
    18541 gccttggttg agtcagatat tcgcgcagta gtggaagcaa gtggtgataa gttagtgaaa
    18601 gtcattattg aagcttgcct tctgacagac caagaaaaaa ttgttgtttg ccaattggcc
    18661 caaaaagctg gggctgactt tgttaaaaca tctactggtt tttcaactgg tggtgctacg
    18721 atagcagatg ttacattaat gcgtgaaaca gttggatctg atatgggagt caaggctgct
    18781 ggtggagctc gttcttatgc agatgctctt gcctttgtcg aagcaggtgc gacccgtatc
    18841 ggaacgtcag ctggggtagc tattttaaaa ggagaattgg cagatggcga ctactgagtt
    18901 gattgaactg gcaattgaaa ccagcaaaca tgcctatgtc ccctattctc actttcctat
    18961 cggagcagtt ttagtagcca aagacggaag tgtttacacg ggagtgaata tcgaaaatgc
    19021 tagctatcct ttgaccaatt gcggtgagag aacagctatt tttaaggcta tatctgaagg
    19081 ccaaagagaa ttttcagaat tgattgtcta tggtcaaact gaaaaaccga tctcgccatg
    19141 tggtgcttgt cgccaagtga tggctgaatt ttttgaacaa gatctaaaag tgaccttagt
    19201 cgcaaaagat aaatcgacgg tcgagatgac ggtcggggaa ttacttccat actcttttac
    19261 agacttaaac tagtctgagt cgctctctga gtggcacggt ccttgtggcc aaccaatcca
    19321 tacttgcaac atcgttgcac atcttattta ggaggttcag taatgaacaa gaaacaatgg
    19381 ctaggtcttg gcctagttgc agtggcagca gttggacttg ctgcatgtgg taaccgctct
    19441 tctcgtaacg cagcttcatc ttctgatgtg aagacaaaag cagcaatcgt cactgatact
    19501 ggtggtgttg atgacaaatc attcaaccaa tcagcttggg aaggtttgca ggcttggggt
    19561 aaagaacaca atctttcaaa agataacggt ttcacttact tccaatcaac aagtgaagct
    19621 gactacgcta acaacttgca acaagcggct ggaagttaca acctaatctt cggtgttggt
    19681 tttgccctta ataatgcagt taaagatgca gcaaaagaac acactgactt gaactatgtc
    19741 ttgattgatg atgtgattaa agaccaaaag aatgttgcga gcgtaacttt cgctgataat
    19801 gagtcaggtt accttgcagg tgtggctgca gcaaaaacaa ctaagacaaa acaagttggt
    19861 tttgtaggtg gtatcgaatc tgaagttatc tctcgttttg aagcaggatt caaggctggt
    19921 gttgcgtcag tagacccatc tatcaaagtc caagttgact acgctggttc atttggtgat
    19981 gcggctaaag gtaaaacaat tgcagccgca caatacgcag ccggtgcaga tattgtttac
    20041 caagtagctg gtggtacagg tgcaggtgtc tttgcagagg caaaatctct caacgaaagc
    20101 cgtcctgaaa atgaaaaagt ttgggttatc ggtgttgatc gtgaccaaga agcagaaggt
    20161 aaatacactt ctaaagatgg caaagaatca aactttgttc ttgtatctac tttgaaacaa
    20221 gttggtacaa ctgtaaaaga tatttctaac aaggcagaaa aaggagaatt ccctggcggt
    20281 caagtgatcg tttactcatt gaaggataaa ggggttgact tggcagtaac aaacctttca
    20341 gaagaaggta aaaaagctgt cgaagatgca aaagctaaaa tccttgatgg aagcgtaaaa
    20401 gttcctgaaa aataatggat ggaagtcatt tcttaggaag cggccaaggg ccgctttttt
    20461 aagagttgag acaaagtcat tttgtctcag taaagcttgc tactagacaa actagcaagt
    20521 tttattgaaa taaaataaga ctctgaaagg aagagcacat ggcacacgaa aatgtcattg
    20581 agatgcgtga tattaccaag gtgtttggtg gatttgttgc caacgacaaa atcaacttgc
    20641 acctacgaaa aggtgaaatt catgcacttt taggagaaaa tggggctggt aagtccacgc
    20701 taatgaacat gttagcaggc cttcttgaac caactagtgg tgaaatcgcg gtcaacggtc
    20761 aagttgtcaa tctcgactcc ccatctaaag cagctagctt gggaatcggg atggttcacc
    20821 agcactttat gttggttgaa gccttcacag tggctgaaaa catcatttta ggtagtgaat
    20881 tgactaaaaa tggtgtgcta gatatcgctg gagctagcaa agaaatcaag gctctttctg
    20941 aacgttatgg cttagctgtt gacccttctg ccaaggtagc agatatctca gttggagccc
    21001 aacaacgtgt agaaatttta aaaacacttt atcggggggc tgatatcctt atctttgacg
    21061 aaccaacggc tgttttgact ccatcagaaa ttgatgagtt gatggctatt atgaaaaatc
    21121 ttgtcaaaga aggaaaatca attatcttga ttacccacaa attggatgaa attcgcgcag
    21181 tttctgaccg tgttacagtt atccgtcgtg ggaaatcaat tgaaaccgtt gaaattgcag
    21241 gggctaccaa tgctgatttg gcggaaatga tggtaggacg ttctgtttcc tttaaaacag
    21301 agaagcaagc ctctaaacca aaagaagtgg ttttgtctat caaagatttg gtggtcaatg
    21361 aaaaccgtgg tgttccagct gttaaaaatc tgtccttgga tgttcgtgct ggagagattg
    21421 ttggtattgc ggggattgat ggaaatggtc agtctgaact gattcaagcc attacaggtc
    21481 ttcgtaaggt tgaatctggt agcattgagc taaaaggaga ttcaattgta ggcttgcacc
    21541 cacgtcagat tacagaacta agtgttgggc acgttccaga agaccgtcac cgtgatggct
    21601 tgattttgga aatgatgata tctgaaaata ttgcccttca aacctactat aaagaaccac
    21661 atagtaaaaa tggaattttg aattattcaa atattacttc ttatgctaaa aagctgatgg
    21721 aagagtttga tgttcgcgct gccagtgaat tagttcctgc agctgcactc tcaggaggaa
    21781 atcaacaaaa agcaattatt gctcgtgaaa ttgatcgaga tcctgatctc cttatcgtta
    21841 gccagccaac tcgtgggttg gatgtcggtg ccattgagta tatccacaaa cgcttgattg
    21901 aagagcgtga taatggcaag gctgtccttg ttgtcagctt tgaattggat gagattttaa
    21961 acgtctcaga ccgtattgcc gttatccacg atggtaagat tcaaggtatt gtatcaccag
    22021 aaacaaccaa taaacaagaa cttggtgtct tgatggctgg tggaaacttg ggaaaggaga
    22081 agagtgatgt ctaaaaaatt acaacaaatt tcggttccct tgatttctgt atttctagga
    22141 attttactcg gagccattgt catgtggatc ttcggttatg atgctatttg gggctacgaa
    22201 gaattgttct atacagcctt tggcagtctg cgtgggattg gagaaatctt ccgtgctatg
    22261 ggtcctctgg tcttgattgg tcttggtttt gcggttgcca gtcgagctgg tttctttaac
    22321 gtcggacttc ctggtcaggc tttggcaggt tggattctca gtggttggtt tgcgctgtcg
    22381 catccagata tgccccgtcc cttgatgatt ctagcaacca tcgtgattgc cttgattgct
    22441 ggtgggattg tcggagcgat tccaggtatt cttagggcct atctagggac gtcagaggtt
    22501 attgtaacca tcatgatgaa ctacattgtc ttgtatgtag ggaatgcctt tatccatgct
    22561 ttccctaaag acttcatgca aagtacagat tcgaccattc gtgttggggc taatgcaacc
    22621 tatcagacac cttggttggc tgagttgact ggtaactcac ggatgaatat tggtattttc
    22681 tttgccatca ttgccgttgc agttatttgg ttcatgctca agaaaacaac tcttggtttt
    22741 gaaatccgtg cagttggtct taatccacat gcttcagaat atgctggtat ttctgccaag
    22801 cggactatta tcctatctat gattatttca ggtgccttgg caggtcttgg tggagctgtt
    22861 gaaggtttgg gaaccttcca gaacgtctat gttcaaggtt cgtcattagc tatcggattt
    22921 aacggaatgg cggttagttt gcttgcggcc aactcaccaa ttggtatact ctttgcagcc
    22981 ttcctatttg gcgttctcca agttggggct cctggtatga atgcggcgca ggtaccatct
    23041 gagcttgtca gcattgtaac agcgtctatt atcttctttg tcagtgttca ttaccttatc
    23101 gaacgctttg tcaaaccgaa aaaacaagtt aaaggaggta agtaaagatg tctattataa
    23161 ccttgctccc cctcttggtg tcttctatgc tgatttactc agcacctctc atctttacaa
    23221 gtatcggtgg tgttttctct gaacgtggtg gtgtggtaaa cgttggcctt gaaggaatta
    23281 tggttatggg tgccttttct ggagttgtct ttaaccttga atttgcagaa caatttggag
    23341 cagcaactcc atggctatcc ttgcttgtag caggattggt tggtagtgtt ttctctatca
    23401 tccacgcagc agcgacggtt catttccgtg cagaccatgt tgtcagcggt acggtattga
    23461 acttgatggc gcctgccttg gctgttttct tagttaaagt tctttataac aaaggacaaa
    23521 ccgacaacct aagtcaaact tttggacgct ttgatttccc agtcttggca aatatcccag
    23581 tgattggtga tatcttcttc aagtcaacta gtctacttgg ttatctggcg attgccttct
    23641 cattccttgc ttggtttatt ctctttaaga ctcaatttgg tcttcgtctc cgctctgtcg
    23701 gtgaacatcc tcaagcagcg gataccttgg gaatcaacgt ctacaagatg agatatttag
    23761 ggattattat ttcaggtttt ctaggtggaa ttggcggagc gatttatgcg caatcaatct
    23821 cagttaactt ctcagtgaca actattgttg gacctggatt tatcgccctt gctgcgatga
    23881 tctttgggaa atggaatcca atcggtgcta tgctttctag tctcttcttt ggactttcac
    23941 aaagtttggc tgttatcggt tctcaattgc cgttcctaca aggagtgcca gcggtttatc
    24001 ttcaaattgc accttatgtt ttgacaattc ttgtcttagc agccttcttt ggaaaagcag
    24061 tcgcaccaaa agcagatggt atcaactaca tcaaatcaaa ataagcatac aaaaaaacgt
    24121 cagtccaatg actgaactgc cccccaaaag ttagacagaa aaaatctaac ttttggggtg
//
LOCUS       DAVBIC010000034        23644 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.034, whole genome shotgun sequence.
ACCESSION   DAVBIC010000034 DAVBIC010000000
VERSION     DAVBIC010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23644)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23644)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23644
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.034"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            complement(70..481)
                     /locus_tag="VQ664_001351"
                     /pseudo
     CDS             complement(70..481)
                     /locus_tag="VQ664_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007897432.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(557..958)
                     /locus_tag="VQ664_001352"
     CDS             complement(557..958)
                     /locus_tag="VQ664_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001826718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2789509.1"
                     /translation="MDSASIIAHTIHQKFNLKVPNYRQEEDWARMGLPITRKEIANWH
                     IKASQYYLESLYNLLREKLLEQPLLHADETSYRVLESDSQLTYYWTFLSGKSEKQGIT
                     LYHHDQCRSGSVVQEFLGDYSGYVHCDMLRQ"
     gene            complement(966..1271)
                     /locus_tag="VQ664_001353"
     CDS             complement(966..1271)
                     /locus_tag="VQ664_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase zinc-finger binding
                     domain-containing protein"
                     /protein_id="HET2789510.1"
                     /translation="MFPVETEEITYKRKKSKGKRQALLAQFDSEEVHHQVEESICSDC
                     QGDLKEIGATLQRQELVFIPAQLKRIDHIQHAYKCQACSDKNPSDKIVKAPIPKAPL"
     gene            complement(1258..1452)
                     /locus_tag="VQ664_001354"
     CDS             complement(1258..1452)
                     /locus_tag="VQ664_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2789511.1"
                     /translation="MKIIQQQSATIDSLTNALALLREQVAYLTQKLYGKSSEKSVCPS
                     GQLNLFEEESPSEKDGDVPS"
     gene            complement(1528..1868)
                     /gene="tnpB"
                     /locus_tag="VQ664_001355"
                     /pseudo
     CDS             complement(1528..1868)
                     /gene="tnpB"
                     /locus_tag="VQ664_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
     gene            complement(1849..2034)
                     /locus_tag="VQ664_001356"
     CDS             complement(1849..2034)
                     /locus_tag="VQ664_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789512.1"
                     /translation="MPQPIVPVEIPQSRPFDSKKRNDILLKIRIGKLEVSFFQSLNLE
                     MVEQLLDKVLLYDNSSI"
     gene            complement(2338..3900)
                     /gene="guaA"
                     /locus_tag="VQ664_001357"
     CDS             complement(2338..3900)
                     /gene="guaA"
                     /locus_tag="VQ664_001357"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HET2789513.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            4042..4740
                     /locus_tag="VQ664_001358"
     CDS             4042..4740
                     /locus_tag="VQ664_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET2789514.1"
                     /translation="MLPAYMKIHDQIKKDIDEHRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERRVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKHGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQVSYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(4783..5679)
                     /locus_tag="VQ664_001359"
     CDS             complement(4783..5679)
                     /locus_tag="VQ664_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HET2789515.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMLLAYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSALTYALYIILPIALIKKWGSSLLIGVGMVIAGLVALPFTGVLQADIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAIFFAFLIMNEQFYPIDF
                     LGMAMILFAVTLISLKDLFLEK"
     gene            complement(5688..6623)
                     /locus_tag="VQ664_001360"
     CDS             complement(5688..6623)
                     /locus_tag="VQ664_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HET2789516.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSDPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGPVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQIFLEHYLADDFARDLNQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(6620..7345)
                     /locus_tag="VQ664_001361"
     CDS             complement(6620..7345)
                     /locus_tag="VQ664_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HET2789517.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDRASLVEVGEKPEFQTDLASISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESTEYF
                     IPKSEKFFLGKDRNNVELWFEEV"
     gene            complement(7429..8064)
                     /locus_tag="VQ664_001362"
     CDS             complement(7429..8064)
                     /locus_tag="VQ664_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-alkyl-2-acetylglycerophosphocholine esterase"
                     /protein_id="HET2789518.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKTIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEGEEYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKSLKDYLY"
     gene            complement(8066..8893)
                     /locus_tag="VQ664_001363"
     CDS             complement(8066..8893)
                     /locus_tag="VQ664_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET2789519.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALAHFKGRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINALFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(8915..9251)
                     /locus_tag="VQ664_001364"
                     /pseudo
     CDS             complement(8915..9251)
                     /locus_tag="VQ664_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398793.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="poly-gamma-glutamate biosynthesis protein"
     gene            complement(9252..9968)
                     /locus_tag="VQ664_001365"
     CDS             complement(9252..9968)
                     /locus_tag="VQ664_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HET2789520.1"
                     /translation="MAHGDLLYHDGLFFSAKKEDGTYDFHENFEYVTPWLKQADLAIG
                     DFEGTINKDHYLAGYLLFNAPVEVMDAIKEAGYHVLDLAHNHILDSQIEGVISMADII
                     EKAGITPIGVYTHEPRDQAPLVIKEVNAIKVALLAYSYGFNGIEQYIFQEDYNRYLSD
                     LNEDKIKAEVERAEKEADITIIMPQMGVEYRLEPTEEQKALYHKMIDWGADIIFGGHP
                     HVVEPSKTVEKDGDKKLIIY"
     gene            10491..11102
                     /locus_tag="VQ664_001366"
     CDS             10491..11102
                     /locus_tag="VQ664_001366"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HET2789521.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRAIAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEGIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            11147..11875
                     /gene="rlmB"
                     /locus_tag="VQ664_001367"
     CDS             11147..11875
                     /gene="rlmB"
                     /locus_tag="VQ664_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HET2789522.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKSLSEMTEGAVHQGFVLRVSEFAYSELDYILAKTRQEENPLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRAVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFLNRL"
     gene            complement(11914..12825)
                     /gene="trxB"
                     /locus_tag="VQ664_001368"
     CDS             complement(11914..12825)
                     /gene="trxB"
                     /locus_tag="VQ664_001368"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HET2789523.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVKEIKGENRVESVVFENVKT
                     GQVTEQAFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTDSHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(12891..13115)
                     /locus_tag="VQ664_001369"
     CDS             complement(12891..13115)
                     /locus_tag="VQ664_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HET2789524.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTARARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(13193..13936)
                     /locus_tag="VQ664_001370"
     CDS             complement(13193..13936)
                     /locus_tag="VQ664_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET2789525.1"
                     /translation="MIKISNLSKSFSGQTVLDHLNLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMSFVAQVADKILLLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(13936..14736)
                     /locus_tag="VQ664_001371"
     CDS             complement(13936..14736)
                     /locus_tag="VQ664_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET2789526.1"
                     /translation="MNVTTILASDWYQNLMQLIPDGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(14894..15250)
                     /locus_tag="VQ664_001372"
     CDS             complement(14894..15250)
                     /locus_tag="VQ664_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HET2789527.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(15263..15775)
                     /locus_tag="VQ664_001373"
     CDS             complement(15263..15775)
                     /locus_tag="VQ664_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001170346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HET2789528.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGKPQDLSNLLLAPIGTNFEKRVWDYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDINK"
     gene            complement(15775..16269)
                     /locus_tag="VQ664_001374"
     CDS             complement(15775..16269)
                     /locus_tag="VQ664_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2789529.1"
                     /translation="MEIRLAFPNEVDAIMQVMEDAKKCLADAGSDQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            16404..16850
                     /locus_tag="VQ664_001375"
     CDS             16404..16850
                     /locus_tag="VQ664_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HET2789530.1"
                     /translation="MKTTFSYPKWAEIPNIDLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            16847..17494
                     /locus_tag="VQ664_001376"
     CDS             16847..17494
                     /locus_tag="VQ664_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HET2789531.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLAIIPAII
                     SQTTPVFWSLMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILAASALQYIAIVYYM"
     gene            complement(17515..18096)
                     /gene="pdxT"
                     /locus_tag="VQ664_001377"
     CDS             complement(17515..18096)
                     /gene="pdxT"
                     /locus_tag="VQ664_001377"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HET2789532.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVA
                     AQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS"
     gene            complement(18097..18972)
                     /gene="pdxS"
                     /locus_tag="VQ664_001378"
     CDS             complement(18097..18972)
                     /gene="pdxS"
                     /locus_tag="VQ664_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HET2789533.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            complement(19124..20503)
                     /locus_tag="VQ664_001379"
     CDS             complement(19124..20503)
                     /locus_tag="VQ664_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HET2789534.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKDKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALADGKIELFRNGAF
                     LVDKKQETSIPGVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            20798..21721
                     /locus_tag="VQ664_001380"
     CDS             20798..21721
                     /locus_tag="VQ664_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HET2789535.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGISPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            21781..22386
                     /locus_tag="VQ664_001381"
     CDS             21781..22386
                     /locus_tag="VQ664_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HET2789536.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFADKAEIELVEIKTIPV
                     FNKPADKQVPAEILEIAAKIEEADGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLTHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRSAQELLRKDAEDFDWENL"
     gene            22404..>23644
                     /locus_tag="VQ664_001382"
     CDS             22404..>23644
                     /locus_tag="VQ664_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HET2789537.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRNFKFKFELEVLEIDEVPMF
                     NQDEKWDESFQLRFLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AITGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGGHGDADATSG
                     ASDSGDAGGHGGDADATAGAS"
BASE COUNT         7019 a         5314 c         4311 g         7000 t
ORIGIN      
        1 tgagaaaata accaccctcg cttttttaaa ctgagcttag gctaaaagag tccactggac
       61 tcttttactc cgtcccataa ccaatgattt aatggcgcat tcagctagat tattggaaag
      121 gaccagatgt ccgtctttca aaatagtctt aaaggtttct ttatacttga ggctgtattc
      181 aattgccctt cctagttttg aacccgataa aactgactga cgccggcacc aagcaaagaa
      241 atcttccatt aggttggagc tcttcttgac gtttctgtag tcgttcatca gctggcaaag
      301 cctcccagtc tctttccaag aaaaataact gatcacaata agctaaacct ttagctccta
      361 aggatgattt atccgcttgc ttgggggtcg cttcaaaaaa cttccttctc acatgcgccc
      421 aacatccaac aagtgcagct tcttccagtt gacgataagc ttctagcggt tcgcagttta
      481 ccaagcttag cgtcgccttg ctcctaaacc ttggactgct atcgcatagg cagaactaga
      541 ggactaaagt cctaagttac tgccgcaaca tatcacaatg cacatagcca gaataatctc
      601 ctaggaattc ttgtactact gaaccacttc gacactgatc atggtggtaa agcgtaatcc
      661 cttgtttctc tgatttacct gacaaaaaag tccaatagta agtcagctga ctatcacttt
      721 ctaagacccg ataagaggtt tcatctgcat gaagaagagg ttgttctaac aacttttctc
      781 gtaaaaggtt ataaagggac tctaaatagt attgactcgc cttgatatgc caattagcaa
      841 tttccttacg tgtgattggt aaacccatcc tagcccaatc ttcttcttgg cgataattag
      901 gtaccttcag attaaacttc tgatggatgg tgtgagcgat aatagaagct gagtcaatag
      961 tctcgttata aaggggcttt aggaatagga gctttcacaa ttttatcact cggattttta
     1021 tcactgcatg cttggcattt gtaagcgtgt tggatatgat ctatgcgttt taattgcgca
     1081 ggaataaaga ctaattcttg tcgttgaagg gttgctccaa tctcttttag atctccctga
     1141 caatcagagc aaatgctctc ttctacttga tgatgaactt cttctgaatc aaattgggca
     1201 agaagagctt ggcgtttccc tttagatttc ttacgtttgt aggtaatttc ctctgtttca
     1261 actgggaaca tctccatctt tctcagatgg agactcttcc tcaaaaaggt tgagttgtcc
     1321 agaggggcaa acacttttct cagaggattt tccatagagc ttttgagtca gataagccac
     1381 ttgttcacga agaagggcaa gtgcattggt gagactatca attgtagcac tctgttgttg
     1441 aatgattttc aatcttcttc catgggcttc ccctccttgt tttctacctt tattatacta
     1501 aaaagaaagt cctcatttca atagaaatca cgactttctg atggatttat ttttggagtg
     1561 atagaaaagt ccttcataag ccagtctact tgttcagatg tgagagcttt gacatccttt
     1621 tctgtactgg gccaagtcag tctgccgttc ccaaagcgtt tatatagtag ccaaaatcct
     1681 tgaccatccc agtaaagggc tttaaagcgg tatttacgtc caccacaaaa gagaaaaact
     1741 tgacctgaga aaggatctaa ttcaaagtgg gttttaacca gataagccag tgaatcaatg
     1801 ccttgcctca tatccgtttt cccacatacg agatagacct gccctaggct agatagatga
     1861 attgtcatag agcaacacct tatccaaaag ctgttctacc atttcgagat tgagagattg
     1921 aaaaaaactt acttcaagct tgccaatacg aattttaagc agaatatcat ttctcttttt
     1981 agaatcaaaa ggacgagatt gtggaatctc tacaggaaca ataggttgtg gcattaaaat
     2041 atcctccaat agttttactt tactaatagt atacaggagg aactccatga atgatagata
     2101 ccttgttatg acgcgattac tatattagaa agttggctct ctaattaaat taattctcat
     2161 tatatatatc aaaagaccgc agcttgaaaa ctacggtcta attttttgtc caaatgtaaa
     2221 ccacttggaa ctattattca atttattctt tttagtaaat gttcccgttt taatcccagt
     2281 tacagttttt aatcctctgt aaccgttgat tttacaaagc ttttaatttt tttgcgatta
     2341 ttcccactca actgttgcag gtggtttact tgtaatatcg tagacgatac ggttaacatg
     2401 atccacttca tttacgatac gtactgagat tttttgaagt acttcccatg gaattttggc
     2461 aaaatcagca gtcataccat cgatagaagt gatagcacgg attgcaatcg tgtagtcata
     2521 tgtacgaccg tcacccataa caccgactga acgaacgcct gtgttaacag tgaagtattg
     2581 ccaaatatcg cggtcaagtc cagctttagc gatttcttca cgaagaatag cgtctgattc
     2641 acgaacggtt tcaagtttct cttcagtgat ttcacccatg acacggatag caagtcctgg
     2701 tcctgggaat ggttggcgcc atacgatatg gtctggcata ccaagctctg taccaagagc
     2761 acgaacttca tccttgtaaa gagtattgag tggttcaatc aattcaaact gcatatcttc
     2821 tggaagacca cccacgttgt ggtgtgactt gatagtttga gctgtatccg taccagactc
     2881 gataacatct gtatataaag taccttgagc aaggaatttc acatctttga gcttgcttgc
     2941 ttcgtcatcg aatacataga caaactcgtt accgatgatt ttacgttttt gttcaggatc
     3001 agaaacgcca gcaagtttgt caaggaaacg tttagcagcg tctgctttga cgatattcaa
     3061 accaaactta ccaccgagca tgtccataac ttgatcagct tcgcctttac gaagaagacc
     3121 gtggtctacg aagatacaga tcaattgatc gccaatcgct ttttggagaa gaaccccaac
     3181 gacagatgag tcaacaccac ctgatagacc aagaaggaca cgtttatcac cgacggtttc
     3241 acgaattttt ttgatctgca tgtcaatgaa attatccatt gaccagtcac ctttagcctt
     3301 acaaatgtta agggcaaagt tacgaaggat atcatttccg tatacagaat gacgaacttc
     3361 tgggtggaat tggataccgt aaatgtgttt atctgggttt tcgatggctg cgtatgggca
     3421 gtcagctgat gtacctgtac gaacaaagtc agcaggaatc tcagtaaccg catcaccatg
     3481 gctcatcaaa acagtctgtt catcaggtgt tgattcaaaa agcgctgatg gtgtgtgagt
     3541 tagggttgat tgaccgtatt cacgatttcc agcatcacct gcaggaacaa cttttcctcc
     3601 aagtttatgg gtcaataact gcataccata acagattccc aaaattggaa ttccgagttc
     3661 gaagatttct gggtcaatat caaatgaacc atcttcatat acagaatttg gaccacctga
     3721 tagaataatt cctacaggat tgacttcacg aacttcagca gctgaaattt tatggctttt
     3781 tagttctgaa aaaacaccaa tctcacggat acggcgtgaa atcagctggt tgtactggct
     3841 accatagtcc aatacgatga ttttttctac atcttgcaaa tcagttgaaa tgttgctcat
     3901 ctttttcctt tctcaaaaga aatatctttt ctcaatattc tatcacaaat aagggcgaat
     3961 taccaactaa acaaggcgaa gtttgacttt ttctagttta ttggggtaca atagagaaaa
     4021 gatagaaatg aagtgaaaaa tatgctacct gcttatatga aaatccatga tcagataaaa
     4081 aaggatattg acgagcaccg ttgggctatt ggtgagaggc ttcccagtga aagagattta
     4141 gctgagcagt ttgcggtcag tcgcatgacc ctccgccaag ccgtatctct attagtcgaa
     4201 gaaggcgtct tagagcgccg tgtaggaagc ggcacctttg tttccagtac tcgagtacaa
     4261 gaaaagatgc gagggacaac cagttttact gaaattgtca aatcccaagg taaagttccc
     4321 tctagccagc tcatttccta caaaaaaacc attcccaatg agcaagaagt tgccaagcta
     4381 ggaatttttc caacggacaa tattatccga atggagcggg tccgctatgc cgaccaagtt
     4441 cccctagttt atgaagttgc ttctattcct gaaaaattca ttaaggactt taaaaaagaa
     4501 gaaatcacaa gtcatttctt ccaaaccttg caaaaacatg gctatcgtat cggcaaatct
     4561 caacagacca tctatgctcg ccttgctaaa gaaaagattg cccactattt ggaagttgaa
     4621 aaaggacatg ctattcttgg attgacccag gtttcctacc tagaagatgg tactgctttt
     4681 gaatacgtaa aaagtcaata tgtaggcgaa cgctttgaat tttatcttga aaataattag
     4741 attaccacgc aaaaactctc tgtcacggac aaagagtctt ttttattttt ctaagaataa
     4801 atctttcaaa gaaatcaaag ttacagcaaa caatatcatt gccataccaa gaaaatcaat
     4861 gggataaaat tgttcattca ttattaagaa ggcaaagaaa atcgccgata ttggctcaat
     4921 tgaagccaac aagcttgact tgaccggtcc tatcagactg gctcctttaa ggaaagctgt
     4981 ataggcaaag acagtcccga taaggataat gcctgcaaac gcaaggagaa aatcaagact
     5041 agtcgggata tcggcctgta gaacccctgt aaaaggaagg gcgaccaaac ctgctatgac
     5101 cattcccaca ccaatgagca agctgctccc ccacttttta atcaaggcta tgggtaaaat
     5161 gatatacaga gcataagtca aggcagaaaa gagaccccag aacagaccag caggtgtcat
     5221 ggataactgg tccaactgcc catgtgttgc gatcaggaag gttcctccga tggcgaatat
     5281 gatggaaact atctctccca gtgtcggtgc caccctatcc ttgatacagc tataaattaa
     5341 aattccgaca ggacaaacat actgaagcac cgtcgctgtt cccgcattgg tctcctgaat
     5401 agcagacaga taggcgaatt ggttgagaaa aagaccaatc agagcaaaaa taagaagaga
     5461 cagcaaactc tttctatcct ttaaaaagac cagtatttta tcctttgcag tagcataagc
     5521 caagagcatg agaattccac cagcgattaa aagacgcaag ttggtcaaga ccagagccga
     5581 aattccgtgt gccattaggt attggccact cgttcctgac aacccccaag caataccagc
     5641 cacaactgtt agtaaagtcc cttttaaact atttgacatg tctctcctta ctcttctttg
     5701 cgaatcaagt tcatcacttg attgcggtct aatatccatt gagctctctc gtccttttca
     5761 taggtacgat tcgataggaa aatagtggct tcttgcttct gacgattcca catgataaag
     5821 gtacctgtat agcccgtatg gtctagccaa tctccttcca aattccatgc taaagaacgt
     5881 tccttgtcat ccaaaggaga aaaattttga tttaagtctc ttgcaaaatc atctgctaaa
     5941 tagtgttcta aaaagatttg taaatccttt atagtcgaaa ataaaccagc actcccagca
     6001 tgtctaccca ggagacgagc cttgggatca tgcactatgc ctgcctctac acctctaact
     6061 gttggaacag caagctcaac tggcccaaac ttggtttccg tcattcccca aggtttccag
     6121 acttgatcct ttaaaatcac atccaaatct tgattaaaaa ttctttccaa aataaagccc
     6181 aacagcaaaa aatggacatc cgaataaaga aaggctggct gacttcgtct gttgagatga
     6241 aacatcgctt cctttaattc aggggctgtt aaaagatcac gattaggaat aaaaggatca
     6301 aggtctgttg catgagtcaa gagctggcga atagtgatgt ctggataatc actctcaggt
     6361 aaaaaatcta ttaccagtct atcaatatct aattgaccta tttcccacaa gaaggtacaa
     6421 actgtgccaa ccccaacaac cttgctgaca ctagctagat cataaactag tcctgcctca
     6481 gtctgcaagc catgctctgg gtcactctgg cctaaataga actctgtcca ttgattgtcc
     6541 ttaaaatacg caaaagaggc tccgggataa attcctgcct cgatttgttc ttctattttt
     6601 ttaataatct tggtccactt catacttctt caaaccacaa ttcaacatta tttctatctt
     6661 taccaaggaa gaatttttca gacttaggaa taaaatattc agtagactca aacttctggc
     6721 gaagacttgc tatgtctaat tcattgacca agaacttgag catagataag tcccaggtaa
     6781 ccgtattgtc cacagtcaaa tcctgcccct gagctggaat aaaatcaagg gatgccccaa
     6841 tttcagatga ttccaagaaa ctttcgatat cagttgggag atgtaattcc atagaaatct
     6901 caaatttact taaagaaatt gatgccaaat ctgtttgaaa ttcaggcttt tctcctactt
     6961 ctactagact tgctctgtca tcttccgcat gaatcaaaat caaatcatct tctggtgaga
     7021 aaatttcaaa agcgtagcca ttttgacctt tatataatcg atgaatcgaa tctgttttag
     7081 ataagattcc ttcaatttct aagggatttt ccaccttgac aatcaatcta gctagttttt
     7141 ttcttccctc taccttacga gtacgcatac tgggagcttc ttctaaaacc agcttttcaa
     7201 gacccgtttg gtcacctagt gacagaaagg ccgattcttc taacaaggcc ttcattccaa
     7261 gggtttcaat ataaaatgtt tcatttaatt ttctattatt agcttttaaa gtaggaataa
     7321 tccgtacaat ctgatttaca ttcataaatt cctccgtcac tttttatttt aaaggatttt
     7381 agaatttttt acaagatatt atgctcaaat ttaacattat ttagctattt agtaaagata
     7441 gtctttcaag gattttgaca aagcctgata accagcaata ctgaggtgca gtccatcagt
     7501 tgtatattct tttttgagtt ggcctgcttg gtctgtcaaa caatcaaata ctggcacaaa
     7561 ttccacctgc atataggcag atgcaagctc ttgataggct tgattccagt tctgaatttt
     7621 ttcattcgag cggatataga ctgcctgctg gtactcctct ccctcattga caggcaaaat
     7681 ggaaagcaat ttaatctctg tcaatggata atcgcgagca acggattgaa tgatagcttc
     7741 gagattattg agagcctcat tcacaggaac atcctttccg atatcatttg tcccaatcag
     7801 aagaaaaatt ttatctactg ctccaccata tagatgagca tcaagattct ctagtaacag
     7861 tcctgtctga tagccacgaa ttcctcgatt gacaatcgtc tttgaagtcc caaatagctc
     7921 ctgtagagga taatactcga caatggaatc cccaataaaa agaatgtttg gttctacaac
     7981 agaaatgtga tttaggtgac gatacttagt ttgaattttt tcttgttcct ttaggagcca
     8041 attttctaat aactgtactg ccacttcatt ctcctttttc taaccagttt tccaagactt
     8101 gataaactcc tccttggctg ttggctggtg ctagagcagt cgccacagct ttggctttct
     8161 catcagcatt ttccatcgca taggcaattc cagccatttc aagcatttca acatcatttt
     8221 cactatcacc aaaagccatg atttcttggg atttcaagtc ccagcgcttg agtaattcct
     8281 ccaagcccca tgctttatga atcccagctt ggaggatatc aatgcaacca tagccactgg
     8341 atacagctcg gacacggcca tcaaagagag cattgatttc ttccaaaacc gaactcaaac
     8401 gttcctcacc aacaaccatg ctcatcttga gcacaccacc aaagaggtca gatgttaatt
     8461 catccacaaa ttgcatccgt tggtagaatt tttcaatcat ttctggagtc ataaaacttt
     8521 caagatctgt aaaaatcgta ccttccttga caaaatcacc cttcatcccc gttacaacaa
     8581 actggtcctg acacgctcga cccttgaaat gagccaaagc cttgttgaca atggcgtcat
     8641 cccatgtctg agcctgaatc aattcattgt tttcaaaaat acgagcgcca ttagcaacaa
     8701 ccagaaccac tcgatccacc aagggactca gtagttgtct catgcggtga atttcattgc
     8761 ccgtcgcaat gacaaaacga atgccccttt gatccaactg atctaaaatc ttttccaatc
     8821 gtgggagatc aagctgaccc ctagcatcca gcaaggtccc atccatatct gtcgcaatta
     8881 ccttaatcat catttacttt cctctggatt caagctaata ccacttcaat cccacatgtt
     8941 cattcatttc tttataggct gtatcaattc gttccttagt cgcttcatct aactggtcac
     9001 gatgactgcc acccctctat aaaatcttcc aaaatataag tttggtaatg atacaaggga
     9061 tatccttctg gtgaaaaggt tccctttggt gttcgattga cccaagtagg atgagcttta
     9121 gctgttccga tagttgtttt tccatccttc ttcttgatgg tgacatccat gagaacacca
     9181 cgttcagtcc acttagcatt ctcttcatct cccatagatt caatccgttg attggaaatg
     9241 aagttcccca tttaatagat aatgagtttc ttatctccat ctttttcaac cgttttagat
     9301 ggttcaacaa cgtgaggatg ccctccaaag ataatatccg ctccccaatc gatcatcttg
     9361 tgataaagag ctttttgttc ttcagttggt tccaatcgat actcaacacc catctgaggc
     9421 atgataatgg tgatatctgc ttccttctct gcccgttcga cttcagcctt tatcttatct
     9481 tcgtttaaat ctgaaagata acgattatag tcttcctgaa aaatatactg ctcaattcca
     9541 ttgaaaccat aggaataggc taacaatgca accttgatag cattcacttc cttaatgacc
     9601 agcggagcct gatcacgtgg ttcgtgcgta taaactccga ttggagtgat tccagctttc
     9661 tcaataatat cggccattga aataactccc tcaatttgcg aatccaaaat atgattatga
     9721 gctaaatcca gcacatgata acctgcttcc ttaatagcat ccataacttc aacaggagca
     9781 ttaaagagaa gataacccgc taaataatga tccttattaa tggttccttc aaaatcacca
     9841 atagctaaat ctgcttgctt gagccaagga gtcacatact caaaattttc atgaaagtca
     9901 taggtaccgt cttctttttt agctgaaaag aaaagtccat cgtggtagag caaatccccg
     9961 tgggccataa ttctggcagt tttttcctct tcctactcct gagacttttg cttagtcccc
    10021 tcttgagaaa tagtatctcg tttttgacta gtcaagggat tccttggaag ctttcaaaca
    10081 acaagaccaa gcccattgat aaaccaactg ctagcaagag tatcgccaca aatcccttat
    10141 tgctccactt gcgataactc ctaaaaagtt taccaagccc ttcataaaac gaaaagctaa
    10201 accaccctga tttcgatttt gtcttctttg tatcttcatt ctccctactt tcttatgcaa
    10261 gccttttctt tttattatat cacagataag tatttctttc acaattgaat tgaacttccc
    10321 atctattttc tataaatcct aaatgccata atgctttcaa ttcttgtcat tttgtgatat
    10381 catgtagagg taatgaaagg aaatgaacta atccacagtg gcttattcca agtataccac
    10441 ttgggctttg gcagtagtta actgcactaa acataatata aggagagaaa atgtctgcaa
    10501 tagaacgtat tacaaaagct gctcacttaa ttgatatgaa cgatattatc cgtgaaggga
    10561 atcctactct acgcgcgatt gctgaggaag tcactttccc cctatctgac caggaaatca
    10621 tcctaggcga aaagatgatg caattcctta aacattccca agatcctgtc atggctgaaa
    10681 aaatgggact ccgcggtggt gttggactgg ctgctcccca gttagatatc tcaaaacgca
    10741 ttatcgctgt tttggtacct aatattgttg aagaaggcga aactccacag gaagcctacg
    10801 atttggaagg cattatgtac aatccaaaaa tcgtctctca ctctgttcaa gatgctgctc
    10861 ttggcgaagg agaaggttgc ctgtctgttg accgtaacgt gcctggctat gttgttcgcc
    10921 atgcccgcgt tactgttgac tactttgaca aagatggaga aaaacaccgt atcaaactca
    10981 aaggctacaa ctccattgtt gttcagcatg aaattgacca cattaacggt atcatgtttt
    11041 acgatcgcat caatgaaaaa gacccatttg cagttaaaga tggtttactg attcttgaat
    11101 aaagaaaatc ccgttgcaag acggggtttt gtgttataat agaggcatga aaacaaatga
    11161 tattgtctat ggtgtccacg ccgttaccga agccctcctt gcaaatacag gaaacaaact
    11221 ctacctccaa gaagatctcc gaggtaagaa tgttgagaaa gtcaaggaac tagctacaga
    11281 aaagaaggtg tccatttctt ggacatcaaa aaaatctctc tctgagatga ctgaaggtgc
    11341 tgttcatcaa ggttttgttc tacgagtgtc tgaatttgcc tatagcgagc tagattacat
    11401 ccttgcaaaa acacgccaag aagaaaatcc acttctattg attctagatg gtctaaccga
    11461 tccccataat ctgggttcta tcttgcgaac agccgatgcg accaatgttt caggtgtcat
    11521 cattcccaag caccgtgctg tcggagtaac tcctgtcgtt gccaaaacag ccacaggtgc
    11581 tattgaacac gttccaattg cccgagtgac aaacctcagt caaaccttag ataaactcaa
    11641 ggatgaaggc ttctggacct ttggaacgga tatgaacggt actccttgcc acaagtggaa
    11701 tacaaaaggg aaaatcgccc tcatcatcgg aaatgaagga aaaggcatct ctagcaacat
    11761 caaaaaacag gtcgatgaaa tgattaccat tccgatgaat ggacatgttc aaagcctcaa
    11821 tgccagtgtt gctgcagcca ttctcatgta cgaagttttt ctaaatagac tataaaaaag
    11881 tttccagtca tctgattgga aactttttta tgattaacta tgttctgtga taaacttgta
    11941 ggcttcttga ccagcgatag ctccatctcc aactgctgtt gttacttggc gaaggtcttt
    12001 caagcgaaca tctccaactg caaagatacc gtcgactgca gtcttcatgt ggctatctgt
    12061 cacaatccag cctgcctgat cttggatatt caattcttta acaaaatcgc taagagggtc
    12121 caaaccaaca tagataaaga caccaccgaa ggcttgctct gtcacttgac ctgttttcac
    12181 attttcaaaa acgacagatt ctactctgtt ttcacccttg atttccttca ctacagaatc
    12241 ccagataaag ctgatttttt cattcgcaaa ggcgcgatct tgtaaaacct tttgggcacg
    12301 aagttggtca cgacggtgaa caatggtaac agtcttagca aaacgagtca agaagagggc
    12361 ttcttcaaca gctgaatctc caccaccaac taccaataaa tcttggtcac ggaagaaagc
    12421 accatcacac acagcacagt aagaaacacc acgactgttc agttcttctt ctccaggcac
    12481 tcccaaagga cggtgtttag aaccagttgc tacgataact gtacgtgttt catatgtttg
    12541 gtcatcagtc atcactttct taaaatcacc atggtcttcg acattttcaa cataaccata
    12601 aatgtgctca acaccaagat tttcaagtgg ttcaaacatc ttttcagcca attcaggtcc
    12661 actaatatta gcgtatcctg ggtaattttc gatatcagat gtattattca tctgaccacc
    12721 tggcagacca ccttcaatca aagctacttt tagattgctt cgagcagcat acaaggccgc
    12781 agtcatccct gcaggtccag caccgataat aatagtatcg tacatataga ttccttcttt
    12841 cttgttgtaa ctatctttat tctaactctt tcttgtcaat cacgcaagga ttatgccttg
    12901 aaaacaagaa ttaaactcat aaccgcaaag gataatactg ggacaaccaa gactccaatc
    12961 ataatcatat catagagatg ggcttggcga gccctggctg tcttatcaac tcccgacatg
    13021 gctctcagac caatccaaat ccctaaaaaa atcagaacaa ggatggtggt caagatcaaa
    13081 ctctcgaaat ataaagaaaa tagttgcagt agcatgattt ctctcatttc tatctttttt
    13141 aaagagtaaa ctcagctagt ccaactaact gagttttcct ttatctatta tatcaaatat
    13201 aagtccgttt gtaactagcg aagaattctt ttgtccgctc ttctttaggg gtgtggataa
    13261 tctcatccgg agttccagac tcgatgattt tccccttatc taataagaga attttatccg
    13321 caacttgggc tacaaaggac atgtcatgac tgaccaaaat catggtctga cctgacttag
    13381 cagcatctgc aatagacttt tctacttcac cgaccaattc tgggtcaagg gctgaagttg
    13441 gttcgtctaa gagcaaaaca tctggtttca tagcaagcgc acgcgctagg gcaacccgtt
    13501 gcttctgtcc acctgataaa tggcgaggat aatggttttc acggtccgaa agcccaacct
    13561 tagccaactc ttccttggca atcttagtcg cttcttggtc agataatttc ttgacaacaa
    13621 ccaagccttc tttcacatta tcaagtgctg ttcgacgttc aaataaatta aactgttgga
    13681 aaaccataga caacttacgg cgtagggcaa ggatttcttc ttgagtgatt ttagaaaaat
    13741 caactgaaaa accatcaatc tgaatagagc cactgtcagg tgtttcaaga taattgagac
    13801 tgcgaagaaa ggttgatttt ccagctcctg aagaaccaat caaggctaca acttcccctt
    13861 tttgaatatc caagttcaga tgatccaaga cagtctgtcc tgaaaaggat ttgcttaaat
    13921 tcgaaatctt aatcattaac gaaggtctcc tttcacatct gtttgcactg tatcaggtgc
    13981 agaaatagcc atttttctct cgatgaaacg accgaggctt tcaattccga tattgactac
    14041 ccaataaaca agggcaacag agatgaagcg ttcaaaatag cgataatcag ctccacctag
    14101 aatctgagct tgggcaaaga cttccacaac acccgcacta aaagctagag atgttccctt
    14161 ggtcaaaccg atgagggaat taatcaaggt tggagtagct accaccgctg cattaggaat
    14221 aatcactcgt cgataaactt gcgctcgggt catacccaga ctgcgcgccg cctcaatctc
    14281 accaggatta actgagagaa tggctgcacg aatggtttca ctagcataag ctgcctcatt
    14341 aaaggcaaaa gcgacaatcg caaaagctgc agctggaatc gcattgatat tgagaccagt
    14401 tccccattgc tgattgaggg ctttcaaagc caaagggatt ccgtagtagg tcaacatgag
    14461 ttgcaccaaa atcggtgtcc cttttaagaa actaacaaag aaggcctgca agggatataa
    14521 aatcttgaca cgattgatct tcacaatggc aaaaagaagc gccaaaacca agccaaaaag
    14581 ggcaccacca attgtcaaca taattgttgt tggaagttgt tggacaattc tagggattcc
    14641 atcaaagacc gaacgtaggc taaacagctt gccatccgga atcaattgca tcaagttttg
    14701 gtaccaatct gatgctaaaa tcgttgtaac attcataaaa acatcctctt ctgataatga
    14761 ttcattctac catgcttctg ccgtcaatga aattatttgc tacggtcaga tacagacttt
    14821 gtctacctac tagtttatca tactttgaaa cagggaagtt atatatttta tctatcaaag
    14881 agatagataa aaactatttc agtcccagtt cttcataaga ttttcgataa ccgatttgct
    14941 taacagttcc attttctact aaaatgggcc gttttaacaa cataccgtca cttgctagca
    15001 actcagccgc ttcttggttt gacaaacttc ctaccttatc ttttagccct aattcacggt
    15061 atttgatacc actggtgttg aaaaattgct tcaattcaaa tcctgaggtt tctagccaat
    15121 tcaaaatgac ttcttggcta ggtgtttctt ccacgatatg gacggcttta tagtccacac
    15181 ctaattgatt taattcttgt tttgcttttt tacaagttga acatttgggg tattcgataa
    15241 attctaacat gtgcttctcc ttctatttgt ttatatcttt aaaatctacg ccttcatgct
    15301 ccaagagcca agctttcttt tccactcctg cagcatagcc tgtcagacgc ttgcctgctc
    15361 ccaacacacg atgacaaggt actaggatag accaaggatt gcgtcccact gctccaccaa
    15421 ttgcttgagc agaagccact tgcaggtctt gagcaatttg tccataggtc actgtctgac
    15481 cataaggaat gccctgtaaa tagtcccaaa ctctcttttc aaaattcgtt ccgattggcg
    15541 ccaagagcaa gttggataaa tcctgaggct tgcctttaaa gtaatcatct aagcaagcaa
    15601 taactgggtc taaaatagga tgactaacaa cttcttctat cgtttcatct cctagtcccc
    15661 tctcaaaatg cttctgctcc tgaacccaaa ttccatacaa ataatggtca tcagctacaa
    15721 gtgatagaat accaattggt gaggagtaga gtatttttac atacttcttt tgcattattt
    15781 ctttaatttt tgataggcca agcgttcgcc atctactggc accttaccaa cttgtttaaa
    15841 accaagtttt tcaaaaatat gttgcataac cttgttttca gcatgcgtat ctgagcgaaa
    15901 atcaagataa tcaaaacctt caatcaagcc ctctaagaag gtttgagcaa ctccttttcc
    15961 ctgcacatct gctgccacag caatacggtg aaagactaga tactctgact ctccagcttg
    16021 ccagtttccc tcataaatag cttcataggc ctcctctgga ctcttggtca cagcagcata
    16081 ggctagcagt tctccctctt ccaaggctac gtaggcttgc cctgagatga tatcatcgat
    16141 aataacatct gcatttggat agccattttg ccactggtca ctaccagcat ctgctaaaca
    16201 ttttttggca tcctccatca cctgcatgat ggcatctact tcatttggaa aagctaaacg
    16261 aatttccatc ttttttcctc atttctgact agtttctccc atcatagcat aatttaagta
    16321 tttctacaag cagttaaaac ttgactttgt gtttttgtta ttttataatc tagttatcaa
    16381 aactatataa aaaggagttg aaaatgaaaa ctaccttttc ctacccaaaa tgggcagaaa
    16441 ttccaaacat tgacctctat ctggaccagg ttttgctcta tgtcaatcag gtctgcgccc
    16501 ctatctctcc taataaagac aagggcctaa cagcatctat ggtcaacaat tatgtgaaaa
    16561 atggttacct gacaaagcct gacaaaaaaa aataccaacg ccaacagatt gcccgtttga
    16621 ttgctatcac aaccctcaag tctgtatttt ctattcaaga aatagcccag acacttaata
    16681 ctctacaaac tcaagcaagt tcagaccaac tctacgatgc ttttgtggac tacatgaacc
    16741 aaggaattga cccagctaac cctattatcc aaaccagctg ccaaaccgtc aaactctatc
    16801 atcaaactct agacttaatc gatcatactc aagaggaggt aatccaatga acactagtct
    16861 taaactcagc aaacaactca gttttggaga ggagattgct aatagcgtga cccatgctgt
    16921 gggtgcagtc atcatgctta tcttgctgcc tatttcatcc atctatagtt atgaagcaca
    16981 cggattttta tcctctatcg gcgtttccat tttcgtcatc agtctctttc tcatgttcct
    17041 atcatccacc atttatcact ctatggccta tggttcgacc cacaaatatg ttttgcgaat
    17101 cattgaccat tctatgattt acgttgccat tgccggctca tacacgcccg ttgtcttgac
    17161 cttgatgaat aactggtttg gctatctgat tattgtcatc caatggggaa cgaccatctt
    17221 tggtattctc tataaaatct ttgctaaaaa ggtcaatgag aaatttagcc ttgctcttta
    17281 cctgattatg ggctggttgg ttctggctat cattcctgcc attatcagtc aaacgacacc
    17341 cgttttctgg agtctcatgg taactggcgg actctgttat acagttggag ctggatttta
    17401 tgccaagaaa aaaccttatt tccacatgat ttggcatctc tttatcctag ctgcgtccgc
    17461 acttcaatac atcgctattg tttattacat gtaaaaaagt tgagaaattc aatctcaact
    17521 tttttcttta cacatattga taaagtactg gtgcaagcgc acatcatcag tcaattctgg
    17581 atgaaaagaa cttaccaaca tatttttttc ttgggctgca acaatttgat tgttcactgt
    17641 tgctagaatt tctacaccct caccaacact actgataatc ggaccacgga taaaggtcat
    17701 tggaatcttg ccaactccct tacattctgc ttccgtgtag aaacttccta attggcgccc
    17761 ataagcatta cgctcgacca ccatatccat agttcctaga tgactctctt tctgagaagt
    17821 gatttcctta gccagcaaaa ttaagcccgc acaggtccca aacactggta agccagatag
    17881 aatggcttct cggatgggaa gtagcatgtt ctggtcacgt aagagcttgc ccatggttgt
    17941 agactcacca ccaggcaaaa tcaaacccga caagtcactc tgatcttgct gaaaatcatc
    18001 tagatttctg agttctacac tctcgacacc taattgatct agcacttttg catgttctgc
    18061 aaaggcccct tgcaaggcca atattccaat tttcatctat tttcctcgtt cagccatgag
    18121 aatttggatt tcattttcat taataccaac catggcttct cctaaatctt cagagatttg
    18181 agctaggatt tgaggattac ggaagttagt cacagcctta acaatggcac tcgctcgttt
    18241 aacaggatct cctgacttga aaatacctga accgacaaag accccctctg cccctaattg
    18301 catcattaac gcagcatctg ctggcgttgc aacacctcca gcagcgaaat ttacaactgg
    18361 caattttcca tgttcatgaa catattggac caattctaca gggacttgca aatccttggc
    18421 agcaacataa agctcgtcct cacgtaagtt ttgaatgcgg cgaatttcct gattcatcat
    18481 acgcatatga cgaacagctt ggacgatatc ccctgtccct ggttctcctt tggtacgaat
    18541 catggaagca ccttcagcga tacgacgcaa ggcttcaccc aaatccttag caccacagac
    18601 aaaaggaact tggaattctt tcttgtccac atggaaacgg tcatcagctg gagatagaac
    18661 ttcactctcg tcgatataat caatttcaat agcctctaaa atctgagctt caacaaaatg
    18721 cccgattctg accttagcca ttactggaat actaaccgct tcttggattt ccttaatcat
    18781 ctttgggtcg ctcatgcggg aaactcctcc agctgcacga atatcagccg gaattcgttc
    18841 caaggccatc acagctgccg caccagcagc ttctgcgata cgagcctgtt caggattctg
    18901 cacatccata ataacaccac ccttgagcat ctgtgccaag tttttattta gttcataacg
    18961 attttcagtc atttgtttta tcctcatcat ttgtattggt agctaccttt tcattttaag
    19021 tcagaacaga atgaagcaca agataaaaaa actataattg tatggggaca gattggctaa
    19081 aaactatctg accttaactt aaggccagat agctcattca tttttatttt tcagccgtaa
    19141 gggcagccat tgtgatgtag ttgtatggtt tattgaagtg tggcaagaag aagaggtctg
    19201 tcaatgccaa tttatcaatt gtcacatgct cttggatagc aagtgagaac atgtggattc
    19261 ccatgctaat tgcaatatca tgtgaaacca tttgggcacc aagaatttca cggctatctt
    19321 tgtcaaagac aatcttaatt gctacttcat ggttgtcatg tttcatgaat tctggttttt
    19381 gaagatcgtt aaagcctgtt tcagttgcgt tgtaaccagc agctttcgct ttttcaagag
    19441 tcaaaccagt tgaaaccatg tgaagaccgt agattgagat accatttgaa ccttgaacac
    19501 cgattccttc caattcatgt ccacaagcgt tgtaggcacc aacgatacca gtgcgaacag
    19561 catttgaagc aagagcgata tagcttgtat ctttacgagc attgtcataa acagtcgcac
    19621 agtcaccaac agcgtaaacg cctgggatag atgtttcttg tttcttgtct acaaggaagg
    19681 caccgttgcg gaagagttcg atcttaccat cagcaagggc tgtgtttgga cggaaaccaa
    19741 ctgcaaggat aaccatatcc acgtcaaagc tttctttgtc agtaatcaag cgttcaactt
    19801 taccatcacc ttcgattgct ttaacagttt gacctagagc caagcggatg ttgtgatctt
    19861 ccaagttctt cgccatcatt tgtgtgaagt ctttgtcata gtaaccgttc aagacagtat
    19921 caacgatatc aacaaggaca acttcttttc caagacgttc aaaggcttca gcaagttcaa
    19981 caccgatgta accaccacca acaacggcga tacggtcgag atgttggctc ttgtcagaaa
    20041 gtttattgat aacttcttca gcattttggt acaatttcac gaattgtacg ttttcaagag
    20101 ttgctttaaa ttcgcggttt cctttaacaa tttcaacacc ttcgattggt ggcaagattg
    20161 gtgtagaacc tgtagcgaaa atcaatttct cgtatgattc tttgtgttct tttccttcaa
    20221 cttctgctgt aaccactttg ttatcatagt cgattgaaag aactggtgaa ttcatataaa
    20281 ccttagcacc tttagcttct aatttgtctt tatcagaata gaacaagcct tcagcaccgt
    20341 caatttgttc accaatccaa agagccattc cacatcctag gaaagagatg ttagagtttt
    20401 ggtcaaatac aacaatttcg ttctcatttc caaaattatc caacatggta ttgatacatg
    20461 ctgtaccagc gtggttagca ccgactacaa cgattttact cataaaaaat ttcctgcctt
    20521 cattctaaat ttactttact agtataccat ttaccgttag cgtttacaag ggggggacta
    20581 ttatttcagc attttttatc aaaaataatt ccccatttat cctgttttca agcctcatga
    20641 attttatgag catatttctt gactttttcc aaattttgtt tgtgaaaatt ctaactttat
    20701 ggtattataa taacatgaaa ataaaatgta agggcttcaa tttagatgat tatttgatat
    20761 tgcaacttat tttctataag agaaaggagt tggtagcttg actcttcgtt cacattctga
    20821 acggctaatg gggactacta tcactatttc attagtggat gagcaagccg atatctttct
    20881 ccaaaaatcc tttgacttgc tcaaagagct tgaataccgc ttcaacgcca atagtcaaga
    20941 atctgagttg atggaaatca attatcaagc aggaatatcc cccgtcacag ttcatccaga
    21001 cctgtttgag ctgatttcac ttgggttaga gcatagccta gcgctctcta gccacctcaa
    21061 tatcagcatt ggtcccttaa ttcaaacctg gcgtatcggt ttttcagatg ccaaggtcgc
    21121 ccagcctcaa gaaattgaat cggtgctgcc tctaatcaat cctcatggta tcgagttaga
    21181 ttcttctact tctactgtgt ttttaaaaca gaaaggaatg aagatcgatc taggttgttt
    21241 agccaaagga tacagtgcgg ataaggttgc ccaatttctt aggaaagagg gggtgacttc
    21301 tgccttgatc aatctgggag ggaatatcct gaccattgga aaaaatcagg caagagggga
    21361 taacccatgg caaatcggga ttcaagaccc agccaatcct aggggaaatc atttaatgac
    21421 catccctgtt gtcaataaat ctgtcgtgac ttcaggcatt tatgaacgtc acctgaccgt
    21481 cgatggacaa gattaccatc acatttttga cagtcaaaca ggatatcctg ttgaaacgga
    21541 actagcgagt ctaacaatca tctctgataa atcagtcgat ggcgaaatct ggacgactcg
    21601 actctttgga gaaagacctg cttctatcct ctggcaagtc gaaagtttgg agggcatcga
    21661 agtcatcctc atcgataaag aaggccacct aagctgttct tcaggaattc ctactctata
    21721 gagacaactg tttcaatgga attttaaaat tgtattatgt aaaaagagaa aggaaatatc
    21781 atgttaaaac ttattgctat tgttggaaca aattcaaaac gttctacaaa ccgtcaattg
    21841 cttcaataca tgcaaaaaca ctttgctgac aaagctgaaa ttgaacttgt tgaaatcaag
    21901 accattcctg tcttcaacaa accagctgac aagcaagtac ctgctgaaat attggaaatt
    21961 gctgctaaaa tcgaagaggc agatggcgtt attatcggta ctcctgagta tgatcactct
    22021 attccagctg ttttgatgag cgctcttgct tggttgtctt atggtattta cccacttttg
    22081 aacaaaccaa tcatgattac aggtgcttct tacggtacgc ttggttcatc tcgtgcccaa
    22141 ttgcaacttc gtcaaatctt gaatgctcct gaaatcaagg caaatgttct tccagatgaa
    22201 ttcttgctca cacactctct tcaagcattt aacccaagtg gcgacttggt tgaccttgat
    22261 gttatcaaga aattggatgc catctttgat gacttccgta tcttcgtgaa gattactgag
    22321 aaattgcgca gtgcgcaaga attgcttcgc aaagatgctg aagactttga ctgggaaaat
    22381 ttgtaagata ggagaccgaa agaatgaaat ttgttggact tgttggatca aactacgatc
    22441 aatcatataa ccgcaaactc ttggaattta tccgtcgcaa tttcaaattc aaatttgaat
    22501 tagaagtact tgaaatcgac gaagttccaa tgtttaacca agacgaaaaa tgggacgaaa
    22561 gcttccaatt gcgtttcttg tataacaaga ttacacgtgc tgatggtgtc attatcgcca
    22621 ctcctgagca caaccacact atctcagctt cactcaaatc tgtacttgaa tggctttcat
    22681 acgaagttca tccatttgaa aacaagcctg ttatgattgt gggtgcatca tactatgacc
    22741 aaggaacatc acgtgctcaa gttcaccttc gtaaaatcct tgatgctcca ggtgttaatg
    22801 cctacacgct tccaggtaac gaattccttc ttggtaaagc taaggaagct tttgataaca
    22861 acggaaatat caccaacgaa ggcactgtta aattccttga aacttgctta gataactttg
    22921 ttaaatacgt aggagtcgtt tcgaaattga aaaaaccaaa accaatcgaa tcagaagact
    22981 tggattgtgg aaaaccaatc gctacaacca tcacagaagt tgaccctgac gatccagaat
    23041 gggtagaaaa agttgcagca atcactggtg ctgtttctgg tgatacctat gtcaaattgg
    23101 accacggtat cctaacagtt aaccaaattg atatgttctt gaaagctatg ccatttgaat
    23161 tgacatacgc tgacgacaac aaccaattcc tctactacaa caacgctcac caagatccag
    23221 acactatgtt cgctaaacgt gtaccacctc aatcaggtag ccgtatgtcg actgttcatg
    23281 gttctcttcc accagcacgt atgaagaacg tagagtgggt tatcggaaca cttcgcaacg
    23341 gaaaccaaga atacgtccgt acgatcgttc caggttctcc tgcaggtgtt atcaacactc
    23401 acaactacca agcaatgtac tatcctgatg gatcatacgc tggtatcaat gaaatcgtct
    23461 ttaacttcca accatggctt gactggtacc taaaagagac tggtcaacgt ttggtgggtg
    23521 gtagcggacc atttgctcct gctgccggag gtcatggaga cgccgatgct acttctggcg
    23581 cttctgattc aggggatgct ggaggccacg gtggtgacgc agacgctaca gccggtgcaa
    23641 gtta
//
LOCUS       DAVBIC010000035        23576 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.035, whole genome shotgun sequence.
ACCESSION   DAVBIC010000035 DAVBIC010000000
VERSION     DAVBIC010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23576)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23576)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23576
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.035"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            387..647
                     /locus_tag="VQ664_001383"
     CDS             387..647
                     /locus_tag="VQ664_001383"
                     /inference="COORDINATES: protein motif:HMM:NF012235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2789538.1"
                     /translation="MSGGETKRVALAKIILKNPPLIFADELTASLDSTTSQGIMKLLL
                     GMKNKNRLIIIATHNPDIWNQADEVINLNQLLQSIYIFYILK"
     gene            complement(751..1221)
                     /locus_tag="VQ664_001384"
     CDS             complement(751..1221)
                     /locus_tag="VQ664_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HET2789539.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQTLLAENDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(1238..3511)
                     /locus_tag="VQ664_001385"
     CDS             complement(1238..3511)
                     /locus_tag="VQ664_001385"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HET2789540.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELEVKLPHKIELEKPQLNLVQPQGKAELIAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLASDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHIHKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCETFSLGQEEQ
                     AIQNQYPDKDFERYGKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
     gene            3858..6959
                     /locus_tag="VQ664_001386"
     CDS             3858..6959
                     /locus_tag="VQ664_001386"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HET2789541.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDDQGVNLRFLALSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVPYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQERFPQALDNLEKLISG
                     ISYDLDTSLKLPRFNPARPAVEELRERAELGLVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     ETEGIHLKIEEIDLEDKETLALFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDPVLEDILAPTYGIMLYQEQVMQVAQRLAGF
                     SLGKADILRRAMGKKDASAMHEMRASFIQGSLEAGHTVEKAEQVFDVMEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQVMLNSSNSDYLIDALEAGFEVASLSINTIPYH
                     DKIANKAIYLGLKSIKGVSNDLALWIIENRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQESEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQADD
                     SKKKLDVTLFSDLYRQVGQEVREGAFYYIKGKVQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHESDQEISRILEQFKGPIPVIIRYEEEQKTIVSPHHFVAKSDELEAKLNEIVMKT
                     IYR"
     gene            7041..8048
                     /gene="pfkA"
                     /locus_tag="VQ664_001387"
     CDS             7041..8048
                     /gene="pfkA"
                     /locus_tag="VQ664_001387"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HET2789542.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEAGFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     S"
     gene            8105..9610
                     /gene="pyk"
                     /locus_tag="VQ664_001388"
     CDS             8105..9610
                     /gene="pyk"
                     /locus_tag="VQ664_001388"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HET2789543.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATSSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
     gene            complement(10342..10567)
                     /locus_tag="VQ664_001389"
                     /pseudo
     CDS             complement(10342..10567)
                     /locus_tag="VQ664_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838792.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            11415..12287
                     /locus_tag="VQ664_001390"
     CDS             11415..12287
                     /locus_tag="VQ664_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HET2789544.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            complement(12433..12777)
                     /locus_tag="VQ664_001391"
                     /pseudo
     CDS             complement(12433..12777)
                     /locus_tag="VQ664_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            12920..13210
                     /locus_tag="VQ664_001392"
     CDS             12920..13210
                     /locus_tag="VQ664_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789545.1"
                     /translation="MELKDFTEKEQEMIKKRLTMSNISDKETTEKILALVPQDLIKRI
                     PFFVRKHATTRTIKRISIEYPELYAVAQTSGEIPEKNAKNCVRLSQLSLNKR"
     gene            13234..13950
                     /locus_tag="VQ664_001393"
     CDS             13234..13950
                     /locus_tag="VQ664_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET2789546.1"
                     /translation="MKKYFIGGLGSNAYHSKDFLQELDSQVYFLNPYEKHLRDETELK
                     SWFKNEIVEEESICLIGHSIGGDLARYFASEFEEVKKLILLDGGYLDLDKILPLDTEL
                     EETKNYIKSQIISDLDVLTSKEKSEAKHWSENMEKAVRQSYHWNVEYNRYELAINYEN
                     IEAILRLRRKIQAFKREVGDTLFISPRYPNEATWREEALKELPDYFDTIFLENFGHEL
                     YTQAPKEIASLMNEWLAYFL"
     gene            complement(14079..14894)
                     /locus_tag="VQ664_001394"
     CDS             complement(14079..14894)
                     /locus_tag="VQ664_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HET2789547.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTDLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWITAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(14891..15796)
                     /locus_tag="VQ664_001395"
     CDS             complement(14891..15796)
                     /locus_tag="VQ664_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HET2789548.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGMLFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKVFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMILAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLVYSLLIGVIL"
     gene            16194..18323
                     /locus_tag="VQ664_001396"
     CDS             16194..18323
                     /locus_tag="VQ664_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HET2789549.1"
                     /translation="MDKKYEKISQDLGVMLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIVDLEKEAEKFVCEGFATGKEALTGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQAKDESLDEKQVFQIYYDFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFATRFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRAQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYTAVKELFKRL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVSVGD
                     LVTVWVKKIDTEREKVNLSLLAPNETD"
     gene            18310..18759
                     /locus_tag="VQ664_001397"
     CDS             18310..18759
                     /locus_tag="VQ664_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HET2789550.1"
                     /translation="MKLTDYVKQVSLEDFGRAFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQKLGMEVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPLKLYRCQSCQQRYQRKRRIDTKRYRCGLCRGKLLLINQPED"
     gene            18818..19090
                     /locus_tag="VQ664_001398"
     CDS             18818..19090
                     /locus_tag="VQ664_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HET2789551.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
     gene            complement(19444..19635)
                     /locus_tag="VQ664_001399"
     CDS             complement(19444..19635)
                     /locus_tag="VQ664_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789552.1"
                     /translation="MKHKEHILIGLLYLLSPFIGQLLVEHTHFIGTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
     gene            20063..20821
                     /locus_tag="VQ664_001400"
     CDS             20063..20821
                     /locus_tag="VQ664_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2789553.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVVTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFDEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            20823..22811
                     /locus_tag="VQ664_001401"
     CDS             20823..22811
                     /locus_tag="VQ664_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2789554.1"
                     /translation="MFRLTNKLAVSNLIKNRKLYYPFALAVLLAVTVTYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVVFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQTKVVITVLV
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKKGRFLPLQTILGSISLGIGYYLAL
                     TVKDPLTALTTFFIAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSSESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDKGYSVKEKEVLRYSNFGIANQEGTKLTIFEKGQNRVQPKTVFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNEGVKEQKALTLNDHQFSVKEEFTKDFIVNHVPNQF
                     NILTADYNYLVVPDLQAFLDQFPDSAIYNQFYGGMNVNASEAEQLKVAEEYEKYLQKF
                     NAQLNTEGNYVYGSTLADASAQMSALFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTINKQVLTVFFLPLLFAFLHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(22853..23497)
                     /locus_tag="VQ664_001402"
     CDS             complement(22853..23497)
                     /locus_tag="VQ664_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HET2789555.1"
                     /translation="MLRAGVLDANDGIISIAGVVIGVASATTNIWIIFLSGFAAILAG
                     AFSMAGGEYVSVSTPKDTEEAAVSREKLLLDQDRELAKKSLYAAYIQNEEFKTSAQLL
                     TNKIFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFLRSLPPMLSVTIFPSDYR
                     IPATVLIVGVALLLTGYTSARLGKAPTKTAMIRNLAIGLLTMGVTFLLEQLFSI"
BASE COUNT         7236 a         4241 c         4975 g         7124 t
ORIGIN      
        1 atgatgtcta aaatctggat attagggtct ttaatgtcta gtaattttgt gataaaatgt
       61 aattgttcca tatgaatctt tctaatgagt tgttttgtcg cttttcatta taggtcatat
      121 gggacttttt ttctacaata aaataggctc cataatatct atagtggatt tacccactac
      181 aaatattata gaaccctttt ttattgacag tatcaggata tctttttcaa atttttggtt
      241 tgttagataa tgaaaatgtt tctatcaatc tagatttagg attaataaat cgtaaatgta
      301 attataaaga aaaagataag ttaaaaaaag atgtattagc aagagttggt ctaactcata
      361 ttcatctata acaaaagata tatgaattgt ctggcggtga aacaaaacgt gttgctttag
      421 cgaaaatcat tcttaaaaat ccaccattaa tattcgcgga tgagttgact gcatcactcg
      481 attcgacgac ttcacaagga attatgaaat tgttattagg tatgaaaaat aaaaatcgtc
      541 taatcatcat tgcaactcat aatcccgata tttggaatca agcagatgaa gttataaatt
      601 taaatcaatt attacagtca atatatatct tctatatttt aaagtaattt tatctgaatc
      661 cgttaagaga ctattgtccc aggctctttc tgatgttaaa gactttctac caggtttttt
      721 aaaagcataa ttgttagttg tagtcattta ttattcttca aagaaaaatg gtggggcgaa
      781 ttttttcagt tcttcaaagc acttttgagc agtatctgca tcttcacaga tgataagaca
      841 gacatcatta ccacaaaggg tagcgatagc gtcagggaag ctcaaagtat caatgataga
      901 accaaaggat tgagccagtc caggaagggt ttttagtagg acttggtgtt gaactgggcg
      961 catccagaca agggcgtctt ccatgtagag ttcgagacgt ttttcccatt ttgagatgga
     1021 accattgtta agaacataat aagcgctatc ttcttcgcgg acttttgata ggttcatatt
     1081 tttgatgtcg cgtgagaggg ttgcctgagt tacttgaatg tcgttctcag caagaagggt
     1141 ttgcaactca gcctgtgtat gaatcttgtt ttttgtgata agagcgcgta taagttggtg
     1201 gcggtgttct gatttattca taataatgta actcctttta gcaaggtaag gtaagcatgg
     1261 actgagcgag gtcgacagtc aagtggtagt ctgtattgtc acggatggtg atttcaaagt
     1321 cagtagtata gaggactaaa cggagagtgt ctccttcttt tagcttgtaa atagttggct
     1381 gcagttcaaa ttgaacgtcc atccattcat ctgcagtaat atcctctact aacagtaaat
     1441 catttctatt ttgtaaatta aggtaacctt ttgtcacgac tctttgtgcc tctggtctaa
     1501 atggcaattc acagagattt tccaacatgt gatagcgacc gttgtcaatg gttctagcac
     1561 ttaaaatagc tggataaggt tgtaggtatt tcttttgccc aaattctagc agttgggcag
     1621 ataagagccc cttgtttgta ctggatttga tacgaagatt gagctgagcg cgaccgttta
     1681 ggtggagatc tttagtcaca ggaaggttaa tagtaatctg attagctttc ccttgataga
     1741 gctctgtatt gaaggtttgg tatgtcttac catagcgctc aaaatcctta tctgggtact
     1801 ggttttgaat agcttgctct tcttgaccaa gtgagaaggt ttcacagttt tcttgcccac
     1861 cgaagttatc aagtgataac caagtctgtg gagctgtatt gtcctgccag ataacagtag
     1921 gaagttgaaa gtctgtttcc tgtcctagta atttcttggt caataaggca tttatggact
     1981 cacggaagtc aattgattgc caattgttca tgtaaacatg ggcaccatta tggaaaaaga
     2041 gatgcttgtg tatatgagta ggaagagcat ggaacatctg gtaaacatga agtggtttga
     2101 cattccaatc ctgagaacca tgagtaaaga caacctctgc ctttacttta tgggcattga
     2161 gcagataatt gcggtcatgc caaaactgat tgtagtcccc agtttttcgg tctagttgag
     2221 ctttcacttt ttctaagtca gcttggtgag cttcattgcc acggatatag tcgctagcca
     2281 agagattacg agaataggtt aactcagcaa gggagtcaaa gtcctcacct ggataaccac
     2341 ctgggctagt caccagaccg ttttcacggt agtagttgta ccatgatgaa attcctgcct
     2401 cggcaatgat aacttctaaa ccatcgactc ctgtagtcgc aagaccattg gacatggtac
     2461 ctagatagga aagtcccgtt gtagcaactt ttccgtttga ccaatcagcc ttgacttgac
     2521 gctggcgcgt gtgatcagta aaggcacggc aacggccgtt aagccaatcg atgacatttt
     2581 tataagcctc gatttgctgg tagtctccat tagtcatgaa acctgtcgag tctttggtac
     2641 caacacctga gacatagaga ttggcaaagc ctctcggaag gaagtagtcg tttagtgtat
     2701 agctagagtt gatgtgagtt agcttttcct cagcctctgc tataagctca gctttacctt
     2761 ggggttggac gagatttagt tgaggtttct ctagctcaat cttgtgagga agtttaacct
     2821 caagctcgcc ctccatcttg tagagagcct tgtcactagc cttgtcattg gttccctgat
     2881 gataagggct ggctgtcatg atggcaggga tttttccatc aaaacgaggg cgaataatgc
     2941 taacctttac taggtctgat agcccttttt ggtcagtatc gacacgagac tcaacgtaaa
     3001 cgacttcacg aatgacatcc tggttagaaa aagtagccaa actcttgccg ttaaagtagt
     3061 ggtagtcatt atcctccgga ataagaccat cactaacaag ttggtcgata agagtatttc
     3121 cttttttggt gcgagtattg agtaactgat agagattttc aatcaagtca ccatatataa
     3181 tgggaaatcc agtttcttta cgaaaaacgt cactatcttc gaagtcaacc aaataagaaa
     3241 agcctaaaag ttgaaaagca acagtataaa aaatatctgc tgtcagttca tcttctgatt
     3301 gaaaaaatgt cagcaggtct gtttttttat cagctgctag gatagaaagt gggtagttgg
     3361 tgtcttgata agtgaaaaag aaacgacgta aaaaggtttc aagtgagtct ttgtgattgg
     3421 ctgtattttg taaatcaaag ccacattttt ttagttcaga taagacattt tcttttggaa
     3481 aattgatata actatattga ttaaaacgca tagaacctcc atatagaatg acagttaagg
     3541 ttattatatc aaaaaaaaag cagaaaggga attgttaact tcaaaaggaa ataatccaat
     3601 aaaaatgaat aaagtactaa attcaatata gagaacagag taacaataag aataaataga
     3661 tagggtataa aagttctagg agatttatat tatatgcttt ctgtttttat atacaatata
     3721 gtataaatat aaaaatgatg acaaaaatac aaatgaatag aaaataaatt agtaagctga
     3781 tgaaattttt ctcaagagaa gccatttata ggtgaaaatg gtataatata gtgagaagga
     3841 tagaggagaa gtgtaaattg atcgcacaac tagatacaaa aacagtctat agttttatgg
     3901 aaagcgtcat ttcgatcgaa aagtatgtga gagcagctaa agaatacggc tacactcatt
     3961 tggctatgat ggatattgac aatctttatg gcgctttcga ctttctagag attacaaaaa
     4021 aatacggcat tcatcctttg ctagggcttg aaatgacagt gtttgtagat gatcagggag
     4081 tgaatttgcg ctttttagct ctatctagtg tgggctatca gcagttgatg aagctttcga
     4141 cagccaagat gcagggggag aaaacttggt cagtcctgtc ccagtacctg gaggatatcg
     4201 cggtcattgt gccttatttt gatagagttg agtcgttaga actaggctgt gattactata
     4261 taggggttta tccagaaaca ctagcaagcg aatttcatca tcctatctta cctctttatc
     4321 gggtcaacgc ttttgaaagc agggatagag aagttcttca agttttaaca gcgattaaag
     4381 aaaatctacc gctcagagaa gttcccttgc gttcgagaca agatgtcttt atatcagcaa
     4441 gttctttaga gaaactattc caagagcgtt ttccgcaagc tttggacaat ttagaaaagc
     4501 ttatttcagg catttcttac gacttggata ctagtctgaa actgcctcgt tttaatccag
     4561 ctagaccagc agtagaggag ttgagagagc gtgctgaact ggggcttgtt cagaaggggt
     4621 tgactagtaa agaatatcaa gatagactag accaagaatt gtctgttatt catgatatgg
     4681 gctttgatga ttatttcttg gttgtttggg atttgttgcg ttttggacga tcgaatggct
     4741 attatatggg aatgggaagg ggttctgcag taggcagttt ggtttcttat gccttagaca
     4801 tcacggggat tgacccagta gagaaaaatc tgatttttga acgctttctt aatcgtgaac
     4861 gctataccat gcctgatatt gatattgata tcccagatat ttatcgtcca gattttatca
     4921 gatatgttgg taataaatat ggtagtaaac atgcggcaca aatcgttact ttttcaacct
     4981 ttggagccaa gcaagctctt cgagatgtct tgaaacgctt tggtgtgcca gagtatgaat
     5041 tatctgcaat tactaagaaa atcagttttc gtgacaatct taagtcggcc tatgagggca
     5101 atctccagtt tcgtcagcaa atcaatagta agttagaata ccaaaaagct tttgagattg
     5161 cttgcaagat agagggctat ccaaggcaaa cctctgtcca tgcggctggt gttgtaatta
     5221 gtgaccaaga tttaaccaac tacattcctc taaagtatgg tgatgaaatt ccactgactc
     5281 agtatgatgc tcatggagtt gaggctagcg gacttttgaa gatggacttt ctgggactac
     5341 gaaatttgac ctttgtccag aagatgcaag agttgcttgc tgaaacagaa ggtattcatc
     5401 tgaaaattga agaaatcgat ttagaagaca aagaaacatt agctttattt gcctctggta
     5461 atacaaaagg tatctttcaa tttgagcaac caggtgccat tcgtctgctt aagcgtgtgc
     5521 aaccagtctg ttttgaagat gtcgtcgcga ctacttctct aaatcgaccg ggtgctagtg
     5581 actatatcaa taattttgtg gcaagaaagc atgggcagga agaagtgact gttctggatc
     5641 cagtactgga ggatattttg gctccaacct acggcataat gctctatcag gagcaggtta
     5701 tgcaggttgc ccagcgactt gccggattta gtcttgggaa agccgatatt ttgcgtcggg
     5761 ctatggggaa aaaggatgcc tctgccatgc atgagatgag ggcttccttt attcaaggtt
     5821 cattagaagc tggtcatact gtggaaaaag cagagcaggt ctttgatgtt atggagaagt
     5881 ttgcaggtta tggttttaac aggtcacacg cctatgccta ctcagccttg gccttccagt
     5941 tggcttattt caaaacgcat tatccagcca ttttttatca ggtcatgtta aattcttcca
     6001 acagtgatta cttaatagat gcacttgaag caggttttga agtagcctct ctatccatca
     6061 acaccattcc ctatcacgat aaaattgcca acaaggccat ctatctaggt ttgaaatcca
     6121 ttaaaggagt cagtaatgat ttagctctct ggattattga aaatagacct tattctaaca
     6181 ttgaagattt tatagctaaa ttacctgaga attatctgaa acttcctctg ctagaacctt
     6241 tggtaaaagt tggtcttttc gattcatttg aaaaaaatcg tcaaaaagta tttaataact
     6301 tagctaatct atttgaattt gtgaaagagt tgggaagttt gtttggagat gctatttata
     6361 gttggcagga atcggaagat tggacggaac aagaaaaatt ttatatggaa caagagcttt
     6421 tagggatagg tgtcagcaaa catccactac aagctattgc aagtaaggct atttacccga
     6481 ttaccccaat cggaaatttg tcagaaaata gctatgctat tatcttggtt gaagttcaga
     6541 aaataaaagt gattcgtacc aaaaagggtg aaaatatggc cttcttacag gcagatgata
     6601 gtaagaaaaa attggatgtt acactcttct cagatttata tcgacaggtt ggtcaggaag
     6661 taagagaagg agcattctac tatatcaaag ggaaagtcca atcacgtgac ggtcgtctgc
     6721 aaatgattgc acaagaaata agagaagcag ttgctgaacg cttttggata caggtgaaaa
     6781 atcatgaatc ggatcaagaa atttcacgta ttttagaaca atttaaaggc ccaatcccag
     6841 tcatcatccg gtatgaagag gaacagaaaa ccatcgtttc tccccatcat tttgtagcta
     6901 aatctgatga attagaggcg aaattgaatg aaatcgttat gaaaacgatt tatcgctaaa
     6961 aatacggaaa atagaagaat tttaaaatca aatgtgatat aatcaagaag aatgttaaaa
     7021 gaaaaaggag cataaccaat atgaaacgta ttgctgtttt gactagtggt ggagacgccc
     7081 ctggtatgaa cgctgccatc cgtgcagttg ttcgtcaagc aatttcagaa ggaatggaag
     7141 tgtttggtat ctatgacgga tatgctggta tggttgccgg tgaaattcat cccctagatg
     7201 cagcttcagt aggggacatc atttctcgtg gtggtacttt ccttcactca gctcgttacc
     7261 cagagttcgc tcaacttgaa gggcaactta aagggattga gcaattgaaa aaacacggaa
     7321 ttgaaggtgt agttgttatc ggtggtgacg gatcttacca cggcgctatg cgtttgactg
     7381 aacatggctt cccagctatt ggtcttccag gtacaatcga taacgatatc gttggtactg
     7441 actttacaat cggttttgac acagcggtta ctactgccat ggacgctatc gataagattc
     7501 gtgatacatc atcaagtcac cgtcgtactt ttgtaatcga agttatggga cgtaacgctg
     7561 gtgatatcgc tctttgggct ggtattgcaa ctggtgctga tgaaatcatc atccctgaag
     7621 caggcttcaa gatggaagat atcgtagcaa gcatcaaagc tggttatgaa tgtggtaaaa
     7681 aacacaatat catcgtctta gctgaaggtg tgatgtcagc ggctgaattt ggtcaaaaac
     7741 ttaaagaagc tggagataca agcgaccttc gtgtaacaga acttggacat attcaacgtg
     7801 gtggttctcc aactgcgcgt gaccgtgttt tggcgtcacg tatgggtgca catgctgtta
     7861 aacttcttaa agaaggtatc ggtggtgttg cggttggtat tcgtaacgaa aaaatggttg
     7921 aaaatccaat tcttggtact gcagaagaag gggcattgtt tagccttact gcagaaggta
     7981 agattgtggt taacaacccg cacaaagccg atattgagct atctagcttg aataagagct
     8041 tgtcataatt tacaatttag ttaataagac caaaaaggtc atatataaag gagtcacaaa
     8101 aatcatgaac aaacgtgtaa agatcgttgc aactttgggt cctgcggtag aaatccgtgg
     8161 tggtaaaaaa ttcggtgagg acggatactg gggtgaaaaa cttgatgttg aagcttcagc
     8221 taaaaacatt gctaaattga ttgaagctgg tgctaacaca ttccgattca acttctcaca
     8281 cggcgaccac caagaacaag gtgagcgtat ggcaactgtt aaacttgcgg aaaaaattgc
     8341 aggtaaaaaa gttggtttcc ttcttgatac aaaaggacct gaaatccgta cagaattgtt
     8401 cgaaggtgaa gctaaagaat attcatacaa aactggtgaa aaaattcgtg ttgcaactaa
     8461 acaaggaatc aaatcaactc gtgaagtgat tgcgttgaac gttgctggtg ctcttgatat
     8521 ctatgatgat gttgaagttg gtcgtcaagt tttggttgac gatggtaaac ttggtcttcg
     8581 tgtggttgct aaagatgatg caactcgtga atttgaagtt gaagttgaaa acgatggtat
     8641 catcgctaaa caaaaaggtg tgaacatccc taacactaaa attcctttcc cagctcttgc
     8701 tgaacgcgat aacgacgata tccgtttcgg tcttgaacaa ggtatcaact tcatcgcaat
     8761 ttcattcgta cgtactgcaa aagatgtgaa cgaagttcgt gcaatctgtg aagaaactgg
     8821 aaacggacat gttcaattat tcgctaaaat cgaaaaccaa caaggtatcg ataacttaga
     8881 cgaaatcatc gaagcagctg atggtattat gattgctcgt ggtgatatgg gtatcgaagt
     8941 accgttcgaa atggttccag tttatcaaaa aatgattatc aagaaagtca atgctgcagg
     9001 taaagttgtt atcactgcaa caaacatgct tgaaacaatg actgaaaaac cacgtgcaac
     9061 tcgttcagaa gtatcagacg tattcaacgc tgttatcgac ggaactgacg ctacaatgct
     9121 gtcaggcgag tctgcaaacg gtaaataccc actcgagtca gtaactacaa tggctacaat
     9181 cgacaagaat gctcaagctc ttcttaatga atacggacgt cttgattcag attcatttga
     9241 gcgtaactct aagacagaag taatggcttc tgctgttaaa gatgctacta gctcaatgga
     9301 tatcaaattg gtcgtaactc ttactaagac aggtcatact gcacgtttga tttctaaata
     9361 ccgtccaaat gctgacatct tagcattgac atttgacgaa ttgacagaac gtggcttgat
     9421 gttgaactgg ggtgttatcc caatgttgac agatgctcca tcttcaactg acgatatgtt
     9481 cgaaatcgct gaacgtaaag cggtagaagc aggtctcgtt gagtcaggcg atgatatcgt
     9541 tatcgttgct ggtgtgccag taggagaagc tgttcgcaca aacacaatgc gtatccgcac
     9601 agtacgttaa gaaaaatata aaaacctatc atatccagct ttagagcttg tgtgataggc
     9661 tttttgtata gagggtaaga aataggcaaa actttcataa tggattgata ctcttcgaaa
     9721 atcaaattca aaccacgtca gcgtcgcctt accgtatata tgttactgac ttcgtcagtt
     9781 ctatctacaa cctcaaagca gtgctttgag caacctgcgg ctagcttcct agtttgctct
     9841 ttgattttca ttgagtatga aataagatat gcacaaattg attaggaaat tcaaatgaat
     9901 ttctacaaat gttttagcaa tcgtaatgta cttgtctaga ttcgatctga tatattttcg
     9961 atttaatgat atggtattta aaacctccaa agtagcttgc tccattcttt tacttacgtg
    10021 agtgtagatg ttatttactg ttttagcgtt tttgtgttcc actctaacca ttatagcatt
    10081 cttctcagct agtgtactaa ggagtgtgtg cctgaaaata tgggaactaa ggggctggtt
    10141 tatcggtttc tctagtttag tatttgcctt ttgcaaagtg atgttaaatg cctttctcta
    10201 aatttacata tcactattgt ttaacaaaat ctaatctact ttaggtcact tattcttttt
    10261 ttgaaatgta gaatgaactt tttcaaagtt tttcgaatct tttaaaatct gtttgtttta
    10321 tatcgccatt ctcccccttt tttaattctc cctatatagc ctgacaactt tcccgatggt
    10381 acgaatatgg ttgctttcgt ctaggtggat gtcggggtat ttgggattga gtttttttaa
    10441 ggtagccttg gcggagtttc ttgacatagt tagcgccgtc tacttggaag atgccgatgg
    10501 tattatagtc aatctgtggg gtattcttga taaataggta gtcgctgttt cttatctttg
    10561 gctccatgga cttgctgacg acataagcga ttgggtcgta gtcgtctggg ataatggaaa
    10621 ctccataact aaatcgtcgt cctgcatcga gcggctacct gcagagataa actacctaac
    10681 acgagagtaa gtagtctgtc tgtagtcgtc cagtctgatg atttttacga tatttcgttt
    10741 ttctgctcat acagttgcct ctcggcatag gtcagaactt taccttgtct gggtggtgcc
    10801 cgttggtcgt agatagattg gatatcgcta ggagaatcct tttgaactgg aggaaagagg
    10861 gtatcaatca agctactgaa tactttagct aagtcaaata tagtattttt cttagtagac
    10921 ctaacccttt tttcataatt tccaatggtg tttttactta taccaatctt agtacccaat
    10981 tcttattgag tccaaccatt actagtctat attgttttat agttgattga gtttggaata
    11041 gtacgctgta gctgctaaaa catttctagg aattaatttg actttcctaa tagagttgtt
    11101 catatcttat ttcaatctac tatgtttttc acctctaaca atcgcaatct cttctttatc
    11161 catgaatgaa atcgctttct atttttgtaa gtaaagcatc acacgaaatc cacgaaaatg
    11221 aaaacctttg ttgtgttttc gtaaaaaatt tgttgacaga gcacgaaacg cctactataa
    11281 ttaaatcaag cttaaggaaa taacaaaaaa acaaatcgga gggaaagacg atgaacacat
    11341 taaatgagaa agtaatcaat atctgtaaag cagtagttaa agaaacttta atccaagaca
    11401 tttaggagaa agaaatgaag aaatcaagaa aattagccac attaggaatc tgttcagcct
    11461 tgtttttagg cttggctgct tgtcaacaac aacatgctac ttctgagggg acgaatcaaa
    11521 ggcaaagcag ttcagcgaaa gttccatgga aagcttcata caccaaccta aacaaccagg
    11581 taagtacaga agaggtcaaa tctctcttat cagctcactt ggatccaaat agtgttgatg
    11641 cattttttaa tctcgttaat gactataata ccattgtcgg ctcaactggc ttatcaggag
    11701 atttcacttc ctttactcac accgaatacg atgttgagaa aatcagtcat ctctggaatc
    11761 aaaagaaggg cgatttcgtt gggaccaact gccgtatcaa tagttattgt cttttgaaaa
    11821 attcagtcac cattccaaag cttgaaaaga atgaccaatt gcttttccta gataacgatg
    11881 cgattgataa aggaaaggtc tttgattcac aagataagga agagtttgat attctatttt
    11941 cgagagttcc aactgaggca actacagatg tcaaggttca cgctgaaaag atggaaacat
    12001 tcttctcaca atttcaattc aatgaaaaag ctcgaatgct gtctgtagtc ttgcacgaca
    12061 atctggatgg cgagtatctg tttgtaggcc atgttggggt cttagtacct gctgatgacg
    12121 gtttcttatt tgtagagaaa ttgactttcg aagagcccta ccaagcgatt aaatttgcta
    12181 gtaaggaaga ttgctacaag tatttgggca ccaagtatgc ggattataca ggcgagggac
    12241 tggctaagcc ttttatcatg gataatgata agtgggttaa actttaatag tgttatgata
    12301 tgacagtaat cttaggattt ttatttctat ttttgatgac ttggtgggtt atttcaatcg
    12361 ttaatagcca gaaaccacgc aaaaatgaaa catttattgg ctatatccaa agatacgata
    12421 ttgatgggaa tggctatcaa tcattaccgt gtcctcagaa ctgagaggag ttcttgaaac
    12481 cgtaaaaccg ctttgaacaa gagttacttc aacccattgg ctccgacgga gtaagttgct
    12541 ttcgtgaata ccaaaatcag ccgcaatttg ttcataagtt cgatattctc gcacatattg
    12601 aagagtggcc ataagaaggt cttctaggct taatttaggt tttcgtccac cttttgcgtg
    12661 tttaagttga taagctgttt ttaatacagc taacatctct tcaaaagtgg tacgctgaac
    12721 accaacaaga cgcttaaatc gtgcatcagt tagttgttta cttgcttcat aattcataga
    12781 actactatac catattttgt ttcgcaggaa gtctaatgct aaaatcttat cagtgagaag
    12841 atttcttaaa gtttattctt tgtagtttca tctgtattag tacataattt aacttagaga
    12901 aaataggagg actaatcgaa tggaattaaa agattttaca gaaaaagaac aggaaatgat
    12961 taagaaaagg cttacaatgt ctaatattag tgacaaagaa actactgaga agattctggc
    13021 gctagtccca caagacttga ttaagcgaat cccgtttttt gtcagaaaac atgctacaac
    13081 acgtacgatt aaacgtattt caattgaata ccctgaactc tacgctgtag ctcaaacaag
    13141 tggtgagatt ccagaaaaaa acgcgaagaa ttgcgtcaga ttatcacaac tatctttgaa
    13201 caaaagatga ataagcatag tattaagtag agaatgaaaa aatattttat tggcggtttg
    13261 ggaagcaatg cctatcatag caaggatttt cttcaagaac tagattcgca ggtctatttt
    13321 ctaaatccat atgaaaagca tcttcgagat gaaacagaat tgaaatcatg gtttaaaaat
    13381 gagattgtag aggaagaatc tatctgtctg ataggtcatt ctattggagg cgatttagct
    13441 cgttatttcg catcggaatt tgaagaagta aagaaactga ttcttttgga tggtggctat
    13501 ctagatttag ataagatttt acctttggat acagagttag aggaaactaa aaattatatc
    13561 aaatctcaaa ttatttcgga cttagatgtt cttacttcta aagaaaaatc tgaagcaaag
    13621 cattggtcag aaaatatgga gaaagctgta agacagtcct atcactggaa tgttgagtat
    13681 aatagatatg agttggctat aaattatgaa aatatagaag cgatactccg cctacggaga
    13741 aaaatacaag cttttaagag agaagtggga gataccttgt ttattagtcc tcgctatcct
    13801 aatgaagcta catggagaga ggaagcccta aaagaattgc cagactattt tgatactatt
    13861 tttttagaaa actttggcca tgagctttat actcaagcac ctaaagaaat cgctagtcta
    13921 atgaatgagt ggctcgctta ttttctatga gctacttgta ttgctggaaa tggtataaga
    13981 tgaaaatcta caagtcacta attttcatat aacaaaaaac gaacaggctc tttttctgtt
    14041 attcagaaga gaacttgttc gtttttatct tgattttctt aaaaagctct atatacatag
    14101 ggattttctg gtttatcgac tttggtaaag ctgtcgattt ccaaggttgg aaggttttgt
    14161 ttgagttctt tatggtagtg attgaccagt tttcctttgg ctgttatcca agtgttgttt
    14221 tcatactgcc gggtattgcc cttggtcagc aatccataga caccagaatc tgcgatacag
    14281 tggataatgc cgaatcggaa cagaaattga ctattggcat gactggggtc gttatagaca
    14341 aagcctgtaa actggattgt cttgccctca aactcatctg gatagtcgta gatagcctcc
    14401 atgacttcca tatagttttc attagtgatc tgaatactat cttgggataa gtatttatcc
    14461 gccgccgttc gcatttcctt ttcataggct gattttgaaa aataagaact ggtatctggt
    14521 ttcaaatatt ggcttgtcgt cccttcgctt gtctgaatgg ctagatctgt tccttccgat
    14581 agggggaaat gataaccttt agcagaaacg gtctgagaat ccaagctaac agttgggaaa
    14641 gttaagccga tgacaagtgg aatagccaga agagaaatac tcgtcatctt ggccaatcgg
    14701 ctgttcagat gactgtgggt tttgacttgc ttcatccaga tatacaattg aacaattgcc
    14761 aagataaagg aaagcaccat ggagatatag gccagatagg aatagtgcat gttgatgtac
    14821 tggtttagtt tgcccgacag atggaggtaa atagtcagtt caaaatagcc agctaaaact
    14881 aaaaatcgaa tcataggatg actccaatca agagagaata gactaagacg acaagagtta
    14941 caatcgttat gaagtgactg ataaatcgtg ctttcaagta atttttcatc atgagaatat
    15001 ttttgatatc cagcattgga ccaatgacga gaaaggccag aactggtgcc aaaccgaaac
    15061 tcgagagaag agaagcacct ataaaggcat ccgcctcact acagagcgaa agaagaaagg
    15121 ccaaaatcat caagagcagg atggcaaaaa gaggagtcgc actgatagag gtcagaatcc
    15181 gagtcggaac gtagacctgt attatagaag caaagaggca gccaaatacc aaataacgcc
    15241 ccgtatcaaa aaattcatca atggcctgca caaagacttg aaaaactttt tttgcagaac
    15301 tcaagtaaga aaaatcatgc tcatgacaag ccagacgatt ttctttctga atcggttctt
    15361 gccagaaaaa tcctagaaaa attcctagta ttacagccac aagaatggaa cccagagctc
    15421 gtaatagggc gacatggaag gagttgccaa aggcagaata ggtcgcaaaa agaacaatgg
    15481 gattgataac aggtgctgtc acaagaaaag gaacggctgt gtaactggga accttttttt
    15541 ccagaaaacg attgatgatg gggacgattc cacattcaca agaagggaaa agcataccga
    15601 caaaggtccc aaaaaagatt ctcccccaac gatttcgagg gagaaaatga taaaccttgt
    15661 caggtgtgat ataaacttca atcagccctg agacaatgct tcctattaga acgaagggaa
    15721 gggcttcaat gataatggag agaaaaatgg ctccagtttg aagtacacta gatgggagtt
    15781 gttgaaaagc agtcatctag tttttctttt ctgctttggc ttttttctct ttgtcatcag
    15841 ggaaagtaac ttgtttcaaa tcagggagtt tagcaaactc ttcaaacatc ttgtccaagt
    15901 cgtctcgttt tgtaaatttt acagccatag gtgtacctcg attctaaagt ctacctctat
    15961 tatactatta ttttgcggaa aagggagttt tttaatttgt tttcgatagt tgatacactt
    16021 cgaaaatctc ttcaaaccac gtcagcttcg ccttaccgta tatatgtgac ttatccacaa
    16081 cctcaaaaca gtattttgag cagcctgcgg ctagcttcct agtttgcttt ttgattttca
    16141 ttgagtatga aaaggattgg agaaagcctt ccagcttgtg gtataataga tttatggata
    16201 aaaaatatga aaaaatctct caggatttgg gagtgatgtt aaagcaaatt gataccgttc
    16261 taagtttgac agctgaaggg gcgactattc cctttatcgc gcgttatcgc aaggacatga
    16321 ctggtagtct ggatgaggtg gcgattaagg ctattattga tttggataaa agtctgacaa
    16381 atctcaatga ccgtaaggaa gctgtcttag ctaagattca agaacaaggt aagttgacca
    16441 aggaattgga agaagctatc ttagttgccg aaaaattagc agacgttgaa gaactctatc
    16501 ttccttataa ggaaaagcgt cgtaccaagg caaccattgc ccgtgaagct ggactctttc
    16561 ctcttgctcg tttgattttg cagaatatag ttgacttaga gaaagaagct gaaaagttcg
    16621 tctgtgaagg atttgcgact ggcaaggaag ccttgaccgg tgcagttgat attttggtcg
    16681 aagccttatc ggaagatgtg accttgcgtt ctatgactta tcaggaagtg ctgagacact
    16741 ctaaacttac ttctcaagcc aaggatgaaa gtcttgatga aaagcaggtt tttcagattt
    16801 attatgattt ttcagagaca gttggaacta tgcaaggcta tcgtaccttg gctctcaatc
    16861 gtggggagaa acttggtgtc ttgaagatcg gttttgaaca tgcgacggac cgtattcttg
    16921 ccttctttgc tactcgtttc aaggtgaaaa atgcttatat tgatgaagtt gttcagcaat
    16981 ccgttaagaa aaaggtcttg cctgctatcg agcgtcgtat tcggacagaa ttaactgaga
    17041 aagctgaaga aggagctatc caactttttt ctgacaatct gcgcaatctc ctcttggttg
    17101 ctccactgaa agggcgcgtg gttcttggat ttgacccagc ctttcgtaca ggtgccaagt
    17161 tagctgtcgt ggatgcaaca ggaaaaatgc tgacaactca ggttatttat cctgttaaac
    17221 cagcatcagc tcgtcaaatc gaagaagcca agaaagattt agcagattta attggtcaat
    17281 acggtgtaga gattattgcc attggaaatg gaacggccag tcgtgaaagt gaagcttttg
    17341 tagcggaagt tctgaaagat ttccctgaag tcagctatgt tatcgttaat gaaagtggtg
    17401 cttctgtcta ttctgccagc gaacttgctc gtcaggagtt tccagacttg accgttgaaa
    17461 aacgctctgc catttctatc gcccgtcgtt tgcaagatcc tcttgcggaa ttggtcaaaa
    17521 tcgatcctaa gtcaattggt gtcggtcaat accaacacga tgtcagtcag aagaaactat
    17581 ctgagagtct ggactttgtt gtcgatacag tggttaacca agttggtgtc aatgtcaata
    17641 cagctagccc agctcttctt tcacacgtag ctggactcaa caaaactatc tctgaaaata
    17701 ttgtcaaata ccgcgaggaa gaaggaaaaa tcacttcacg cgcccaaatc aagaaagttc
    17761 ctcgtctggg agccaaggcc tttgagcagg ctgctggttt ccttcgtatc cctgaaagta
    17821 gcaatatcct tgataataca ggagttcacc cagagaatta cactgcagtt aaggaactct
    17881 tcaaacgttt agatattaaa gacctaaacg aagaagccca aagcaaactc aagtcccttt
    17941 cagtcaagga aatggctcaa gagctagacc tcggtccaga aacccttaaa gatatcattg
    18001 cagatcttct caaaccaggt cgagatttcc gtgattcctt tgacgcacct gtgcttcgcc
    18061 aagatgtcct agatatcaaa gacctagtgg taggtcagaa gctagaaggt gttgtgcgta
    18121 acgttgttga cttcggtgcc ttcgttgata tcgggattca cgaggacggc ttgattcata
    18181 tttctcatat gagtcgcaag tttatcaaac accctagtca agtggtgtca gttggagatt
    18241 tggtgaccgt ttgggtcaag aaaattgata ctgaacgtga aaaagttaat ctgtcgctcc
    18301 tcgctccaaa tgaaactgac tgattatgtc aagcaggttt cactagaaga cttcgggaga
    18361 gcttttatcc atcatgtcca gtggaatagg cgtctacgtt cgacaggtgg gcgatttttc
    18421 cccaaagatg ggcatctgga ttttaatccc aaggtttatc agaaactggg tatggaggtt
    18481 tttaggaaaa ttgtccgaca tgaactctgt cattatcacc tttatttcca agggaagggc
    18541 tatcaacaca aggatcggga ttttaaggaa ctgttgaaag cagtggatgg attaaggttt
    18601 gtaccatcct tgcccaatag taactctaaa ccactcaagc tttatcgttg tcaatcctgc
    18661 cagcaaaggt atcagcgcaa gcgtaggatt gataccaaac gctatcgctg tggactttgt
    18721 cgaggtaaat tgcttctgat aaatcagcct gaggactgat gaaagccgag cctccccgtg
    18781 atatactatg tctaacctag cagaaagagg aaatatcatg aacagtaaat tttataaaat
    18841 gagacgcaat cgcatgattt caggagttct ggcaggtctg tcagacaagt ggaattttga
    18901 tgttacccta gttcgtttct tgtttgccat ttttacagtt gcaaactttg gacttggcgt
    18961 gattatctat atcatcctag cttctatcat gcctaccaag gaagaaatcg aagcagaaat
    19021 gtacggaaca ggcccacgta aacgcaaaga agcccaagcc attgacgaca atgaaggctg
    19081 gttttggtga ggttctacag aagatttgga ataagcaaaa agctttaaat caatagtcta
    19141 aactgcttga tttaaagctt ttttactttt atactcaata aaaatcaaag tgcaaactag
    19201 gaagccagcc acaggctgta atttagtcgg caatgtgaag ttgacatagt ttgcactttg
    19261 atttttgaat agtattaata atatttcgcc agcttcatcc acaaactata gtggattgga
    19321 actagaatag tacacctcta cttctaaaac attgttagaa atcgatttga ctatcctgat
    19381 cgatttgtcc tgttcttatt tcattttatt ataaaagcag taatttaaac tcagtttttt
    19441 aatctatttt tgctgctgag acaatacatt tttggaaaaa tggtggatgc tgataacaac
    19501 tgataaccag caaataacat aagcagtgcc ggtaaattct gtaccgataa agtgtgtgtg
    19561 ttcaactaag agctgaccga tgaatggaga gagcagatag agaagtccga tgagtatatg
    19621 ttctttgtgt ttcattaaag cgcaccttct ttccttatag gttgaacgac ttgcaagtgt
    19681 taaattgaat ggtatgttat ctaggtaagc ttactcaaat gatagttccc gcttcctcct
    19741 ttccaaagta agccttttca tacttatatt ttacaacttt aaaaatagga aatcaaatca
    19801 ttttctaagt aattttgctt atatttcacc caatcttaca aaaatgtaag attaaagtct
    19861 cttttgtaag gttaggttat ggcaagcggt ctttttttga tgtaaactag actcataaag
    19921 aacaaaggag taacatcatg aaacaaatct tacataagaa aactagaaaa ccaagtcaca
    19981 aagaaattga gcgcgttcag ctgggatgca ctatgatgca agctacattt catttgatgg
    20041 gatattaaga aaggagattc tcatgacact tttagatgta aaacacgttc aaaaaattta
    20101 taaaacacgt tttcagggca accaagtaga agccctcaag gatattcact ttaccgtcga
    20161 aaagggtgac tacgttgcca tcatgggtga gtctggttct ggtaaatcaa ctcttctcaa
    20221 tattctagct atgctggata aaccaagtcg tggtcaggtt tacttgaatg gaactgacac
    20281 cgcaaccatt aaaaattcac aggcctctag cttccgtcgt gaaaagttgg gctttgtctt
    20341 ccaagacttt aacttgctag atactctatc tgtaaaggac aatatcttgc ttccgcttgt
    20401 cttgtcaaga agacctatta cagagatgat gaagaaattg gtggtgacag ctgagaatct
    20461 gggaataaac caattacaag agaagtaccc ttacgagatt tctggtggcc agaaacagcg
    20521 tgtagcagta gcacgcgcca tcatcactga acctgaaatt ctccttgcgg acgaaccgac
    20581 aggagctctt gactccaagt catctgcagc cttacttgat gtctttgatg aaatcaatga
    20641 gcgcggccaa accattctca tggtaaccca ctcaacagca gcagctagca gagctaaacg
    20701 tgtactcttt atcaaagacg gcattcttta caatcaaatc taccgtggag agaagacaga
    20761 acgtcagatg ttccaagaaa tctctgatac cttgactgtc atggcaagcg aggtgaatta
    20821 gtatgtttcg attaaccaat aagttagcgg tatcgaactt gattaaaaac cgcaaactct
    20881 actatccttt tgcgctggct gttctcttgg cagtcactgt cacctatctc ttttactctc
    20941 taaccttcaa tcccaagatt gctgaaattc gtggaggaac aaccattcag gctacacttg
    21001 gatttggtat gtttgtcgtc acccttgcgt cagccattat cgttctctat gccaatagtt
    21061 ttgtcatgaa gaaccgttcc aaggaactag gaatttatgg catgttgggc ttggagaagc
    21121 gtcatcttat cagtatgacc tttaaggagt tagtggtatt tgggattcta actgttggag
    21181 cgggtatcgg tattggagcc ttgtttgaca agttaatttt cgctttcctg ctcaaactaa
    21241 tgaaattgaa ggttgagctg gttgctacct tccagacgaa agttgtcatt acagtgcttg
    21301 ttgtcttcgg tttgattttc ctaggcctca tgttcctgaa tgcccttcga atcgcccgta
    21361 tgaatgccct ccagctctct cgtgagaaag ctagtggaga gaaaaaaggt cgcttccttc
    21421 ctctccaaac cattcttggt tccataagtt taggaattgg ctattatctt gcccttacgg
    21481 taaaagatcc tcttacagcc ttaacaacct tcttcatagc tgttttactg gttatctttg
    21541 ggacttatct cttgtttaat gcagggatta ccgttttcct ccaaatctta aagaaaaata
    21601 agaaatacta ttaccaacca aataatctca tatctgtttc taacttgatt ttccgtatga
    21661 agaaaaatgc agttggacta gccaccatcg ctatcttgtc aacaatggtt ttggtaacca
    21721 tgtcagcagc gacaagcatt ttcaattcct cagaaagctt taaaaaagtt ctaaatcctc
    21781 atgattttgg ggtttcaggg caaaatgttg aaaaagaaga cttggacaaa ctcttgagcc
    21841 agtttgcaag tgacaaaggt tatagtgtca aagagaaaga agtacttcgt tacagtaact
    21901 ttggtattgc aaatcaagaa ggaactaagt taactatttt tgaaaaagga caaaaccgtg
    21961 tccaaccaaa aacagttttc atggtatttg accaaaaaga ttatgaaaat atgactggtc
    22021 aaaaactgtc tctatcagga aatgaggtcg gactctttgc aaagaatgag ggagttaaag
    22081 aacagaaagc tctaactcta aatgatcatc aattttctgt aaaagaagaa tttactaaag
    22141 attttattgt caaccatgtt ccaaatcagt ttaatatttt gactgctgat tacaattacc
    22201 ttgttgtacc tgatttacaa gcctttttgg atcaattccc agattcggct atctataatc
    22261 agttttacgg tggtatgaat gtaaatgcca gtgaagcaga acaactcaag gtcgctgagg
    22321 agtatgaaaa atacttacaa aagtttaatg ctcaattaaa cactgaaggt aactatgtgt
    22381 atggtagcac tctagcagat gctagtgctc agatgagtgc cctctttggt ggtgtcttct
    22441 ttatcggtat tttcttatcc attatcttta tggtcggaac cgttctggtc atctactaca
    22501 aacaaatttc tgaaggatat gaagaccgtg agcgctttat tatcttgcag aaagtcggtt
    22561 tagatcaaaa gcaaatcaag caaaccatca acaaacaggt tttaactgta ttcttccttc
    22621 ctttgctctt tgccttccta catctagcct ttgcctacca tatgcttagt ctgattttaa
    22681 aagtgattgg tgtactggat acgactatga tgttgattgt gaccttgtct atctgcgcta
    22741 tcttcctcat cgcctatgtg ctgattttca tgattacttc aagaagttat cgcaagattg
    22801 tgcaaatgta aaaaagatac ctcgacttca aaatcgaggt atttcttgta ttctaaatgc
    22861 tgaaaagttg ttcgagcagg aaggtaactc ccatggtcaa gagaccaata gcaaggttcc
    22921 gaatcatagc tgttttggtt ggggcttttc caagtctagc acttgtgtaa ccagtgagaa
    22981 gaagggccac accgacaata aggacggtag cagggatgcg gtaatcactt ggaaaaatgg
    23041 tcactgacag cattggaggc aaacttctaa ggaaaaaggc aacgaagcta gaaatggcag
    23101 cgtgccaagg attggtaaat tcttcatact caatcccata tttttcctct accagagcct
    23161 tgagtggatt tttaagaaag atcttattag tcaagagttg ggcagaagtt ttgaattctt
    23221 cattttggat ataagcagca tagagggatt ttttggctag ttccctatct tggtctagca
    23281 agagtttttc tcgcgaaacg gcagcttcct cggtatcttt tggagttgaa acggatacat
    23341 attctccacc agccattgaa aaggcaccag ctaagatagc cgcaaatcct gataaaaaga
    23401 taatccagat attggtcgtg gcactggcaa ccccgataac cacaccagca atggaaataa
    23461 ttccatcgtt agcatcaaga acacccgcac gcaggatatt taaacgacct gcaaaatttg
    23521 aatcaatttc gtgatttgtt tctgacgcta aatttcaagt tcaagttagc catcca
//
LOCUS       DAVBIC010000036        23312 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.036, whole genome shotgun sequence.
ACCESSION   DAVBIC010000036 DAVBIC010000000
VERSION     DAVBIC010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23312)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23312)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23312
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.036"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            complement(196..654)
                     /locus_tag="VQ664_001403"
     CDS             complement(196..654)
                     /locus_tag="VQ664_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HET2789556.1"
                     /translation="MKKQVFHDAAAGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWAAIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(651..1091)
                     /locus_tag="VQ664_001404"
     CDS             complement(651..1091)
                     /locus_tag="VQ664_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2789557.1"
                     /translation="MKVELQISETYEEEKLIVQAPQPTDKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPTNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            1675..2541
                     /locus_tag="VQ664_001405"
     CDS             1675..2541
                     /locus_tag="VQ664_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2789558.1"
                     /translation="MGTLLATRLKNRRKELKMSQRELAEGICKQGQISRLESGEFTPG
                     ADFLHALAKKLKVSMDYFFDEQVVEKVEELSEFKKLAQTFITNRNYESLKYIYELENV
                     KAHRLSLADKIYMEWIKSLIDFYFYGQKEDAIVRLEGVLSQLSVSDLNYLQVSNTLFN
                     FYYDIGDLGRFNKIREKLEYQVNHLNLSTIEELELSIKFNYNVCRYLWLQKNIEEAIT
                     KITATIKQCKAYRTNYLLADLYLLMGNVSENFSSKSSVKEYFETAYFLYKLEENMSMT
                     LKVEHYIADITE"
     gene            2878..3435
                     /locus_tag="VQ664_001406"
     CDS             2878..3435
                     /locus_tag="VQ664_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase family
                     flavoprotein"
                     /protein_id="HET2789559.1"
                     /translation="MDKKNLLVLVTGSVGASNVDTYLYYIKKFYNVKVILSENSKKFI
                     SKELISYFCDKVYDEIFVEEVVPHVFLPYESDLLLILPATANVIGKIANGIADDLVTA
                     TVLNFNKKIIFCPNMNSTMWDNHIVQRNVSILKELGHIFLFESKKTYEVGLRKAIDST
                     CSMLQPQSLVKELIKLENIVLEEGH"
     gene            3656..4762
                     /locus_tag="VQ664_001407"
     CDS             3656..4762
                     /locus_tag="VQ664_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal-dependent decarboxylase"
                     /protein_id="HET2789560.1"
                     /translation="MINKKIQQVVLESLQNFLNGNFISPCVVYDFGLLETVLDEFKNQ
                     IPVTFNYQLFYAVKANSNEKILEFLVDKIDGVDVASLSELDVAKKFFPPTQISVNGPA
                     FSYETLYNLIKKQYKVDINFLEHLQQFSPKESVGIRVTEPDELNNRMSRFGINICSDN
                     WTSNLQNPLITRLHFHFGEKDDKFIVKLDKILFKLQEINKLREVREINLGGGFMKLFM
                     ENRLKEFFLSLMEIYKKYDIDSTVTTIIEPGSAITSFSAYMITSPVNVSEVNEQQVIT
                     LDTSIYTNTLWFVPHIITTLNSSSKERYSTILYGNTCYEHDKYKMKVSLPRLTQNSSI
                     VFFPVGAYIKSNHSNLHRNDFMREVYLWTKNLTY"
     gene            4738..6129
                     /locus_tag="VQ664_001408"
     CDS             4738..6129
                     /locus_tag="VQ664_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789561.1"
                     /translation="MDKKLDILDKVKEYLGNKTTQILDNQYKEFLKLNDIRRAFGISE
                     KVLNNSFNFTSKEFNDLINNENYLFEYACRIREEWRKKCFNHSYRFLCSPIITDDFLN
                     TKTLRSSQIEYKYERYLSKSSIGDRAVDGFVSFNTLTANGMSAIKLCLEILNSIFFKK
                     KIDLLYSTGYYETRFLLNNLAKSGISCYEVSNCELDKDKFYNVFMMEPNRADLTLQKT
                     DFKIVEYFVKYKNNSIKVVILDISYQGSNFKLVEFLEKFKFANVIIFVVRSLIKLDQM
                     GLELTNGGIIEVFIPNHLRKLKNFIEEEFNKFRNSHGANLSLYEYCLLDNSLTLKNDW
                     NYSDLVMKFTSNFYADIKDLFMENSDIEIIHEEGVPFVFLDLIGEGKKEYEMFFQWLN
                     FFYKQLGITLYARNSFGFRNLTVEYFGIIGTERYIFKICPGVYKGLSYYLMKFLLKSF
                     SNEYLKTTDEVNR"
     gene            6126..7304
                     /locus_tag="VQ664_001409"
     CDS             6126..7304
                     /locus_tag="VQ664_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET2789562.1"
                     /translation="MKNLIKLLIIRLIVNLADSVFYIVALWHVSNNYSSSMFLGIFIA
                     VNYLPDLLLIFFGPVIDRVNPQKILIISILVQLAVAVIFLLLLNQISFWVIMSLVFIS
                     VMASSISYVIEDVLIPQVVEYDKIVFANSLFSISYKVLDSIFNSFASFLQVAVGFILL
                     VKIDIGIFLLALFILLLLKFRTSNANIENFSFKYYKREVLQGTKFILNNKLLFKTSIS
                     LTLINFFYSFQTVVVPIFSIRYFDGPIFYGIFLTIAGLGGILGNMLAPIVIKYLKSNQ
                     IVGVFLFLNGSSWLVAIVIKDYTLSLILFFVCFMSKGVFNIIFNSLYQQIPPHQLLGR
                     VNTTIDSIISFGMPIGSLVAGTLIDLNIELVLIAISIPYFLFSYIFYTDNGLKEFSIY
                     "
     gene            7729..7962
                     /locus_tag="VQ664_001410"
     CDS             7729..7962
                     /locus_tag="VQ664_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000623387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET2789563.1"
                     /translation="MISIDLGGTNIKITVLSNDGEIETLWSITTDTSEKGSQIISDII
                     SSIKNKLTERNIPDSDLLGIGMGSCSSYFPCKS"
     gene            8245..10194
                     /gene="mutL"
                     /locus_tag="VQ664_001411"
     CDS             8245..10194
                     /gene="mutL"
                     /locus_tag="VQ664_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HET2789564.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKIQITDNGYGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVEQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(10519..10986)
                     /locus_tag="VQ664_001412"
     CDS             complement(10519..10986)
                     /locus_tag="VQ664_001412"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HET2789565.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWVPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(10987..12192)
                     /locus_tag="VQ664_001413"
     CDS             complement(10987..12192)
                     /locus_tag="VQ664_001413"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HET2789566.1"
                     /translation="MEYRKIQEALEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERNGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLVERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(12212..12847)
                     /gene="ribE"
                     /locus_tag="VQ664_001414"
     CDS             complement(12212..12847)
                     /gene="ribE"
                     /locus_tag="VQ664_001414"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HET2789567.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSVNGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLEQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(12832..13932)
                     /gene="ribD"
                     /locus_tag="VQ664_001415"
     CDS             complement(12832..13932)
                     /gene="ribD"
                     /locus_tag="VQ664_001415"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HET2789568.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAVIVKDNHIIGQGYHE
                     FFGGPHAERNALKNCRESPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVHQLRHHVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(14067..14181)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            14338..14931
                     /gene="ruvA"
                     /locus_tag="VQ664_001416"
     CDS             14338..14931
                     /gene="ruvA"
                     /locus_tag="VQ664_001416"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HET2789569.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQEA
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDGLPAKVAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            14941..15504
                     /locus_tag="VQ664_001417"
     CDS             14941..15504
                     /locus_tag="VQ664_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HET2789570.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWGQPLHDDQALFELLCMETYQA
                     GLSWETVLNKRQAFREAFHSYQIHSVAEMTDTELEAMLENPAIIRNRAKIFATRANAQ
                     AFLQLQAEYGSFDAYLWSFVEGKTVVNDVPDYRQAPAKTPLSEKLAKDLKKRDFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWKGLK"
     gene            15501..16178
                     /locus_tag="VQ664_001418"
     CDS             15501..16178
                     /locus_tag="VQ664_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2789571.1"
                     /translation="MMSNKNKGILIFAILYTVLFVFDGVKLLASLMPSAIANYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVGL
                     VGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLPGLLSIILV
                     GLVFALTHMHSLALSEWIGAVGYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(16319..17350)
                     /locus_tag="VQ664_001419"
     CDS             complement(16319..17350)
                     /locus_tag="VQ664_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HET2789572.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKDLGLNPIFLPHS
                     LKGLDFIKDHPEARAEDLIHAFSDDSIDMILCAIGGDDTYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIETGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGRALFEGKILGGCLESLYDIFD
                     NSRYADSTELCQKYKLFPDLSDWEGKILLLETSEEKPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDSNIPIVYNLNAGHATPRAIVPFGVHAHVDAQE
                     QVIRFDYNK"
     gene            complement(17605..18288)
                     /locus_tag="VQ664_001420"
     CDS             complement(17605..18288)
                     /locus_tag="VQ664_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HET2789573.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGPDMDRSQRPPFWK
                     SVLVILASVFLWLLVFFATSFLPASLNPVLDPLPLAIIGAALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(18300..19244)
                     /locus_tag="VQ664_001421"
     CDS             complement(18300..19244)
                     /locus_tag="VQ664_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HET2789574.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            19376..22207
                     /gene="uvrA"
                     /locus_tag="VQ664_001422"
     CDS             19376..22207
                     /gene="uvrA"
                     /locus_tag="VQ664_001422"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HET2789575.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAIKASSVEQIVDKVLELPERQRLQILSPVIRKKK
                     GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDNSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPNASKTLHEGALAPWNPISSNYYPNMLEQAMTAFGVAMDKP
                     FEDLSEEDKNLILYGSDGKKFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCHGYRLNDQALSVRVGGEQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVIGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDDGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            22200..23261
                     /locus_tag="VQ664_001423"
     CDS             22200..23261
                     /locus_tag="VQ664_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HET2789576.1"
                     /translation="MNKRVQAFLAKMQEKELDGVIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMGLTRIGFEDEISVSYY
                     HRMQAAFAGLNLLPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
BASE COUNT         7035 a         4105 c         4754 g         7418 t
ORIGIN      
        1 agatctgaaa taactgttat gatatagagg attgaaacta gaatagtaca cctctgcttc
       61 taaaacattg ttagaaatcg atttgactgt cctgatcgat ttatcctgtt cttatttcat
      121 ttcactatag taaggtgcag caggataaag aaaaaccgag aagtttcttt ctcggatttg
      181 cttattatga ggttcctatt ttctatgctc caagagttga ttgatgtgat ctactttttt
      241 agcctctctt ttatagagaa tagcccagat gatgagatag acaatcgcaa actcgataat
      301 gagctggagg tagaaaatcc agtggaaagg gaaccaacca gcaagagttg ctagtgggac
      361 aaagccagcc agcataagga agaaatgagt cagagtggca cgaagcatgc tccagtcacg
      421 gctgaataag cgattgccaa agttgaagag cataccaatg gctgcccaga taagtgtgca
      481 gtagagcaag accaaggcac cgtgaacctg atgctgatcc atcacttggc cgatgagaga
      541 gtagggattt agtggtgcgt aggtatttgg tgcataaatg agtgaaaaga ggatagagag
      601 gatgaggccg ataagaacac cggcagctgc atcgtgaaat acttgttttt tcatagttct
      661 aatttctcct tgatggtttt tagataacgg cgtgaagagt aggtgaagct ttcgtttttc
      721 aagaaaattt ctaccagacc gtttggcgtg agcttgaggt gagagatgga atcgatattg
      781 atgatttctg attgggaaat ttggataaaa ttggttggca agagtttaag aacctgatag
      841 agtcgcaaat caatgctgta ggtctgactc gcggtttctg ctagaacctt ccgattctcg
      901 atatagaagc gctgaatctt gccaatctca actagataga cctgatcatc gattttccct
      961 ttgatttttt ctctttggtc cagattttct gcgaactcga tgactttctg aactttatct
     1021 gtcggctgag gtgcttggac aatcagcttt tcctcctcgt aagtctcact aatctgtaat
     1081 tctactttca taaatttctc tccttgtttt tcatacaaaa ttaatctcac ttcttgtaca
     1141 cctttattaa tactcttcaa aaatctcttc aaaccacgtc agcgtcgtct tgccgtagga
     1201 tagttgttga ctttgtcagt tttatctaca acctcaaaac agtgttttga gctgtctgcg
     1261 cctagctttc tagtttgctc tttgattttt attgagtata ccactatttt actccctctg
     1321 gcaaggtact ttgtctatgt ggagggattg ggctcctatg tggtggagct tttctgttct
     1381 ttctgaaata tggtataata gcactaatca atttctagga aaatagatac agaaaggggc
     1441 tgaaagaact aggggaacag ttgtaattag aaggtgatag gtatgaaaag tggcgttgaa
     1501 gctggataag tttataaaga gtttgaatga agaaatgaaa agtaaataag ttgatgatga
     1561 attgcaaaaa tagattttat atacaatttg tatctttcaa atcattgatt tgaattttag
     1621 atttaatcat gttacaatta aaaatgaaat caaatagaag aggaagatgc aaacgtgggc
     1681 acactattag caacaagatt aaaaaataga cgaaaagaat taaaaatgtc tcagcgagaa
     1741 ctagctgaag gtatctgtaa acaggggcaa atcagtcgat tagagagcgg agagtttact
     1801 cctggagcag atttcttgca tgcccttgct aagaagttaa aagtcagtat ggattatttt
     1861 tttgatgagc aggttgtaga gaaagttgag gagttatcag aatttaagaa attagcacag
     1921 acatttatta caaatcgcaa ttatgagtct ttgaaatata tatatgaatt ggagaatgta
     1981 aaagctcacc gcctatcttt agcagataaa atctacatgg aatggataaa atctctgata
     2041 gatttttatt tttacggaca gaaagaagat gcgattgtac gattagaggg ggtattatca
     2101 cagttaagtg tatctgattt gaactatctc caagtttcaa acaccctatt caatttttat
     2161 tatgatattg gagatttagg tcgtttcaat aaaattcgtg aaaaactaga gtatcaagta
     2221 aatcacctca atttgagtac aatcgaagag ttagaactat ctattaagtt taactacaac
     2281 gtttgtcgtt atctatggtt acagaaaaat attgaagaag ctattactaa aattacagct
     2341 actataaaac aatgtaaggc ttacagaacg aattatcttt tggctgattt gtacttattg
     2401 atgggaaatg taagtgaaaa tttttcttct aaaagttcgg tgaaagaata ttttgagacg
     2461 gcatattttc tatacaaact tgaggagaac atgtcaatga ctctgaaagt tgagcattac
     2521 attgcagata taacagaata atgaatacgg tgttcaagtg agcatcgttt ttcaaaccta
     2581 gttcagatac aaaaaagtat caaataaaaa aaaataaaaa aacattataa aaacaattga
     2641 caagctaatt ttgaagtgat aaaataaatg caagaaaaca aaaggagagg tatatgagaa
     2701 gtttgtttaa gaaaatagtt gctgtattag ttattggctt aattctgtta ggaattgcga
     2761 gaacacctca agttcataag atggctagag ggattgatcc tggtcctgcg aattttattt
     2821 agaaatcaat ttctactaat tgagtactaa ttgagtatta atgggtaaaa agattgtatg
     2881 gataagaaaa atttacttgt attggttact ggttcggtag gtgccagtaa tgtagataca
     2941 tacttatatt atataaaaaa attctataat gttaaagtga tactttctga aaattctaaa
     3001 aaatttataa gtaaggaatt aattagttat ttttgtgata aagtttatga tgaaatattt
     3061 gttgaagagg tagttccgca cgtttttctg ccatatgaat ctgacttact tcttatttta
     3121 ccagctacgg caaatgtgat tggcaaaatt gctaatggta ttgctgatga tttagttaca
     3181 gcaactgttt taaactttaa taaaaaaata attttttgtc ccaatatgaa ctctactatg
     3241 tgggacaatc acatagttca aagaaatgta tcaattctaa aggagttggg acatatattt
     3301 ttatttgagt ctaaaaaaac atatgaggta ggattgcgta aagcaataga ttcaacatgt
     3361 tcaatgttac aaccacagtc gttagtaaaa gaacttatca aattagaaaa tattgtcctt
     3421 gaagagggac attaaaaact actgagaata ttaaggaggg gaaaaaatgg aaaattcatc
     3481 aatcgatgta gatatgctgt tggaagaatt gacacaagaa gcaatggtcg ttgttgctgt
     3541 tgataaggac tgttaattta aacttatggc aatatatgaa aggttactgg atgttttaaa
     3601 ttatgcaggc agtagccttt tattatatac aaatggataa agtaaggata atacaatgat
     3661 taataaaaaa atacaacaag ttgttttgga atcattacag aattttttga atgggaactt
     3721 catttcgcct tgtgtagtct atgattttgg cttgctggaa actgtacttg atgaatttaa
     3781 aaatcaaatt cctgtaacat tcaattacca acttttttat gccgttaaag caaattcaaa
     3841 tgagaagata cttgaattct tagtagataa aattgatgga gttgatgtgg cgtcattatc
     3901 tgaattagat gtggctaaaa aatttttccc accaactcaa atttctgtta atggtcccgc
     3961 attttcttat gaaactttat ataatctgat taaaaaacaa tataaagttg atattaactt
     4021 tttggaacat cttcaacaat tttccccaaa agaatctgtt ggaataagag taacggagcc
     4081 agatgaactt aataatcgta tgagtcgatt tggaataaat atttgcagtg ataattggac
     4141 tagtaattta caaaatcctt taattacacg actgcatttt cattttggag aaaaagatga
     4201 taaatttatt gttaagttag ataaaatatt atttaagtta caagaaatta ataaacttag
     4261 agaggttaga gaaataaatc ttggaggcgg ttttatgaaa ttatttatgg aaaatcgttt
     4321 gaaagaattt tttctatcac ttatggaaat ctataaaaag tacgatattg atagtactgt
     4381 gactacaata atagaaccag gtagtgcaat tacttcattt tctgcctata tgattactag
     4441 cccagttaat gttagtgagg tgaatgagca gcaggttatc acgttagaca catcaatata
     4501 caccaataca ttatggtttg ttccgcatat tattacaacg ttaaattcaa gtagtaaaga
     4561 gcgttatagt actattctct atggtaatac ctgttatgaa catgacaagt ataaaatgaa
     4621 agtttcgctt ccaaggttaa ctcaaaatag cagtatagtg ttttttcctg taggagctta
     4681 tataaaaagc aatcattcaa atttacatcg taatgatttt atgcgggagg tatatttgtg
     4741 gacaaaaaac ttgacatatt agataaagtt aaggaatatt taggaaataa aactactcaa
     4801 attctggata atcaatataa agaatttttg aaacttaatg atataaggcg agcgtttggt
     4861 atttcagaaa aagtattaaa caattctttt aattttacga gtaaagaatt taatgattta
     4921 attaataacg aaaattattt attcgaatat gcatgtagaa ttagagagga atggagaaaa
     4981 aaatgcttta atcattctta tcgttttcta tgctcaccta taattacaga tgattttctt
     5041 aacacgaaga cattgagaag tagccaaatt gaatataaat atgagcgata tttatcgaaa
     5101 agttcgatag gcgatagagc ggttgatggc tttgtttcct tcaatacttt aacagctaat
     5161 ggtatgtctg ctattaaact atgtcttgag atattaaact ctattttctt caagaagaag
     5221 attgatttat tatattcaac cggatattat gaaacaagat ttttattaaa taatcttgct
     5281 aaatcaggta ttagttgcta tgaggtaagt aattgtgaat tggataaaga taaattttat
     5341 aatgtattca tgatggaacc caatcgagcc gatttaacat tacaaaaaac tgatttcaag
     5401 atagtagaat attttgttaa gtataaaaat aattcaataa aagtcgttat tttagatatt
     5461 tcatatcaag gttctaattt taaattagta gaatttttag agaaatttaa atttgcgaat
     5521 gtaattattt ttgtggtacg atctttgata aaattagatc aaatgggatt agaattgaca
     5581 aatgggggaa taatagaagt gtttattcct aatcatttga gaaagttgaa aaattttatt
     5641 gaagaggaat tcaataaatt tagaaattct cacggagcta atctaagcct ctatgaatac
     5701 tgtttgcttg ataattcttt aaccttaaaa aatgattgga actattctga tttagttatg
     5761 aaatttacga gtaattttta tgctgatata aaagacttgt tcatggaaaa ttctgatatt
     5821 gaaatcatcc atgaagaggg agtacctttt gtatttttag atttaatagg tgaaggtaaa
     5881 aaagaatatg aaatgttttt tcaatggtta aacttctttt acaaacagct tggaatcaca
     5941 ttgtatgcta gaaatagttt tgggtttcgg aatctaacag tagagtattt tggaattatt
     6001 gggacagaaa gatatatatt taagatttgt ccaggtgttt ataaagggtt aagttattat
     6061 ttgatgaaat ttttattaaa atctttttca aatgaatatt taaaaactac tgatgaggtt
     6121 aatagatgaa aaatttgata aagttgctaa taattagatt gattgttaac ttagcagaca
     6181 gtgtatttta tatagtagca ttgtggcacg ttagcaataa ttattcttcg agcatgttct
     6241 taggaatatt tattgcagta aattatctac cggatttgtt actaatcttt tttggaccag
     6301 ttattgacag agtaaatccg caaaaaattc ttataatatc aattttggtt caattagcag
     6361 tggctgtaat atttttatta ttattaaacc aaatatcatt ttgggtgata atgagtctag
     6421 tgtttatttc agtaatggct agctccataa gttacgtgat agaagatgtg ttgattcctc
     6481 aagtggtaga atatgataag attgtatttg caaattctct ttttagtatt tcgtataaag
     6541 tattagattc tatttttaat tcattcgcat catttttaca ggtggcagta ggatttattt
     6601 tattggttaa gatagatata ggcatatttt tacttgctct atttatattg ttgttgttaa
     6661 aatttagaac tagcaatgcg aatatagaaa acttctcttt caaatattac aagagagaag
     6721 tgttgcaagg tacaaagttt attttaaata ataaattatt atttaaaacc agtatttctt
     6781 taacgcttat aaactttttt tattcatttc agacagtagt tgtaccgatt ttttctattc
     6841 gatattttga tggtccgatt ttttatggta tttttttaac tattgctggt ttgggtggta
     6901 tattgggaaa tatgctagcg ccaatcgtaa taaaatattt aaaatcgaat caaattgttg
     6961 gtgtatttct ttttttgaac ggctcaagtt ggttagtagc aattgttata aaagactata
     7021 ctttatcact tattttattt ttcgtttgtt ttatgtctaa aggagtcttc aatattattt
     7081 ttaattcgtt gtaccaacaa atacctccac atcaacttct tggtagggta aatactacca
     7141 ttgattctat tatttctttt ggaatgccaa ttggtagttt agttgcagga acgcttattg
     7201 atttgaatat tgaattagtg ttaattgcta ttagcatacc ttattttttg ttttcttata
     7261 ttttttatac ggataatgga ttgaaagaat ttagtatata ttagaaatgt ttatgttcat
     7321 tcaaaagcat aatgactata actgaaaaag aaaagtgata tctttaaggt tgttcttctt
     7381 ggtggtgaga ttcgtgagac aacccaagct tttgtcggaa agattaccaa tgctttgatg
     7441 gataggatgt actttagcaa gatgttttta gtggtaacgg tatcgtggat ggacgtgtaa
     7501 taacctcttc tttcgaggag tattttacta aaaaactagc cttggagcgt tccccagaaa
     7561 cggacttact cattgactct tcaaagattt ggggagaaga ttttgcttca tctgttcctt
     7621 gaaaaaagtc acagcagtca tcacagacga tagtactgaa caaaactatg aagagttaga
     7681 aatttatacg caggtgattg tataaaggat ctggaaatag ataagaagtt gattagtatt
     7741 gacctaggtg gtacaaatat taagattact gttctttcaa atgacggtga gattgaaact
     7801 ttgtggagta ttacaacaga tacaagtgag aaaggttctc aaattatatc ggacatcatc
     7861 agttctatta aaaataaatt gaccgaacgg aatattcctg atagcgacct tcttggaatc
     7921 ggtatgggaa gttgctcatc atactttcct tgtaaatcat aggggctata aactctccgt
     7981 ctacttgtcc tgcaacaatt gaagtctgct caaaacgccg tccgctaatc ttttcataga
     8041 ctttctccct tttaggagcc tagctttcta gtttgttctt tgatttttat tgagtatacc
     8101 actattttac tccctctggc aagggacttt gtctatgtgg agggattggg ctcctatgtg
     8161 gtggagcttt tctgttcttt ctgaaatatg gtataatagc actaatcaat ttctaggaaa
     8221 atagatacgg aaaggggctg aaagatgtct catattattg aattgccaga gatgctggca
     8281 aaccaaatcg cagctggaga ggtcattgaa cgtcctgcca gcgtggtcaa agaattggta
     8341 gaaaatgcca ttgacgcggg ctctagtcag attatcattg agattgagga agctggtctc
     8401 aagaaaatcc aaatcacaga taacggttat ggaattgccc acgatgaggt ggagttggcc
     8461 ctgcgtcgcc atgcgaccag taagataaaa aatcaagcag atctctttcg gattcggacg
     8521 cttggttttc gtggtgaagc cttgccttct attgcgtctg ttagtgtctt gactctgtta
     8581 acggcggtgg atggtgctag tcatggaacc aagttagtcg cgcgtggggg tgaagttgag
     8641 gaagtcatcc cagcgactag tcctgtggga accaaggttt gtgtggagga tctctttttc
     8701 aacacgcctg cccgtctcaa gtatatgaag agccagcaag cggagttgtc tcatatcatt
     8761 gatattgtca accgtctggg cttggcccat cctgagattt cttttagctt gattagtgat
     8821 ggcaaggaaa tgacgcggac agcagggact ggtcaattgc gccaagcaat cgcagggatt
     8881 tacggtttgg tcagtgccaa gaagatgatt gaaattgaga actctgacct agatttcgaa
     8941 atttcaggtt ttgtgtcctt gcctgagttg actcgggcta accgcaatta tatcagcctc
     9001 ttcatcaatg gtcgttatat caagaacttc ctgctcaatc gtgctatttt ggatggtttc
     9061 ggaagcaagc ttatggttgg acgttttcca ctggctgtca ttcacatcca tatcgaccct
     9121 tatctagcgg atgtcaatgt gcatccaact aagcaagagg tgcggatttc caaggaaaaa
     9181 gaactgatga ccctggtttc agaagctatt gcaaatagtc tcaaggaaca aaccttgatt
     9241 ccagatgcct tggaaaatct tgccaaatcg actgtgcgca atcgtgagaa ggtggagcaa
     9301 actattctcc cactcaaaga aaatacgctc tactatgaga aaactgagcc gtcaagacct
     9361 agtcaaactg aagtagctga ttatcaggta gaattgactg atgaagggca ggatttgacc
     9421 ctgtttgcca aggaaacctt ggaccgattg accaagccag caaaactgca ttttgcagag
     9481 agaaagcctg ctaactacga ccagctagac catccagagt tagatcttgc tagcatcgat
     9541 aaggcttatg acaaactgga gcgagaagaa gcatccagct tcccagagtt ggagtttttc
     9601 ggacaaatgc acgggactta tctctttgcc caagggcgag atggacttta catcatagat
     9661 cagcacgctg ctcaggaacg ggtcaagtac gaggagtacc gtgaaagcat tggcaatgtt
     9721 gaccagagcc agcagcaact cctagtgccc tatatctttg aatttcctgc ggatgatgcc
     9781 ctgcgtctca aggaaagaat gcctctctta gaggaagtgg gcgtctttct agcagagtac
     9841 ggagaaaatc aatttattct acgtgaacat cctatttgga tggcagaaga agagattgaa
     9901 tcaggcatct atgagatgtg cgacatgctc cttttgacca aggaagtttc tatcaagaaa
     9961 taccgagcag agctggctat catgatgtct tgcaagcgat ctatcaaggc caatcatcgt
    10021 attgatgatc attcagctag acaactcctc tatcagcttt ctcaatgtga caatccctat
    10081 aactgtcctc acggacgtcc tgttttggtg cattttacca agtcggatat ggaaaagatg
    10141 ttccgacgta ttcaggaaaa tcacaccagt ctccgtgagt tggggaaata ttaaaagtat
    10201 aaaaaagtct gggaaaaatt ttcaaaatca gaaaaacgca taaaatcagg tgttcaaaaa
    10261 ccttgatttt atgcgtttta tcatggaaat agttacttca tgttttccta attcttttcg
    10321 aaactctttt taaaccacgt cagttttatc agtaatctca aaacagtgtt ttgagctaat
    10381 tttgccagtt ttatctgtaa catcgaagtt gtgtttgacc actctgcgac tggtttccta
    10441 gtttgctcta tgattttcac agagtattaa attgcgattt tgccaagttt ctttattcgt
    10501 ctaaaagtag agtctgttct atgcgtctaa tgtacgaatt aggttgacca tttcaatagc
    10561 tccttgtgca cactcagaac ccttatttcc tgctttggta ccagctcgtt ctatggcttg
    10621 ttcaattgta tctgtcgtta gcacaccaaa cataacagga atttcgctat ttaaactgat
    10681 ttgggcgatt cccttagata cctcgctaca tacataatca taatgacttg tattccctct
    10741 aatgacagct cccaagcaga taattgcatc atatttttta ctttttgcca tttttgatgc
    10801 aatcagtggt atttcaaaag ctcctggaac ccaggctacc tctatatctt tctcgtttac
    10861 attctctctt ttgagattat ctagtgctcc agataataat tttgaagtta taaattcatt
    10921 aaatctcgct acaacaatac ctattttaat attgtttgct actaaattac cttcataagt
    10981 gttcatttat ttttcctcca tatttaaaat gtgacccatt cgatttttct ttgtttctaa
    11041 ataaaaacta tcgtaaggat tggcttctat ttcgattgat attctactgg aaatggtaat
    11101 tccatatttt tctaactgtt caaccttgtc aggattattt gtcagtaaat gaagtgactg
    11161 aagtcccaga tctttaagca tttgtgctcc aatatgatat tctcttaaat caccttcaaa
    11221 gcctaatgca agattggcat caagcgtatc catgccttga tcttgtaaat gataggcttt
    11281 taatttattg ataagtccaa ttcctcgtcc ctcctgtcgc aagtaaagta agacacccga
    11341 accattctca acaatcattt tcatagcttt atcgaattgc tgtccacaat cgcaacgtaa
    11401 agagcctaaa acatctcctg ttaaacattc ggagtggacc cgacataata cattggcttc
    11461 atcctctata tttcccataa taagagcaag atgatgttcc ccatttagtt tatctatata
    11521 gctaattgct ttgaaattac cgtatctagt aggcatattg acagttgaaa ctcgttctac
    11581 cagctgatca tatacttttc tatattcttg taattctttg atggtaatta gtggaatgtt
    11641 gtgtttcttc gagaactgaa ttaaatcatc tgttctcatc attttgccat catgattcat
    11701 tatttcacaa cataggccac actcttttag tccagctaat tttaataaat caacagttgc
    11761 ttctgtgtgt ccatttcttt ctagaacacc accttttttt gcaattaaag gaaacatgtg
    11821 tcctggcctg cgaaaatcag agggtgttat atcttcagct acacacatac gtgcggtcag
    11881 tcctctctcc tcggcagaaa tacctgtggt cgtttcttta taatcaattg aaactgtaaa
    11941 agcagtctta tgattatctg tattgttttc aaccataggt gaaagcatta attgattagc
    12001 taaactttcg ctcataggca tacaaattaa tcctttggca taagtagcca taaaattaac
    12061 attttctgtt gtagctgctt gtgcagaaca aattaagtct ccttcatttt ctctatcctt
    12121 gtcgtctata acaagaacaa gtcgtccctt ctgcaatgct tctaatgctt cttgtatttt
    12181 tcgatattcc attgactgat tatcctttct gctaaaatcc attttgatat aatagttcct
    12241 tagatatttc tgattttgga gagttatcca tcagtttttg cacatattta cctaagatat
    12301 cattttcaag atttactgta ctcccgactt gtttactctt aagaatggtt tgttccaagg
    12361 tatgagggat aacagatact gaaaagttta ctttggagac tttagcgaca gtcagactaa
    12421 tgccgtcaat tgtaatagat cctttttcaa ctattaaatc taaaatttct ttttgtgtgt
    12481 tgatttgata ccatacagca ttatcatctt tttttattga cgagattttt cctgtaccat
    12541 caatgtgtcc tgtaacgacg tgacccccaa gtcgaccgtt gacagataag gctctttcta
    12601 gattcacctc acttccatgt tttaatagag taagagctgt tcgactccat gtttcattca
    12661 ttacatcaac tgtaaaggat tgatgattga aatgagtaac tgtaagacag ataccattta
    12721 ctgctatact atcgcctaaa tggatatccg ttaatatttt tgaggcttta attgatagtt
    12781 tacaattacg agagtctttc tgtattcttt caacttttcc gatttcttca attattcctg
    12841 tgaacatgga taaatcactt cactttctat gagatagtca tttcctattt gagaaaaagc
    12901 ataaggtttc aatctaatag cgtcatttgg caaagaaatg ccttcacctc cgacaggaaa
    12961 cttggcactg cctccaaaaa tttttggtgc aatatatatt ttcagctcat caacaatttg
    13021 ttgttccaaa gcactccaat tcattagact gcccccttct agaactaggc tatcaatctg
    13081 catgtttcct agatgttgca ttaaactcga taagtctata tgattgcctt ttttctttat
    13141 ggaaagtatt tcacagccat gattttgata tagcttcatt ttatttttgt cttcagagga
    13201 agtggcaatg taagttttaa tatcatttgc tgtttttacg attttagagg taagaggagt
    13261 tcgtaaatgt gtatcgcata tgatacggat aggatttttc ccttcctcca atctacatgt
    13321 cagcaaagga tcgtcttgaa taacagtatt gactcccacc ataattgcac taacatggtg
    13381 tcgtaactga tgcacatgct ttcttgcttc ttcttcagta atccatttgg attgatttgt
    13441 tttagtggct atttttccat ccattgacat tgcatatttc ataaaaacat agggtacatg
    13501 ctgggtaata tactttctaa aactttttat taagttaaga cactcatttt ctaaaattcc
    13561 aacagtaact tgaagattat tttcctcaag tatctttact ccttttccag atacaatagg
    13621 attacagtct aggcttccaa tgactactct tgtaatacca ctatcgatta tagcatctat
    13681 acagggaggt gttttcccga agtgacaaca gggttcaagt gttacataaa gcgtcgctcc
    13741 gacaggggat tctctacagt ttttaagagc atttctctca gcatgtgggc caccaaaaaa
    13801 ctcatgataa ccttgtccga tgatgtgatt atcttttaca ataactgcgc cgaccatagg
    13861 attgggattg acgtaaccag cccctttttg tgccagtttt attgctaatt tcatatattt
    13921 tgaatcgctc atctcactac ctccaaaaaa aatatacctt gaatagggga ctactcaagg
    13981 catacaaaag aaaacttatg cgattaacaa aaatactctg aaatgacaag taatcatttc
    14041 agagcacgca aaaagcacaa atatactttt atcttctttc atccagacta tactgtcggc
    14101 tttggaattt caccaaatca tgcctttcgg ctcgtgggct ataccaccgg tagggaatta
    14161 caccctgccc tgaagatagt tattcaatta cagatgatta tagtacttaa ttttgaatat
    14221 gtcaacagat aaataccgat tgtttttgat atactgtatt tgtgataatc gattctcgct
    14281 cctcggataa agaaaatatg atatactaga taaacgaaat aagagagaag gaatactatg
    14341 tacgcatatt taaaaggaat cattaccaaa attactgcca aatacattgt tcttgaaacc
    14401 aatggtattg gttatatcct gcatgtggcc aatccttatg cctattcagg tcaggttaat
    14461 caggaggctc agatttatgt gcatcaggtt gtgcgtgagg acgcccattt gctttatgga
    14521 tttcgctcag aggatgagaa aaagctcttt cttagtctga tttcggtctc tgggattggt
    14581 cctgtatcag ctcttgctat tatcgctgct gatgacaatg ctggcttggt tcaagccatt
    14641 gaaaccaaga acatcaccta cttgaccaag ttccctaaaa ttggcaagaa aacagcccag
    14701 cagatggtgc tggacttgga aggcaaggta gtagttgcag gagatggcct tcctgccaag
    14761 gtcgcagtgc aagcaagtgc tgaaaaccaa gaattggaag aagctatgga agccatgttg
    14821 gctctgggct acaaggcaac agagctcaag aaaatcaaga aattctttga aggaacgaca
    14881 gatacagctg agaactatat caagtcggcc cttaaaatgt tggtcaaata ggagcagaga
    14941 atgacaaaac gttgttcgtg ggtcaagatg accaacccac tctacatcgc ctatcatgat
    15001 gaggagtggg gccagcccct ccatgatgac caagcgttgt ttgagttatt gtgtatggaa
    15061 acctatcagg caggcctgtc ttgggaaacg gtactcaaca aacgccaagc tttccgagaa
    15121 gcctttcata gctatcaaat tcactcagtc gcagagatga ctgacactga attggaagcc
    15181 atgctggaga atccagctat cattcgaaat agagccaaga tttttgctac acgcgctaac
    15241 gcccaagctt ttctacagtt acaggcagag tacggctctt ttgatgccta tctttggtct
    15301 tttgttgagg ggaaaactgt cgttaacgat gttcctgatt atcgccaagc cccagctaaa
    15361 acacccttat ctgagaaatt agccaaagat ctcaaaaaac gagacttcaa gttcacaggc
    15421 ccagtcgccg tattgtcttt tctacaggct gcagggctag ttgatgacca cgagaatgat
    15481 tgtgagtgga aaggtcttaa atgatgtcta acaaaaataa gggaattctg atttttgcga
    15541 ttctctatac agtcctcttt gtgtttgatg gcgttaaatt gctggcttct ttaatgccat
    15601 ctgccattgc aaattatctt gtttatgtag ttttagctct atatggctcc ttcttattca
    15661 aggatagatt gatccaacaa tggaaggaga ttagaaagac taaaagaaaa ttcttctttg
    15721 gcgtcttaac aggatggctc tttctcattc tgatgactgt tgtctttgaa tttgtatcag
    15781 agatgttgaa gcagtttgtg gggctagtcg gacaaggtct aaatcagtct aatattcaaa
    15841 gcacttttca agagcaacca ctactgatag ctgtttttgc ttgtgtcatt ggacctctgg
    15901 tagaagaatt atttttccgt caggtcttat tgcattactt gcaggaacgg ttgccaggtt
    15961 tactaagcat tattctggta ggacttgttt ttgctctgac tcatatgcac agtttggctc
    16021 tatcagagtg gattggtgca gttggttact taggtggagg ccttgccttt tctattattt
    16081 atgtgaaaga aaaagagaat atctactatc cactacttgt tcacatgtta agcaacagcc
    16141 tctccttaat cattttagct atcagtatag taaaatgaaa taagaacagg acagtcaaat
    16201 cgatttctaa caatgtttta gaagtagatg tgtactattc tagtttcaat ttgctgtaat
    16261 atgtgatgaa aatgccagta atgataccga gaaaaaagct gagaaacttt tcccagcttt
    16321 atttgttata gtcaaagcga atgacttgtt cctgtgcatc tacatgagca tggaccccaa
    16381 agggtacaat tgctcttgga gttgcgtggc cggcattcag attatagaca atcgggatat
    16441 tgctgtcaat gatatccaat agtgcctctt tatagtcgtc atggaaagtt tcatccatag
    16501 gttttccgac caagagtcca ttgatgaccg cgaatatgcc agtgtccttt aaagttagca
    16561 acatcttttt gaagtcttct ggcttaggct tttcttcgct tgtttcgagc aagaggattt
    16621 tcccttccca gtctgacaag tcagggaaaa gtttgtattt ttggcagagc tccgtgctat
    16681 ctgcgtatcg agagttgtca aagatatcgt agagggattc gaggcaacca ccgaggattt
    16741 tcccctcgaa tagtgccctt ccttgcaaca agtcaaaacc tgtatttgta tgactgacac
    16801 gaggtgttcc cagggccgtg ggactaaaat cagttcgttc ctcataccaa acgtcactag
    16861 ggcggatttc tgaaattctt cccgtctcaa tcaattcttt aaagtagtga aggctatagg
    16921 ctagcatttc tttgtctaat tcacaaatgt ctgctaaaaa ggattgacca taaaaagtct
    16981 tgattcctaa tttatgcaac atgaggtggt tcatggttgt atccgagaag ccaagaaaaa
    17041 ttttttgctt gataaccttt tggagttggt cattttcaaa aagataaggt agcaagcgat
    17101 aggtatcgtc tccaccgatg gcacatagga tcatgtcgat gctatcatca gaaaaggcat
    17161 gaatcaaatc ctctgcacga gcttcaggat ggtccttgat aaagtctaat ccttttaacg
    17221 aatggggcaa aaagatggga ttgagtccca gatccttgag acgttggata cccaagtcca
    17281 cttcgtgttt gacaaaatcc tctccgataa tgccactaga taaactaaca ataccaatag
    17341 tagaaaccat atctcatcct cctagaaata gattgagcct attttatcac aaaatataag
    17401 agaaagctat gtgggatttc agaagaatac ttttaatact cttcgaaaat ctcttcaaac
    17461 cacgtcagtt ttatctgcaa cctcaaagct gtgctttgag caacctgcag ctagcttcct
    17521 agtttgctct ttgattttca ttgagtataa ctcaaaaaag taagtgaaaa agcaaccgca
    17581 cctgcagttg cttttatcgt tttcttattc ttgatagcgt gttggtcctg cacttgcact
    17641 acggatattc aagcgtttct tgagatagaa gcgaagggct aggagggctg ctccaataat
    17701 agctagtggc aatggatcca gtactgggtt aaggctagct ggtaggaagc ttgttgcaaa
    17761 gaagacaagc aaccaaagga acacagaagc taggataact agtacagatt tccagaaagg
    17821 tggacgttga ctgcgatcca tatctggtcc atagtattgg taaacaaagt agtacatcaa
    17881 gtagaaggca aatccaccaa ccagtccaac taatagaaga gtaatcaatc catagccgaa
    17941 agcttgatct gccgcaaaga aggttgtgag ggcgctgaca agggcaaaga ggctagtgat
    18001 gaaaagagct gagtccataa tcatcagttt tgggtcatca ttttcttttg gatgctcttt
    18061 ttcgtactgc tctttgacag tgaagctatg agcccaatga gttggtgcgc cgtataggga
    18121 acgggcagtt gtacctttag attgctcctc aaggatttgg ggaatgactt cctcaaaaat
    18181 agtctggatt tcagcgtctg ttttcccatc tttgatgaat tgttgggtag caatgtggac
    18241 aaactcttgg tttttcttag ttaatttttg tagatcaatt tgagacatag gaactccttt
    18301 tagaaccatt ttttatggat gagatagaga gtgagcgaga cactcatagc aaaggcgata
    18361 aagacgatta accagaaggc atttggctct ccgtttaggg gaatttcatt atccttaaag
    18421 ttcatcccgt aggcagaaaa gaccatggtt gggatggaca tgacgatggt cacaagggcc
    18481 aaggttttca tgatgttgtt ctggttgtta gaaatgatag aggcaaaggt ctctgtcata
    18541 gaatgcaaga cgtttccata aatatctgcc atctcgatgg cctgttgggt ttcaatcagg
    18601 gtgtcttcaa gcaggtcttc gtcctcaagg tatttcttga tattgctggt tgaactggtc
    18661 aatttcttaa tcacgcgctc atttgttttg agggaggcct tgaaatagac gatagttttt
    18721 tccaattcca tgagctcaat caattcttca ttacgagttg attgatgcag ttgactttcg
    18781 atttgttcac tcttgcggtc gattgaacga agggctgtta ggtaaagctc tgcattgcga
    18841 taaagaattt gaaagataaa acgtgaacgc atgaaggtat agaaattacg caatcgacgg
    18901 ttgataaaga catcaaggac aggtagtggt tccaaacacg tagtgataat ggtttcctca
    18961 gtgatgataa taccaagcgg gatggttacg tagtaggtgc ggttatttct ttcctccgtg
    19021 accggcacgt ctacgataat cagggtatac tcgtcttcaa tggtaatacg agacatttct
    19081 tccgcatcga gcggtgctcg aaggtcggca atatcaatat cgaaggtgtt ggcgatttcg
    19141 agtgattcat tttgagtcgg attgacgaga ttgatccaag tacccggttc aagcgtatcg
    19201 atctctttaa attcagttgt tgtagagaga aaaacttgtt tcatatccct tatcctttct
    19261 catttttcag attttttcac actgtactat tatactacaa aatcggcctt ttgggtaata
    19321 gaatctcact ttttttggta taatggtaag caataatgga ctagaaagaa caaagatgca
    19381 agataaaatt gtcattcatg gggcgcgtgc ccataattta aaaaatattg atgtggagat
    19441 tccgcgagac aagttggttg tcgtgactgg cttgtcaggt tcagggaagt ccagtttggc
    19501 ttttgatacc ctctatgcgg agggacaacg tcgctatgta gagagtttgt ccgcctacgc
    19561 tcgtcagttc ttgggaaata tggaaaaacc agatgtagat gccattgatg gtctcagccc
    19621 agctatttct atcgaccaga aaacgactag caaaaaccct cgctcgacgg tgggaacaac
    19681 gactgaaatc aatgactatc tgcgtctcct ctacgcgcgt gtggggacgc cttactgtat
    19741 caacgggcat ggggctatca aggcttcttc tgtggagcaa atcgttgata aggttttgga
    19801 gttacctgaa cgccagcgct tgcagatctt gtctcctgtc atccgcaaga aaaaaggcca
    19861 acataagagt gttatcgaga aggttcagaa agacgggtat gttcgtgtcc gtgtggatgg
    19921 ggaagtctat gatgtgaccg aagtgccaga gttgtctaag agcaagcaac acaatatcga
    19981 tgtcgtggtt gaccgtattg ttatcaagga gggcattcgt agtcgtctct ttgattccat
    20041 tgaggctgcc cttcgtattg cagaaggtta tgtcattatc gacaccatgg acaactctga
    20101 gttgttgttc tctgagcatt atgcctgtcc agtttgtggt tttactgtcc cagagttaga
    20161 gcctcgtctc ttttctttca atgctccttt tggctcttgt agtgagtgtg acggcttggg
    20221 catcaagctg gaggtggata ctgatttggt agtgccaaat gccagcaaaa ccttacatga
    20281 gggagcgctg gcaccttgga atcctatctc atccaactac tatccaaaca tgctagagca
    20341 ggccatgacg gcttttggag tggctatgga taagcctttt gaggacttgt cagaagaaga
    20401 caagaacttg attctctacg gctcagatgg taagaaattc catttccact atgagaatga
    20461 atttggtggc gtgcgcgata tcgacattcc gtttgaggga gttatcaata atatcaaacg
    20521 tcgttaccat gaaaccaata gcgattacac tcgcactcag atgcgcctct acatgaatga
    20581 gctgacttgc ggaacctgtc acggttatcg tctcaatgac caggccttgt ctgtccgtgt
    20641 gggtggtgag caagggccac atatcggaga aatttcagac ctgtctatcg cagatcactt
    20701 ggacttggtg agccagttaa ctttgtctga aaatgaagcc atcattgctc gtcccattct
    20761 caaggaaatc aaggatcgtt tgaccttcct taataatgtg ggtcttaact atctaaccct
    20821 gtcacgttca gcaggaaccc tttcaggtgg ggaaagtcag cgcattcgtt tggcaaccca
    20881 gattggttcc aacctatcag gcgtcctcta tatcctagac gagccgtcaa tcggtcttca
    20941 ccagagagac aatgaccgcc tgattgccag tctgaaaaag atgcgtgact tgggcaatac
    21001 tcttatcgtg gtggaacacg acgaagatac catgcgtgaa gctgattatc tgattgacgt
    21061 tggtcctggt gccggtgttt ttggtggtga gattgttgca gcaggtacac ctaagcaagt
    21121 ggctcgcaac agcaagtcta tcacaggtca gtacttgtca ggcaaacgtg tcatcccagt
    21181 accagaagag cgccgtgtcg gaaatggtcg ttttattgaa gtgataggag cgcgtgagaa
    21241 caacttgcaa aatgtcacgg ctcgctttcc actaggaaaa tttatcgcag tgacaggtgt
    21301 gtcgggttca gggaaatcga ctctaatcaa cagcattctc aaaaaagcca ttgcccagaa
    21361 gctcaaccgt aattcagaca aacctggtaa gtttaagact attacaggga ttgagcatgt
    21421 cgaccgtttg attgatattg accagagccc tatcggacgg acgccgaggt ctaacccagc
    21481 tacctataca ggagtttttg acgatatacg tgaccttttt gctcagacaa atgaagccaa
    21541 gattcgaggc tacaagaagg gacgcttcag tttcaacgtc aagggaggtc gctgtgaagc
    21601 ttgctcaggt gacgggatta tcaagattga gatgcacttc ttgccagatg tttatgtggc
    21661 ttgtgaagtt tgccacggaa cccgctataa cagtgaaacc ctagaagttc actacaagga
    21721 aaagaatatt tcgcaggtct tggatatgac ggtcaacgat gcggtagaat ttttccaaca
    21781 cattccgaaa attcaacgca aactccagac catcaaggat gtagggctag gctatgtgac
    21841 cttgggacag ccagctacca ccctttctgg gggagaagcc caacgtatga agttagctag
    21901 cgaactccac aaacgctcga caggaaaatc tttctacatt ctggatgaac cgacgacagg
    21961 gcttcataca gaggacattg ctcgcctgct caaggtttta gctcgctttg tagacgatgg
    22021 caatacagtc ctcgtcatcg agcacaatct ggatgttatc aagacggcag accatatcat
    22081 tgacttggga cctgagggcg gtgtcggtgg tggaaccatc atcgtaacag gaactccaga
    22141 agaagtagct gccaacgaag ccagctatac aggacactat ttgaaaggaa agttacatca
    22201 tgaataaacg cgtacaagca tttctagcta aaatgcaaga aaaagaacta gatggtgtca
    22261 tcatcaacaa tcttaaaaac gtctattatt tgactggttt ttggggctca aacggaacag
    22321 tctttatcag ccgtgaccgt caggtattag tgacagactc tcgctatatc atcgcagcta
    22381 agcaagaaac cagtggtttt gagattgtgg ctgatcgtga tgaattggct gtcattgcag
    22441 gaattgttaa ggacatgggc ttgactcgta tcggttttga agatgagatt tcagtgtctt
    22501 attaccaccg tatgcaggca gcttttgcag gtttgaactt gcttccacaa actcagtttg
    22561 tggaaggtct tcgtatgatt aaggatgagg cagagattgc agcgattcgc aaggcttgtt
    22621 ctatctcaga ccaagctttc cgcgatgcgc ttgactttat caaaccagga aaaactgaaa
    22681 ttgagattgc caacttcctt gatttccgca tgcgtgagtt gggagcatct ggcttatctt
    22741 ttgatacgat cctagctagc ggtatcaatt cttctaaacc ccatgcccat ccaatgcaca
    22801 aaccagtgga gttgggagaa gccattacca tggacttcgg ctgtctctat gaccactatg
    22861 tcagtgatat gacccggact atctatctag ggcatgttag cgatgagcag gcagagattt
    22921 acaatacggt tctaaaagct aaccaagcct tgattgacca agctaaggca ggcttaggtt
    22981 tccgtgactt tgacaaaatc cctcgtgata ttatcattga ggcaggttat ggtgactact
    23041 ttactcacgg cattggccac ggtattggtc tggatatcca tgaggaaccc tactttagtc
    23101 agacttctac agaaactatt aagacaggta tggccttgac cgatgaacca ggtatctata
    23161 tcgaaggcaa atatggcgtt cgtatcgagg atgatatcct gattacagag acaggttgtg
    23221 aattattgac cctagctcca aaagagttga tagtcattta gttgtttgtc aagaaaaaag
    23281 tacgaaaatg acgaaaaaag tcaaaaaaaa tt
//
LOCUS       DAVBIC010000037        22314 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.037, whole genome shotgun sequence.
ACCESSION   DAVBIC010000037 DAVBIC010000000
VERSION     DAVBIC010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22314)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22314)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22314
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.037"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            complement(160..2118)
                     /gene="ftsH"
                     /locus_tag="VQ664_001424"
     CDS             complement(160..2118)
                     /gene="ftsH"
                     /locus_tag="VQ664_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HET2789577.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEETGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMFGAQSPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNREIHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDEK"
     gene            complement(2134..2676)
                     /gene="hpt"
                     /locus_tag="VQ664_001425"
     CDS             complement(2134..2676)
                     /gene="hpt"
                     /locus_tag="VQ664_001425"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HET2789578.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKAREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            complement(2680..3957)
                     /gene="tilS"
                     /locus_tag="VQ664_001426"
     CDS             complement(2680..3957)
                     /gene="tilS"
                     /locus_tag="VQ664_001426"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HET2789579.1"
                     /translation="MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNINVEDLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEEEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ESIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            complement(3954..5222)
                     /locus_tag="VQ664_001427"
     CDS             complement(3954..5222)
                     /locus_tag="VQ664_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HET2789580.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFGIY
                     FREKLSSPMVYGEVPVYANEDLVVESGKLTPKTSFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKAWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            complement(5342..5710)
                     /locus_tag="VQ664_001428"
     CDS             complement(5342..5710)
                     /locus_tag="VQ664_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HET2789581.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            complement(5703..5969)
                     /locus_tag="VQ664_001429"
     CDS             complement(5703..5969)
                     /locus_tag="VQ664_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HET2789582.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            complement(6027..9536)
                     /gene="mfd"
                     /locus_tag="VQ664_001430"
     CDS             complement(6027..9536)
                     /gene="mfd"
                     /locus_tag="VQ664_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HET2789583.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLTSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIAASRLILPSPNAFKDSIVKISVGEEYAQHAFIHQLKENG
                     YQKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERELAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPIQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTSICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNIDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQRV
                     ERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKGLMELVFDVQNKKDYEI
                     LEGLLIFGESLLEIKEFKEENSI"
     gene            complement(9537..10106)
                     /locus_tag="VQ664_001431"
     CDS             complement(9537..10106)
                     /locus_tag="VQ664_001431"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HET2789584.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     QADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDDYIGI
                     LQSVDKVDDSVKYYLQEKNFEKTMQRYNG"
     gene            complement(10177..11292)
                     /gene="ychF"
                     /locus_tag="VQ664_001432"
     CDS             complement(10177..11292)
                     /gene="ychF"
                     /locus_tag="VQ664_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HET2789585.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYGSEKAVKEAGRLREEGKEYIVQDGDIIEFRFNV"
     gene            complement(11376..11570)
                     /locus_tag="VQ664_001433"
     CDS             complement(11376..11570)
                     /locus_tag="VQ664_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HET2789586.1"
                     /translation="MYQVGNFVEMKKSHACTIKSTGKKANRWEITRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            complement(11635..12771)
                     /gene="dnaN"
                     /locus_tag="VQ664_001434"
     CDS             complement(11635..12771)
                     /gene="dnaN"
                     /locus_tag="VQ664_001434"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HET2789587.1"
                     /translation="MIHFSINKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGIT
                     LIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQN
                     QIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRP
                     ILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDD
                     IETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSME
                     RARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYL
                     IDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN"
     gene            complement(12930..14291)
                     /gene="dnaA"
                     /locus_tag="VQ664_001435"
     CDS             complement(12930..14291)
                     /gene="dnaA"
                     /locus_tag="VQ664_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HET2789588.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYNYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
     gene            complement(14504..15262)
                     /locus_tag="VQ664_001436"
     CDS             complement(14504..15262)
                     /locus_tag="VQ664_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HET2789589.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLEALLTEKKQKKQQKTNHFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK"
     gene            complement(15320..16501)
                     /locus_tag="VQ664_001437"
     CDS             complement(15320..16501)
                     /locus_tag="VQ664_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HET2789590.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGEIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLKSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVVVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            16684..17163
                     /gene="rlmH"
                     /locus_tag="VQ664_001438"
     CDS             16684..17163
                     /gene="rlmH"
                     /locus_tag="VQ664_001438"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HET2789591.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            17207..17280
                     /locus_tag="VQ664_001439"
     tRNA            17207..17280
                     /locus_tag="VQ664_001439"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:17241..17243,aa:Arg,seq:tct)
     gene            17445..17570
                     /gene="comC"
                     /locus_tag="VQ664_001440"
     CDS             17445..17570
                     /gene="comC"
                     /locus_tag="VQ664_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HET2789592.1"
                     /translation="MKNTVKLEQFVALKEKDLQKIKGGEMRLSKFFRDFILQRKK"
     gene            17591..18916
                     /locus_tag="VQ664_001441"
     CDS             17591..18916
                     /locus_tag="VQ664_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET2789593.1"
                     /translation="MDLFGFGTVIVHFLIISHSYHFICKGQINRKELFVFGAYTLLTE
                     IVFDFPLYILYLDGLGIERFLFPLGLYSYFRWMKQYERDRGLFLSLLLSLLYESTHNF
                     LSVTFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDEDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     LKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEV
                     LVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIE
                     LLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFA
                     LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE"
     gene            18913..19665
                     /locus_tag="VQ664_001442"
     CDS             18913..19665
                     /locus_tag="VQ664_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2789594.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            19717..19788
                     /locus_tag="VQ664_001443"
     tRNA            19717..19788
                     /locus_tag="VQ664_001443"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19750..19752,aa:Glu,seq:ttc)
     gene            19794..19867
                     /locus_tag="VQ664_001444"
     tRNA            19794..19867
                     /locus_tag="VQ664_001444"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19828..19830,aa:Asn,seq:gtt)
     gene            complement(19908..20450)
                     /locus_tag="VQ664_001445"
     CDS             complement(19908..20450)
                     /locus_tag="VQ664_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HET2789595.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDMIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSTDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            20629..21396
                     /locus_tag="VQ664_001446"
     CDS             20629..21396
                     /locus_tag="VQ664_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HET2789596.1"
                     /translation="MIGISLIPDLYNIIFLSSMWDPYGQLSDLPVAVVNNDKEASYNG
                     NTMAIGKDMVSNLKENKTLDFHFVDEEEGKKGLEDGDYYMVVTLPSDLSEKTTTLSNI
                     QSTAAYQSLTSEQQTEISDSVSQNSTDSIQSAQSIVALVQDLQGSLENLQNQSSNLST
                     LKNQSNQVSPITSTSLIGLSSGLTEIQGDVTSKLVPASQSIASGVNAYTTGVDKVSQG
                     ASQLSEKNATLTGSLDKLVSGSNTLTQKSSRLTAGVG"
     gene            21481..22161
                     /locus_tag="VQ664_001447"
     CDS             21481..22161
                     /locus_tag="VQ664_001447"
                     /inference="COORDINATES: protein motif:HMM:TIGR03057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HET2789597.1"
                     /translation="MADGSGKLAEGGTKLTSGLEDLQTGLASLGQGLGNASDQLKSVS
                     TESKNAEILSNPLNLSKTDNDQVPVNGIAIAPYMISVALFVAAISTNMIFAKLPSGRH
                     PESRWAWLKSRAEINGIIAVLAGILVYGGVQLIGLTANHEMRIFILIILTSLVFMSMV
                     TTLTTWNSRIGAFFLLILLLLQLASSAGTYPLALTNDFFRSINPWLPMSYSVSGLRQT
                     ISINKSFS"
BASE COUNT         6901 a         4110 c         3643 g         7660 t
ORIGIN      
        1 acagtccctt ggacttcttc atacaattct ttaatcataa ttttcccctt tctagataca
       61 gtctaacaga ttagaaaaca catttgttcc attttctcca ttctgttccc tttagctcct
      121 aaactgcaca aaaaagagag gctccagcct ctctcagggt tatttttcgt cattcatttt
      181 tgactttact tcatcatagg atagtgcatg agattcctct tctactgctt caggcatctt
      241 tcctgtttcg taaagagctt taatttgtgt actatccaat gtttcgtatt tcaataatgc
      301 ttctgcaatt aacttgtgaa tttcacgatt tgactgaata atttcagcag ctttatttcg
      361 tgcctcattt aataatgaac gaacctcttc atcaatttca taagctgttt gttctgaaat
      421 tgatttttga ggactctgtg caccaaacat agcatggttt ccttcatatt gtactgggcc
      481 aagtttttca ctcataccgt actctgtaac cattgcacgc gccatttgtg tcgcttgttc
      541 aaagtcgttt gaagctcctg tagtttggac attaaagata atttcttcag ctacacgtcc
      601 acccattaag ccagccaatt gctctttcat atcttcttta gatagaagca tttgatcctc
      661 tttaggaagt gcaatcatgt atccgcctgc acggccgcgt ggtacaattg taaccttatg
      721 gacaacgcga gcattcgaca agactagacc aacaatggta tgtcctgcct catggtaagc
      781 aaccaattct cgttcttttt gtgaaactgt cttatctttc ttagaaggtc cagcaataac
      841 tctatcttct gcttcatcaa tatctgaagc atcaattatc gatttattgc gacgagcagc
      901 aactaaagct gcttcattca agacattctc taaatcagca ccaacaaagc ctggagtttg
      961 ttgagccact aatttcaaat caacatcttc tgctaaaggc ttgttcttag cgtgaacttt
     1021 caagattgct tcacgacctt taacatcagg acgaccaacc aatacttttc tatcaaaacg
     1081 tcctggacgc aaaagggcag gatcaagtac atctgaacgg tttgtcgcag cgatgacgat
     1141 aatcccttca tttccctcaa aaccatccat ctcaatcaaa agttggttca aggtttgttc
     1201 acgttcgtca ttacctccgc cgagaccgac tccacgttga cgtccaacag catcaatttc
     1261 atcgataaag atgatagctg gtgctgcttt tttggcatcc tcaaaaagag agcgaacacg
     1321 actagctcca actccgacaa acatttctac aaagtcagaa cctgagatac taaagaatgg
     1381 aacacctgct tctccagcga ctgccttagc aagcaaagtt ttacctgtcc ccggaggtcc
     1441 ctccaaaaga acacctgctg gaatacgggc tccaagtttt gtgaatcgtt ttggatcttt
     1501 taagaactca acaacttcaa ctagttcttg tttttcttcc tcagctccag caacatctga
     1561 aaatcttact ttaatatctt ctttatttgc tgctttagcc ttactacgtc caaaactcat
     1621 tggattacgg ccattgcctc ctcccatatt tcccatcata gagaatagga agaagaatag
     1681 aattccaaat ggcacaatgg atacgagtag attaatccat ataccacttg aactttcatg
     1741 cttaacagtt acttctgctt tatggtcagt agcaagtttt tgcaattctg atacggtagt
     1801 atctgcagga agaatagtgc tggtaaattt ctctacctta gtaacagatg gcgtgaaaaa
     1861 ctgaatacct gtttcttctt tacttgtttt aggattttta tagacaccag aaacttcgat
     1921 aacactacca tttggttggt aagttaattc ttttacatta ccatcggtaa tttcttgtac
     1981 caactcagta tagttgattt gctgacttcc tcctgagtta ttcccagaat agaaatactg
     2041 gaatcctgtc acaaggaaaa agataaataa taaccataga aaaggatttt taattaaacc
     2101 attattttgt tttttcatta aagattattc tttctaattt gaatacactt cctctttcaa
     2161 tactccaata taaggaagat tacgataatt ttctttgtag tctaaaccat aacctactac
     2221 aaactcattt gggatagtaa agcaggtata gtctgcctca atttctacaa cacgtccttc
     2281 tggtttatcc aacaaggttg caattttaac agaagctgct tctcttgctt taaacatatc
     2341 tcgcaaattc ttcaaagttt gacctgtatc aatgatatct tctacaaata gaacatgtct
     2401 tcctttgata tcttgagtca catcttgttt aatattgata acaccactac ttgctgttcc
     2461 accatggtag ctagaaacca tcatgaagtc catttcaata tgtgtatcaa tatgtttgac
     2521 caattcagcc ataaaaggaa tagatccttt taaaatccca actaagattg gattttttcc
     2581 tgcatagtct ttagttaatt gagcacctag ttttttagct gcttctgtaa tttcatcgtg
     2641 tgaaacgagg acttttttaa tatcgttttc taacattttt tacctatcta ttttttctat
     2701 ataaagtaca gtgttcatta tatcattttt cgttttttta ctcaaattat tggtcgcaat
     2761 tcccaaaatt gagacaattt caccaaattg ctcaataata agagcagagt ttctcttttc
     2821 catagggatt ttcaaatcaa taaataaacg tctgagtttt tttctatgcc cattttgaat
     2881 caaaacatct cctgtttttc gatgacgaat gtgtatggat gtttcacgtg aaacaggtat
     2941 ttgttgaatt gattcacctt ctaatggaag tccaaaggaa aataaatatc cttgataagc
     3001 tacctgattt tgatagtgta acacaagttc atcttcctct tcatcagcct gcggactgat
     3061 tttacaaatc tgaaactgtt ggtactcttt tatcaattca tagccatttt taatcggatg
     3121 acgatactgg cttttagatt ttaaaatctg ctgaacttca gcaaactgag cttttgtaag
     3181 attcaaatct ggaaaacgat tcagataagt ttgaagtaaa actctttgtg tagactcaga
     3241 gtaagaaaat aactgctgta aatcttccac attaatattg ttagataatt cagctattgc
     3301 caaatcataa tctaaaattt cattgccaat gcctaagatt gcatccctaa atcgaggatt
     3361 ttctttttcc aattctggta agtaagagtt tcgaatacga tttcgaaaat aatgattctc
     3421 ctgatttgat gtatcttcaa agtgaaaaat tgatggaaag tcttttttct gaaaatgcaa
     3481 gaagggacga atgatttcta tctctccgac tacttgcttc tccttaattc ctgatagata
     3541 gcgcaagcga gttcctcgaa tcaagcgcat caaaatcgtt tccacctgat catcagcatg
     3601 gtgggcagtg actaaagctg tcgcacctgt ctttttcatg acctcttgaa aaaaatcata
     3661 acgaaaattt cgtgcacgcg cttctgaaaa ttctcctgaa aaattgctga tataaatagg
     3721 aagctctgct tcagcagcca acttccttaa ttccttttct tcccaatctg attcaattct
     3781 ctgcttatga ttcacatgag ctagaatcaa ttcaatctct aactcttttt gataagtaga
     3841 caatacctta aatagaaaca tggaatctaa tccaccagaa agagctagaa ccgccttagc
     3901 atgctttttg aaatatccct tcttgagaaa atgatttaaa aaatctggtt ccctcatttt
     3961 agaacctcat aaacatcctt ggctatctta gaaatcgtat cataatcaga attcttagtg
     4021 aaaatagaaa gaataaatgg agaatctgca tagacaacac ccgtatcatg cttaaattca
     4081 tccgcatctc caattttatg agctacttta acagaaacac ctttggcaat tcgctgacta
     4141 tcaaaatctg ttttagtcaa agactctaac acaaatccat tttgattata aatagcttcc
     4201 ataaacttcc cggccatctt agaagaaatc aatttttctt ttggatccca atcatctccc
     4261 ataatggcag acatcttgga tttgaatgtg gcatcagatt ggtttgaaat gtaatatccc
     4321 aatagattat gagctacatt atcagattct tttgatactt tcgtaattaa atcctttaaa
     4381 gaatattctt tattatcttc ttttttagga agactaccac ttccctctgg tttataagaa
     4441 cctggaaaat cattgactgc agatacgtat tttacagtcg tatctaactg ataaagaccc
     4501 tcatttattt tttcttgcgt ataatagaga taagagagtt tcaaaacgct ggctgcatac
     4561 atcttttcat cttgattgat accagcttct tttccagtag tcagttgctt aacataaata
     4621 gagaaagaat ctttctgata tttttcagat aacatttctt gaactttact catccgatta
     4681 tcttcttcag aagttgattc tttagctacc catccagcct gatcaatatg tagaaattct
     4741 cttccttcta caaacatggt cttgtcgatt gatacttgcg aataagctga taaggatgat
     4801 ttcacttctt ttaaatcata aggactattg tacagtttaa agtcagattc taaccatgct
     4861 ttttttattg ttggagttac ctctgattga tcatataaaa atcgtttgtc cgcagctata
     4921 aattgatgat ttgatagctt aaatactgga attccttgtt tatttaagcg ccactcggtt
     4981 atttgaaaac ttgttttggg agtcaatttc ccagattcca ctactaaatc ttcattcgca
     5041 taaacaggaa cctctccata aaccatggga gaacttaatt tttctctaaa ataaatacca
     5101 aagtcagatt gtgaaaggta ataaatttct ttcgaagtat agacgacttc tttttctgtg
     5161 ctaacgactt ttgaaatggt caaaaaactt ggtagcaaca aaataattaa gaatttacgc
     5221 attcttcctt tccttttctt cttgtaaacg caataattga tttttatcag ccaattcttc
     5281 cagcttttca tctgacaaac tcaaaaattg ctctattacg tctaataaat tttccatttt
     5341 atcacctttg aagcaagtca ggaatcgtat aaactttttc cctcgactta gaataatagt
     5401 acttcgctcg tgtatatttg gcagcataat cttcatcttt caacttggta gcaaatgctg
     5461 tctccttatc cttttcatca ctcaaagttt gatactgagt ttgcaagtct gctaattgct
     5521 gacgtctttg gagtaattgc tgataactct gcgctaaatt aaaagttggc aagataaata
     5581 atagcataat caaaatcaat acccctccca taaaacgatt ccgtttttgt cgttctttca
     5641 tcaggtagcg acgacgttgg tattcatttt gaataaaaga attattcaat tgtacaatat
     5701 ttttagacat tttcttctac ccgtgtttca ctgataattt catacattcc tgctgcatct
     5761 tctttttttg tactatcttt catctctagt acttttacaa gcagcaactt attgccaaag
     5821 cgaatttcaa cttggtcatt aactttcaag tccgttgaac ttttggccaa gattccatta
     5881 accttgattc tacctttatc tgctacttcc tttgcgactg tacgacgctt gataattcgc
     5941 gatactttta aatatttatc taatctcatc cttattacct caatttatta ttgtaccatt
     6001 tttatctatt ttatagaaga aaaatatcaa atggaatttt cttccttaaa ctcttttatc
     6061 tctaataaac tttctccaaa aatcagcaga ccttctaaaa tttcataatc tttcttattt
     6121 tggacatcaa atacaagctc cattaatccc ttattctcag cgatgcctgc ttttaagttc
     6181 gttacggata aagctttaaa ataatcttga gctaaaaaca atcgttgagt gactttttca
     6241 aattgaattg taattttatt atcttttctt tccacacgtt gaacaaagac cttgtccaag
     6301 tatgatttaa ccaaaccaat ctctaaaaga taggctacta catctgggta ttctccaaaa
     6361 cggtctatca actcctcttg taactcttca taattgacac ggttgtcaat ttgacgaatt
     6421 ttcttgtaaa tttcaatctt atgtcgttga tcagaaatat aagtatcagg aagataggca
     6481 tcaatttgca aaatcaactc agcattccct ttggttcttg tgttagcgtt agcattaccg
     6541 tttcgtttag caatagcttc ctctaataac tgcgaataca attcaaaacc aacagaatca
     6601 atgaaaccag actgggattt tcctaaaaga tttcctgctc cacgaatcga aagatctcgc
     6661 attgcaatct taaagccaga gcccaattct gtaaatcctt taatcgcttc taatctcttt
     6721 tcagagactt cactgattga tttttctgga cgatacatga gataagcata agcaatacga
     6781 ttactacgac cgactcttcc tcttaactga tataaggttg acaagcccat atggtccgca
     6841 ttttcaataa ataaagtatt agcatttgga atgtccaccc ctgtctcaat aatagtagtc
     6901 gtcaccaaga tatcgtattg tccctcaata aagtctaata gagtattttc caactggact
     6961 tcactcattc gaccatgaac atatccaatc gaagcctccg gaatcaactc ctgtaattct
     7021 gaaaccttct gaacaattgt gtcaactttg ttgtaaagat aataaacttg acctccacgc
     7081 tccatttcac gcaagacagc atcacgaatg acactatcat tcttttccaa aacataggtc
     7141 tgaacaggat agcgattagt cggcggagtt tcaataacag ataaatctct gattcccagc
     7201 atagacatat ggagggtacg agggattggc gtagcggtca aggttaggac atccacttgt
     7261 ttcttcagtt ctttcaaagt ttccttatgc ttgacaccaa atcgctgttc ctcatcaata
     7321 atcatcaagc ccaaatcagc aaacacaaca tcttttgaca aaacacgatg tgttccaatc
     7381 aaaatatcga cttgaccgtt tttcaatttt tcaagtgttg cagtctgctc ttttttactt
     7441 ctaaagcgac tcaacacatc aatattaact gcaaaatttt ggaatcgttc cttaaaattc
     7501 gtatagtgct gttgcgctaa aaccgtcgtc ggaactagaa tgacaacctg tttgtgatca
     7561 ttgactgctt taaaggctgc acgcatagca acttcagtct ttccaaaacc aacatcccca
     7621 actaaaagtc gatccattgg ctgagaagcc tgcatatccc tcttgatttc ctcaatacta
     7681 cgaagttgat catccgtttc aacataaggg aaagcatcat caaaggcatc ttgatcatca
     7741 tcatcagctg agaaagcaaa acccttcaac tgactacgtt cagagtagag tttgattaaa
     7801 tcatcagcta tatcctctac ctggttctta accttttgct tggccttttt aaaatgaccg
     7861 tcatttaatt tattgagttt tggagcttta ccatcacttg aaatatattt ggacagtaga
     7921 tgaatctgtt ccacggggat agaaatttga tcaccatttt ggtattggac actgacataa
     7981 tcgcgatgaa ttcccttgat ttcaatggtt tcaattccta gatattgacc aatcccatgg
     8041 atatgatgga caacatagtc ccctttttca agttcattgt aatcttttaa tctctctgca
     8101 tttgaaacat gttgtcttcg aaaacgacgc tttaatttct tttgaaaaat ctcatgttca
     8161 gttatcaata aaatcttttc atctacaaaa tgaaaaccat gtctgagatt accctctatt
     8221 aaatttacag attctttaca gatacttgtc ttatctctag aatccaattt aatctgatat
     8281 tcctctaaca tatcctccaa tgttttactt cccattgaat tgctagactg cagaataatg
     8341 gtgtaatcca tttttttata tcgttcaatt tcttctttta gaaaagaaaa ctgattgaaa
     8401 aattcctgta taggatattg attgaattga taaattttgt caaatttgag atttcctaaa
     8461 cccttttgaa gattagagaa aaaggtcact ggactttgtt ttttatagat ttgttcaata
     8521 tcagaaaaat actgcatatc agaaaatgct ttactattct gtaattcttc tgtaaagtac
     8581 tgcgctaatt ctctttcaaa gacttcatac tgattcatca atttttgata atcatcaaag
     8641 aatattggag tatctttttc aatataatca aagacagtcc atgtcttatc atagcacaaa
     8701 gataaaaact tccgagaatc tgcatgactt tgtttttggt gaaaacttga aagaatttct
     8761 tctaggtatg atttcaaaat aggtgataaa gtttttgaaa tttgtttttc taaagctgac
     8821 tgtcctcgtt gataatcctt ttctctcaaa agcatatcac tagctggaaa gatagtgagt
     8881 tctgtcttat tttctttcga taattgtgtt tctacttcaa atgacctgat accatcaatt
     8941 tcatcaccaa aaaactcaat tcgacaaggt tctaactggg atatttcaaa aatatctaaa
     9001 atatctcctc gaagactaaa ttcgccctga gtttgtactt gagtaacttt ttgatagcca
     9061 ttttccttta actgatggat aaacgcgtgt tgagcatatt cttcaccaac tgagattttt
     9121 acaatactat ctttgaatgc attgggagac ggtaaaatca atcgacttgc tgcgatatta
     9181 caaactaaaa tccctttctt agatgaatca gtcaaaaaac gcaaggcttc aacccgtgaa
     9241 ataatttttt cctgtgaaga catcaaaaac tccaccatag gagcatcatc taccaaaaat
     9301 ggatagacga gttcctcacc caagatagaa ataagatcac taacaagtcc ttctgcttct
     9361 ccataagttg acgtcaataa cacaatccta tcttcttttt ctaaactgct tgcaattgca
     9421 agagccttag tagatgttga taaaccaagt attagttgtc ttttcttatc tgttaaattt
     9481 tgatgccatt ttttaatctg atcattttct gagaataaat ctaataaggt caccatttat
     9541 ccgttatacc tctgcattgt tttctcaaaa tttttctctt gtaaatagta ttttacagaa
     9601 tcgtcaactt tgtcaacaga ctgtaaaata ccgatataat catccctgtc aaacttactc
     9661 aaaacatgat gaacaactga cataccattt ttaggtcttc caattccaat cttaacacgg
     9721 ttaaagacct gagttcctat atgttgaata atagacttga taccattatg accacctgct
     9781 gagccttttg ctcttaaacg aattttccca acttccatgt caagatcatc gtaaatgata
     9841 agtaaatcgt caatatccaa accatagtaa gttaataaag catgaactgc ttttccactt
     9901 tcattcataa aggtcgttgg tttaaccaga taaatttttt ctccatttag gaaaaaggat
     9961 gctaggtcag cttgaaatat cttatcgtgt gtaaaagtga cattctgttt cttcgctagt
    10021 tgatcaatca acataaaacc aacattgtgt tttgtttcaa aatatttatc ccctggattt
    10081 cccaaaccta caagtaattt ggtcatttat ttttcctttc aaaagccaaa agggttggaa
    10141 tttttttcca acctaattga caccatttat taatttttag acattaaagc ggaattctat
    10201 gatgtcgcca tcttgaacga tatattcttt tccttcttca cgcaagcgtc cagcttcttt
    10261 tacggccttt tcagatccgt atttcactag atcttcatat gacatggtta ctgcacgaat
    10321 aaagcctttt tcaaagtctg agtggataat accagctgct tgaggagcct tcataccacg
    10381 tttgaaagtc caagcgcgaa cttctttttc accagctgtg aagtaagttc ccaatccaag
    10441 caagtggtaa gctgcacgcg tcaacttatc tacacctgat tctgtcaaac caatggcttc
    10501 aagaaactct tttttatctt catcatccaa ttcagaaatt tcttcctcag cacgcgcaga
    10561 aataacgact acttcagcat tttctgtcgc tgcaaattca cgaatttgtt tgacatagtc
    10621 gatagagtca ggttctgaaa ccacatcctc gtccacatta gctacataaa gaactggttt
    10681 agtcgtcaaa aggaaaagac ctttgacaac cttttgttcc tcatctgtaa attcaatggt
    10741 acgagctgat ttcccgtctt ctaggactgg tttaatcttt tgaagaacat tgaattctgc
    10801 tactgattct ttatcttttt gcgtacgtgc catcttttct acacgcgcat atcgtttgtt
    10861 cactgattct aagtcagcaa gaattaattc cagattaatt gtatcaatat ctgcaagtgg
    10921 atctacaaag gcgtcttcac gtccttgctc gcgcatcaca ttttcatcat caaaagcacg
    10981 aactacgtga acaatcgcat ctacttcacg aatattggcc aagaatttat tccctagccc
    11041 ttctcctttt gaagctcctt ttacaatccc tgcaatatcc gtaaattcaa atgttgtggg
    11101 aactgtcttt ttaggagtta tcatttcagt tagtttttgt aggcgttcat ctggaacttc
    11161 caccattcca acatttggat caatcgtcgc aaatgggtag tttgctgcct ctgctcctgc
    11221 ttttgtaatt gcattaaata gtgttgattt accaacgttt ggcaaaccaa cgatacctgc
    11281 tgtcaaagcc atatttctca ttctccgttt tcatttcaat ccctaatatt ataacacaaa
    11341 aagggataaa gtgctaaccc tctaactaag ggttctcagt caataatttt attcattttt
    11401 cgctcaaaat catatcgccc catcatgaca acatgctcac aattactgca ttttattttg
    11461 atatctgctc ctacacgtgt aatttcccaa cgattagcct ttttaccagt cgacttgatt
    11521 gtacaagcgt gtgatttttt catctcaaca aaatttccaa cttgatacat actactctcc
    11581 ttttcttttt cgattatatc ataaaagagg cgagccaggc tcaacctctt tcacttaatt
    11641 tgtacgaact ggtgtaatga gctgcatgaa gtcttcgtca gtatctgctg gcacaagagt
    11701 aaatggacga acagctgaga taaagctaat ggtcaccttt tcgctattta aagctttaag
    11761 agaatcaatc aagtaagttg ggttgaaact aatggtcaaa tcttcaccag taacctgatc
    11821 agtatcgatt tcttcgttta ctttaccaac ttctggagag tgaacatggg cgctaacaac
    11881 cccatcctta atttcaagtt tcacagtacc attttgagtc gcacttgata aaagacgggc
    11941 acgctccatt gactggcgta agtttaccac attaaaagta atagtagtgt taaagtctgt
    12001 tggaatcaag cgatctgtat caggatagtt tccttctagg agacgagtat agaagctaat
    12061 attttcgctt ctaaagagga tttggttatt ggcaaagaaa atctctacag tttcgatatc
    12121 atctgtaaat accgctgaaa attcgcgtag agaacggcta ggaattacga catcaaaatc
    12181 atcactattt ttttcaagag tcaatttttt ctggcttagg cgatgagagt ctgttgcaac
    12241 tgtttttaac tctttgtgtt gactcaatac gaagtggaca cctgttaaaa tcggacgact
    12301 ctcttgtgta cttgcagcaa aggctgtttc attaataatt ttcttgagta attttgtttc
    12361 aagtattaaa ggagtgcttg ctgaaatttc ttggattcgt ggatattgtt cgctatcttt
    12421 tccttttagg gtaatttctg atttgccact ggttaaaaca atttgatttt gttcaatttc
    12481 tttaaaatca agagttacat caggtaaact agatactaca ttgataaaga aagaagcttc
    12541 aagaaggatc gaacctaaag aagtaattaa caaaccagca tcttcatttt tttgagaaat
    12601 aaaattttca attgaaattt gaccatttga accaattaaa gtaatacctt cattggtcac
    12661 gtcaattttt actgttgata aaataggaat ggcattttta gaactaatag ctctcttagt
    12721 agtatttaat gcttgtagaa ataaattttt attaattgaa aaatgaatca tggattctcc
    12781 tttatttatt tttagtatta gaaagataat agtaataata gagtctgtga aatctgtgga
    12841 aaacagcctt taaacaagtc atatcaagtt ttttagcttg tttaaaaaat gtggataaaa
    12901 aagataaaaa actaaaagtt atccacaaat tatttgattt tctttttgat tgattcaatt
    12961 tctaaacgta aattatcgtc ttgatcaatc aaagatttta ttttggcatg ggcatgaatg
    13021 actgtggtat gatcttttcc cccaaattcc ttcccaattt ttggaagact attatctgtt
    13081 agttctctag ataaatacat ggctacttga cgggccaaaa caatattttg aaggcgtcta
    13141 cttcccttca tttctttgat actaacacca taaaagttac caacttcagt ttggatttta
    13201 tcaattggga tgacgagcat ttggctaaca tcttgtttgc gggctctaat ggcttctgca
    13261 gcaatatcaa tagtgatatc cttgattttt tttactctgg caattaaagt gatgtcgttg
    13321 atggctccct caagatctcg aacatttgaa tcaaattgcc cagctaggta ttctagagta
    13381 tcactttgga aattgtagcc taaatgttcc gttttacttt gtaaaatggc aatacgtgtt
    13441 tcaaagtcag ggggtgtgat agtttgtgtc aatccccaac taaaacgcgt gacaagcctc
    13501 tcctcgagcc cttctagatg ttttggacta cgatcactcg ttaggacaat ctgtttttgc
    13561 ttgtcatgaa gggcgttaaa ggtattgaaa aattcttcct gagttgcgac tttttttccg
    13621 ctgagtgact ggatatcatc gattaacaaa agatcaagac tacgataggt ctttttaaac
    13681 ttttccattt ccccaagtct taggtgatca agaaagtcat taataaagct ttcggcaggg
    13741 atatatttaa cacgcgcatt aggaatattt tttagaattt catttccaat agcgtttaat
    13801 aagtgagtct taccaaggcc tggtcctcca tagataaaaa gagggttata ggtcagagcc
    13861 aaatcttcag agacagctaa agcggctgac acagcccaaa catttccatc cccttgaata
    13921 aagttatcaa aggtatactt ttcttttaat cccgtatctg aataaggaat agatactaac
    13981 tttggactat agttataaag agttaaattt gtagcttctt caacttgtga gctagtcgta
    14041 tcttgaggtt tggtgaaaat atagtgggga gttatttcag cgtcataaat ttcaaaacca
    14101 gctactacaa taatatcttt tagttgtttt tcccagacca tttccatttc agagcgaggt
    14161 agaaatatag tggcaacatt ttcctctacc ttgatgagtt cagcttgaat agcatagaaa
    14221 tcatacatgg atcgagtcag tctttcttgt gcaaattcta atatacgatt ccaaaattgt
    14281 ttttctttca atcctttctc ctcctttact atttaaaagt ttaatactag agatatttta
    14341 ccatagatag caagaatttt ccacaagctg tgaaaaataa tccacaatgt taccaaactt
    14401 tatccacagg ttggggataa aagaagaaat tattgattta ttaagctttt tattgaaaaa
    14461 catagtggat aaccttgtga gataaaaaaa taaaagaaca gccttatttc aggctgttga
    14521 taattctact atattcttct tgatttgaaa aagaaataat gatttttcca ctgtcttttt
    14581 tagatagttt aatttctaca tctaatccga gtagttttct taactgtttt tcttcatttt
    14641 gtatgaaatg attagttttt tgctgtttct tttgtttttt ctctgtcaga agagcttcta
    14701 atttccttac agaaatatct tcttctataa tccgttgaaa gaaatagtct tgttgttcct
    14761 tatttaaccc aactagggaa cgcgcatggg cttgtgatag tttgccattt tctacttctg
    14821 aaagaatctg ttctggcaag gaaagtaaac gaatggagtt gctgatatat ggacgagact
    14881 tgcccatctt atctgcaatt tcagcatggg tgaatccttt ctctacgaga gattcatagg
    14941 cgcgtgcttc ttctattggg tttaaatttt ctctctgtaa attttcaata atggactgga
    15001 ccatcatctc ttggtctgaa atctgtttaa caacagctgg gatagaccgt agaccagcta
    15061 aaagtgaagc ccgatagcgt ctctctcctg caaggatttc ataaccaata acaggagatt
    15121 gacgaacaat aatcggttga atgaccccat tttctttgat agactgtgct agttcatcta
    15181 gtttttctct atcaaattct tttcggggtt gatagggatt tttttgtata tctgtgatag
    15241 aaatcatttc aaatttttcc atgattctac actaacacat cttttctctt atgtaaagct
    15301 ttctttacat agatgtcaat taagattcta aatcacctga actcttgtta agtttgatag
    15361 aggtagtttc ttctttcccg ttacgatagt aggttatctt aatggtgtct ccgatagaat
    15421 ggttgtaaag agcactttgt aagtctgttg atgaagcaat ctctttgtca tctacttttg
    15481 taattacatc gtatttttca aggtgaccat tggcaggcat attactttgt accgaacgaa
    15541 caactacacc agatgtaaca ttacttggaa tattgagtct tctgatgtcg cttgtactca
    15601 cattagataa attaaccatc tggattccca aagctggacg cgtcactttt ccgttttttt
    15661 ctaactgttc aataatattg atagcatcat ttgcaggaat tgcgaaacca agaccttcta
    15721 cagatgttcc tccatttgta gcaattttac ttgaggtaat tccgataacc tgcccttgaa
    15781 tattgatcag tgggccgcca gagttacctg ggttaatagc agtatcagtt tggatggctt
    15841 ttgtagaaat agcttgtcca tcttccgatt ttaaggatac atttctattg agactggata
    15901 cgataccttg agtgacagta tttgcatatt cagaacctaa cgggctaccg atggcaatag
    15961 cagtttctcc tacagttaac ttactagaat caccaaactc agctactgtt gtcacttttt
    16021 ctgaagagat ttttacgaca gcaatatcag agaaagtgtc agctccgaca atttctccag
    16081 gtactttagt cccatctgac aatcgaatat ctactttgct ggcgccattt ataacgtgat
    16141 tgttggtgac gatgtaagct tctttatcat tctttttata aataactcca gatccttcac
    16201 tagagattcg ctgagaatct gtgtcagtat catcattgcc aaatacgcta ttttgtctgt
    16261 ttgccgaata agtaataaca gaaacaacag catcttttac tttgttaaca gcctgtgttg
    16321 ttgaattttc gttcttatag gcagtttgtg taatagtact attgttgtta gagttgttta
    16381 cactactttt ttgagttagt tgagttattg aaaaactacc caaggctcca ctaaaaaagc
    16441 taatgacgat aacgactaat aattgaaacc attttttgta aaatgttttt agatgtttca
    16501 tatttgcctc catatgtttg aattactgaa agtataaact gactagctta attataactt
    16561 aaacacaaaa gttttacaca aactgtggat aactcttttg aaactgtgat tttcttaatt
    16621 gaaatctatt ttttattttg tgaataagat gtgaaaaaat agagaatatg ttagaataga
    16681 gtcatgaaaa ttaaagttgt aacagttggg aaactgaaag aaaagtattt aaaagatggt
    16741 atcgcagagt attcaaaacg aatttctaga tttgctaagt ttgaaatgat tgagttatca
    16801 gatgaaaaaa caccagataa ggccagtgaa tcagaaaatc aaaagatttt agaaatagaa
    16861 ggtcagagaa ttttatcaaa aattgctgac cgtgatttcg ttattgtgtt agccattgaa
    16921 gggaaaactt tcttctcaga agaatttagt aagcagttag aagaaacttc tataaaagga
    16981 ttttctactc ttacttttat tattggggga agtttaggat tgtcatcatc tgtaaaaaat
    17041 agagccaatc tttctgtcag ttttggtcgc ctaaccttac cccatcagtt aatgagacta
    17101 gttcttgttg aacaaatcta tcgcgctttt acgattcagc agggattccc ctaccataaa
    17161 tagaaaattg acttttaatt gaatttttgg tagaataatt gtattaggtc tcatagctca
    17221 gctggataga gcattcgcct tctaagcgaa cggtcgcagg ttcgaatcct gctgggatca
    17281 atataatagc aaagctggga attttcccgg cttttttctt aaaaaagtac actttgggag
    17341 aaaaaaatga cagttgagag aattttatct aaaacgaaat tccattttgt ataatggttt
    17401 ttgtaagtta gcttacaaga aaaaacattt taggagattt tattatgaaa aacacagtta
    17461 aattggaaca gtttgtagct ttgaaggaaa aagacttaca aaagattaaa ggtggggaga
    17521 tgaggttgtc aaaattcttc cgtgatttta ttttacaaag aaaaaagtaa tgaaataagg
    17581 ggaaagagta atggatttat ttggatttgg gacggttatt gttcattttt taattattag
    17641 tcacagttac cattttattt gtaaaggtca aataaataga aaagaattat tcgtttttgg
    17701 tgcttataca ttactaacag aaatagtatt tgattttccc ttatatattc tatatttaga
    17761 tgggttaggg attgaaagat ttttatttcc tttgggatta tattcctatt ttcgatggat
    17821 gaaacagtat gagagggata gaggactatt cctaagttta ctactatctc ttttatatga
    17881 gagcactcat aactttctgt ccgtaacttt ctcctctata acaggagata attttgtttt
    17941 acaatatcat ttcccattct ttttcgttgt gacggtgtta acctattttg ttacattaaa
    18001 aatcatttac tatttccatt tggaactagc ctattttgac gaggactacc tttatccttt
    18061 cttgaaaaaa gtattttttg ctttactatt gctacatatt gtatctttcg tttcagatat
    18121 ggtaagtacg attaaacatt tgaatagttt tggaagtatt ttgtcatcta ttgtctttat
    18181 ctctctcctt ttgaccttct ttgcaatgaa ttctcataaa gttcaaatgg agaaagagat
    18241 tgctttgaag cagaagaaat ttgaacagaa acatttacag aattacacag atgaaattgt
    18301 tggtctgtat aatgaaatcc gtggttttcg acatgattat gctggaatgc ttgtcagcat
    18361 gcagatggca attgacagtg gtaatttaca ggaaattgac agaatttaca atgaagtttt
    18421 agtcaaagca aatcataaat tgcgttcaga taagtacact tactttgatt tgaacaacat
    18481 agaagactca gctttacgaa gtttggttgc tcagtcaatt gtctatgctc gaaataatgg
    18541 tgtagagttt acactggaag taaaagatac gattaccaag cttccaattg aactattgga
    18601 tttggttcgt atcatgagcg ttttattgaa taatgctgtc gaaggatcgg ctgatagcta
    18661 taaaaagcag atggaagtag cagttattaa gatggaaact gaaacagtta ttgtgattca
    18721 gaattcatgt aaaatgacga tgactccttc aggagatcta tttgccttag gattctccac
    18781 taagggaaga aatcgcggag tcggattaaa taatgtgaaa gaactactag ataagtacaa
    18841 caatattatt ttagaaacag agatggaagg cagtacattt agacaaatca ttagatttaa
    18901 gagggaattt gaatgaaagt tttaatttta gaagatgtta ttgaacatca agtgagacta
    18961 gagagaatat tggatgaaat ttcgaaagaa tcgaatattc caatatcata caagacaacg
    19021 ggaaaagtcc gtgaatttga agaatacatt gaaaatgatg aagtaaatca gctttatttc
    19081 ctagatatcg atattcatgg aattgagaaa aagggatttg aagtggctca gctcattcgt
    19141 cattacaatc cttacgctat tatcgtcttt atcactagtc gatcagagtt tgcgactcta
    19201 acctataaat accaggtatc agccctagat tttgttgata aggatatcaa tgatgagatg
    19261 tttaagaaga gaattgagca aaatatcttc tacacgaaga gtatgttact tgaaaatgaa
    19321 gatgttgtag attatttcga ctacaattac aagggaaatg atttaaaaat tccttaccat
    19381 gatattttgt atattgaaac aacaggggtc tctcataaat tgcgcattat tggtaagaat
    19441 tttgcaaaag agttttatgg taccatgaca gatattcagg aaaaggacaa acatactcag
    19501 cgattttatt ctcctcacaa gtcatttttg gtaaatatag gcaatatcag agaaattgat
    19561 cgaaaaaact tagaaattgt tttctatgaa gaccatcgtt gtcctatttc aagattaaaa
    19621 attagaaaat taaaagatat tttagagaaa aaatctcaaa agtgattgac aattagcaag
    19681 aaattgatat aatggttata tctgctacag atagaaggtc cgttggtcaa ggggttaaga
    19741 caccgccttt tcacggcggt aacacgggtt cgaatcccgt acggactatt ttatccgcca
    19801 tagctcagtt ggtagtagcg catgactgtt aatcatgatg tcgtaggttc gagtcctact
    19861 ggcggagtat agataaaagg gaacacagct gtgttcctct ttttgtatca atttgtatca
    19921 ccaagcattt tcataaggaa gtctgttatt tcttgagaac tttctttttt tccatgtgca
    19981 atccaagttt ggcagacacc aaaaagtgca tgagttagat agatgctact atattctaat
    20041 tcggtggtat ttagattcag ttgcataaat cgcttttgta aatctgtact aagcatgata
    20101 tgaagtttat ttcgtaagaa attttggatt tctttagtcc cattttcaga aagaagggca
    20161 gccagaagtg gttctgactc tagatattca aaaacttcta aaatagcgtc tcttttgtga
    20221 tgagcatgtt tttgaaaaat atattcaaat gtatggaata gcttgctttg atagtgctca
    20281 atcatatcat acttatcctt atagtgagta tagaagctgg aacgactaat tccggctttt
    20341 tctactaatt tgacagtaga aattttatca aatggctgtt ccatcagtaa ttgtaccata
    20401 gcattttcaa tagttcgctt tgtttttaag cgtttgttac tttcttgcat atttcctcct
    20461 tgtaaacaaa ttagactata tgtttaaaaa tagatttttt atcttgtaat ttagattttt
    20521 taatgtataa tctattatat caaaatttta gacaatatgt ttaaaaaagg agaaactaag
    20581 tttaaagaat ggaaagcaat ttaaaaaaaa ccaaccttta ttattgtcat gatcgggatt
    20641 tctcttattc cagatctgta caatatcata tttttgtcat caatgtggga tccatatggg
    20701 caattgtctg acttacctgt ggcagttgta aataatgata aagaggcttc ctataatggt
    20761 aatactatgg caataggaaa agacatggtg tccaatttaa aagaaaataa aaccttggat
    20821 tttcattttg tagatgaaga ggaaggaaag aagggattgg aagatggcga ttactatatg
    20881 gtagtgactt taccaagtga tttatctgaa aaaacaacta cattatccaa tattcaatcg
    20941 acagcagctt atcaatcatt gacaagtgag caacaaactg agataagtga ttctgtatct
    21001 caaaattcaa ctgatagtat tcaatcggct cagtcaattg tagctttagt acaagattta
    21061 cagggaagtt tagaaaactt acaaaatcaa tcttctaatc tttcgacttt aaaaaatcaa
    21121 tctaatcaag tatcacctat tacttctact tctttgatag gattgtcaag tggattaaca
    21181 gagatacaag gagatgttac tagcaaatta gttcctgcca gtcagtcgat tgcatcaggt
    21241 gtaaacgcat atactacagg tgttgataaa gtttctcagg gcgcaagtca actaagtgaa
    21301 aaaaatgcca ccttgacagg tagtttggat aaactagttt caggctcaaa caccttgaca
    21361 caaaaatctt ctagattgac agcaggagtt ggttaattac aatcaggatc tgggcaatta
    21421 gcagacaaat ccagtcagtt actttcaggt gcttctccat tagagaatag agctaataaa
    21481 ttggcagatg gatctgggaa actagcagaa ggtggaacaa agttaacttc tggattggaa
    21541 gatttacaga caggacttgc ttctttagga caaggactag gtaatgctag tgatcaactc
    21601 aaatcagtat caacagaatc taaaaatgca gagattttgt caaatccact caatctttca
    21661 aaaacagaca atgatcaagt tcctgtaaat ggaatcgcaa tagctcctta tatgatatca
    21721 gttgctcttt ttgttgcagc aatatcaaca aatatgatat ttgcgaaatt gccttcagga
    21781 cgtcatccag agagccgttg ggcttggttg aaatctcgag ctgaaataaa tggtattata
    21841 gctgttttgg caggaatttt ggtatatgga ggagttcagc ttattggttt aactgctaat
    21901 catgagatga gaatatttat tctcatcatc ctaacaagtt tagtattcat gtctatggtg
    21961 accactttaa caacgtggaa tagccgtata ggagcttttt tcttacttat tttgctttta
    22021 ctacagttag catcaagtgc aggtacttat ccacttgctt tgacaaatga tttctttaga
    22081 tctattaatc cctggttacc aatgagctat tcagtttcgg gattacgaca aacaatctct
    22141 atcaacaagt cattttccta gctgtcatac tagctctatt tactggttta ggtatgctag
    22201 cctatcaaca taagaaaatg gaagaagatt aaaaaaatcg accgattaat gaactgcacc
    22261 ccaaaagtta gacagaaaaa atctaacttt tgaggtgttt tattatgaaa ttaa
//
LOCUS       DAVBIC010000038        22017 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.038, whole genome shotgun sequence.
ACCESSION   DAVBIC010000038 DAVBIC010000000
VERSION     DAVBIC010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22017)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22017)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22017
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.038"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            51..233
                     /locus_tag="VQ664_001448"
     CDS             51..233
                     /locus_tag="VQ664_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000842022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HET2789598.1"
                     /translation="MKSQKIKVSFTQSKIVTPILLVNKTIVWYGAMPLLGKVDEMTIL
                     RLESASIVSELVAGLR"
     gene            533..1372
                     /locus_tag="VQ664_001449"
     CDS             533..1372
                     /locus_tag="VQ664_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HET2789599.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKTGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELVYITEKIINLGKITLGNNFDEIIYINLTDHIS
                     SSIERYKEGIIISNPLRWEISKYYKEEFELGKRALQIIKKELGIELPIDEAAFIALHF
                     VNANLENNFQESYKITEIIMGIEKIIQDFYCTEFNQDSIDYYRFITHIKLFAHRLVEN
                     TTYCDDDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLLTSSELVYLMAHIRRLTK
                     NLD"
     gene            1390..3228
                     /locus_tag="VQ664_001450"
     CDS             1390..3228
                     /locus_tag="VQ664_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HET2789600.1"
                     /translation="MSYKDTVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPDVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGAPVTPASYGSSVVPILIMV
                     WLMKYIEKIIAKLTPAITKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     GVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVKAGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     NLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            3241..4656
                     /locus_tag="VQ664_001451"
     CDS             3241..4656
                     /locus_tag="VQ664_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HET2789601.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLIGIDFYHKYKEDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWIDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEN
                     DINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSAIPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDELNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGNGTFNRY
                     KKMSFTWYKGVIESNGESLFK"
     gene            5248..6294
                     /gene="pheS"
                     /locus_tag="VQ664_001452"
     CDS             5248..6294
                     /gene="pheS"
                     /locus_tag="VQ664_001452"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HET2789602.1"
                     /translation="MSTIEEQLKALREETLASLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
     gene            6294..6803
                     /locus_tag="VQ664_001453"
     CDS             6294..6803
                     /locus_tag="VQ664_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2789603.1"
                     /translation="MIRKVEMADVEVLAKIAKQAFRETFAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GLGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            6880..9285
                     /locus_tag="VQ664_001454"
     CDS             6880..9285
                     /locus_tag="VQ664_001454"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HET2789604.1"
                     /translation="MLVSYKWLKELVGIDVPSQELAEKMSTTGIEVEGVESPAAGLSK
                     IVVGEILSCEDVPETHLHVCQVNVGEEEERQIVCGAPNVRAGIKVMVALPGARIADNY
                     KIKKGKIRGLESLGMICSLGELGISDSVVPKKFADGIQILPENAVPGEEVFSYLDLDD
                     EIIELSITPNRADALSMRGVAHEVAAIYDKAVNFKEFTLTETNEAATDALSVGIETDK
                     APYYAARILDNVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDT
                     FEGTDIRVREARAGEKLVTLDGEERDLDVNDLVITVADKPVALAGVMGGQATEISEKS
                     SHVVLEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAAASLIAELAGA
                     TVRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFT
                     VSVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTVTQKLRRQVRTIAE
                     GAGLTEIITYVLTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNV
                     ARKNKNLALYEIGKVFEQTGNPKEELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYA
                     KGILEALFTRLGLEVTYTATAEIASLHPGRTAVISLGDQVLGFLGQVHPVTAKAYDIP
                     ETYVAELNLSVIEAALQPAAPFVEITKFPAVSRDVALLLKAAVTHQEVIDAIQAAGVK
                     RLTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEKKVNA
                     EVR"
     gene            complement(9458..10459)
                     /locus_tag="VQ664_001455"
     CDS             complement(9458..10459)
                     /locus_tag="VQ664_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HET2789605.1"
                     /translation="MIKTFLSALSVILFVIPIITYSFFPSSNLNIWLSTRPILAQIYA
                     FPLATATMAAILSFVFFSLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTNSGIAPVTVIVKKSYGFYTEAKTFHTTRFGTIVLHSRKQNIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIADDFNATMRHGALAKISSHRDAL
                     NVLPPFERGTWNSQSPKLFNATIDHILLPKNHYYVKDLDIVSFQNSDHRCIFTEITF"
     gene            10615..11103
                     /locus_tag="VQ664_001456"
                     /pseudo
     CDS             10615..11103
                     /locus_tag="VQ664_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            11187..11453
                     /locus_tag="VQ664_001457"
     CDS             11187..11453
                     /locus_tag="VQ664_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2789606.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMSELIEARYEQGISQKKLEEV
                     SGVSQPVIARMETGESSLQLDTVLKVLTSLGKTLAVVPLEQGKS"
     gene            11714..13963
                     /gene="metE"
                     /locus_tag="VQ664_001458"
     CDS             11714..13963
                     /gene="metE"
                     /locus_tag="VQ664_001458"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HET2789607.1"
                     /translation="MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSLVAAYQEVFAKLAELGATRIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLLQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYVGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAG
                     LTDADYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVASDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            14027..14893
                     /gene="metF"
                     /locus_tag="VQ664_001459"
     CDS             14027..14893
                     /gene="metF"
                     /locus_tag="VQ664_001459"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HET2789608.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNGNIISALQDMQELAPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            15578..17791
                     /gene="pnp"
                     /locus_tag="VQ664_001460"
     CDS             15578..17791
                     /gene="pnp"
                     /locus_tag="VQ664_001460"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HET2789609.1"
                     /translation="MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDDQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELIAFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQAVKDQVT
                     AVYEEKYADHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRLELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHHKDHKPKKEFTETPKDSE"
     gene            17807..18424
                     /gene="cysE"
                     /locus_tag="VQ664_001461"
     CDS             17807..18424
                     /gene="cysE"
                     /locus_tag="VQ664_001461"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HET2789610.1"
                     /translation="MGWWRETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFIW
                     KHGFKLLARMHSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHRSSGL"
     gene            18436..19320
                     /locus_tag="VQ664_001462"
     CDS             18436..19320
                     /locus_tag="VQ664_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2789611.1"
                     /translation="MIQVRNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGELVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFERETASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYPLANVSHIEVLLADSSY
                     QDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRLYILLKDGQVIGTCTVDLSTNT
                     NYFYGLAISEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            19402..20745
                     /locus_tag="VQ664_001463"
     CDS             19402..20745
                     /locus_tag="VQ664_001463"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HET2789612.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYEVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEGLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLELGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMAKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFATADQIRDQLVTQGIKLLDTKDGVRWTRD"
     gene            20738..21124
                     /locus_tag="VQ664_001464"
     CDS             20738..21124
                     /locus_tag="VQ664_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HET2789613.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLISLMLEEQILTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            21128..22012
                     /locus_tag="VQ664_001465"
     CDS             21128..22012
                     /locus_tag="VQ664_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HET2789614.1"
                     /translation="MRAKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLASW
                     LDMMRTLFPNCQTVLQVGAQDYVFVLQQDKYTSVRDILSDMIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
BASE COUNT         6764 a         3965 c         4861 g         6427 t
ORIGIN      
        1 accccaaaag ttagattttt tctgtctaac ttttggggtg tagttcacag ttgaagagcc
       61 agaaaattaa agtgtctttt actcaatcaa aaatagtaac gcctattctt ttggtgaata
      121 agactattgt ttggtatggt gcaatgccat tattagggaa ggtagatgag atgaccatat
      181 tacgtttgga atcagctagt atagtttctg aactagtggc aggtttacga tagagaaaat
      241 ttttaaaaat ttctatgtat gattttcatt tctttagtga gactgttgcc attatcacat
      301 tcgaatcaca caaaataaaa aaatttctac aagtacttga caaatagatt gaaatatcat
      361 aaaatgaaaa tggttacaga gttattaatt atttaagctt catgtcacca ttaaaaattg
      421 aaataaaagg atgttatcac taatacaagt gagcaggaac ctatttaatc acatcggaag
      481 aagtttcttg atgtttttaa gtaggttcct tttattttaa aagggaaatt ttatgatcat
      541 aaaacgaata ctaaaccaca atgccgtaat tgcgcaaagt aaaaaagata tcgatattct
      601 tctttttgga aggggcatag cttttggaag aaaaactgga gataaagtaa atccaattga
      661 tattgagaaa agtttttttc tcaaaaatag agataatatg acccgtttta cagagatgtt
      721 tattaacgtt cctttggagt tggtgtacat caccgaaaaa ataattaacc taggtaaaat
      781 aacattgggt aataattttg atgaaattat ctatattaat ttaacggatc atatttcttc
      841 gagcatagaa cgttataaag aagggattat tatttcgaat cccctacgct gggaaatatc
      901 gaaatattat aaagaagaat ttgaacttgg gaaaagggct ttacaaataa taaaaaaaga
      961 gttaggtatt gaacttccaa ttgacgaagc tgcattcata gcgctacatt ttgttaatgc
     1021 taatttagaa aataattttc aagagtcgta taaaatcact gaaataatta tgggaattga
     1081 gaaaatcatt caagatttct attgtactga gtttaaccaa gattctattg attattatag
     1141 attcataact catataaaat tatttgctca tcgcttggtt gaaaatacaa cttattgtga
     1201 cgatgatgat gaagacttgt tagcattaat gaaaaataaa tatcctagag aatatgaatg
     1261 tggtgaacag gtggcaatgt ttatacaaac tgagtacaat tatttgctga cttctagtga
     1321 attagtttat ttgatggctc atattcgtcg cttaacaaaa aatttagatt aatagaatag
     1381 gagaatacca tgagttataa agatacggta caaaaaatcc tcgatgtaat tggaggtgaa
     1441 aaaaatgtca atagagttac ccattgtgta acacgtttaa gattagaatt aaaagatgaa
     1501 aatttagtca atgatgatga tgtgaagaag ataccagatg taataggtat tatgaaaaag
     1561 aatggacaat atcaaattat acttggtaat gatgtagcta attattataa agaattcgtt
     1621 aaacttggca attttgaatc cgattcagtt gttcaagggc acaaagggaa tattttagaa
     1681 agaatcattg agtatatcgc tggttccatg actccaatca ttccagcaat gttaggggga
     1741 ggtatgttga aagtcttggt aatcatttta ccaatgcttg gtatattgca atcagattct
     1801 cagactattg cttttttgac attttttggg gatgctccat attatttctt accgctgtta
     1861 ttagcttatt ctgcatcaca aaaattaaaa gtaacatcta cattagctat gtctgtagca
     1921 ggtgtacttc tccatccaaa ttttgttcaa atggtgcaat cagggaatcc tcttagttta
     1981 tttggtgcac ctgtgacacc agctagttat ggttcatcag tcgttccaat tcttattatg
     2041 gtttggttga tgaaatatat tgaaaaaata attgctaaat taacaccagc tattactaag
     2101 agttttttgc aacctacgct agtattatta gtatcaagct gtattgcctt agttgtagtc
     2161 ggacctattg gagtaattgt tggtgaagga ttatcaaatc tagttgggca aatgtatggt
     2221 gtagctggat ggcttacatt agctattctt ggtgctatta tgccatttat tgttatgact
     2281 ggaatgcatt gggcttttgc acctattttt ttggcggcat ctattgctac tccagacgta
     2341 ttaattcttc cagcaatgtt agggtcaaac ttagctcaag gggctgcttc gatggctgtt
     2401 gcattaaaga gtaaaaataa taatacaaaa caaattgctt ttgcagcagg tttctcagcc
     2461 ttacttgcag ggattaccga acctgcatta tatggtgtga ctttaaaata taaaaaaccg
     2521 ctttatgcag ctatgattgg tggtggatta gcgggattat ttgcaggtct tactagtgtt
     2581 aaagcatatc tatttgctgt cccatctttg atagcgttgc ctcaatttat ttattctgat
     2641 gtgccatcaa atattgtaaa tgctttaatt gtggcggtca tttcggttgt tattaccttt
     2701 gtattagctt atatatttgg aatcgatgaa gaagagagtt ctagcaattt agaagttaaa
     2761 gctggagttt caaataaaaa aatgatattt tctcctatat caggagaaat cattccgtta
     2821 agcgatgtcc aggataaaac attttcagat aaattaattg gagacggagt agcgattatc
     2881 ccaagtgaag gtaaggttta tgcaccattt gatgggaaaa ttacaaatat ttttccgact
     2941 aagcacgcaa ttggattgaa gagtgatgag ggtgttgagt tactaattca tattggatta
     3001 gatactgttg agctaaaagg tcaaggtttt attagtcatg tagaagaagg agacagagtt
     3061 ttcaaaaatc agttgatttt tgaaatgaac ttgaatttaa tcaagactaa aggctacgaa
     3121 acagttacac cagtaattgt aacgaatacc aatgattttc tagatgtatt agtattacct
     3181 aataatcaga caatcgagca ttctaaggaa ttactggtaa tattataatg gaggaaagtt
     3241 atgaccattt ttccagatga ttttctttgg ggtggagcgg ttgcagctaa tcaagtagag
     3301 ggagcatata atgaagatgg taagggctta tcagttcagg atgtgttacc caaaggtgga
     3361 ttaggagaag caacagaaaa tcctacagaa gataacttaa aattgatagg tattgatttt
     3421 tatcataaat ataaggaaga tatatccttg ttttctgaaa tgggctttaa tgtttttcgt
     3481 acttctattg catggagtag aatttttcca aaaggagatg aggaagaacc taacgaagct
     3541 ggtttgaaat attatgatga attatttgat gaactacatg ctcacgggat agaaccactt
     3601 gtaactcttt cacactatga gactccatta tatttagcaa gaaaatatca tggatggatt
     3661 gataggagaa tgattcattt ttatgaaaaa tttgctcgaa cagttttaga aaggtataaa
     3721 gataaagtta aatattggct tacatttaac gaagtaaact ctgttttgga attaccgttt
     3781 actagtggag gaatagatat acctaaggag aatctttcga aacaagaatt atatcaagct
     3841 atacatcatg aattagtcgc ctcgagtttg gttacaaaaa ttgctcgtga gattaattca
     3901 gagtttaagg tggggtgtat ggtattagct atgccagctt atccaatgac tccaaatcca
     3961 aaagatgtat gggcgactca tgagtatgag aatctaaatt atctattttc agatgtgcat
     4021 gttagaggtt attatccgaa ttatgcaaaa agatatttta aggaaaatga cattaacata
     4081 gagtttgcag ctgaagatgc agagttatta aaaaattata ctgtagattt tttatccttt
     4141 agctattaca tgagtgtgac tcaatctgct attccaacac agtataattc aggagaaggg
     4201 aatattattg gtggtttagt aaatccttat ttagagtctt cagagtgggg atggcaaatt
     4261 gatccaattg gactacgtat aattttaaat agatattatg accgttatca aatcccatta
     4321 tttatagtag aaaatggatt aggtgctaaa gatcaactaa taaaagatga acttaataac
     4381 ttaaccgtcc aagatgatta tagaattcag tatatgaaag aacatttatt gcaagttgct
     4441 gaagctctac aggatggtgt tgaaattatg ggctatacgt cttggggatg tattgactgt
     4501 gtttctatgt ccactgcaca actttctaaa aggtacggtc tcatttatgt tgatcgaaat
     4561 gatgatggaa atggcacatt caatcgatat aagaaaatgt cctttacttg gtataaagga
     4621 gtgattgaat caaatggaga atccttattc aaatagtttg tttattgatg attagatatt
     4681 atcacggtta aggcaacatc tcattaaata taaaataaag aggtttggaa gacatcaaat
     4741 tctaaacctc tttattttat agggggatta attaatttaa ttttgttaca gagagccgat
     4801 tataaatagt taacttagga tagattggtt atatatagta gactgaatct aaaatagtac
     4861 gaaacaattg ctaaaacatt tatagaaatt aattttactt tcccaatcga tttgttttca
     4921 tcttatttca atccgctata aagttagata agaataagct aacaagcaga agtaagatag
     4981 gtcttgcaag aatggtaaaa atctgataaa ctaagtagta attgaatagg aatctgaaag
     5041 actagtagcc caagggaagt atatcaggga ggagagccgt gactgcaagc tctctatatg
     5101 aaagctgggt gaattcactt gcgcatggat ttagaaatga aggtctgact tgtcagatga
     5161 aaacggatgg taccgcgtgt caacgctccg agtggagttt ttggcatgtg gttttctttt
     5221 tatctacgag agactgatgg aggaaatatg tcaactattg aagaacaatt aaaagcgctt
     5281 cgcgaagaaa cgctggctag cttgaagcag attactgctg gaaatgaaaa agagatgcaa
     5341 gatttgcgtg tctctgtcct tggtaaaaag ggttcgctca ctgaaatcct caaagggatg
     5401 aaagatgttt ctgctgagat gcgtccaatc atcgggaaac acgtcaatga agctcgtgat
     5461 gtcttgactg ctgcttttga agaaacagct aagctcttgg aagaaaagaa agtcgcggct
     5521 caactggcta gcgagagtat cgatgtgacg cttccaggtc gtccagttgc gactggtcac
     5581 cgtcacgttt tgacacaaac cagtgaagaa atcgaagata tcttcatcgg tatgggttat
     5641 caagtcgtgg atggttttga agtggagcaa gactactata actttgaacg tatgaacctt
     5701 ccaaaagacc acccagctcg tgatatgcag gatactttct atatcactga agaaatcttg
     5761 ctccgtaccc acacgtctcc agttcaggcg cgtgctatgg atgcccatga tttttctaaa
     5821 ggtcctttga agatgatctc gccagggcgt gtcttccgtc gcgatacgga cgatgcgacc
     5881 cacagtcacc aattccacca aatcgaaggc ttggtagttg ggaaaaatat ctctatggct
     5941 gatcttcaag gaacgcttca gttgattgtc caaaaaatgt ttggtgaaga gcgtcaaatt
     6001 cgtttgcgtc catcttactt cccattcaca gagccatctg ttgaggtgga tgtttcttgc
     6061 ttcaagtgtg gtggagaagg ctgtaatgta tgtaagaaaa caggttggat cgaaattatg
     6121 ggggccggta tggttcaccc acgtgtcctt gaaatgagtg gtatcgatgc gactgtatac
     6181 tctggctttg cctttggtct tggacaagag cgtgtagcta tgctccgtta tggaatcaac
     6241 gatatccgtg gattctacca aggagatgtc cgcttctcag aacagtttaa ataatgatta
     6301 gaaaagtaga aatggcagat gttgaggtgt tggctaaaat tgccaaacaa gcctttcgtg
     6361 aaacctttgc gtatgataat acggaagagc agttacagga atactttgaa gaggcttata
     6421 gtctgaaaac tttgtcaact gagttgggaa atcctgactc tgaaacctat ttcattatgc
     6481 atgaggagga gatagctggt tttctcaaag tcaactgggg aagtgctcaa actgagagag
     6541 aattagagga cgcttttgaa attcaacgcc tctatgtgct acaaaaattc caaggatttg
     6601 gactaggtaa gcaactgttt gaattcgcac ttgaacttgc tacaaaaaat agtttttctt
     6661 gggcttggct aggtgtttgg gagcataata caaaagctca agcgttttat aaccgatatg
     6721 gttttgaaaa atttagccaa catcatttta tggttggtca aaaagtagat acggattggt
     6781 tactgagaaa gaaattaagg taagaagaga attcttctat tgaaatgata ggaaaggaaa
     6841 agaaccagtg tggcaatggt cattctggag aactaaatta tgcttgtatc ttataaatgg
     6901 ttaaaagaat tggtgggcat tgatgtgcca tcacaggagt tggctgaaaa aatgtcaacc
     6961 acagggatcg aggtcgaagg tgtcgaatca ccagctgccg gtctttcaaa aattgtcgtc
     7021 ggtgagatct tgtcttgcga agatgtgcca gaaactcacc ttcatgtttg tcaggttaac
     7081 gttggcgaag aagaagagcg tcagatcgtt tgtggtgccc caaatgtgcg tgcaggcatc
     7141 aaggttatgg tggctcttcc gggagctcgt atcgctgaca attacaaaat caaaaaagga
     7201 aaaatccgtg gcttagagtc acttggaatg atctgttcac ttggtgaatt gggtatttct
     7261 gactcagttg tacctaagaa attcgcagat ggtattcaaa ttttgccaga aaatgccgtt
     7321 ccaggtgagg aagtcttttc atatctagac ttggatgatg aaatcatcga actttctatc
     7381 acaccaaacc gtgcagatgc cctttctatg cgtggagtgg ctcacgaagt ggcagccata
     7441 tatgacaagg cagtcaactt taaagaattt actttgacag aaacaaatga agctgcgaca
     7501 gatgcccttt ctgtgggcat tgagacagac aaggcgcctt actatgcagc tcgtatcttg
     7561 gacaatgtga ctatcgcacc aagtccacaa tggttgcaaa accttctcat gaacgaaggc
     7621 atccgtccca tcaataacgt tgtagacgtg acaaactaca tcctgctcta ctttggtcaa
     7681 cctatgcatg cttttgactt ggacacattt gaagggactg acatccgtgt gcgtgaagcg
     7741 cgtgctggtg aaaaattggt gaccttggac ggtgaagaac gtgacttgga cgtgaatgac
     7801 ctagtcatca ctgttgcaga caagccagta gcccttgcag gtgtcatggg tggtcaagca
     7861 acagaaatct ctgaaaaatc tagtcatgtt gtccttgaag ctgctgtttt caatggcaaa
     7921 tctatccgta agacaagtgg tcgcctgaac cttcgttctg agtcatcttc tcgctttgaa
     7981 aaaggaatta atgtggcaac agttaatgaa gcccttgatg cggcagctag cctgattgcg
     8041 gaacttgcag gtgcgacggt gcgtaagggt atcgtttcag cgggtgagct tgatacttca
     8101 gatgtagaag tttcttcaac tcttgctgat gttaaccgtg tcctcggaac tgagctgtct
     8161 tatgctgatg tcgaagacgt cttccgtcgt cttggctttg gtctttctgg aaatgcagac
     8221 agctttacag tcagcgtacc acgtcgtcgt tgggatatca caatcgaagc tgatctcttt
     8281 gaagaaatcg ctcgtatcta tggatatgac cgcttgccaa ccagccttcc aaaagacgat
     8341 ggtacagctg gtgaattgac tgtgacacaa aaactccgcc gtcaagttcg taccattgct
     8401 gaaggagcag gtttgacaga aatcatcacc tatgttctaa caactcctga aaaagcagtt
     8461 gagtttacgg ctcaaccaag taaccttacg gaactcatgt ggccaatgac tgtggatcgt
     8521 tcagtcctcc gtcaaaatat gatttcaggt atccttgata ccgttgccta caacgtggct
     8581 cgtaagaata aaaacttggc cctttacgag attggaaaag tctttgaaca aacaggtaat
     8641 ccaaaagaag aacttccaaa tgaaatcaac agttttgcct ttgccttgac aggcttggtt
     8701 gctgaaaaag atttccaaac agcagcagtt ccagttgatt tcttctatgc taaaggaatc
     8761 ctagaagcgc tctttactcg cttgggacta gaagtgacct atacagcaac agctgagatt
     8821 gccagccttc acccaggacg tacagcagtc atttcactcg gtgaccaagt tcttggtttt
     8881 cttggccaag tgcatccagt cactgctaag gcttacgata ttccagaaac gtatgtggct
     8941 gagctcaacc tttcagtcat cgaagctgcc cttcaacctg ctgctccatt tgtggaaatc
     9001 acgaaattcc cagcagtcag ccgtgacgtt gcccttctcc tcaaggcagc agtaactcac
     9061 caagaagtta tagatgctat ccaagctgcc ggcgtgaaac gtttgacaga tatcaaactc
     9121 tttgacgttt tctcaggtga gaaattggga cttggtatga agtcaatggc ttatagcttg
     9181 accttccaaa atccagaaga cagcttaacg gacgaagaag tcgcacgcta catggaaaaa
     9241 atccaagcat cgcttgaaaa aaaagtgaac gcagaagtgc gttaaacgat agtaggatac
     9301 aaattccccc tctagtttat gaacactaga ggggtgattt tatataatac tcaatgaaaa
     9361 tcaaaaagca aactaggaag ctagccgtaa gctgtacttg agtactgtaa ggcgaggctg
     9421 acgtggtttg aagagattgt cgaagagtat aaaataatta aaatgtgatt tctgtaaaaa
     9481 tacatctatg atcagagttt tgaaaactta caatgtctaa atctttaaca tagtagtggt
     9541 ttttaggcaa taaaatatga tctattgttg cattaaaaag ttttggactt tggctattcc
     9601 aagttcctct ttcaaaaggt ggtagtacat ttaatgcgtc cctatgagag cttatttttg
     9661 caagtgctcc atgacgcata gttgcattaa aatcatctgc aataatagcc tttggatatt
     9721 ttgaagccaa ttgattatga atgatgttta agtcttgctt ccagatttcc attaaacctg
     9781 gcagaggagg agcagtatgc aaggcaatga tatctggtat attttgtttt ctcgaatgta
     9841 atacaattgt cccgaaccgt gttgtatgaa aagttttagc ttctgtatag aaaccataac
     9901 ttttcttgac aatcacagtc acaggagcta ttccactatt ggtaggtgga gaagtgaaaa
     9961 tatcatagtt ggccatagaa agtccaactt gatgaaacaa tagtttgatt ctctggtttt
    10021 cttgctcacc tctgatattg gtagctagtt cagggaatat agccatatcg gcgtcaaaat
    10081 ggctaaaaat tcgctcaata tgttgtgctt ctatttgatt agcgacgttc caagttacta
    10141 attttaaggt tttagtctta tttgatgcag aagaaagggt tttatctgtt ccgaataata
    10201 gtaatatgag cgatagtaag agcaaaatgc cagagtaaaa ccgtatttgt ttatttttct
    10261 tgtaaaaaga tagggaaaaa aatacgaaac ttaaaatagc agccatagtt gcagtagcta
    10321 aggggaaggc ataaatctgt gccaagatag gtctggtaga tagccaaata ttaagattag
    10381 aagatggaaa aaaagaataa gttatgatag ggataacaaa gagaatgacc gaaagggcag
    10441 agagaaatgt tttaatcatt gtgtgagtac ctcaatttgc aatggttgct cggagctaat
    10501 gtgactttgt gactttactt gattgatatt ctttttcttg tcttcctcat agattaagta
    10561 caacccaagt aaaaaaagtc caatttaaga ttgaaatgat taaaaggcac agaaatgcaa
    10621 gacaattata ctacaaaagg caaacatttg acaatcgata gccgtcgctt aatcgaaaga
    10681 tggaaaaaag aagggaaatc aaatagagaa attgcctctc tgcttggaaa agttcctcaa
    10741 actatccaca ctgaaatcaa gcgtgggaca gtccgacaat gtcttggaaa agggcgcttc
    10801 aaagaggttt attctgccga ctatgctcaa cagtcttatg aaaacaatcg caagcgctcg
    10861 gtcaagaaat caagcttgac caaggaacta aaggaaaaga ttctccacta tcataaccaa
    10921 aaattttcgc ttgaaatgat ggtgatggct aaaggggtta acgtgggaat ttcaaccatt
    10981 tactattgga ttcatcgtgg aaaattgggg ttaagcaagc aggatctgct ttaccctaga
    11041 aaaggaaaag cgcttaagaa acaggctagc accaacttta aacctgctgg tcaatctatc
    11101 gaatcataat tcgctcattc ttttaaaaat acatagacgt aaaagaaaga gggttaagtg
    11161 atgaagaata gtgctattgg gagtaattgg aaggatgtcc atctgagctc tttagcaagg
    11221 aggaaatcct tgaaagtgat atgcgagtgg ctatcatgag cgagttgatt gaggctaggt
    11281 atgaacaagg aatcagtcag aaaaagctgg aagaagtcag tggagtgagt caacctgtca
    11341 tagctaggat ggaaacagga gagagcagtc ttcagttgga tacggtctta aaagttctaa
    11401 ccagtctagg aaagacacta gcagtcgttc cacttgaaca ggggaaaagt tgactagaat
    11461 cagttatagt cttttctaat aacaggtcat agtcacttat aagaattact aataacatgt
    11521 tttagtattc taattggaat atagctgtaa agtaagaatt acaaaggatt tgagacgttt
    11581 gcttcaagtc tttttctttt gtccgaaaca gatatatagt ttcaaactat atcaaaccct
    11641 aattttttac aattatacag acgctttctt ttctgttaag atagtttcaa caacaaattt
    11701 tggaggacac atcatgtcaa ctacaatcat cggtttccct cgtttgggcg aattccgtga
    11761 attaaaattt acaactgaaa aatactttag aaaagaaatc tcagaagaag aacttttagc
    11821 agcagcaaaa gacttgcgtg ctaaacactg gaacattgtc aaagaaaaag gcatcactga
    11881 aattccatca aatgactttt ctcactatga taacttccta gatgcggctt tccttttcaa
    11941 cgtggtgcct gcatccgttc aaaacttgga cttgtctgac cttgagcgct acttcgcttt
    12001 gggacgtggt taccagggag aaaaagggga cgttcgcgcc cttccaatga agaaatggtt
    12061 caacactaac taccactaca tcgttcctaa atttgaaaaa gacactcaag taaaattggc
    12121 tggtcacaag attttcgatg agttccaaga agccaaagaa cttggattga acactcgtcc
    12181 tgttcttgta ggtcccttca ctttccttca attgtcagac tttgaagaag gcgtgaaagc
    12241 agacgacttc gtagatagct tagtggctgc ttaccaagaa gtttttgcta aattggctga
    12301 acttggtgcg actcgcatcc aattggatga agcggctctt gtaaaagact tgacagctga
    12361 agaaaaagct ctcttcttga acctttacaa caaactcttg gctgacaaaa aaggtcttga
    12421 agtcttgctt caaacttatt tcggtgatgt tcgtgacgta tacgctgacc ttgtaaactt
    12481 accagtagat gctatcggtc ttgactttgt tgaaggtaag aaaactcttg aactcgttaa
    12541 aggtggcttc ccagctgaca agactctcta tgtaggtatt gtcaatggta aaaacatctg
    12601 gcgcaacaac tacgaaaaga gcttggctgt tcttgagcaa attccagctg aaaacatcgt
    12661 tttgacaagc tcttgctcac ttcttcatgt gccatttaca actgctaatg aagaatttga
    12721 accagcactc ttgaaccact ttgcctttgc agttgaaaaa ttggatgaaa tccgtgactt
    12781 ggatgctatc cgcaatggtc aaggttcaga agctcttgca gccaacaaag aactctttgc
    12841 gactgagcgt gttggtgaaa atgctgaact tcgtgcgcgt atcgctggct tgacagacgc
    12901 agactacact cgtttgccag cctttgcaga acgtgaagct atccaagaag aagctttcaa
    12961 acttccagct cttccaacaa caacgattgg ttcattccct caaacaaaag aagttcgtgc
    13021 caaacgtttg gcttaccgta aaggtgaatt gtctcaaaaa gagtacgatg ctttccttgc
    13081 tgaaacgatt gacgaatgga tcaagtggca agaagatatt gactttgatg tccttgttca
    13141 cggtgaattt gagcgtaatg acatggttga gtacttcggt caaaacttgt caggatacct
    13201 cttctctaaa aatggatggg tacaatcata cggtatgcgt ggggtaaaac caccaatcat
    13261 ctggggtgat gtcactcgtc ttaaccctat cactgttaaa tggtctagct atgcacaaag
    13321 tcgtacaaac aaacctgtta aaggtatgtt gactggacct gttaccatcc ttaactggtc
    13381 attcccacgt gaagacatct ctatcaagga ttctactctt caaatcgccc ttgctatcaa
    13441 ggatgaagtg cttgaccttg aagctgctgg tgtgaaaatc atccaaattg atgaggctgc
    13501 tcttcgtgaa aaattgccac tccgtcgtag tgactggtac gaagattacc ttgactgggc
    13561 aattcctgcc ttccgcttgg tacactcaac agtagcgtca gacacacaaa tccacactca
    13621 catgtgttac tcagaattta cagatatcat cccagctatc gataacatgg atgcagacgt
    13681 tatttccttt gaagccagcc gttcaaacct tgaaatcttg gacgaactca aagcgaaaaa
    13741 cttccaaaca gaagtgggac ctggggttta cgatatccac tcacctcgtg taccaaatga
    13801 aggcgaaatc gacaacacaa tcgaagccat ccttgctaaa gtgccaagca agaaagtttg
    13861 gatcaaccct gactgtggtt tgaaaacacg tggtatccca gaaacaaaag aaagcttgat
    13921 ccgccttgtt gaagcagcta aagctgcgcg tgagaaattg taagattgga tttctctcca
    13981 tacagtggtt gttcaaaaag aaatcaacta gaaaaggtta ttacatatgt cacgccaaac
    14041 accgtcactc tcatttgaag tgttccctcc aaacccagcc gtgggtaatg gtaacattat
    14101 ttcagccttg caggatatgc aggagttggc tccccatttt atcagtgtaa ctgccagcaa
    14161 taataaattt aatatcaagg aaacgacggt tcgtttggct gactttatcc aaaatgactt
    14221 ggcgattccg accattgccc acttgccagc tatttatcta actaaggaca aggttgctga
    14281 aactattgct gacttggaca aagttggggt tcagaaaatc ttggctcttc gtggggatat
    14341 tattccagac gtagaaccac aaaaggattt ccgctatgca accgacttga ttgagtttat
    14401 caaggaacaa gcccctcact ttgatattat tggagcttgc tatccagaag ggcatccaga
    14461 ttcgccaaat cagatttcag atattcaaaa tcttaagaag aaagtggatg caggctgttc
    14521 gagcctcgta actcagctct tctttgacaa tgagcgcttc tatgattttc aggacaagtg
    14581 tatcttggct gggattgatg ttcctattca tgcaggaatt atgccaattc tgaatcgaaa
    14641 tcaggctctc cgactcttga agacttgtga gaatatccat cttccacgca aatttaaagc
    14701 catcttagac aagtatgagc atgaccctga gtcgctcaga gcagcaggac ttgcctatgc
    14761 agtggaccaa atcgtggact tggtaactca ggatgttgcc ggtgtgcatc tctatacgat
    14821 gaataatgct gatacagcaa aatacatcca tcaagcaacc catgccttgt ttaatcacca
    14881 gtctctagga taataaaagc aaaccattct tctcaggtga ggggaatggt tcctttttaa
    14941 tggtaaagac ctcacttttt aagaaaaata tgataaaata gattctgtac gtacttgata
    15001 caaagatgaa ggtattaaat aatacaatgc atttaaactg taagatttaa cgacacgagt
    15061 gagtcaaatc gatgttattt gacgaaagag ttagtaaagc atttagctaa tcgcccgata
    15121 gcgattagcg tgaaaggttt agatacttta atattaaacc tttctaatga tgtatcttga
    15181 aaactgaaca cgcctacaac tctgtggaaa aagataaatc tgcctaggag cagtcgctcc
    15241 gtcgttcgat ttcctatctt cctttgagtt gcttgacggc ttggtatctt gatgacttga
    15301 attttggtct catttcttag gaaaaaagat aagcttccta gcactcgtcg agtgcgacgt
    15361 caccttccta tttttctaca gaaatgttcg gcaagccgaa ccgtccaaaa tatcttgtgt
    15421 aattgaacac ggccgaaaag ctgtgtaaaa aagataaact gtcttgtctt catcgaagac
    15481 ttcgtcagtt tcctattttt actttgcttt tgacgtcctt ggtatcttga tctttgtagg
    15541 caaggcgtat aatttcatca atccaaaggg gattaaaatg gcaaaacaag tgtttcaaac
    15601 gacttttgcg ggtcgtgagt taattgtaga gactggtcag gttgctaagc aagcaaatgg
    15661 ctctgttgtc gtacgttacg gtgagtcaac tgtcttgact gctgccgtta tgtctaagaa
    15721 aatggcaact ggggattttt tcccactcca agtcaactac gaagaaaaaa tgtatgcggc
    15781 tgggaagttt cctggtggct ttatgaaacg tgaaggacgt ccttcaacag atgcgacctt
    15841 gacagcgcgt ttgattgacc gtccgattcg tcctatgttt gcggaaggtt tccgtaatga
    15901 agtccaagtc atcaatacag tgctttctta tgatgaaaat gcatctgcac caatggctgc
    15961 tatgtttggt tcatctttgg cactgtctat ttcagatatt ccatttgacg gaccaattgc
    16021 tggggtacaa gtgggatatg tagatgacca aatcatcatc aacccaagtc aagaacaagc
    16081 agagcaatct cttcttgaat tgacagtagc tggaactaag cacgctatca acatggtaga
    16141 gtctggtgcc aaagaattgt cagaagaaat catgttggaa gcgcttctta aagggcacga
    16201 agctgtcaaa gaattgattg ccttccaaga agaaatcgtt gctgctgtcg gtaaagaaaa
    16261 agcagaagtg gaattgcttc acgtggatgc tgaattgcaa gctgaaatca ttgcagccta
    16321 caacagtgac ctccaaaagg cagttcaagt agaagagaaa ttggcccgtg aagctgcaac
    16381 tcaagcagtg aaagaccaag tgactgccgt ttacgaagaa aaatatgcgg accacgaaga
    16441 atttgaccgt attatgcgtg atgtggctga aatcttggaa caaatggaac acgcagaagt
    16501 gcgacgttta attacagaag acaaggtgcg tcctgatggt cgtaaggtcg atgaaatccg
    16561 tcctttggat gcggttgttg acttccttcc tcgtgtacat ggttcaggtc tctttactcg
    16621 tgggcaaact caagctcttt cagtcttgac cttggctccg atgggagaaa ctcaaatcat
    16681 tgatggtttg gatccagagt acaagaaacg ctttatgcac cactataact tccctcaata
    16741 ttctgtaggg gaaacaggtc gttacggtgc gccaggtcgt cgtgaaatcg gtcacggtgc
    16801 ccttggtgag cgtgctcttg ctcaagtctt gccaagcttg gaagaattcc catacgctat
    16861 ccgtctagta gcagaagttt tggaatcaaa cggttcttca tctcaagctt ctatctgtgc
    16921 gggaactctt gcccttatgg ctggtggtgt gccaatcaag gcgccagtag ctggtattgc
    16981 tatgggactt atctcagatg gaaataacta cacagtattg acagatatcc aaggtttgga
    17041 agatcacttt ggagatatgg acttcaaggt tgcaggtact cgtgatggga ttacagccct
    17101 tcaaatggat atcaagattc aagggattac tgcagaaatc ttgacggagg ctcttgctca
    17161 agccaagaaa gcgcgttttg aaatccttga tgtcattgaa gcaaccattc cagaagttcg
    17221 tctagaattg gctccaactg ctccgaaaat tgatacgatc aagattgatg tggacaagat
    17281 taagattgtc atcggtaagg gtggagaaac catcgacaag attatcgctg aaacaggtgt
    17341 taagattgat atagacgaag aaggaaatgt gtctatctac tctagtgacc aagatgctat
    17401 taaccgtgcc aaagaaatta ttgctggttt ggttcgtgaa gccaaagtgg atgaagttta
    17461 ccgtgctaaa gtcgttcgta tcgagaaatt tggtgccttt gttaacctct ttgataagac
    17521 agatgccctt gttcatatct ctgagatggc ttggactcgt accaatcgtg tagaggattt
    17581 ggtagaaatc ggggatgaag ttgatgttaa ggttatcaag attgatgaaa aaggccgtat
    17641 cgatgcctct atgaaggctc ttctacctcg tccgccaaaa cctgagcatg atgaaaaagg
    17701 tgaaaagtct gagcgtcctc accgcccacg tcatcacaag gatcacaaac ctaagaaaga
    17761 atttacagaa acaccaaaag attcagaata agaaaaggag aaatgtatgg ggtggtggcg
    17821 cgaaaccatt gatatcgtaa aagaaaatga tccagcggcc cgcaccactt tggaggtttt
    17881 gctgacttat ccaggtgtca aggccttggc ggcccaccgt ctctcgcatt ttatctggaa
    17941 gcacggcttc aaactcttag ctcgtatgca cagtcagttt tggcgctttt ggactcagat
    18001 tgagattcat ccaggagccc agattgattc aggtgtcttt attgaccatg gttctggtct
    18061 ggtgattgga gagacagcga ttgttgaaaa aggcgttctt ctctatcacg gagtgactct
    18121 tgggggaaca gggaaagact gtggcaaacg ccatccgact gtacgaaagg gagccctcat
    18181 atcagcccat gcccaagtta tcggacctgt ggaaattggt gaaaatgcca aggtcggtgc
    18241 tgcagcagtt gtcgtagcag atgtacctag tgatgtgacg gttgtcggta ttccggccaa
    18301 gattgtccgt cttcatggta agaaagatga gcctgtcatt cacgaagtcg aagaaaaacg
    18361 agagtattat gtcaataaac tcgagcaggc taaagatgcc agtcacagat cgtctggttt
    18421 gtagaggata cctatatgat tcaagtaaga aacaagttaa gccaagagga gctatctgag
    18481 gcgaaaaaag taattaactg ttgccaaaac tatgacggta cctatcgcga tccctatctc
    18541 tctaacatgc ttaattttga cccaaacatg cccgcctttt tcctttatta tgaaaaaggc
    18601 gaacttgttg gtttattaac tgtctatgca gatgaccaag atgtagaagt gacgatactg
    18661 gttcatccag gtcatcgccg tcaggggatt gcgcgtgcat tgtttactag ttttgagaga
    18721 gaaacagctt ctttccccat tcgatcagtc acttttcaga cagaacgtat ttttttagag
    18781 aatcatcctg actttgccag taactgggga ctaatcgagg atgaagagac agaaacttgg
    18841 ttaggtaagg atagaagacc ttatccgtta gcaaatgttt cccatattga agttttgtta
    18901 gcagatagtt cgtatcagga tcaaattagt caattaaaat ttcaggcatt ttcagaggaa
    18961 catgaatcga gagaagttgt ggatagatat gtcgctgaag ctctgaagga tccagaaagc
    19021 cgactatata ttttgttaaa agacggtcag gttattggga cttgcacggt agatttatcg
    19081 actaatacga attacttcta cggtttagca atatcggaac ctgaacgtgg gaaaggctat
    19141 ggaagctact tagcaaaatc cctcgtcaac caactaattg agcaaaatga caaggaattt
    19201 cagattgcag tggaagatag caatgtaggt gccaaacgtt tgtatgaaaa aattggcttt
    19261 gtcaaacaga ctcaggtggt ttatctgaat gagaaaggag caagggattc cgaagtgtag
    19321 agatattcgg actgaaattt acttgaactt ttagtgatga aactaattgt tcttggattt
    19381 cagctttctt gattatgatt tatgattaaa atctatgaca ccatgtctcg tgatttgcga
    19441 gaatttgtcc cgattgagga cggcaagatc aagatgtatg tttgtgggcc aacggtgtac
    19501 aactatattc atgtagggaa tgctcgttca acggtagctt ttgataccat tcgtcgctat
    19561 tttgagtatc gtgggtacga ggttgcctat atttccaatt ttacggatgt ggatgataag
    19621 attatcaacc gtgccaggga agaaggcatc acgcctcagg aggttgcgga taagtacatc
    19681 gctgcctttc gtgaggatgt gacggccttg ggcgtgaaac ctgcgactcg ccatccgcgt
    19741 gtagtggagt ttatggcaga catcatccgt tttgtggaag gcttgatcga gaaaggcttt
    19801 gcctatgaga gtcaagggga tgtctatttc cgtgtagaaa aatcccacaa ctatgctaaa
    19861 ttggctaata aaaccttgga agatttggag ctaggtgctt caggtcgtac cgatgaagaa
    19921 acggctcgta aggaaaatcc tgtagacttt gctctatgga aatcttccaa accaggtgag
    19981 atttcttggg atagtccttg gggacctgga cgtccgggtt ggcatattga gtgttcagtc
    20041 atgtcgacag agattttagg tgataccatt gatattcacg gtggtggagc tgacctagag
    20101 tttccacacc acaccaatga aattgcccaa tctgaagcta aaacaggcaa ggcttttgct
    20161 aactactgga tgcacaatgg ctttgtcaat atcgacaatg tcaaaatgtc taagtccttg
    20221 ggtaacttca ttacggtaca cgatgccctt aaaactcttg atgggcaagt acttcgtttc
    20281 ttctttgcga cccagcacta ccgtaagcct atcaacttca cggaaaaggc agttcgcgat
    20341 gccgagacca atctcaagta tctgaagaat acttacgaac aaccatttac aggaaacgtg
    20401 gatgcccaag agttacaaaa ctttaaagat aagtttgtag cagctatgga tgaagatttt
    20461 aatgctgcca acggtatcac agttgtcttt gaaatggcca aatggatcaa ctcagggaac
    20521 tatgatgcaa gtgtcaagca agctcttgca gatatgttag aaatttttgg aattgtcttt
    20581 gttgaggaag ttttggatgc agagattgaa gacttgattc aaaaacgcca agaggcgcgt
    20641 gccaatcgtg actttgcgac agcagaccaa atccgtgacc aattggttac tcaaggaatt
    20701 aagctccttg ataccaagga tggagtgagg tggacacgtg attgatgtca atctcattaa
    20761 cgggattgcg ctagcctttg agggagatgc ggtgtattct atgtatattc gccgccacct
    20821 catcctcaaa ggtatgacca agcccaataa actccaccaa gaggcgacca agtacgtgtc
    20881 agccaaggct caagctcgcc tgatttctct catgttggag gagcagatcc taacggaaaa
    20941 agaagaagaa atctacaaac gtggccgcaa taccaatagt cacacaaagg ctaaaaatgc
    21001 agatgtcgtg acttatcgta tgtccacggg atttgaagca gttatgggct atctccatat
    21061 gactgagaat ctggaacgtc ttgagagttt ggtttcatgg tgcatccaaa aagtggaggg
    21121 ctagaacatg agggcaaaag aactacaaga ctggtttcct gaggctcgga tttcagacca
    21181 accagtagag aaagagggct atctcacgct tcctttagct tctcagcagt ggattttgct
    21241 ggaggaagct gggctcagcg agcgtgaaaa gcagttggtt gcccttttga cccagcagga
    21301 gcaggctcgt tcgctaaacc cttggtattc ctatctggtt gaaggcaagg gacaggcacc
    21361 gcaagttttt aaaaagattc agttggttta ttgccatctt tcttattttc agcaggaaaa
    21421 tctggcttct tggctagata tgatgcggac tctttttccg aattgtcaga cagtgttaca
    21481 ggtcggagct caggattatg ttttcgtgct tcaacaagac aaatacactt ctgtaagaga
    21541 tattttaagt gatatgattg aagcagttga gtatgacttt ggacttcgtc tttctatcat
    21601 gttgggtcag gtttggtctc agacaggaca tcaagcccta tcagacttaa tcaaagctga
    21661 gcgggatttg ttcaagacat ggtggcgtca gggtcaccaa ggtgttcata ctttttctca
    21721 gctctatctt tggagtatgg gagaaagact cgtggacttg aagccaatta aagaatgtct
    21781 acaccagatg attttggatc aagatcagat tcaggaaatc attctctctc tttgggaaaa
    21841 tagtgctgtt ctcactaaaa cagcccagca actctatctg caccgcaatt ctctccaata
    21901 caagattgat aaatgggaag agttgacagg gcttcagttg aaagagttga ccgacctgac
    21961 cttgtgttat caattgattt taggttcttt gtcaactata gttggtttgt aaagaag
//
LOCUS       DAVBIC010000039        21576 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.039, whole genome shotgun sequence.
ACCESSION   DAVBIC010000039 DAVBIC010000000
VERSION     DAVBIC010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21576)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21576)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21576
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.039"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            complement(72..1091)
                     /locus_tag="VQ664_001466"
     CDS             complement(72..1091)
                     /locus_tag="VQ664_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HET2789615.1"
                     /translation="MLYVGIDIAKNKHDVTALNVPGKTVLKPLTFSNNKAGFELLDLS
                     LRQLNQDCLIALENTGHYAFNLLNFLHEQGYKVYTYTPLLIKEFAKSLSLRKTKTNKK
                     DAHGIALKLLSDPNREQFQHDNRQVELKILARHIHRLKKKQSDWKVQYTRCLDIIFPE
                     LDKIVEKHSEYTYQLLTCYPNPQKRLEAGFDKLIEIKRLTASKIQDILSVAPRSIGTT
                     SPAREFEIIKHYKRLIDKAETCVNDLMAEFNSVITTVTGIGNRLEAVILAEIRNIHAF
                     DNPAQLQAFAGLDSSIYQSGQIDLAGRMIKRGSPHLRWALIQAAKACPRFSPAFKAYL
                     KTKLE"
     gene            1346..2191
                     /locus_tag="VQ664_001467"
     CDS             1346..2191
                     /locus_tag="VQ664_001467"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HET2789616.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
     gene            complement(2338..3399)
                     /gene="dinB"
                     /locus_tag="VQ664_001468"
     CDS             complement(2338..3399)
                     /gene="dinB"
                     /locus_tag="VQ664_001468"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HET2789617.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIRDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKSVGLQIRAI
                     FKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGVSYNKF
                     LAKMASDYQKPHGLTVILPEQAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILLAEEDIKKEL
                     TLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSLAQKTQDASQISQIALQLYE
                     ELSKKERGVRLLGITMTGF"
     gene            3747..6071
                     /gene="pflB"
                     /locus_tag="VQ664_001469"
     CDS             3747..6071
                     /gene="pflB"
                     /locus_tag="VQ664_001469"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HET2789618.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIEPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDRYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
     gene            complement(6438..6656)
                     /locus_tag="VQ664_001470"
     CDS             complement(6438..6656)
                     /locus_tag="VQ664_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789619.1"
                     /translation="MMSIREQDLQDIGAIIKYKNFHSPFDTFKYLKDMGFDTIDLSVL
                     LEGFSYAYGMDWLEKFFKENQDKLREFY"
     gene            complement(6752..6990)
                     /locus_tag="VQ664_001471"
                     /pseudo
     CDS             complement(6752..6990)
                     /locus_tag="VQ664_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397100.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(6983..7267)
                     /locus_tag="VQ664_001472"
     CDS             complement(6983..7267)
                     /locus_tag="VQ664_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789620.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVEKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            complement(7879..8049)
                     /locus_tag="VQ664_001473"
     CDS             complement(7879..8049)
                     /locus_tag="VQ664_001473"
                     /inference="COORDINATES: protein motif:HMM:NF024172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2789621.1"
                     /translation="MTKQVPKFTKDTAQLYTCKWLLYNKVTKMYDHTVVNHSVREYIT
                     DSISTNTIEETG"
     gene            complement(8699..9922)
                     /locus_tag="VQ664_001474"
     CDS             complement(8699..9922)
                     /locus_tag="VQ664_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HET2789622.1"
                     /translation="MITKQSAFLQNRATILEFLYRNPATSRTDIVNETGLTPATTTNI
                     IKELSEQSLIYETGDEFSEFSGSGRRRKTISITDNIPYVVGGIEINVLGIFLSLCDLQ
                     GKTLFETEILNEDYPISEINSTITNMIKTAIEYVPLETKLLGFGLSIPGHYNKDSGSI
                     ITNNPIWESFNLLNVIKRFNFPFIVKNNIDCMAIGQYLFNPHNTPDNFIFLHAGLGIY
                     TSFFTKEKIGASKNPYIGEIGHTIVELNGQYCECGKKGCLQTYISDAWLIKHAQLLFK
                     NSQLTVLKSLVKTEKDIHLDTLLTAYNLGDSALRQQIDKGVNLLATSIANLLLINPAD
                     KIYINSQLLNYQPFTHEVRDKIQDQLHFVPFTRNIEIEILPYNKHRGSIGACALAIVA
                     FFIEHSNVLQDIISP"
     gene            10090..11412
                     /locus_tag="VQ664_001475"
     CDS             10090..11412
                     /locus_tag="VQ664_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET2789623.1"
                     /translation="MNNILAFLETKVAPFGEKVGNQRHLKAIREGFMMAMPLILVGSL
                     FLILISWPQEDFTNWLNSVGLLSILTTMNQSTVAIISLVACFGIAYRLSEGYGTDGPS
                     AGIIALSSFVLMAPRFSSMVYDKNGEQVKQLFGGAIPFSSLNASSLFMAITIGLVTAE
                     IYRMFIQRGITIKMPSGVPDVVSKSFSALLPGFTTFVLWALVLKGLEAAGVAGGLNGL
                     LGAIVGTPLKLIAGTLPGMILCVIVNSFFWFCGVNGGQVLNAFVDPVWLQFTTENQEA
                     VAAGQTLQHIITLPFKDLFVFIGGGGATIGLAICLFLFSKSRANKTLGKLAIIPSIFN
                     INTAILFTFPTVLNPIMLIPFIATPTINALITYVSMAVGLVPYTTGVILPWTMPPIIG
                     GFLATGASWRGALLQVVLILVSVAIYYPFFKIADKRNLEKEKATVGGK"
     gene            11414..13300
                     /locus_tag="VQ664_001476"
     CDS             11414..13300
                     /locus_tag="VQ664_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000236922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4838 domain-containing protein"
                     /protein_id="HET2789624.1"
                     /translation="MVIRVFDQQKNTYSSFALEELSYYINRVFKTDIELVEEKEADIF
                     VGLVNKEDRKDHVLISLDKGKGRIESNTIVGLLIGIYRMFHEFGVVYTRPGRGHDFVP
                     ELRFEDFLDKELSIDETASYYHRGVCIEGADSFENILDFIDWLPKIGMNSFFIQFENP
                     YSFLKRWYEHEFNPYLNKEKFSNELVQELSDRLDKELQKRGLIHHRVGHGWTGEVLGY
                     SSKFGWESGLSISEEKKPYVAEINGKRELFNTAPILTSLDFSNPDVADKMVEIIKDYA
                     KKRPDVNYLHVWLSDARNNICECENCRQELVSDQYIRILNQLDRALTSEGLDTKICFL
                     LYHELLWAPQKEKLDNPERFTMMFAPITRTFEMSYADVDFDNSIPTPKPYLRNKIILP
                     NSLEENLSYLFEWQKTFKGDSFVYDYPLGRAHYGDLGYMKISQTIYRDVSYLSNLHLN
                     GYISCQELRAGFPHNFPNYVMGEMLWKKTRSYEELIEEYFSALYGSNWQSVVEYLEKL
                     SSYSSCDYFNAIGSRQNDVLANHYYIAYNLADNFLPIIEENISKLLNSQKDEWKQLSY
                     HREYVVKMAKALYLQATGKTRQAQDEWRNVLNYIRGHELLFQSNLDVYRVIEVAKNYA
                     GFHL"
     gene            13468..13812
                     /locus_tag="VQ664_001477"
     CDS             13468..13812
                     /locus_tag="VQ664_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000836781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET2789625.1"
                     /translation="MKSKEEINMLGFTIVAYAGDARSDLMDALAFARDGYFEQARELV
                     ESANDSIVSAHREQTNLLAEEASGDNFEVSFIMIHGQDTLMTTMLLYDQVKFFIDEYE
                     RIRKIEEHIGLQ"
     gene            13822..15234
                     /gene="lacG"
                     /locus_tag="VQ664_001478"
     CDS             13822..15234
                     /gene="lacG"
                     /locus_tag="VQ664_001478"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HET2789626.1"
                     /translation="MENLQVKALPKEFLLGAATAAYQVEGATRVDGKGTNMWDVYLQE
                     NSPFLPDPASDFYYRYEEDITLAAEHGLQALRLSISWVRIFPDIDGEPNILAVRYYHR
                     VFQSCLKHNVIPFVSLHHFDSPQKMLETGDWLNRENIDRFIRYARFCFQEFTEVKHWF
                     TINELMSLAAGQYIGGQFPPNHHFQLSEAIQANHNMLLAHALAVLEFHQLGIEGEIGC
                     IHALKPGYPIDGQKENILAAKRYDVYNNKFLLDGTFLGYYSEDTLFHLNQILEANNSS
                     FIIEDGDLEIMKRAAALNTMFGMNYYRSEFIREYKGENRQEFNSTGIKGQSSFKLNAL
                     GEFVKKPGIPTTDWDWNIYPQGLFDMLLRIKEEYPQHPVIYLTENGTALKEVKPEGEN
                     DIIDDSKRIRYIEQHLHKVLEARDRGVNIQGYFIWSLQDQFSWANGYNKRYGLFFVDY
                     ETQKRYIKKSALWVKGLKRN"
     gene            15304..16983
                     /locus_tag="VQ664_001479"
     CDS             15304..16983
                     /locus_tag="VQ664_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HET2789627.1"
                     /translation="MDKLVAAIEKQQGKFEKISTNNYMIAIKDGFIATMPLIMFSSFL
                     MIIIMIPKNFGVELPSPAIAWMRKVYMLTMGVLGIIVSGTVAKSLAGNVNRKMPPGKV
                     INDTSAMLAAICGYLVLTVTLVVDEKTGSTSLSTNYLGSQGLITSFVSAFITVNVYRF
                     CIKRDITIHLPKEVPGAISQAFRDIFPFSFVLLISGLLDIVSRFSLDVPFAQVFQQLL
                     TPIFKGAESYPAMMLIWFMCALLWFVGIHGPSIVLPAVTALQLSNMEENAQLLANGQF
                     PYHSLTPNFGNYIAAIGGTGATFVVPFILIFFMRSKQLKSVGKATITPVLFAVNEPLL
                     FGMPVILNPYLFVPFLMTPPVNVFLGKVFIDFFGMNGFYIQLPWAFPGPLGLLIGTNF
                     QLISFVFLSLMLVVDILIYLPFCRAYDRQLLVKEDIASSNDIILEEDTSEIMPGEIDV
                     IKSKELKVLVLCAGSGTSAQLANAINEGAQLAEVRVIANSGAYGAHYDIMGVYDLIIL
                     APQVRSYYREMKVDAERLDIQIVATRGMEYIHLTKSPSKALQFVLEHYQAV"
     gene            complement(17109..18548)
                     /locus_tag="VQ664_001480"
     CDS             complement(17109..18548)
                     /locus_tag="VQ664_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HET2789628.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSLIDAF
                     FEISSGFTTTGASILNDVSVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYLALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRIKAFFGDEELRAYL
                     VIVLVSTGLISLNTLYLYPGFSKSFEMTFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMAIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNKTVIDKDTQHK
                     ILKYFVIYAMILLALIFIVSLDSNDFLVVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(18552..19901)
                     /gene="trkA"
                     /locus_tag="VQ664_001481"
     CDS             complement(18552..19901)
                     /gene="trkA"
                     /locus_tag="VQ664_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HET2789629.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            20089..20937
                     /locus_tag="VQ664_001482"
     CDS             20089..20937
                     /locus_tag="VQ664_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HET2789630.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            20952..21500
                     /locus_tag="VQ664_001483"
     CDS             20952..21500
                     /locus_tag="VQ664_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HET2789631.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLVGYGLWWTWIIASGLFGLVVGLFRKYVRVING
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
BASE COUNT         6518 a         3674 c         4437 g         6947 t
ORIGIN      
        1 tttaggatat aaaacagggt tcggataagt ttttttgcaa ggtggatgat ggctacattg
       61 taatgttttc cttattctaa cttagtctta agataggcct taaaagcagg tgaaaagcga
      121 gggcatgctt tggcagcttg tatgagtgcc caccgcagat gaggggaacc ccgtttgatc
      181 attcttccag ctaaatcaat ctgacctgac tgataaatag aagaatccag tccagcgaaa
      241 gcttgtaatt gagcaggatt atcaaaggca tgaatatttc gaatctcggc taaaatgacc
      301 gcctctaaac gattcccaat cccagtgacc gtcgtgatga ccgagttgaa ctcagccatc
      361 aagtcattga cacatgtttc cgccttgtca atgagcctct tgtaatgttt gatgatttcg
      421 aattcacgag caggagatgt tgttccgata gaacgaggtg caactgagag gatatcctga
      481 attttagaag cggtcaatcg cttaatttct atcagcttat caaatcctgc ctcaagcctt
      541 ttctgaggat tagggtagca tgtcaagagt tggtaggtat attctgaatg cttttcaacg
      601 attttatcca actcaggaaa gatgatatca agacaacgag tgtattgtac tttccaatca
      661 gactgttttt tcttgagacg atgaatatgt ctagccagta tttttagttc tacttgccga
      721 ttatcgtgtt gaaattgttc acgattgggg tcagaaagaa gtttaagagc gatgccatga
      781 gcgtctttct tattcgtttt agtcttgcga agtgataatg atttggcaaa ttccttgatg
      841 agcaaaggag tgtaggtgta aactttatat ccttgttcat gcaggaagtt cagtagatta
      901 aaggcataat gtccggtatt ttcaagagcg atgagacagt cttggttgag ctgtcgaaga
      961 gacagatcta agagttcaaa accagcttta ttatttgaaa aagtgagtgg tttaagaaca
     1021 gtttttcctg gaacattcaa ggctgtaaca tcgtgtttat ttttagcgat atcaatgccc
     1081 acataaagca tgggagtacc tccagatata gtatttcaag tctacttggt tatccacgaa
     1141 ttttttgcct tgttacctta gacgagatca aacgtctatg cgttatcaaa ctcattacca
     1201 attgaaacaa aagctgtggt tagagccttt cggaaatcgt caagcgattg gaggaaatga
     1261 actaatccac agtggcttat tccaagtata ccacttgggc tttggcagta gctaactgcg
     1321 ctaattataa tatagggagt aatctatgta tcttattgaa attttaaaat ctatcttctt
     1381 cgggattgtt gaaggaatta cggaatggtt gccgatttcc agtacaggtc acttgatttt
     1441 agcagaggaa ttcatccaat accaaaatca aaatgaagcc tttatgtcca tgtttaatgt
     1501 cgtgattcag cttggtgcta ttttagcagt tatggtgatt tattttaaca agctcaatcc
     1561 ttttaaaccg actaaggaca aacaggaagt tcgtaagact tggagactat ggttgaaggt
     1621 cttgattgct actttacctt tacttggtgt ctttaaattt gatgattggt ttgataccca
     1681 cttccataac atggtttcag ttgctctcat gttgattatc tacggggttg ccttcatcta
     1741 tttggaaaag cgcaataaag cgcgtgctat cgagccaagt gtaacagagt tggacaagct
     1801 tccttatacg accgctttct atatcggact cttccaagtt cttgctcttt taccagggac
     1861 tagccgttca ggtgcaacga ttgtcggtgg tttgttaaat ggaaccagtc gttcagttgt
     1921 gacagaattt accttctatc ttgggattcc tgttatgttt ggagctagtg ccttaaagat
     1981 tttcaaattt gtgaaagccg gagaactctt gagctttggg caattgtttt tgctcttggt
     2041 cgcgatggga gtagcttttg cggtcagcat ggtggctatt cgcttcttga ccagctatgt
     2101 gaaaaaacac gacttcaccc tttttggtaa ataccgtatc gtgcttggta gtgttttgct
     2161 actttacagt tttgtccgtt tatttgtata agaaaaacct tgaaggggca actcttcaag
     2221 gttttatact cttcgaaaat ctcttcaaac cgcgtcagct ttatctgcaa cctcaaaaca
     2281 gtgttttgag cagcctgcgg ctagcctcct agtttgctct ttgattttca ttgagcttta
     2341 aaatccagtc atggtaatcc ccaataggcg gacacctctt tctttcttgc ttaattcttc
     2401 atagagttgc agggctattt ggcttatctg actagcatct tgtgtttttt gagcaagact
     2461 ttttcgtttg gtaagagttg aaaagtcctc gtagcggatt ttcaaaatga caatttttcc
     2521 agctttttct tgttgatgta gattgagagc gactttttct gatagaagag tcagctcttt
     2581 tttgatatct tcctcagcaa ggagaatctt cccgtaggtt ttctccttgc cgattgattt
     2641 acggatgcga ttggatttga ctggagagtt gtgaatgcca cgagcctttc gatacagatc
     2701 atagcctagt ctaccaaaac ggtctattag ggttacctca ggaacttcaa gtaaatcagc
     2761 accagtaaaa acgcccattt gatgaagacg ttctactgtc ttttttccta ctccatgaaa
     2821 tttggaaata tccatttgtt tgagaaaatc ctcagcctgt tcaggtagaa tcactgtcaa
     2881 accatgtggt ttttgataat cactcgccat tttagctaag aatttgttgt aagaaacgcc
     2941 tgcggaagca gttagatgga gttcttgcca gatatctttt tgaatgaggc gagcaatttt
     3001 gaccgctgac ttgataccga gtttattttc tgtcacatcc aaataggctt cgtcaatgct
     3061 catgggttca atcaaatctg tatagcgctt aaaaatagct cgaatctgga gtcccacaga
     3121 cttgtatttc tcataattcc ctgagataaa gacagcctgg ggacaacgtt cataagcttc
     3181 cttggaactc atggcagaat ggacaccaaa agctcttgcc tcataactac aggtagaaac
     3241 gactccccgt ccacctgttt gccgagggtc gcttccaata atgacaggtt ttcctctgag
     3301 tttaggatta tccctgattt ccactgcagc aaaaaaggca tccatgtcaa tatggatgat
     3361 ttttcttgac aaatcattta acaaaggaaa aatcaacatg cctagcacct ttttatactc
     3421 ttcgaaaatc tcttcaaacc acgtcagctc tatctgcaac ctcaaaacag tgttttgagc
     3481 aatctgcggc tagcttccta gtttgctttt cgatttccat tgagtgttac tgcttatttt
     3541 cttttattat accctttttt ctgaaaaaaa gaaaaaagga ctttattttt tcaaaaatat
     3601 aatacagttt gaaataaaat atagactgtt ttagaaaaga aagtgtaaaa atagggaatt
     3661 ttcacttgtt gaaatcggtt actatatggt atacttgtct tatgaatgta acagatgact
     3721 gttactagaa aaaagaggac attaatatgg ttgttaagac agttgttgaa gcacaagata
     3781 tttttgacaa agcttgggaa ggcttcaaag gcgtagattg gaaagaaaaa gcaagtgtat
     3841 cacgatttgt acaagctaac tacacacctt atgatggaga cgaaagcttc cttgcaggac
     3901 caacagagcg ttcacttcac atcaagaaaa ttgtagaaga aactaaagca cactacgaag
     3961 aaactcgttt cccaatggac actcgtccaa catctatcgc tgatatccct gctggattta
     4021 tcgacaaaga aaatgaagtt atcttcggta tccaaaacga tgaactcttc aaattgaact
     4081 tcatgccaaa aggtggtatc cgtatggctg aaactacttt gaaagaaaat ggatacgaac
     4141 cagacccagc tgttcacgaa atcttcacta aatatgtaac aacagttaac gacggtattt
     4201 tccgtgccta cacttcaaat attcgtcgcg ctcgtcacgc acacactgta actggtcttc
     4261 cagatgcata ctcacgcgga cgtatcatcg gtgtttacgc acgtcttgct ctttacggtg
     4321 cagactactt gatgcaagaa aaagtaaatg actggaatgc aatcaaagaa atcgatgaag
     4381 aaacaatccg tcttcgtgaa gaagtaaacc ttcaatacca agcattgcaa caagttgttc
     4441 gcctgggtga cctttacggg gttgatgttc gcaaaccagc gatgaacgtg aaagaagcaa
     4501 tccaatgggt taacattgct ttcatggctg tctgccgtgt gattaacggt gctgctacat
     4561 ctctaggtcg tgtaccaatc gtattggaca tctttgcaga acgtgacctt gctcgtggta
     4621 catttactga atcagaaatc caagaattcg ttgatgattt cgttatgaaa cttcgtacag
     4681 ttaaatttgc tcgtacaaaa gcttatgacc aattgtactc aggtgaccca acctttatca
     4741 caacttctat ggctggtatg ggtaacgacg gtcgtcaccg tgttactaag atggactacc
     4801 gtttcttgaa cactcttgac aacatcggta actcaccaga accaaacttg acagttcttt
     4861 ggactgacaa attgccatac aacttccgtc gctactgtat gcacatgagc cacaaacact
     4921 cttctatcca atacgaaggt gtaacaacaa tggctaaaga cggatatggt gaaatgagct
     4981 gtatctcatg ctgtgtgtct ccacttgatc cagaaaatga agaacaacgc cacaacatcc
     5041 agtacttcgg tgctcgtgta aacgttctta aagcccttct tactggtttg aatggtggtt
     5101 acgacgatgt tcacaaagac tacaaagtat ttgatatcga accaatccgt gacgaagttc
     5161 ttgaatttga atcagttaaa gcgaactttg aaaaatctct tgactggttg actgacactt
     5221 acgtagatgc cttgaacatc atccactaca tgactgatag gtacaactac gaagctgttc
     5281 aaatggcctt cttgccaact aaacaacgtg ccaacatggg attcggtatc tgtggatttg
     5341 ctaacactgt tgatacattg tcagctatca aatacgctac agttaaacca atccgtgacg
     5401 aagatggcta catctacgat tacgaaacaa tcggtgacta cccacgctgg ggtgaagatg
     5461 acccacgttc aaacgaattg gcagaatggt tgatcgaagc ttacacaact cgtctacgta
     5521 gccacaaact atacaaagac gcagaagcta cagtatcact tttgacaatc acatctaacg
     5581 ttgcttactc taaacaaact ggtaactcac cagttcacaa aggtgtatac ctcaacgaag
     5641 atggttctgt gaacttgtct aaacttgaat tcttctcacc aggtgctaac ccatctaaca
     5701 aagctaaagg tggttggttg caaaacttga actcactttc tagccttgac tttagttatg
     5761 cagctgacgg tatctcattg actacacaag tatcacctcg cgctcttggt aagactcgtg
     5821 atgaacaagt tgataacttg gtaacaatcc ttgatggtta cttcgaaaac ggtggacaac
     5881 acgttaactt gaacgttatg gacttgaacg atgtttacga aaaaatcatg tcaggcgaag
     5941 acgttatcgt acgtatctct ggatactgtg taaacactaa atacctcact ccagaacaaa
     6001 aaactgaatt gacacaacgt gtcttccacg aagttctttc aatggatgac gccttggatg
     6061 cattgagcta atcaagttct tgaataataa aaaggaaccc tcggtcaaac gactgagggt
     6121 tttgtgcttg ggatagtatg agcaattcct tcggcgcaat atgcaatgtt tttgggaagg
     6181 aatagtggac cgaatctgaa atataataga ttgaaactag aatagtacac ctttacttct
     6241 aaaacattct tagaaatcga tttgactgtc ctgatcgatt tgtcctattc ttatttcatt
     6301 ttactatagt ccgctgaaac ggctcaaaca gtgctagaaa ttgactggaa ttctctaagt
     6361 gatttgttcc gattttattt catttcatca taaaaataag atgactggct aattgacaat
     6421 catcttgttt gatactgtta ataaaattcg cgaagtttat cttgattttc tttaaaaaat
     6481 ttttctaacc aatccatacc ataagcataa ctaaaacctt ctaatagaac agagaggtca
     6541 atagtatcaa atcccatgtc ttttaaatat ttaaaggtat cgaatggtga atgaaagttt
     6601 ttgtatttaa taattgcacc aatatcttgc aaatcctgct ctctgatact catcatcttc
     6661 attcctaaca catactcaat agggactact aaaacggtca gattctcaaa tgagtacaag
     6721 gattcgcata aacttaaggg aggttgtttg ttcatatttg ctttgcaaca tgattgttga
     6781 gccataactc ttcgtggatg ttaagattaa actgttttcc tacacgagca ataatttcat
     6841 tgattttctg attttggtca taaaaagcat caacatcttg tgtggcacgt aaaccatgat
     6901 attctaagac ataaccataa ttgttaaagt cagattttcc tgaattaatt tcttatttag
     6961 ggcttggaag accggtttca ttttatccat gtttgtattt ctccatcaat ttttgaacat
     7021 tggttaactt agcaggttta tttaatgaaa tcacatattt atgagttgga gtatgctctt
     7081 gaaaggcata cttcaagcta attttttgaa aacgggttag ttctttggag tctagcaact
     7141 tttctacatc ttggtttgtt aaataagaat agtcttcaaa aataactttt cgcaaatagc
     7201 gaaaccaatg gcttgcgttg aattgtgatt gtttggatgc ctgtatcata taatcgtacc
     7261 aatccattgt cttcctccta taaaatttag tttatattat tgtagtttat attcaaaaat
     7321 gtagtttttc ttaattagct cgtatctata ggatgatact gaaaatcttc ttgttgcttt
     7381 aaatcacaat cgaaaaattc tgtttttcat cttagaaaag aatgtttaga aatgtaaaat
     7441 gaaccttttt tcttatccga aaaccttact aaagtatata atttaggcag tcaattctgt
     7501 atgataatgt ttgtactatc gtcgagtttt tgcttgattg cctaacgaga taaattttag
     7561 aagagttttc ggtgtgattt gacaagtttc tgactggaag gatagttaca ctagtattgt
     7621 ttattaaaat gagcagatag agaaaatttg gaatctattt gcttattatc aatcgttttt
     7681 ttagcttatt tgtcttagat tggtatagaa ctgagctatg gattaatctt cttctatctt
     7741 atcctgttcc taaatatgtt ggtagaaaaa tgaagcagtt gttacgagtg tctgtattgg
     7801 gaaaaatttt gtctatagaa ttctttaaat gatatgaagg ctaggaatgc caaaacactg
     7861 acatatttcg tttaaagtct atccagtctc ttcaattgta tttgtagaaa tgctatcagt
     7921 aatatattcg cgaacactat gatttacaac agtgtggtcg tacatctttg taactttatt
     7981 atacaacaac catttacagg tgtaaagttg agcagtgtct ttagtaaatt tagggacttg
     8041 ttttgtcata gttttgatac ctgtattcgt tgtttcatga gcatttgacg tttcttttca
     8101 tgtaggcatt tcaacaatta gaatgatatt tttccgagga tgaacttata tattgtgact
     8161 ttttagagtt atgatgcctc ttgatttgac taccgctatc aatttcatcc acttttacag
     8221 tttcatggtt ttatgaaccg aaacatctag gtacaggttt tagcatcaat tgattgtttt
     8281 tgagccatat gaagttgaaa cgtggagatg cttttcttgt gataacgccc tattcaaaga
     8341 ggaataaccg tttttggaga gagttcagta ctatgtggcg ctaaatacta tatgtaaaac
     8401 atatattaaa caagatttaa ctaaggagaa ttgtaaaaac aaaaatgaga atttcatata
     8461 aagtttattc taggagtatg tatcttgaat aaaaatcgtt atttaagttc agggttatga
     8521 tgaatgtttt tataataata aaatgcagct agaagaaaag ttattttaat ataaatcact
     8581 caacatagag agaaggcggt ttcctatatg gaagtcgtct tgttttcata ttgtctaaat
     8641 acgagatatc tactacaggt tatagttgat ttaaacaggt ctatagattt ctaatatatt
     8701 aaggtgaaat aatatcttgt aatacattgc tatgttctat gaaaaaagcg acgatagcta
     8761 atgcacaagc tcctatactt ccacgatgtt tgttgtaagg taaaatttca atttctatat
     8821 tacgagtaaa gggaacgaag tggagctggt cttggatttt atccctgact tcatgagtga
     8881 aaggttgata attaagcaat tgactgttga tatagatttt atcagcagga ttgatgagga
     8941 ggagatttgc aatagaagtg gctaataaat tgactccttt atcaatttgt tgacgtaaag
     9001 cggagtcgcc taaattataa gccgttaaaa gggtgtctaa atgaatgtct ttttcagtct
     9061 ttacaaggct ttttagtaca gttagttggg aatttttaaa taataattgg gcgtgtttga
     9121 ttaaccaagc atccgaaata tatgtttgta aacaaccttt ttttccgcat tcacaatatt
     9181 gcccattcaa ttcgacaatg gtgtgtccaa tttctccgat ataaggattt ttagaggctc
     9241 ctattttttc ttttgtgaaa aaggaagtgt aaatacctaa tccagcgtgt aggaaaataa
     9301 agttatcggg ggtattgtgt ggattaaaaa ggtattgtcc tatagccata caatcgatat
     9361 tattttttac aataaaagga aaattgaatc ttttaattac atttaataaa ttaaaagatt
     9421 cccatatggg gttgtttgta atgatacttc cggagtcttt gttataatgt ccaggtattg
     9481 ataagccaaa tccaagtaat tttgtttcca aagggacgta ctctatagct gtttttatca
     9541 tattggtaat ggtggaattg atttctgaaa taggataatc ttcattcaaa atttctgtct
     9601 cgaaaagagt tttcccttgt aagtcacata gactgagaaa gatacctagg acgtttattt
     9661 caatacctcc aacaacatac ggaatattat ctgtgataga aatagttttt ctacgtcttc
     9721 cagatccgga aaactcgcta aattcatcac cagtttcgta tatgagggac tgttcgctta
     9781 gctcttttat gatgttagtc gttgttgctg gagtaagtcc tgtttcatta acaatatctg
     9841 tacgggatgt tgctggattt cgatatagaa actccagtat agtggctcta ttttgtaaaa
     9901 aggctgattg ttttgtaatc atttgtttcc tcctttggtt tattttatat taaacataag
     9961 aaaaaatcaa ttaaaattat tattttatac aaagaaaaaa atattgtaaa aacaacaaaa
    10021 aatatattga caacgctttc tgttagtggt atatttaatt tataaaaaat aaaaaaagga
    10081 gttccggtga tgaacaatat tttagcgttt ttagaaacaa aagtcgctcc gtttggtgaa
    10141 aaagttggca accaacggca tttgaaagct attcgtgaag gatttatgat ggcaatgcct
    10201 ttgattttag tcggatcttt atttcttatt ctaatcagtt ggcctcaaga ggattttaca
    10261 aattggctga atagtgttgg attgctaagt atcttgacaa ctatgaatca gtcaacagta
    10321 gcgattatct ccttggtcgc ttgtttcggt attgcctaca ggttgtcgga aggatatggt
    10381 acagatggtc cgtcggcagg gatcatagcc ttatccagtt ttgtattgat ggcacctcgt
    10441 ttttcgagta tggtttatga taaaaatggg gagcaggtca agcagttatt tggcggcgca
    10501 ataccatttt ctagcctgaa tgcatcttct ttgtttatgg cgattactat tggattggtt
    10561 acagcagaga tttatcgtat gtttatccag cgcggaatta cgataaaaat gccaagtggt
    10621 gtcccagatg tggtaagtaa atcattttca gctcttttac ctggctttac tacttttgtt
    10681 ttgtgggctc tggtcttaaa aggtcttgaa gcggcaggag ttgcaggagg tctcaacgga
    10741 ctcctaggtg caattgttgg aacaccgctt aagttaattg caggaacgct tccaggtatg
    10801 attctatgtg ttattgtaaa ctcattcttt tggttctgtg gagttaatgg gggacaagtt
    10861 ttaaatgctt ttgtagatcc agtttggtta caatttacta cagaaaacca agaagctgtg
    10921 gctgcaggac aaacactcca acacattatt acattaccgt ttaaagattt atttgtattt
    10981 attggtggcg gtggagcgac tattggtctt gcgatttgtc tcttcctatt tagtaagagt
    11041 cgtgcgaata aaacattagg taagctagct attataccgt ctatttttaa tatcaataca
    11101 gctattctat ttacgtttcc aacagtttta aatccgatta tgctgattcc gtttattgct
    11161 actcctacaa tcaatgcctt aattacctat gtatcaatgg ctgtaggatt agtaccctac
    11221 acaacaggtg taatccttcc gtggacaatg ccaccgatca taggaggctt ccttgcgaca
    11281 ggagctagtt ggcgaggagc tctattacaa gttgttttga ttttggtttc tgtagcaatt
    11341 tattatccat tcttcaaaat tgcagataaa cgcaatcttg aaaaagaaaa agctactgtt
    11401 ggagggaaat aagatggtta tcagagtatt tgatcagcag aaaaatactt attctagctt
    11461 tgccttagag gaattaagtt actatataaa tcgggtcttt aagactgaca tagaacttgt
    11521 cgaggagaag gaagcggata tttttgtagg attagtcaat aaagaggata gaaaagacca
    11581 tgttcttatc tcattagaca agggtaaggg gagaattgag tctaatacaa ttgtaggttt
    11641 gcttattgga atttaccgaa tgtttcatga atttggggtt gtgtatacta gaccagggcg
    11701 cggacatgac tttgttccag agttacgatt tgaagatttt ttagataaag agctatctat
    11761 agatgaaaca gccagttact atcatagggg agtatgtata gagggagcag attcatttga
    11821 aaatatacta gatttcattg attggctacc taagattggg atgaacagtt ttttcattca
    11881 gtttgaaaat ccctattctt ttttgaaacg ttggtatgaa catgagttta atccatacct
    11941 aaataaagaa aaattctcaa atgaattagt acaagaattg agtgataggt tggataaaga
    12001 attgcaaaaa agaggtctta ttcatcatcg tgttggtcat ggatggacag gtgaggtttt
    12061 aggttactct tcaaaatttg gctgggaatc aggtcttagt atttcagagg agaagaaacc
    12121 ctatgtcgct gaaataaacg ggaaacgaga attatttaat acggctccga ttttaaccag
    12181 tctggatttt tcaaatccag atgtggcgga taagatggta gaaattatca aggattatgc
    12241 caagaaaaga cctgatgtta actacttaca tgtatggttg tcggatgctc gtaataatat
    12301 ttgtgaatgc gaaaactgta gacaagaatt ggtttcggat cagtatattc gtattctcaa
    12361 tcaattggat agggctttaa cgagtgaggg attagataca aagatttgtt ttctgcttta
    12421 ccatgagttg ttatgggcgc ctcagaaaga aaaattagat aatcctgaac gctttaccat
    12481 gatgtttgca ccgattacaa gaacatttga aatgagttat gcagatgtag attttgacaa
    12541 ttccatacct acgcctaaac cttatctgcg taataaaatt atacttccga attctcttga
    12601 ggaaaattta tcttatcttt ttgagtggca aaaaacattt aaaggagata gtttcgtata
    12661 tgactatcct ttagggcgtg ctcattatgg cgatttaggc tatatgaaaa ttagtcaaac
    12721 catttacaga gatgtatctt atctttctaa cctacatttg aacggttaca tttcgtgtca
    12781 agaattacgt gccggattcc ctcataattt tcctaattat gttatggggg aaatgctctg
    12841 gaagaagaca agaagttatg aagaattgat tgaagaatac ttttctgctt tgtatgggtc
    12901 aaattggcag tctgttgttg aatatttaga aaaattatcc agttattcct catgtgatta
    12961 ttttaatgca attggcagtc gtcaaaatga tgttttagcg aatcattatt atatagctta
    13021 caatctagct gataattttt tgccaattat tgaggaaaat atttctaagt tattaaatag
    13081 tcaaaaggat gaatggaaac agctcagtta tcatcgtgaa tatgttgtta agatggcgaa
    13141 ggctttatat cttcaagcaa ccggaaaaac aaggcaagct caagatgaat ggagaaatgt
    13201 gttgaattat atccgtgggc acgaattgct atttcaatct aatttggatg tttatcgtgt
    13261 aattgaagta gcaaaaaatt acgctggttt ccacttataa atcataagta tagaaaatga
    13321 accaaggtat tcagagaaga ttgatcctaa atattatgaa atttaaggat ttttaagata
    13381 tttagggtcg actttctatt tatatcgtag cgaagtcatt ttaataatga tgtgtaaaag
    13441 atggatcaag attgaggagg aagaaagatg aaatcaaaag aagaaataaa tatgcttggt
    13501 tttacaattg tcgcttacgc aggagatgca aggtcagatt tgatggatgc tttggcgttt
    13561 gcgagagatg gatattttga acaggcaaga gaattggttg agtctgcaaa cgactcaata
    13621 gtgtctgccc atcgagaaca gactaattta ttagcggagg aggcatctgg agataatttt
    13681 gaagtgagtt ttatcatgat tcatggtcaa gataccttga tgacaacgat gctattgtat
    13741 gatcaggtca agttttttat tgatgaatat gaacgaattc gaaagattga agaacatatt
    13801 ggtttgcaat gaggattagt catggaaaat ttacaggtta aagccttacc gaaggagttt
    13861 ttattaggag ctgctaccgc tgcttatcaa gtagagggtg caactagggt agatggcaaa
    13921 ggaacaaata tgtgggatgt ttatttgcaa gaaaacagtc cgttcttacc agatccagct
    13981 agtgattttt attatcgtta cgaagaggat ataactttgg cggcagaaca tggtttgcag
    14041 gctttgcgtt tatctatttc ttgggttcgt atatttcctg atatagatgg ggagcctaat
    14101 atattagctg ttcgttatta ccatagagtc tttcagtctt gcttaaaaca taatgtgatt
    14161 ccgtttgttt ctttacatca ttttgattcg cctcagaaaa tgttagaaac aggggattgg
    14221 ttgaatagag agaatattga tcgtttcata cgatatgctc gcttttgttt ccaagaattt
    14281 acagaagtca agcattggtt tacaatcaat gaactgatgt ctcttgctgc aggtcaatat
    14341 ataggaggtc agtttcctcc aaatcatcat tttcaattat ctgaagcaat tcaagcgaat
    14401 cataatatgt tgttggcgca tgctcttgca gtcctcgaat ttcatcaatt aggaattgag
    14461 ggagagatag gttgtattca tgctttaaag ccaggctatc ctattgatgg gcaaaaagaa
    14521 aatattttgg cagctaaacg gtatgatgtt tataataata aatttctatt agatggaact
    14581 tttttgggct actacagtga ggacacgctt tttcacttga atcaaatatt ggaagctaat
    14641 aattctagct ttattattga agatggtgat ttagaaatta tgaagagagc tgcagctctt
    14701 aatacgatgt ttgggatgaa ttattatcgt tcagaattta ttcgtgaata caaaggtgaa
    14761 aatagacaag aatttaattc aacaggaata aaaggacagt cttcttttaa attaaatgct
    14821 ctaggtgaat ttgtaaaaaa acctggtatt ccgacaacag attgggattg gaatatttat
    14881 cctcaagggt tatttgatat gttgcttcgt atcaaagaag aatatcctca acatccggtc
    14941 atttatttaa ctgaaaatgg tacagccctt aaagaagtta agccagaggg cgagaatgat
    15001 attattgatg acagtaagag aatccgttat attgagcaac atttacacaa agttttagag
    15061 gctcgagata gaggagtcaa tattcaaggc tattttatat ggtctttgca agatcaattt
    15121 tcttgggcga atggctacaa taagcgatat ggtcttttct ttgttgatta tgaaacacag
    15181 aagagatata ttaagaaaag tgctctttgg gtaaaagggc taaaacggaa ttaaggttag
    15241 cgatttgact gatgtttaat atattttaac tatgagctta aattttttac aggaggagtt
    15301 tttatggata agttagtcgc tgccattgaa aagcaacaag ggaaatttga aaaaatttct
    15361 actaataatt atatgatagc tattaaagat ggatttattg ctactatgcc tttaattatg
    15421 ttttcaagct ttttgatgat tattattatg attcctaaaa atttcggagt agagttaccg
    15481 agtccagcta ttgcctggat gaggaaagtg tatatgctaa ccatgggagt tttgggtatt
    15541 attgtttcag ggacagttgc aaagtcattg gctggaaatg ttaatagaaa aatgcctcct
    15601 ggaaaggtaa taaatgatac ttctgcaatg ttggcggcca tatgtggcta tcttgtatta
    15661 actgtaacgc ttgtagttga tgagaaaacg ggatctacaa gtttgtcgac aaactattta
    15721 ggatctcaag gattgataac ttcgtttgtc agtgccttta ttactgtaaa tgtttaccga
    15781 ttctgtatta agcgagacat tactattcat ttacctaagg aagttcctgg ggctatatca
    15841 caagctttta gagatatttt tcctttttct tttgttttac ttattagtgg tttgttagat
    15901 attgtatctc ggtttagttt agatgttcct tttgcccaag tatttcaaca actattgact
    15961 cctattttta agggggcaga atcatatcct gctatgatgt tgatttggtt tatgtgtgct
    16021 ttgctttggt ttgttggaat tcatggacca tctattgtct tacctgctgt tacagcttta
    16081 caactgagca atatggaaga gaatgctcaa cttcttgcaa atgggcagtt cccttatcat
    16141 tctttaacac ctaatttcgg gaattatatc gctgctattg gaggaacggg ggctaccttt
    16201 gttgtaccat ttattttgat tttctttatg cggtctaaac aattaaaatc ggtaggtaaa
    16261 gctacaatta ctcctgtttt atttgcggta aatgaacctc ttctatttgg tatgcctgtt
    16321 attttgaatc cctatctttt tgtccctttt ttgatgactc caccagtgaa tgtatttcta
    16381 ggaaaggtat ttattgattt ctttggaatg aatggatttt atatccagtt accttgggcc
    16441 tttcctggtc ccttgggatt gttaattgga acgaattttc aacttatctc ctttgtattt
    16501 ttatctttga tgttagttgt cgacatattg atttatttgc cattctgtag agcgtatgat
    16561 agacagttac tggtgaaaga agatattgca agctcaaatg atattatttt agaggaggat
    16621 acaagtgaaa taatgcctgg tgagatagat gtaataaaaa gtaaggagtt gaaagtactg
    16681 gttctttgtg cagggtctgg aacaagtgcg caattagcca atgcaattaa cgagggcgct
    16741 caattagcag aagttagagt gattgcgaat tcaggagcgt acggagctca ttatgatatt
    16801 atgggtgttt atgatttaat tattctggcc ccacaagttc ggagttatta tagagagatg
    16861 aaggtggatg cagaaagatt agatattcag atagttgcta ccagaggaat ggaatatatt
    16921 catttaacaa agagtccaag taaagcctta caatttgtat tggagcatta ccaagctgtg
    16981 tagtaagttt ttccatcttt tatttgagta aagattttgc ttacagatag gcttggattt
    17041 aaaaacgttc cccctttttt aatataagaa tccctctttc acaattgtaa aaagagggat
    17101 tttgtatttt atctcttaga ccaagttctc ttcataaaga gaaggaggat tgggtaaatc
    17161 tccaagcgcc ctgcaatcat tgcaaaggat aggagaattt ttgagatggg actaaagatt
    17221 gagaaactag aagtggttcc tagaataggc ccgatattat tgaaacagct aaagacagcg
    17281 ctggtcacga ccagaaaatc attgctatct aggctgacaa taaagataag cgctagcaaa
    17341 atcatagcat agatgacaaa gtacttgaga atcttatgct gggtatcttt gtcaatcacc
    17401 gttttattaa catggagggt caaaacacgg tggggcgata ggattgacaa aatttggttt
    17461 ttggcaattt ttgaaaggat gaggcctcga ataatcttga gtccacctgc agttgatcca
    17521 gcagagccac cgattgccat gaggaaaagg aggataaact gggagaagag gggccagttg
    17581 gtaatatctc catatccaaa accagttgtt gtaatgatgt tggaaacctg gaagaaggtc
    17641 atttcaaagc tctttgaaaa ccctgggtag aggtagaggg tgttgaggct aatcaagcct
    17701 gtagaaacca gtacaatgac caagtaagcc ctaagctctt catctccaaa gaaggccttg
    17761 atgcgacgga gcatgaggta gtagtagagg ttgaaattta ctccaaaaac cagaactccg
    17821 atactgacca gataggtaat cagtgagctg ccatagtggg caattccgtc gttatagacg
    17881 gtaaagcctc cagttcccgc tgtccccata gcaatgacaa aactatcgta gagaggcata
    17941 ccagctagat aatagatgat gacaaagagg gagaagagag ctagataaag gagatagaga
    18001 atctgggcag tgttttttag tttggataca accttgccaa aaacaggacc tggaacctca
    18061 gccttcatca cctctaggtg gctatttttg gcattgtcca taatagcaag tgcaaaaaca
    18121 agcactccca tccctccaat caagtgggta aaacttcgcc agaagaggag ggaacgactg
    18181 agaactgaaa cgtcgttcaa aatacttgct ccagtagtcg taaagccgga actaatctca
    18241 aaaaaggcat caataaggct ggggatttgc ccagaaaaga caaaggggag accaccaaag
    18301 aaagaccaaa ggatccaaca gagggcaacg atcaagactc cctccttggc ataaatccgt
    18361 tgattttttg gcttctgtaa actccctgaa ccgcctaaca atacgagaat ccctatggtc
    18421 gaaaagaggg ctgtaaagac ttggctcgat tcacggtaat agacagcgat agccacagga
    18481 accaagagga gaacagcttc aatcaaaagt aactttgaaa ggaggtaacg aatcatactt
    18541 ttattcattt cttacctcgc aatcaagtca taaatcttgg tgatgtttgg caacaaggtt
    18601 gttactagga gcttgtctcc aacttccaac atatcctccc cagttgggaa aatagtcttg
    18661 ccctttcgaa taatggctgc aataagaacc ccttttttca atttcagttg agaaagaggt
    18721 ttggcagtca ttttattggc ttccttgata tggaattgca gggtttcgat ttggccattg
    18781 gctagatggt gcatggcttg aaggtctgaa tactgggcat taactcgacc acgaataaag
    18841 tgcataatcg tatctacagc gatgctttta ggtgtgatga tacttgaaaa atcaggcgca
    18901 ttgataatct cgaggagact ggtacgattg accttagtaa tatttttctg tacacctacc
    18961 ctgtcaagga acatagatgt aatcagattt tcctcatcga ctcctgttag agtcgcaacg
    19021 gcatcatagt gttgagcact ttcttccagc aggatatctt ttgcggttcc atctccttga
    19081 acgatgtaga gatttgggaa tttctcgcta aagaagctgg cgatttcagg attgatttca
    19141 atgacttttg tatcgatacg actatctttg agaataccaa gtagataata ggcaattcta
    19201 cctgccccaa cgatgagaag gctcttcacg gcgcgtgatt taaaataatt atggaagagt
    19261 atcatatcga cacggttacc agtgacaaag attctatctt tatcctgtac agtcatgtca
    19321 ccgcttggaa tgataatttg atgatccctc tctatcgcac agacaatgac attaccaaat
    19381 tttttacgaa aatcagaaat gggcatttgg caaagaccgc tggtggactt gacgacaaat
    19441 tccatgaggc taacgcgtcc accagcaaag cgttcgacag acagggcgtt ggggaagtca
    19501 atgatattcg cgatagcacg ggcagccaag agctcaggat taacgataag agaaaaaccg
    19561 agaatattct tttccttgaa ataagagtta gaatattcag ggttccgcac ccgaacgata
    19621 gtttctttag ctcccatttt cttggctaga actgctgcaa tcatgttgac ttcatcgtgc
    19681 tcagtcaggg cgataaagat atcacaatct tggacgctgg cttgctcaag aatggcaaaa
    19741 tcggccccgt taccaaggat accaatgata tcaaagcgac tgacaatatg attgagaaca
    19801 gcttcgtctt gctcaatcag caaaacatca tgcttttctg caaccaagga gcgacagagg
    19861 gcaaaaccaa cttttccccc tccgacaagg ataattttca taataaaacc tactttttca
    19921 tgatgtaact atcataccct ttttcaagaa aaaatgcacc tactagctaa taacaagagc
    19981 ttttagtgaa aattcgctat aagataaaac tataccctaa ccaattgaaa tagctattag
    20041 cgactttctc tgaaatatgg tatgataaag gatatacaag gagataaaat gaataataat
    20101 ttactggtat tacaatcaga ctttggtctg gttgatggtg cggtatcggc tatgattgga
    20161 gtggctttag aagagtctcc aaccttaaaa atccatcact tgacgcacga tatcacgcct
    20221 tataatattt ttgaggggag ctatcgtctc tttcagacgg tggattactg gcctgaggga
    20281 acgacgtttg tatcggttgt cgatccaggt gtcggttcga aacgtaagag tgtagttgcc
    20341 aagactgcaa aaaatcaata cattgtcacg ccagataatg ggacgctttc ctttatcaag
    20401 aaacacgttg gcattgtagc cattcgtgag atttctgagg tggccaatag gcgtcaaaac
    20461 acagagcatt cttatacctt ccacggtcgt gatgtctatg cctatactgg tgctaaactg
    20521 gccagtggtc acattacttt tgaggaagta gggccagagc tcagtgtgga acagattgta
    20581 gagcttccag tcgtagcgac catcatagaa gatcatctgg tgaagggagc cattgatatt
    20641 ctggatgtgc gtttcggttc gctttggacc tctatcacac gggaagaatt ttacaagttg
    20701 gaaccagaat ttggtgatcg ttttgaagtg accatctatc atgctgatat gctggtctat
    20761 caaaatcagg ttgtctatgg caaatcattt gcagatgtga gaattgggca acccatcctt
    20821 tacatcaact ctctctatcg tttaggtttg gctatcaacc aaggttcctt tgccaaggcc
    20881 tataatgtag gtgtcggttc atcttggacc attgaaataa agaaaataga aggataaaat
    20941 aggagaatag tatggaaatc aaatttacaa ttaaacaagt tgttgctgtc ggaattggcg
    21001 ctgccctctt tgtcgtcatc gggatgatca acattccaac ccctgttcca aatacaagca
    21061 tccagcttca gtatgcggta caagcgctac tttctattat ttttggaccg attatcggtt
    21121 tgcttgttgg gttgattggt catgcaatca aggactctct tgttggttat ggtctatggt
    21181 ggacttggat tatcgctagc ggactctttg gtttagttgt gggacttttt agaaagtacg
    21241 ttcgcgtgat caatggtgtt tttgactgga aagatattct tatttttaac ctcattcaac
    21301 tacttgcaaa tgcccttgtt tggggtgtct tggcaccact tggagatgtt gtgatttatc
    21361 aagaagcggc agaaaaagta tttgcacaag gaattgttgc gggaattgcc aatggtgtat
    21421 ctgtagctat tgcaggaact cttctcttac ttgcctatgc aggaacccaa actcgtgcag
    21481 gaagtttgaa aaaggactaa tactcaatga aaatcaaaga gcaaactagg aagttagccg
    21541 caggttgctc aaaacagtgt tttgaaattg tggata
//
LOCUS       DAVBIC010000040        21414 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.040, whole genome shotgun sequence.
ACCESSION   DAVBIC010000040 DAVBIC010000000
VERSION     DAVBIC010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21414)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21414)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21414
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.040"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            66..287
                     /locus_tag="VQ664_001484"
     CDS             66..287
                     /locus_tag="VQ664_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2789632.1"
                     /translation="MYRRLRDLREDHDLTQKQIAKILSFTNSAYAKIERGEHTLTADV
                     LVTLSNFYDVSTDYLLELTDFPDKIRFRK"
     gene            804..1043
                     /locus_tag="VQ664_001485"
                     /pseudo
     CDS             804..1043
                     /locus_tag="VQ664_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558195.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            1187..2416
                     /locus_tag="VQ664_001486"
     CDS             1187..2416
                     /locus_tag="VQ664_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HET2789633.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGVTIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSAASVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            2436..5132
                     /gene="ppc"
                     /locus_tag="VQ664_001487"
     CDS             2436..5132
                     /gene="ppc"
                     /locus_tag="VQ664_001487"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HET2789634.1"
                     /translation="MSLQKLENSSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAKTLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATNLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDIYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYEIILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     misc_binding    5215..5432
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            5545..6549
                     /locus_tag="VQ664_001488"
     CDS             5545..6549
                     /locus_tag="VQ664_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET2789635.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEAQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNVTGVSDHNPAQQQ
                     IELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTIKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     gene            6618..7484
                     /locus_tag="VQ664_001489"
     CDS             6618..7484
                     /locus_tag="VQ664_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2789636.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGRMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            7481..8239
                     /locus_tag="VQ664_001490"
     CDS             7481..8239
                     /locus_tag="VQ664_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2789637.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFERDFITILGGN
                     GAGKSTLFNTIAGTLSLTSGTIRILGEDLTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLLPRRLTSYKDEFQATIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRIIQDLNQEEKAKMKISDYYQLFE"
     gene            8329..10089
                     /gene="dnaG"
                     /locus_tag="VQ664_001491"
     CDS             8329..10089
                     /gene="dnaG"
                     /locus_tag="VQ664_001491"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HET2789638.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVTFMEAVQILGQRVGIEVEKPLYSEQ
                     KPASPHQALYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDANQFVDTFHNRIMFPLTNDQGKVIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKKSSGKTSEIYLMEGFMDVIAAYRAGI
                     ENAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAAILKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFIEKIAPLI
                     VQEKSIAAQNSYIHILADSLASFDYTQIEQIVNESRQVQRQNRMERISRPTPITMPVT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            10092..11201
                     /gene="rpoD"
                     /locus_tag="VQ664_001492"
     CDS             10092..11201
                     /gene="rpoD"
                     /locus_tag="VQ664_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HET2789639.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            11215..11544
                     /locus_tag="VQ664_001493"
     CDS             11215..11544
                     /locus_tag="VQ664_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HET2789640.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            11659..12702
                     /gene="cpoA"
                     /locus_tag="VQ664_001494"
     CDS             11659..12702
                     /gene="cpoA"
                     /locus_tag="VQ664_001494"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HET2789641.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPAVLKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            12718..14043
                     /locus_tag="VQ664_001495"
     CDS             12718..14043
                     /locus_tag="VQ664_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HET2789642.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGILIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLAAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGALYYGE
                     HDLAGAILEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFRTVLYLPQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            14074..14250
                     /locus_tag="VQ664_001496"
     CDS             14074..14250
                     /locus_tag="VQ664_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HET2789643.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVQVIWGVLTCCYGAGIVA
                     YIILWIIAPVATDY"
     gene            14309..14443
                     /locus_tag="VQ664_001497"
     CDS             14309..14443
                     /locus_tag="VQ664_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HET2789644.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            14507..15817
                     /gene="obgE"
                     /locus_tag="VQ664_001498"
     CDS             14507..15817
                     /gene="obgE"
                     /locus_tag="VQ664_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HET2789645.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEEFKKKLSENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            15827..15985
                     /locus_tag="VQ664_001499"
     CDS             15827..15985
                     /locus_tag="VQ664_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789646.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
     gene            17035..18294
                     /locus_tag="VQ664_001500"
     CDS             17035..18294
                     /locus_tag="VQ664_001500"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HET2789647.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGASVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
     gene            18310..18861
                     /locus_tag="VQ664_001501"
     CDS             18310..18861
                     /locus_tag="VQ664_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2789648.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLFIITHLENEASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            18854..20131
                     /locus_tag="VQ664_001502"
     CDS             18854..20131
                     /locus_tag="VQ664_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HET2789649.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIDRLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFLVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            20147..21007
                     /locus_tag="VQ664_001503"
     CDS             20147..21007
                     /locus_tag="VQ664_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HET2789650.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
BASE COUNT         6551 a         3678 c         4805 g         6380 t
ORIGIN      
        1 ccagttagga cactttgaat gatttcttag ttttatatat tatacttttc tcaggagaaa
       61 gctagatgta cagacgtttg agagatttga gggaagatca cgatttgacc caaaaacaaa
      121 tagctaaaat actttcgttt acaaactcag cttatgctaa aattgaacgg ggtgagcata
      181 cgttaacagc agatgtattg gtaactctct caaactttta cgatgtcagt acagactacc
      241 tattggaatt gacagatttt cctgataaaa ttcgctttag aaaataatct cctcaatttc
      301 atagagtgtg aaaatgagga gattttttat ttgttctttg aaaattaaat agtccaaaat
      361 ggtactttcc tcatttgtgg agcaaatttg aatggctcgc catgataaga gcgattttaa
      421 agccatcaat aaaatagagc gatactttat atgccatgat acaaatgata tacaatgata
      481 cttctgaccg ttcaggctgc catcgtaaaa gagcagcaag tgaaattctt atgatgactt
      541 catcagtcat gccacgttga atgtgtgagt ttgttagaga aacgcaatta atcctcaaaa
      601 ggttccccga accttttgag ttccacagac gcatcacgtg gagtgtgtaa gcttgttgct
      661 aaaagcgtaa aaaccttgga acgaaaggaa taatagactt cctgcgaaac aaaaatacaa
      721 tacaataaaa ctatggatga tgaagcaagt aaacaattaa gcgatagccg tttcaagagc
      781 cttgtaggtg ttcagcgcac gagatgttag ctgtgttaaa aacagcttat caacgcaacg
      841 taaacgcgca aaaggtggac gaaaaaccaa attaagccta gacgatctcc tcatggtaac
      901 tattcaatac atgcgagaat agcgcactta tgaacaaatt gcggctgatt ttggcattca
      961 cgaaagcaac ataattagtc ggaggtcaat ggattgaagc aactcttatt caaaatggtt
     1021 ttacgatttc aaattctgcc ttaattctgt aaaaacagta aaattcgaag gattgtaagg
     1081 taagagtttt tttctttctg aaaaaatggt ataatagcaa tcaaaactag aaaataaaac
     1141 ggaatttgga acagatttgt ctgtatccta gtagagtggt gatactatga agattagtaa
     1201 gaggcactta ttaaattatt ccatcttgat tccctacttg cttttatcta ttttgggctt
     1261 gattgtggtc tattcgacca ccagtgctat tttaattgaa gaaggcaaga gcgccttgca
     1321 gttggttcga aaccaaggaa tcttttggat tgttagtttg atactgattg ccttaattta
     1381 taaattgaga ctagattttt tgagaaatga gcgactaatc attttagtta tattaataga
     1441 aatgctttta ttgttcttgg ctcgttttat tggtatttca gtaaacgggg catacggttg
     1501 gatttcggtt gcaggagtaa ctattcagcc agctgagtac ttaaaaatca ttattatttg
     1561 gtatttagct caccgattct ccaaacagca agaagaaata gctacttatg attttcaagt
     1621 tttgactcaa aatcaatggc ttccccgtgc ttttaatgat tggcgattcg ttctcctagt
     1681 tctgattgga agtttgggaa ttttccctga tttaggaaat gcgactattt tagtcttggt
     1741 ttccttgatt atgtatacag ttagtggaat cgcttatcgc tggttttcaa ccattctggc
     1801 gctcgtatct gccgcttctg tctttgtctt gaccactatc agcctaatcg gtgttgagac
     1861 cttttcaaaa attccagtat ttggctatgt agccaaacgc tttagtgcct tttttaatcc
     1921 ttttgccgat cgtgctgatg caggtcacca gttagctaat tcttattttg ccatggtcaa
     1981 tggtggttgg tttggtctag gtcttggaaa ctcgattgaa aaacgaggtt atttgccaga
     2041 agctcataca gactttgtct tttctatcgt gattgaagaa tttggctttg ttggtgccag
     2101 tcttatttta gctctcttgt ttttcatgat tttgcggatt atcttggtcg gtattcgagc
     2161 ggagaatcct ttcaatgcca tggttgcact cggtgtcgga gggatgatgt tggttcaggt
     2221 atttgtcaat atcggaggga tttcgggctt gattccatct acaggagtaa ccttcccctt
     2281 cttatcccag ggtggaaata gtcttctagt cttatcagtg gcagtagcct ttgtcttaaa
     2341 tattgatgcc agtgaaaaac gcgctaagtt gtaccgagaa ttggaaaatc aaccaatgaa
     2401 ccttctgttg aagtaggata aagaaaggat agtttatgtc tcttcaaaaa ttagaaaatt
     2461 ctagtaataa aagtgttgtg caagaagaag tcttgattct aacagaatta ctggaagata
     2521 ttactaaaaa tatgcttgcc ccagagacct ttgaaaaaat aatacagttg aaagaattat
     2581 caacgcagga agattatcaa ggtctaaacc gtctagtgac tagcttatca aatgatgaaa
     2641 tggtctatat ttcacgctat ttctctatct tgcctctttt gattaatatt tcagaggatg
     2701 tggatttagc ttatgaaatc aatcatcaaa ataatattga tcaggactat ttaggtaaat
     2761 tatctacaac gattaaattg gtagcagaaa aggaaaatgc cgttgagatc ctagaacact
     2821 tgaatgttgt tccggttttg acagcccatc caacacaagt gcaacgcaaa agtatgttgg
     2881 atttaacaaa tcatattcat agtcttttgc gtaaataccg tgatgttaag ttggggttga
     2941 tcaataaaga taaatggtac aatgatttgc gtcgttacat cgaaattatc atgcagacag
     3001 acatgattcg tgagaaaaaa ttaaaagtga ctaacgaaat cacgaatgct atggaatatt
     3061 ataacagctc ctttttgaaa gctgtacctc atttgacgac ggagtataag cgcttagcgc
     3121 aagcgcatgg tctgaattta aaacaggcta aaccaatcac catgggtatg tggataggtg
     3181 gtgaccgtga tggaaatcca tttgttacag caaagacctt gaagcagtct gcactcactc
     3241 aatgtgaagt catcatgaac tactatgata aaaagattta ccaactttat cgtgaatttt
     3301 ctctttcaac tagcattgtc aacgtcagca agcaagtcag agaaatggct cgtcaatcca
     3361 aggataactc gatttaccgc gaaaaagagc tttaccgtcg tgccttgttt gatattcaat
     3421 caaaaattca ggcaactaaa acctatctga ttgaggatga agaagttggg actcgttatg
     3481 aaaccgccaa tgatttctac aaggatttga ttgccattcg agattctcta ctagagaata
     3541 agggcgagtc cttgatttca ggtgattttg tggaattatt gcaggcagta gagatatttg
     3601 gtttttacct agcatcaatt gatatgcgac aagactctag cgtctatgaa gcctgtgtgg
     3661 cagaactctt gaaatcagca ggaattcatt ctcgttatag cgagttgagc gaagaagaaa
     3721 agtgtgacct tcttttgaaa gaattagaag aagatccccg aattctttct gcgactcacg
     3781 cagaaaaatc agaattatta gcaaaagaac tagctatttt taagacggct cgtgttttga
     3841 aagataagtt gggagatgat gtcatccgtc agaccatcat ttcacatgca accaaccttt
     3901 ctgatatgct agaattagct attctgttaa aagaagtagg actggtggat acggaaaggg
     3961 cgcgtgttca gattgttccc ctttttgaaa caattgaaga cttggatcat tcagaggaaa
     4021 caatgagaaa atatctttct cttagccttg ccaaaaaatg gattgactca cgaaataact
     4081 accaagaaat catgcttggc tactctgaca gtaataaaga tggcggttac ttgtcatcat
     4141 gttggaccct ctacaaggct caacaacaat tgactgctat tggagatgaa tttggcgtta
     4201 aggttacctt cttccatggt cgtggtggta ctgtcggtcg tggtggtggg ccaacctatg
     4261 aagccattac atctcaaccg ctcaagtcta tcaaggatcg tatccgtttg acggagcagg
     4321 gtgaagtaat tgggaataaa tacggtaaca aagacgccgc ttactataac cttgaaatgc
     4381 tagtatcggc agctattaac cgtatgatta ctcagaagaa gagcgatacc aataccccaa
     4441 atcgttatga agccattatg gatcaagtag tggaccgtag ttacgatatc taccgtgatt
     4501 tggtctttgg taatgagcat ttctatgatt atttcttcga gtcaagtcca atcaaggcta
     4561 tttcaagttt taatattggt tctcgtccag ccgctcgtaa gactattact gaaatcggtg
     4621 gtttgcgtgc catcccttgg gtattctcat ggtcacagag tcgtgttatg ttccctggat
     4681 ggtacggggt tggttcaagc ttcaaggaat ttatcaataa aaatccagag aatattgcta
     4741 tcttacgaga tatgtaccaa aattggcctt tcttccaatc gcttctttca aatgttgata
     4801 tggttttgtc aaaatcaaat atgaatattg cttttgaata tgctaaactt tgtgaagacg
     4861 agcaagttaa ggccatctat gagattattt taaatgaatg gcaagttact aagaacgtta
     4921 tcttggctat tgaaggacat gacgaactct tagctgacaa tccatatcta aaagctagtc
     4981 tggattaccg tatgccttac tttaatattc tcaactatat tcagttagag ttgattaaac
     5041 gccaacgtcg tggagaattg tccagtgatc aagaacgatt gattcatatc accatcaacg
     5101 gaattgcgac aggattgcgt aattcaggtt gataattttc aagagtgaat gctaaaagtg
     5161 aatatcaaaa aaattctaat agactattga caagtagttt aaaaatgata taatttaacc
     5221 attcagaaaa gtaatcatac aaacttttta gagagtctgt ggtagctgaa aacagataag
     5281 tggcgatgat gaaaattggg ctgaatgcta tttagaattt gaaattataa aaattcggta
     5341 agcacacctt acagtgcatc tcgttattgc gagactgagc gatagggaaa ttccctataa
     5401 ttgaggtggt accgcgcatc gacgtcctca cacaagtttt ttgtgtgagg atttttttga
     5461 tggaggttag tatggaaaga aaacgatggc gtcgcttgtt tagataagtg aaatatgtta
     5521 aaggaaataa aaaggagaaa cagaatgaaa aataaacgtt taattggaat tattgctgca
     5581 ttagcagtct tagtagcagg aagcttgatt tattcttcaa tgaataaatc agaagctcag
     5641 aataataagg atgagaagaa aataaccaag attggtgtgc ttcaatttgt gagccatcca
     5701 tcccttgatt tgatttataa agggatccaa gatggacttg cagaagaagg atataaagat
     5761 gatcaagtta aaattgattt tatgaactca gaaggtgatc aaagtaaggt tgcgacaatg
     5821 agtaaacaat tggttgcaaa tgggaatgac cttgtggttg gtattgcaac accagcagcc
     5881 caagggttgg ctagtgcaac aaaagaccta ccagttatca tggccgctat tacagaccca
     5941 attggtgcta acttggttaa agatttgaaa aaaccaggtg gtaacgttac aggggtatct
     6001 gaccacaatc cagctcaaca acaaattgaa ctcatcaagg ctctgacacc gaatgtgaaa
     6061 acaatcggag ctctttactc aagtagcgaa gacaattcaa aaacacaggt tgaagaattt
     6121 aaggcttatg ctgaaaaagc aggtctgaca gtggaaacat ttgcagttcc ttcaacaaat
     6181 gaaattgcct caactgtcac tgttatgact atcaaggtag atgctatttg ggttccaatt
     6241 gataacacca ttgcatcagg atttccaacg gttgtctcta gcaatcaaag ttctaagaaa
     6301 ccaatttatc ccagtgcgac agctatggta gaagtaggtg gtttggcatc agttgtaatt
     6361 gaccaacatg accttggtgt ggcaacaggt aaaatgattg tgcaagtctt gaaaggtgca
     6421 aaaccagccg ataccccagt caatgtcttt tcaactggta agtcagtcat caataaaaaa
     6481 atagcacaag aactaggtat tactattcct gagtctgttc tcaaagaagc aggacaagtc
     6541 atcgaataaa taaggtaggg aggaggagac tcttcccatt ttttaaaaag atgaatatag
     6601 aaaggattaa ataaaatatg attgtttcca ttatttctca aggatttgtc tgggctattc
     6661 taggtctggg aatctttatg acatttagga ttttaaactt tccagatatg acgacagaag
     6721 gttccttccc tcttggggga gctgttgctg tcactttgat aaccaaaggc gtgaacccat
     6781 ttttagcgac acttgttgct gtaggagcag gttgtttggc tggaatggca gcaggccttc
     6841 tttatacaaa agggaagatc ccaaccttgc tctcagggat tttggtgatg acttcttgtc
     6901 actcaatcat gctcttgatt atgggacgtg cgaatttagg cctgcttgga accaagcaaa
     6961 ttcaggatgt tttgcctttt gattcggatt tgaatcaact cttgacaggt ctcatctttg
     7021 tgagcattgt tattgctctc atgctctttt tcttggacac taaactcgga caagcctata
     7081 ttgctacagg ggataatcct gatatggcta gaagtttcgg gattcatact ggacgcatgg
     7141 agctcatggg cttggtctta tcaaatggtg tgattgccct tgcaggtgcc ctcattgctc
     7201 agcaagaagg ctatgccgat gtgtctcgag ggatcggggt tatcgttgtg gggcttgcaa
     7261 gtttgattat tggagaagtt attttcaaga gtttgagctt ggcagagcgt ttggttacta
     7321 tcgttgtagg ttctatcgct tatcaatttt tagtgtgggc agttatcgca cttggcttta
     7381 atacaagtta ccttcgttta tacagtgcct tgattttagc agtctgcctc atgattccaa
     7441 catttaagca aacaatcttg aaaggagcca agttaagcaa atgacagcaa ttgtagaatt
     7501 aaaaaatgca accaaaattg ttaaaaatgg ctttgatgaa gaaaagatta ttttaaatga
     7561 tgtttcctta gaaatttttg aacgggactt tatcacgatt ttgggcggaa atggtgctgg
     7621 aaaatcaacc ctctttaaca ctatagcagg gaccttatca ctaactagtg gaactatccg
     7681 tattttaggt gaagatctca ctaagttttc acccgagaag cgtgccaagt acctgtctcg
     7741 tgtcttccaa gatccaaaga tggggacagc tccccgtatg acggtcgctg aaaatctttt
     7801 aatcgccaag tttcgtggtg agaagcgtgg attgttacca cgacgcttga ctagctataa
     7861 ggatgaattt caggcaacca ttgaaaaagt aggaaatggt cttgagaaac acttgaatac
     7921 accgattgag ttcttatcag gtggacaaag acaggctttg agtctcttga tggcaacctt
     7981 gaagcgacct gaattactcc tgttagatga gcatactgct gccctggatc caaagactag
     8041 tgttgctttg atggaattga cagatgaatt tgttaagaaa gatcagctaa cagcccttat
     8101 gattactcat catatggaag atgctctcaa atacggcaat cgcttgattg tcatgaaaga
     8161 aggacggatt atccaagatt taaaccaaga agaaaaagca aaaatgaaaa tctctgatta
     8221 ttatcaactc tttgaataaa gtagggaaaa tgagtgaaat ggtttacttt ttttctgaaa
     8281 taaagtatac tatataaagt aaactatgat aacatggagg tattgtgtat ggttgacaaa
     8341 caagtcattg aagaaatcaa aaacaatgcc aacattgtgg aagtcatagg agatgtgatt
     8401 tctttacaaa aggcaggacg gaactatcta gggctctgtc cttttcatgg tgaaaaaaca
     8461 ccttctttca acgttgtaga ggacaagcag ttttaccact gttttggttg tggtcgctca
     8521 ggtgatgtct ttaaattcat cgaggagtac caaggggtta cctttatgga ggctgtccaa
     8581 atcttaggtc agcgtgtcgg gattgaggtt gaaaaaccgc tttatagtga acagaagcca
     8641 gcctcgcctc accaagctct ttatgatatg cacgaagatg cggctaaatt ttaccatgct
     8701 attctcatga caacgactat gggcgaagag gccagaaatt acctttatca gcggggtttg
     8761 acagatgaag tgcttaaaca tttttggatt ggtttagcac ctccagaacg aaactatctc
     8821 tatcaacgtt tgtctgatca gtatcgtgaa gaggatttac tggattcagg cctgttttat
     8881 ctctcggatg ccaatcaatt tgtagacacc tttcacaatc gcattatgtt tcccctgaca
     8941 aatgaccaag gaaaggtcat tgccttctca ggtcgtatct ggcaaaaaac ggattcacaa
     9001 acttctaagt ataaaaacag ccgatcgact gcaattttta acaaaagtta cgaattatat
     9061 catatggata gggcaaaaaa atcttctgga aaaactagtg agatttacct gatggaagga
     9121 ttcatggatg ttattgcagc ctatcgggct ggaatcgaaa atgctgtggc gtcgatggga
     9181 acggccttga gtcgagagca tgttgagcat ctgaaaaggt taaccaagaa attggttctt
     9241 gtttacgatg gagataaggc tgggcaagcc gcgatattga aagcattgga tgaaattggt
     9301 gatatgcctg tgcaaatcgt tagcatgcct gataacttgg atcctgatga gtatctacaa
     9361 aaaaatggtc cagaagactt ggcctatcta ttaacaaaaa ctcgtattag tccgattgag
     9421 ttctacattc atcagtacaa acctgaaaac agtgaaaatc tgcaggctca gattgagttt
     9481 attgaaaaaa tagctccctt gattgttcaa gaaaagtcca tcgctgctca aaacagctat
     9541 attcatattt tagctgacag tctggcgtcc tttgattata cccagattga gcagattgtt
     9601 aatgagagtc gtcaggtgca aaggcagaat cgcatggaaa gaatttccag accgacgcca
     9661 atcaccatgc ctgtcaccaa gcagttatcg gctattatga gggcagaagc ccatctactc
     9721 tatcggatga tggaatcccc tcttgttttg aacgattacc gtttgcgaga agactttgca
     9781 tttgctacac ctgaatttca ggtcttatat gacttgcttg gccagtatgg aaatcttcct
     9841 ccagaagttt tagcagagca gacagaggaa gttgaaagag cttggtacca agttttagct
     9901 caggatttgc ctgctgagat atcgccgcag gaacttagtg aagtagagat gactcgaaac
     9961 aaggctctct tgaatcagga caatatgaga atcaaaaaga aggtgcagga agctagccat
    10021 gtaggagata cagatacagc cctagaagaa ttggaacgtt taatttccca aaagagaaga
    10081 atggagtaat aatggcaaca aaacaaaaag aagtaacaac atttgacgta caggtagcag
    10141 aatttatccg taatcataag caaaaaggga cagcaacaga tgatgaaatc aatgcaagtc
    10201 tggttattcc ttttaccttg gacgctgatg ggattgaaga tctcttgcaa cggattcagg
    10261 atgcagggat ttctatcaca gataacgaag gaaatccaag tgcgcgtgtt cttagcaatg
    10321 aagaagaacc agaactcagc gatgaggact tgattggatc aacttctgct aaggtcaatg
    10381 accctgtccg tatgtacttg aaagaaatag gggtcgttcc tctcttgacc aatgaagagg
    10441 agaaagagtt ggcactggct gttgaagctg gcgatatcga agccaaacaa cgtcttgcgg
    10501 aagccaatct tcgtttggtt gtttccattg ccaaacgcta tgtcggtcgt ggcatgcagt
    10561 tccttgactt gattcaagaa ggaaatatgg gcttgatgaa ggcggttgac aagtttgact
    10621 attctaaagg gttcaagttt tcaacttatg caacttggtg gattcgtcag gctatcactc
    10681 gtgctattgc ggaccaagct cgtaccatcc gtatcccagt tcacatggtt gaaactatca
    10741 ataaattggt tcgtgaacag cggaatctcc ttcaagaatt ggggcaagat ccgacaccag
    10801 aacagattgc tgaacgaatg gatatgacac ctgataaggt tcgtgaaatc ttgaagattg
    10861 cccaagaacc agtatctctt gaaactccta tcggtgaaga ggacgatagc caccttggag
    10921 actttatcga agatgaagtg attgaaaatc cagtggatta tacgactcgt atcgtcttgc
    10981 gtgagcaatt ggatgaaatc ttagatactc ttacagaccg tgaagaaaat gttctgcgtc
    11041 tacgttttgg actagatgat ggaaaaatgc gcacacttga agatgtgggg aaagtcttta
    11101 acgtaactcg tgagcgtatc cgtcagattg aagcaaaggc tttgagaaaa ctacgccaac
    11161 caagtcgcag caaaccgctt cgtgatttta ttgaagacta agagtgagga aaatatggct
    11221 tatacagaag agcaaattga aaacatcaaa acacggattt taacagcctt ggaagaagtc
    11281 atcgaccctg agttgggaat cgatattgtc aatcttggtt tgatctatga gattcgtttt
    11341 gacggtgaca cagggcaaac agagattgac atgactttga caactatggg ttgtccctta
    11401 gcagaccttt tgacagacca gatttatgat gctatgatag aggttccaga agtaacggat
    11461 actgaggtta aattagtctg gtatccagcc tggacagttg aaaaaatgag tcgctatgcc
    11521 cgcattgccc taggcattaa gtaaacatat aaaagcatgt gagagactag aggaaaagcg
    11581 aggaaatttc ccctcttttc ctctagtctc tcctttcttt tgctgatttt attcaaagaa
    11641 aatgatataa tagtagttat ggagaaaaag aaattacgca tcaatatgtt gagttcaagt
    11701 gagaaagtag caggacaggg agtttcaggt gcttaccgtg aattagttcg tcttcttcac
    11761 cgtgctgcca aggaccaatt gattgttaca gaaaatcttc caatcgaggc agatgtgact
    11821 cactttcata cgattgattt tccctattat ttatcaacct tccaaaagaa acgctcaggg
    11881 agaaagattg gctatgtgca tttcttgcca gctacacttg aaggaagttt gaaaattcca
    11941 tttttcttaa agggaattgt gaaacgctat gtattttctt tttacaaccg gatggagcac
    12001 ttggttgtgg tcaatcctat gtttattgag gatttggtag cagctggtat tccacgtgaa
    12061 aaagtgacct atattcctaa ctttgtcaac aaggaaaaat ggcatcctct accacaagaa
    12121 gaggtagtca gactgcgcac agatcttggt cttagtgaca atcagtttat cgtagtaggt
    12181 gctgggcaag ttcagaaacg taaagggatt gatgacttta tccgtctggc tgaggaattg
    12241 cctcagatta cctttatctg ggctggtggc ttctcttttg gtggtatgac agatggttat
    12301 gaacactata agaaaattat ggaaaatccc cctaaaaatt tgatttttcc aggcattgta
    12361 tcgccagagc ggatgcgcga attgtatgct ctagcggatc ttttcttgtt gcctagttac
    12421 aatgagctct ttcctatgac tattttagaa gctgcgagtt gtgaggctcc tattatgttg
    12481 cgtgatttag atctctataa ggtgattttg gagggaaatt atcgggcgac agcgggtaga
    12541 gaagagatga aagaggctat tttggaatat caagcaaatc ctgctgtctt aaaagatctc
    12601 aaagaaaagg ctaagaatat ttccagagag tattctgaag agcatctgtt acaaatctgg
    12661 ttggactttt atgagaaaca agccgcttta gggagaaagt aaaaagtgag gtaatctatg
    12721 cgaattggtt tatttacaga tacctatttt cctcaggttt ctggtgttgc gaccagtatt
    12781 cgaaccttga aaacagaact tgaaaagcag ggacatgctg tttttatctt tacgacgaca
    12841 gataaggatg tcaatcgcta cgaagattgg caaattatcc gcattccaag tgttcctttc
    12901 tttgctttta aggatcgtcg ctttgcctac cgaggtttta gcaaggcact tgaaattgct
    12961 aaacagtatc agctagatat tatccatact cagacagaat tttctcttgg cctgttgggg
    13021 atttggattg cgcgtgaatt gaaaattcca gtcatccata cctatcacac ccagtatgaa
    13081 gactatgtcc attatattgc taaggggata ttgatccggc cgagtatggt caagtatctg
    13141 gttagaggtt tcctgcatga tgtggatggg gttatttgcc ctagtgagat tgtccgtgac
    13201 ttgctatctg attataaggt caaggttgaa aaacgggtca ttcctactgg gattgaatta
    13261 gccaagtttg agcgtccgga aatcaagcag gaaaatttga aagaactgcg tagtaaacta
    13321 gggattcaag atggtgaaaa gacgttgctt agtctttcga gaatctccta tgaaaaaaat
    13381 attcaagcag ttttagcagc ctttgctgat gttctgaaag aggaagacaa ggttaaactg
    13441 gtagtagctg gggatggccc ttatctgaat gacctcaaag agcaagccca gaacctagag
    13501 attcaagact cagtcatctt tacagggatg attgctccta gtgagacggc tctttactat
    13561 aaagcggcgg atttcttcat ttcggcatcg acaagcgaaa cgcaaggttt gacctacttg
    13621 gaaagcttag ccagtggaac acctgtcatt gctcacggaa atccttattt gaacaacctc
    13681 atcagtgata aaatgtttgg agccttgtac tatggagaac atgatttggc tggtgctatt
    13741 ttggaagccc tgattgcaac accagacatg aatgagcata ccttatcaga gaaattgtat
    13801 gagatttcag ctgagaactt tgggaaacga gtgcatgagt tttatctgga tgccattatt
    13861 tcaaataact tccagaaaga tttggctaaa gatgatacgg tcagtcagcg tatctttagg
    13921 acagttttgt atcttccgca acaggtggtt gctgtacctg taaaaggatc tagacgcatg
    13981 ttgaaggctt caaaaacaca gttgatcagt atgagagact attggaaaga ccatgaagaa
    14041 tagaaagagg aacagctatg aaaaaaacaa ttaatgagaa gcggtcgtga taaaaagatt
    14101 gcgggtgttt gtgctggggt ggcccattat ctggatatgg atccgactat cgttcaagtc
    14161 atttggggtg ttcttacttg ctgttacgga gctggaattg tagcttacat tattttatgg
    14221 attatcgcac cagtagcaac tgactattga aaactagctc aattcatgct aagataatag
    14281 aaaatagaat gtaacgaagg agagaaaaat ggcatttgga gataatggaa atcgtaaaaa
    14341 aactatgttt gagaaaataa ccttgtttat cgtgattatc atgctagtag caagtttatt
    14401 gggaattttt gcaactgcaa ttggtgccct cagtaatcta taaaatagat tcaagaaaat
    14461 ttagtgactg ggatttccca gccctttttt aaagtgagaa gaaataatga gtatgttttt
    14521 agatacagct aagattaagg tcaaggctgg taatggtggc gatggtatgg ttgcctttcg
    14581 tcgtgaaaaa tatgtcccta atggaggccc ttggggtggt gatggtggtc gtggaggcaa
    14641 tgtggtcttc gttgtagacg aaggactacg taccttgatg gatttccgct acaatcgtca
    14701 tttcaaggct gattctggtg aaaaagggat gaccaaaggg atgcatggtc gtggtgctga
    14761 ggaccttaga gttcgagtac cacaaggtac gactgttcgt gatgcggaga ctggcaaggt
    14821 tttaacagat ttgattgaac atgggcaaga atttatcgtt gcccacggtg gtcgtggtgg
    14881 acgtggaaat attcgtttcg cgacaccaaa aaatcctgca ccggaaatct ctgaaaatgg
    14941 agaaccaggt caggaacgtg agttacaatt ggaactaaaa atcttggcag atgtcggttt
    15001 agtaggattc ccatctgtag ggaagtcaac acttttaagt gttattacct cagctaagcc
    15061 taaaattggt gcctaccact ttaccactat tgtaccaaat ttaggtatgg ttcgcaccca
    15121 atcaggtgaa tcctttgcag tagccgactt gccaggtttg attgaagggg ctagtcaagg
    15181 tgttggtttg ggaactcagt ttctccgtca catcgagcgt acacgtgtta tccttcacat
    15241 cattgatatg tcagctagcg aaggccgtga tccatatgag gattacctag ctatcaataa
    15301 agagctggag tcttacaatc ttcgcctcat ggagcgtcca cagattattg tagctaataa
    15361 gatggacatg cctgagagtc aggaaaatct tgaagaattt aagaaaaaat tgtctgaaaa
    15421 ttatgatgaa tttgaagagt taccagctat cttcccaatt tctggattga ccaagcaagg
    15481 tctggcaaca cttttagatg ctacagctga attgttagac aagacaccag aatttttgct
    15541 ctacgacgag tccgatatgg aagaagaagc ttactatgga tttgacgaag aagaaaaagc
    15601 ctttgaaatt agtcgtgatg acgatgcgac atgggtactt tctggtgaaa aactcatgaa
    15661 actctttaat atgaccaact ttgatcgtga tgaatctgtc atgaaatttg cccgtcagct
    15721 tcgtggtatg ggggttgatg aagcccttcg tgcgcgtgga gctaaagatg gggatttggt
    15781 ccgcattggt aaatttgagt ttgaatttgt agactaggag actggtatgg gagataaacc
    15841 gatatctttc cgagatgcgg atggtaattt tgtttccgcc gcagacgttt ggaatgaaaa
    15901 gaaattggaa gaactattta atcgtctcaa tccaaatcgt gccttgagat tggcacgaac
    15961 taaaaaggaa aatccatctc agtaaagaag ctaaaaaatc ccgtgcctca tcagacacgg
    16021 gattttgtgg tacgacaggc atgtatagca aactgaatct ggaatagcac agcatatctt
    16081 ctaaaatatt gttataaatt gatttgaatt tcaaaattaa attgtttgat tcttatctca
    16141 atttgttata gtatatctga tgtcaaagtt ctcggcgagt caaatagcga ttcccaagcc
    16201 tgactatcgt gaggtagcgg attaaaatgg tctggggata gaccgtttta agtctgacgc
    16261 tggaaataag aattgtcaga agaagggata gcgaaatcgt ggctctacga acaggaacgt
    16321 gataataagg cgtatatagc ggataagagg gcctcaaact ctaaagtcca aaaaggtagt
    16381 cgtaacctat atgcgtaaat cacgagagta attgaattcg tactaagatt ttctattttc
    16441 actgtaacct tttaacgtcc ttatatcttg tatacacgag gaaagatgta cgacttatcc
    16501 cgtgaggtct atcactataa agagaaaacg acagatagaa gtgatcctga gtcacggtta
    16561 tctttaaaat agattgtctg ataggacggt atgtataaaa cgcttctgtg aactgagaga
    16621 agggggagaa gttcttgcta aaatttagtt gaacagccgt attccgatac ttagataaga
    16681 gatctagtct tagctcctac tcagttttag gggataaaaa aggggaaata gcgattcgag
    16741 aaagattata ctcttcgaaa atctcttcaa atcacgtcaa tatcgccttg ccgtatgtgt
    16801 aggatactga ctacgtcagt tccatctaca acctcaaaac agtgttttga gcaacctgcg
    16861 gctagtttcc tagtttgatc tttgattttc attgagtatt agtaattcag ttactaactc
    16921 gtcaactctg atttatccaa taaaattgaa aaggatggaa aaaaggataa atttatgata
    16981 tactttattt tgaagacctt attagaaatc ttgaaagagt attgaaaact tagaatgaga
    17041 aaaattgtta tcaatggtgg attaccactg caaggtgaaa tcactattag tggtgctaaa
    17101 aatagtgtcg ttgccttaat tccagctatt atcttggctg atgatgtggt gactttggat
    17161 tgcgttccag atatttcgga tgtagccagt cttgtcgaaa tcatggaatt gatgggagct
    17221 actgttaagc gttatgacga tgtattggag attgacccaa gaggtgttca aaatattcca
    17281 atgccttatg gtaaaattaa cagtcttcgt gcatcttact atttttatgg gagcctctta
    17341 ggccgttttg gtgaagcgac agttggtcta ccgggaggat gtgatcttgg tcctcgtccg
    17401 attgacttac accttaaggc gtttgaagct atgggtgcca ctgctagcta cgagggagat
    17461 aacatgaagt tatctgctaa agatacagga cttcatggtg caagtattta catggatacg
    17521 gttagtgtgg gagcaacgat taatacgatg attgctgcgg ttaaagcaaa tggtcgtact
    17581 attattgaaa atgcagcccg tgaacctgag attattgatg tagctactct cttgaataat
    17641 atgggtgccc atatccgtgg ggcaggaact aatatcatca ttattgatgg tgttgaaaga
    17701 ttacatggga cacgtcatca ggtgattcca gaccgtattg aagctggaac atatatatct
    17761 ttagctgctg cagttggtaa aggaattcgt ataaataatg ttctttacga acacctggaa
    17821 gggtttattg ctaagttgga agaaatggga gtgagaatga ctgtatctga ggacagcatt
    17881 tttgtcgagg aacagtctaa tttgaaagca atcaatatta agacagctcc ttacccaggc
    17941 tttgcaactg atttgcaaca accgcttacc cctcttttac taagagcgaa tggtcgtggt
    18001 acaattgtcg atacgattta cgaaaaacgt gtaaatcatg tttttgaact agcaaagatg
    18061 gatgcggata tttcgacaac aaatggtcat attttgtaca cgggtggacg tgatttacgt
    18121 ggggccagtg ttaaagcgac cgacttaaga gctggggctg cactagtcat tgctgggctt
    18181 atggctgaag gtaaaactga aattaccaat atcgagttta tcttacgtgg ttattctgat
    18241 attatcgaaa aattacgtaa tttaggagcg gatattagac ttgttgagga ttaaaccgta
    18301 gaggtgttta tgaatatttg gaccaaatta gcaatgtttt ctttttttga aacggatcgc
    18361 ttgtatttgc gtcctttctt ttttagtgat agtcaggact tccgcgagat agcttcaaat
    18421 ccagaaaatc ttcaatttat tttcccaacg caggcaagtc tggaagaaag tcaatatgca
    18481 ctggccaatt actttatgaa gtcccctttg ggagtgtggg caatttgtga ccagaaaaat
    18541 caacaaatga ttggttctat taaatttgag aagttagatg aaatcaaaaa agaagctgag
    18601 cttggctatt ttttgagaaa agatgcttgg tcgcaaggat ttatgacaga ggttgttaga
    18661 aaaatttgtc agctttcttt tgaggaattt ggcttaaaac aattatttat cattacccac
    18721 cttgaaaatg aagctagcca aagagttgct cttaagtctg gatttagttt gttccgtcag
    18781 tttaagggaa gtgatcgtta cacaagaaaa atgcgggatt atcttgaatt tcggtatgta
    18841 aaaggagagt tcaatgagta agcatcagga aattctaagc tatttggagg aattaccagt
    18901 aggtaaaagg gtcagtgttc gtagcatttc gaatcatcta ggagttagtg atggaacagc
    18961 ctatcgagct attaaagaag ctgaaaaccg tggaattgtg gagacccgtc ctagaagtgg
    19021 aacaattcgt gttaaatccc agaaagttgc tatagataga ttaacgtttg ctgaaattgc
    19081 agaagtgact tcttctgagg ttctggctgg gcaagaaggt ttagagagag aatttagtaa
    19141 gttttcaatt ggtgccatga ctgaacaaaa tatcttgtct taccttcatg atggggggct
    19201 cttgattgtc ggagaccgaa cccgtattca gttgctagcc ttggaaaatg aaaatgcagt
    19261 tctggttaca gggggatttc aggttcatga tgatgtgctt aaactggcca atcaaaaagg
    19321 gattcctgtt ctaagaagta agcatgatac ctttaccgtc gctaccatga tcaataaagc
    19381 cttgtcaaat gtccaaatca agactgatat tctgacagtt gagaaacttt atcgccctag
    19441 tcatgagtat ggttttctga gagagacaga tacagttaaa gattatttgg acttggttcg
    19501 taagaatcgt agcagccgtt tccctgttat caatcaacat caggtcgttg ttggcgttgt
    19561 aaccatgaga gacgctggtg ataaatcacc aagcacgaca attgataagg ttatgtctcg
    19621 tagtctattt ttggttggat tatcgacaaa tattgccaat gtgagtcaac ggatgatcgc
    19681 agaagacttt gaaatggtac cagttgttcg aagcaatcaa actttgcttg gcgttgtgac
    19741 gcgacgagat gtcatggaga agatgagccg ttcccaagtt tcggctctac caactttttc
    19801 tgagcagatt ggacaaaagc tctcttatca ccatgatgaa gtagtcatta cagtggaacc
    19861 ctttatgcta gaaaaaaatg gagttttggc taatggtgta ttggcagaaa ttctgaccca
    19921 catgacccaa gatttagttg ttaatagtgg tcgcaatctc attatcgagc agatgctgat
    19981 ctactttttg caggccgttc agatagatga tatattgcgc attcaggcac ggattattca
    20041 tcatacgaga cggtcagcta taattgatta cgatatttat catggtcacc agattgtttc
    20101 aaaagcaaat gtgactgtta aaattaatta gaaactagga gaaaagatga taacattaaa
    20161 atcagctcgt gaaatcgaag ctatggacaa ggctggtgat tttctagcaa gtattcatat
    20221 aggcttacgt gatttgatta agccaggcgt agatatgtgg gaagttgaag aatatgtccg
    20281 ccgtcgttgt aaagaagaaa atttccttcc acttcagatt ggggttgacg gtgccatgat
    20341 ggactatcct tatgctacct gttgctctct taacgatgaa gtggctcacg ctttccctcg
    20401 tcattatatc ttgaaagatg gtgatttgct caaagttgat atggttttgg gaggtcccat
    20461 tgctaaatct gacctaaatg tctcaaaatt aaacttcaac aatgttgaac aaatgaaaaa
    20521 atacactcag agttattctg gtggtttagc agactcatgt tgggcttatg ctgttggtac
    20581 accgtccgaa gaagtcaaaa acttgatgga tgtaaccaaa gaagctatgt acaagggtat
    20641 tgagcaagct gttgttggaa atcgtatcgg tgatatcggt gcggctattc aagaatacgc
    20701 tgaaagtcgt ggttacggtg tagtgcgtga tttggttggt catggtgttg gcccaactat
    20761 gcacgaagaa ccaatggttc ctaactatgg tattgcaggt cgtggactcc gtcttcgtga
    20821 aggaatggtc ttaaccattg aaccaatgat caatacaggc gattgggaaa ttgatacaga
    20881 tatgaaaact ggttgggcgc ataagaccat tgacggtgga ttgtcatgtc agtatgaaca
    20941 ccaatttgtc attacgaaag atggacctgt tatcttgact agccaaggtg aagaaggaac
    21001 ttattaataa aaagtgaaaa gactactgga agtttattat gaaaaaatcc agtagatctt
    21061 ttcataataa aacgcattgt atcaagtgtt aggggctgat atcatgcgtt tttctgcttt
    21121 taagattttt tccaactctg tttgtaagcg catcataaca aagggtctag gattcagggc
    21181 tctcctccta tatactatta gtaaagtaaa actaagggag gatattttag tgtcgcagtc
    21241 tattgttcct gtagagattc cacaatattg tcgttttgat tctaaaaaga gaaatggaat
    21301 tctgtttaat gttcgtattg ccaatcttaa atttaccttt tttagattag acttcctgcg
    21361 aaacaaaaca tggtatagta gttctatgaa tgatgaagca agtaaacaac taac
//
LOCUS       DAVBIC010000041        21360 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.041, whole genome shotgun sequence.
ACCESSION   DAVBIC010000041 DAVBIC010000000
VERSION     DAVBIC010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21360)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21360)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21360
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.041"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            182..658
                     /locus_tag="VQ664_001504"
     CDS             182..658
                     /locus_tag="VQ664_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2789651.1"
                     /translation="MKLSLYSEVEHYHFLSSYSLNDITYTDTPKNIIEKSKKDKYRYP
                     IVILNKDHKVIGFFCLHLNTGPKEYGYYQNDYALIRGFSIHDNFRNQGYGSNALNEIF
                     EFIDSTLKLEINHIILAVNEKNILAQKAYRNSGFSVVKKDLEGKRGKLIIMEKSRN"
     gene            complement(1332..1724)
                     /locus_tag="VQ664_001505"
     CDS             complement(1332..1724)
                     /locus_tag="VQ664_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HET2789652.1"
                     /translation="MWKKKKVKAGVLLYAVTIAAIFSLLLQFYLTRQIAHYQDYALNK
                     EKLVAFAMAKRTKDKAEQESGEQVFNLGQVSYQNKKTSLVTTVRTDKSQYEFLFPSVK
                     IKEEKTDKKEEVATDSSEKAEKKIRREA"
     gene            complement(1702..2163)
                     /locus_tag="VQ664_001506"
     CDS             complement(1702..2163)
                     /locus_tag="VQ664_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HET2789653.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQAMSQLLI
                     SEVRYQQQSEQKEWLLFVGQLEAELDRSQFEKVEGNRLYMKQDDKDIAIGKSKSDDFR
                     KTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES"
     gene            complement(2126..2386)
                     /locus_tag="VQ664_001507"
     CDS             complement(2126..2386)
                     /locus_tag="VQ664_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789654.1"
                     /translation="MILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVA
                     KMALQTGQNQVSINGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            complement(2391..2819)
                     /locus_tag="VQ664_001508"
     CDS             complement(2391..2819)
                     /locus_tag="VQ664_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HET2789655.1"
                     /translation="MEGQIVKSMIKAFTMLESLLVLGLVSILALGLSGSVQSTFAAVE
                     EQIFFMEFEELYRETQKRSVASQQKTSLNLDGQMISNGSQKLTVPKGIQAPSGQSITF
                     DRAGGNSSLAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            complement(2788..3114)
                     /locus_tag="VQ664_001509"
     CDS             complement(2788..3114)
                     /locus_tag="VQ664_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HET2789656.1"
                     /translation="MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLDKNEDATLSKLQGDGRITEEQVKAYNEYYTKNGGA
                     NRKVND"
     gene            complement(3116..4132)
                     /locus_tag="VQ664_001510"
     CDS             complement(3116..4132)
                     /locus_tag="VQ664_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HET2789657.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSSLLDKQCVTQMRTGLSQGKSFSEMMESLGCSSTIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLDFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
                     LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEIGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            complement(4080..5021)
                     /locus_tag="VQ664_001511"
     CDS             complement(4080..5021)
                     /locus_tag="VQ664_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HET2789658.1"
                     /translation="MVQEIAQEIIRSARKKGTQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKMASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAN
                     RDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            complement(5097..5462)
                     /locus_tag="VQ664_001512"
     CDS             complement(5097..5462)
                     /locus_tag="VQ664_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HET2789659.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            complement(5613..6671)
                     /locus_tag="VQ664_001513"
     CDS             complement(5613..6671)
                     /locus_tag="VQ664_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HET2789660.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVN
                     SSDPKKAIKEIYDLTDGRGVDVAIEAVGIPETFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            complement(6834..7985)
                     /gene="nagA"
                     /locus_tag="VQ664_001514"
     CDS             complement(6834..7985)
                     /gene="nagA"
                     /locus_tag="VQ664_001514"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HET2789661.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            complement(8138..9955)
                     /locus_tag="VQ664_001515"
     CDS             complement(8138..9955)
                     /locus_tag="VQ664_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HET2789662.1"
                     /translation="MRIKWFSLIRIIGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNNEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     AGVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMIFLLSATAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPILQTLRPLPYIHAILAAGTGILTFIVCMVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHHMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            complement(10056..11198)
                     /gene="tgt"
                     /locus_tag="VQ664_001516"
     CDS             complement(10056..11198)
                     /gene="tgt"
                     /locus_tag="VQ664_001516"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HET2789663.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMLLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAECGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFRKYFVEKYGYNKSGRNF"
     gene            11328..12185
                     /locus_tag="VQ664_001517"
     CDS             11328..12185
                     /locus_tag="VQ664_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HET2789664.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSGFLNP
                     LSRIHGTVLEQPFFSILGQILQTYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQHFVLDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            complement(12213..12857)
                     /gene="pcp"
                     /locus_tag="VQ664_001518"
     CDS             complement(12213..12857)
                     /gene="pcp"
                     /locus_tag="VQ664_001518"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HET2789665.1"
                     /translation="MKVLVTGFEPFGGEKGNPTLEAIKGLPAEIHGAEVRWLEVPTVF
                     HKSAQVLEEEMNRYQPDFVLCIGQAGGRTSVTPERVAINQDDARISDNEDNQPIDRPI
                     RPDGASAYFSSLPIKAMVQAIKKEGLPASVSNTAGTFVCSHLMYQALYLVEKKFPYVK
                     AGFMHIPYMMEQVVNRPTTPTMSLVDIRRGIEAAIGAMIEHGDQELKLVGGETH"
     gene            complement(12964..13332)
                     /locus_tag="VQ664_001519"
     CDS             complement(12964..13332)
                     /locus_tag="VQ664_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HET2789666.1"
                     /translation="MSIITIILTTIVALEHFYIFYLESIATRSDATSRVFNMEKEELA
                     HPSVSSLFKNQGIYKALLGVFLWYGIYFSQNLEIVTIFVLFVIGAATYGSLTADKKII
                     LKQGGSAILALISILLFKYT"
     gene            complement(13343..13768)
                     /locus_tag="VQ664_001520"
     CDS             complement(13343..13768)
                     /locus_tag="VQ664_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HET2789667.1"
                     /translation="MIEIQDLLYQLRLSEQASTQLFEKRLGISLTRYQILLFLLEHSP
                     CNQMAVQERLKIDQAALTRHFKILETEGLVERHRNPENQREVLVEAAKYAKEQLVVNP
                     PLQHIKVKEEMESILTEFERTELSRLLNKLVLGIENIEI"
     gene            complement(14193..15335)
                     /locus_tag="VQ664_001521"
     CDS             complement(14193..15335)
                     /locus_tag="VQ664_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HET2789668.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEAPKEVASSSEVTKTV
                     IASEEVAPSTGTSVPEEQTAETSSAVAEEAPQGTTPAEKQETQASPQAASAVEATTTS
                     SEAKEVASSNGATAAVSTYQPEETKIISTTYEAPAAPDYAGLAVAKSENAGLQPQTAA
                     FKEEIANLFGITSFSGYRPGDSGDHGKGLAIDFMVPERSELGDKIAEYAIQNMASRGI
                     SYIIWKQRFYAPFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG"
     gene            complement(15501..16121)
                     /locus_tag="VQ664_001522"
     CDS             complement(15501..16121)
                     /locus_tag="VQ664_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET2789669.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQNLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNTFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLNSDNTY
                     YIGDRTLDVEFAQNSGIQSINFLESTYEGNHRIQALADISRIFETK"
     gene            complement(16125..17405)
                     /locus_tag="VQ664_001523"
     CDS             complement(16125..17405)
                     /locus_tag="VQ664_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HET2789670.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTILSRLVGLVILWSQLKLPYGKLTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVATA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMSLKG"
     gene            complement(17466..18950)
                     /locus_tag="VQ664_001524"
     CDS             complement(17466..18950)
                     /locus_tag="VQ664_001524"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HET2789671.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPVTYPKVDLDF
                     DKLKDASYQEVAKLVLSAFLDDFTAEELDYCINNAYDSKFDTPAIAPLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFADVPGT
                     EIIVFYPKGGVSKVQELQMTTQNGDNTHVIAIDGNFDDAQTNVKHMFNDVALREKLTT
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIVAGEKVNFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNNAEKTAELMNALNTQGQYKLTDFDAEILDLFAAEYATEEETAAEIKRVYESDS
                     YIEDPHTAVASAVYRKYQAVTGDVTKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLEIAPIRHKTTVAAADMQAAVEAYLGL"
     gene            complement(19026..20303)
                     /locus_tag="VQ664_001525"
     CDS             complement(19026..20303)
                     /locus_tag="VQ664_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HET2789672.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     IKDLFHYLVSTLDLTVAKVDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATSEIQAFALNGDEVIIYPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKSLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            complement(20410..20493)
                     /locus_tag="VQ664_001526"
     tRNA            complement(20410..20493)
                     /locus_tag="VQ664_001526"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20457..20459),aa:Leu,seq:caa)
     gene            complement(20503..20574)
                     /locus_tag="VQ664_001527"
     tRNA            complement(20503..20574)
                     /locus_tag="VQ664_001527"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20540..20542),aa:Gln,seq:ttg)
     gene            complement(20588..20660)
                     /locus_tag="VQ664_001528"
     tRNA            complement(20588..20660)
                     /locus_tag="VQ664_001528"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20625..20627),aa:His,seq:gtg)
     gene            complement(20675..20745)
                     /locus_tag="VQ664_001529"
     tRNA            complement(20675..20745)
                     /locus_tag="VQ664_001529"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20711..20713),aa:Trp,seq:cca)
     gene            complement(20750..20830)
                     /locus_tag="VQ664_001530"
     tRNA            complement(20750..20830)
                     /locus_tag="VQ664_001530"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20794..20796),aa:Tyr,seq:gta)
     gene            complement(20843..20915)
                     /locus_tag="VQ664_001531"
     tRNA            complement(20843..20915)
                     /locus_tag="VQ664_001531"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20880..20882),aa:Phe,seq:gaa)
     gene            complement(20919..20992)
                     /locus_tag="VQ664_001532"
     tRNA            complement(20919..20992)
                     /locus_tag="VQ664_001532"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20956..20958),aa:Met,seq:cat)
     gene            complement(21006..21095)
                     /locus_tag="VQ664_001533"
     tRNA            complement(21006..21095)
                     /locus_tag="VQ664_001533"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(21057..21059),aa:Ser,seq:tga)
     gene            complement(21178..21251)
                     /locus_tag="VQ664_001534"
     tRNA            complement(21178..21251)
                     /locus_tag="VQ664_001534"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(21215..21217),aa:Ile,seq:gat)
     gene            complement(21286..21356)
                     /locus_tag="VQ664_001535"
     tRNA            complement(21286..21356)
                     /locus_tag="VQ664_001535"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(21322..21324),aa:Gly,seq:tcc)
BASE COUNT         6386 a         4879 c         3787 g         6308 t
ORIGIN      
        1 tggtattatc aatcatgaac taggattcta gttttgcagg aagtctaata atgaaaataa
       61 aggactaaag caataactct aaatacatct gatttttata ggatatttca taaaaaaaat
      121 ctacatacct agagtcctat ttagttatgt atcttacata aagagaaagg aattaattat
      181 catgaaatta tctttgtata gtgaagttga acattaccat tttttaagtt cttattcttt
      241 aaatgatatt acatatactg ataccccaaa aaatattatt gaaaagtcta aaaaagataa
      301 gtatagatac ccaatagtaa tacttaataa agaccataaa gtaattggat ttttttgcct
      361 acacctaaac actggtccta aagagtatgg ctattatcaa aatgattatg cgcttattag
      421 aggattttct attcatgata atttcagaaa tcaaggatat ggttctaatg ctctgaatga
      481 aatatttgaa ttcatagact caactttaaa attagaaatt aaccatatta tattggctgt
      541 aaatgaaaaa aatatattgg ctcaaaaagc atatagaaat tccggttttt ctgttgtgaa
      601 aaaagattta gaaggaaaaa gggggaaatt aattattatg gagaaaagca gaaactagta
      661 atgatactag tttctgcttt tctctaagtc tgctataaat ttataacatg ttgaaataag
      721 atgtgaataa attgattgca gaattcaaac caatttctaa caatgtttta gaaaactcgg
      781 cggactattc cagattcaat ccactatatt ctatcttatt tgcatatttt gagagaaata
      841 atctatatac taaactttta tgtttataat tcattccttt cgtttcactc aaggcacaag
      901 acagaatgaa aaagtggtgt gctctttatt ttgttttata ataatagtga gaaaacctat
      961 cactactaca aatcacgggg aggtgaataa gtgagtggta tagccactac ctcgcatttt
     1021 tataggtgtc attctttcca tcaagcacaa gaactgtgac taggagcacg taaacttata
     1081 attgaataag cgactcgttt gtgaaaggaa agaatagtca agggataggc agactcaaat
     1141 ttggtgaagg gaaacccctc atgttaaaag ccaaacttca attttaaaaa ttttaaaatt
     1201 tgtttcgtat tcactactcc ttgcctttat attggattga ttaagagaac ctttcgcgtt
     1261 tctagaaact acagtggact attctggatt caacgcatta tagttgaatt gactaggaat
     1321 tctctttctt ttcaggcttc tcttctgatt tttttctccg ctttttcgct tgaatcagtc
     1381 gctacctctt cctttttatc cgttttctct tctttgattt tgactgaagg aaacagaaac
     1441 tcatattgac tcttatccgt acgaacagtc gtcaccaagc ttgttttctt gttttgatag
     1501 ctcacctgac ctagattaaa aacctgttcc ccactttctt gctcggcttt atccttggtt
     1561 cgtttagcca tggcaaaagc aaccaatttt tctttattta aagcatagtc ttgatagtgg
     1621 gcgatttgtc gggtcaaata aaattgcaac aaaagactaa agatggctgc tatggtgact
     1681 gcgtagagga gaacacctgc cttaactttc ttctttttcc acacgataga tgaactccct
     1741 ttctaagcct ttttgaaact ggaaacgaaa atgaaccagt tgattgtcct ctgtaatctg
     1801 agctgatttg aggccataaa ccataggctg atacccccgt ccactagcat cggttttacg
     1861 aaaatcgtct gactttgact taccgatggc gatgtccttg tcatcttgct tcatgtatag
     1921 gcgattgcct tctacttttt cgaactgcga acggtctaat tctgcctcaa gttggcccac
     1981 aaacaagagc cactcctttt gctcgctttg ttgctggtag cgaacttctg aaatgaggag
     2041 ctgactcata gcttgaaaaa ggagtaatcc cccactgatg acaatgaggg caagcaggga
     2101 ttctaacaag gtaaaagcct tgaccttatg gctctttgat tgccaacaac tgttctgaac
     2161 catggtagac ctccaatccc ttttcactag aaaatacctg aatctcaact ccgttgatgc
     2221 ttacctgatt ttgccccgtc tgcaaggcca tcttagctac cctcaagact tcttcctttt
     2281 gcaagatttt tgcttcctct tgcctatttt tttgaatttg tcccaaaagg agggtcgcaa
     2341 tgctggcaaa gatagctaga gcgactactg cttccagtaa aatcactgcc ctaatttttt
     2401 gtttccttaa tgcgtttaat ttttccattt cctagatata attgatagcg aatcgctcct
     2461 ttactggtct gaaattcaac cttagccagg gacgaattgc ccccagctcg gtcaaatgta
     2521 atactttggc ctgatggtgc ctgaattcct ttaggaactg tcaacttttg actgccattg
     2581 ctaatcatct gcccatccaa gttcagacta gtcttttgtt gactagctac actgcgtttt
     2641 tgggtttccc gatagagttc ttcaaactcc ataaagaaaa tctgttcctc taccgctgca
     2701 aaagtggact ggacagagcc ggacaagccc aaggcaagga tactcacaag tcccaaaacc
     2761 aagagacttt ccagcatggt aaaggcctta atcattgact ttacgatttg cccctccatt
     2821 tttagtatag tattcattat aagctttaac ctgttcttcc gtgatgcgcc catctccttg
     2881 taacttgctc agagtagcat cttcattttt atccaagcta taaagttctg cctggctttc
     2941 caccacctta acaacagctg cttttccttt gtcattgact gcttcttttt gcttggtcag
     3001 attaggtaca aagagcaaga aaagcacgct gataatcagc aagaccacca acatctccac
     3061 caatgtaaaa gctttaacct tagctttttt caagaatgtc atcatttttt tcattttaaa
     3121 aatttacctc catattttga tacatgggca tgagcattgc cgcataaagt aaaacgataa
     3181 tcagtgccac aaagataaaa accagtggct gcaccaaatt catggtgcgg ttgactcggg
     3241 taaaaaaggc ttcccaagtt ttttcagcat agatttccaa ctcactaccc agcttggact
     3301 taacttcccc atactctatg atgagactca attccttcct aaagaaagga taggttccta
     3361 tcgtctgaga aaattcacgg ccatttttca gggtttgagc cagatcttga ccgatttctt
     3421 taaagagctg ggaaccttgt tcctgcatca tttgaaaaat ctgcgtcagc tccattccct
     3481 gtgaaatcat attcccccat tcacgtgcat aataggctgt caagtaggtc tgcacaaaga
     3541 ttccaataaa gggaaggcgt gctaagatag aaaagacact catcttagaa cttcttttat
     3601 aaaaagttag tgctaaaagg gcaagcacgg aaacaagccc taccatgcct agaaaaattt
     3661 gtggcagatt accgataatt cgggtggcaa tattgctact atccagttgt gggagcaggt
     3721 aattccgtag ccccagcata attaagagaa gaaaatccag caaaatcaaa ggataggtcg
     3781 ctacttcaat taactttttc ttgaccttgg ccagattgtc tagatattct tctatctttc
     3841 ccaaactcag gtgaagattg ccatgaactt cagctagaga taactgagtg acaatggtac
     3901 ttgaacatcc caaactttcc atcatttctg agaatgattt cccctgagac aagcctgtac
     3961 gcatctgggt cacacactgc ttgtccaaca aggaactcct atctaaaaag gagatagtct
     4021 ccaccagatg aaaaccgcta gaaaagagat tgttaaatag ggtgatgata tttttttgct
     4081 tagctgtagc taattttttc cgtctcagcc tgaagacttg tgatatgtcc atctttaaga
     4141 agttggtcaa tttgctcatt ccacttggct gcttggtgtt cttgataatc tctgtttgca
     4201 aagtcaacga ttcctcctcc cccgattaat ctctggtagc agactccttg cagaacaact
     4261 gccaattctt cttcactcac acccaactcc agcagacgct cataaacacc tcggatactc
     4321 ttggcgtgaa tggttgaaaa gactgtcgca cctgtcaaac tagctctgac cactgcacgc
     4381 gccgtctcgc tgtcacgaat ttctccgata atcaagagat ctggtcgatg acgcaaggaa
     4441 agtttgatta gattttcata ggttaggccg attgcttcgt tcaactgcaa ctgaagcatg
     4501 tcgtcctgct tgatttcgac aggatcttcg atggacataa cttgctgtcc tttaaagagt
     4561 gacttggaca attcatgcat caaggtcgtc ttaccactcc caaccgggcc agcaaaaaga
     4621 tagagtcccc gttgcctgta ctgcttgcct aattcttcaa tatcctgaaa ccaaaaatgc
     4681 aagtcctgct cctcatcgtg caacaaacgg ataaccaaac tctcatgccc ccgataatcg
     4741 cctacagtag ataaacgtag agacgccatc ttctggtcat aggcataatc acaggaaccc
     4801 agttgactac gtcttttttc tcccacattc atacccgcca caaacttaaa gtgactgata
     4861 acggctgcaa acttttcaaa atcatagcta ccaattttac agcgctcgtc tcctaccctc
     4921 atatgaagct cataggcgtc taacttaggg acaaaataaa tatcctgcgt cccttttttc
     4981 cgagctgaac gaatgatttc ttgtgcaatt tcttgaacca tacttacctc ctcacctata
     5041 ctattcgcaa agcgttagaa aaataaaaaa agcaactcca aaaaagttac ttttctctat
     5101 tttaatttca tacggcaaga acgattcctt tcctgactgg tttgtttttc atagcctgag
     5161 cgtagttttt cgtctgggat aacctgctca tcctgcaaaa gagccaaaga atggtattgt
     5221 tgtaaatact catcacattc atcacaccag cgttggtctt ccgggtccca aaaaatggtc
     5281 atcaagtcgc ttctactttt ataaagaggg gattcttgtt ccaatctaaa ccagcaagtt
     5341 ttgtagtatt tgagagcatc ataatactgg tcaaattttc tacttgctac aatatcttct
     5401 tcccaacctt ctaagaacca ccacggttca aaatctccgt acatttctat aacacgatac
     5461 atattcattc attcctttgt accgtatatt ataaccaatt ccgccagaca aggaaagaaa
     5521 tatgctcatt tcttaatttt ttgataaaaa atccagccat ctgatggatg actgaatttc
     5581 tatttgctta tgtacaaaaa tatttttact acttaggctt ctgagatatc gttttcgata
     5641 atgaccttaa tggcatggtg gtctgctgcc ttactgaaga cttcgtaggc tttttcaatt
     5701 tcactgagtt tgaaatagtg agttaccaat ttttccggtt caatcttatg actttcaagt
     5761 gctttcaaca attgtggagt cgtatttgta gataccaaac cagttgttac attgatgttg
     5821 cgaatccaaa gtttatctaa atcgaattca actggtttac catgcacacc acagttggca
     5881 accgttccgt ctacaccgat aatcttttga cagaaatcaa atgtttcagg aatccctaca
     5941 gcttcgatag cgacatccac accacgacca tctgtcaaat cataaatttc tttaatggct
     6001 tttttagggt ctgaagaatt aaccttatga gtcgcaccga atgatagggc agtttccaag
     6061 cggttatcgt ctaggtctac cataatcaat ttagctggtg aatagaattg ggctgttaaa
     6121 agagcagcca atccaactgg acctgaacca ataatggcta cgctgcaacc aggttctact
     6181 ttccctttta agacaccaat ttcatatcca gtaggcagaa tgtctgacag cataaccaaa
     6241 gcttcatctg acaagtcttc tggagtatgg taaagagtat tatctgcatg agggacacgt
     6301 agatattcag cctgcatacc atcaatcaag tgaccgaaaa tccagccccc ttcgtcttca
     6361 cagtgggcat aaattccttt tttacagtag tagcatttac cacaggcaca gacgcaagaa
     6421 atcaagacct tgtcaccttt tttgaagttg gaaactcctt ccccaacttc ttcaacaatc
     6481 ccaatccctt cgtggccaag aatggtacca ctttggcaag taggaacatc ccctttgata
     6541 atatggaggt ctgttccaca aatagtggtt tttacaatac gcacaatagc gtctgttggc
     6601 ttgcgaataa ctggtttgtc tacatcaaca aaagaagcaa gtcctggttt aacataagta
     6661 taggctttca taaagcactc ctccgttttt ttatttgtaa tatttatagt tcaattgtaa
     6721 gcctttttct ttgtttcttc aagctttttt tgtgattttt ttaacttttt atttaccagt
     6781 aaagtaccct gtataaaaaa gcagaagcta gtctctaact tctgccttct ctcttatgct
     6841 tgataacgtt tcacaccatc taggtaggtt gctaccaatt ccaaatcttt atctaatacg
     6901 atgaagtcag cgtcgtagcc ttcacggatt tggccacaga cgtcatcgat gtgaacggat
     6961 ttagctgggt tgaagctggc catcatgact gcttcatgcg gattcgcaat tccccattcg
     7021 accacattct tcaaaccatc tttgagtttg aggatagaac ctgccaagtt acctgtcgat
     7081 ttgaggcgtg cagttccatt tgcaacgaca actgggaatt ctcccaacat ataatctccg
     7141 tcttccaatc ccccagctgt catacagtct gtgataagag cgatgttttc tgttcctttt
     7201 tgtttgataa gaatttcgca agcctttgga tctacgtggt gaccatcaca gatcaactct
     7261 gcataggtat gtggcaattg gtacatggct ccaaccatac ccaattcacg gtgagtcaac
     7321 ccacgcattc cattgtaggc atgcacccaa acactcgctc cagcatcgac tgcttttttg
     7381 gcttcatcaa aagtcgcgtt tgaatgtcca agagcaaccg tcacaccttc gcccgtaact
     7441 gtacgaacaa agtcttccac cccatcacgt tctggtgcaa gggcaatttt attaagcaag
     7501 ccatttgccg ctttttgcca agaatgaaac tcctcaacac ccgggtctct catataagtt
     7561 ggattttgtg cccccttaaa agtttctgtg aaatatggac cttcataata aatcccacga
     7621 atcttagcac ctgttgcttc tttataatgg tttccaagat tttcagtgac tgcaagcaat
     7681 tgctcataag tggctgttaa agttgtgggt aagaaactgg taacaccggt actaagaagt
     7741 ccttcactca tagtatgcaa tgtaccttca atgttgttgt ccatcacatc tacacctgca
     7801 tatccatgaa tatgagtatc cacaagtcct ggggcaatgc tataacctgt atagtcaatc
     7861 acctcagccc cttcaggaat ctgctctaca tgtttcccaa acttgccgtc cacaagttcc
     7921 aagtaaccac ctcgacgaac tccgtgtggg tagaaaaact gatccgcttt aatatagtta
     7981 ggcataatgt taacctcctt aaaagattga ttctacaatt tattatgtca attacattat
     8041 aaacctttct tttttatttg taaatggtat agacctattt tttggagata ttttaaaaga
     8101 gctggatttc tccaactctt ctctttttta atacaagtta ttttgattta accggcttgt
     8161 cttgagctgt ctgcaaagct gtggcaatcg tatctgcata caattttgct cctgcttcga
     8221 tagtgctact ctcactcccg aaatgaacct ggtctgttcc agcccaaatt tctggatgct
     8281 ctttcgcaac ttgattccaa tctgctatcg taatgtaagg tgtcttctct gccaattctc
     8341 tcatataggc agcagccttc tcaacgatgg cataggtctc ttttgtctta tctccctcat
     8401 aaggagtcac caaaatcata tggtgtccct taggaagatt tttcacgata ctgtcccagt
     8461 catccttgta attctcagga ttatttaccc cagtcgcaat gaccaccgtc ttaggtaaaa
     8521 atttattctg gctattattt agcatgattt catttgcggt cttggttgtt acgctgacct
     8581 gcgcgttaat ctgtgctcca ggaagagctg tctgtagtgc tgtatttgcc cttaaagcca
     8641 ctgagtcacc aattaacata gtgccatcag caattcccaa actgtttgca tctgcccgtt
     8701 ctgccatcac cttggtctgg ccaatatttg ttgcagcttg cttcaagcca ttgacagtca
     8761 agtctgtctc aaacgctccc acttgtggtg ccaacaaggt caccatgcag acaatgaagg
     8821 tcaagattcc tgtacctgct gcaagaattg cgtgaatata aggcagggga cgaagagttt
     8881 gtaaaatagg tgtgttcttg cctgcaatcc aaggttccaa tacataaaat gacagactgg
     8941 caaagccata agaacaaatc agagtcagta atacagcaag aagatttgat gtcaactgtg
     9001 agaaaatgat atagaaaggc caatggaaaa gataaaccgc atagctagta tccgctaaaa
     9061 agctgataat cttcggctcc tgtatatgat gtgtcttttc atgtaagaca cgcgccgcca
     9121 gaatcatggc aagagctgca agactggcaa gcaagaagcc gataagatag gcaaaaagat
     9181 aagtgaattt gacaaagaaa gtcaaaagaa ctaggaaacc aaagcctcct ccaaaaacta
     9241 ctaaagtctt tcgtaaatcc cagattttat ccaactgctt gacgagggaa gtcgtctgac
     9301 gaacgcctac aatagttgct aacatacttc ccaaaaagaa tggatagaca tgagttaaac
     9361 tggagaaata aacagaggaa taagaggtca ctagaaaact accaataaac atggagaaga
     9421 aactgatcaa gaaggcagta gcagataaga gaaagatcat ccccttcaac tgaccatttg
     9481 atttagcttg tttggataag aaccaaactg ccaatcccca aagaatatag tagtgaacct
     9541 caactgccaa actccaatta tgaacaaaca aatgaggaat gaactgagat tcataactcc
     9601 cacctgttaa gagttcatag aagttggtca taaagcctaa gacgcccgca atctggccac
     9661 caattccagc aacatagtct tggcgaacca agaaagtaaa aggcatggtc accaagacca
     9721 tcaaaaccac aggtggcaca atccgataaa agcgtcttct aaaaaatcct atcaaatcaa
     9781 tctcattgtt cttagaaaat tcttcaatga gtagagctgt aatcaggaaa cctgaaaatg
     9841 tgaaaaagac atctaccccg aaaaatcctc caggaaagat cgtctgaaag aagtgataca
     9901 agagtaccaa aagtaaacct ataatcctaa tcaaggaaaa ccatttaatg cgcatacgag
     9961 tttattcttc ctttcattgt acactttatt ctatcaaaaa aagaagaaaa atcctaagag
    10021 aaaacttagg atttttagct tatatcaatt ccattttaga aattacgtcc tgacttatta
    10081 tagccatatt tttccacaaa atacttacgg aattccaaga gattgtcatc catgatggct
    10141 tgtcgcactt gcttcatcag gttaagcaag aagtaaagat tgtggtagct agtcaagcgg
    10201 ataccaaagg tttcatcagc cttgagcagg tgacgaaggt aagcgcgtgt atagttatta
    10261 catgtgtagc aatcacactc aggatccagt ggcgtaaagt cctcagcaaa ctgggcattt
    10321 ttcacaacca aacgtccttg actggtcata caagtcccgt tacgagcaat tcgagtcggt
    10381 aagacacagt caaacatatc caccccacga atgaccccat cgatcaagct atctggcgct
    10441 cccacaccca tcagataacg aggtttattt tcaggcagca gttgagttgt aaagtccaag
    10501 accgcattca tctcttcatg ggtttctccc actgccaaac caccgataga gtagcctgag
    10561 aaatccatgc tgacaagatc gtgagctgat tggcggcgaa ggtcttcaaa tcctgcacct
    10621 tgcacaattc caaacaaacc ttggtcatgt ggacgacggt gagccttcaa accacactca
    10681 gcccaacggc tggtacgctc gatcgatttc ttaacgtagt cataaggttg ataaaactga
    10741 ggacattcat caaaggacat catgatgtct gaacccagat tattctgaat agagatggct
    10801 ttttctgggg ataggagcat cttagaacca tttagatgat ttttaaaggt tactccttct
    10861 tctgtgatat tacggctatc tgctaaagaa taaacctgaa aaccaccact atctgtcaag
    10921 ataggctggt cccaattcat gaacttgtgg agaccaccag cgcgtgcaat gagttcatct
    10981 ccagggcgaa gccagagatg ataggtgttt gataggataa ttcccgaacc catctccttc
    11041 aattcttcag gtgactgagt tttgacagtg gcttgtgtcc caactggcat aaacataggt
    11101 gtcggaaagg taccgtgggg agtgatgatt tctcctagac gagctcctgt gtgtttttct
    11161 ttcttaatca aacgatattt gattggtgaa tctgacattt tttacctccg aagctgggaa
    11221 agacagtccc agttcataca gtgtgcccaa ggacacactg tatgatttta tcaaaaaaag
    11281 taggaactgt cacgaactat gtataagaac tatggtataa taagagaatg aactatccaa
    11341 aaattgattt aaaaacaatt cgtcaggagt caaaacattt tcaggctgac accccccgtc
    11401 tctttctcct ctatatcctt cccagtatgc tggtcatctt atctggtttt cttaatccct
    11461 tatctcggat ccacgggact gttttagaac agccattttt cagcatactt ggccaaatac
    11521 ttcaaaccta cctctttcct ctactagtct cctttatcgg gactattctt ttgaccagtt
    11581 ccgtctatgc aacactgaca ctcatgaaag attctaaaac ggagccatct gtaaaaaaca
    11641 gcctagctct ctttgatgag gagcgctttt ctcaaacctt tttgacccta cttctcaaac
    11701 gtttctatct ctttttatgg agtatcccta atttacttgg gatttacctc ctcttttata
    11761 gtagcttttt agccaaaaaa ttcgtcaccc tacatcctga gtttccaaat ctagatctct
    11821 catcagttga aaccgagcgt ttcctcatgg tctttggact ctactttctt gcaagtctca
    11881 tcttgatcat tgtaggaaat atcctctata ttccacagta ttatgcctat tcacaggtgg
    11941 aatttcttct ctgttatagt ctagacctag gacaggtccc accaagacga atcctaaaaa
    12001 ctagccgttc ctttatgaag ggctacaagt tccagcactt tgtcctagat ttacagcttc
    12061 ttccttggta cttcctcaat tggattacct ttggcattgc tagtttttca ctcctacctt
    12121 atatccaatg cactaaaatt atgttttacc gagcagtatt ggctcgaaaa cgtccaaaag
    12181 cttgaaggtt tttcccctca agcttttttc tatcaatgag tttctccgcc taccaacttg
    12241 agttcctgat ctccatgttc tatcatagcg ccgattgctg cttctatccc tcgccgaata
    12301 tccactaaac tcatagttgg agtagtcggt ctgttcacca cctgttccat catataagga
    12361 atatgcataa aacctgcctt aacatatgga aatttctttt ctaccaaata gagagcctga
    12421 tacatcaaat ggctgcagac aaaagtccct gccgtattgg aaacagaggc cggtaagccc
    12481 tcttttttta tagcttgaac catcgcttta atcggcaaac tactaaagta ggccgaagca
    12541 ccatctgggc gaatgggacg gtcaatcggt tgattatctt cgttatcaga aatgcgtgca
    12601 tcgtcttgat taatggccac tcgttcaggt gtcacactag ttcttccacc agcttgccca
    12661 atacaaagga caaagtcagg ttgataacga ttcatctctt cttccaatac ttgagcagat
    12721 ttgtgaaaaa ctgtcggcac ctctagccaa cggacctcag caccatggat ttcagctggt
    12781 aaacctttaa tggcctccaa agttggattg cccttttccc ctccaaaggg ctcaaaacct
    12841 gtcactaata ctttcatttc taactcctca aaaccaattc aatgagactt ttttcttaaa
    12901 aacaagtata acatatttcc cttattctgg attaaaaagg attagcgaga ttaaaatcga
    12961 ccttcaagtg tatttaaaga gtaaaatact aatcaaggcc aaaatagctg atccaccttg
    13021 cttcaaaata atttttttat ccgctgttaa agagccgtaa gtcgcagcac caatcacaaa
    13081 taagacaaaa atagtcacaa tttctaaatt ctgtgagaaa taaatgccat accagagaaa
    13141 gactcctagc agagccttat aaatcccttg atttttgaac aatgaactta ctgacggatg
    13201 agccaattct tccttttcca tattaaatac acgactagtc gcatctgatc gcgtagcaat
    13261 actttccaaa taaaaaatgt aaaaatgctc caaagcaacg atcgttgtta aaataattgt
    13321 aataattgac atctatttct ccttaaattt ctatattttc aatacccaaa accaatttat
    13381 ttaataaacg gctgagttct gttctctcaa actctgttaa gatactttcc atctcttcct
    13441 taaccttgat atgttgcaga gggggattca ccactaactg ctccttggca tacttcgcag
    13501 cctctaccaa cacttcccgc tgattttcag gattacgatg acgctccacc aaaccttccg
    13561 tttccaaaat cttgaaatgc cgtgtcaaag cagcctgatc aattttcaaa cgctcctgaa
    13621 ccgccatttg gttacaagga gaatgctcca gcaaaaacag taaaatctga taccgtgtca
    13681 aactaatccc aagccttttt tcaaacaatt gcgtactcgc ttgctcagac aagcggagtt
    13741 gatacagtaa atcttgaatc tctatcattt cttcctccta tccattgact tatcaatagt
    13801 tgaccaatca attataatat aaagtatagt gaaatgaaat aagagcagga caaatcgatc
    13861 aggacagtca aatcgatttc taacaatgtt ttagaagcag ttgtgtacta ttctagtttc
    13921 aatctactat aaaatagatt gcaagaatgt tgcttagatt attacaagat gataactttc
    13981 cattttccat tcaaattgat actcaatgaa aatcaaaaag caaactagga agctagtcgc
    14041 aggttgctca aagcacagct ttgaggtttc agataaaact gacgtggttt gaagagattt
    14101 tcgaagagta tgacaaagaa aaaacgaacg agaatcgctt cccatcacga aagctagatc
    14161 tcattcgtca aaatgatgtt accaagtcgg gtttatccat tcattgaaac gtgaacgtga
    14221 tcatagtgat tttctgtcac actaccacgg tctggcattg ggttccaagt gttagctggc
    14281 ccatatttgc tatcgaatgg agcatagaaa cgttgtttcc agatgatgta actaatgcca
    14341 cggctggcca tgttttgaat agcatattcc gcaatcttat cccctaattc tgaacgttct
    14401 ggtaccataa agtcgatagc caaacctttt ccgtgatctc cactgtctcc tggacgataa
    14461 ccgctaaagg atgtaatgcc aaacaagtta gcaatttctt ctttaaaggc agctgtttgt
    14521 ggttgaagac ctgcattttc agattttgct actgcaagtc cagcataatc gggcgcagct
    14581 ggagcctcgt aagttgttga aattattttc gtctcttctg gttgataagt agaaactgct
    14641 gctgtagctc catttgatga tgctacttct tttgcttctg aacttgttgt agttgcttcc
    14701 actgctgatg cagcttgagg gcttgcttgt gtttcctgct tctcagctgg agtcgttccc
    14761 tgaggagctt cttctgcaac tgcactgctt gtttcggccg tttgctcctc tgggacagaa
    14821 gtgcccgtag atggtgccac ttcttcagaa gcaatcactg tctttgtaac ttctgaactt
    14881 gatgctactt cttttggagc ttctgcaatt ggttgagaaa ggtctgcaac ctgaacagtt
    14941 tgatcatcaa cggtcacttg attagtggtc aaatctgctg tcgcagttgt cacttcttca
    15001 ctagagtctg cttgaggtgt ttggatttca acttctgtta cttcttctgc ttcattgaca
    15061 gtcgttgtca aaacagtttc tgggaaaatc aagtccatat tagtgatttt gttcagattc
    15121 gcaagcactg tgacatctac acccaaggct tctgcaatgg tgctcaaagt atcaccatac
    15181 tgtacggtat aacttgtttt gttgtccgtt ttagtcaaat cgttttggat ttgctcaaca
    15241 ctacgtgcag tccaaagaac ttcttctgct tgagttgcca atactggggc aaatgacaag
    15301 gctactgttg acgctaataa cattcttttc ttcattcttt caaattcctt tcaaatgagt
    15361 acctgtctat cataacacaa aaaatgtaga aaaaaagccc tctcgggcct atttaacaga
    15421 actgtctatt ccttgtaaca aactagatta cttgaaatag tttgttaggt ctctgtcaca
    15481 aaactgacac aatcttttta tcacttagtc tcaaaaatac gggaaatatc tgctaacgct
    15541 tgaatcctgt gattcccttc ataagtagac tctaaaaagt tgatactttg aatcccacta
    15601 ttctgggcaa attccacatc cagagtccga tcccctatat aataagtatt atcagaattc
    15661 aactgatact tatctagcag ataggtagcc gcttctggac ttggcttccg cacaaagcca
    15721 ctctgactgg tcaaaatctc tgtaaaatag gattccaccc ccaagtcctt gagaatggta
    15781 aaagtgttgt tccccttatg agtatatata aactgctgaa ttcctgattc gtctgcccaa
    15841 gctagcacct cacgcgcacc tggcatcaaa actacctgag cattcttctc agccagactc
    15901 tgggcacgca cctgatttag cacctcaaca tccagatttc tatcttctgc cacccgcaca
    15961 agcaaatttt gcaccgaata cttgaagata aactctctca ccttctcctt atcataagga
    16021 atagaaaact gagcaaaagt ctcctcaatc cctgataaaa tcgcttcgta agagtccaat
    16081 aaagtcccgt ctaaatccca aataaaagct gttttttgca tttcctatcc tttcaagctc
    16141 atatagcgct ggtaacgata gcgtagaaat aaccagcgaa aaccattatc caagagagac
    16201 cctgcccaaa taccaggcaa gccccaacca agcacaatac ccatcagata tcctgtccca
    16261 atgcggatac accacatgcc tatacttgtc gcataaaaag ggaggcgtgc atttcctaat
    16321 ccctgccaga ctgccgtata gatgactgtt cctgtcgtca taggggtacc aagtagtgaa
    16381 aacagtgtca ctagaacact agcctccacc gctagagaat cagtcgtata gagatgagtt
    16441 aatggtacac ccaagacata tatactaaag gacaggggca acatgaggaa cagagaaagc
    16501 caaaaggttt gtttactcaa actagcaact cttttccaat catcctctcc aactgctcgg
    16561 gccaacagca tgaccgttgc cgtagcgaca ccaaaggcag gcatatagtt aaactgggtc
    16621 aagacttctc cgattgcatt cccagcaact gcctccgtcc caaaagaaac gaccaaggca
    16681 atgatcacta catctccagc cctcatcata agtcgctctc cagctgctgg taaagccaag
    16741 gtcaacagtt ccttatctaa accaaaagtt agcttcccat aaggcagttt taattgtgac
    16801 cacaaaatca caagaccaac caaacgagac agaattgtcc cccaagcaac accagctatc
    16861 cccatatcca gaacaaaaat agctagactt gaaaaaagaa tattcaaggc attggataaa
    16921 aaactaacat agagaggcag acgtggatta tgcgttgcac gaatcaaggc tcccaaacta
    16981 gtcattaaac ctaagagaac aatcgatccg cctaccaaag atagatacag tccaccactc
    17041 tcagctacat ccctctccgt ccccaaaagt cctatcatct ctttcccagc gaagatggac
    17101 aaaaatccta aaaggaaact taatagtaag gtaatcttca acgcctcagt cacatgatag
    17161 gccaacttcg actggtcttt ctgccctatg ctttttgaaa taacactgga aatagcagct
    17221 cccagagcga tgaaaatcgc ctgataaatg gtgataatat taccagctac tgaaacccct
    17281 gaaatagcta tcaatcctaa atgagcaacc aaataactgt ccaccattcc cattagcatc
    17341 tgcaaaaagt tttcacccat agctggcaat gcaatattaa gaatgtcttt atttttctta
    17401 aacaatctct cctcctgatg aaaagaaact cagttggttt cccaaccgag tttgctccct
    17461 ctgtcttaaa gtcctaaata agcctcaacc gctgcttgca tgtcagcagc tgccactgtt
    17521 gtcttgtgac gaattggagc tatttcaagc ccatcaactg ctggtggcac tgcaacgcct
    17581 gagatttcat gtaattgagc caaggcttca aagtctgtca aacctgcttt tccagttaca
    17641 gcttctactg caactactgg gaacttgtat ggactagctg ttgaagcaat cactgtctta
    17701 gttacatctc cagtaaccgc ttggtatttt ctataaactg ctgaggcaac cgccgtatgt
    17761 ggatcctcaa tataagaatc tgactcataa acacgcttga tttctgccgc tgtttcttcc
    17821 tcagtcgcat attcagctgc aaagaggtcc aaaatctctg catcaaagtc tgtcaactta
    17881 tattgtcctt gcgtgttcaa ggcattcata agttcagctg tcttttcagc attatttccc
    17941 aaaagatgga aaatcaagcg ctccaagttt gaagatacca agatatccat agatgggctg
    18001 gttgttacct taaactcacg ttttttgtca tagacacgtg ttttaaagaa gtctgtcaag
    18061 acattattgt catttgaagc acagattagc ttgccaactg gtaggccgat ttgtttggca
    18121 taaaaggcag ccaagatatt tccaaagttt cctgttggta ctgtgaagtt aaccttttca
    18181 ccagctacaa tttcaccagt cttaaccaat tgagcgtaag cataaacata ataaacaatt
    18241 tgtggcacca gacgaccaat gttcatagag ttagctgatg aaaattgcaa cttgttggta
    18301 gtcaattttt cacgaagagc cacgtcgtta aacatgtgct tcacatttgt ttgcgcatcg
    18361 tcaaaattac catcaatagc aataacatga gtattgtcac cattctgagt ggtcatttgc
    18421 aactcttgta ccttgctgac accacccttt ggataaaaga cgataatctc agtaccaggc
    18481 acatccgcaa accccgccat agcagctttc cccgtgtcac cagatgtcgc tgtcaagata
    18541 acaatcttgt tctccaaacc atgtttctta gcagcagtcg tcataaagta tggcaaaata
    18601 gacaaggcca tatccttaaa ggcaatcgtt gaaccatgga aaagttccaa attgtattgc
    18661 ccatctaatt tcactaatgg tgcaatagct ggagtatcaa atttgctatc gtaggcattg
    18721 ttgatacagt agtccaactc ctcagctgta aagtcatcta aaaatgctga caaaactagc
    18781 ttagcaactt cctggtaaga agcatctttc aatttgtcaa agtccaaatc tacctttgga
    18841 taagtaaccg gtgtaaacaa accgccgtcc gtcgccaaac cttgcaaaat tgcttggctg
    18901 gcagttactg tattgttggc atcacgcgtt gattgataaa ctaatgtcat tactctctat
    18961 cctttatcta tagtctcgtc cattatatca tgatttttca gaaaattctc cctttataag
    19021 agaaattata ggctcaattc ttctctcaaa ggctgtaaat aggtcatttc ttccttattt
    19081 ctcaccacta gtccctcctc agctagtagg agtaagtctt tggaaaattc aataatcgta
    19141 gtttcttcct catctgtaag atttttctta gaaaattgtc tccttaaaga cttgtaatca
    19201 taaccaaata ctttaaagaa aggtgctgtt tctaagtaag cttctaactt gtctaaatta
    19261 accaataatc ccaagtgaaa agctgcagaa gcaaaagtcc tatcaagtgg ctgtgtacac
    19321 acactacgaa actcaactgt tcctcgagtc gttaaatctt ggtactggta actacgatga
    19381 gtttcaaaat ccttctcttg ggggtaaata ataacctcat ccccattcag agcaaatgct
    19441 tggatttcgg acgtagccaa atagtcccca gcctgaatag gataaaaata ataggtctgc
    19501 ccatcacgtt ccgcagtaaa aatcgcagaa tgatttagat agtcaaaaaa atcagcttca
    19561 tcattaagga gtctagcatt gaccccaaca ttctctggat agataccatg catagattct
    19621 tcccagaaaa tatcccttga aattttcgta tcccaatccg cacccgaaaa ttcagagttt
    19681 gcaaataaat aagccttagc cgcttcaatt tgagtaaaag cattaatcac ccgtaagtag
    19741 ttggtttttg aaatatccag ctgaacctgg ctcccacaga taaaagtacc atattcaggg
    19801 aaatgatgta aatctgattt aataatattt ctactcaaat tcaaataatc catcaacatc
    19861 tgatagcgtg gataagccac tggacaattc tcatttttat cccagttggg atggatacca
    19921 cagccaacaa tagcatgatt tgattcagct aactttctct gaattacatt catataatta
    19981 ttgaaacgat tttcgacctc ttgaatcgtt tcagccttac caaatgcaaa ctcaatcgtt
    20041 gtataggaaa cttcaaataa aatagcatcc tgacttatcg gatctactaa ctggatcaga
    20101 ttgccaaaat catctacctt tgctacggtg agatccaaag tagaaactaa ataatgaaat
    20161 agatccttta taacttcaac atctgtagca tccccttcta aacttgcaac aggatactcc
    20221 aactcaattc cgacaaacaa ttcaggattt tctttaatat ttttcaaata ccgatgtttt
    20281 aataaatcga tagaacaaga catactaccc tacactttct taatctaaat aaaatttgaa
    20341 taactataat tataccaaaa ataatataaa aaaggaacga agaataacaa cgttcctaac
    20401 actatactat accggcggcc ggggtcgaac cggcacgtcc ttgcggacac tggattttga
    20461 gtccagcgcg tctgccaatt ccgccacgcc ggcaaatagt aactggggta gctggattcg
    20521 aaccaacgca tgagggagtc aaagtccctt gccttaccgc ttggctatac cccaataata
    20581 taaaataggc gagtgatggg gatcgaaccc acgcatgcca gagccacaat ctggtgtgtt
    20641 aaccacttca ccacacccgc cataattcta ttaacacggg cagtaggaat tgaacccaca
    20701 ctgaaggttt tggagacctt agttctacct ttaaactatg cccgtaaaat ggaaggggag
    20761 ggattcgaac ccccgaaccc gaaggagcgg atttacagtc cgccgcgttt agcctcttcg
    20821 ctacccttcc aaaatatata aatggcgcga gacggaatcg aaccgccgac acatggagct
    20881 tcaatccatt gctctaccaa ctgagctacc gagccttatt gcgggagcag gatttgaacc
    20941 tacgaccttc gggttatgag cccgacgagc taccgagctg ctccatcccg cgttaataat
    21001 ataaaaggag gatgtgggat tcgaacccac gcacgctttt acacgcctga cggttttcaa
    21061 gaccgttccc ttcagccgga cttgggtaat cctccaaaat agtttatacg ggaacaagcc
    21121 cgtgtcctct tagtgaacag ataatattcc aatcccctag taatggacta aacactatgg
    21181 gcacgagtgg actcgaacca ccgacctcac gcttatcagg cgtgcgctct aaccacctga
    21241 gctacgcgcc caagtcaaaa acttggtaca aagaacaaag ttcaaagcgg gtgacgagaa
    21301 tcgaactcgc gacaacagct tggaaggctg tagttttacc actaaactac acccgctaaa
//
LOCUS       DAVBIC010000042        21102 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.042, whole genome shotgun sequence.
ACCESSION   DAVBIC010000042 DAVBIC010000000
VERSION     DAVBIC010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21102)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21102)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21102
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.042"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            <1..266
                     /locus_tag="VQ664_001536"
     CDS             <1..266
                     /locus_tag="VQ664_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HET2789673.1"
                     /translation="SIDERLRTRLRVIIWKQWKKKSRRLWGLLKLGVPKWIADKVSGW
                     GDHYQLVAQKSVLKRAISKPVLEKRGLVSCLDYYLERHALKVS"
     gene            720..1413
                     /locus_tag="VQ664_001537"
                     /pseudo
     CDS             720..1413
                     /locus_tag="VQ664_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809626.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            1469..1741
                     /locus_tag="VQ664_001538"
     CDS             1469..1741
                     /locus_tag="VQ664_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase"
                     /protein_id="HET2789674.1"
                     /translation="MFLLFSALVGMLSQLKEVPESVFLQETVEENHLVNVYSVLEVIS
                     TLAFSVFVLLMSYITESFGISISFWLSAICLMIEAILIYIRRDYFK"
     gene            2055..2186
                     /locus_tag="VQ664_001539"
     CDS             2055..2186
                     /locus_tag="VQ664_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HET2789675.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            2207..3757
                     /gene="dltA"
                     /locus_tag="VQ664_001540"
     CDS             2207..3757
                     /gene="dltA"
                     /locus_tag="VQ664_001540"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HET2789676.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKADSDS
                     LAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFVQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMIMDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGVTHFYFDG
                     EELTVKTAQKLRKRFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMNNPEKTAEAFFEFEGLPAYHTGDVGT
                     MTDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDGVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            3754..4998
                     /gene="dltB"
                     /locus_tag="VQ664_001541"
     CDS             3754..4998
                     /gene="dltB"
                     /locus_tag="VQ664_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HET2789677.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIIIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQAIPERDELMDMLDESVRYIMWGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQLLGMVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            5012..5251
                     /gene="dltC"
                     /locus_tag="VQ664_001542"
     CDS             5012..5251
                     /gene="dltC"
                     /locus_tag="VQ664_001542"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HET2789678.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            5244..6512
                     /gene="dltD"
                     /locus_tag="VQ664_001543"
     CDS             5244..6512
                     /gene="dltD"
                     /locus_tag="VQ664_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HET2789679.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKEELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            6667..7107
                     /gene="adcR"
                     /locus_tag="VQ664_001544"
     CDS             6667..7107
                     /gene="adcR"
                     /locus_tag="VQ664_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HET2789680.1"
                     /translation="MRQLAKDINAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            7107..7811
                     /locus_tag="VQ664_001545"
     CDS             7107..7811
                     /locus_tag="VQ664_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HET2789681.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYCVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNTHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVGHA"
     gene            7804..8610
                     /locus_tag="VQ664_001546"
     CDS             7804..8610
                     /locus_tag="VQ664_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HET2789682.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGRSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            8620..10125
                     /gene="adcA"
                     /locus_tag="VQ664_001547"
     CDS             8620..10125
                     /gene="adcA"
                     /locus_tag="VQ664_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HET2789683.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGEEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKVTFEKNAAAYIEKLQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISVMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNVAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(11245..12018)
                     /locus_tag="VQ664_001548"
     CDS             complement(11245..12018)
                     /locus_tag="VQ664_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET2789684.1"
                     /translation="MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLE
                     NQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCIYLDSST
                     TVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
                     NSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTG
                     FFKINPLSKYTTFISDTLPDQKLLDAVELFDGEWVSDIQ"
     gene            12194..13597
                     /locus_tag="VQ664_001549"
     CDS             12194..13597
                     /locus_tag="VQ664_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HET2789685.1"
                     /translation="MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGH
                     LSWDIDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLIDNEGKLLSQPVHYRDERT
                     KGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFN
                     YLLTGKFATEKSIASTTQLFDPRSQNWNQNILKLFELDSSLLPEIVSEGNVLGRIKKE
                     YGLGDIPVVNVCSHDTASAIVSVPKTEGSLFISSGTWSLVGVELTSPILTTESFSYGF
                     TNEVGKDGVITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTE
                     STEFATESDMHKTLTEYLAYHHETREWTDGQLFKIVYESLAETYRKAIELLEELTHKV
                     YKRIYVIGGGARASYFNQMIADRTGKEVLTGLTEATAVGNIVVQLIAMGQLKGMEEAH
                     HVIEEFLQLESYYSQKN"
     gene            13712..14350
                     /locus_tag="VQ664_001550"
     CDS             13712..14350
                     /locus_tag="VQ664_001550"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001286141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HET2789686.1"
                     /translation="MSDVKQELIKYGKKLVETDLTKGTGGNLSVFDREKQLMAITPSG
                     IDFFEIKESDIVVMDINGNVVEGERLPSSEWYMHLIQYQTRDDIDAIIHAHTTYATVL
                     ACLREPLPASHYMIAVAGKDVRVAEYATYGTKELAVNAAKAMEGRRAVLLANHGILAG
                     AQNLLNAFNIVEEVEYCAKIYCLAKNFGEPVVLPDEEMELMAEKFKTYGQRK"
     gene            14362..14802
                     /locus_tag="VQ664_001551"
     CDS             14362..14802
                     /locus_tag="VQ664_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RbsD/FucU family protein"
                     /protein_id="HET2789687.1"
                     /translation="MLKHIPKNISPDLLKTLMEMGHGDEIVLADANYPSASCANKLIR
                     CDGVNIPELLDSILYLMPLDSYVDSSIQFMNVVSGDDIPKIWGTYRQMIEGHGTDLKT
                     ITYLRREDFYERSKKAYAIVATGETSLYANIILKKGVVVERENV"
     gene            14795..15226
                     /locus_tag="VQ664_001552"
     CDS             14795..15226
                     /locus_tag="VQ664_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000483177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET2789688.1"
                     /translation="MFNRGILVASHGDFASGALMTAEMFVGETTNDRVRTLGLMPGEN
                     IVEFEHYFKNQVDELLDSNQEVIVLTDLIGGSPNNVALSRFLNLDSVDIVTGFNIPLL
                     VELISNYDSKINLEEIVHNAQNSLFNVKQQLNVEEEENLCL"
     gene            15217..15687
                     /locus_tag="VQ664_001553"
     CDS             15217..15687
                     /locus_tag="VQ664_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000020992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET2789689.1"
                     /translation="MSIEFVRIDDRLVHGQVVTTWLKKYDIEQVIIVNDRISEDKTRQ
                     SILKISAPVGLKIVFFSVKRFVEVLNSVPIKKRTMLIYTNPKDVYDSIEGNLKLEYLN
                     VGQMSKTEENEKVTGGVALGEEDKYYFKKIVDKGTRVEIQMVPNDKVTMLEKFL"
     gene            15712..16485
                     /locus_tag="VQ664_001554"
     CDS             15712..16485
                     /locus_tag="VQ664_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000899624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HET2789690.1"
                     /translation="MLFTQALLVTLVGIIATIDYNGPLFMIHRPLVTSAMVGLVLGDF
                     TQGVLIGSALELTWLGVTGIGGYTPPDTISGAIIGTAFGILSGQGETAGIAIAVPIAV
                     ATQQLDVLAKTLDVYFVKKADNDAKNGDYSKIGFYHYSSLVLITLFKIVPIFLAIMLG
                     GEYVADLFAKVPPIVMQGLNSAGALLPSIGFGMLLNMMLKKNMWVFLLIGFICSVYGG
                     MSTIGISLVGIAVAYFYDMIGSKPQETTSSSDVEEDLDL"
     gene            16482..17282
                     /locus_tag="VQ664_001555"
     CDS             16482..17282
                     /locus_tag="VQ664_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET2789691.1"
                     /translation="MMNNKVTKVELKKVFKRSFMYGSSWNYERMQNLGFLYTILPVLK
                     KLYPDKDSASPAMKRHLEFFNTHQTAAPFILGVTSAMEEQEGNEGAASITGIKVGLMG
                     PLAGLGDSLFWLTLVPICFSIGASYSKDGGALGIFIALILFNIINIPVKYFGLKYGYT
                     KGSSLIQENNTKGTLNRVTSMATALGLVLVGGLIPSMVGINFGLEFKQGELVISVQEM
                     ITKLIPGFIPMALTLLMCKLIRKGKNPVVLIFSVMAIGVILVVLGILK"
     gene            17341..19635
                     /locus_tag="VQ664_001556"
     CDS             17341..19635
                     /locus_tag="VQ664_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HET2789692.1"
                     /translation="MKLWYKKAASNWNEALPIGNGHLGGMIYGSATKECIQLNDETIW
                     YRGKSDRNNPDSLLHLKKIREYLLDGEIQKAEELIKLTMFATPRDQSHYELLGELYIE
                     HIDIQSCALSLYERELDLDTAISNVVFEPNSCNLQIKREYFTSFNKNILCCRIVSSVQ
                     NTLNLNINLGRNKRFNDEVSKLDSSTILMSASAGGRKGVQFKVVCHSKVTDGEVSVLG
                     ETIVIRNATEVFLYLKSMTDYWGNIDISSLQGEFSSIDYFTEKDEHVKKYQEQFNRVD
                     FKLDYSKDCLSIPTNLLLENTKKYSNYLTNLLFHYGRYLLISSSQPNGLPVNLQGIWC
                     DELNPIWGSKYTININTQMNYWMVGPCDLPEVEYPLFDMLERMREPGRLTAKKMYGAR
                     GFTAHHNTDGFGDTAPQSHAMGAAIWVLTIPWLCTHIWEHYLYFQDERILTEHFEMIK
                     EAFLFFEDYLFEVDGYLMTGPSVSPENKYRLKNGIEGNACLSSTIDNQILRYFCDSCI
                     GIAKQLGDNSDFISRVKELKKKLPKTKIGSNGQIQEWLEDYEEVEPGHRHISPLFGLY
                     PYNEIDIHKTPELAEAAKITINRRLSNANFLSSQEREQAINNWLVSGLHASTQTGWSA
                     AWLIHFFARLYQGEPAYNQINGLLNNATLGNLFLDHPPFQIDGNLGLVSGICELLVQS
                     HHNWLSLIPALPSAWSEGEVKGFRVRGGYKVSFAWKNGDITFLKLEGGNKDQKVRVRI
                     YGKNTDVQNIELVFNSEKIIELNF"
     gene            19645..>21102
                     /locus_tag="VQ664_001557"
     CDS             19645..>21102
                     /locus_tag="VQ664_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789693.1"
                     /translation="MNKEKIKRKLITILFVCIGMLCFGLLAGVKADNRVQMRTTINNE
                     SPLLLSPLYGNDNGNGLWWGNTLKGAWEAIPEDVKPYAAIELHPAKVCKPTSCIPRDT
                     KELREWYVKMLEEAQSLNIPVFLVIMSAGERNTVPPEWLDEQFQKYSVLKGVLNIENY
                     WIYNNQLAPHSAKYLEVCAKYGAHFIWHDHEKWFWETIMNDPTFFEASQKYHKNLVLA
                     TKNTPIRDDAGTDSIVSGFWLSGLCDNWGSSTDTWKWWEKHYTNTFETGRARDMRSYA
                     SEPESMIAMEMMNVYTGGGTVYNFECAAYTFMTNDVPTPAFTKGIIPFFRHAIQNPAP
                     SKEEVVNRTKAVFWNGEGRISSLNGFYQGLYSNDETMPLYNNGRYHILPVIHEKIDKE
                     KISSIFPNAKILTKNSEELSSKVNYLNSLYPKLYEGDGYAQRVGNSWYIYNSNANINK
                     NQQVMLPMYTNNTKSLSLDLTPHTYAVVKENPNNLH"
BASE COUNT         6542 a         3448 c         4467 g         6645 t
ORIGIN      
        1 ccagcataga tgagcgcttg cgtactcgcc tacgagtgat tatctggaag caatggaaga
       61 agaaatcgag acgattatgg ggattgctta agttaggagt tcctaaatgg atagcagata
      121 aggtatctgg ctggggcgac cattatcaat tagtagctca gaagtcggta cttaaacgtg
      181 ctatatcaaa accagtcctg gaaaaacgtg gactggtttc gtgtttggat tattaccttg
      241 aacgacatgc gttaaaagtt agttgaaccg ccgtatgccg aacggcacgt acggtggtgt
      301 gagaggggct agagattatc ctctactcga ttaactcccc tgaaatttgt tttaattatg
      361 caaatttcac gtatttttga tgctgagacg acgatcctgg gaacttttca gatatttttt
      421 tgactatcta aaatctatca ttagaaaagc ttagagcgcc aaaggatttg agcgtttttc
      481 tgatttttaa gactttttcc cagtctcttt ttcgattgaa gatgtaatta ttctactaac
      541 taacttctta gtactagcca acaacgataa tcataattcc tcctaaaatt aggaataata
      601 aaggcaatag tttttgtttt ttcatgtaaa aaacctcact tttgttttct gctattttat
      661 gctaaaatat taaaaatcaa atttaattcc aaagtttgta actaaagggg gagcgctaca
      721 tgtctaattc atttgtcaag ttgttagtct ctcaattatt tgcaaattta gcagatattt
      781 tctttagagt aacaatcatt gctaacatat acattatttc aaaatcagta attgccacat
      841 cactagttcc tatcttaata ggaatatcct cttttgttgc gagtctttta gttccgttgg
      901 ttactaaaag gttagcgcta aatagggttt tatctttatc tcaatttgga aagactatat
      961 tattggcgat actggtagga atgtttaccg taatgcaatc cgtagcgcct ttggtgacct
     1021 atctatttgt tgttgcaatt tccatactag atggttttgc agcacccgtt tcctatgcta
     1081 ttgtgccacg ctatgcgacc gatttgggta aggctaattc agccttatca atgactggtg
     1141 aagctgttca attgataggt tggggattag gtggactctt gtttgcaaca attggtctgt
     1201 tacctaccac gtttatcatt ttagtcttgt atatcatttc tagctttctg atgttatttc
     1261 ttcctaacgc tgaagtggag gtgttagagt cagaaactaa tcttgaaatt ttgctcaaag
     1321 gttggaagtt agttgctaga aatcctagat taagactttt tgtatcagca aatttattgg
     1381 aaattttttc aaatacgatt tgggtttctt ccattttgta gctatggcaa tagtgacact
     1441 gactattcta tattttccaa acgcacagat gtttttatta ttttcagctt tagttggtat
     1501 gttatcgcaa ctaaaagaag ttcctgaaag tgtatttctt caggaaacag tagaggaaaa
     1561 tcatttagtt aatgtctatt ccgttcttga agtgatttct acattagcat tttcagtatt
     1621 tgttttgcta atgagctata ttactgagag ttttggtatt agcatcagtt tttggctatc
     1681 agccatttgt ctgatgatag aagctatttt aatttatatc agacgagatt attttaaatg
     1741 agagagtggt taaaaagtct ttaaaaatca gaaaagcgca tagtatcagg tgttgaaaaa
     1801 acttgatatt gtgtgtttta ttatgggaag atttacttca ttgtctcctg aaatggagtt
     1861 ttgaagcagg atcactctat ttgaaaatat acatagaaaa actgtataat ccttaaaata
     1921 agctgaaatc tattggaaac atacggtaaa caattgaaaa ggtactatat aaagtggtac
     1981 aatggtagaa aaataagcta gtaagaatca ctcttatttt agcgaaaaat tacagaaatg
     2041 aatggttttt cttgatgaaa cagagaaaag aattgtacct ctttcttggt cggacagcct
     2101 tgtattttct tatctttcta gggctgcttt acttctttag ctatcttggt cagggtcaag
     2161 gaagctttat ctataatgaa ttttaacttg aaggagaatc cctattgtgt caaataaacc
     2221 aatagcagat atgattgaaa ccattgagca ttttgctcag acacagccta gctatcctgt
     2281 ctataatgtt ttggggcagg aacacactta tggcgattta aaggctgatt cggatagttt
     2341 ggctgcagtc attgaccaac taggcttgcc tgagaagtct cctgtggttg tttttggtgg
     2401 ccaagaatat gaaatgttgg caacctttgt agcgctgact aagtcaggtc atgcctacat
     2461 tccaattgat agccattcgg ccttggagcg agtttcagct attttagaag tagcagagcc
     2521 aagcttgatt attgccattt cagcctttcc cttggagcag gtttctacac caatgataaa
     2581 tctagctcag gttcaagaag cctttgttca agggaataac tatgaaatca cgcatccagt
     2641 caagggagat gataattact acattatctt tacttctggt acgactggta agcctaaggg
     2701 agtgcagatt tcacatgata atctcctcag ctttacaaac tggatgatta tggataagga
     2761 atttgcgaca ccgagtcgtc cgcaaatgct ggcacagcca ccttattctt ttgacttgtc
     2821 tgtcatgtat tgggcaccga ccttggcact tggtggtacg cttttcactc ttccttcagt
     2881 catcactcag gactttaagc aactctttgc ggctatcttt tcattgccaa tcgctatctg
     2941 gacatcaaca ccatcctttg cagatatggc catgttgtct gaatacttca acagtgagaa
     3001 aatgcctgga gtcacgcatt tctactttga tggtgaagaa ttgacggtca aaacagctca
     3061 aaaactgcgc aagcgtttcc caaatgcccg tatcatcaat gcttacggcc caacagaagc
     3121 gacagtagct ctgtcagcag ttgccgtgac agacgagatg ttagcgactc tcaaacgcct
     3181 accaatcggc tataccaagg ctgattctcc aacctttatc attgacgagg aaggaaataa
     3241 actgccaaat ggcgaacagg gagaaatcat tgtttctggg ccagctgttt caaaaggtta
     3301 tatgaacaat cctgaaaaaa cagcagaagc cttctttgag tttgaaggtc tgccagccta
     3361 tcacacaggc gatgtgggaa ccatgacaga tgagggcttg cttctctacg gcggacgcat
     3421 ggacttccag attaagttta acggttaccg cattgagtta gaagatgtct ctcaaaacct
     3481 caacaagtct cgctttatcg aatctgctgt cgcagtaccg cgctataaca aggaccacaa
     3541 ggtacaaaat ctattggctt atgtcatctt aaaagacggt gttcgtgagc agtttgagcg
     3601 agatatcgat attaccaagg ccatcaagga agacctgaca gacatcatga tgtcctatat
     3661 gatgccatct aaattccttt accgagacag tttgccactg actccaaatg gaaagattga
     3721 catcaaagga ttgattaacg aggtgaataa gagatgatgg agttttttca acagcttcct
     3781 catttagagc catatggcaa tcctcagtat tttgtttatg tgattgctgc aaccttgccc
     3841 atctttatag gtctcttttt caagaaacgc tttgcctggt atgaagtgtt ggtaagtctc
     3901 ttctttattg tcaccatgtt ggtgggtgga aagaccaatc aactagctgc cttgggtatt
     3961 tacctttgct gggaaatatt gctcctgctt ttctacaagc attatcgaaa aagcaaggat
     4021 ggcaagtggg tcttctactt agttagtttt ctgtccctac ttccgattat ctttgtcaag
     4081 gtgcaaccag ctatcaatgg aacgcagtct ttgcttgggt tcttgggaat ttcttatctt
     4141 acctttcgtt cggttgggat tatcatcgag ctgagagatg gagtgattaa ggattttacc
     4201 ctctgggaat tcctccgttt ccttctcttc atgccaactt tctcgagtgg tccaatcgat
     4261 cgctttaagc gatttaatga aaattatcag gctattcctg agcgagatga gttgatggat
     4321 atgctggatg aatctgtccg ctatatcatg tggggctttt tgtataagtt tatcctagct
     4381 catgttttag gagagacctt actacctcct ctgaagaatt tagccttgca gtcaggtggc
     4441 ttctttaatc tctatgcctt ggcagttatg tatacttttg gtctggagct cttctttgac
     4501 tttgcaggtt attctatgtt tgctttggcc atctcaaact tgatgggaat ccgtagccct
     4561 atcaacttta acaagccctt tttatcaagg gatttaaagg agttttggaa tcgctggcat
     4621 atgagtctgt ccttctggtt ccgtgacttt gtctttatgc gaatggtgat ggtgttaacc
     4681 agaaagaaag tctttaaaaa tcgtaatgta acctcaagca tggcctacat tgtaaatatg
     4741 ctgattatgg gattttggca tggtgtgacc tggtactata tcgcctatgg actctttcat
     4801 ggactaggct tggtcatcaa tgatgcctgg gttcgcaaga aaaaaacact caataaggaa
     4861 cggaaaaaag cagggaaggc tgccctacct gagaatcgct ggattcagtt gcttggcatg
     4921 gttgtcactt tccatgttgt catgttgtca ttcttaatct tttctggatt cttgaataat
     4981 ctatggttta aaaaataaaa ggaaataaaa tatggatatc aaatcagaag ttatcgaaat
     5041 tattgatgag ttgtttatgg aagatgtttc tgacatgatg gatgaagatc tttttgatgc
     5101 aggtgtcttg gatagtatgg gaacggttga gttgattgtg gagattgaga accgttttga
     5161 cattcgtgtc cctgtaacag agtttggtcg tgacgactgg aatacagcta ataaaatcat
     5221 agctggtatt gtggagctac aaaatgctta aacgcttatg gatgatcttc ggaccggtct
     5281 tgatcgctgg tttgttggtt tttctgctca ttttctttta tcctactgag atgcatcata
     5341 atctaggagc tgaaaagcgt tcagcagtgg ctactactat cgatagtttt aaggagcgaa
     5401 gtcaaaaagt cagagcacta tctgatccaa atgtgcgttt tgttcccttc tttggctcta
     5461 gtgaatggct tcgttttgac ggtgctcatc ctgcggtatt agctgagaaa tacaatcgtt
     5521 cctaccgtcc ttatctttta ggacaggggg gagctgcatc gcttaaccaa tattttggaa
     5581 tgcaacagat gttaccacag ctggagaata aacaagttgt gtatgttatc tcacctcagt
     5641 ggttcagtaa aaatggctat gatccagcag ccttccagca gtattttaat ggagaccagt
     5701 tgactagttt tctgaaacat caatctgggg atcaggctag tcaatatgca gcgactcgct
     5761 tactgcaaca gttcccaaac gtagctatga aggacctggt tcagaagttg gcaagtaaag
     5821 aagaattgtc gacagcagac aatgaaatga ttgaattatt ggctcgtttt aatgaacgcc
     5881 aagcttcctt ttttggtcag ttttcggtta gaggctatgt taactacgat aagcatgtag
     5941 ctaagtattt aaaaatcttg ccagaccagt tttcttatca ggcaatagaa gatgttgtca
     6001 aagcagatgc tgaaaaaaat acttccaata atgagatggg aatggaaaat tatttctata
     6061 atgagcagat caagaaggat ttgaagaaat taaaggattc tcagaaaagc tttacctatc
     6121 tcaagtcgcc agagtataat gacttgcagt tggttttaac acagttttct aaatctaagg
     6181 taaacccgat ttttatcatt ccacctgtta ataaaaaatg gatggactat gctggtctac
     6241 gagaggatat gtaccaacaa acggtgcaga agattcgcta ccagttagaa agtcaaggtt
     6301 ttaccaatat agcagatttt tctaaggacg gcggggagcc tttctttatg aaggacacca
     6361 ttcaccttgg ttggttgggt tggttggctt ttgacaaggc agttgatcct ttcctatcca
     6421 atcccacacc agctccgact taccatctga atgagcgctt tttcagcaaa gattgggcga
     6481 cttatgatgg agatgtcaaa gaatttcaat agataatata atatagaaga gttcaagaat
     6541 gaaactagtt ttcacgtttt ttcttgactc tttttttgct tgtgatataa ttaactggta
     6601 aacaaaatgt caaagaatag tatttttctc ttaaaaaaga gaagtctaaa aggaaaggag
     6661 tcagatatga gacagctagc aaaggatatc aatgcttttt tgaatgaggt gattttgcag
     6721 gcggaaaatc agcatgaaat cctaataggt cattgcacta gcgaggtggc cctgaccaat
     6781 actcaggagc atatccttat gctcttgtca gaggaatctt taacaaattc agaattggcc
     6841 cgtcgtctca atgtcagtca ggcggcagtt accaaggcca ttaagtcttt ggtcaaggaa
     6901 gggatgttgg aaacatctaa agattctaaa gatgcgcgtg tgatttttta tcagttgact
     6961 gacttggctc gtccaatcgc tgaggagcac caccatcacc atgagcatac acttttaacc
     7021 tatgaacaag tggcgactca gtttactcca aatgaacaaa aagtgattca gcggtttttg
     7081 actgctttag taggagaaat caaataatga gatatattac ggtagaggat ttgtccttct
     7141 attatgataa ggaacctgtt cttgaacata tcaattattg tgttgatagt ggggaatttg
     7201 ttaccttgac tggggaaaat ggagcggcta agacgacgct catcaaggcc agtcttggaa
     7261 ttctgcaacc acgcattgga aaggtggcta tttcaaagac aaatacgcaa ggtaagaaat
     7321 tgagaatagc ctatcttcct caacaaattg ccagttttaa tgctggtttt ccaagtacgg
     7381 tctatgaatt tgtcaagtcg ggtcgctatc cgagaaaagg ctggttccgt cgtttgaata
     7441 ctcatgatga ggagcatatc aaggctagtc tggactcagt tggcatgtgg gaacatcgag
     7501 acaaacgctt ggggtctcta tctgggggac aaaagcagcg agcggtaatt gcgcgtatgt
     7561 ttgcttctga ccctgatgtg tttatcctag acgagccgac aacggggatg gatgcaggaa
     7621 gtaaaaatga attttacgaa ctcatgcacc acagcgccca tcatcatggc aaggctgttt
     7681 tgatgattac ccatgaccct gaagaagtta aggattatgc ggatcgcaat attcatctag
     7741 tccgtaacca agactcgcca tggcgttgtt tcaacgttca tgagaatggg caggaggtgg
     7801 gccatgctta gtttattatc ttacgacttt atacaacgcg cctttttggc ggttattgct
     7861 atgagtcttt tctcaccggt attgggaacc ttcctcatct tgcgtcgtca gagtttgatg
     7921 agtgataccc ttagccacgt ctcactttca ggtgtagcct ttggtctggt tttggggatt
     7981 tctccaactg tttctactat tgccattgtc ttgattgcgg cggtctttct ggagtatctc
     8041 cgtacggttt acaagagctt tatggaaatc gggacagcta tcctcatgtc aacaggtttg
     8101 gctgtttctc tgattgtcat gagcaagggt agaagctcga gttcaatgag tttggaccaa
     8161 tatctctttg gttcgatcgt gactatcagt gaagaacagg tcatttccct ctttgtcatt
     8221 gcggcggttg ttttgatttt gacctttctc tttcttcgtc ctatgtatat cttaactttt
     8281 gacgaagata cggcctttgt ggatggcttg ccagttcgta ccatgtccat tctttttaac
     8341 atggtgacag gggtggctat tgcccttatg attcctgcag caggagctct tctggtatcg
     8401 accattatgg tcttgccagc tagtattgcc ctgcgtctgg ggaaaaactt taaatcggtt
     8461 atgctgcttg ccagtgcgat tggctttttg ggaatggtag caggacttta catttcctac
     8521 tatgcagaaa cacctgcaag tgcaagtatt accattattt ttgtaactgt ctttatacta
     8581 atcagtttag taagacgttt tatcaaatag gagacgaacg tgaaaaaaat tagcttatta
     8641 ctagccagtc tatgtgcctt gtttttagtg gcttgttcca atcaaaaaca ggcagatggt
     8701 aaactcaata tcgtgacaac cttttaccct gtctatgaat ttaccaagca agtcgcagga
     8761 gatacggcta atgtagaact cctaatcggt gctgggacag aacctcatga atacgaacca
     8821 tctgccaagg cagttgccaa aatccaagat gcagatacct tcgtttatga aaatgaaaac
     8881 atggaaacat gggtacctaa attgctagat accttggata agaaaaaagt gaaaaccatc
     8941 aaggcgacag gcgatatgtt gctcttgcca ggtggcgagg aagaagaggg agaccatgac
     9001 catggagaag aaggtcatca ccatgagttt gacccccatg tttggttatc accagttcgt
     9061 gccattaaac tagtagagca catccgcgac agcttgtcag cagattatcc tgataaaaaa
     9121 gtgacctttg agaagaatgc agctgcctat atcgaaaaat tgcaagcctt ggataaggct
     9181 tacgcagaag gcttgtctca agcaaaacaa aagagctttg tgactcaaca cgcagccttt
     9241 aactatcttg ccttggacta tggactcaaa caagtcgcaa tctcaggact ttctccagat
     9301 gcagagccat cagctgctcg cttggcagaa ttgacagagt atgtcaagaa aaataaaatc
     9361 gcctatatct attttgaaga aaatgcctca caagcccttg ctaacacact ttcaaaagaa
     9421 gcaggtgtca aaactgatgt cctcaatcct ttagaaagtc tgacagaaga ggacaccaag
     9481 gctggagaaa actacatttc cgtgatggag aaaaacctca aggctttgaa acaaacaaca
     9541 gaccaagaag gcccagcaat cgaacctgaa aaggcagagg ataccaagac agtccaaaat
     9601 ggttacttcg aggatgcagc tgtcaaggac cgcaccttga gtgactatgc aggtaactgg
     9661 caatcagttt atcctttcct tgaagacggc acgtttgacc aagtctttga ctacaaggct
     9721 aagttgactg gtaagatgac ccaggctgag tacaaggctt actatacaaa aggctatcag
     9781 acagatgtga ctaagattaa cattactgat aatactatgg aatttgttca aggtggacaa
     9841 agcaagaaat acacttacaa gtatgtcggt aagaaaattt tgacttacaa gaaaggcaat
     9901 cgtggcgtgc gtttcctctt tgaagccaca gatgctgacg ctggacaatt caagtatgtt
     9961 cagtttagtg atcacaatgt tgccccagtt aaggcagaac atttccatat cttctttgga
    10021 ggcacaagcc aagaagccct ctttgaagaa atggacaact ggccaaccta ctacccagat
    10081 aacctatctg gccaagaaat cgcccaagaa atgttggcgc attgatgaga aatcgactag
    10141 ttcataagag ctagtcggtt ttttgatact agatggctaa cttcattata gacctttcag
    10201 aactttaaac aataaataaa actcttgaaa tatctgggct tatatgctag aatgtagtta
    10261 gtgtataagg ttcattagaa caccaaagcc cctaactagt gccatagtta agggcttttt
    10321 tgacgtatct tagcgattta acgggtgttt ataggctagt cagtcggtct acttcttacc
    10381 atctagccat ttgcagacga aatacaagat aattccagct ataacatctg ctataatagt
    10441 aagagcaagc tctggtataa ggctcattag tttcacctcc tctcacgaac ccataggaac
    10501 gtaatcggta accgatgaca aaaatagtat accacactaa atttagatca tcaacctcac
    10561 ttaatgcttg aactattgta gattatatgc taaaatgtag ttaattgata aggttcatta
    10621 gaacaccaaa gcccctaact atggccgtag ttaagggctt ttttgacgta tcttagcgat
    10681 ttaacgggtg tttataggct agtcactcgg tctactcctt actatctagc catctgcaga
    10741 cgaaatacaa gataattcca gctataacat ccgctataat agtaagagcg agctctatga
    10801 taaggctcat tagtttcacc tcctctcacg aacccatagg aacgtaatcg gtaaccgatg
    10861 acaaaaatag tataccacaa tatatttaga tcatcaaggt cacttaattc ttgaaatata
    10921 gggtctaggc gacaaagtct ttaaaatcag aaaaacgcat aatatcaggt gtgcaaaaac
    10981 ttgatactat gcgttttatt gtgggaaggt ttactccatt ttctcctgaa attgagtttt
    11041 tgtccagcct ctgtttttag aattgctaag aaaataatgt catgtggtga atatttgtaa
    11101 atcagtcagc agacagaacg aatactcttc gaaaatctct tcacatcatg tcagcttcgt
    11161 cttgccgtgt ccatggggga cttgacttga tcagttttca aatctgtact ttgagcaagc
    11221 tgagactagc ttcctatttg attttcattg aatatcagaa acccattctc catcaaataa
    11281 ttcgactgcg tctaataatt tttggtctgg caaggtgtca gaaataaagg ttgtgtattt
    11341 ggagagggga ttaattttaa aaaatccagt cttgtaaaat ttagaactat caatcagtaa
    11401 gatggtttca tgggctttgt caataatatt cttttttgaa atagcttggc tgagagaagc
    11461 ttcataaaca tattggtcat caatacctct tgctgaacaa aatgctaaat cgatattaaa
    11521 atgatctaat aaagaatttt ccttatcata gttgaccacg gaacaggatt gatgtttgac
    11581 ctcgccagat gtgataaaga ttttggagct atctttaaca gtttcagata gggtttgtgc
    11641 agtatgtaaa ccatttgtaa aaataatcaa attatcaagt tcagaaagat agggacaaag
    11701 ttcgtagaca gtagtactag aatctagata gatacacata ccagaccgaa taaagtcttt
    11761 agcgagacta gcgattagtc ttttttgcct agtactttct ccttcccgta tttgatgaga
    11821 aagttcaatt gtgttcatag aggacagggt cacgtatccg tgctttcttt tgataagacc
    11881 ttgattttct aagaaaatta aatcacgacg taaggtactt gtgctggaga aagtgatttc
    11941 tgccagctct tttacggcaa ttcttttttt ctttttaata atttcaatca attcaagtac
    12001 acgttcatct tttatcataa gctcctccta atttatcatt tcaactatat tatagcacaa
    12061 attggaggaa tttgaattat ttttatgaat attgggttaa catttgaaca ttattcaagt
    12121 aagcgttcac atattgaaaa aataaaacgt ggggattata ataaagttaa tcaaggacga
    12181 agagagaaga aaaatggaag cggttttagc aatagattta ggtgcgactt ctggaagagc
    12241 aatcgttggt tacctttctg aaaataaact agtaatggaa gaaataaatc gcttttctaa
    12301 tctacctatt agagtaaaag ggcatttatc ttgggatatt gactttctac tagctaaaat
    12361 tcttgaaagt atccgcttgg ctaatactag ttacaagatt ttatctatcg gtattgacac
    12421 atggggagtt gattttggac tgattgataa tgaaggtaag ctgttatcac aacctgttca
    12481 ttatcgtgat gaaagaacaa agggagtgtt aaaggaaata tctgaaatga ctgaattaga
    12541 aaaactgtat tcagagacag gaaatcagat tatggagata aataccttgt ttcaactctt
    12601 taaggcacgt caagaatctc ctgactcttt ctataagacc aataagattc ttttaatgcc
    12661 agatttgttt aattatctct tgacaggtaa gtttgctaca gaaaaaagca ttgcttcaac
    12721 aactcaatta tttgatccta ggagtcaaaa ttggaatcag aatatcttaa aactatttga
    12781 attggattca tctttacttc ctgaaattgt ttcagaggga aatgttcttg gaaggataaa
    12841 aaaggagtat ggtttaggcg atattcctgt tgtgaatgtt tgtagtcatg atacagcaag
    12901 tgcgattgtc tcagtaccta agacagaagg tagtttattt atttcatcag gtacttggtc
    12961 tttggttgga gtggaactta cttcaccgat tcttactacc gaatccttca gttatggatt
    13021 tacaaatgaa gtcggtaaag atggagtgat tacatttctg aagaattgta cagggttgtg
    13081 gatcatagag gaactaagac gttcatttga acgaagaggg aaagcctatt cttttgatga
    13141 tattaggaca atggtggaga aagaaaaaga aaatcttcct ctgattgata ctgaatcaac
    13201 tgaatttgca acagaatctg atatgcacaa gactttgaca gaatatctag cttatcatca
    13261 tgaaactaga gagtggacag atggacaact atttaagatt gtttatgaaa gcctagctga
    13321 aacgtatagg aaagcgatag agttattaga agaactaact cataaggttt ataagaggat
    13381 atatgtgatt ggaggaggtg ctagagccag ttattttaac caaatgattg ctgatagaac
    13441 tggtaaagag gttcttacag gtttgactga ggctacagct gtggggaata ttgttgtgca
    13501 gctcatagct atgggacaat taaaagggat ggaagaggct caccatgtta ttgaggagtt
    13561 tctacaatta gagagttatt actcccaaaa gaattaaaaa gattgagagt ttgtaaattt
    13621 gcctccctcc cccttcttag cttttgtgca ggaagggggg ataattggtg aattgaaaaa
    13681 tatttagtgt tttgatatga ggaggacaag gatgtcagat gtaaaacaag aattaattaa
    13741 atatggtaag aagctagtag aaacagattt gacgaaagga acaggtggga atctcagcgt
    13801 tttcgatcgt gaaaaacaat tgatggcaat taccccgtcg ggtattgatt tctttgaaat
    13861 caaagaatcc gatattgtag tgatggatat taatggaaat gttgtagagg gagaacgctt
    13921 gccatctagc gaatggtata tgcatttgat tcaatatcaa actcgtgatg atatcgatgc
    13981 aattatccat gctcatacaa cttatgcaac agtattagct tgtctcagag aaccacttcc
    14041 agcgagtcat tatatgattg cagtggcagg gaaagatgtt cgggtagctg agtatgcaac
    14101 atatggcacg aaagaattgg ctgtgaatgc agctaaagca atggaaggtc gtagagcagt
    14161 tttactagcg aatcatggaa ttttagcagg tgcacaaaat ttattgaatg catttaatat
    14221 tgttgaagaa gttgaatatt gtgcaaaaat ttattgttta gctaagaatt ttggagagcc
    14281 agtagttctt cctgatgagg agatggaatt gatggcagaa aaatttaaaa catacggtca
    14341 gagaaaatag ggaggatatt aatgttaaaa catataccga aaaatatttc tccagattta
    14401 ttgaagactt taatggaaat gggacatgga gatgaaatag tattagctga cgcgaattat
    14461 ccttctgcct catgtgcaaa taagctaatt cgttgtgatg gcgtaaatat tccagaatta
    14521 ttagattcca ttctgtattt aatgccatta gatagttacg tcgatagttc aattcagttt
    14581 atgaacgttg tttcgggtga tgatattcct aagatatggg gtacctatag acagatgatt
    14641 gaaggtcatg gtacagatct taaaacgatt acttatctta gaagagaaga cttttatgaa
    14701 cgtagtaaga aagcttatgc tattgttgct acaggagaaa cttcacttta tgctaatatt
    14761 atccttaaga aaggagtagt tgttgaaaga gaaaatgttt aatagaggaa ttttagttgc
    14821 cagtcatggt gattttgcta gcggagctct catgaccgca gaaatgtttg ttggtgagac
    14881 aacaaatgat agagttagga cattaggttt gatgcctgga gagaatattg tagagtttga
    14941 gcattatttt aaaaatcaag tggatgaact gttagactca aatcaagagg ttatcgtttt
    15001 gactgacttg attggaggaa gtcctaataa tgtggctttg tcacggtttt taaatttgga
    15061 ttcagttgat attgtaacag ggtttaatat tcctctccta gtggaattaa tatcaaatta
    15121 tgattcaaaa atcaatttag aagaaattgt tcacaatgct caaaatagtt tgtttaatgt
    15181 taaacaacaa cttaacgtag aggaggaaga aaatttatgt ctatagagtt tgttcgtatt
    15241 gatgaccgtc tggtacatgg tcaagttgtc actacgtggc taaaaaagta tgatattgag
    15301 caagttatca ttgttaatga tcgcatctca gaagataaaa cacgacaatc tattttaaag
    15361 atttctgcac cagtaggttt aaaaattgtt ttctttagtg taaaacggtt tgtggaagtt
    15421 ttaaactctg tgccaataaa aaagagaaca atgctgatat atacaaatcc aaaagatgtg
    15481 tatgattcta ttgaaggaaa tttaaaattg gagtacctca atgtaggaca gatgagtaaa
    15541 acggaggaaa atgaaaaggt aacgggaggt gtagctctag gtgaagaaga caaatattat
    15601 tttaagaaaa tagttgataa gggaacgaga gttgaaattc aaatggttcc taatgataaa
    15661 gttacaatgt tggaaaaatt tttataaaaa taatttaagg aggtacagta tatgctattc
    15721 acacaagcat tactggtgac attagttggg attattgcca ctattgacta taatggaccg
    15781 ttatttatga ttcaccgtcc gttagttaca agtgcaatgg ttggcttagt cttaggagat
    15841 ttcacccaag gtgttcttat tggttcagct cttgaattaa cttggctcgg tgtaacaggt
    15901 attggaggtt acactccacc agatactatt tcaggtgcga ttattggtac tgcatttggt
    15961 attttatctg gtcaaggaga aactgctggt atcgctatag cagttccaat tgcagttgct
    16021 acccaacagt tggatgttct tgcaaaaact ttagatgttt attttgtgaa aaaagctgat
    16081 aatgatgcta aaaacggaga ttattcaaag atcggttttt atcattattc aagtttggtt
    16141 ttaatcacgt tatttaaaat tgtaccaatt ttcctagcta ttatgcttgg aggggaatat
    16201 gtggcagact tgtttgctaa ggttccacca atcgttatgc agggacttaa ctctgcaggt
    16261 gctttactac cttcaattgg ttttggtatg cttttaaata tgatgctcaa gaaaaatatg
    16321 tgggtattct tgttgattgg attcatttgt tctgtgtatg gaggaatgtc aaccattggg
    16381 atctcactag ttggtattgc ggtagcatac ttctacgata tgattggaag taaaccacaa
    16441 gaaacaactt caagtagtga tgttgaggag gatcttgatc tatgatgaat aataaagtaa
    16501 ctaaagttga acttaaaaaa gttttcaaac gaagttttat gtatggttct tcatggaact
    16561 atgagagaat gcagaaccta ggttttctat atacaattct tccagtattg aaaaaactat
    16621 acccagacaa agattcagct tctcctgcaa tgaaacgtca ccttgagttt ttcaatactc
    16681 atcaaacagc ggcaccattt attcttggag ttacttccgc tatggaagaa caagaaggaa
    16741 atgaaggtgc agcttcaatt actggtatta aagttggctt gatggggcca ctggctggtc
    16801 taggagatag tttgttctgg ctgacactag ttcctatctg ttttagtatt ggtgcgtctt
    16861 attctaaaga cggcggtgct ttaggtatct ttatcgcctt aatattgttt aatattatta
    16921 atattcctgt taaatatttc ggtttgaaat atgggtatac taagggttct agtcttatcc
    16981 aagaaaataa tacaaaagga acattgaatc gcgttacgag tatggcgaca gcattagggc
    17041 tagtactagt gggtggtttg attccatcaa tggttggtat taattttgga ttagaattta
    17101 agcaggggga acttgttatt tctgttcaag aaatgattac aaaattaatt ccaggattta
    17161 tccctatggc tttgacttta ttaatgtgta aattaattag aaaaggaaag aatccggttg
    17221 tactaatctt tagtgttatg gctattggag ttatcctagt tgttttagga attttgaagt
    17281 agtagaaagt gtggaggtgg tatttgggat atcacctcca ttttggaaga gaggtaaaga
    17341 gtgaaattat ggtataagaa agctgcctca aattggaatg aagccttgcc gattgggaac
    17401 ggtcatttag gtggtatgat ttatggttca gctacaaaag aatgtattca actaaacgat
    17461 gagactattt ggtatagagg aaagtcagat agaaataatc cagactcact attgcatctt
    17521 aaaaaaattc gggaatatct tttagatgga gaaattcaga aagccgaaga attgataaag
    17581 ttaacaatgt ttgctacccc aagagatcaa agccactatg aattacttgg ggaactttac
    17641 attgagcata tagatattca gtcttgtgct ctttcattgt atgaaagaga gctagattta
    17701 gatacagcta tttctaatgt tgtgtttgag cctaatagtt gtaatttaca aataaaaaga
    17761 gaatatttta cgagttttaa taagaatatt ttatgttgcc gtatagtgtc atcagttcaa
    17821 aacacattaa atttaaacat taatttgggt agaaataaac ggtttaatga cgaagtatct
    17881 aaactggatt caagtacaat tttaatgtcg gcctctgctg gaggtagaaa aggtgttcag
    17941 tttaaagtag tatgtcattc taaagttacg gatggtgaag taagtgtatt gggagagaca
    18001 atagttattc ggaatgctac agaggtattt ctttatctca aatcaatgac ggattattgg
    18061 ggaaatatag atatttcttc tcttcaggga gaatttagta gtattgatta ctttacagaa
    18121 aaagatgaac atgtaaaaaa atatcaggag caatttaata gagttgattt taaactagac
    18181 tatagtaaag attgtcttag cattccaacg aatctacttc ttgaaaacac taaaaagtat
    18241 agtaactact tgactaactt gttatttcat tatggaagat atctgttaat atcgtctagt
    18301 caaccgaatg gtttacctgt caatcttcaa ggaatatggt gtgatgaatt aaatccaatt
    18361 tggggttcta aatatacgat taatattaat actcaaatga attattggat ggtaggtcca
    18421 tgtgatttac cagaagtaga atatccatta tttgatatgc tcgaaagaat gagagaaccg
    18481 ggaagactaa ccgctaagaa aatgtatgga gctagaggtt ttacagcaca tcataatacg
    18541 gatggttttg gcgatacggc tccccaatct catgccatgg gggctgcaat ttgggtatta
    18601 actattccat ggttatgtac tcatatttgg gaacactatt tatatttcca agatgagcgt
    18661 attcttacgg aacattttga aatgataaaa gaagcatttc ttttctttga agattattta
    18721 tttgaggtgg atggctactt gatgacaggt ccaagtgtct caccggaaaa taaatatcgc
    18781 ttaaaaaatg gtattgaagg aaatgcttgt ctatcatcta caattgataa tcaaattcta
    18841 agatattttt gtgattcatg cattggcatt gcaaaacaat taggagacaa ttcggatttt
    18901 attagtcgtg tgaaggagtt aaaaaagaaa ctacctaaaa caaaaatagg tagtaatggg
    18961 caaatccaag aatggttaga agattatgaa gaagtagagc ctgggcatag acacatttca
    19021 cctctatttg ggctttatcc ttataatgag attgatattc ataaaactcc ggaattagca
    19081 gaagcagcta aaatcactat caataggaga ttatcaaacg ctaacttttt atcttcacag
    19141 gagagggagc aagcgattaa taattggtta gtaagtggtt tgcatgctag tacacaaaca
    19201 ggttggagtg ctgcatggct gattcatttt tttgcgagac tatatcaagg tgaacctgct
    19261 tataaccaga ttaatggttt gttaaataat gcgactcttg gcaatttatt tcttgaccat
    19321 ccaccatttc aaattgatgg taatttaggt ttggtgagtg gaatttgtga attattagta
    19381 cagagccatc ataattggtt atcactaatt ccagctttac cttctgcttg gtcagaagga
    19441 gaagtgaaag gtttcagagt aagaggagga tataaggtat cgtttgcttg gaaaaatggg
    19501 gatataacat tcctaaaatt ggaaggagga aacaaagatc aaaaagtaag agtaagaata
    19561 tatggcaaaa atactgatgt acaaaatatt gaattggtat ttaattcaga aaaaattatt
    19621 gagttaaatt tttaggtata agtcatgaat aaagaaaaaa taaaaagaaa attaatcaca
    19681 atactgtttg tatgtattgg gatgttatgt tttggattgt tagcaggagt taaggctgat
    19741 aatcgtgttc aaatgagaac gacgattaat aatgaatcgc cattgttgct ttctccgttg
    19801 tatggcaatg ataatggtaa cggattatgg tgggggaaca cattgaaggg agcatgggaa
    19861 gctattcctg aagatgtaaa accatatgca gcgattgaac ttcatcctgc aaaagtctgt
    19921 aaaccaacaa gttgtattcc acgagatacg aaagaattga gagaatggta tgtcaagatg
    19981 ttggaggaag ctcaaagtct aaacattcca gttttcttgg ttattatgtc ggctggagag
    20041 cgtaatacag ttcctccaga gtggttagat gaacaattcc aaaagtatag tgtgttaaaa
    20101 ggtgttttaa atattgagaa ttattggatt tacaataacc agttagctcc gcatagtgct
    20161 aaatatttgg aagtttgtgc caaatatgga gcgcatttta tctggcatga tcatgaaaaa
    20221 tggttctggg aaactattat gaatgatccg acattctttg aagcgagtca aaaatatcat
    20281 aaaaatttgg tgttggcaac taaaaatacg ccaataagag atgatgcggg tacagattct
    20341 atcgttagtg gattttggtt gagtggctta tgtgataact ggggctcatc aacagataca
    20401 tggaaatggt gggaaaaaca ttatacaaac acatttgaaa ctggaagagc tagggatatg
    20461 agatcctatg catcggaacc agaatcaatg attgctatgg aaatgatgaa tgtatatact
    20521 gggggaggca cagtttataa ttttgaatgt gccgcgtata catttatgac aaatgatgta
    20581 ccaactccag catttactaa aggtattatt cctttcttta gacatgctat acaaaatcca
    20641 gctccaagta aggaagaagt tgtaaataga acaaaagctg tattttggaa tggagaaggt
    20701 aggattagtt cattaaacgg attttatcaa ggactttatt cgaatgatga aacaatgcct
    20761 ttatataata atgggagata tcatattctt cctgtaatac atgagaaaat tgataaggaa
    20821 aagatttcat ctatattccc taatgcaaaa attttgacta aaaatagtga ggaattgtct
    20881 agtaaagtca actatttaaa ctcgctttat ccaaaacttt atgaaggaga tgggtatgct
    20941 cagcgtgtag gtaattcctg gtatatttat aatagtaatg ctaatatcaa taaaaatcag
    21001 caagtaatgt tgcctatgta tactaataat acaaagtcgt tatcgttaga tttgacgcca
    21061 catacttacg ctgttgttaa agaaaatcca aataatttac at
//
LOCUS       DAVBIC010000043        20217 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.043, whole genome shotgun sequence.
ACCESSION   DAVBIC010000043 DAVBIC010000000
VERSION     DAVBIC010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20217)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20217)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20217
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.043"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            complement(20..667)
                     /locus_tag="VQ664_001558"
     CDS             complement(20..667)
                     /locus_tag="VQ664_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HET2789694.1"
                     /translation="MDFEYFYNREAERFNFLKVPEILVDREEFRGLSAEAIILYSILL
                     KQTGMSFKNNWIDKEGRVFIYFTVEEIMKRRNISKPTAIKTLDELDVKKGIGLIERVR
                     LGLGKPNIIYVKDFMSIFQVKENDLQKSKNLTSEVKDFNLRSKENELQEVKNLDSNYI
                     ENNKSKYSKREYSFGENGLGTFQNVFLAAEDISDLQIIMNSQLENYIRLPAKLES"
     gene            complement(776..1294)
                     /locus_tag="VQ664_001559"
     CDS             complement(776..1294)
                     /locus_tag="VQ664_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HET2789695.1"
                     /translation="MRTYENKEELKAEIEKTFEKYILEFDNIPENLKDKRADEVDRTP
                     AENLAYQVGWTNLVLKWEEDERKGLQVKTPSDKFKWNQLGELYQWFTDTYAHLSLQEL
                     KAKLNENINSISAMIDSLSEEELFEPHMRKWADEATKTATWEVYKFIHVNTVAPFGTF
                     RTKIRKWKKIVL"
     gene            complement(1521..2390)
                     /gene="rsmI"
                     /locus_tag="VQ664_001560"
     CDS             complement(1521..2390)
                     /gene="rsmI"
                     /locus_tag="VQ664_001560"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HET2789696.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGTSAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFGS
                     KKDYPETQIFYESPHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     AETPLKGECLLIVEGASQDVEEKDEEDLFLEIQARIQQGMKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEEKQ"
     gene            complement(2393..2710)
                     /gene="yabA"
                     /locus_tag="VQ664_001561"
     CDS             complement(2393..2710)
                     /gene="yabA"
                     /locus_tag="VQ664_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HET2789697.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            complement(2750..3640)
                     /locus_tag="VQ664_001562"
     CDS             complement(2750..3640)
                     /locus_tag="VQ664_001562"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HET2789698.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFGSLEMAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQEEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLANQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            complement(3637..4275)
                     /locus_tag="VQ664_001563"
     CDS             complement(3637..4275)
                     /locus_tag="VQ664_001563"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HET2789699.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILEEKGVKVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLDLHKKVRQGYLSLLDKEGNRIVKIDASLPLEQVVETTKAVLFDGMGLAK"
     gene            complement(4495..5292)
                     /gene="proC"
                     /locus_tag="VQ664_001564"
     CDS             complement(4495..5292)
                     /gene="proC"
                     /locus_tag="VQ664_001564"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HET2789700.1"
                     /translation="MKIGFIGLGNMGASLTKSVLQARPSDEILLANRSQVKVDAFIAN
                     FGGQTSNNEEIFEEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLTLEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSEIFCQLLAKAGLLVELGES
                     LINAATGLAGCGPAFVYLFIEALADAGVQTGLPRETALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGTVMEAVHQAYKRTQELGK"
     gene            complement(5296..6558)
                     /locus_tag="VQ664_001565"
     CDS             complement(5296..6558)
                     /locus_tag="VQ664_001565"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HET2789701.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHENKAVSFLPRLEQ
                     VLVADRKEAGLEPIQFRLDSKASQFVSGQAAQAQDFDTEFLDYILAVKVVSSLEEAVA
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVTGDGQIRE"
     gene            complement(6568..7698)
                     /locus_tag="VQ664_001566"
     CDS             complement(6568..7698)
                     /locus_tag="VQ664_001566"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004240022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HET2789702.1"
                     /translation="MNNRSETMKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAML
                     HEAGHELILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQI
                     VSAQILLTQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDELKVGDNDTLSA
                     QVAAMVQADLLVFLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTG
                     GMLTKIKAATIATESGVPVYICSSLKSDSMVEAAEETEDGSYFVAQEKGLRTQKQWLA
                     FYAQSQGSIWVDKGAAEALSQHGKSLLLSGIVEAEGVFSYGDIVTVFDKESGKSLGKG
                     RVQFGASALEDMLRFQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            complement(7781..9661)
                     /gene="cbpE"
                     /locus_tag="VQ664_001567"
                     /gene_synonym="pce"
     CDS             complement(7781..9661)
                     /gene="cbpE"
                     /locus_tag="VQ664_001567"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HET2789703.1"
                     /translation="MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWREGIETSYKHVLTDRVFRRLKELGVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDSRITNSERLWDNLYGYDKVLQT
                     AAEKGVSVIQNITQGDAHFQFGDMDIQLYNYENETDSSGELKKIWDDNSNSLISVVKV
                     NGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQ
                     TSDSLPWKNGVDSEYVNWLKERGIERINAASKDYDATVFDIRKDGFVNISTSYKPIPS
                     FQAGWHKSAYGNWWYQAPDSTGEYAVGWNEIEGEWYYFNQTGILLQNQWKKWNNHWFY
                     LTDSGASAKNWKKIDGIWYYFNKENQMEIGWVQDKEQWYYLDVDGSMKTGWLQYKGQW
                     YYFAPSGEMKTGWVKDKEAWYYMDSTGIMKTGEIEVAGHHYYLEESGAMKQGWLKKAN
                     DWYFYKTGGSRAIGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVPIEKS
                     ATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNSSTSQDLTSSTSQSSETSVNKSE
                     SE"
     gene            complement(9664..10551)
                     /locus_tag="VQ664_001568"
     CDS             complement(9664..10551)
                     /locus_tag="VQ664_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HET2789704.1"
                     /translation="MEIKIETGGLRLDKALSDLSELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLPLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLVLAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHPVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            complement(10541..11002)
                     /locus_tag="VQ664_001569"
     CDS             complement(10541..11002)
                     /locus_tag="VQ664_001569"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HET2789705.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMFLGLTLIIAGGLG
                     NFIDRVSQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN"
     gene            complement(10999..11907)
                     /locus_tag="VQ664_001570"
     CDS             complement(10999..11907)
                     /locus_tag="VQ664_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HET2789706.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKAQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLCEGHPLAQKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            11900..12097
                     /locus_tag="VQ664_001571"
     CDS             11900..12097
                     /locus_tag="VQ664_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2789707.1"
                     /translation="MFIFYPQLLYLFIIPYFRSFPKRKKEHPILLNYLHYLPFSRQSY
                     FQNQFKKISGYTPLQYRKEKR"
     gene            complement(12149..12820)
                     /locus_tag="VQ664_001572"
     CDS             complement(12149..12820)
                     /locus_tag="VQ664_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2789708.1"
                     /translation="MKKRAIQILLALSLIFYKSTWFWRVFNHLAKPYLPASREFFQIL
                     LLMESGVLFLAVIYLLVFAGKKIFHFKWQLRYFIYLLLGYIISYMSDFLFSYFISLSS
                     NQISLNETVEMMGRQEFPYFLLIVCFIAPIAEELIYRGVLMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(12874..13095)
                     /locus_tag="VQ664_001573"
     CDS             complement(12874..13095)
                     /locus_tag="VQ664_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0924 family bacteriocin-like peptide"
                     /protein_id="HET2789709.1"
                     /translation="MILMTKNINLTNEELELIQGGADSYGKNPNGRYDWEIEPVLTLP
                     VHGFCPRGTYDLGYIGGGNHLCKGSAARF"
     gene            13367..14176
                     /locus_tag="VQ664_001574"
     CDS             13367..14176
                     /locus_tag="VQ664_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET2789710.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHITAIHKAIEKGVKLVLCTGR
                     PLFGVLPYYKKLGLDLQNEYVIVNNGCSTHQTSDWGLVDWQELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKFRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
     gene            complement(14357..15232)
                     /gene="aguB"
                     /locus_tag="VQ664_001575"
     CDS             complement(14357..15232)
                     /gene="aguB"
                     /locus_tag="VQ664_001575"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HET2789711.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKLLAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYNLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(15242..16327)
                     /gene="aguA"
                     /locus_tag="VQ664_001576"
     CDS             complement(15242..16327)
                     /gene="aguA"
                     /locus_tag="VQ664_001576"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HET2789712.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKAAKRAF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALERPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVV
                     AFVGPAEVVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEERYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            complement(16324..17451)
                     /gene="nspC"
                     /locus_tag="VQ664_001577"
     CDS             complement(16324..17451)
                     /gene="nspC"
                     /locus_tag="VQ664_001577"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HET2789713.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEAGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDEDMEELLGITDHIVF
                     NSERQLRKHGARCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGADDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPPLRNGFESQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            complement(17451..18710)
                     /locus_tag="VQ664_001578"
     CDS             complement(17451..18710)
                     /locus_tag="VQ664_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HET2789714.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVIALIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVEKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMLD"
     gene            complement(18707..19567)
                     /gene="speE"
                     /locus_tag="VQ664_001579"
     CDS             complement(18707..19567)
                     /gene="speE"
                     /locus_tag="VQ664_001579"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HET2789715.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEYDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQAFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTEYYTANLHVGAFMLPKYVE
                     DILEEEEGKK"
     gene            19823..20217
                     /locus_tag="VQ664_001580"
                     /pseudo
     CDS             19823..20217
                     /locus_tag="VQ664_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770457.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
BASE COUNT         5878 a         4644 c         3591 g         6104 t
ORIGIN      
        1 tggtattatc aatcatgaac taggattcta gttttgcagg aagtctaatg taattctcaa
       61 gctgtgagtt cattatgatt tgtaaatccg atatatcttc agcagctaaa aacacatttt
      121 gaaatgttcc aagtccgttt tcaccaaaac tatattctct cttactatac ttactcttat
      181 tattctctat atagttagag tcaaggttct taacctcttg aagttcattt tctttacttc
      241 tgaggttaaa atcttttact tctgaagtta agttttttga cttctgtaag tcattttctt
      301 ttacctgaaa tatactcata aagtctttaa cataaatgat gttcggctta ccaagtccaa
      361 gccttactct ttcgatcagt cctattcctt tttttacatc aagctcatct aatgttttta
      421 tggcagttgg ctttgagata tttcttcttt tcataatttc ttcgacagta aaatagataa
      481 atactctgcc ttccttgtct atccagttat tcttaaatga cattcctgtc tgtttaagaa
      541 gtatggaata aaggataatt gcttctgctg ataagccccg aaattcttct ctatcaacta
      601 atatctccgg tacttttaag aagttaaatc tttccgcttc tctgttataa aaatattcaa
      661 agtccatgca agatcacctc ccttcttaaa aatttgcaaa gaaaaagacg atagtttttc
      721 ttctatcgcc tttggtaacc atttttatga aattttttaa agttaaaaat ataatttata
      781 atactatctt cttccatttt ctgattttag ttctgaaagt tccaaaaggt gcaaccgtat
      841 ttacatgaat aaacttatac acttcccaag tcgctgtttt agtcgcttca tcagcccact
      901 ttctcatatg cggttcaaat aattcttcct cactcaacga atcaatcatt gcagagatag
      961 aattaatatt ttcatttaat tttgctttca actcttgcag agataaatga gcgtaggtat
     1021 ctgtgaacca ctgatataat tcaccaagtt gattccattt aaatttatcc gatggtgttt
     1081 ttacttgaag cccctttctt tcatcttctt cccatttaag aaccaagttg gtccaaccaa
     1141 cctgataagc aaggttttct gctggagttc tgtcaacttc atcagctctc ttatctttta
     1201 aattttctgg aatattatca aattctaaaa tatatttctc aaatgttttc tctatctcag
     1261 cttttagttc ttctttattt tcgtatgttc gcaaaaaatc accttctttc tgatttatca
     1321 atcctttgat ttaaaatgac cttatttttc tatttatacc ttctaagaac gctataactg
     1381 ctgctccaaa catcggtatt ccgtatgggc ttaataaaaa acttaatacc aaagcttcta
     1441 taccaagtga tacatcttta tattatcatc actaattaag ttaaacagaa acagacagaa
     1501 ttattacatc ctgtctccct ttattgtttt tcttcccaat cgtggtaggc agcgtagagt
     1561 tgactcttat tccactggta aatcttagct acttccttaa tagcttgatt tttcttcatg
     1621 ccttgctgga tacgggcttg gatttctaag aacaagtcct cctcgtcttt ttcctccaca
     1681 tcctgactgg caccttcaac aataagaagg cattcgccct tgagtggcgt ttcagcgatg
     1741 ctttccagta attcagaaat tgtacctcgt tggtattctt catagatttt ggtcaattcc
     1801 ctgaccaaaa caaccgagcg gtcaccgtag acttctaaca tattttccaa cgtgtctgct
     1861 acacgatgag gtgattcata aaaaatctgt gtttcaggat aatctttttt agagccaaaa
     1921 aattgcttct gttgacctga ttttctcggt aaaaaaccgt aaaagatatg tggctgtggc
     1981 gctaaaccac tggcaatcaa ggcagaaatt cctgcagagg tacctggaac agtcacaact
     2041 gcaatttctt cctcaatagc tgccttaact aaatcatgac cagggtctga aatgctaggc
     2101 aaaccggcat cagagacctg agcaatactt tgccctgctt tcaagaaacc aatcaaatca
     2161 ggaatttttt ccttggcatt gtgctcatga aaactgatct gcttggtgga aatgtcaaaa
     2221 tgcttgagca aaagccctgt attgcgcgta tcctcagcag caatccagtc cacttctttc
     2281 aaggtctgga tagcacgaaa agtcatatca tctagattgc caatcggcgt tgccactaga
     2341 tacagcttgc catagggaga ctgcccctta aaactttttt gaatttgcat gcttactccc
     2401 tgtataacaa ctcatcacag aacatacatt cttcgtcctg ctctcgacgt tgtccataaa
     2461 aatcattaca tacgtgaaat ccatcacggt aaatacgacg gacactttcg cgaacatgct
     2521 tggccttgac gggagcgtct gcttccacct cacccaagcg ttctcgcaac ttactatttt
     2581 ccaagcgaag agctgtattt tcttctacca agctcttgag atttttcttg atggcttcca
     2641 catcggctaa agttaccaat aattgttggg aaaaatcatc cagcgcgtca aataattctt
     2701 ttttgtccat aaaacagccc tttcctttct ttatcattca tttttgagtt tatatttctt
     2761 tcaagaccag atattccatg gcattttgaa agctgacatt agcttgccac atttttctag
     2821 cttctagtaa atcttgtaga atcactctta ctcttacctg caagaggtcc tgcccacaga
     2881 gaacttcaag aatccgtaaa acctgatcct gtttttcctt atcatctgcc aagttggcta
     2941 atttggcaac ctgtagataa ctttcttttt tcttagctac taaccaagtc agcaggcgtt
     3001 cactttcatc gaccaaggtc caaaaacttg cctgattagc caacttttct gcttcagctc
     3061 gcgattgact aaacttagct aaaagagtcg cttttttctt aacaagtccc atttgttcta
     3121 agagtaagat aagtttttct tcttgctttt taaagtggaa gatctgagtc cgacttcgga
     3181 ttgtcggtaa catcttttcc tcatcgctag tcaagaagaa aatataaact tcactctggg
     3241 gttcttcgat gaccttgagc agagaattgg ctgcgttggg atgcatttta tccgcttgct
     3301 cgatgataaa gacctgttgc tggctttcaa tccctgcttg agaaaactgt cccaccaatt
     3361 cccgaatacg ttctgtcttg atgacctgat tgactggctt aatcaaggtg acatctggaa
     3421 actcttcctg ttcaatcagc ttgcaacttc ggcatttctc acatggtaag acgccaactt
     3481 tatccgtaca aaagaggctc ttagctaaaa attgcgccat ttccaagctt ccaaagaaac
     3541 ctgaaaagag ataggcgtga ttgagctggt cttgttctaa gatacggaca aaacggtcaa
     3601 actgagctgg ttgccaagcc tttagttgat cttgtttcat ttggccaagc ccattccgtc
     3661 aaacaagaca gccttggtag tttccacaac ttgctccaaa gggagactag catcaatctt
     3721 gacaatgcga tttccctctt tatccagaag agaaaggtag ccttgacgaa cttttttatg
     3781 caagtccaac ccttccaaat ccaaacgatt aacctcgcgg tcactattag cagcaatacg
     3841 agccagccct tcttccacct cgatgtcaaa atagagtgtc aaatcgggtt tgaggccatc
     3901 tgtcgcaaac tgattgagcc agtcaatggc ttcaatatct aagccacgac caaatccctg
     3961 ataggcaaca gaactatcga taaaacgatc catgatgacc aacttgccag cttcaagggc
     4021 tggaagaact ttttccacca aatgctgtct gcgactggca atatagagaa gtagctctgt
     4081 tttagcatcc atctgagtat gacttggatc caaaatcact tcccgaatct tctccccaat
     4141 caagactccg ccaggttcac gggtcgtcag cacctttact cctttttcct ctaaaattgg
     4201 tagcagagcc tctaaaacac tggtcttgcc tgctccctct ggtccctcaa gagagactaa
     4261 aaatcctttt gacatgtcta actcatttct tttttactac ttctattcta tcaaaaaaat
     4321 aggggtttgt gacaatcttt ttgtcttctc atttcatact caatgaaaat caaagagcaa
     4381 actaggaagc tagccgcagg ctgtacttga gtacggcaag gtgaagctga cgcagtttga
     4441 atttgatttt cgaagagtat cagccaccat aaaagaggca gataaaacta cctcttattt
     4501 acctagttct tgtgttcgtt tataggcttg atgaactgcc tccatgactg tgcctcgaaa
     4561 agcatgcgct tctaggcttg ctacgccagc aatagtcgaa ccgcctggac tacaaacttg
     4621 atctttcaaa actccaggat gttgctggct ttctaggacc aattgcccag ctcctaccac
     4681 agtttgggct gccattttca aggctgtttc tcgtggtaat cccgtctgaa cacctgcatc
     4741 tgccaaggcc tcaataaaga gatagacaaa ggctggtcca caacctgcaa gacctgtcgc
     4801 tgcattgatt aagctttctc ctaattcaac caagagacca gccttggcta aaagctgaca
     4861 aaagatctca ctgtcctcag ccctgcaatt aggagacaag gcataactaa tcactccttg
     4921 cccgatagaa gcaggggtat taggcatcat acgaataatt cggtgttggc ttgggataag
     4981 acttgctagt ttttctaagg tcaatccagc tgccatcgaa atcaaaagaa gactttctct
     5041 tttttcaagg atggtctggt attgagaaag cagttcagaa aactgagcag gcttaacacc
     5101 tagaaaaatc acatctgctt cttcgaatat ttcttcattg ttagaagtct gaccaccgaa
     5161 gttagcgatg aaagcatcca ccttgacttg actacgattg gcaaggagaa tctcatctga
     5221 cggtctagcc tgcaagacag acttggttaa actagcaccc atattcccca aaccgataaa
     5281 tccaatcttc atctcttact cccttatctg tccatcacca gtgaccacat acttgtagct
     5341 agtcaattcc ttcaagccca taggaccacg cgcgtgcaat ttctgagtag aaatccccat
     5401 ttcacaacca agaccaaatt gtcctccatc tgtgaaacga gttgaggcat taacatacac
     5461 cgctgcagag tccacttgat ctgtaaagta tgctgcagct tcagcatttt ccgtcacaat
     5521 ggcatccgaa tgatgggtac tgtgggattc aatatgcgca accgcttctt ctaaactgct
     5581 cacaacctta acagctagaa tatagtctaa aaactcggta tcaaagtctt gtgcttgagc
     5641 agcttgacct gaaacaaact ggcttgcttt gctatctagg cggaattgaa ttggttccaa
     5701 cccagcttct tttcgatctg caaccaacac ttgctccaag cgaggaagga agcttactgc
     5761 tttgttttca tgaaccagca gaacctccat ggcattacaa acagaaggac gactggtttt
     5821 agcattgttg atgatagaca gcgccttgtc ttcgtctgca tccttatcca catagacatg
     5881 gacaatccca gttcctgtct cgataacagg tacaatcgca ttctcaacca ctgcattgat
     5941 caagccagct cctccacgag gaatgagaag gtctagatag cccttggcct tcatcatagc
     6001 ataactactt tcacggctag tatcctccac cagttgaatc acatttggat gaatagtagt
     6061 cgtctccaag cccttcttca aggctgtgac aatggcatgg gttgtttgat aggcatcctt
     6121 accactacga agaacaaccg catttccact cttaagagtc aaagcagccg catcagacgt
     6181 cacatttgga cggctttcat agataatacc gatgacaccc atagctacac gtttttttgt
     6241 gataaccaaa ccattttcaa gctgacttgt ttctaaaact tcaccgattg gatctggtaa
     6301 ggcaaccact tcacgaattc ctcttgccat cgcttctata cgatctgcat ccaaataaag
     6361 acgatccaac atcacatctg agattttccc cttagccgct gccatatcga gggcattagc
     6421 cgctaaaatt tcctcagtag cagccactaa gtgatcagcc atggctagca aggcttggtt
     6481 tttcacttct tcactagctg tgttaatcga ttttttaaca gcctgtacct gttcaaattg
     6541 ttcttgtcta ctcaccatag tttacctcta aaattctgta aaaagtagtt ggatttcagg
     6601 agtaatggaa atccagtcgt cacggtaaat caagacaccc ttggcttttt gaaaacgcaa
     6661 catatcctcc aaagcagatg ctccaaattg cacgcgtcct tttccaagtg attttccact
     6721 ttccttatca aatactgtca cgatatcacc gtaagaaaag actccttctg cttcaacgat
     6781 accagataag agaagactct ttccatgttg agagagagct tccgcagccc ctttatcaac
     6841 ccaaatagaa ccttgactct gagcatagaa ggcaagccat tgtttctggg tacgaagccc
     6901 cttctcttga gcaacaaagt aagaaccatc ctcggtctcc tctgccgcct caaccatgga
     6961 atctgatttc aaggatgagc agatataaac aggaactcct gattccgtcg cgatagttgc
     7021 agccttgatt ttggttaaca tacccccagt tccgtttgac gaaccagctc caccagccat
     7081 atcaataatc tcacgattga tggtctcgat tctctccaag cgtttggctc ttggatctga
     7141 attaggattt ccagtataga gaccgtccac atctgtcaag aaaactaaaa ggtctgcttg
     7201 gaccatcgcc gctacttgag cacttagagt gtcattgtcc ccaaccttga gctcatcaat
     7261 aacgacacta tcattctcat tgatgatagg aattgcccca cggttgagca aaaccgacaa
     7321 agcctgatgg gcatttttat aacgacgctt atccacaaag tcatcttggg tcagcaagat
     7381 ttgtgcagaa acgatttgac gcaagagaag attggtcgta tattcttcca acaaaagtcc
     7441 ctgccctacc gctgctgaag cctgtttatc agcaatttta gtcggacgct ttttaaatcc
     7501 taaggctcca aaaccagccg caatggcacc tgaagacacc aaaatcaact catgaccagc
     7561 ctcgtgcagc atagccaact gctgggtaat atcctttacc ttactacgtg ataaacttcc
     7621 atcctcattt gtcagagaag aagtgcccac cttaaagaca atccgtttgt atttcatagt
     7681 ctcactccga ttattcatat ttatccatta taacatgaat aacaggaaat agaaaagagt
     7741 tgataggaaa aagaaggccc taaaaccttc ttttctacta ctattctgat tccgatttgt
     7801 ttacactcgt ttcagagctt tgtgaagttg aggatgtcaa atcttgacta gttgaagaat
     7861 ttgtaacact ttcatgttga ctcgtttctt tattttcaag atcctttttc actacttctt
     7921 tggattcttt tatttctgaa tgacttgtag ttttaattgt agcagatttc tcgatcggaa
     7981 catccactaa ccaggcacca cttgaatcca cagtatagcc ttctggtgtc ttaccattca
     8041 caagtaattg accattttct ttcaagaagt accatttatc cttgtcttta atccaaccta
     8101 tagctcgtga accacctgtc ttgtagaaat accaatcatt tgccttttta agccagcctt
     8161 gcttcatagc tcctgattct tctagatagt aatgatgtcc agcaacttct atctcacctg
     8221 tcttcatgat accagtagaa tccatatagt accaggcttc tttatctttt acccagcccg
     8281 ttttcatttc ccctgatgga gcaaagtaat accattgccc cttatattga agccaacctg
     8341 tcttcataga gccatcaaca tccaaataat accactgctc tttatcttga acccaaccaa
     8401 tttccatctg attttctttg ttaaaataat accagattcc atcaattttc ttccaatttt
     8461 tagcagaagc accagagtct gtcaaataga accaatgatt gttccatttt ttccattgat
     8521 tctgtaacaa gatacccgtt tggttaaagt aataccattc accttcgatt tcattccaac
     8581 cgacagcata ctctcctgta gaatcaggcg cttgatacca ccagttccca tatgcactct
     8641 tatgccaacc agcttgaaaa cttggaatcg gcttgtagga tgttgaaata ttgacaaaac
     8701 cgtcttttcg aatatcaaaa actgttgcat catagtcttt gctggctgcg ttgattctct
     8761 caattcctcg ttctttgagc caattaacat actcactatc aacaccattt ttccaaggta
     8821 gactatccga agtttgaaca atcaaactcg gactcaaatt tttaatgaaa tccttggtat
     8881 ttgatttgtt ggtatcatgg tgatgattaa acttcatcaa atcaactttt ccaatgagag
     8941 gaccatactt gtcttctgct ccatgaacat tatctaaatc gcccccaagg taaattttct
     9001 tgccattgac tttcaccacg ctaatcaagg aattggaatt gtcatcccaa attttcttta
     9061 attcacccga tgaatcagtt tcattttcat aattatagag ctgaatatcc atgtccccaa
     9121 actgaaaatg agcatcccct tgtgtgatat tttgaataac tgaaacacct ttttctgcag
     9181 cagtctgtaa aaccttatca tagccataca gattatccca tagacgttca gaattagtaa
     9241 tacgactatc actatatttc ttaagataga ctcggtcaac tggataggta gacagtaatt
     9301 catcaacatt tccaatatga tcactgtggg tatgggtcac caaaataaaa tcaagttttt
     9361 ggacacccaa ttccttcaaa cgacgaaaga cacggtctgt tagaacatgc ttataagacg
     9421 tttcaattcc ttctctccat ggataacgag aatcacttcc atctgggaaa tcataatctt
     9481 ctcctgtatc caccatggca aaatgtccat tgctttcaag aataatcgca tcactgccac
     9541 cttcttgaac attgataaag tggattttat ttcctgaact ttcttgagcc tgaacattcc
     9601 cataccatga caaacctaaa aaagcgccta caagtgctaa actagttaat ttctttttca
     9661 ttcttacttt ctcaatctct ccaaggtttc cttaaaaatc tctgggatat ctgctttaaa
     9721 ttccaaggtc ttacctgttc tcggatgagt aaaacctaaa gtcttggcat gaagaaattg
     9781 tccatgtcct ttcaaagtct tgcgaggacc atagacctca tcaccagcga ctggatggcc
     9841 gatataagcc atgtggacac ggatttgatg agtgcgccct gtctccagtt gcaactctac
     9901 taagctataa tcgccaaagc gttccaagac gtgaaaacgc gtcactgcag gcttcccttt
     9961 agcagttaca gcctgtttct tacggtcttt ttcactccgg ccaatcggcg cttcaattac
    10021 accacgatca ttaggcagat ttccatgaac aatcgcccaa tatttgcgga gagacttttt
    10081 atctttgagt tcttgggcaa gtactagatg cgcatcatcg tttttagcaa tcatgagaag
    10141 acctgacgta tccttatcaa tacggtgaac aatccctgga cgcagaaccc cattgatacc
    10201 cgacaagtcc ttaatatgat acatgagggc atttactagg gttccactgg tatgaccagc
    10261 actcgggtgc acaaccattc cctgaggttt gttaacgaca gccacatcct catcttggta
    10321 gactatttct agcggaagat cctcagccac atactctaat acctctggtt ctggcacatg
    10381 gtaagtgacg acatcaccct cttggactgt gtatttagct ttcttgactt gaccattgac
    10441 caagacctgg cctgatttaa tttgttcatt cgcgagacta cgtgataatt ctgacaaatc
    10501 tgacaaagcc ttatccaaac gcagaccacc agtttcaatt ttaatttcca tttatttcct
    10561 cttttagcat tgcaatcaat aaaataatca ctccaaccgt cagatagcta tctgccacat
    10621 tgaaaattgc aaagttgata aagtcaaggt ggaacatatc cacaacaaag ccctgactga
    10681 ccctgtcaat aaagtttcca agaccacccg cgattattag agtcaaaccc aagaacatcc
    10741 agaatgagtc ctccatgtgt ttatgtaaat accaaatggc acctatcacg acaaccagag
    10801 taatgacagc gaataacagc tgctgatctt gtaagataga aaaggctgca cctcgatttt
    10861 gcaggtaggt caagctaacg aaattgggaa tccaggagcg cacttcaccc agtggaatct
    10921 gctggacgat ataggatttg accaactgat ccagcccaat taaaagcagt acaatgactg
    10981 ccactattgc tctttttttc atgatttcct cttttgatca aaatattctt gcatgacttc
    11041 tacgaagaga gtcccagctt gactaagctc cacttcttca cgtttaacat agaccatgcg
    11101 gttatctagg ttatccttga gacgaataac tgtaatgcca ttaacactgt cactatctaa
    11161 aaatccagaa cctgtcgcat aggcgtccgt ccgctccaaa ataccattca aggtggcacg
    11221 gtctgtcaca ttaaacatct gtgagctagc gctggtatcg acaaagttct ctgaataata
    11281 aaggtactcg tctttctctt gagtgaaacg aaccgttggt aaatccgcta aatcctccat
    11341 gactaattcc tctttctggg ctaaaggatg accctcacag agataaatat gggtatggaa
    11401 aggaatcaat tcgatgacct ccagacctaa cttttcaacc cgttgcataa tccccttttt
    11461 attttgattg ttgaggtaga taatcccaat ctcactatgc ccttgcgcca cttcatctaa
    11521 tatttgaaca gtagttgatt caaaaatacg gaagttctta tagtcaggat agcgctctga
    11581 aaaggccgta atagttggtg gtaagaagtc atagtgctgg ctagcaacgg aaaattcatc
    11641 tttttcttct tcaggattgg catactgatt ttgaaaaata tcaaatcctt taaccaattc
    11701 ttgcgctttt tcataaaatt ccatcccacg acgggtcaag aaagtccctg agctggtccg
    11761 acggaaaatc ttaaagccca actctttttc caaatcacga acagaaatag acagactcgg
    11821 ctgactaaca tacatctttt cagcagcttc acgaaaagta ccactattgg caatagccac
    11881 aacatagcgt aattgttgaa tgttcatctt ctacccccaa cttctttatc ttttcattat
    11941 accatatttt agaagttttc caaaaaggaa aaaagaacat cctattcttc ttaactatct
    12001 tcactatctg cctttctcac gccaatctta ttttcaaaat caattcaaaa aaataagtgg
    12061 ctacacacca cttcagtatc ggaaagaaaa acgttgacta tttgtgaaaa aagaaaatgc
    12121 cggaaaattc cgacattttt ttagtaagct aacttcctga aaataggagt aaccaaacat
    12181 cccagaaggc agtgatattg atgagaatat gaactagtat tggatagtag agatttttag
    12241 tcatgcgata caatagagct aaaatcagac ctccactagc ataaatgaaa aaagcaagag
    12301 gagttaaagc aaaattgata tgaatataac cgaaaataat agcagaaagc aaaacatctc
    12361 cgtaccaagg tgagtttttg aaaaaggttg tcataagcac acctcgataa atcaattcct
    12421 cagcaatagg ggcgatgaag caaacgatga gcaagaaata agggaactcc tgtctcccca
    12481 tcatttctac cgtttcattc aaagaaatct gatttgaaga cagggatatg aaatacgaaa
    12541 agaggaagtc agacatatat gaaatgatgt agcccagtaa aaggtagatg aagtacctca
    12601 gctgccactt gaaatgaaaa attttctttc ctgcaaaaac cagtagatag atgaccgcta
    12661 agaaaagaac tccgctctcc atcaaaagca gaatctgaaa aaattcacga cttgctggta
    12721 gatagggctt tgcgaggtga ttgaaaactc tccaaaacca agttgatttg taaaaaatta
    12781 aggacaatgc tagtaaaatt tgaatagccc gttttttcat attaaattct ctgctttctc
    12841 cacttatttc ttcatattac taataaattt tacttaaaat ctcgcagcac ttcctttgca
    12901 aagatgattg cctcctccaa tatatcctaa atcataggtg cctctgggac aaaatccatg
    12961 aaccggcaga gttaatactg gttctatttc ccaatcgtac ctaccattag gatttttacc
    13021 atatgaatct gctccacctt gtatcagctc taattcttca tttgttagat ttatattttt
    13081 tgtcattaaa atcatgatat atttcctcca ttattcttca gattagttga gtaatctgat
    13141 actcatacct acttacaaaa aaactattat attaagttgg ttttttaatt tgtctagttg
    13201 caacattgac aaacatagta tagcatatct ttgcgaaata tcctcttcaa atcatgaatt
    13261 gtcatcaaaa catcttaaac tataaaatca attagtctca agctttctat caatttcttc
    13321 tccaaaatat gctataataa tagcaaaaga taaagaagga agacctatga ttaaactact
    13381 agccttggat atggacggca ccctcctcaa tgaagccaag gaaatcccac aagctcacat
    13441 tactgctatt cacaaagcca ttgaaaaagg tgtcaaactg gttctctgta cgggtcgccc
    13501 ccttttcggt gtcctcccct actacaaaaa actgggactc gacctccaga atgagtatgt
    13561 gattgttaac aacggttgtt caactcacca gactagcgac tggggcttgg ttgactggca
    13621 agaacttagt ccagctgaca tcgaatacct ctatgacctt gctgaaaaga gtgatgttca
    13681 gttgacactt tttgacgagt cacattattt tgttctcggt ggaaagccca atcaagttat
    13741 tgaaaatgat gctaaactag tattttcaga cctgactgaa atttctcttg aggaagcgac
    13801 tagtggaaag ttccggatgt tccaaggtat gtttttagga acaaaagaac aaacagacga
    13861 ttttgagcag cgttttgctg aagagctttg ccaacgattc agtggagttc gttcgcagcc
    13921 tgtcatttat gaagcaatgc cacttggaac gacaaaggct actgctcttt cacgactagc
    13981 tgagattttg aagattgatt cctcagagat tatggccatg ggcgatgcta ataacgatat
    14041 cgaaatgctc cagtttgcag ggcttgggat tgcaatggga aatgccagcg attatgtcaa
    14101 atctcttgcg gatgccgtta cctcaagcaa cgaagaagac ggcgttgcgc gtgctattga
    14161 gaaatatatt ctataaaaaa gaaaagcaaa tagacagaag ttactgctat ttgctttttt
    14221 gctaatattt taaaatacgg actaatcaat agagaagaat agcgaatcat aaaaatcgat
    14281 ttactagatg ccatagtatc ttatagttgc taataagaag ttagtctagc agaatgaatc
    14341 tctcatttct cccacactaa tctgtaattt gtctatacat ttctggtctt ctatctcgaa
    14401 acaagcccca gtttaggcgt tcacttgctc ccttgtctag gttataagta gctaacagaa
    14461 cagcttcttc ttgtctttca gctcgttcta gaatagctcc tgtttcatcc gtcataaagg
    14521 aggaaccgta gaagtcaaga ctggaactct gtccgccatt ttcctcacta ggagtaacct
    14581 cctctaaacc ataacgattg gctgcgatga ctggaacaat attcgctgct gcgtgccctt
    14641 gcatagtacg ttgccagtga ccacaactat ctgtatccaa aattggctct gaaccgatag
    14701 ctgtaggata aaagagcaat tcagcaccat tcaatgcaag acagcgcgct gtttcaggga
    14761 accattgatc ccaacagata ccgataccaa tcttagcata gcgagtattc cagaccttga
    14821 aaccagtgtt accaggcgtg aaatagaatt tttcttgata ataatggtca tctggtatat
    14881 gggtctttcg ataaacgccc agcacttccc catctgcatc aatgacggca atagagttat
    14941 acaagacatt accatctttt tcatagaaac tgattggtaa aacaacttgt agttccttag
    15001 caagcaactt aaaatgctga atggcagtat tttccgctac agattgggca tactggtagt
    15061 agtcatactg acgttcctga cagaaatagg gatgttcaaa caactcgggc aagagaataa
    15121 tttgggctcc ttgctcagca gcctgacgta ctaaacgctc tgcggtttgg atatttgttg
    15181 ccacatcctt agcgcattgc atctgaatgg ttgcaactct tacatttctc atctttttct
    15241 cctattctgg aatttgttgg gtgatacagt ggatattgcc accacctaag agaatatctc
    15301 tggctggtat tccgacaact ttacggtctg ggaaacactt gctgaggata tctaaggcca
    15361 cttggtcgtt tacatcctca aactgtggaa ccaagacagc cttgttggcg atataaaagt
    15421 ttacgtagga agctgctagt cgttcacctg cgtatcgctc ttcttctcct tcttcataga
    15481 tgtagcctgg caaatcttct tctgtcacaa cttgtcgaac tgcagggata ggcaatttat
    15541 gaatggtgaa gtgacaacct tttgcatctg tttcctgttc taagagttcg agatctgctt
    15601 ttgacatggc atactgggga tcattttcgt catctgtcca agccaaaaca acctcagcag
    15661 gaccaacaaa ggcaacaaca ttatcgacgt gttcattggt ttcatcctga taaataccat
    15721 aaggaagcca aataactttt tcagcaccaa gactttctaa taatgtgttt tcaatctcct
    15781 ctttagtcaa gttaggattg cgaccaggac taagcaagca actttcagtt acgagaatag
    15841 ttccttgacc atcgctatgg attgcgcctc cttccagtac aaaaggttta gcatcataga
    15901 caggcctttc caaggcctca gcaaaacgac tggctacttg gtcatcctct tcataatctt
    15961 gataaagacc atcataggtg cctccccaag cattaaaggc ccaatccacg gctaatttct
    16021 tacctttatc attgacgaga atggttgggc cagtatcacg cgcccaggca tcattggtgg
    16081 gaatgtctaa ataaacaacc ttgtctccaa gataggattg ggcttcagat agataggcct
    16141 gctccaccaa aagatagact ctttcccctt ctgctatggt ctcgatgatc tgagtaaatg
    16201 ctcttttagc agcctttcct tgaaaaggcc atgatcctgg tcgagtcggc catatcatga
    16261 gggtaccatg atggggttcg tactctgctg gcatgtgata gcctaatttt tttggactgt
    16321 ccatcatgat aatctccctt taaagtcttg atagccaaaa gctttgagta agctacagtc
    16381 tccctgttcg tccatgagat agagacttgg caatccaata ccattaaagg tattattttt
    16441 gacaaaagaa taaatggcca tgtcttgaaa ataaagtctg tctccgattt ggactggatt
    16501 ttcaaaacta taatcaccaa tcacatcgcc agtcagacag gtattagaag aaagtctgta
    16561 ggtatgggct ttttcctgtg actcaaagcc atttctcaaa ggtggacgat agggcatctc
    16621 aagtacatca ggcatatggc aggtcgcaga ggcgtctaaa accaagattt ccataccgtt
    16681 ttctacaata tctaatacct cagttgctaa ataacccgca ttaagcgcaa tggcttcacc
    16741 aggctcgata tagatttcaa gattgtaagt ttttcggata cgcttgattt ctgaaatcag
    16801 caaatccaca tcgtaacctt ctcttgtaat atgatgacca ccacccatat tgagccattt
    16861 tacctcatgt aagtagggac caaactgttc ttctactgct ttcaaagttg tttgtaaatc
    16921 atctgctccc tgctcgcaaa gggtatgaaa atgaagtccg tcaaccaaat ctagcaaatc
    16981 gctcggaatc ttgtctatag taactccaaa gcgagaacca ggtgcacaag ggtcatagag
    17041 cgcgtgatct ccttgagttg aacactgagg gttgaggcgc aaaccaacac tgacaccagc
    17101 ctctcgacaa cgagccccat gcttacgcaa ctgtctctct gagttaaaga cgatatggtc
    17161 tgttatccca agcaattcct ccatgtcctc atccttgaaa gctggtgcaa aaacatggac
    17221 ttcaccagga aattcttccc ttgccaattt ggcctcatag agtccactag ctgtcgtacc
    17281 tgatagatac tggctaatca agggataagt tttgtagagg gaatatgcct tctgggcaag
    17341 caagaccttg caaccggcct cttcttgtac atattgtaga atgcggcaat tagcttctaa
    17401 cttggccaag tcaataacat aggctggtgt tggtacttgt tctaacttca ttagtccaac
    17461 atttgtggat tttcaaccac aacccatggc aaaccatact cattcaaagc ttccatgaat
    17521 ggatctggat ctaactcctc aaggttatac actccagctt gtttccaagt tccgttcatg
    17581 actaattttg tcccaatcat ggctggaacg cctgtcgtgt atgaaattgc ttgtgacccg
    17641 acttctgcat agcactcttg atggtcgcaa acattgtaga tgtagatagt cttttcaacg
    17701 ccatctttga cacctgtaaa gatacatcca atattggttt tacctacagt acgtggacca
    17761 aggctagcag gatctggaag caaggctttc aaaaattgaa ttggaacaat ttcttggccg
    17821 ttaaagttaa tggtatccgt acgaaggagt ccaacatttt caagacattt catgtgcgtc
    17881 aagtaagatt gaccaaaagt cataaagaaa cgaatgcgtt tgacacctgg aatgttcttg
    17941 gccaatgatt cgatttcttc atggtgaagg agatacatat ctttttgtcc aacttgaggg
    18001 aaatcatact cacgcttgat agacatagct tcgacttcga cccatttccc atcttcccag
    18061 taagaacctg gcgcagaaac ctcacggaga ttaatttctg gattaaagtt ggttgcaaat
    18121 ggataaccgt ggtcaccgcc attacagtct aaaatgtcga tataatggat ttcatcaaaa
    18181 tagtgtttga gggcataagc tgaaaagaca ctagttacac ctgggtcaaa accagaacca
    18241 agaagagcag tcaagcctgc ttctttgaat ttctcttgat aagcccactg ccatgagtag
    18301 tcaaagtagg ctgtaaaacc aagttcctta caacgttttt cgtagatagc acgccactca
    18361 gggtcttctg tgtcttctgc ttcgtagttg gctgtatcga tatagtgaac acctgttgcc
    18421 aaacaagcat ccataatggt taaatcttga taaggcagag ctacattcaa aacagcttct
    18481 ggtttgtagc tttcaatcag agcaatcact tcttcaacct tgtcagcatc aagagcagct
    18541 gtctcaatct ttgtacttgt tttgccttcc agtttagctt tcaagtcatc gcattttgac
    18601 ttggtacggc tagcaatcat aatctctgta aatgtttcgc tatcttgaca aatctttgaa
    18661 atagcaactt gggcaacgcc cccacaacca ataactagta aacgactcat ttttttcctt
    18721 cctcttcttc taaaatgtcc tcaacatact tgggcaacat aaaggctccc acgtgtaagt
    18781 ttgcagtgta gtattctgtg aaaagctggc gttttttcca gccttccttg tcaaaatctt
    18841 tgacagggtg gtattttttc gatgcaaatc caaacaacca atagccagct gggctagttg
    18901 gaatatgggc ctgataaacc cgactgattg gaaaggcttg attgaccttg cggtgcatgc
    18961 ttcggcaggc cgactcatcc tcgtcaaaga acggactccc atgctggtaa atcatgatgc
    19021 cgtcttcctt cagagctcga taactattgc cgtagaattc cttggtaaag agtccttccg
    19081 tatggccaaa tggatctgtc gcatcgttga tgataatatc atagtcatat tcgcagtttc
    19141 gcaaaaagcg tagcccattt tggtagtaaa tggtaacacg aggatcatct aggcctgcag
    19201 caaagtctgg gaaatactca cgacagacct cgaccaacat ctcatccggt tccacgatat
    19261 cgatttgttc cagttcagga tagagtgtta atacttgggc aacaccgccg tcaccacccc
    19321 caataaccaa tactttcttt ggatttgggt ggacagccat gggaacgtga acggtcattt
    19381 cattgtagac gaaatcatcc gcatctgaga acaagacatg gccatttaaa atcagtattt
    19441 tcccaaaagc tggcgtatcc aagacttcga tatcctgcca ttcacttttt ccagcgtaaa
    19501 gttgcttggc tgttctcaga gacaatttga catctggagt atgaacttca gaaaaccata
    19561 aatccatcta tttctcctta tattatattt agcgcagtta gctactgcca aagcccaagt
    19621 ggtatacttg gaataagcca ctgtggatta gttcatttcc tccaatcgct tgacgatttc
    19681 cgaaagggtc taaccacagc tttttgtttc aattggtaat gagtttgata acgcatagac
    19741 gttttatctc gtctaaggta acaaggcaaa aagttcgtgg ataaccaagt agacttgaaa
    19801 tactatatct ggaggtactc ccatgcttta tgtgggcatt gatgtcgcta aaaataaaca
    19861 cgatgttaca gccttgaatg ttcgaggaaa actgttctta aaccactcac tttttcaaat
    19921 aataaagctg gttttgaact cttagatctg tctcttcgac aactcaacca agactgtctc
    19981 atcgctcttg aaaataccgg acattatgcc tttaatctac tgaacttcct gcatgaacaa
    20041 ggatataaag tttacaccta cactcctttg ctcatcaagg aatttgccaa atcattatca
    20101 cttcgcaaga ctaaaacgga taagaaagac gctcatggca tcgctcttaa acttctttct
    20161 gaccccaatc gtgaacaatt tcaacacgat aatcggcaag tagaactaaa aatactg
//
LOCUS       DAVBIC010000044        18957 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.044, whole genome shotgun sequence.
ACCESSION   DAVBIC010000044 DAVBIC010000000
VERSION     DAVBIC010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18957)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18957)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18957
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.044"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            complement(21..1376)
                     /gene="rlmD"
                     /locus_tag="VQ664_001581"
     CDS             complement(21..1376)
                     /gene="rlmD"
                     /locus_tag="VQ664_001581"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HET2789716.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCTIYNECGGCQIMHLHYDKQLEFKTDLLHQ
                     ALKKFAPAGYENYEIRPTIGMQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELK
                     DCLVQDKETQVIANRLAELLTYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNR
                     QLNLTQLVKELVKDFPEVVTVAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSL
                     SPRAFYQLNPEQTEVLYSEAVKALDVDKEDHLIDAYCGVGTIGFAFAKKVKTLRGMDI
                     IPEAIEDAKRNAKRMGFDNTHYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLL
                     DTILTYVPEKMVYISCNVSTLARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVKLIKK
                     V"
     gene            1414..2190
                     /gene="recX"
                     /locus_tag="VQ664_001582"
     CDS             1414..2190
                     /gene="recX"
                     /locus_tag="VQ664_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HET2789717.1"
                     /translation="MKITKLEKKKRLYLMELDNGDKCYITEDTIVRFMLSRDKVISEE
                     ELKEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDKNIVSQVIANLKEDKW
                     INDGQYAYAIINANQLSGDKGPYVLTQKLAQKGISKSTIEEILNDFDFSEVAQRVANK
                     LLKKYEGKLPARALQDKIIQNLTNKGFSYFDAKIAFDELDSQVDEETTQELIFKELDK
                     QYTKYARKYEGYKLKQRLTQVLARKGYDFSDIASALREYL"
     gene            2279..2812
                     /locus_tag="VQ664_001583"
     CDS             2279..2812
                     /locus_tag="VQ664_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HET2789718.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
     gene            complement(3252..4008)
                     /locus_tag="VQ664_001584"
                     /pseudo
     CDS             complement(3252..4008)
                     /locus_tag="VQ664_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567550.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
     gene            complement(4146..5768)
                     /gene="groL"
                     /locus_tag="VQ664_001585"
     CDS             complement(4146..5768)
                     /gene="groL"
                     /locus_tag="VQ664_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HET2789719.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEATGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            complement(5784..6068)
                     /gene="groES"
                     /locus_tag="VQ664_001586"
     CDS             complement(5784..6068)
                     /gene="groES"
                     /locus_tag="VQ664_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HET2789720.1"
                     /translation="MLKPLGDRVVLKIEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            complement(6338..6733)
                     /locus_tag="VQ664_001587"
     CDS             complement(6338..6733)
                     /locus_tag="VQ664_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HET2789721.1"
                     /translation="MYNKVIMIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EADFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            complement(6811..7572)
                     /locus_tag="VQ664_001588"
     CDS             complement(6811..7572)
                     /locus_tag="VQ664_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HET2789722.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEILKS
                     EFAVSFPNQTVWTFPLDVTDMVMVKTVCSDILETIGRIDILVNNAGLALDLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMIKVNQGHIINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMIHKK"
     gene            complement(7605..8231)
                     /locus_tag="VQ664_001589"
     CDS             complement(7605..8231)
                     /locus_tag="VQ664_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HET2789723.1"
                     /translation="MIFTYNKEHVSDVLMVIVKNSGDAKLNVERKGKVARVFLKENGE
                     TVAWNIFEVSSLFEIAERGQVFLSDEQVARLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKIVQIVAGAPNARVGLKTIVALPGAMMPKGNFIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDPAKHWTA"
     gene            complement(8247..8564)
                     /locus_tag="VQ664_001590"
     CDS             complement(8247..8564)
                     /locus_tag="VQ664_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HET2789724.1"
                     /translation="MIQPASLEELASLVEKAGKKVFLFVADWCGDCRYIYPALPEIEE
                     TNPEFTFIRMDRDQYMDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKEQINDFLA
                     GLK"
     gene            complement(8561..8860)
                     /locus_tag="VQ664_001591"
     CDS             complement(8561..8860)
                     /locus_tag="VQ664_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HET2789725.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDRKLMKTQEELTE
                     IVRDHFSDMGEIATLYVQVYESSLESLVGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            complement(9145..9336)
                     /locus_tag="VQ664_001592"
     CDS             complement(9145..9336)
                     /locus_tag="VQ664_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HET2789726.1"
                     /translation="MYYSVDDVVSNAFKKRMILDSFFAFNCSGTMKVSTWVYDKGEWY
                     YVSSSGSMIANDWVKDNGK"
     gene            complement(9497..10171)
                     /locus_tag="VQ664_001593"
     CDS             complement(9497..10171)
                     /locus_tag="VQ664_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789727.1"
                     /translation="MKKKAFGIVLLVLAAWILLQGNFGIPSLDGKIWPLLGIVFFAYK
                     SIESILRRHLTSAVFTGLLALIIANYAYDLLPVTNHSLIWASILVVLGVGYLTHSSKF
                     WNEKKWWYNGKKTVVTDKEVAFGSGTFYKQDQDLVDDQVEVAFGDAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGAAKADAPVAPTSKTLTIRGDVAFGKL
                     EIVYVK"
     gene            complement(10177..10623)
                     /locus_tag="VQ664_001594"
     CDS             complement(10177..10623)
                     /locus_tag="VQ664_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2789728.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKAPRLTF
                     YKGTGEYYLDLSEILFFETEGSKIYAHNQKEAYEVRLKLYELESILPRYFNRVSKSTI
                     ANIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            complement(10725..11240)
                     /locus_tag="VQ664_001595"
     CDS             complement(10725..11240)
                     /locus_tag="VQ664_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HET2789729.1"
                     /translation="MKNYQEWYRNISSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVCVLIPASGFVALSLFRKKINHPRPYETWDICPLLDKDSSGRSM
                     PSRHVFSATIISMACLHASLPIGLVCLIFSALLGLVRVLGGVHYPKDVLVGYACGLVW
                     GFLFFLFLHVS"
     gene            complement(11237..11599)
                     /locus_tag="VQ664_001596"
     CDS             complement(11237..11599)
                     /locus_tag="VQ664_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 family protein"
                     /protein_id="HET2789730.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGKAESVHQVTSWLTGYEVS
                     DVLACLDRDVTYGDFFRQAPYYVPERIAITGKICSVRIEEIDDPLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            complement(11665..13524)
                     /locus_tag="VQ664_001597"
                     /pseudo
     CDS             complement(11665..13524)
                     /locus_tag="VQ664_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001850459.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
     gene            complement(13541..14011)
                     /locus_tag="VQ664_001598"
     CDS             complement(13541..14011)
                     /locus_tag="VQ664_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HET2789731.1"
                     /translation="MDKPMLVFKRFGHQIHLMVQKEAKRCGIEFMGGPQGQVVHFLDN
                     REKNQDLVLIKDIEQELNITKSVASNLVKRIVQNGLVELEASPVDKRAKFVRLTDKAR
                     SQMQQVKAFFERIDKQLMEDIDEDELLIFEKVLGQLQANIKGIGGENKEISQKN"
     gene            complement(14135..14851)
                     /locus_tag="VQ664_001599"
     CDS             complement(14135..14851)
                     /locus_tag="VQ664_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET2789732.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            complement(15732..17141)
                     /gene="ply"
                     /locus_tag="VQ664_001600"
     CDS             complement(15732..17141)
                     /gene="ply"
                     /locus_tag="VQ664_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HET2789733.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQHEKITAHSMEQ
                     LKVKFGSDFEKIGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLRQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFESLIKGVAPQTEW
                     KQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTSFL
                     RDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWDELSYDHQGKEVLTP
                     KAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRKRT
                     ISIWGTTLYPQVEDKVEND"
     gene            complement(17152..17484)
                     /locus_tag="VQ664_001601"
     CDS             complement(17152..17484)
                     /locus_tag="VQ664_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789734.1"
                     /translation="MYICIDNSMTKNKELVKNQTFKPALLTRRLVKNFMIEEPDLARN
                     PFTRPTLIDLDKVFMLDNTVIPTSYLARRRRNVSEELYEEILDYLVQPRLISLNKSEF
                     MQLNPGTY"
     gene            complement(17555..18163)
                     /locus_tag="VQ664_001602"
     CDS             complement(17555..18163)
                     /locus_tag="VQ664_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789735.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSLLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            complement(18176..18634)
                     /locus_tag="VQ664_001603"
     CDS             complement(18176..18634)
                     /locus_tag="VQ664_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HET2789736.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
     gene            18759..18869
                     /locus_tag="VQ664_001604"
                     /pseudo
     CDS             18759..18869
                     /locus_tag="VQ664_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            18868..18957
                     /locus_tag="VQ664_001605"
                     /pseudo
     CDS             18868..18957
                     /locus_tag="VQ664_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558195.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
BASE COUNT         5581 a         4204 c         3452 g         5720 t
ORIGIN      
        1 atgttttgtc aacacctttt ttaaactttt tttattaatt ttacaacagc ttcagttcga
       61 gctgtatgtg ggaacatatc gaccgactgg atataatgaa gatcatagac ttctactaag
      121 cgtaccaaat cacgagccaa ggtcgaaaca ttacaagaaa tataaaccat tttttctggt
      181 acataagtaa gaatagtatc taataactta tcatccagac ctgtacgtgg tgggtcaaca
      241 atcaaagcat ctgctcggta gccttccttg taccaacgag gaataatctc ttctgccgtt
      301 ccagcttcat aatgagtatt gtcaaatccc attcttttag catttcgctt ggcatcttca
      361 atagcttctg gaataatatc catacctctg agtgttttta ctttctttgc aaaggcaaat
      421 ccaatcgttc caactccaca ataagcgtca atcaaatggt cttctttatc aacatccagc
      481 gcttttactg cttcgctata gaggacttct gtttgctcag gatttagttg ataaaaagct
      541 cgaggggata gtgaaaattc ataattgagt acaccttctt gaatactctc ttgcccccag
      601 ataatctctg tcttttcacc atatatctca ctggttttag ctgtatttgt attaacagct
      661 actgtcacaa cttctgggaa atctttaacc aactctttta ccaattgagt taaattaagc
      721 tggcggtttg taacaataat aatctgaacc tgtccggtct ttctcgcgcg tcggaccata
      781 atagtacgga cacctagaac ttttctctca tccgtgattg gaatctggtg ataagtaagt
      841 aattctgcta agcgattagc aatcacttgg gtttccttat cttgtaccag gcagtctttc
      901 aactctacta aatagtgaga gttttgtgca tataagcccg ccttgacctg atttttaaat
      961 tttcgagtct gaaattgtaa cttagctctg taatattttg gttcctgcat tccaatagtt
     1021 ggacgaattt cataattttc atatcctgca ggagcaaatt ttttcagcgc ttgatgaagt
     1081 aagtccgtct tgaactccag ctgcttatca taatgcaggt gcatgatttg gcagcctccg
     1141 cattcattat aaatagtaca agatggcaca attcgaaatt tagacttctt gttgaccttc
     1201 agtaattttg cttcaacaaa gttgcgtcta atagaagtaa tctgacaata gatatcttcg
     1261 cctttgagag ctcctggtac aaagactaat gttttttggt aaaagccgat tccctcaccg
     1321 ttaattccca tgcgcttgat ttttaatggt attttttgtt tcactttcag attcataccc
     1381 ctatcttatc acattttgag ttataataga gctatgaaaa tcacaaaact tgaaaagaaa
     1441 aaaagactct atctgatgga gcttgataat ggcgacaaat gctatatcac cgaagataca
     1501 attgttcgtt ttatgttatc gagagataag gtgataagcg aagaggaatt gaaagagatt
     1561 caagactttg ctcaattttc ttatggtaag aatctggccc tctaccactt atcctttaaa
     1621 gcacgcactg aaaaagaagt cagagaatat ctgaaaaaat acgatattga taaaaacatc
     1681 gtttctcaag ttattgctaa tcttaaagaa gataagtgga ttaatgatgg tcagtacgct
     1741 tatgctatca tcaatgccaa tcaactttca ggagacaagg gaccttatgt actgactcag
     1801 aaattagcac aaaaaggaat ttcaaaatct actatagaag aaatcttgaa tgattttgat
     1861 ttttcggaag ttgctcaacg tgtagccaat aaactattga aaaaatatga gggaaaactt
     1921 ccagctcgtg ccctgcaaga taagattatc cagaacttga ctaacaaggg cttctcttat
     1981 tttgatgcta aaattgcctt tgacgaattg gatagtcaag ttgatgaaga aacgactcag
     2041 gaactcatct tcaaggaact tgataagcaa tatactaagt atgcccgaaa gtatgaagga
     2101 tacaaactga agcagcgttt aactcaagtt ttagcacgaa agggctacga tttttcggat
     2161 atagcaagcg ctcttagaga atatctttaa tatttccaag tgaaattcac agattttagg
     2221 taattttatg gtacaatagt aaatgataaa cttataaatt gtagaaagtt ggttagttat
     2281 gaagcttcca aaagaaggcg actttattac aattcaaagt tataagcatg atgggagtct
     2341 ccaccgaact tggcgggaca ccatggtact aaaaacaaca gaaaacgcca ttattggtgt
     2401 caacgatcat acacttgtta ccgaaagtga tggtcgtcgt tgggtcactc gagaaccggc
     2461 tattgtttac tttcacaaga aatattggtt taatatcatt gccatgattc gtgataatgg
     2521 aacttcttac tattgcaata tggctagccc ctactatctg gatgaagaag cactgaagta
     2581 tattgattac gatttggatg ttaaaatttt tacagatggg gaaaaacgtc tcttggacgt
     2641 tgaagagtac gagcgtcaca aacgcaaaat gaattattct gatgacttgg actatatttt
     2701 aaaagaacat gtcaaaattc ttgttgattg gattaacaat ggacgtggtc ctttctcaga
     2761 agcctatgta aacatttggt acaagcgcta tgtagaacta aagaatcggt aaagttgtca
     2821 aaggtcagga acaaaatcct gaccttgttt ttttggtagt ataaaataaa ttgtgtaaac
     2881 acaaaaagga ataaatccat tatagcagag ttacaacaca tttctataaa gaaatttatt
     2941 cctacgactc agtttggcat gcttaacttc ctaactcaaa aacaaagcat cgattaattt
     3001 atccgttctt cttttgaaac agatttgaac tgataattgc tcgttttaat ttaagaagct
     3061 cttttgagca aaacttcatt tttttaagag tccaacaatt tctgtctatc gcttttctac
     3121 tagcaaaaaa cctcccttga ggcaagtttt catttatata tctaatttcg taacagtata
     3181 gtaaaatgaa ataaggacag tcaaatcgat ttctaacaat gttttagaag tagaggtgta
     3241 ctattctagt ttcaatctac tataaatttg atatgagaat agtctttctc aacatcctta
     3301 tccaacaagc atgctgtggc gtccttctta acttgaacca ggtcaatatt ctgggcttgg
     3361 gctgccatag acgcagccac aataacattg acgatagata tcatactcct cacacatctc
     3421 tactgaacgt ttgtagcctt gatttttctt gaaatcgttg ggaagatagt gggtcgtgta
     3481 aattttttgc acatcgattc cgatgctatt gatggtttga gaattcttat gaggactgat
     3541 ggtcaaggct gaaccaaagt agtcaaagcc caagtccata gccacttgcg ctgttttatc
     3601 cagtcggtag tcaaaacaaa ccttgcaacg gtcgccacct tcgggctcct cctctagtcc
     3661 cctaactagt tttcggtatt aattgggttc gtagggagct tctaggtact gaaccgtatt
     3721 tcctgtccga tcattaaaat cactaacaaa tttcttgatg acatagaccc gcttatggta
     3781 ttctactttg ggatggatat tagaattggc aaaatagatg gtcacatctg catacttggt
     3841 caaatattct agtgtatagg tactacaagg ggcacagcaa acatgcacga gaatggttgg
     3901 ccgctgctca tttttctccc atgcttgtac cattttctgc atgacacggt cataattaat
     3961 cttctgattg gggggcatct tgcacagaat ttcttctaca tcgatcatgt tcttctcctt
     4021 tttctagtct tattttatca tataagttag aagagctcaa atcaatttag aagtgaatat
     4081 tataaaaaga agggttagtc attccctcct tttgtgtttt ttataagttg ttttctatag
     4141 aaagcttaca tcatcccgcc catcatactt ggatccattg ctggagctgg ggctactggt
     4201 tctggtttat tggctacgac tgcttctgtt gtcaaaatca agctggctac agatgctgca
     4261 ttttgtaggg ctgaacgact cactttaact ggatcaatga taccttgatc aatcatgtta
     4321 acccactcgc cagttgctgc gttgaatcct ataccaagct cagcattttt caaacgatcg
     4381 ataacgatag atccttcaaa tcctgcattg tgagcaattt gacgaacggg ttcttccaaa
     4441 gcacggagaa caatattacg tcctgttgct tcatctcctg tcaattccaa ggtagcaaca
     4501 gctggaatca cattggcaag agctgttcca ccacctgcaa caataccttc ttcaacagct
     4561 gcacgagtag cgttgagggc atcttcaatg cggagtttca tttctttcaa ctcagtttca
     4621 gttgcggctc cgaccttaat aaccgctaca ccacctgaca atttggccaa gcgttcttgc
     4681 aatttttcac ggtcaaattc agaagttgta gtttcgattt gagacttgat aaccgcaaca
     4741 cggtgagaaa tcgcttcagg atttcctgca ccttctacaa taaccgtgct atctttgtcc
     4801 acggtcactc tcgctgcttg accaagagct tcaattgtcg catctttcaa ctcaagacca
     4861 aggtcttctg tgataactgt tccgcctgtt aagatggcga tatcttcaag catggctttg
     4921 cgacggtcac caaaaccagg tgccttgact gctactacgt tgaaggttcc acgaatcttg
     4981 ttcaaaacaa gagttggaag agcctcgcca tccacatcat ccgcaataat caagagtgga
     5041 cgattgcttt ggagaatgct ttccaaaagt ggcaagattt cttggatatt ggaaattttc
     5101 ttgtctgtaa tcaaaatgta cggattttca aggtcagcca ccattttttc gctatcagtc
     5161 accatgtact gtgaaaggta accacggtca aactgcattc cttctacgac ttcaagctct
     5221 gtttccatac cacgtgactc ttcgatggtg atgacaccgt ctttgccaac tttttccatt
     5281 gcttcagaga tgtactcacc aactttttca gaacgagaag atacggctgc aacttgagcg
     5341 atagcttctt tattggcaac agggatggcg ttgtttttca aagcttcaac tgctgcggca
     5401 actgctgttt caatcccacg acgaataccg attggatttg cacctgctgt gacgtttttg
     5461 attccttcac ggacgattgc ttgggtcaaa acagttgcag ttgtagttcc atcacctgcg
     5521 atatcattgg tttttgaagc cacttctgat accaatttgg cacccatatt ttcaaaatgg
     5581 tcttctaatt caatttcttt ggcaatagtc acaccgtcat tggtaatcaa tggtgagcca
     5641 aatgattttt caagaacgac attgcgacct tttggtccca aggttacttt aacagtgtct
     5701 gcaaggatat cgacaccacg gaccatagct gaacgggcat ctgatgaaaa tttaatttct
     5761 tttgacatac ttactttctc cttctattct tcaatgattg ccaagatgtt agcttcgcct
     5821 acgatgatgt acttttcatc gccatctttg acatcaagac ctgcgtgggc ttcaactaag
     5881 acacggtctc cagttttaac acttggagca accaagtcac cgttcaaggt acgaacacct
     5941 tgtccagtag ccacaacttg ggctgttttg gttttttctt gggctgaacc tgcgagaaca
     6001 aagcccccaa cggtttgttc tttttcttct atttttaaga ccacacggtc ccctaatggt
     6061 ttcaacatct gatttcctcc ataatgagat agatattatt agcgctcttt atacctgagt
     6121 gctaattcat agttctattg tatcacttag tcagaaataa tcaagaaaaa agtctgactt
     6181 tctcaagata aaaagcctga gaccaactca gactttttaa tgtttatact caatgaaaat
     6241 caaagagcaa actaggaagc tagccgcaag ctgctcaaag cattgctttg atgttgtgga
     6301 taaagctaac gtggtttgaa gagattttcg aagagtatta aaatggcaat tcttcctctt
     6361 ccaagactaa atctgccaaa tcttggcctg cattattttc acgcatggca cgttgagcac
     6421 gactttccaa gagttggaat cctgttacaa gtacttcggt cacgtagttc atttggccat
     6481 ttttctcaaa gcgacgggta cgcaattctc catcaacgga aatgagacta cctttggttg
     6541 cgtagcttgc caaagtttct gctagtctgc cccataggac catattgaca aaatcagctt
     6601 cacgttcacc gttttggtct ttgtaacgac ggttcacagc gatagttgct cgcgctaccg
     6661 acttgtcatt gttggttttg tgcaattctg gtgtagacgt taaacgccca atcatgataa
     6721 ctttattata catattttct tcctcctact tatctattcg taggaaatca aaaaaagtta
     6781 cagaaatttg taacttttcg aggaaatttc ttatttttta tgaatcatga aacctgtcgc
     6841 ctgttgattg gccataatgg tcatatctgt aatctgaaca cggcgaggct gactggtcac
     6901 atagactact gtgtctgcaa tatcctgagc ttgcaaggct tctattcctt ggtaaacgga
     6961 cgcagctcgc tctttatcac catgaaaacg aacagttgag aaatctgttt cgacaatccc
     7021 aggctgaatg gttgtcacct tgatatccgt tgcgatggta tcaattcgca gtccatccga
     7081 aaaggtctta accgcagcct tggtagctga gtaaacagcg gcaccagcat aggcgtagat
     7141 tcctgcggtt gaccccatat tgataatatg accttgattg acttttatca ttgctggcaa
     7201 gaaacagcga gtaaccgcca tcagaccttt aacattggta tccaacatgg tcaacatatc
     7261 caactcctca tagtcttgat agggagccaa gtcaagagcc agtccggcgt tgttgaccaa
     7321 gatatcaatc ctccctatcg tttctagaat atcagagcaa acagtcttca ccatgaccat
     7381 atccgtcaca tctagtggaa aagtccagac ggtttgattt ggaaagctta ctgcaaactc
     7441 cgacttgagg atttctaatc tgtctatccg tcgtcctgtt agaacgacat cctcaccctg
     7501 ctccagataa gcacgcgcaa tcgcttcacc gattcctgag gttgctcccg taatcactac
     7561 attttttgcc atcttatttc cttctatcag atgctgacaa gttcctaggc agtccagtgt
     7621 ttcgctgggt cgaacggtgt tccgacaact tggtcttctg ataattcaag caccccacgt
     7681 ttttgcggag catttggcaa atgcaattca cgaggactac acatcatccc aaaactcttt
     7741 tcaccacgaa gttcgcctgg gaaaatgaaa ttcccttttg gcatcatggc accaggaaga
     7801 gccacaatgg ttttcaaccc aacacgcgca ttaggtgctc ctgcaacgat ttgcactatc
     7861 ttgtcacttg cgactgcaac ttggcagatg ttgaggtggt cactgtctgg atgagctacc
     7921 atctcgacaa tttcaccaac aacaaactta ggttccttat cattaacaat ttcttctgta
     7981 aaaccttccg cctgtaattc ttggttcaaa cgagcgactt gctcatctga taaaaagact
     8041 tgaccgcgct ctgcaatttc aaacaagctc gaaacctcaa aaatgttcca agccactgtt
     8101 tccccatttt ctttgaggaa aacacgggct accttgcctt tgcgttccac attcagtttg
     8161 gcatctccgc tatttttcac gatgaccata aggacatcac tgacatgttc tttgttatac
     8221 gtaaaaatca ttgtttcctt tttctcctat ttcaatcctg ctaaaaaatc gttaatttgc
     8281 tccttacttt tacggtcgcg attgacaaaa cgaccgattt ccttgtcctt ttctagaaca
     8341 acaaggctag gaattccgta aacatcccag agtttggcca aatccatata ctgatctcgg
     8401 tccattcgaa taaaggtgaa ctctggattg gtctcttcaa tctctggtaa ggcaggataa
     8461 atataacgac aatcgccaca ccagtctgcc acaaaaagga agaccttctt gcccgctttt
     8521 tccactaaag atgctaattc ttctaaactt gctggctgta tcataagact tcctcctcat
     8581 agactaggtc ttcattttca tagacaaagg tataatgacg gccatcctca aaaatgacgc
     8641 caccaaccaa gctctccaga ctgctttcgt aaacttgaac ataaagggtc gcaatttccc
     8701 ccatgtcgga aaaatggtct cgcacaatct ctgtcaactc ttcctgagtc ttcatgagct
     8761 tacggtcatc tgcaactttt ttcgtagcaa gagcaaggct tccgatacct agcagagcca
     8821 agcctgccat ccacattttt ttagctttca taccattcat tttaacacaa aaaaggcttc
     8881 aggacaaatg aggaagcagc agaaaagcaa gtaaaaagcc tcttccttta aggaaaaaga
     8941 cttcttatac taagagcaaa ctaggaagct agccgcaggc tgctcaaaac acggttttga
     9001 ggttgtagat aaggcgacgt tgacgtggtt tgaagagatt ttcaaagagt attattctta
     9061 ttgccaggca cctaagttgc caacgtagta actatcaggt gtgtaggtat tgcgaagcat
     9121 cttacctgat gaagccagat aatactactt gccattgtct ttgacccaat cattcgcaat
     9181 catggaacca gaagaactta cataatacca ttctcccttg tcataaaccc aagtactgac
     9241 tttcatggtt cctgagcaat taaaggcaaa aaaactgtcc aatatcattc gttttttaaa
     9301 agcatttgac actacatcat ctacgctgta gtacatagat acatcaaacg taaaagccaa
     9361 aatatcgaaa aatatacaac ttttaaaggc agcatttcat tttttaaagt ctaacaacca
     9421 tagaactgaa atcagagcaa ggcatcaatt tcctactctt agtacgtcta ttttgatggt
     9481 tgaagtgaag atttttttat ttaacgtaga caatttccaa cttcccaaaa gccacatctc
     9541 cacggatagt caaggttttg ctggttgggg ctacaggagc gtcagcctta gctgcaccaa
     9601 aggaggtttc tactttcaaa tctacacgcc agtgttgtgg aacatagacg gttgcattcc
     9661 cgaaggccac ttcaatattt aaagttgcaa aatcacctag catctctgca ttatcatagt
     9721 agattttagc atccccaaaa gcgacttcca cttggtcatc tacgagatct tgatcttgct
     9781 tatagaaggt cccgctacca aaagcgactt ccttatccgt gacgactgtt tttttcccat
     9841 tgtaccacca ttttttttca ttccagaact tacttgaatg cgtcagataa ccaacaccaa
     9901 gtaccaccaa gatgctagcc caaataagag aatgattggt aactggtaac aagtcataag
     9961 cgtaatttgc aatgatgagc gccagtaaac ctgtaaaaac tgccgaagtg agatgacgtc
    10021 taaggatgga ctcaatggac ttataagcaa aaaaaacaat acctagtaaa ggccatattt
    10081 taccatccaa agaaggaatt ccaaaattcc cttgcagcaa gatccaagct gctaaaacca
    10141 acaaaacaat accaaatgct ttctttttca tgttttttac ctcatgtttc ttagattttc
    10201 ttttaggagg gattggtaat gccgtgagac atgaacctcc ttgtgcgtct gataaaagga
    10261 aatggtgccc gttcctgaaa aggacttgtc cactgagtaa atctgacgga tgtttgcgat
    10321 cgttgacttg gaaactcgat taaaatagcg aggcaagata gactccaact catagagctt
    10381 gaggcgaacc tcataagctt ccttctggtt atgagcgtag atcttgctcc cttctgtttc
    10441 aaagaagaga atttctgaca ggtctagata atattcacct gtccccttgt aaaaagtcaa
    10501 cctcggagcc tttgactctt gcaagagccg ttgcaagtct gcaatttcat ctgtcaaagt
    10561 gggggtcttg atgacaattt cagtctcctc taaattgccg tcaatctcaa ttcgtaactt
    10621 catcacatct cctttctgac tctactatat caaagctaag ttaggaatac aagggcaaaa
    10681 aagcaagtgg tcaatttgaa gcagtaagtg gttgtaggac tagcttaact tacatgtaag
    10741 aataggaaga aaaggaatcc ccacaccaaa ccacaagcat agccaaccaa gacatccttg
    10801 ggataatgaa caccccctaa aaccctcacc aaccccagca aagctgaaaa gatcaagcat
    10861 actaagccaa taggtagact agcatgcaga caggccatgg agatgatagt tgccgaaaag
    10921 acatggcgac tgggcatcga ccgtcccgaa ctatccttat caagaagggg acagatatcc
    10981 caagtttcat aaggtctcgg gtgattgatt ttcttacgaa acagggacaa ggccacaaaa
    11041 cctgatgcag gaataagcac acaaacccca acttgctgac caagtcctag ttgcaggtaa
    11101 gtggtgacta gcaagatcag atagaccagg ggcatggcga ctgtcatcaa acgattgaaa
    11161 ctgcgtaata ggaataaaag aattggacga ctagttagtc tggagctgat atttcgatac
    11221 cattcttgat aatttttcat ttatgcttct catacttttc tagaacttgt tgagatgttt
    11281 tccccttggc aagccaatcc actagcttgt ccaagcgacg tatttcctgc atcagaggat
    11341 catcaatttc ctcaatacgg acactgcaaa tcttccctgt aattgcaatt cgttcaggga
    11401 cataatatgg tgcttgtcta aaaaaatctc cgtaagtaac atccctatcc agacaagcaa
    11461 gaacatcact cacttcatac cctgtcaacc aactggtcac ttggtgaact gactctgcct
    11521 ttccaccctt tcgctcaact tttgcaatca aggctaagta gacagcagca aatttcatat
    11581 tgtataattt ctgactcata cttctctctt tctatgtgta ctagtataaa taagaaaaag
    11641 aaggccgtca agccttcttt tgatttattc ttctgcttca tcttctgtaa attgactatt
    11701 gtacaagtca gcgtagaagc caccttgcgc catcagttcc tcatagttgc cttgctcgat
    11761 gatatttcca tctttcatga ccaagatcaa gtctgcattt cggatggttg acaagcggtg
    11821 ggcaatgaca aaggatgtgc gtccttccat caaacggtcc atggcttttt ggatcaattc
    11881 ctctgtccgt gtgtcaacag aagaagtcgc ctcatccaaa atcaaaagcg gtgcatcctt
    11941 aagaagggca cgagcaatag tcaatagttg tttttgtcct acagacaagg tcacggtgtc
    12001 atccaagatg gtatcatagc catctggcaa ggtcataata aagtggtgaa ttcccacagc
    12061 cttactagct tccatcattc gttcatcact aatccctatt tgattataga tgagattgtc
    12121 tcgaatagtt ccttcaaaga gccaggtatc ctgcaagacc attgaaaagg catcatgcac
    12181 ttctgaacgc gtcatagcct tggtatccac accatcaatg tgaatacttc ccttatcaat
    12241 ctcatagaat ttcatcaaaa gattgacaat ggttgtctta ccagtcccag tcggcccaac
    12301 aatggcaacc ttttgaccag catgaactgt cgcagagaag tcatagtctt gaacattgac
    12361 accgtccacc agaatttctc ctgctgacac gtcgtagaaa cgtggaatca gattgaccag
    12421 agttgattta ccagaacctg ttgacccaat aaaggccact gtttgaccag tttctgcttt
    12481 aaagctaaca tgttcaataa ctgcctccga atttgccgca tagcggaagg tcacatcctt
    12541 aaactcgacc tgacctttga agttttcatc agtcagctgc acttgaacag ggttttggat
    12601 agaagaatgc aaatctaaaa cttgattaat ccgcttagca gagaccatag tttggggaag
    12661 aacgatgaag agtgctccca tgagaaggaa gtccatgaca acctacatgg cataagacat
    12721 gaaaacaatc atgtcactaa agagaggcag acgcgctatc ggagcagcgt cgttaatcac
    12781 ataggcccca atccagtaaa tcgccacact caaaccactt gaaatcccca tcatgatagg
    12841 attcaaaata gccataagac ggttgacaaa caaatttaaa cgggtcaatt catcatttac
    12901 tgctgcaaat ttttcatttt gataatcctc tgcattgtag gcacgaacga cacgaatacc
    12961 tgttaaactc tcacgagtga tactgttcag tttatctgtc agcccctgaa tcaaggactg
    13021 ttttggaaag gctagcgtca tcaaaacggt cgtcatcagg acgttgacaa tcactgccac
    13081 aagtacggcc cagagccagt attctgaatg acctaaaatc ttcccaatag cccagatagc
    13141 cataattgga ccacacgtta ccacttgcaa gtccatagta atcaacattt gaacttgagt
    13201 aatgtcattg gtagtacgca tcaagaggct aggaattgaa aatttcttaa tctctgtctg
    13261 cgagtaatcc aaaactcggt taaaaatatc acttctcagc ctactagtat aagaagccgc
    13321 cactcgggat gcaaaaaatc caactgcaac tacggacaag aaggcaagaa agggcattcc
    13381 catcatcatg cttgccggct gccacaactc atctaaatta gttccttgac tacctagcaa
    13441 atccgtaatt ttcgagatat aggtcggcac ttccaactct agatagaccg aaaagcaagt
    13501 aaagagaatg gctagtaaaa tcatccccca ttcttttcta ctaattcttt tgactaattt
    13561 ctttattctc tcctcctatt cccttgatat ttgcctgtag ttgaccgaga actttctcaa
    13621 aaatcagtaa ttcatcttca tcaatgtctt ccatcaactg cttgtctatg cgttcaaaaa
    13681 aagccttaac ctgttgcatc tgagaacgtg ctttgtccgt cagacgaaca aacttagccc
    13741 gcttatcaac aggactcgcc tccaattcca ccaaaccatt ttgcactata cgcttaacca
    13801 gattactagc aacagacttg gtaatattga gttcctgctc gatatcttta atcaagacca
    13861 agtcttggtt tttctcgcga ttatccaaaa aatgcacaac ctgaccttgc ggcccaccca
    13921 taaattcaat gccgcaacgt ttggcttcct tttgcaccat caggtgaatt tgatgaccaa
    13981 aacgcttaaa gactaacatc ggtttatcca taatctcccc cttctaaata aaaatagttc
    14041 tctggagaat aattaaattt ctatgagaac tattttcttg attaaaaaaa tcccaagtga
    14101 ttttctcact taggatcatg ttctataggt taaattaaaa cccatctacg ttcgtataaa
    14161 tcttttggac gtcttcgtcg tcttcaagaa cgctgtaaag tttttcaaag gtttcaaggt
    14221 cttcgcctga caattccact tctgactgag gaatcatttc caattcagtc acttggaatt
    14281 cttcaatacc agactcacgg agggcaacga tagccttgtg aaggtcagtt ggcgctgtgt
    14341 aaactgtgat tgtaccttct tgtgcttcta cgtcatccac atccacatcc gcttcgagca
    14401 attgctcaaa gactgcgtcc gcatcttcac ctccaaatac aataacacct ttgttgtcaa
    14461 agaggtaaga aacagaacct gaagcgccca tgtttccgcc gtttttacca aaggctgcac
    14521 ggacattggc tgctgtacgg ttgacgttag aagtcaaagt atccacaatt agcatagagc
    14581 catttggccc aaaaccttcg taacgtcctt ctgtaaaggt ttcgtctgtg tttcctttgg
    14641 ctttatcaat cgctttatcg ataatgtgtt ttggcacttg ggcttgttta gcacggtcga
    14701 taacgaattt caaagctgag tttgattctg gatctggatc acctttttta gctgctacat
    14761 agatttctac accaaatttt gcatatactt tagagttggc tccatcttta gccgttttct
    14821 tggctacgat attggcccat ttacgtccca ttaggaatct ccttttttca cattttaatc
    14881 tttcttatta taacacaagt ttttttgatt ttcactagag gaaatggatt ttattagcaa
    14941 atcaagctag gatagcactt tacctgctaa gatggtcttg cctttctatc tttatcaaca
    15001 gacactcatc cacattcaaa aaacaaacta gaccattatc tgcaaataga aagtttcagc
    15061 caagtttgac aaagtcagct caaattactg tttgaagttt gtagatataa gcgacaaaaa
    15121 caatcatact gcaccttttg ttgacagtct actccagaca tatcatagtt caagtaaata
    15181 ctttgaaatc caacagttct tataggcgct attgtattct aagaaatcaa tagaagagtt
    15241 tctaagcaaa cctctaatac tcaataaaaa tcaaagagca aactagaaag ctagccgcag
    15301 gttgctcaaa acactgtttt gaggttgcgg atagggctga catggtttga agagattttc
    15361 gaagagtata atttacgtgt tcctaagatg gagaagttag actagtacac tggcacttct
    15421 aaaccattgc tagcaattga tttgttcata tttaatttca ttttttccat aaatgggtat
    15481 tagatataaa cagcaaaata tttccgatac gtgtcattct tgaatttcca atcatctaaa
    15541 acaagtaaag gataatcaat cccctgtata tcaaggaatt ggctaccctt tttacttttt
    15601 tacacatcct gtttgataga ctcattttaa catcacgagc atactccaat ggaaatcgct
    15661 aggcaagaga taaactttca gatattcgca gagagctcat cgcctctttt tgtcgcaaac
    15721 attcttctct cctaatcatt ttctacctta tcctctacct gaggatagag agttgttccc
    15781 caaatagaaa tcgtccgctt acgcactagt ggcaaatcgg ttttttcata aaccgtacgc
    15841 caccattccc aggcaagccc ggtacactct ctaattttga cagagagatt gcgaacattc
    15901 ccttttaaag gaatactagt ggtaaagtga gccgtcaaat cctgcccatt tctgtcccaa
    15961 gccttaggag tcaagacttc cttgccttga tgatcatagg ataattcatc ccaagtaata
    16021 taatattggg caacataggc accactatga tccagcagta aatctccgtt tctgtaagct
    16081 gtaaccttag tctcaacata gtctgtactg ttttgaaagg tcgcaactac attgtcacgt
    16141 aaaaaagaag ttgtatagga aatcggcaag cctggatgat cggctgtaaa gcgactgcct
    16201 tcttgaatca agtcctctac catatccacc ttgcctgtta caactcgggc acccgaactt
    16261 gggtcgcccc ctaaaataac cgccttcact tctgtattgt ccaaaatctg cttccactct
    16321 gtctgaggag ctactccttt tatcaaagat tcaaaagcag cctctacttc atcactctta
    16381 ctcgtggttt ccaacttgag atagacttgg cgcccataag caacactcga aatatagacc
    16441 aaaggacgct ctgcagaaat tcctctctgc cttaaatcct ctaccgttac agtatcttga
    16501 aacacatctc ctggattttt aacagcatct acgctgactg tataataaat ctgcttaaaa
    16561 ttaacaatct gaatctgctt ttcgcctgaa tggacagagt taaaatcaat atcaagagaa
    16621 ttccctatct tttcaaagtc agaaccaaac ttgaccttga gttgttccat gctgtgagcc
    16681 gtgatttttt catgctgcat tctagctggg acattattga cctgaccata atcttgatgc
    16741 cacttagcca acaaatcgtt taccgctccg cgaacacttg aattgctggg gtcttccact
    16801 tggagaaagc tatcgctact tgccaaacca ggcaaatcaa tactataagt catcggagca
    16861 cgatcgaccg caagaagagt gggattattc tctaacaagg tctcatccac tacgagaagt
    16921 gctccaggat agaggcgact gtcgttggta gctgttacag aaatatcact tgtatttgtc
    16981 gacaagctcc gcttctttct ttcgataaca acaaactcat cgggtagctg attaccctct
    17041 ttgatgaaac gattttcaat actttctccc tgatgggtca agagtttctt tttatcgtaa
    17101 ttcatagcta gtataaagtc atttactgct ttatttgcca tcttctacct cctaataagt
    17161 tcctggattg agttgcataa actcagactt gttcagcgaa atcagccgtg gttggactaa
    17221 gtaatccaaa atttcctcgt acaattcttc tgagacattg cgtcgccgtc tggctaaata
    17281 agaagtcgga atgaccgtat tatccaacat aaatacctta tctaagtcaa tcaaggttgg
    17341 tcttgtaaaa ggattacgag ctagatccgg ctcttctatc ataaagttct tgaccaaacg
    17401 tctggtcaag agagctggtt tgaaggtctg atttttaacc aactctttgt ttttagtcat
    17461 gctgttgtca atacagatat acatatgatt cttcacagcc aaatcgctac taatagtcgg
    17521 aaaaggcaaa taaagagcta caacatctcc tctcttaatc aagcaagagc accccctttt
    17581 ctcctaatgt aacatagaca ggattgacca agtcttctga ttgactcaga atttccaaag
    17641 tttgagtttg gcgcgctgtc aatttagtag catcttgtct cttcaataca aaatgcttgt
    17701 cgccaataac cttgacaata taatccttct ccaaagctga ctggtaaatc cacatcagat
    17761 gttgtctgtc ctgagaactc aagagagaag gattttcaag cctcccgata gtctgataaa
    17821 aatcaaaaac aggagctaac tcctgccaat ctgattggct agttgtcaag gctagaaaaa
    17881 gggctttgcg agctgatact tcttggttag ccttgagagt tactttcccc tccaagtttt
    17941 ttagaaatcg ggaaactcca gaaagcaaat ttttctctaa ctgcgagaaa taaaaacctt
    18001 tcgttcccag acataagtct ttcatgtcgc tttctctagc aaataagagc tcaaacattt
    18061 gatagtaaaa gaaaaatatc tggcactggg tcgcgctcat cttttcctta tcggcttctt
    18121 tttttaacca gagcaagggc gacaggtagc tggattgaga catttcctct acctcctact
    18181 cttttttaac tggagcatct gcactagctg ccacttcttt tgactggata ctttcccact
    18241 ggttaatctc ctctgagata agaccttcgc atgtcttgac aaatagggca aaagccttgg
    18301 tctttcctgc atatttctcc gtttggcatt gatagaggaa tttttctttc tccaggagtt
    18361 gcgcagtttt ttggtaagaa atccaatttt cctttgcatt atacaaattg ataatcccct
    18421 cacacagcaa gccgagactg gataaggcaa ccgaaatcaa acggtagcga tcacctggca
    18481 taggaatagc acaaaagaca gctatgagga aacctgccac gatttctgtt atttttaata
    18541 ccttatagcg cctacgatgt tgaacgcttt tctttaaaaa atgagctatc tgtacgtcta
    18601 atcgctctgt caggtacatt tcttctggcg tcatattcgt aactcctttc atttactttg
    18661 ataaccatag tataacatat ttgaatatca aagtatagta aaaactggac tataacttat
    18721 tagactccct gcgaaacaaa atatggtata gtagttctat gaattatgaa gcaagtaaac
    18781 aattaactga tacacgattt aagcgtcttg ttggtgttca gcgtaccact tttgaagaga
    18841 tgttagctgt attaaaaaca gcttatcaaa aaagtcggac aagctggtaa aatcttggct
    18901 gacagtggtt atcaagggct catgaagata tatcctcaag cacaaactcc acgtaaa
//
LOCUS       DAVBIC010000045        18943 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.045, whole genome shotgun sequence.
ACCESSION   DAVBIC010000045 DAVBIC010000000
VERSION     DAVBIC010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18943)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18943)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18943
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.045"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            complement(157..408)
                     /locus_tag="VQ664_001606"
     CDS             complement(157..408)
                     /locus_tag="VQ664_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789737.1"
                     /translation="MPKTKTLAELADVILWSFDFANDHAHAFFMDNVEWSHADSYFLS
                     FVSDDVEERYIENVYLDSLSVKQKFKFIFDFGDEWRFEC"
     gene            complement(698..2578)
                     /locus_tag="VQ664_001607"
     CDS             complement(698..2578)
                     /locus_tag="VQ664_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HET2789738.1"
                     /translation="MVRFTGLSPKQTQAIEVLKGHISLPDVEVAVTQSDQASISIQGE
                     EGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEVLALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIW
                     AELSYRNDLDGLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDIL
                     CPILDQHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIY
                     TT"
     gene            complement(2572..3441)
                     /locus_tag="VQ664_001608"
     CDS             complement(2572..3441)
                     /locus_tag="VQ664_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET2789739.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILDKTSISTPENLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWYEALSSYQLPVHLENDAN
                     CVGLSELLAHPDLENAACVVIGTGIGGAMIINGRLHRGRHGLGGEFGYMTTLAPAEKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNILCQEAIERMNRNLAQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQDVKKAVDNFVDTYEEYTVAPVIQACTYHADANLY
                     GALVNWLQEEKQW"
     gene            complement(3525..6170)
                     /locus_tag="VQ664_001609"
     CDS             complement(3525..6170)
                     /locus_tag="VQ664_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HET2789740.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQV
                     LEDERFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGRPVEATIEDLGANFEYDLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGKQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGHEVLENTDRYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELIVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFALECHQAQERFSAFRRAKALQTPFTSLQLARQEGS
                     VVATGSLLSHSVLSIPQVCPTAFKVAENEEGYVFRYYNMSQENVHISEHQQTILDLLE
                     RPYPVHSGPLDPQEIRTEFIKKEEI"
     gene            complement(6261..7541)
                     /locus_tag="VQ664_001610"
     CDS             complement(6261..7541)
                     /locus_tag="VQ664_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HET2789741.1"
                     /translation="MIYSKEIVREWLDEVAERAKDHPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDALLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEENWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETSQFDETF
                     VAATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFAALNLADSQSVIADAKRLQDEIQEGIENYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSIDDEVYQATRRTILSSEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKKFLLDQLVACDGGTGVMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            7712..9796
                     /locus_tag="VQ664_001611"
     CDS             7712..9796
                     /locus_tag="VQ664_001611"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HET2789742.1"
                     /translation="MKPLLETIDTRFGTASKHAFSRGNTLPYTGVPFGMNYFVPQTSD
                     QDGSWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTSQLGGDSLFHRQSSYDIDK
                     ACFQPHYLKLFSLRYQIETQLTPTCYGASIRLNQKQGKALSLYLHAADELTVEQVDKR
                     TLALRQEGKTETNKNSLTMFTALQMNTDILAISQEAGDWRIDLASSQTEMQLATSFIS
                     PSQALINLPQEDFDSCKTSAQADWENLLHRFDIIETGEADRTFFDHCLYRLFLFPQTF
                     YEVDESGKAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMAPDLEGELFQAMLETASKADP
                     LGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIASCAKKLENIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGIPLFDHLRVYLAKENKWLDIHTEQNHSHFNFVKECRLDKTLVSTIQHQDLLKAE
                     QLTFTLSWLPNH"
     gene            complement(9836..11515)
                     /locus_tag="VQ664_001612"
     CDS             complement(9836..11515)
                     /locus_tag="VQ664_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HET2789743.1"
                     /translation="MKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQE
                     DPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGK
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYG
                     NAGKFAEVWMDGARGEGAQKVNYEFEKWFETIRDLQGDCLIFSTEGTSIRWIGNERGY
                     AGDPLWQKVNLDKLGTEAELNYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVS
                     GPALSADFDCRHLTDGLETSSWASDADLPIQLELDLGSPKTFDVIELREDLKLGQRIA
                     AFHVQVEVDGVWQEFGRGFTVGHKRLLRGPLVEAQKVRVMITEAQSIPVLTKISLYKT
                     PGLSKKEVVQELAFAEKSLAVAKGETLHFRIERSESSSSLEAKISIQPGTGVHGVAYQ
                     DEIYVLAFQAGETEKRLTLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS"
     gene            12270..13499
                     /gene="arcA"
                     /locus_tag="VQ664_001613"
     CDS             12270..13499
                     /gene="arcA"
                     /locus_tag="VQ664_001613"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HET2789744.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESDYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIE
                     GGDELILSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGNLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            13557..14573
                     /gene="argF"
                     /locus_tag="VQ664_001614"
     CDS             13557..14573
                     /gene="argF"
                     /locus_tag="VQ664_001614"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HET2789745.1"
                     /translation="MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHY
                     LAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLV
                     YCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITED
                     ADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPA
                     FHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLY
                     IPKV"
     gene            14738..15685
                     /gene="arcC"
                     /locus_tag="VQ664_001615"
     CDS             14738..15685
                     /gene="arcC"
                     /locus_tag="VQ664_001615"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HET2789746.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVIVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNNGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVDADLFIVLTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            15894..17405
                     /locus_tag="VQ664_001616"
     CDS             15894..17405
                     /locus_tag="VQ664_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HET2789747.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYEA
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNTWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            17427..18758
                     /locus_tag="VQ664_001617"
     CDS             17427..18758
                     /locus_tag="VQ664_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HET2789748.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICRDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEETLWRCMARY
                     NTIEEQASMGFAPDSSFPLTYAEKGLLQVKLHGPGSDQLELEVGGAFNVVPDKANYQG
                     PLYEQVCNGLKEAGYDYQSTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEIRIDIRTPVLADKE
                     ELVELLTRCAQNYQLRYEEFDYLAPLYVAEDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
     gene            18853..>18943
                     /locus_tag="VQ664_001618"
     CDS             18853..>18943
                     /locus_tag="VQ664_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2789749.1"
                     /translation="MKLSYEDKVQIYELRKQGQSFKQLSKRFGV"
BASE COUNT         5322 a         4291 c         3910 g         5420 t
ORIGIN      
        1 aggaagtcta ttgaaatact aagcctacac agactgattt caattttacc attcttcata
       61 gtcaaaacca tcataatctg gatattgttc tggcaacgtt ccaaccgaac gtacgagata
      121 agcttcttcg tcctctgtct cgatttctct cagcacttag cattcaaaac gccattcatc
      181 accgaagtcg aaaataaact taaatttttg tttgacactt aggctatcca gatagacatt
      241 ttctatgtaa cgttcttcaa catcgtcact aacaaagcta agaaagtaag aatctgcatg
      301 actccactca acattatcca tgaaaaatgc atgagcatga tcatttgcaa aatcgaaact
      361 ccataaaatc acatctgcta gttccgctaa cgtttttgtt tttggaatct atatatgtcg
      421 gtagcaacct tttttaattt gacggaaatg atccaagctt ctacagatgc tggcttttca
      481 gcttctattt cttgttttac taattttaac tgtagcattt gaaaccagat aattcttctg
      541 tttcacgcga aacaccctgc gccaagcaag gtgttcttgt ttttatactc aatgaaaatc
      601 aaagagcaaa ctaggaagct agctgcaggc tgctcaaaac actgttttga ggttgtagat
      661 ggaagctgac gtggtttgaa gagattttcg aagagtatta agtcgtataa atcgtcgaag
      721 ctgtcgcaat ggtatgccac tggttagctg tagttgctgc gaaatccttg tctgcgtaga
      781 agtcagtaaa tggtaggatt tcaacttcca gctcgtcgat gcggtcaagc tggccagcca
      841 gataaacctc gatacggctt tctgctcgtt tgatgcgttg caagagtccg cccatacgga
      901 tgtcaactgt atccaaacca aagaccttgt tttctttcag ccattggtga ctaaagaggg
      961 catggaagtc ttcaatttgg cttctaagtt ctggtaattc ttgtctggcg atttgttgta
     1021 aactttcttt atcatccgct tggtaggcct gacgaatgcg tcgtcccaca tctactttgc
     1081 tacttaaaat agcattcaac tgggcctgag tttcaaagag ataagcatag tttccagctt
     1141 tttctttaat gttagcaagc gtctcagcag cctgagcgaa gtgcggtttg tcctgttcag
     1201 gtgtcatgtg ttgatcaaga atcggacaaa gaatatcctg ataaaaaaca tagcggttgg
     1261 gattgatacc gctgagattg cctggtaggt ctggtaagag gttggcaagg tcaatctgca
     1321 taaaatcctc aaccgttaga ccagtattgg tcttgaagtg cgcagacaaa ccatctaggt
     1381 cattgcgata gctgagttct gcccagattt gcaagcttgg taggatagag aactgggcag
     1441 tttcaccacc attgtctccc caacccgtta cgatgacttc tttaatctga ttggcacggc
     1501 aggctttatt agcctcgata gccactagac ggctaaaatg gttgtgaggt gtaaagccaa
     1561 tccacttcca agctccccct gcaaatgcaa ggtcatggct aatcttgtga tgattgcgga
     1621 aattacggtt gtatttttcc tcgctatcct gataataatc ccagtaaacc agagtcacac
     1681 ggtctttgag acggtctagg tagacacgag tttcctctgg aatttccaca tcacggtcgt
     1741 actggccatc cgctgacatg agtttgaaga acatatcact ccacatctgg cagtggaaac
     1801 catatttgtc agcaatatcc agcacgcgct ccaagtgttg gcacatgagg agactacgat
     1861 ccacaacacc gttcaaaatc aggtagcgtc ccaaaccaac caagtgggct tcgtccatcc
     1921 cgatattgac cttgcgagtc ttcagtttag acaacgtggc aaacatgcca tcaatcaggt
     1981 cataaacctt ttcttcgcca atgagaagaa tgtcctctac atcacggagc tcctgcactt
     2041 ccttgacacc ccatttgaca aaggccgaca agtgggccaa ggtctggatg catggtacaa
     2101 aggtcatgtc aaactgttga gcataggctt cgatttcctg caactcctct gctgaataag
     2161 ctccacggaa atagccaaag taaggctgcc cttcaatctg gtaagtgtct tccatgtaaa
     2221 gttcaaaggt tgagtagccc atgagagcca agacctcaat catctgcttg gcagaagcca
     2281 cattcagcac cgcatttcga gaacagtcaa ccatgtaagc caaatcttcg taagctgctt
     2341 gttcctcaat ctctacttta tcagcttctg ctagaactgt taccaacaag gataaggcac
     2401 gataaagttg gtgaggtttg cggtaggtca attgatagtg accttcctca ccctggatag
     2461 agatagaggc ttggtcagac tgagtgacag ccacttccac atctggtaga gaaatatgac
     2521 cttttaaaac ctcaatagct tgcgtttgtt tgggactaag tcctgtaaat cttaccattg
     2581 cttttcctcc tgtagccagt tgacaagagc accgtagaga ttggcatctg cgtgataggt
     2641 gcaggcctgg ataactggtg cgaccgtgta ttcttcgtag gtatcgacaa agttatcaac
     2701 agccttcttg acatcttgga taaaatctgg attttgactg atagagccac ccagactgat
     2761 gacatctgga tcgatcagat actggatatt gagcaagcct tgcgccagat tgcggttcat
     2821 gcgctcaatg gcttcttgac aaaggatatt accagctgcg gcctcttggt aaatcttgcg
     2881 accgtcccaa tcagtatgac cagatttttc aatcacgtat cgtaccatat tcccagttga
     2941 tgctagttgc gaccagttat taagtttttc agcaggggca agggttgtca tgtagccaaa
     3001 ttctccaccc aagccgtggc gacctcgatg aagtctacca ttgataatca tggctccgcc
     3061 aatccctgtc ccaatcacga cacaggctgc attttcaaga tctggatgag ctagtagttc
     3121 actgagtcca acgcagttgg catcattttc taaatggaca ggtagctgat aagagctaag
     3181 cgcctcatac caagaaaagc catggatgta gggcaccgca ctgaagccat caatcacacc
     3241 tgtctcttga ttgactgcac ctggaacgct catagcaatc ccactgtaat cctgttctga
     3301 caagcgttga tctagccacg ctagtaaatc ctccaagttt tcaggcgttg aaatacttgt
     3361 cttatccagt attttcccat caggagtcag actggcaaac ttaatcccag tccctccgat
     3421 atcaatcgtt gcaatggtca ttgtttttac cataaaaagg ggcgaatcag cagttagttc
     3481 ttactttttc gcccctcctt tcttttgatg tttacttttt gaaattaaat ttcttctttt
     3541 ttgatgaatt ctgtacgaat ctcttgtgga tccaatggtc ctgaatgaac tggatatggt
     3601 cgctcaagta agtcaagaat ggtttgttga tgttctgata tgtgcacatt ttcttgactc
     3661 atattatagt aacggaagac atagccttct tcattttccg ccactttaaa ggctgttgga
     3721 caaacttgcg gtatgctgag aacagaatgg ctcaagaggc taccagtcgc aaccacgctt
     3781 ccttcctgtc tagcaagctg aaggctggta aacggtgtct gcaaggcttt ggcacgacgg
     3841 aaagctgaaa agcgttcttg ggcttggtgg cattcaagtg caaactcgac ttcaaactca
     3901 cgcaagcatt gtgcttctgg cgttgggaag tagccccagt cacctagctc acctgatgca
     3961 cgcaaaatgg tcacggcaat ggtgttatcc ccaaggattt cgtattcatt caatccctta
     4021 ttggatacag tcaccccttt ttcatcgtca tacagactga caaaagcttg ttggtgttga
     4081 ggattttcag gattttccca tgaagcagct ggtttgtttg gtcgtgtcac cacctcatag
     4141 atactttcag aatcattgct tggacgcgtg ttatgagtct tgaccaagag acggatacgg
     4201 tgatccttgg cagtgttagt aaagcgagtc ttgaagcgga tttgtggatt gtcaacaaag
     4261 acaatcaact cagtttccag aggaatgttt gtcaattctt ctgaccgtcc agcctcacgc
     4321 ttcataaact cgatgatacc ttgttgctct tcttctagct tttcatccgc actgacaggc
     4381 acggtcaatt catgtttgag caagatttta gcatagcgat ctgtgttttc caagacctcg
     4441 tggcccttaa gctctgcaaa gattggctct gttccttttg gttggaaata gatatactcg
     4501 tttccgatgt ccccacggtc ttcgaagcgg ataaagtctt cataggcttc gtgagttgtc
     4561 ttgtcatata ctgtgatatt gtcatccaca ctcaccgtta cgaatggtgt atcaatcact
     4621 ccgttttggt aaataccctc acggtgttct tgttttcctt ccagcaattg gaaggttgtc
     4681 caagaaagcg gcgctaggtg aactggaatg gtcacgcgca cttgtcgagc aatacgagct
     4741 tggcggaact tgtcttttgg taaatcgtac tcaaaattag ctccgaggtc ttcgattgta
     4801 gcctctacag gacgaccatc caagtcctcc acacggtaac ttggtaagat aagagcagcc
     4861 atctttttgt agccttctgt tgggtgcaat tccttgaaat cacaagtcgc cacatcaatc
     4921 actgtgctga cagtatcgac cttatcatgc aagcctgtgt taatgacagt aaagagatag
     4981 tcactttgag ccttatccgt agcaatttta cccttccact cgttgagcaa gttactttta
     5041 acaaagtttc ctacttggtt gaccttggca aaacgcgttt ccatctcgcg gtgaacttcg
     5101 tccacgctac agccacagat actatcatgt ggcgcattct gcaaaagtgt tttccaagca
     5161 taggtcaact ggtccttgtg gttgtgtcca ccagtgataa tagtcaaggg ttctaccact
     5221 tgctctagga ggttgctatt ttcttggaag gcttgtttta ggtaaatgcg ggatgaagaa
     5281 gtgttggcaa gtgtgtacca gccatctgtt tcctgactgg tcaactcgcc tgtaacagtt
     5341 gataagtgtt caggaagcgc accttctaca gcttgaacat attcatcaaa agaactatga
     5401 acaaagatta catccgggaa gagttcattt gccacacgaa tggcttcgct cagatttttc
     5461 tgtacaggct ggtggtcaca gccgttcatc atcaaccatt ggttggtcga agcgtaggca
     5521 cgcacatctg acaatttttg tttccagaag gtcaaggcct catctttgtc aactgggatt
     5581 tcattcccat tactgtacca gttggcaaag agaataccta aaacacgact accatccaca
     5641 ccctgccagt acatttctga aaactgggat gtaaaccgct catcttcaag gacttggttg
     5701 tcaaatccaa tcggcttcac accacgacca aaggctgcca cgtgaatacc tgatttttga
     5761 aggatttgag gagcttgtcc catatttcca aaggtatctg gaaagtagcc aatctgggtt
     5821 gatttacccc atttggcagc ttcttgttga ccaatcaagg tattgcggac attggcttca
     5881 ctggagatca agtagtcatc ctgcaagatg taaaagggac caattttaag tttgccctcg
     5941 tcaatgtagc gttggacctt gtcgcgattt tcagggcgaa tttgtaagta gtcatcaagg
     6001 acaatagttt gtccatccaa gtggaaactc ttgaactcag ggtcattttc aaagagatca
     6061 aagagattgt caaacaattc caccaactgc atacgatggc tttcaaaagg caagtaccac
     6121 tcacgatccc agtgactatg tgagataata tgtacaacaa cattttccat gaagtaaaac
     6181 ctcattctaa atttaaattt taacgtttta aatgtaaact tgtgattctg ataagaatcg
     6241 gttgagctaa agcgagcccc ttagcggata tccaagtaat ccaagaccaa ctcacagaac
     6301 atcatgttag cccaggagaa ccattcacga gagtagaggg tcggatcatc tacgtggaag
     6361 ctttcgtgca tgacacctgt accaccatcg caggcaacca gctgatccag caagaatttt
     6421 ttctctgcct tatctcttgt tgtcaatcct tggatagaaa gggcgattgg ccagatatag
     6481 cgatagaagg tatgagaact tccgagaccg ctagcgtatt ctccttggta gaagtatgga
     6541 ttttcagagc tcagaatggt acggcgagtg gcttgataca cttcatcatc gatcgaacag
     6601 tagcccagat agggcgcagc tagtagactt ggtacatttg gatcatccat gatgctggca
     6661 tttcctaggc catctacttc aaaagcgtaa atcttttcgc ccttgctgtt ggtggtgtaa
     6721 gcgtagtttt cgattccttc ttggatttca tcctgaagac gcttggcatc agcaataaca
     6781 ctctggctat cagctaggtt taatgctgcg aagatttctt gcacataacc caagactact
     6841 acagcaaaca tatttgacgg aatcaagtaa ctatactggc aacagtcatc actcggacga
     6901 aaagctgacc aagtcatacc tgtcactgca aagtcaggtc caaagccatc atttaccaag
     6961 gtgtcttcct tacggtccgt atctcggaca aaacgataag gagagttctt gtggtcttgt
     7021 tcaactgtcc atagatggag aatttcctta gtcgctgcga caaaagtttc atcaaactga
     7081 ctagtctcgc cagtctcttt ccagaggaga taagccaact gcaaaggata gcaaagcgaa
     7141 tccacctcat acttgcgctc ccagatccag ccgttaaggt ctgtgtggtc agtctcgtgg
     7201 tgccctttcc agttctcctc aatgttgaag gagttagcat agggatcctt gagtaccaag
     7261 gtcatctgac gtttgaccaa acctgcaatg gtctgacgca ggagggcatc tcttttagct
     7321 acatgaaggt agggtctgag ttgggctgtc gaatctcgaa gccacatggc aggaatatcc
     7381 ccagtcaaga caaaagttga accatcttct aagatttcaa ccgtattgtc caaggtatcg
     7441 gtgtagcaac gctcaaagac atcaacccac tctggatggt ccttggcccg ctctgctact
     7501 tcatctagcc attctctaac aatttctttc gaataaatca tcgtgcaatt ccctctttca
     7561 aacaagtttc atgttcagta tatagctttt gagacagaaa atacatacac aaatgatagt
     7621 catttttcta caaaatagtt atctttaaaa ctccttttct aaaggccctc tttttctgat
     7681 ataatgtaga aaaacagcta aaggaaagac tatgaaacca ctacttgaaa ccatcgatac
     7741 ccgctttggt actgctagca agcatgcctt ctctcgggga aataccctgc catacacagg
     7801 cgtgcctttt gggatgaatt actttgtgcc ccagaccagt gaccaggatg gatcttggtt
     7861 ttttgatccg catctgccta tctttcaggg gattcgatta actcaccagc ccagtccttg
     7921 gattggggac tactcttggc tccttctgac acctgtcacc agtcaactgg ggggagacag
     7981 cctctttcac cgccagtctt cttatgatat agataaagct tgcttccagc ctcactattt
     8041 gaagctcttt tctctgcgtt atcagattga aacccagctc acaccgactt gctatggtgc
     8101 ttctattcgt ttgaatcaaa agcaaggcaa agccctctcc ctctatcttc acgcagcaga
     8161 tgaactgaca gtagagcaag tagataagcg gactcttgcc ctgcgacaag aaggtaaaac
     8221 tgaaactaac aaaaattcgc taacgatgtt cactgccctg caaatgaaca cggatattct
     8281 tgctatcagc caagaagctg gggactggcg aattgactta gcaagtagtc aaaccgagat
     8341 gcaactagcc acttctttca tctctccttc tcaagctcta atcaatctac ctcaagaaga
     8401 ttttgatagc tgtaaaacaa gtgcccaagc ggattgggaa aatctcctcc atcgttttga
     8461 cattatagag acaggagagg ctgaccgaac cttctttgac cactgcctct acagactctt
     8521 cctcttccca cagacttttt atgaggttga tgagtcaggg aaagccatcc acatggatct
     8581 ggctactggt actgtcaagc ctggtgtcct ctttagcaac aatggtttct gggatacctt
     8641 ccgcaccacc ttccccctct ttgcccttat cataccggag cactatcaac gctttttaga
     8701 aggtttcctc aatagctacc gcgatactgg tttccttcca aaatggctgg ctccagatga
     8761 acggggtatg atgccaggta cactgctaga tggcattatc gcagatagcg cctgtaagga
     8821 catggccccc gacctagaag gagaactctt ccaagccatg ctcgaaacag ccagcaaagc
     8881 cgaccctctc ggcatcaatg gccgccacgg actagcccaa taccaagaac taggttacct
     8941 ctctaccgac caccacgaaa gtgttagcca tactctagac tatgcctata gtgacttttg
     9001 tatcgccagc tgtgccaaaa aactagagaa catagaaatc gctgaaacct acaaggctgc
     9061 ttcacaaaat taccgccagc tatttgacgc tgagacaggt tacatgcgag cacgagacaa
     9121 tcaaggaaac tttcaccctg acttctctcc ttatagttgg gggcgagact acgctgaatg
     9181 ctctgccatt caagctactt taggcgttct ccacgacatc cctggcttaa tccaactgat
     9241 gggtggaaaa gaaaccttta gcaactatct tttgaaagcc tgtcaagatg ctcccctctt
     9301 tgaaacaaca ggctatggtt acgaaattca cgaaatgagc gagatggcta ctgctccttt
     9361 tggacaaata gccatttcca accagcctag tttccacatt ccttatctct tccgctacag
     9421 cgattaccct gactacactg cccttcttat caagacgctc cgtcagaaag cttttcaccc
     9481 aagttgggaa gcctatcctg gagatgaaga caatggtagt ctctctgctt ggtacatctg
     9541 gtcagctctc ggattttatc caacctgtcc aggaaaacca agctatgatc tcggaatccc
     9601 tctctttgac catctacgag tctacctagc taaagaaaat aaatggctag atattcatac
     9661 tgagcaaaac cacagccatt ttaactttgt caaagaatgc cgactggaca aaacactcgt
     9721 atcaactatt caacaccaag acctcctaaa agctgaacaa ctaactttca ccctcagctg
     9781 gctaccaaat cactaataac caaaagaacc tttgcatcgc gcaaaggttc ttcttttatg
     9841 aaacttggac ttgaagttga tccacaagct gaccatccac cgttaggttc agatagaaat
     9901 ccaaggtttt atctcctgcg aaatacaagg ttggtagcgt cagccttttt tcagtctcac
     9961 cagcttgaaa cgcaaggaca taaatctcgt cctgataggc gacaccatgg acacctgtcc
    10021 ccggttgaat cgaaatctta gcctctaaag aggagctact ttcactacgt tcaatcctaa
    10081 aatgaagagt ctctcccttt gccacagcta ggcttttttc tgcaaatgct agttcctgaa
    10141 caacttcttt ttttgataac ccaggagttt tataaaggga aatcttggtc aatacaggga
    10201 tagattgtgc ctcggtaatc atcacgcgca ccttttgtgc ctctactagc ggacctcgca
    10261 agaggcgctt atgaccaact gtgaagcccc tgccaaactc ctgccagaca ccatccacct
    10321 ctacttgcac atgaaaagca gcgattcgtt gccctagctt caaatcttct cttaactcaa
    10381 ttacatcaaa agttttagga gaacctaaat cgagttctaa ctggatgggc aagtctgcat
    10441 cgcttgccca agagctggtc tcaaggccgt ctgtcaaatg gcgacaatca aagtctgcgg
    10501 aaagagctgg accagatacc tcagctccca gagccaaatc ttctttatag agctcattgc
    10561 gataggtcgc aaattcataa agtcgttcaa tatcctttgc atcaaagagc ccagcttgat
    10621 tcggcggaat attaagcaag agtggagttc ctcgccctac tgagtgaaag tagatttcga
    10681 ccaactcctc gagagactta ggatcctgat cctcatggta gaaccagcct ggacggatgg
    10741 aaacatctgc ctctccgatt gaaaaaatcg tgcccgaggg atccccgtgc tgaagatagt
    10801 tcagctctgc ttctgttcct agtttatcaa gattcacctt ttgccacagt ggatcacctg
    10861 cataccctcg ttcattgcca atccagcgga tactggtgcc ttctgttgaa aaaatcaagc
    10921 aatcgccctg caggtcacga atggtttcaa accatttttc aaattcataa ttaacctttt
    10981 gcgcgccctc tcctctggca ccatccatcc aaacctcagc gaacttacca gcattcccat
    11041 agttaggatt tgataagatt tccttcaact gagccagata ataggcattg tagtccgctt
    11101 ctcggtccac atgatagagg ggactatggg catcccacgg tgacaggtag acccccatat
    11161 ccatatcaaa ctctgtggca gcttgggata cttcaaggag caagtcgccc tttcctctcc
    11221 tccaaggact gaccttaacc gaataatctg tgtgagctgt cggataaagg acaaagccat
    11281 cgtggtgctt gaccaccaaa atcaactttt tgaagcccgt ttccttgagc acacgaaccc
    11341 actcacgcgc atccaactga ctcgggttaa agcgctcagg atcctcctgt ccagtccccc
    11401 attcttggtc ataaaaggta ttaggaccga agtggataaa agctgctagt tcatctccca
    11461 gataagctag ctgagtctga cttggtaacg gtccatgcgg tttgattttc ttcatcgtta
    11521 tatatctcct tcttttgcaa cttctcttgt tcacaaggtt atccacaggt tgtggataat
    11581 aaaccatgat ctaacagcca gctctttcca actccaactg gtaggctcag gatttttctc
    11641 ctcaatgttc cctcttcaaa cagctctgtc atatggttct gctaacacct ctcagaatgc
    11701 tactctccat aattattctc aggcttcttt caggtcattg tgtgaagacc attcactctc
    11761 cagacttttc cacagattgt gaataagtga ttattctaag ctatcacctc gtcgactata
    11821 acaaaaaata aaaagagggt caataagata attatctctt cctaaatact cagaaaagat
    11881 tctataattt gtacaattga acaagaaatg cttctccaaa atctatcttc aaaagaatgt
    11941 tgcatctttt tatcctttca cacaaacatt tctctttata cagatccaag tgataaccag
    12001 atgataattg gacacttttt ggtcatttgt atattttttg aaaaattttt taaaaaaatt
    12061 ttatatcctt tttatagaag tttatgcatt tgtatctatg tattctatcc tatgttatgt
    12121 ataataacat aaaattgtgc taaacatcat aatttatatt attttccgag aaattatagc
    12181 cattgacatt acctaggaat tgcgttataa catacatgta agcggtaccc aaaatggtgc
    12241 caagtcaaaa tttttaagga ggaaaataca tgtcttctca tccaattcag gtcttctcag
    12301 aaattgggaa actgaaaaaa gttatgttgc accgtccagg caaggagtta gaaaacttgt
    12361 tgccggacta tcttgaaagg cttctttttg atgatattcc tttcttggaa gatgctcaaa
    12421 aagaacatga tgcatttgcc caagctcttc gcgatgaagg aattgaggtt ctctacctag
    12481 aacaactcgc tgctgaatca ttgacctctc cagaaatccg cgatcaattt atcgaggaat
    12541 acttagacga agccaacatc cgtgatcgtc aaaccaaggt tgctattcgt gaattacttc
    12601 acggcatcaa ggacaaccaa gaattggttg aaaaaacaat ggctgggatt caaaaagttg
    12661 aattgccaga aattcctgac gaagctaaag atctaactga cttagttgaa tcagattatc
    12721 catttgcaat tgacccgatg ccaaacctct atttcactcg cgacccattt gcaacaattg
    12781 gaaacgccgt atcgcttaac cacatgtttg cagatactcg taaccgtgaa acactctacg
    12841 gtaagtatat cttcaaatac cacccaatct atggcggaaa agtggatttg gtctacaacc
    12901 gtgaagaaga tacgcgtatc gaaggtggag acgagctaat tctttctaaa gacgtccttg
    12961 cagtaggtat ctctcaacgt acagacgcag cttctatcga aaaacttttg gtcaacatct
    13021 tcaagaaaaa tgttggcttc aagaaagttt tggcctttga atttgctaac aaccgtaaat
    13081 tcatgcactt ggatactgtc ttcactatgg tagactatga caagttcact attcacccag
    13141 aaatcgaagg caaccttcac gtttactcag ttacttacga aaacgaaaaa cttaaaattg
    13201 ttgaagagaa aggtgactta gctgaacttc ttgctcaaaa ccttggtgta gaaaaagttc
    13261 atttgattcg ttgcggtggt ggcaatatcg tagcagctgc gcgtgaacaa tggaacgacg
    13321 gttctaacac tttgaccatc gcacctggtg tggtagttgt ttatgaccgc aataccgtga
    13381 ccaataagat tttggaagaa tacgggcttc gcttgattaa gattcgcgga agtgaattgg
    13441 ttcggggccg tggtggacct cgttgtatgt ctatgccatt tgaacgtgaa gaagtgtaat
    13501 cgctgttcgg tattcgtcaa tagaaaatgt aaaaaataga aagaggaaat aataaaatga
    13561 caaattcagt attccaagga cgcagcttct tagcagaaaa agactttacc cgtgcagagt
    13621 tagaatacct tattggtctt tcagctcact tgaaagattt gaaaaaacgc aatattcaac
    13681 accactacct tgctggcaag aatatcgctc tcctatttga aaaaacatct actcgtactc
    13741 gtgcagcctt tacaactgcg gctatcgacc ttggtgctca cccagaatac ctcggagcaa
    13801 atgatattca gttgggtaaa aaagaatcta ctgaagatac tgctaaagta ttgggacgta
    13861 tgtttgacgg gattgaattc cgcggattca gccaacgtat ggttgaagaa ttggcagaat
    13921 tctcaggcgt tccagtatgg aacggtctaa ctgacgaatg gcacccaact caaatgctcg
    13981 ctgactactt gactgttcaa gaaaacttcg gtcgcttgga aggcttgaca ttggtatact
    14041 gtggtgatgg acgtaacaac gttgccaaca gcttgctcgt aacaggtgct atccttggtg
    14101 tcaatgttca catcttctca ccaaaagaac tcttcccaga aaaagaaatc gttgaattgg
    14161 cagaaggatt tgctaaagaa agtggcgcac atgttctcat cactgaagat gctgatgaag
    14221 cagttaaaga tgcagacgtt ctttacacag acgtttgggt atcaatgggt gaagaagaca
    14281 aattcgcaga acgtgtagct cttcttaaac cttaccaagt caatatggac ttagttaaaa
    14341 aagcaggcaa tgaaaacttg atcttcctac actgcttgcc agcattccac gatactcaca
    14401 ctgtttatgg taaagacgtt gctgaaaaat ttggtgtaga agaaatggaa gtaacagacg
    14461 aagtcttccg cagcaagtac gctcgccact tcgatcaagc agaaaaccgt atgcacacta
    14521 tcaaagctgt tatggctgct acacttggta acctttatat tcctaaagta taattttaga
    14581 taataaaccg tctaccaaca gctatgaggg ctgcgactaa tagctttagt ccggtcctct
    14641 tttatgtaat ggtaatctat tatttcttat aaaatatgtg aaaaatcatt aaattgaaat
    14701 ctaaacgcat tctattgagt gtgataaagg agaatttatg gcaaatcgta aaattgtagt
    14761 agctttggga ggaaatgcga ttctttcttc tgacccatca gcaaaggctc aacaagaagc
    14821 tttagttgaa acagctaagc atcttgtaaa attgattaaa aatggagatg atttgattat
    14881 cactcacggt aatggacctc aagttgggaa tctcttgctc caacatttgg catcagactc
    14941 tgaaaagaac cctgccttcc cactcgactc acttgtcgct atgacagaag gtagcatcgg
    15001 tttctggttg aaaaatgctt tgcaaaatgc tctcttggat gaaggcatcg aaaaaaatgt
    15061 tgcctctgtt gtaacgcaag ttatcgtaga taaaaatgat ccagcttttg ttaacttgag
    15121 taaaccaatc ggtcctttct attcagaaga agaagcaaaa gcagaagccg aaaagagcgg
    15181 agcgactttc aaggaagatg ctggccgtgg ctggcgtaag gtcgttgcct caccaaaacc
    15241 tgttgacatc aaagaaattg aaaccatccg tactctttta aataatggtc aagtcgtcgt
    15301 agctgcaggt ggtggcggta ttcccgtcgt caaagaaaac aatggacatt tgactggtgt
    15361 cgaagcggtt attgataaag acttcgcttc ccaacgtttg gcagaattgg ttgatgcaga
    15421 cctcttcatc gttttgacag gtgtagatta tgtatttgtt aactacaaca agccaaacca
    15481 ggaaaaattg gaacatgtga atgttgccca gctggaagaa tatatcaaac aagatcagtt
    15541 tgcaccaggt agcatgcttc caaaagtaga agcagctatc gcttttgtca atggtcgtcc
    15601 agaaggaaaa gcagttatta cttcccttga aaatctaggc gccttgattg aatctgaaag
    15661 cggaacaatt attgaaaaag gataagttgt tttactaata agatgtattc tatttctagt
    15721 atctttatat caaattagaa attattcttg aaaacatgta caatatttca aaagatacta
    15781 gttttagact ttaatatggt aaaacaaata taaatagaaa gcgttttctt gaatgtttat
    15841 ttaagaaagt agttggtttt ttacactttg ttagacatca ggaggaaaaa caaatgagtg
    15901 aaaaagctaa aaaagggttt aagatgcctt catcttacac cgtattattg ataatcattg
    15961 ctattatggc cgtgctaact tggtttatcc ctgcgggggc ctttatagaa ggtatttacg
    16021 aggctcagcc tcaaaatcca caagggattt gggatgtcct catggcaccg attcgggcta
    16081 tgctaggtac tcatccagag gaaggttcgc tcattaaaga aacgagcgca gcgattgatg
    16141 tagccttctt catccttatg gttggtggtt tccttggcat tgtcaacaaa actggtgctc
    16201 ttgacgtagg gattgcctct atcgtgaaga agtataaggg ccgcgaaaaa atgttaattt
    16261 tggtattgat gcctttgttt gccctcggtg gtacaactta tggtatgggt gaagaaacaa
    16321 tggccttcta tccactcctt gtgccagtta tgatggccgt tggttttgat agcctgactg
    16381 gtgttgcaat tattttgctc ggttctcaaa tcggctgttt ggcatctact ctgaatccat
    16441 ttgcgacagg tattgcttca gcgactgcgg gagttggtac aggggacggt atcgtacttc
    16501 gtctgatctt ctgggttacc ttgactgctc ttagtacttg gtttgtttac cgttatgcgg
    16561 ataagattca aaaagatccg actaagtcac tggtttatag tactcgcaaa gaagatttga
    16621 aacactttaa cgtagaagaa tcttcatctg tagaatctac acttagcagc aaacaaaaat
    16681 cagttctctt cttatttgtg ttgacattca tcttgatggt attgagcttc attccatgga
    16741 cagaccttgg cgttaccatt tttgatgact ttaatacttg gttgactggt cttccagtta
    16801 ttggtaatat tgtcggttca tctacttctg cactaggtac ttggtacttc ccagaaggcg
    16861 caatgctctt tgcctttatg ggtatcctga ttggtgttat ttatggtctt aaagaagata
    16921 agattatctc ttccttcatg aatggtgctg ctgacttgct cagtgttgcc ttgatcgtag
    16981 cgattgctcg tggtattcaa gttatcatga acgacggtat gattaccgat acaatcctca
    17041 actggggtaa agaaggcttg agcggtctat cttcacaagt ctttatcgtt gtaacttata
    17101 tcttctatct acctatgtca ttcttgatcc catcttcatc tggtcttgcc agcgcaacta
    17161 tgggtatcat ggctccactt ggagaatttg taaatgtccg tcctagcttg attatcactg
    17221 cttaccaatc tgcttcaggt gtcttgaact tgattgcacc aacatctggt attgtgatgg
    17281 gagctcttgc acttggacgt atcaacattg gtacttggtg gaaattcatg ggcaaactcg
    17341 tagtcgctat tattgtagtg accatcgccc ttcttctcct tggaaccttc cttccattcc
    17401 tataaaatag tgagtgaggt gattccatga aaatagatat aacaaatcaa gttaaagatg
    17461 aatttcttat atcattaaaa accttgattt cctatccttc agtactcaat gaaggagaaa
    17521 atggaacacc ttttggacaa gcaatccaag atgtcctaga aaaaacttta gagatttgtc
    17581 gagacatagg tttcactacc tatcttgacc ctaaaggtta ttacggatat gcagaaatcg
    17641 gtcagggagc agagcttctg gccattctct gtcatttgga tgttgttcca tcaggtgatg
    17701 aagcagattg gcagacaccg ccatttgaag caactatcaa agacggctgg gtattcggac
    17761 gtggtgtcca agatgataaa ggcccttcgc tcgcagctct ctatgcagta aaaagcttgc
    17821 tggaccaagg tattcagttc aaaaagcgcg tacgctttat ctttggtacc gatgaggaaa
    17881 ccctctggcg ctgcatggca cgctacaata ccatcgaaga acaggccagt atgggctttg
    17941 cacctgactc atcttttcct ctgacctatg ctgaaaaagg gcttctacag gtcaaacttc
    18001 atggccctgg atcggatcaa ctagagcttg aagtaggagg cgcctttaac gttgtaccag
    18061 acaaggccaa ctaccaaggt cccctctatg aacaggtttg taacggtctc aaagaagctg
    18121 gttatgatta ccaatccact gaacaaaccg taacggttct cggagtgcca aagcatgcta
    18181 aggatgctag tcaaggtatc aatgctgtca tccgactagc taccattctt gctcctctcc
    18241 aagaacaccc tgctctcagt tttcttgcaa cacaagcagg tcaagacggc acaggaagac
    18301 aaatctttgg tgatatagca gatgaacctt ctggtcacct atcctttaat gtcgcaggtc
    18361 tcatgatcaa tcatgaacgt tctgaaatcc gtattgacat tcggactcct gtcttagctg
    18421 acaaggaaga actagtagag ttgcttacaa gatgtgcaca aaactaccaa ctccgctacg
    18481 aagagtttga ctatctagcg cctctatacg tcgcagaaga cagtaaactc gttagcacac
    18541 tgatgcaaat ctaccaagaa aagactggcg ataacagtcc tgctatttca tccggtggtg
    18601 ccacttttgc tcgcaccatg ccaaattgtg tagccttcgg cgccttattc ccaggagcga
    18661 agcagacaga acatcaggca aatgaatgtg ccgttctaga agatttgtac cgtgctatgg
    18721 atatttatgc cgaagccgtc tatcgacttg caacttaatc aggcaactgt ttctaccaaa
    18781 aaaaatcgac cgattaatga actgcacccc aaaagttaga cagaataaat ctaacttttg
    18841 gggtgtttta ttatgaaatt gagttatgaa gataaagttc agatctatga actaagaaag
    18901 caaggacaaa gcttcaaaca gctttcaaaa agatttggtg tgg
//
LOCUS       DAVBIC010000046        18494 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.046, whole genome shotgun sequence.
ACCESSION   DAVBIC010000046 DAVBIC010000000
VERSION     DAVBIC010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18494)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18494)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18494
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.046"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            6..76
                     /locus_tag="VQ664_001619"
     tRNA            6..76
                     /locus_tag="VQ664_001619"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:38..40,aa:Gly,seq:tcc)
     gene            112..185
                     /locus_tag="VQ664_001620"
     tRNA            112..185
                     /locus_tag="VQ664_001620"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:146..148,aa:Ile,seq:gat)
     gene            192..279
                     /locus_tag="VQ664_001621"
     tRNA            192..279
                     /locus_tag="VQ664_001621"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:226..228,aa:Ser,seq:gct)
     gene            complement(413..850)
                     /locus_tag="VQ664_001622"
     CDS             complement(413..850)
                     /locus_tag="VQ664_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HET2789750.1"
                     /translation="MEQLHFITKLLDIKDPNIKILDIINMDTHKEIIAKLDYEAPSCP
                     DCGSLMKKKEPEKFFGLIEDNLKQVHPIFQTVFKTFLKDKEKIVNALQLHYSNAKLEA
                     TNNLIKLIKCNAFGFRNFENFKKRIFIALNIKKERTKFVLSRA"
     gene            complement(1101..2036)
                     /locus_tag="VQ664_001623"
     CDS             complement(1101..2036)
                     /locus_tag="VQ664_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HET2789751.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTAIWKAIKRLEQE
                     GIEIDSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAASLFKATAPITRNELIIEIWRAFFETPAEELLYLYKKQSFILGKEVTFTLEQKDYK
                     GLAKDISENGKLLVQCDNGKEIWLNSGEISLNSWK"
     gene            complement(2033..2893)
                     /locus_tag="VQ664_001624"
     CDS             complement(2033..2893)
                     /locus_tag="VQ664_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HET2789752.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIT
                     KGQGKFYYKGKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKSPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRARQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYS
                     QYQLVRKATL"
     gene            3001..5163
                     /locus_tag="VQ664_001625"
     CDS             3001..5163
                     /locus_tag="VQ664_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HET2789753.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHSVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATITSYSKLD
                     NNSNQEVVIHKDFSFMADFPAADYEIATLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHIILSEFSKKERPILINNWEATY
                     FDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRQHPDWAIQVPDYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLSYHEIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMIRYFPQVWASDNTDAIARLPIQYGSSYFYPTISMGA
                     HVSAVPNHQMGRMTPLETRGHVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTASNEAAVQFNYGNQTIVTYVRVLSVVETMETTLKLKDLDEEGLY
                     KLQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRKL"
     gene            5255..6514
                     /locus_tag="VQ664_001626"
     CDS             5255..6514
                     /locus_tag="VQ664_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET2789754.1"
                     /translation="MEWYKKIGLLATTGLALFGLGACSNYGKSADDTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNGYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLVKDIVAKGQTPFGIAGADAWTLNGYNQLAFATATGGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKVMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGAGDLAWSISATTKHPKEANAFVEYMTRSE
                     VMQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKQGMVNDLNAFFNPMKADVD"
     gene            6528..7394
                     /locus_tag="VQ664_001627"
     CDS             6528..7394
                     /locus_tag="VQ664_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2789755.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIITIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFLQTSLLGTKWGAIFAAVFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSIVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFFLIVVIS
                     IIQLRVSKKFEI"
     gene            7408..8241
                     /locus_tag="VQ664_001628"
     CDS             7408..8241
                     /locus_tag="VQ664_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET2789756.1"
                     /translation="MKQDERKALIGKYILLILGSVLILVPLLATLFSSFKSTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     AFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIIAGISNGAV
                     K"
     gene            8242..8322
                     /locus_tag="VQ664_001629"
                     /pseudo
     CDS             8242..8322
                     /locus_tag="VQ664_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            8460..9902
                     /gene="gtfA"
                     /locus_tag="VQ664_001630"
     CDS             8460..9902
                     /gene="gtfA"
                     /locus_tag="VQ664_001630"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HET2789757.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFGDAIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKRLGEKYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKDLFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTEILPEIHEHYSIQFKIADHDYYVYDFTLPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTTLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAREVQRPVVKALLNLFSFRNRSEAFDLEGTTEIETPTAHSIVIKRQ
                     NKDKSVTAVAEIDLQNQTYRVIENGVEVSF"
     gene            10040..11233
                     /locus_tag="VQ664_001631"
     CDS             10040..11233
                     /locus_tag="VQ664_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HET2789758.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVLCLYIIS
                     LIFTGDMKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMHSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            11920..13899
                     /locus_tag="VQ664_001632"
     CDS             11920..13899
                     /locus_tag="VQ664_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2789759.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAAKETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KVVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            13966..15462
                     /locus_tag="VQ664_001633"
     CDS             13966..15462
                     /locus_tag="VQ664_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2789760.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGALTFLLALPTIALVY
                     IVRLIGSSIALPDSFPILGAGDWRSYVLPAVILGLLGAPGTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPGAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            15462..16388
                     /locus_tag="VQ664_001634"
     CDS             15462..16388
                     /locus_tag="VQ664_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2789761.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSIRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            16397..17464
                     /locus_tag="VQ664_001635"
     CDS             16397..17464
                     /locus_tag="VQ664_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2789762.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKDWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            17475..18401
                     /locus_tag="VQ664_001636"
     CDS             17475..18401
                     /locus_tag="VQ664_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2789763.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQNIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQAELARYQKGLN"
BASE COUNT         5418 a         3292 c         3871 g         5913 t
ORIGIN      
        1 tttatgcggg tgtagtttag tggtaaaact acagccttcc aagctgttgt cgcgagttcg
       61 attctcgtca cccgctttga actttgttca aattaccaag ttttttaact tgggcgcgta
      121 gctcaggtgg ttagagcgca cgcctgataa gcgtgaggtc ggtggttcga gtccactcgt
      181 gcccattaat tggagaatta ctcaagaggc tgaagaggac ggtttgctaa atcgttaggt
      241 cgggtaactg gcgcaagggt tcgaatccct tattctccgt tttaatgaga gtttgtaact
      301 ctctttttta tttttagaga caataaagct tcagatccgt aaaacttaat tgaattacta
      361 atctgaagtt atttttatgg ctctttgtca actgtagtgg gttgaagaaa agctaagctc
      421 gagaaaggac aaatttcgtc ctttcttttt tgatgttcaa agcgataaaa atccgttttt
      481 taaagttttc aaagtttcga aaaccaaagg cattgcactt gataagtttg atgagattat
      541 tggtcgcttc cagtttggcg ttagaatagt gtagttgaag ggcgttgaca atcttttctt
      601 tatctttgag gaaggtttta aagacagtct gaaaaatagg atgaacctgc ttaagattgt
      661 cctcaataag tccgaaaaat ttctctggtt cctttttctt cattagactt ccacaatcag
      721 ggcaagatgg agcctcataa tccagcttag cgataatttc tttgtgggta tccatattga
      781 tgatatctag aatcttgatg tttgggtctt taatgtctag taattttgtg ataaaatgta
      841 attgttccat atgattcttt ctaatgagtt gttttgtcgc ttttcattat aggtcatatg
      901 ggactttttt tctacacaaa ataggctcca taatatccat agggaattta cccactacaa
      961 atattataga gcccgtttta atgagagttt gtaactctct tttttgtttt tagagacaat
     1021 aaaacttcag atccgtaaaa cttaattgaa ttactaatct gaagttattt ttatatcgtt
     1081 tatattataa ttgtgttatt ttacttccaa ctattgagag aaatttcgcc actatttagc
     1141 cagatttctt ttccgttatc acattgaact aaaagttttc cattttctga gatgtcttta
     1201 gcaagtccct tgtagtcttt ttgctctagt gtgaaagtga cttcttttcc tagaatgaat
     1261 gactgttttt tgtataggta taatagctct tctgctggtg tttcgaagaa agcacgccag
     1321 atttctatga tcaattcatt ccttgttata ggagctgtag ctttaaataa gctggcagct
     1381 ttttctttta attcctgagg gaagtcttta atagtgaaat tgatacctac tccaataatg
     1441 atatctgtga ctaagccagt ttctacagag gtcattgctt cagtaaggat tcctccaatt
     1501 ttatgattgt ttagatagat atcattgacc cattttatgt cgacatctat taaagttagg
     1561 ttcttaatgg ctttgtagac agctccagct acaagtagtg tgtaggatgg taatttgtca
     1621 taggggagat ttggtttaag atggagtgtc atataaatac caccttgtgg tgagtagaag
     1681 gaacgttgaa aacggcctcg gcctgctgtt tgataggaag ctagatagag ggtatttgct
     1741 tcatggccta aatcaattgc ttcttttgca tctagttgtg ttgattttgt ttcgggttta
     1801 aagctgactt taattggaag attttcttct agaatctctg gaagaataag gtcaccattc
     1861 atcagtttat atcctctatt tttgatacta tcaatttcaa tgccttcttg ttctagtcgc
     1921 ttgatggctt tccaaattgc tgttcggctt agggatagtt tttctgcgat tttttctccg
     1981 ctgatatagt cggtttcttt agataggatt tggtagacag cttggtagga tttcataatg
     2041 ttgcctttct cactagttgg tattgagagt attcttttct tgtatgactt ggagtctgat
     2101 taaagtattg tttataagct ttcgaaaaat ggagtggatc tgaaaaacct accgagtatg
     2161 caattacctt gatggactct tgggtatttt cgagaagttg tctagctcgg tgcattcgaa
     2221 cgtagagtag gtattctttg ggtgataagg tattaaattc tttgaatacg cttgataagt
     2281 agcttctgtg aacggatagt tcttttgcta aatcttgaat tgtaagtgat tgaggatagt
     2341 ggctatcaat taatcgtttg cattcaagat agagttggtg ggttgatgaa atattctttt
     2401 ttttctgatt gggagcaata gttcccagat gaaacatcag ttcatgaagt tgtcccatga
     2461 tatggagttg agctaattca cttgattttg taatctgagc gaagcggaca atgtctgaga
     2521 tgagttttgc agtagtctgg gtatgacaag tttcagattg gatgagatag gattgatcag
     2581 aaatttgaga aagagcaaaa taatcagggg atttccctcc agtgattcct aaccagtagt
     2641 aggcccaagg ttctttacta tctgcttgat aaaaggttag ttcctctggt tttaatagaa
     2701 agaaatctcc ttcttttaaa tcaacaattt tacccttgta ataaaatttt ccttgtcctt
     2761 tagtaatgta atgtagaacg tatgtatcac gaatggctgg accaaaagag taattaggtg
     2821 tgcattcctc atatccataa aagcttaggg caaggtcgat tgttccagtc tggtattctg
     2881 aaaaaactaa catgtgctac ctcctaccta acattttacc atattcttga gacatttttc
     2941 tattttggaa agcgatttca ggtgataaaa tataatcaat aaagtgatga ggtgaagtaa
     3001 atgggagtta ggatagagaa taatctattt tatgttgaga gtaaaaatct aagtttgatt
     3061 attgaaaatc gaaatggcta cttacttttg aaacatttag gaaagactat taagaactat
     3121 aaaggttcca atagtgttta tgaacgagac catgcctttt caggaaatcc aacggctact
     3181 aatcgaacct ttagtttaga tactcagcga cagatttttg gacaacatgg cttaggagat
     3241 tttaggaaac caactataca ggttcagcat agtgtaactg aagtaacaga ctttcgattt
     3301 gtagaagcaa agattttaaa aggtcagaat ggtccacagg gcttaccttc tccacatagc
     3361 atggacgata cagagactct tgtcttaatg ttagaagatt ctaaggctca acttagtctg
     3421 actttgtatt atactacttt taataatgat gcgactatta ctagctacag taaattagat
     3481 aataatagta atcaggaagt tgtcatccat aaagattttt cttttatggc tgattttcca
     3541 gctgcagatt acgaaatagc aactctgcag ggtgcttatg ctcgtgaaaa gactgttaga
     3601 cgtcaacagg tagaacaagg aatcttttcg attagttcaa accgaggtgc ttctggtcat
     3661 gctcaaacac cagctcttct actatgcgaa caaggagtca cagaggatgc tgggaatgtg
     3721 tttgctattc aactaatgta tagtggcaac tttgaagctt ttgttcaaaa aaatcaattg
     3781 aatgaagttc gggtggctat tggcattaat ccagaaaact tttcttggaa gttagcccct
     3841 gaggaatact ttgaaacacc ggtagcttta gtgactcatt cagatcaggg attaactggt
     3901 attagtcatg aaagtcagaa ttttgtactg aagcacatta ttctaagtga attttctaaa
     3961 aaagaacgtc caattctaat caataactgg gaagctactt actttgactt tcagagagaa
     4021 aaactgttag agttagcaga tgaagctaag aaagttggca ttgaactttt tgtattagat
     4081 gatggttggt ttggcaatcg ttttgatgat aatcgtgctt taggtgattg ggttgttaat
     4141 gaggaaaaac tgggtggaag tctagaaagt ctgatttcag ctatccatga aagaggtttg
     4201 cagtttggac tttggttaga acccgaaatg atttctgtag atagtgattt gtatcgtcaa
     4261 caccctgact gggctattca ggttcctgac tatgagcata cttattctcg gaatcaatta
     4321 gtacttaatc ttgccaatcc tcaggtagta gaatacttga aaagtgtctt agatcaactc
     4381 ctatcttatc atgagattga ttacattaaa tgggatatga accgcaatat cactaagcta
     4441 gggaatggat taacttatct agagacacag atgcaatctc atcagtacat gctggggctt
     4501 tatgaactcg tttcttatct gacagagaag cacagccata ttctctttga gtcctgctct
     4561 ggtggtggtg gacgaaatga tcttggtatg atacgctatt tcccacaagt ctgggctagt
     4621 gataatactg atgccattgc acgtttacca attcaatacg gttcatccta tttctatcca
     4681 accatttcta tgggggctca tgtgtcagca gtaccgaatc atcagatggg acgaatgaca
     4741 ccattagaaa cacgtggcca tgtagcaatg atgggaaatt tgggctatga gcttgatttg
     4801 acaaatttat cagatgaaga gaaagctacg attgctaatc aggtgaactt gtataaagaa
     4861 ttacgaccag tagttcagtt aggacagcag tatagactaa ttaatcctga tactgcatcc
     4921 aatgaagcag ctgtacaatt taattacgga aatcaaacga ttgtaaccta cgttcgcgtt
     4981 ttatctgttg tagagaccat ggaaacaact ttaaaattaa aagatttgga tgaagaggga
     5041 ctatataaat tacaggaaaa tggcgaagtt tactcaggtg cagaactaat gtatgcgggc
     5101 ttaactgtta tcttatccca aggagatttt ttgagtagac agtatatttt tagaaaacta
     5161 tgatatgtac tgaccccaaa agttagattt attctatcta acttttgaag tgcagtttga
     5221 taagggtgta taaatttata aaggaggctt tctaatggaa tggtataaaa aaatcggact
     5281 tcttgcaact acaggtttag ctttgtttgg gctcggtgct tgctccaact atggtaaatc
     5341 tgcggatgac acagtgacca tcgagtattt caaccagaaa aaagaaatga ccaaaacctt
     5401 ggaagaaatc actcgtgatt ttgagaagga aaaccctaag ataaaggtca aagtcgtcaa
     5461 tgtaccaaat gctggtgaag tattgaagac acgcgttctc gcaggagatg tgcctgatgt
     5521 ggtcaatatt tacccacagt ccatcgaact gcaagaatgg gcaaaagcag gtgtctttga
     5581 agatttgagt aacaaagact acctgaaacg cgtgaaaaat ggctacgctg aaaaatatgc
     5641 tgtaaacgaa aaagtttaca acgttccttt tacagctaat gcttatggaa tttactacaa
     5701 caaagataaa ttcgaagaac tgggcttgaa ggttcctgaa acctgggatg aatttgaaca
     5761 gttagtcaaa gatatcgttg ctaaaggaca aacaccattt ggaattgcag gtgcagatgc
     5821 ttggacactc aatggttaca atcaattagc ctttgcgaca gcaacaggtg gaggaaaaga
     5881 agcaaatcaa taccttcgtt attctcaacc aaatgctatt aaattgtcgg atccgattat
     5941 gaaagatgat atcaaggtca tggacatcct tcgcattaat ggctctaagc aaaagaactg
     6001 ggaaggtgct ggctataccg atgttatcgg agccttcgca cgtggggatg tcctcatgac
     6061 accaaatggg tcttgggcga tcacagcgat taatgaacaa aaaccgaact ttaagattgg
     6121 aaccttcatg attccaggaa aagaaaaagg acaaagctta accgttggtg cgggagactt
     6181 ggcatggtct atctcagcca ccaccaaaca tccaaaagaa gccaatgcct ttgtggaata
     6241 tatgacccgt tcagaagtca tgcaaaaata ctacgatgtg gacggatctc caacagcgat
     6301 cgaaggggtc aaacaagcag gagaagattc accgcttgct ggtatgaccg aatatgcctt
     6361 tacggatcgt cacttggtct ggttgcaaca atactggacc agtgaagcag acttccatac
     6421 cttgaccatg aactatgtct tgaccggtga taaacaaggc atggtcaatg atttgaatgc
     6481 cttctttaac ccgatgaaag cggatgtgga ttaggagtag agagactatg aaaaaagtat
     6541 tacaaaaata ttgggcatgg gcttttgtgg tcatccccct cttgttacaa gcaattttct
     6601 tctatgtgcc gatgtttcaa ggagcctttt acagttttac caactggaca ggattgactt
     6661 acaactacaa atttgtcggc ttaaacaact ttaagctcct cttcatggat ccaaaattca
     6721 tgaatgcgat tggctttacc gcaatcatta cgattgccat ggtggttggt gagattgcac
     6781 tcgggatctt cattgcgcgt gtcttgaact ctaaaatcaa aggccaaacc ttcttccgtg
     6841 cttggttctt cttcccagct gttttatctg gtttgacagt ggctttgatc ttcaagcaag
     6901 tcttcaacta cggtcttcca gcgattggga atgcccttca tattgaattt ctccaaacca
     6961 gtcttttagg gactaagtgg ggagcaatct ttgcggctgt ctttgtcctt ctttggcaag
     7021 gggtggctat gcccatcatc atcttcctag ctggtttgca atctattcca actgagatta
     7081 cagaggcagc aaggattgat ggtgcgacta gcaagcaagt tttctggaac attgaattgc
     7141 cttacttgct accaagtgtc tctatagtct ttatcctagc cctaaaaggt gggctgactg
     7201 cctttgacca agtctttgcc atgaccggtg gtggtccaaa caatgccaca acctcacttg
     7261 ggctcttggt ttataactat gcctttaaaa acaaccaatt cggttatgcc aatgccattg
     7321 ccgtaatctt gttcttctta attgtagtga tttcgatcat ccaattgaga gtatctaaga
     7381 aatttgaaat ttaagaggag aagcatgatg aaacaagatg aaagaaaagc cctgattggc
     7441 aaatacattc tattgattct aggatcggtt ctgattttag tgccgctcct tgctaccctc
     7501 tttagttcct tcaaatccac taaggatatt gtagataatt tctttggctt tccaaccaac
     7561 ttcacatggg acaactttag ccgtctctta gctgatggga ttggaggcta ttattggaac
     7621 tctgtcgtca tcactgtctt gtctttactt gcagtaatga tctttatccc tatggcagcc
     7681 tactccatcg ctcgcaatat gagtaaaaga aaagccttta ccatcatgta taccctctta
     7741 atcctcggaa tcttcgtacc tttccaagtc atcatgattc cgattacggt tatgatgagt
     7801 aaactcggtt tggctaatac ctttggtttg atcttgctct acttgaccta tgcgattcca
     7861 cagaccctct ttctctatgt tggctatatc aaaatctcga ttccagaaag tctggatgaa
     7921 gcagcagaga tcgatggggc taatcaattt acaacctatt tccgcatcat cttcccaatg
     7981 atgaaaccga tgcatgcgac aaccatgatc atcaatgccc tttggttctg gaatgacttc
     8041 atgttgccac tccttgtctt gaaccgggat tccaaaatgt ggactctgcc tttgttccaa
     8101 tacaactacg caggccaata tttcaacgac tacggaccaa gctttgcctc ttacgtggtc
     8161 ggcattatca gtatcaccat tgtctatctc ttcttccaac gccatatcat cgcaggaata
     8221 agcaacgggg cagtgaagta atactcaatg aaaatcaaag agcaaactag gaagctagcc
     8281 gcaggttgct caaaacactg ttttgaggtt gtggatgaaa ctgacgaagt cagtaaccat
     8341 atctacggta aggcgacact gacgtggttt gaagagattt tcgaagagta taacatgaat
     8401 ttgatttacg aagccagatc atatgagact tggcttcaat tagaaaaagg agagtaatga
     8461 tgccaattca aaataaaacc atgttgatta cctattctga tagccttgga aataatctta
     8521 aagacttata tgataatttg gaagagcatt ttggagatgc tattggagga gttcaccttt
     8581 taccattttt cccatcaaca ggtgatcgtg gatttgcgcc agttgactac gacgaagtgg
     8641 actcagcttt tggtgattgg gaggatgtta agcgtttagg tgagaaatat tatcttatgt
     8701 ttgattttat gattaatcat atttctcgtc aatccaagta ttataaggac tatcaagaaa
     8761 aacatgaagc cagtgaattt aaagatctct ttttaaactg ggataagttt tggccagaaa
     8821 accgtccgac acagtctgat gtagatttaa tttacaagcg taaggatcgt gcaccaaagc
     8881 aagagattgt gtttgaagat ggttcagtgg aacatttgtg gaataccttt ggtgaggagc
     8941 agattgatct tgatgtgacc aaagaagtaa ctatggaatt tatccgtaag accattcagc
     9001 acttggcaag taatgggtgt gatttgattc gtctagatgc ctttgcttat gcagtgaaga
     9061 aattggatac taatgatttc tttgtggaac cagatatttg ggatttattg gacaaagttc
     9121 gagatatcgc tgctgagtat gggacagaga ttttacctga gattcatgaa cactattcga
     9181 ttcagtttaa aatagcagac catgattact atgtttatga ttttactctt ccaatggtga
     9241 cactttatac tctttacagt tccagaacag agcgtttggc taagtggttg aagatgagcc
     9301 cgatgaagca atttacgacg ctagataccc atgatgggat tggagtagta gatgtcaagg
     9361 atatcctgac cgatgaggag attgactatg cttcaaatga actctataag gttggagcca
     9421 atgtcaaacg taagtactct agtgccgagt ataacaactt agatatctac caaatcaatt
     9481 caacctacta ttcagcgctt ggagatgatg atgtcaagta ttttctcgct cgtctaattc
     9541 aagcttttgc cccaggtatt cctcaggttt actatgtggg tctattagca ggcaagaatg
     9601 acttgaaatt attagaagaa actaaagaag gtcgaaatat taatcgtcat tactatagca
     9661 acgaggaaat agcaagagaa gtgcaacgac ctgttgtgaa ggcccttctc aatctatttt
     9721 ctttccgtaa ccgttcagaa gcctttgatc tagaagggac tactgagata gagacaccaa
     9781 cagctcacag cattgtaatc aaacgtcaaa ataaagataa gtccgtaaca gcagtagcag
     9841 aaattgattt gcaaaatcag acttatcggg taattgagaa tggagttgaa gtatcatttt
     9901 gaagccttga tatggtggat aaaatagggt ttttattttg gaaaacgttt cctttgtttt
     9961 caaattgcta aaaaagtggt acaatatagg atagcttact attatctgaa tcagctgatt
    10021 tggagagaaa ggattcattt tgaaatcaat aggctttatt gaaaagctga aggggttgtc
    10081 tagtaaagag ctgattttat tgggaattat cctaagtatc tttttaccct tttatctttt
    10141 tgtagttgta ctctgtttat atattatcag tttgattttt acaggagaca tgaaaagtat
    10201 tcttcagaaa atgggggagc atccgatgct gcttcttttt cttagctata gtactgttat
    10261 atccattctt gcacaaaatt ggatgggtct tgtggcttca gtaggaatgt ttctatttac
    10321 tattttcttt ttgcactatc agtcgatttt atcccataaa ttctttcgat tgattttgca
    10381 gttcgtcttg tttggtagtg tcttgtcagc tgcttttgcc agtttagaac atttccaaat
    10441 tgtgaagaaa tttaactatg cttttctttc acccaatatg caggtgtggc atcagaaccg
    10501 ggcagaagtg accttcttta atcctaatta ttatggaatt atttgttgtt tctgtattat
    10561 gattgctttc tatctgttta caacgaccaa gttgaattgg ttgaaagtat tctgtgtgat
    10621 tgcaggcttt gttaatctct ttggtttgaa ctttactcaa aatcgaactg cctttcctgc
    10681 tattatcgct ggagcaatta tctatctctt tacgactatt aaaaactgga aggccttttg
    10741 gcttagtatt ggggtcttcg cgattggttt gagtttcctc ttttctagtg atttgggagt
    10801 tcgaatgggt actttagact cttctatgga agaacgcatt tctatctggg atgctgggat
    10861 ggccttgttt aagcaaaatc ctttttgggg tgaagggcca ttgacctata tgcactctta
    10921 tcctcggata catgctcctt atcatgaaca tgcccacagt ctttatattg atacgattct
    10981 gagttacgga attgtgggta ccattttatt agttttgtct tctgttgctc ctgttcgctt
    11041 gatgatggat atgagtcagg agtcggggaa acgtccgatt atcggccttt atctatcttt
    11101 ccttacagtg gttgctgtgc acggaatttt tgacttggct ctcttctgga ttcagtcagg
    11161 ctttattttc ttgctagtta tgtgcagtat tccattggag catcgaatgt tggtatcgga
    11221 catgacggat taagttttat aagtttgaaa tcttctacct tgggtaggag atttttttat
    11281 acgatgggca tgtcgtgcat ctgaggtgta agtcctctgt agggatccac taccggtgaa
    11341 tacaatagcg ctccccaagc ctgactatcg tgaggtagcg gattaaaatg gtctggggat
    11401 agatcgtttt aagtctgacg caggaaataa gaattgtcag agaaagcaat agtgaaatcg
    11461 taggctatga atagaaacgt gatagcgagg agcatatagt ggataaggta gcgagaaatt
    11521 ttaaagtata aaagatagtc ttaatctata tatgtaaatc acaaaagtaa ttgaattcgg
    11581 aataaggttg gtgtgaaaag acatagtaaa ctgaatcttg aatactagaa tgatacttct
    11641 acaatattgt tataatttaa tttgaattcc aaaatcacat tgttccgtcc gtatttcatt
    11701 ttactgtatg tcttcctaaa ctccaaagtt tctgcgtcaa atttcctatt ttcactgtag
    11761 tctttgacac ttcgaacgac aatttgaatc atatattcaa aaaaaaatga aaaatttgtg
    11821 ccaacaagcc taaatattct gaaaatttgt ttgattttta atggataatg tgatataatg
    11881 gttgtcaatc tataattcac ataaacagag gagtagaaaa tgaaaaaaaa tcgtgtattt
    11941 gctacagcag gtcttgtttt attagcagca ggtgtacttg cagcatgcag ttcttcaaaa
    12001 tcatctgatt catcagcccc taaagcttat ggctatgttt atacagcaga cccagaaacc
    12061 ttggactacc tgatttcaag taaaaatagt acaacagtag tgacttcaaa tgggattgat
    12121 ggtttattca ctaacgataa ttacggtaat cttgctcctg cagttgcaga ggattgggaa
    12181 gtctctaagg atggtttgac ctacacttat aagattcgta aaggggttaa atggtttacc
    12241 tctgatggag aagaatatgc agaggtgacg gctaaagatt tcgtgaacgg tttaaaacac
    12301 gcagcagata aaaaatcaga agctatgtat ttagctgaaa attcggttaa aggcttggca
    12361 gattatctat caggaacttc aacagatttt tcaacagttg gtgtcaaggc ggttgatgat
    12421 tatacgttac aatacacttt gaaccagcct gaaccgttct ggaactctaa gttgacctat
    12481 tctattttct ggcctctgaa tgaagaattc gaaacatcaa aaggaagcga ttttgctaaa
    12541 ccaacagatc cgacatcctt gctttataat ggtccattct tgttgaaagg gttgactgca
    12601 aaatcttctg tagagtttgt aaaaaatgag caatattggg ataaagaaaa tgtccaccta
    12661 gatactatca atctagctta ctatgatgga tcagatcagg agtcgctaga gcgtaacttc
    12721 actagtggag cttatagtta tgcccgtctt taccctacca gctccaacta ttctaaggtt
    12781 gcagaagaat acaaggacaa tatctattac acacaatcag gctctgggat tgctggtctg
    12841 ggtgtgaata ttgatcgcca aagttacaac tatacttcta aaactacaga ttcagagaaa
    12901 gtagctacta agaaggcatt gcttaacaaa gatttccgtc aagccttgaa ttttgctctt
    12961 gatcgctcag cttactcagc tcaaatcaat ggtaaagatg gagcagcttt agcagttcgt
    13021 aatttatttg taaaaccaga ctttgtttca gctggtgaga agacctttgg tgatttagtc
    13081 gctgctcaac ttcctgctta tggtgatgag tggaaaggtg tgaatttagc tgatgggcag
    13141 gatggtttat tcaatgctga caaggccaag gcagagtttg cgaaagctaa gaaagcttta
    13201 gaagcagacg gcgttcagtt tcctattcat ctggacgttc cagtagacca agcatcaaaa
    13261 aactacatat ctcgtattca gtcctttaaa caatctgtag aaacagttct tggtgttgaa
    13321 aatgtcgttg ttgatattca acaaatgaca agtgatgaat tccttaatat tacttactat
    13381 gctgccaatg cttcatctga ggattgggat gtatcgggag gagtttcatg ggggccagac
    13441 tatcaagacc catctactta cctggatatt ttaaaaacaa ctagcagtga aactacaaaa
    13501 acatatttag gatttgataa tccaaatagc ccttcagtag ttcaagttgg tttgaaagaa
    13561 tacgataaat tagttgatga agctgccaaa gagacaagcg acttgaatgt ccgttatgaa
    13621 aaatatgcag cggctcaagc atggttgaca gatagttcac tctttattcc tgctatggct
    13681 tcttctggtg cagcaccagt gctttcacga attgttccat ttactggagc ttctgcgcaa
    13741 acaggctcta aggggtcaga tgtttacttc aaatatttga aattacaaga taaagtggtg
    13801 actaaggaag agtatgaaaa agctcgtgaa aaatggttga aagaaaaagc tgaatcaaat
    13861 gagaaagctc aaaaagaatt ggcaagtcat gtgaagtaaa taatttctaa tagaactttc
    13921 tctccatgag gagaaggttc ttttgggatt tttaaaggaa ataatatgaa aaaatatatt
    13981 tttatgcgtg ttttgcggtc attggtttcg attttcttag taacgacttt gacctacacg
    14041 attatctata ccttggttcc tcgaaaattg attttcaagc aggatcctaa ctataataaa
    14101 attgcaacaa cggctgataa acgtgataac tatgaaaata ctgtgtttga gcgtatgggc
    14161 tacattgagt attacgatac taaagagttg caagaaaagg caagtagcat ggattcttct
    14221 gtaacagtag aagcaaatgc gaccaataaa gctatttatg aaaagtacat caatcaatta
    14281 ggtcatggtt ggactttggg agaatttact gaaagtggtc aattctatgc tactcgtgaa
    14341 attccaattt ttgaacgtgt ttttcacttc tatgctaact tgattgacat tgaccataca
    14401 aataaaatcc aagaccctga aaatccagac ttgaaacgct accttcgttt tgaaaatgat
    14461 ccagctatcg gatggtcatt ggtcggttca ggaactaaac ataaatatct cttgtacttt
    14521 aacagtcagt tcccatttgt tcatcaaaac tttgtgaact tgaatttagg tgactcttac
    14581 ccaacctatg ctaatacacc agttcttcag gttattactc aaggtcaagg acaaaccaaa
    14641 actgcccaag ttcagttccc aacaggtaag aaaacgtctt ctgtaaatat ttactcaaga
    14701 acctacaagt cacctagtca ggctgactct cgtgaagtag ctagctatgg gaaagatgat
    14761 ccttatacag cgactgaaag taattaccaa tatccatcta tgattgtcag ctctgctatt
    14821 actggtttga ttggtttggt tcttgcctat gctcttgccg tgccacttgg ttcagccatg
    14881 gctcgtttca agaacacttg gattgatagc ctctcaacag gggctttgac cttcttgctt
    14941 gctcttccaa cgattgcctt ggtttacatc gttcgattga ttggatcatc tattgccctt
    15001 ccagattcat tccctatctt gggagctgga gattggcgtt cttacgtttt accagcagtc
    15061 atccttggtt tgttgggtgc tcctggtaca gccatttgga ttcgtcgtta catgattgac
    15121 ttgcaatctc aagactttgt tcgtttcgct cgtgcaaaag gtttgtctga aaaagaaatt
    15181 tcaaacaaac acatctttaa aaatgccatg gttccgctgg tttcaggaat tcctggtgcc
    15241 atcattgggg ttatcggtgg tgcaaccctt actgaaacag tcttcgcctt cccaggtatg
    15301 ggtaaaatgt tgattgactc tgtaaaagca tctaataact ctatggtcgt tggtcttgtc
    15361 ttcatcttta catgtatttc tatcttctca cgtcttttgg gagatatttg gatgactatt
    15421 attgacccac gtattaaatt gactgagaaa ggaggcaaat aatgtctaca atcgataaag
    15481 aaaaatttca gtttgtaaaa cgtgacgatt ttgcctctga aactattgat gcgccagcat
    15541 attcttactg gaaatcagtg tttaaacaat ttatgaagaa aaaatcaact gtagtcatgt
    15601 tgggaatctt ggtagccatc attttgataa gtttcatcta cccaatgttt tctaagtttg
    15661 atttcaatga tgtcagcaag gtaaacgact ttagtattcg ttatatcaag ccaaatgcgg
    15721 agcattggtt cggtactgac agtaacggta aatcgctctt tgacggtgtc tggttcggag
    15781 ctcgtaactc catcctcatt tctgtgattg cgacagtgat taacttggtt atcggtgttt
    15841 ttgtcggtgg tatttggggt atttcaaaat cagttgaccg tgtcatgatg gaagtttaca
    15901 acgtcatctc aaacatccca cctcttttga ttgttattgt cttgacttac tcaatcggag
    15961 ctggattctg gaatctgatt tttgccatga gcgtaacaac atggattggt atcgccttca
    16021 tgatccgtgt gcaaatcttg cgctatcgtg acttggaata caacttggca tcacgtactt
    16081 tgggaacacc aaccttgaag attgttgcca aaaatatcat gcctcaattg gtatctgtta
    16141 ttgtgacaac catgactcaa atgcttccaa gctttatctc atacgaagcc ttcttgtctt
    16201 tcttcggtct tggattaccg attacagtgc caagtttggg tcgtttgatt tcggattatt
    16261 cacaaaacgt aacaaccaat gcttacttgt tctggattcc attgacaacc cttgtcttgg
    16321 tatccttgtc ccttttcgta gttggtcaaa acttagcgga tgctagtgat ccacgtacac
    16381 atagatagga gtagaaatga caaaagaaaa aaatgtaatt ttgactgctc gcgatattgt
    16441 cgtggaattt gacgttcgtg acaaagtatt gacagccatt cgcggcgttt cccttgaact
    16501 cgttgaagga gaagtattag ccttggtagg tgagtcagga tcaggtaaat ctgttttgac
    16561 aaagaccttc acaggtatgc tcgaagaaaa tggtcgcatt gcccaaggta gtattgacta
    16621 ccgtggtcag gatttgacag ctttatcttc tcacaaggat tgggaacaaa ttcgtggtgc
    16681 taagattgcg actatcttcc aggacccaat gactagtttg gaccccatta aaacaattgg
    16741 tagtcagatt acagaagtta ttgtaaaaca ccaaggaaaa acagctaaag aagcgaaaga
    16801 attggccatt gactacatga ataaggttgg cattccagac gcagatagac gttttaatga
    16861 atacccattc caatattctg gaggaatgcg tcaacgtatc gttattgcta ttgcccttgc
    16921 ctgccgacct gatgtcttga tctgtgatga gccaacaact gccttggatg taactattca
    16981 agctcagatt attgatttgc taaaatcttt acaaaacgag tatcatttca caacaatctt
    17041 tattacccac gaccttggtg tggtggcaag tattgcggat aaggtagcgg ttatgtatgc
    17101 aggagaaatc gttgagtatg gaacggttga ggaagtcttc tatgaccctc gccatccata
    17161 tacatggagt ctcttgtcta gcttgcctca gcttgctgat gataaagggg atctttactc
    17221 aatcccagga acacctccgt cactttatac tgacctgaaa ggggatgctt ttgccttgcg
    17281 ttctgactac gcaatgcaga ttgacttcga acaaaaagct cctcaattct cagtatcaga
    17341 gacacattgg gctaaaactt ggcttcttca tgaggatgct ccaaaagtag aaaaaccagc
    17401 tgtgattgca aatctccatg ataagattcg tgaaaaaatg ggatttgccc atctggctga
    17461 ctaggaggaa ggaaatgtct gaaaaattag tagaaatcaa agatttagaa atttccttcg
    17521 gtgaaggaag taagaagttt gtcgcggtta aaaatgctaa cttctttatc aacaagggag
    17581 aaactttctc gcttgtaggt gagtccggta gtgggaaaac aactattggt cgtgctatca
    17641 tcggtctaaa tgatacaagt aatggagata tcatttttga tggtcaaaag attaatggta
    17701 agaaatcgcg tgaacaagct gcggaattga ttcgtcgaat ccagatgatt ttccaagacc
    17761 ctgctgcaag tttgaatgaa cgtgcgactg ttgattatat tatttctgaa ggtctttaca
    17821 atcaccgttt atttaaggat gaagaagaac gtaaagagaa agttcaaaat attatccgtg
    17881 aagtaggtct tcttgctgag cacttgactc gttaccctca tgaattctca ggcggtcaac
    17941 gtcaacgtat cggtattgcc cgtgccttgg tcatgcaacc agactttgtt attgcagatg
    18001 agccaatttc agccttggac gtttctgtac gtgcccaagt cttgaacttg ctcaaaaaat
    18061 tccaaaaaga gctcggcctg acctatctct tcatcgccca tgacttgtcg gttgttcgct
    18121 ttatttcaga tcgtatcgca gttatttaca agggtgttat tgtagaggtt gcagaaacag
    18181 aagaattgtt taacaatcca attcacccat atactcaagc cttgctttca gcggtaccaa
    18241 tcccagatcc aatcttggaa cgtaagaagg tcttgaaggt ttacgaccca agtcaacacg
    18301 actatgagac tgataagcca tctatggtag aaatccgtcc aggtcactat gtttgggcga
    18361 accaagccga attggcacgt tatcaaaaag gactaaacta ataatggttt tataatttcc
    18421 atgtcaattt ttatgggaat tataaaactt ttttgttgga ctgatttgaa aaactttgaa
    18481 agcttcctga aaga
//
LOCUS       DAVBIC010000047        17282 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.047, whole genome shotgun sequence.
ACCESSION   DAVBIC010000047 DAVBIC010000000
VERSION     DAVBIC010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17282)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17282)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17282
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.047"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            complement(<1..692)
                     /locus_tag="VQ664_001637"
     CDS             complement(<1..692)
                     /locus_tag="VQ664_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HET2789764.1"
                     /translation="MNIILIAKPLRENTNTKANALNNGWARSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVGSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVGVNTQSYRVQYNLPILADFSVIQDTVEPSRTVVEKIIPKLNIPEEEKGKITEEIKK
                     KKKTSELAELISENVKVRYVDEQGRLLSLKNDTGIGEKESDGTYITNKKQLIGTSYNV
                     TDKKLSSMTTTDG"
     gene            complement(803..1057)
                     /locus_tag="VQ664_001638"
     CDS             complement(803..1057)
                     /locus_tag="VQ664_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789765.1"
                     /translation="MLNVDQDFMSISKSNKSGSDWKKTFTVRITNRLANDLNNVLKQV
                     DKDTPNTPTWLNSAASKAKDDDRVYKLLKTLIPGENYLSC"
     gene            complement(1415..1948)
                     /locus_tag="VQ664_001639"
     CDS             complement(1415..1948)
                     /locus_tag="VQ664_001639"
                     /inference="COORDINATES: protein motif:HMM:NF024751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HET2789766.1"
                     /translation="MTIFKEQESEKVAEFLDILDNLKDLPIVYIDETGIDRYLYRPYA
                     GAPRGEKVYEKISGRRFERTSIVAGQVDGEFIAPMIYKKSMTSDFFVEWFKTQLLPAL
                     KTPHVIVMGNASFHPKNILDELCIQDKHFFLPLPPYSPDLNPIEQAWAILKKKVTDLL
                     REVPTIFECLECFFKTR"
     gene            complement(1935..2261)
                     /locus_tag="VQ664_001640"
     CDS             complement(1935..2261)
                     /locus_tag="VQ664_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2789767.1"
                     /translation="MAYNTDFKQGALDSIKGGHRHVEAAKVFWCWRQNSLHVGKERRE
                     QRNLERKKRVVKKRKIPLEELKAFVEAHPDAFLREIAAHFDCAVPSVWAALKQIKVTL
                     KKDDDL"
     gene            2495..4213
                     /locus_tag="VQ664_001641"
     CDS             2495..4213
                     /locus_tag="VQ664_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HET2789768.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDVEYLKEVKDVNI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPKEWNATAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKIANIEAE
                     INAFVK"
     gene            4324..4671
                     /locus_tag="VQ664_001642"
     CDS             4324..4671
                     /locus_tag="VQ664_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HET2789769.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     AGTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFVHITDGQINVRCDS
                     SMSAQEIKDFAGL"
     gene            complement(4949..5785)
                     /locus_tag="VQ664_001643"
     CDS             complement(4949..5785)
                     /locus_tag="VQ664_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2789770.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPEILKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTTLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(5798..6427)
                     /locus_tag="VQ664_001644"
     CDS             complement(5798..6427)
                     /locus_tag="VQ664_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET2789771.1"
                     /translation="MLELRNINKVFGDKQILSNFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLDNLTLSPVKT
                     MGMKQEEAEKKASGLLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            complement(6437..7078)
                     /locus_tag="VQ664_001645"
     CDS             complement(6437..7078)
                     /locus_tag="VQ664_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET2789772.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            complement(7224..8453)
                     /locus_tag="VQ664_001646"
     CDS             complement(7224..8453)
                     /locus_tag="VQ664_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HET2789773.1"
                     /translation="MNNSQQMLQALEEQDLTKAEHYFAKALENDSSDLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLAL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLILGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLTAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEESENLLT
                     KWMIARSYQEMDDLDTAYEHYQELIGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            complement(8443..9609)
                     /locus_tag="VQ664_001647"
     CDS             complement(8443..9609)
                     /locus_tag="VQ664_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HET2789774.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFLAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            9753..10766
                     /locus_tag="VQ664_001648"
     CDS             9753..10766
                     /locus_tag="VQ664_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HET2789775.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FERMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPDQKFLIVVHQDSDNATVFKRNCDNGRLAELSNDFHVPEAVCIR
                     FAP"
     gene            complement(10811..11230)
                     /locus_tag="VQ664_001649"
     CDS             complement(10811..11230)
                     /locus_tag="VQ664_001649"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HET2789776.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDQVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
     gene            complement(11241..12647)
                     /gene="atpD"
                     /locus_tag="VQ664_001650"
     CDS             complement(11241..12647)
                     /gene="atpD"
                     /locus_tag="VQ664_001650"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HET2789777.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFAGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            complement(12733..13611)
                     /locus_tag="VQ664_001651"
     CDS             complement(12733..13611)
                     /locus_tag="VQ664_001651"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HET2789778.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLADQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            complement(13627..15132)
                     /locus_tag="VQ664_001652"
     CDS             complement(13627..15132)
                     /locus_tag="VQ664_001652"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HET2789779.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYTGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALIHGFLDTVPV
                     DDIVRFEEEFHAFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            complement(15147..15683)
                     /locus_tag="VQ664_001653"
     CDS             complement(15147..15683)
                     /locus_tag="VQ664_001653"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HET2789780.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            complement(15683..16177)
                     /gene="atpF"
                     /locus_tag="VQ664_001654"
     CDS             complement(15683..16177)
                     /gene="atpF"
                     /locus_tag="VQ664_001654"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HET2789781.1"
                     /translation="MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            complement(16191..16907)
                     /gene="atpB"
                     /locus_tag="VQ664_001655"
     CDS             complement(16191..16907)
                     /gene="atpB"
                     /locus_tag="VQ664_001655"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HET2789782.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKLQTI
                     DGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            complement(16942..17142)
                     /locus_tag="VQ664_001656"
     CDS             complement(16942..17142)
                     /locus_tag="VQ664_001656"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HET2789783.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
BASE COUNT         5222 a         3786 c         3096 g         5178 t
ORIGIN      
        1 ccgtcagtag tagtcatgct actgagtttt ttatctgtga cattgtagct ggtaccaatc
       61 agttgttttt tattggtaat gtaggttccg tcactttctt tttctccaat tccagtatca
      121 tttttcaatg atagcaaacg cccttgttca tcaacatagc gaactttcac attttctgag
      181 attagttctg ccaattctga ggtttttttc tttttcttga tttcttcggt tattttccct
      241 ttctcttctt cgggaatatt tagttttgga atgatttttt caacaacggt tcgtgatggt
      301 tccacagtat cttggatgac tgaaaagtca gctagaattg ggagattata ctgaacacgg
      361 taactttgag tgtttactcc tactctttca ttattctctg aaaatacttg tacggtataa
      421 gaaacaacat cttttcctaa tagaacatcc ccagtagaga aatagccgcc ttttcctagt
      481 ttgctatctc cagagcccac ttctttccta attttatcag atagtttttt accagtcagt
      541 acattcgttc gcacaatccc tttgtctacc cctacaaagt gggagaactt tttgaactct
      601 tcagaaccag atctagccca accattatta agggcatttg cttttgtatt tgtattctct
      661 ctcaaaggtt tggcgattag aattatattc atcggcactt agagttgctg ctatatctga
      721 ctcttgaata ccaacttcct tactaccatt tctagcggca gtatatgtgt atttatctgt
      781 ttctacttct agctgattat ccttaacatg ataggtaatt ttctcctggt ataagagtct
      841 tcagtagttt atatactctg tcatcatctt tagctttaga agcagctgag tttagccaag
      901 ttggggtatt aggagtatct ttatcaacct gtttcaagac attattcaag tcatttgcta
      961 gcctattggt tatcctcact gtgaaagttt tcttccagtc tgaaccactt ttattagact
     1021 tagatatgct catgaaatcc tggtcaacat tcaacacaat atcgccttgt tttttagcat
     1081 cttccgttgc ttctgcttca aattgatcat ggagtttttg ttgctctggt gtatagtttt
     1141 tttatttaca cgatttaatg tactattttt tattttagta ttaagaactc cattaatacg
     1201 atttttaaac tctgcttcaa aaaatccctt aatttgttgg tgcgcaagtt caacattcaa
     1261 acctttctta tacaagtctt cattctgata caagtcttca ttctgaacga tttcggctac
     1321 acggtgaatg gtttgatcgt ataccgtctt ctcttaacca gcagtatcct tagttttaat
     1381 gactactcga taggttcctt tagaaccgtt atagtcatct agttttaaaa aagcattcca
     1441 aacattcaaa aatagttgga acttccctta ataaatccgt cactttcttt ttcaagatag
     1501 cccaagcttg ctcaatagga ttcaaatccg gtgaataagg tggtagaggt aagaaaaagt
     1561 gtttatcttg gatgcagagt tcatccaaaa tgttcttggg atgaaaacta gcattgccca
     1621 tgacaataac atgaggtgtc ttcaaagcag gtaggagttg cgttttgaac cactccacaa
     1681 agaaatcgct tgtcatgctt ttcttgtaaa tcatgggagc tataaactct ccgtctactt
     1741 gtcctgcaac aattgaagtt cgctcaaaac gacgtccgct aatcttttca tagactttct
     1801 cccctctagg agcccctgca taaggacgat agaggtagcg gtcgattcct gtttcatcaa
     1861 tatatacgat tggtaaatct tttaggttat ccaaaatatc aagaaactca gcgactttct
     1921 ctgactcttg ttccttaaag atcgtcatct ttttttaaag tgaccttaat ctgctttaaa
     1981 gctgcccata ctgaaggaac agcacaatca aaatgtgccg caatttcccg taaaaaagca
     2041 tctggatgag cctctacaaa ggctttcaat tcttctaaag ggatcttacg ctttttgacg
     2101 actcgctttt tccgctctaa gttcctttgt tcacgtcttt cttttcccac gtgaagagag
     2161 ttctgacgcc aacaccaaaa aactttggcc gcctcgacat gtctgtgccc tcctttgatg
     2221 gaatctaatg ctccttgttt aaaatcagta ttatatgcca tagctttatt agaccatgct
     2281 tattttaaac taagcaacta tatcaatgtt ttgttatgag aagacttact ttttttactg
     2341 aaattgaatt tttcctagcc tcaacatcat ataaccccaa aattcaatct gacctggttt
     2401 gaagagatgt tcgaagcaga taaggtttta ctaaaactaa aaaaaatgat ataatcaaac
     2461 tgattaaatg ttttaaaaat aaaggagaat ttgaatgtct taccaagaaa attaccagaa
     2521 atgggttgat tttgtggagc ttcctgacta ccttcgtcaa gatttggaaa atatggacga
     2581 aaaaactaag gaagatgcct tctatacaaa tcttgaattt ggtactgcag gtatgcgtgg
     2641 cttggttggt gctggtacaa accgtatcaa catctacgtt gttcgccaag ctactgaagg
     2701 attggctcgt ttgattgagt caaaaggtgg aaacgagaaa gaacgcggtg tagcaattgc
     2761 ctacgatagc cgtcacttct cacctgagtt tgcctttgaa tctgcggcag ttcttgctaa
     2821 acacggcatc aaatcttacg tatttgaaag ccttcgtccg actccagaac tatcatttgc
     2881 agttcgtcat ctcaactgtt tcgcaggtat catggtcaca gccagccaca accctgctcc
     2941 atttaacggt tacaaggttt acggtgaaga cggtggacaa atgcctccac acgatgcgga
     3001 cgctttgact acttatatcc gtgcaatcga aaacccattt gcagttgaag ttgctgatgt
     3061 ggaaactgaa aaagcttctg gcttgattga agttatcggc gaagctgttg acgtagaata
     3121 ccttaaagag gttaaggacg taaacatcaa cccagccttg attgaagaat ttggtaaaga
     3181 catgaagatt gtctacacac cacttcatgg tactggtgaa atgttggctc gtcgtgctct
     3241 tgcccaagca ggatttgact ctgttcaagt tgttgaagcg caagcaactg ctgacccaga
     3301 cttctcaact gtaacatctc caaacccaga aagccaagca gcctttgccc ttgctgaaga
     3361 acttggtcgt caagttggtg cagatgttct tgtcgcaact gacccagacg ctgaccgtgt
     3421 tggtgttgaa gttcttcaaa aagatggtag ctacctcaac ctttcaggta accaaatcgg
     3481 tgctatcatg gctaaataca tcttggaagc tcacaaaaac gctggaactc ttcctgaaaa
     3541 tgccgctctc tgcaaatcta tcgtttcaac tgacttggta acgaagattg ctgaaagcta
     3601 cggcgcaact atgttcaacg tcttgacagg tttcaaattt atcgctgaaa aaatccaaga
     3661 attcgaagaa aaacacaacc acacttacat gatgggattt gaagaaagct tcggttactt
     3721 gattaaacca tttgtacgtg ataaagatgc catccaagcc gttcttgtcg ttgctgaact
     3781 tgctgcctac taccgttctc gtggtttgac acttgctgac ggtatcgaag aaatctataa
     3841 agaatatggc tactacgcag aaaaaacaat ctctgttact ctttcaggtg tcgatggtgc
     3901 tgaacaaatc aaagcgatta tggctaaatt ccgcaacaat gctccaaaag aatggaacgc
     3961 aacagctatc actgtcgtag aagacttcaa ggcacaaact gctactgttg ctgacggtac
     4021 tgttacaaac ttgacaactc ctccaagtga tgtgttgaaa tacacacttg ctgacggttc
     4081 atggattgcc gttcgccctt caggtacaga accaaaaatc aagttctaca ttgcagttgt
     4141 aggagaaacc aacgaagaat cacaagctaa gattgctaac atcgaagcag aaatcaatgc
     4201 atttgtaaaa taaagaccta taaaagatga gaccaaccaa cctcatcttt tttcgtatca
     4261 aatctaagca attttagaaa ctttatggca tactagactt atcaatgaaa gcgaggtaat
     4321 ctcatggaac aatttttaga taacatcaaa gaccttgaag tcactacagt tgtgcgtgcg
     4381 caagaagctc ttgataaaaa agaaactgca accttcttta tcggtcgcaa aacttgccct
     4441 tactgccgta aatttgcagg tacattgtca ggtgtcgtag ctgaaaccaa agctcacatt
     4501 tacttcatca atagtgaaga accaagccaa ctcaatgatt tgcaagcatt ccgctcacgc
     4561 tatggaatcc caactgtacc aggttttgtt catattacag atggacaaat caacgtccgt
     4621 tgcgactctt caatgtcagc acaagaaatc aaagatttcg caggattgta aaaaatcagc
     4681 taacaagtct taaaatcaca aaaacgcata atgtaaggtg caaaaacctt gatattatgc
     4741 gttttattgt tcctaaaaca gttacatcag catttcatta cagaacattt taattttgga
     4801 agtcaaatca atttttaaca atgttttaga aatcacagtg ggctattcca tattaaatta
     4861 tccagattca atcgctatta tcgttttcct agattacaaa aaaactgcgt tttgctaatc
     4921 aaaacgtagt ctcagccact attttatctt actgtccttc ttttacttct ttggttgcta
     4981 catcttctcc aaaccatttt tggctgattt cttggaactt gccgtccttg taaagactag
     5041 aaaaagcttc atttatcttc ttaaccaagg ttgtatcttc cttacgggct ccaaccgcaa
     5101 aagcttctgt ttctagtcca actgtaaaga cattataatc gtttaaaaca ccttctgctt
     5161 ctaaataata gtttgcatag acacggtcaa tcaatagacc atcaattcga tcgtttttca
     5221 aatcaatcaa ggcttcatta aaggtttggt attgattcgc ttccttatta gcgacaatat
     5281 tcttcaaaat ttctggattt gcttcaaagt ccgcataacc agatgaacca gcttgagctc
     5341 ctaatgtctt tccagtcata tcctttgcag tcgtgatacc agatgatttc ttcgtaacca
     5401 atacctgctc attcttcata tatgagttac tgaaagccac cttttcacgg cgttcgtctg
     5461 tagcggaata gccattccaa atcagatcaa tcgttccttt tgtcaattca gcttctttca
     5521 aatcccaatc aatcggttgc caatttaccg tgattccgta tttttcaaaa acagctgtag
     5581 ctaaatcaat atcaaatcct gcataagaac catctttctg agcaaatccc attggaacaa
     5641 aagtactatc aaatccaata gtaatagact tgttagactg gtactttgac caattatctc
     5701 cactagtttc gctagaattt ttcccacaag ctactaagaa caaagcagtc atcagactga
     5761 ctaatacaag catccatttt ttcatccatt tttcctccta tttaggttct actttcaata
     5821 atacatctgc gatattttca gcaaactgca aatcatgggt aaccacaatc tgggtcatcc
     5881 caagttccct attttgcaag attagcttct ccacttccaa acgtaattct ggatccaggg
     5941 cagaagttgg ttcatcgtag ccaatgattt ctgggtcaat catcatagca cgcgccaaag
     6001 ccacccgctg cttttgccca ccagatagtg agaaaggata ggcctctgcg tgtcctccta
     6061 gtcctaactg ttccaagagt ccactcgcct tcttctcagc ctcttcctgc ttcattccca
     6121 tggtcttcac aggcgataag gtcaaattgt ccagaactga taaatgaggg aacagttgaa
     6181 aatcttggaa tacaaatccc agtagattgc gcttctgcaa ttcatccagc tctaaaggtt
     6241 gtccattata aaagatttgc cctgaatcaa tggtttcaag acctgcaagc atacgtaaaa
     6301 gagttgtctt acctccacca gaaggtccaa cgatagccag gatttgcttt tcaggaatac
     6361 ttagactgaa attagacagg atttgtttgt ctccaaagac tttattgata tttcgtaatt
     6421 ctaacatggc agcctcctat ctataataac tatacttctt ctcaactttt ttggaaataa
     6481 ttgtcacaat cccaatcaaa atcaaataaa tggctcctgc caagaacata ggaactagac
     6541 tagcatcgcg gttagcagct gttcgactag ccaagataag gtctgaaatt ccgagagcat
     6601 agaccaaaga agtatccttg accaaactca taacttcatt aaagacacta ggaagaacga
     6661 tcttggtcac ttggggcaag ataatatagc gcactctgtc aaaagggcta aacttcaaga
     6721 ccttggcggc ctcatactgt cctcttggaa tagtgtcaat tcccccacgg aaaatttctg
     6781 caaagtaagc tgcatagttg agaacaaagg caataatagc tgcaggaagg cggtctaaac
     6841 gaatcccaat acttgggagc acataataga taaaaatcag ttgcaagagt aagggggttc
     6901 ctcgcataac ccagatgtaa atgttaatca gataatggag gggcttccaa tggacttgca
     6961 aggcaaaggc aatcaaaacg cccaagggaa tcgaaaatag caagaccagt gcaaagacct
     7021 gtacagtcgt gctcgcacca ttcagtaaac tcggtaatat ctcaaataaa taagacatac
     7081 tgcacctcct aaaagtaatt gttcctatta tagcatgaat aaacaagatt accaagtatt
     7141 tttgtaaaaa gattctacca tatacaaata aaaaccgtag ctatcaaaag agataaacta
     7201 cagttctata tgtttaaaca ttcttacaat ctctcaaaca gttcttgcat ttgcacatca
     7261 tctggaacca gttttaagta agtgtgagca tggacttttg cttcttcaaa atgtcccaat
     7321 tcacgcaaga gatagatata gtgttccaga aattctggat tgtccttcaa atctcctatc
     7381 aactcttgat aatgctcata agcagtatcc aaatcgtcca tttcttgata agaacgagca
     7441 atcatccact tggtcaaaag attttctgac tcctcactct gcaagtctag aatatcctca
     7501 taacgctcct gctccagata aatagtggct aaacgaagca agatttcttc tgtatcctca
     7561 gcgtcttctt ttgcagtaag gagataattt tctgcaccac tagcatcatg caattcataa
     7621 gaaaattgtg aagcagctag caagaggcga gtttcaaagg gatttttctc taatccttgc
     7681 ttagcgatac gcagggcttc ttgaacttga tgttccttat gtaaagcctg actgtaccca
     7741 tactcatagc cttcaaagtc aggagaaatg gtatcaagct gcttaaagta gagggtggct
     7801 ttttgatatt cttcttgatc aaaataaaga ctggccaact caaaagctgt taagtcatcg
     7861 tattctaact ccagggcttt ttctaaaaac tcagtagccg tttcaaattt ccctaactga
     7921 gcataggcaa agccaattcg ttgataggtg gaaatgcccg tttgctcata aatcgagcga
     7981 ttatctaact gggcataggc ttgaatagcc gcttggtaat tttccaactc actatccaac
     8041 tctgccaaac ccaatatcaa gagagaatcc tctgagtagg tcaaggcctc caataatttc
     8101 tcacgtgcca catctgtcaa accttccagc tggtaaaggt ctgccttcag agccaaagac
     8161 gagacatacc agtcactgtc agcttggatt tcctcaagat aggtaaaggc ttcttctatt
     8221 tgaccatcct cgctagcaat tgcagctaga ttaagatgaa cctctggaaa atcctctaca
     8281 attttcaggt aaatttcctt ggcctgagga tagaaaccaa tcccttcaag ataagttgcc
     8341 aactcataca gaagatcact tgaatcattt tctaaagctt tggcgaaata atgctcagcc
     8401 ttagttaaat cttgctcctc caaagcctgt aacatctgtt gactattgtt cactcttgac
     8461 ttcctcaccc tctaattcat atagaccact gactacctta taccattcga aaatggctga
     8521 aatgacaacc ttagcagagg cataaaccgg aataccaagt aaaactcccc agataccaaa
     8581 catagatcct gaagttaaca aaacaaagag aacattaata gggtggatgt ttaattgact
     8641 tcccaaaatc aatggagaga caaaacggcc ttcaatagtt tgttctacga taaagacaat
     8701 cactactttc aaaagcatga ctggaccagc aatcaaaccc aatactagag caggaagcat
     8761 ggctagaaag ctaccaagat aagggaccag atttaaaata ccagcagtaa cccccagcgt
     8821 aaccgcatag cgtagaccaa taatcttgaa gaagatgata aacattactg ctacaataat
     8881 agccactgtc acttgccctc gaacatagtt ggacaactgt tgattcacat ctgataaaac
     8941 ttgtccaaca ggttccttca attttcttgg aatgaattgg gtcaaatagt tacgcaagcc
     9001 tttcccatca cgcaagagat aaaagagcat gaaaggaacg ataatcaagg caacaatcac
     9061 ttgagaagct ccgctaataa aggcactcac ccagttgact gcctgagatg aaaccttact
     9121 tgccaaaact gtagcctggc tagaaaaatt ggtcaaaact tgctctaatt gaggtctgaa
     9181 atcatctggc aggtgctggg ctaccaatcc attaacaatc ctatctatat cttctaagta
     9241 aacaggaacg tttcttgcaa aggtcaaaac ctgacgttgc agatttggaa tggcgactgc
     9301 caagccccaa atgataaaga gagcgatgat aacaaagaca atagtgatag ctataacacg
     9361 attaacctta tgcttctcca tccaatcaac aataggattc aacaaataat ataacaaacc
     9421 agacaaaatg actggcaaca tcacaactgc taaaaagtct aaaacaggtg aaaatagaaa
     9481 actaatctta cttaaaataa aaagattcag tcccaataat aaggttacta aaaataccgt
     9541 aattgccttg ttatctaaaa accacttgaa aaaccaagat aggctaaaat gtttctcttt
     9601 ttgctccata aatacttcct ttctattgtt ctctcattat accatttttg aaacaaaata
     9661 actctttttt aaagtgctta catctaattg gatatcttta atttacttgt ttttgtgata
     9721 taatagtctt atctttacac agaggtatag taatgaaaga aactgtttat tttggaactt
     9781 atacacgtcg tacttctcaa gggatttaca aggcagactt tgatacagaa actggtcagc
     9841 tttcaaatct agaacttttt gcagctgagc caagtccaac ctaccttgcc tttgaccagc
     9901 accaacattt atacactgtt ggtagccaag acgataaggg gggaattgca gcctatcaaa
     9961 ctgacgggac tgtgttaaat catgttgttg aagaaggagc tccccactgt tatgttgctg
    10021 tcgatgaaaa gcgtgatttg gtttacgcag ccaactatca caagggacaa gtccttgttt
    10081 ataaacgcca ggaagatggt agtcttctac ttagtgatat ggatcaacac agtggccaag
    10141 gtccacatga aaatcaagct tccccccatg ttcactatac agatttaaca cctgaccact
    10201 atctagtgac ctgcgacttg ggaactgacc aagtcatcac ctatgacctc gatcaagaag
    10261 gaaaattatc taagctctat acctatcaca gcaagccagg agcaggctca cgccatatca
    10321 ttttccataa ccactataaa atcgcttatc tcatttgtga actcaatagt actatcgaag
    10381 ttttaatcta cgatggcgtt ggcgaatttg aacgtatgca ggtcatttca actttaccgg
    10441 aagcttacga aggctttaat ggaaccgctg ctattcatct ctctaaagac ggtaaatacc
    10501 tctacgcttc taaccgtggc catgattcta tcgcagtata taccatcctt gcggacggta
    10561 gcttagagtt attagaaatc gttccaacgc atggtcagac tccacgtgat tttgatttga
    10621 cacccgacca aaaatttctc attgttgtcc atcaagactc tgacaatgca actgtcttta
    10681 aacgtaattg tgacaatggt cgtctagcag aactctccaa cgacttccat gttcccgaag
    10741 cagtctgcat ccgttttgct ccttaaaaca ccataaaaaa tgaacttggt attttcaagt
    10801 tcattttttc ttatagtcta tttccgacat taatacggtt aatagcacgt tgcaaagcaa
    10861 tcttagcacg acgttcttgg tcaatcaaat gtttgtcttg tgcttcttca attgcacgtt
    10921 ctgcacgaag tttggcacgt tctgcacgac tgatatcgat atcacgagca cgttctgcag
    10981 agtcagcgac gattgtgatc atatcattgg caatttcaat aacaccaccg tttactgcaa
    11041 tccagttcac ttgatcttta tcatcgatac gttttacctt tacttcatca actgctaaaa
    11101 ccgcaatcat attttcatgt cgtggcaaga tccccatctc accatccaga gttcgaaccg
    11161 atacatagct ggcatggtga tcatagacga gaccatctgg tgtcacgatc tggacagtta
    11221 actgagccat agttcacctc ttaaaatccc attttttcag cttttgcaat cacatcttcg
    11281 atagaaccta caccacggaa ggcatcttct ggcaagtggt cgtatttacc atcaaggatt
    11341 tccttaaagc cacgtacagt ttcagcaact ggaacataag aacctggctg accagtaaat
    11401 tgttccgcaa cattgaagtt ttgtgacaag aagaactgga tacgacgggc gcgagcaacc
    11461 aaggtctttt cttcatcaga aagttcatcc ataccaagga tagcaatgat atcttgcaat
    11521 tcatggtaac gttgaaggac acgttttact tcagcagcaa ctgcatagtg ctcttctcca
    11581 acgatttcag gtgccaaggc acgtgagctt gaagcaagtg ggtcaacggc tgggtagata
    11641 cccaattgta ccaacttacg ttccaagttt gttgttgaat ccaagtgagc gaaggctgtt
    11701 gctggcgctg ggtcagtata gtcatccgct ggcacataga tagcctggat agaggttaca
    11761 gaacccttct tggttgatgt gatacgttct tgcaattgac ccatttccgt agcaagtgtt
    11821 ggttggtaac caacggctga tggcatacga cccaaaaggg cagatacttc tgaaccagcc
    11881 tgagtgaaac ggaagatatt atcgataaag agaagcacgt cttggccttc cacatcacgg
    11941 aagtattcag cgattgtcaa accagtaagg gcaacacgca tacgtgctcc tggtggctca
    12001 ttcatctgac caaagaccat ggctgttttc tcgataacgc ctgattcttt catttcccag
    12061 taaaggtcat tcccctcacg agtacgttcc ccaacaccag caaatactga aataccaccg
    12121 tgctcttggg caatgttgtg aatcaattct tggattaaga cagttttacc aactccggca
    12181 ccaccgaaaa gtccaacttt accaccttta aggtaagggg caagaaggtc aataaccttg
    12241 atccctgttt caaggatttc agaagaggta gacaactcat caaaagttgg agctttttta
    12301 tgaattggct gacgctctgc gtcttctgta aaaggagctt ccaagtcaat ggtatctccc
    12361 aaaacgttga agacacgtcc caaagtttct ttacctactg gtacagagat tggacgacct
    12421 gtgtccaata cttccattcc acgagtcaac ccatctgttg attccatggc gatagtacga
    12481 accataccat ctcctaactc caaggctact tcaaggacga tttttgtttt tctttcgtca
    12541 tttttgtaga cgacaagtgc attgttaatc tcaggaagtt tttcccctgc tgcaaacaaa
    12601 acgtctacaa cgggaccgat aacctgagca attttacctg aactcatctc cttctcctat
    12661 tctatataag atactgtcgg ttcctagctc aactaggtcc taagttcatt ttcatacgag
    12721 ctggactaga gcctattcta aggcactagc acctgctacg atttctgtaa tttcttgtgt
    12781 aatcgccgcc tgtctggcac ggttatactg aattgtcaaa tcattgatga ctttcttagc
    12841 attatctgtc gctgtttgca tggctgtcat acccgcagca ttctcagctg tcttggcatc
    12901 tataatggca ccgtaaatca tactttctgc aaactgaggc aacaactgct ccagaatttc
    12961 ttctcggctg gtttccaatt caaaagtcaa gctgtactct tcatccgctt catttggatc
    13021 caagtcaaca atcggaagca tttgttccac acgcatttga ctggttagcg tattgacatg
    13081 gtggttgtag caaacataaa gctcatcaaa gagttcattt tggtacattt caacagtttt
    13141 tgaaataatc ttacgaactt gatcaaagct aggttggtct gccaagccac gtaattcata
    13201 aagtggttga ataccgcgag ccttaaagaa atcagctccc atcccaccga tacagatcat
    13261 ttcaaaacct ttaccgtctg ggtggtattc ttctttcaac tccataacag ctttcaaaat
    13321 agaggaatta taacctccaa ccaaaccgcg gtctgaagtg ataacgatat agcctgtctt
    13381 cttcacagaa cggctaatca acatcggatt agttgaagca ccagctccat taccatgaag
    13441 gatatctgtc aaaagtttac gcactttctg agcgtaaact tggaagttgc gagcagcttc
    13501 ttcagagcga cctagcttag cagccgatac catttgcatg gcattagtga tttgactcgt
    13561 attttttgtt gaggcgattt ttgttttaat atcatttaga gatactgcca tctgacacct
    13621 ctattcttat tggaagctag attgattgag aaactctgta atcgcagcat ccaagactgc
    13681 ttcttctggc aagtcttttg tatcacgaat ggtttccaaa atctctggat gttgagcatc
    13741 aaagaaggca tggaactctt cctcgaaacg aacaatatca tctactggaa cagtatccaa
    13801 gaaaccatgt atcaaagcat aaagaatggt tacttgtttc tcaacaggta atggtttgtg
    13861 aacaggttgt ttcaagacct caacggtacg acgtccacgg ttcaacttag cctgtgttgc
    13921 tgcgtccaag tcagaaccaa acttagtaaa ggcttccaac tcacggtatg aagcaaggtc
    13981 gatacgaagt gtaccagcaa ccttcttcat ggctttgatt tgtgcagaac cacctacacg
    14041 agatacagat gaacccgcat cgatggctgg acgaatacct gcattgaaga ggccatcgcc
    14101 aaggaagatt tgtccatcag tgatagaaat cacgttggtt gcgatatagg ctgagatatc
    14161 tcctgcttgt gtctcgataa atggtagggc tgtaattgat ccaccaccaa gttcatcaga
    14221 aactttagct gagcgctcaa gcaaacggct gtggagatag aaaacatccc ctgggaaggc
    14281 ttcacgacct ggaggacgac gaagcaagag cgacagttca cgataagcta ccgcttgttt
    14341 tgatagatca tcgtatacaa tcaaaacatg cttaccttga tacataaatt cttccgccat
    14401 agcgacccca gtataaggag ctaggaagag caatggagat ggttgtgaag cagaggctgt
    14461 cacaacgatt gtgtagtcca aggcaccgta ctgacgaagt gtttctactt gcgtacgaac
    14521 tgttgattct ttttgtccaa tcgcgacgta gatacagatc atatcttgat ctttttggtt
    14581 caagattgta tcaatcgcaa tggttgtttt ccctgtctga cggtcaccga taatcaactc
    14641 acgttgacca cgaccaatcg gtacaagggc gtcaatagct ttcaaaccag tttgcaatgg
    14701 ttctgaaaca gacttacgtt gcataacacc aggagctggt gcttctactg gacgagtttt
    14761 atcagtgtgg atttctccaa gaccgtcaac tggacgacca agcggatcca caacacgacc
    14821 aatcagactt tcacctacag ggacttccat gattttccct gtacggcgga ttgtatcgcc
    14881 ttcacggata tctgtaaagt cacctaggat gataatacca acgtctgttg actccaagtt
    14941 ttgagccata ccataagagc cgttttcaaa attcaacaac tctccactca tgacattttc
    15001 aaggccgtga gcacgcgcga taccgtcccc gatataggtt acaacacctg tttcagtcac
    15061 atcaaaattg ggtttgaaat tttcaatttg ttgcttaatt aaagcgctga tttcttgtgc
    15121 gttaattgcc aaaagaacac cactttctat ttcaaatttt ctttaacaac tttaagttgt
    15181 tgtttaatac tcacatcaat tgtcttgtga ttggcaaaaa tgacaaaacc accaatgaga
    15241 ctttcatcga tttgttcttt tacactcctt actttcagag acattttttt ctcaatcaaa
    15301 gggagcaaac gagtcttctg ttcatcagtt agaggatgag cagacgtaat cgtcacttca
    15361 aatcgatttg tttctttttc aagtcggttc aagcaatcta caagcacatc ataaaaaaga
    15421 tttgctctgt gattgtaggc cagaacctgg ataaagtttt gtaataaagg cgacacagaa
    15481 tcttggaaaa aagcaattgt tttttcctta tccgactcgt ctactgccac ttgttttaaa
    15541 aaagaaggca gacctgtttt ttcaacaact tgcttgattt gagtcaagtc tgaaaagata
    15601 cggtcttctt ctcctttttc aagtaccaat tggacaaaag gcatgctgta tttttcaatt
    15661 acctttactg ttttcttgtc cattaagctt ctcctagctg atcgatatac tgatcaatga
    15721 gtgctttatg ggcatgactg tcaaggtttt gtgagatgat tttaccagct aagctgatgg
    15781 tcagatctgc gacctcaccc ttaacactct gtaaagcttc tactttattt tgagcaattt
    15841 cttgattggc tttttctttt aagtgtcctg cttctagttt agcatctgct aagatattag
    15901 ccttactttg ctcagctgtt tcctttgcat tttcaatgat tgtcttagct tctttacggc
    15961 taccagccaa ttcatcttcg cgtttttgag ccaatacttc tgctttttga cgggcttctt
    16021 cagctctgtc aatatctgaa gcaatttttt cagctctttc ttcgaaaatg cctgtaatat
    16081 tagaccatgc aaatttttta atcaagacta gcaaaagaat aaaagagcca gtgattaaaa
    16141 taaaattacc aattaattca cctactgtta cgtgcatcag ttactccttt ctattcctct
    16201 tcaatattaa tcttattccc taaatacaca gatgtcaaaa gagtaaaaac ataagcttgg
    16261 atgcaggaaa taaagacaga aaatgcagtc caagccaaat tagctccaaa ggctactgga
    16321 taccaataaa tagcttggtg ggaaagaaga agtaacaaac tcgtcatgac ctctcctgca
    16381 aagatattcc caaaaatccg caaagccaaa gataagaagt ttgtaaattc ttccaagata
    16441 ttcatcggta tgacaaaaac aggactcata aaagatttta tacttttttt aaatccacga
    16501 cgacgaacgc tttctatatg tgtcaacaaa atgacaagaa aagataaggt taagtcatac
    16561 tgtaaattag cggttggcga actccaccag ttagtcccat cgatcgtttg aagctttgtc
    16621 attaagccaa ggttattggc aatcaccatg aaaaggaata aacaaaggaa aaagagtgaa
    16681 taatctttca tgtagcgcga accaatgtta ggttctgtaa atccaataac aaagtcatag
    16741 acatactcaa gtacattttg ctttcctttg ggtttcaagg tcatattgcg gcttgcccaa
    16801 taaataaaga caaaaataac tcccacaatc aacaaagtca tggctaacat agtcagattg
    16861 aagataacag gaccaataga gatgattgga ttaatacttt cttccatcta aaatcctccc
    16921 ttttcttctc gttccatgta tttatttgat aataaatgag aagacaagag ttacaaagaa
    16981 agttccttca ataaaggcaa cacctaaaaa catcaaacta cgaaactcag aaagcatatc
    17041 tggttggcgt gctactgatt taaacagtcc attcatcaat aaaccttcac cgacagatac
    17101 gcccatacag gcaatacata agcctaaaaa tgttaaattc ataacaaatt ctcctttaaa
    17161 ataaaattta cttacttagt gtagtcctaa aatttaaatt tgtcaacttt taaccgctat
    17221 tggaagcgtt taataaaaat tatttccatt ttgctaaatt tcaagttcaa gttagccatc
    17281 ca
//
LOCUS       DAVBIC010000048        16744 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.048, whole genome shotgun sequence.
ACCESSION   DAVBIC010000048 DAVBIC010000000
VERSION     DAVBIC010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16744)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16744)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16744
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.048"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            63..527
                     /locus_tag="VQ664_001657"
     CDS             63..527
                     /locus_tag="VQ664_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase"
                     /protein_id="HET2789784.1"
                     /translation="MGGHPGFNCLLLDDEVYEDYYLEFEKEEICSVPRPFPETGMLDF
                     QDRSPWLEGQKEIDLSYDLFSTDAVTLDELQSRTIALRSLKHDKGLKVHFAEFPNLII
                     WSTLNKGPFITFEPWSGLSTFLEEGDHLEDKKNVCLLEANQVEELGFEIEVL"
     gene            685..1110
                     /gene="lacA"
                     /locus_tag="VQ664_001658"
     CDS             685..1110
                     /gene="lacA"
                     /locus_tag="VQ664_001658"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HET2789785.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG"
     gene            1141..1656
                     /gene="lacB"
                     /locus_tag="VQ664_001659"
     CDS             1141..1656
                     /gene="lacB"
                     /locus_tag="VQ664_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HET2789786.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPSEENKKLIAKIEHLESHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            1667..2596
                     /locus_tag="VQ664_001660"
     CDS             1667..2596
                     /locus_tag="VQ664_001660"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HET2789787.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDDQVKKDFFSIQGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQDFLEHFKKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKLVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLEELKEVLQESLFTGIEWI
                     IVSLGANGTFAKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLHKESDAGLLIKA
                     NVLGMLNAQEKMTGHVNMANYQALYDQLIVKEV"
     gene            2598..3578
                     /gene="lacD"
                     /locus_tag="VQ664_001661"
     CDS             2598..3578
                     /gene="lacD"
                     /locus_tag="VQ664_001661"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HET2789788.1"
                     /translation="MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKILVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGEAAAREWLRTTGFENIDELNKVLQTTATSWKERV"
     gene            3812..4648
                     /locus_tag="VQ664_001662"
     CDS             3812..4648
                     /locus_tag="VQ664_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HET2789789.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIVIGKGIAFGKKKGDLIAENH
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALIQGRYKDSNLPDISAKYPVAFQIANEAFEIYRQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLTDYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            4684..5001
                     /locus_tag="VQ664_001663"
     CDS             4684..5001
                     /locus_tag="VQ664_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET2789790.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            5003..6697
                     /locus_tag="VQ664_001664"
     CDS             5003..6697
                     /locus_tag="VQ664_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HET2789791.1"
                     /translation="MDKLIIFIEKGKPFFEKLSRNIYLRAIKDGFISSMPAVLFSSIF
                     ILIAAVPNIFGFKWSDEQLAFILKPYNYSMGILALLVAGTTAKSLTDSVNTRSMEKTN
                     QINYMSTFLAAVVGLLILAADPIEGGFANGLLGTRGLLTAFLAAFITVNIYKVCIKNN
                     VTIRLPEEVPPNIAQVFKDVIPFALSVLSIYGLDLIVRNIFGTNVAESVGKILAPLFS
                     ATDGYIGLAIVFGAYAFFWFVGIHGPSVVEPLIVAISYANIEANVQLVQAGMHADKIL
                     NPVTQTFVVTMGGTGATLVVPFMFMWLCKSKRNRIVGRASVVPTFFGVNEPILFGAPI
                     VLNPIFFIPFVTAPIINVWIMKFFVDVLQMNSFSIILPWTTPAPIGIVMGTALAPLSF
                     VLAITLIIIDTLIYYPFVKVYDHQILEEERSGKSNDELKEKVAANFNTAKADAILEKA
                     GVDAAQNTITEETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLP
                     EFDLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQAQFD"
     gene            6906..8312
                     /gene="lacG"
                     /locus_tag="VQ664_001665"
     CDS             6906..8312
                     /gene="lacG"
                     /locus_tag="VQ664_001665"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HET2789792.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTGYGQVNAKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKDKGYKGEIGVVHAL
                     PTKYPLDPKNPSDVRAAELEDIIHNKFILDATYLGRYSAETMEGVNHILSVNGGSLDL
                     REEDFTALEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     VAPDYVPRTDWDWIIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKQHLEVLSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            8355..8537
                     /locus_tag="VQ664_001666"
     CDS             8355..8537
                     /locus_tag="VQ664_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000471575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HET2789793.1"
                     /translation="MFKDFIQSIYEKVYIINFEKCSQIPCLTSEELKSLFLNFINPEE
                     WDTISFDSDFMPFQQS"
     gene            complement(8815..9576)
                     /locus_tag="VQ664_001667"
     CDS             complement(8815..9576)
                     /locus_tag="VQ664_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET2789794.1"
                     /translation="MLKQEKLAKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFNKFDF
                     YTFYNVSNLDTIVSDSKLSDSILFKLSKHIKVIKP"
     gene            complement(9758..10720)
                     /gene="nrdF"
                     /locus_tag="VQ664_001668"
     CDS             complement(9758..10720)
                     /gene="nrdF"
                     /locus_tag="VQ664_001668"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HET2789795.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD"
     gene            complement(10908..13067)
                     /gene="nrdE"
                     /locus_tag="VQ664_001669"
     CDS             complement(10908..13067)
                     /gene="nrdE"
                     /locus_tag="VQ664_001669"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HET2789796.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWAELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            complement(13148..13366)
                     /gene="nrdH"
                     /locus_tag="VQ664_001670"
     CDS             complement(13148..13366)
                     /gene="nrdH"
                     /locus_tag="VQ664_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HET2789797.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPGKLKQLA"
     gene            13717..13980
                     /locus_tag="VQ664_001671"
     CDS             13717..13980
                     /locus_tag="VQ664_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HET2789798.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
     gene            13986..15719
                     /gene="ptsP"
                     /locus_tag="VQ664_001672"
     CDS             13986..15719
                     /gene="ptsP"
                     /locus_tag="VQ664_001672"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HET2789799.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            15974..>16744
                     /gene="phtA"
                     /locus_tag="VQ664_001673"
     CDS             15974..>16744
                     /gene="phtA"
                     /locus_tag="VQ664_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtA"
                     /protein_id="HET2789800.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIFSEE
                     LLMKDPNYKLKDEDIVNEVKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTPRNDGAVALARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRGNLSNSRTYRRQNSDNTSRTNW"
BASE COUNT         5253 a         2942 c         3481 g         5068 t
ORIGIN      
        1 aactagaatt ctagttttgc aggaagtcta ataaagaaac tagcaaggtc aggccttact
       61 ttattggtgg acatccagga tttaattgtc ttctacttga tgatgaagtc tatgaagatt
      121 attatctaga gtttgagaaa gaagagattt gctctgttcc acgtcctttc ccagaaacag
      181 gtatgttgga tttccaagat agaagtccat ggctagaggg acaaaaagaa atagatctta
      241 gttatgatct tttcagcaca gatgcagtga ctttggatga attgcaatct cgaacaattg
      301 cccttcgttc tcttaaacat gataagggat tgaaagtgca ttttgcagaa tttccaaacc
      361 tcatcatctg gtcaactttg aacaagggac ctttcattac ctttgaacca tggtctggct
      421 tgtcaacatt ccttgaagaa ggagatcatt tagaagataa gaagaatgtt tgtctcttag
      481 aagccaatca ggttgaagaa ttagggtttg agatagaagt tttataaaaa aagtaaaaaa
      541 taaataacaa aaacaaacac aaactgttga cttcttcaaa caatagtagt atattatgtt
      601 tgtgaggact aattgactgt tttttaaaga cagccaatac actgctggaa tccagcatag
      661 aaaaaataaa aaggagtata caatatgtct attgttatcg gtgcagatgc tgcaggtttg
      721 agattgaaag aagttgtgaa agacttctta gaaaaagaaa acttccacct tgtggatgtt
      781 acagctgaag gtcaagactt tgttgatgtg actctcgctg ttgctgcaga agtaaacaaa
      841 gaagaacaaa accttggtat cgtgattgat gcttatggag ctggtccatt tatggttgca
      901 actaagatca aaggaatggt tgctgcagaa gtatctgacg aacgttcagc ttatatgact
      961 cgtggccaca acaactcacg tatgatcact atgggggcac aacttgttgg tgatgaattg
     1021 gctaaaaaca tcgctaaagg atttgttaat ggtaaatacg acggtggacg tcatcaaatc
     1081 cgggttgaca tgttgaacaa aatgggctaa ttagattaca gtaagaaagg taagttaaaa
     1141 atgagaattg caattggatg cgaccacatc gtaacagatg aaaaaatggc ggtttcagaa
     1201 tttttgaaat caaaaggata tgaagtcatt gactttggta catatgacca tacacggact
     1261 cactacccaa tctttggtaa aaaagtaggg gaagctgtaa ctagcggcca agctgatctt
     1321 ggggtatgta tctgtggtac tggtgttggt atcaacaacg ctgtaaataa agttccaggt
     1381 gttcgttctg ccttggttcg tgatatgaca acagcccttt atgctaaaga acaattgaac
     1441 gctaacgtta tcggctttgg tggtaagatt actggtgaat tgcttatgtg tgatatcatc
     1501 gaagctttca ttcatgctga atacaaacca tctgaagaaa acaagaaatt gattgcgaaa
     1561 attgaacacc ttgaaagtca caatgctcaa caaacagacg caaacttctt tacagaattc
     1621 cttgaaaaat gggatcgcgg agaataccac gactaagagg tgacctatga ttttaacagt
     1681 cacaatgaac ccatccattg atatttccta tcccttggat gagttgaaga ttgatactgt
     1741 caatcgtgtg gtggatgtaa ccaaaacggc tggtggtaag ggacttaatg ttacccgagt
     1801 actttcagaa tttggtgatt ctgttcttgc tactggttta gtgggtggca aacttggtga
     1861 gtttttggtt gaacatatcg atgatcaagt aaagaaagat ttcttttcta ttcagggaga
     1921 aactcgtaac tgtatcgcta ttctccacgg tgacaaccaa acagaagttc ttgaaaaagg
     1981 tcctgaagta ttggaacagg aaggtcaaga ctttttggaa catttcaaaa aactcttgga
     2041 gtcagttgaa gtagtagcca tctcaggtag tctgccagct ggccttccag ttgattacta
     2101 tgcgagcttg gtagagcttg ctaatcaagc tggcaagcta gtagtcttgg actgctctgg
     2161 tgcagcactt caggcggttc ttgaatcacc ccataaaccg acagtaatca aacccaataa
     2221 tgaggaattg tctcagcttc taggaagaga agtttctgag gatttggagg aattaaaaga
     2281 agtccttcaa gaatctttgt ttacagggat tgaatggatt atcgtttcac ttggtgccaa
     2341 cggtactttt gccaaacatg gtgacacttt ctacaaggta gatattccta gaattcaggt
     2401 ggtaaatcct gttggatctg gagactctac tgtggcagga atttcttcag gacttcttca
     2461 caaagaatcg gatgcaggat tactcatcaa ggcaaatgtc cttggtatgc tcaatgctca
     2521 agaaaaaatg actggtcatg tcaacatggc caactatcaa gctctatatg atcaattaat
     2581 agtaaaagag gtataaaatg gctttaacag aacaaaaacg tgtacgctta gaaaaacttt
     2641 ctgatgaaaa tggtatcatc tcagctcttg catttgacca acgtggtgct ttgaaacgcc
     2701 tcatggctca acaccaaaca gaagaaccaa ctgtggccca aatggaagaa cttaaaatct
     2761 tggtagcaga tgaattgact aaatacgctt catctatgct tcttgaccct gagtatggac
     2821 ttccagcaac taaggctctt gatgaaaaag ctggtcttct ccttgcttat gaaaaaacag
     2881 gttatgacac aacaagcaca aaacgcttgc cagactgctt ggatgtttgg tctgcaaaac
     2941 gtattaaaga agaaggtgca gatgcagtta aattcttgct ttactatgat gtagatagct
     3001 cagacgaact caatcaagaa aaacaagcct acatcgaacg catcggttct gagtgtgtgg
     3061 ctgaagatat cccattcttc cttgaaatcc ttgcttacga tgaaaaaatt gcggacgcag
     3121 gttctgtaga atacgctaaa gtaaaaccac acaaagttat cggtgctatg aaagtctttt
     3181 cagacccacg ttttaacatt gatgtcttga aagttgaagt tcctgttaac attaaatatg
     3241 ttgaaggctt cgctgagggt gaagtggttt acacacgtga agaagcagca gccttcttca
     3301 aagcgcaaga tgaagcaacg aacttgccat acatctactt gagtgctggt gtatcagcta
     3361 aactcttcca agatactctt gtatttgctc atgaatcagg tgcaaacttt aacggagttc
     3421 tttgtggtcg tgctacatgg gcagggtcag ttgaagctta catcaaagat ggtgaagcag
     3481 cagctcgcga atggcttcgc acaactggat ttgaaaacat tgatgagctc aataaagttc
     3541 ttcaaacaac agcgacttca tggaaagaac gtgtgtaaga aagtcctcct agtttaggaa
     3601 catgaatcta aaaaaattta aaaaaagttg tatgtaaagg tttacaaaat aacttacttg
     3661 tgctatactt aaatcacaag ttaatacaag gtgagtgtta ctaagtaata ttaggcatga
     3721 tcacaggtga attagaaatc agctgatttt ctagttcatt tgtggtcatt ttttgtactc
     3781 atataccttt aagatataaa aggaggttga catgtatcga attctaaatc caatgaatca
     3841 caatgtctcg cttgtcagaa atgataaggg agaagaggtg attgtaattg gtaaggggat
     3901 tgcattcgga aagaagaagg gggatttgat tgctgaaaat catgttgaga aaatctttcg
     3961 gatgaagacc gaagagtcca gagaaaactt tatggctctt ctcaaagatg ttccgcttga
     4021 ttttatcaca gtgacctatg aaatcattga taagctatca aagaaatatc attatccgat
     4081 tcaagagtat ctctatgtaa ccttgacaga tcatatttac tgttcttatc aagctctaat
     4141 tcaaggaagg tacaaggata gtaatctgcc agatatttct gctaagtatc ctgtcgcttt
     4201 tcaaatcgca aatgaagctt ttgaaattta ccgtcagaag ctagcagatc attttcctga
     4261 ggacgaaatt attcggattg cttatcattt cattaatgct gaaggtgaaa atgaagtgga
     4321 acttgtggag tcgattgata agaggaaaga aattctcagg aatgttgaag aagttttaac
     4381 ggactatgca attcaacgaa ctaaaaagaa taaccatttc tatgatcgct ttatgatcca
     4441 tttgaattat ttcttggatt atttagacag atctagagat gataaccaat cacttctgga
     4501 tatggaagat catattaaac aatcctatcc aaaagccttc gagattggtt ccaagatcta
     4561 tgatgtgatt acgcaacata cgggtcttga tttgtataaa agtgaacgag tttatctagt
     4621 tctacatatc caacgtttat tgtcataaaa atttatttaa aactatataa ggagaattct
     4681 atcatgaata gagaagaagt aacattgtta ggttttgaaa tcgtagccta tgctggcgat
     4741 gctcgttcaa aactattgga agccttgaag gctgctgaag ctggtgattt tgaaaaagcg
     4801 gacgctctgg tagaggaagc tggtagctgt attgcagagg ctcaccacgc gcaaacaagt
     4861 ctattgacta aggaagcttc tggtgaggac ttagcgtata gtgtgaccat gatgcatggt
     4921 caagatcact tgatgacaac tatcttgtta aaagacctaa tgcaccattt aattgaactt
     4981 tacaagagag gagttaaata aaatggataa gttaataatt tttattgaga aaggaaagcc
     5041 tttctttgag aaattatcga gaaatatata cttaagagcg ataaaagatg gttttatttc
     5101 cagtatgcca gcagtattat tctcaagtat ttttatacta atagctgctg tgcccaatat
     5161 ttttgggttt aaatggtctg atgaacagtt agcttttatt ttgaaacctt acaactactc
     5221 aatggggatt ttagctctct tagtagctgg gacaactgca aaatcgttaa cagattcagt
     5281 taatacacgt agtatggaga aaaccaacca aatcaactac atgtcaactt ttttagcagc
     5341 tgttgttgga ttgttaatac tggcagctga tccaattgaa ggtggatttg ctaatggtct
     5401 tttaggtact agaggattac ttactgcatt tttggcagct tttattacag taaatatcta
     5461 taaagtatgt attaaaaata atgtaaccat tagacttcct gaagaggttc caccaaatat
     5521 tgcacaagtt tttaaagatg ttattccgtt tgccttatct gttctttcaa tatatggatt
     5581 ggatttaatt gttagaaata tttttggtac aaatgtagca gaatctgttg gtaaaatatt
     5641 agcccctcta ttttcagcta ctgatggtta tatcggttta gctattgtat ttggtgctta
     5701 tgctttcttt tggtttgttg gaattcatgg gccatctgtt gtagaacctt taattgtagc
     5761 tatcagttat gcaaatatag aagctaatgt tcagcttgtg caagctggta tgcacgcaga
     5821 taaaatttta aatccagtta ctcaaacttt tgttgtaaca atgggtggta ctggtgcaac
     5881 actagtagtt ccatttatgt ttatgtggtt atgtaaatca aaaagaaata gaattgtcgg
     5941 acgtgcgtct gtagttccta ctttctttgg cgtaaatgaa ccaatcctat ttggtgctcc
     6001 aattgtttta aatcctatct tctttattcc gtttgttact gctcctatta tcaatgtttg
     6061 gattatgaaa ttttttgtag atgttctaca aatgaatagt ttcagtatta ttttaccttg
     6121 gacaacacct gctccaattg gtattgttat gggaacggcg ctggctccat tgtcattcgt
     6181 cttggctata actttaatca ttatcgacac tttaatctat tatccatttg ttaaagttta
     6241 tgaccatcaa attttagaag aagaacgttc aggtaagtct aatgatgaat tgaaagaaaa
     6301 agttgctgca aacttcaaca ctgcaaaagc ggatgctatt cttgaaaaag cgggtgtcga
     6361 tgcagcacaa aataccatca ctgaagaaac aaatgtcctc gttctctgtg caggtggagg
     6421 aacaagtggt ctccttgcaa atgctttgaa taaggcagca gcagaataca atgtccctgt
     6481 gaaagcagca gcaggcggct atggtgctca ccgtgaaatg ttaccagagt ttgatcttgt
     6541 tatccttgcc cctcaagttg cttcaaactt tgaagatatg aaagcagaaa cagataagct
     6601 cggtattaaa ctagcgaaaa cagaaggcgc tcaatacatc aaattaactc gtgatggaaa
     6661 aggtgctctt gcattcgtac aagcgcaatt cgattaaggc tagagactct gaaatagtct
     6721 cctatcgtta cggaaatcgc tatggcgaat ttcctattat taattcgtcg gtaaaaagat
     6781 atcgttttta cctcctcatg tcacaattcg gtgacttggt acaagaagtg agatggagaa
     6841 ggatggctca ctgactcctc tcctctcact tttactttat ttaaatcaag aaataggtga
     6901 aaaaaatgac aaaaacactt ccaaaagact ttatttttgg tggcgcaaca gctgcctatc
     6961 aagcagaagg tgctacacat actgatggta aaggaccagt agcgtgggat aaatatcttg
     7021 aagataacta ctggtacact gcagaaccag ccagtgattt ttacaatcga tatccagttg
     7081 acctcaagct agcagaagag tatggtgtca atggtattcg aatttctatt gcttggtcac
     7141 gtattttccc gactggttac ggccaagtaa atgctaaagg tgttgagttt tatcataatt
     7201 tatttgcaga gtgtcacaaa cgtcatgttg agccctttgt aactcttcat cactttgaca
     7261 cgccagaagc tctccactca aatggagact tcttaaaccg tgaaaatatc gaacattttg
     7321 tagactacgc tgccttctgt tttgaagaat ttccagaagt aaactattgg acaaccttta
     7381 atgaaattgg gccaattggt gatggtcaat acttggttgg gaaattccct ccaggtattc
     7441 agtacgacct tgccaaagtc ttccaatcgc accacaatat gatggtgtct catgcgcgtg
     7501 cagttaagct atataaagat aaaggctata aaggcgaaat tggtgttgtt cacgctctgc
     7561 caactaagta tcctttagat cctaaaaatc cgtcagatgt tcgtgcagct gagttggaag
     7621 atattattca caataaattt atcttggatg caacttatct aggtcgctat tcagctgaaa
     7681 cgatggaagg tgtcaaccat atcttatcag tcaatggtgg tagcttggat cttcgtgaag
     7741 aagattttac agcattagaa gcagcaaaag acttgaatga tttccttgga atcaactact
     7801 atatgagtga ctggatggaa gcctttgatg gagaaactga aattatccat aatggtaagg
     7861 gtgagaaagg aagttctaaa taccaaatca aaggtgttgg tcgtcgtgta gctcctgatt
     7921 atgtaccacg tacggattgg gattggatta tctaccctca aggtttatat gaccaaatta
     7981 tgcgtgtgaa gaaagattat cctaactaca agaagattta catcactgaa aatggtctcg
     8041 gctataaaga tgagttcgtc gataacactg tttatgatga tggacgtatt gattatgtga
     8101 aacaacactt ggaggtcttg tctgatgcga ttgcagatgg agcgaatgta aaaggttact
     8161 tcatttggtc attgatggac gtcttttcat ggtcaaatgg ttatgaaaaa cgttacggtc
     8221 tcttctatgt agactttgaa actcaagaac gttatccgaa gaaatcagct cactggtaca
     8281 agaaagtagc ggaaactcag attatagact agtagaatta gtcattagat atagaatttt
     8341 agtgagtcaa aaagatgttc aaagatttta tccaatctat ttatgaaaaa gtttatatta
     8401 taaatttcga aaaatgctct caaataccgt gtttgacgag tgaagaattg aaaagtctat
     8461 ttttaaattt tatcaatcct gaagaatggg atactatctc ctttgattca gattttatgc
     8521 catttcaaca atcgtaacca atttctcaaa aaagttaaat cttatattta gtactctgca
     8581 aaactcttat ctaatcacgt tgcttatact caatgaaaat caaagagcaa ctttaaacta
     8641 ggaagcgagt cgcagatttc tcaatgcata gctttgagga attgggcaaa aagtctttga
     8701 tatagaaaaa gcatagtatc aggtgtttca acacctgata ctatgctttt tattgtggga
     8761 agatttactt tttttcttct gaaattgagt tgttacccag gctctttcag tttattaagg
     8821 cttgatgact ttaatgtgtt tagatagctt aaaaaggatt gaatcactta gtttagaatc
     8881 tgaaacaata gtatcaagat ttgatacatt ataaaaagta taaaaatcaa acttattgaa
     8941 cttactatga tctgcgagta aatatttttt attagaatta tttaaagcga tgcgttgagc
     9001 ctctccctct tcctcgctaa aagtagctag agctccgttt tgaataccat tacagctaac
     9061 gaaagcttta gaaaattgga gattagagag attttgtagg gtcaatgtgc caacaaaagc
     9121 acctgtaata tcgcgataat ttccacctat caaaatcaaa tctgttaatt ttcgttcgct
     9181 taaaatcaga aaaacaggta gactgttggt tacgacgcgg atattgtcaa taggcaactc
     9241 acgcgcaaaa aactctaatg ttgttcctgg tccaatgaaa atagtttctc tttcttctac
     9301 tagactgcct gcaaaatggg ctatttcttg tttttctgcc gtttggaggg cttgtttttc
     9361 aatatttgat cgctcattag tcaaaaggga gttggttcga agtttttcag ctccaccatg
     9421 cacacgaatc agcaaatctt tatcagctaa ttcctgtaaa tagcgccttg cagtcatatc
     9481 tgaaacggct atttcgtcca taatctgttt aactgttatg gttcctttac tatttactat
     9541 ctctaaaatt ttggctaatt tttcttgttt gagcatatta tcacctcgtt tcctactact
     9601 atcttaccat aaacaaactc atcattcaaa tacaaaaaca acaaaatgaa acaaaaacaa
     9661 aaatatcgaa gtttgttttc aaaactttcg atatttttgt tgggttataa ctttgatgtt
     9721 tctagtttac tttttgatga ttgagagtga tggagaatta gtctaaaccg tagttatagt
     9781 catcgtcttg catggcttca acttcgccaa gaaggtaacc atttccgact tgagagaaga
     9841 agtcatggtt ggaagttcct gttgaaatac cgttcataac gattgggttg acatcttcag
     9901 ctgaatctgg gaaaagtgga tcttgtccca tgttcatgag agctttattg gcattgtagc
     9961 gaaggaaggt tttaacctct tcagtccaac caacaccgtc ataaagactc tctgtgtagc
    10021 cttcttcatt ttcataaaga gtatagagta ggtcgtacat ccattctttg agtttttctt
    10081 gctcttcttc aggcaattca ttgaaaccaa gttggaattt gtaaccaatg taggttccgt
    10141 gaacagactc gtcacgaata atcaatttaa tgatttctgc aacgttggct agtttgttgt
    10201 taccgagata gtagagggga gtgaagaaac cagagtagaa gaggaaggtt tcgaggaaga
    10261 cgctggcaac tttcttttca agtgggctgc cgtttaggta gatttcgttg acaatctcag
    10321 ccttcttttg taggtaagga ttggtattgg tccattcgaa aatttcttca atctcagcct
    10381 tagtattcaa ggtagaaaag attgatgagt aagatttagc gtggacagat tccataaatt
    10441 ggatgttatt gaaaacagct tcctcatgtg gtgtacggat gtctgcgcga agggcttgaa
    10501 ccccagtttc agattgcata gtgtcaagaa gggttaaacc accaaaaact tttccgacca
    10561 agtctttctc tttgttagat agctttctcc agtcatccaa gtcgtttgat aagggaatac
    10621 gtgtatcgag ccaaaattgc tccgtcagtt tttcccaagt tgatttgtcg atgacatctt
    10681 cgatggcatt ccagttaatg gctttgtagt aagtttccat ttaaaatctc tttctgtgtt
    10741 tagtattgcg aactcacaat tatttctact ttaccataat tctataggag tatcgcacaa
    10801 aaagtcggaa gcccgacttt taaaatgtta cataaattat gttatgacat agtagatttg
    10861 attttatcag tgctgcttag ggaaaaataa tgtttctatg ctagaaacta aatcacacag
    10921 ctttcacatt ggttggcgcc gacttctcca ccgtcatctg taaaggtacg gacgtagtag
    10981 atagacttga ttcccttgtt aaaggcatag ttacgaagga tggacaagtc acgtgtcgtt
    11041 tgtttatttt ccctcttcca ttcgtaaagg ccttttggaa tgtcactacg catgaagagg
    11101 gtgagtgaaa gtccttgatc cacgtgttca gtcgcagcag cgtaaacatc gatgacttta
    11161 cgcatatcca tatcgtaggc agaagtgtag taaggaatgg tttctgtaga caagccagca
    11221 gcagggtagt agattttacc aattttcttc tcttggcgtt cttcgatacg ttgcgtaatc
    11281 gggtggatag aagcagaaac gtcgttgata tagctgatag aaccatttgg cgctacagca
    11341 aggcgatttt ggtggtaaag accatcttct tgaaccttgt cgcgaagttc agcccaatca
    11401 gcaacaccag ggataaagac atttttgaag agttctttaa cacggtctga tgttggaaca
    11461 aattcaccag ttacatactt gtcaaagtaa cttccgttag catagtctga tttttcaaag
    11521 ttgtggaagg taataccacg ttcacgcgca atattgtttg actctaccaa ggtccagtag
    11581 ttcataagca taaagtagat gcttgtaaat tcaacagact caggtgaacc atattcaatg
    11641 agttgttggg caaggtagct gtgcagtccc atggcaccga gaccaaaggt gtgggcttgg
    11701 ctatttccat ggtcaatcgt tggtacagct acgatatgtg aactatctgt aacgaaagta
    11761 agggcacgaa ccatagcacg gatagaacga ccaaaatcag gtgaagtcat catgttaacc
    11821 acgttggttg aacccaggtt acatgaaaca tctgttccca tttgaaggaa ttcttgagca
    11881 tcgttgatca agcttggttc ttgaacttga agaatctcag aacacaagtt actcatgata
    11941 atctttccat caacaggatt tgcacggtta gccgtatcga tgttgactac ataaggatag
    12001 ccagactctt gttgcaattt agagatttca gtttccaaat cccgcgcctt gatttttgtc
    12061 ttgcgaatat ttggatttgc gaccaattca tcgtattttt cagtaatgtc gatgtaattg
    12121 aatggcacac cgtattcttt ttctacagag taagggctga agaggtacat ttcttcattt
    12181 ttacgagcca attcgtagaa tttatcaggt actacaacac caagtgatag agtcttgaca
    12241 cgtacttttt catcagcgtt ttctttctta gttgaaagga aagcgatgat atctgggtga
    12301 aagacgttga ggtagacaac accggcacct tgacgttgcc ccaattggtt ggagtaagag
    12361 aagctgtctt caaaaagctt cataacagga acgacacctg aagcagctcc ttcatagcct
    12421 ttgataggtg caccagcttc acgaaggttg ctgagggtaa ttcccacacc accaccaata
    12481 cgtgaaagtt gaagagctga gttgatagaa cgtccgatag agttcatatc atccgtcact
    12541 tggattagga aacaagatac caactctcca cggcgagcac gtccagcatt caagaaggaa
    12601 ggagtagcag gttggtagcg ttggtggatg atttcattgg caatatcgat tgcaacagct
    12661 tcattcccat cagcgaaata aagggcgttg aagaagacac ggtcttccat attttcaaga
    12721 tagtattcac cgtcattagt ctttaaggca tattgattgt aaaatttata agctgccatg
    12781 aatgacttga attggaagtt ttggtctttg ataaattgag ctaattcttc caagaactct
    12841 ggacggtatt tcttgataaa ggctgtttcg atgtagttgt gttcaatgag gtaattgatt
    12901 ttgtctttga ttgaatcaaa aaccatagtg tttggaacta cattttcttt aaagaaagca
    12961 tccaaggctt ccttgtcttt atgaagcatg atttgtccat taacaggacg gttaatttcg
    13021 ttattaagac ggaagtaagt cacgtcttca agatgtttta atcccataaa atttccctta
    13081 tctaattaca aaagaaaggc ttctaagtta gccctaaaag cagtttcttc tggatgatgt
    13141 actaagatta tgctaattgt ttcagttttc ctggttggaa acctgaaaag acttcagttg
    13201 gtgtttggat aacaggagct gcgctaaaac cgagctcttt aacttgatcg acgtactcag
    13261 gttgctcatc aagattgatt tcacgataag agacattatt actgtccaag aaacgcttgg
    13321 tcattttaca ttggacacaa ttgtttttag aataaacggt taccattgtg taactcctct
    13381 tcaaaattta atactatctt agtatatcag aaaataaaat tttgtcaatg atttgaacta
    13441 aatatagtgg tgttcttttg ttgtttttat atataaacac aatatatagt gtttgtattg
    13501 tgaaatagca atgattatcc tataaattgt ttttaaagaa actatatcct gtgttttgtt
    13561 atctaggata gaagattttc agcaagttat ctgaaaggaa attgaaggaa aatccagaaa
    13621 atgcttgaaa aaaatcctag aagatggtat aatactaaat tgtaagggtt atcacatata
    13681 actcaaaaaa agaaagaaca aaaggagagt caaactatgg cttctaaaga tttccacgta
    13741 gtggcagaaa caggtattca cgcacgtcca gcaacattgt tggtacaaac tgctagcaaa
    13801 tttgcttcag atatcactct tgagtacaaa ggtaaatcag ttaaccttaa atcaattatg
    13861 ggtgttatga gtcttggtgt tggccaaggt gctgacgtaa ctatctcagc tgaaggtgca
    13921 gatgcagatg acgctatcgc tgcaatctca gaaacaatgg aaaaagaagg attggcataa
    13981 gggaaatgac agaaatgctt aaaggaatcg cagcatctga cggtgttgca gttgcaaaag
    14041 catatctact cgttcagccg gatttgtcat ttgagactat tacagtcgaa gatacaaacg
    14101 cagaagaagc tcgccttgat gccgctctac aggcatcaca agacgagctt tctgttattc
    14161 gcgagaaagc agtaggtacg ctcggtgaag aagcagctca agtttttgat gctcacttaa
    14221 tggttcttgc tgacccagaa atgatcagcc aaatcaagga aactatccgt gcgaagaaag
    14281 tgaatgcaga agcaggtctg aaagaagtta cagatatgtt tatcactatc tttgaaggca
    14341 tggaagacaa cccatacatg caagaacgcg cagcggatat ccgcgacgtg acaaaacgtg
    14401 tattggcaaa ccttcttggt aaaaaattgc caaacccagc ttctattaat gaagaagtga
    14461 ttgtgattgc gcatgacttg acaccatctg atacagctca attggacaaa aactttgtaa
    14521 aagcttttgt aaccaacatt ggtggacgta caagccactc agctatcatg gcacgtacac
    14581 ttgaaattgc tgctgtatta ggtacaaata acatcactga aatcgttaaa gacggtgaca
    14641 tccttgctgt taacgggatc actggagaag tgattatcaa cccaacagat gaacaagcgg
    14701 cagaatttaa agcagctggt gaagcctatg cgaaacaaaa agctgaatgg gcacttttga
    14761 aagatgctca aacagtgact gctgacggta aacacttcga gttggctgcc aatattggta
    14821 ctccaaaaga cgttgaaggt gttaacaaca acggtgcaga agctgttgga ctttaccgta
    14881 cagagttctt gtacatggat tctcaagact tcccaactga agatgagcag tatgaagcat
    14941 acaaggctgt tcttgaagga atgaacggta aacctgttgt cgttcgtaca atggatatcg
    15001 gtggagataa ggaacttcct tacttcgata tgcctcacga aatgaaccca ttccttggat
    15061 tccgtgctct tcgtatctct atctctgaga ctggagatgc tatgttccgc acacaaatcc
    15121 gtgctcttct tcgtgcgtct gttcacggtc aattgcgtat catgttccca atggttgcgc
    15181 tcttgaaaga attccgtgca gcgaaagcag tctttgatga agaaaaagca aaccttcttg
    15241 ctgaaggtgt tgcagttgcg gataacatcc aagttggtat catgatcgag attcctgcag
    15301 cggctatgct tgcagaccaa tttgctaaag aagttgactt cttctcaatt ggtacaaacg
    15361 acttgatcca atatacaatg gcagcagacc gtatgaacga acaagtttca tacctttacc
    15421 aaccatacaa cccatcaatc ctacgcttga ttaacaatgt gatcaaagca gctcacgctg
    15481 aaggtaaatg ggctggtatg tgtggtgaga tggctggtga ccaacaagct gttccacttc
    15541 ttgtcggaat gggcttggat gagttctcta tgtcagcaac atctgtactt cgtacacgca
    15601 gcttgatgaa gaaactcgac acagctaaga tggaagagta cgcaaaccgt gcccttacag
    15661 aatgctcaac aatggaagaa gttcttgaac ttcaaaaaga atacgttaat tttgattaat
    15721 cgaaaagtcc ctgcaactca gttacaggga ctttttttga tattttaaaa agaattttca
    15781 agaaaatctt tcttataaaa agtccaacct tgaaaaagta gtggtcagaa caaaaaatac
    15841 ttaaatggtt cataaaattc ttgacaagtt ggagatttag gagtaaacta ttaaccagtt
    15901 aagtaataga gaggagtttc tgcaatttag aaatgaattg caactagaaa tatcaaatag
    15961 aaagagagtt tcgatgaaaa ttaataagaa ataccttgtt ggttctgcgg cagctttgat
    16021 tttaagtgtt tgttcttacg agttgggact gtatcaagct agaacggtta aggaaaataa
    16081 tcgtgtttcc tatatagatg gaaaacaagc gacgcaaaaa acggagaatt tgactcctga
    16141 tgaggttagc aagcgtgaag gaatcaatgc tgagcaaatc gtcatcaaga taacagacca
    16201 aggctatgtc acttcacatg gcgaccacta tcattattac aatggtaagg ttccttatga
    16261 tgcgattttc agtgaagaat tactcatgaa agatccaaac tataagctaa aagatgagga
    16321 tattgttaat gaggtcaagg gtggatatgt tatcaaggta gatggaaaat actatgttta
    16381 ccttaaggat gctgcccacg cggataacgt ccgtacaaaa gaggaaatca atcgacaaaa
    16441 acaagaacat agtcaacatc gtgaaggtgg gactccaaga aacgatggtg ctgttgcctt
    16501 ggcacgttcg caaggacgct atactacaga tgatggttat atctttaatg cttctgatat
    16561 catagaggat actggtgatg cttatatcgt tcctcatgga gatcattacc attacattcc
    16621 taagaatgag ttatcagcta gcgagttggc tgctgcagaa gccttcctat ctggtcgggg
    16681 aaatctgtca aattcaagaa cctatcgccg acaaaatagc gataacactt caagaacaaa
    16741 ctgg
//
LOCUS       DAVBIC010000049        16417 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.049, whole genome shotgun sequence.
ACCESSION   DAVBIC010000049 DAVBIC010000000
VERSION     DAVBIC010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16417)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16417)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16417
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.049"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            complement(<1..186)
                     /locus_tag="VQ664_001674"
     CDS             complement(<1..186)
                     /locus_tag="VQ664_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2789801.1"
                     /translation="MTIEPGQRIALVGQSGSGKSTLSKILSGLYKIDTGKILFDGVNI
                     NQIDKKILSQNLGVVPQD"
     gene            complement(355..1668)
                     /locus_tag="VQ664_001675"
     CDS             complement(355..1668)
                     /locus_tag="VQ664_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000197307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2789802.1"
                     /translation="MTRKVPNIEQMSQIECGLCCCLSILHFYKSKETLLDLRRDIEKG
                     RDGYSIGDLKQLLNKRNFDTGSYQVKDVNKISELPLPLIAFWDNQHYVVIYKVKKNKV
                     YIMDPSKGYINYEFKEFSKHFSNIVLLSFPNENYQSLKSQFPSPWIRVFSSFSKVKGR
                     LILTLLFSIISYLIILSVPVMTSKFINSALGNTFSFQTSFLILFSLLCLYLISILARS
                     MGILFSNIFFSRDIESFTFKHLLKLPYSFFELRAKGDILYRISSLSGFRELFTNQVVG
                     GVVDIGTILSVVIYMFLSSKTLSIIALILSLINFLFLFSTRKIMYDTVNRELQEQSLI
                     YSVETEALNTISSIKISGLEDEIYENWSKYLKNVLTKYKKRSIVHILYNSATNVFQLF
                     APIIILIFGLDNVLNGKILLGEVVAFQTMASILFSSEISIFNAYT"
     gene            complement(1661..2209)
                     /locus_tag="VQ664_001676"
                     /pseudo
     CDS             complement(1661..2209)
                     /locus_tag="VQ664_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000059560.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(2290..2352)
                     /locus_tag="VQ664_001677"
     CDS             complement(2290..2352)
                     /locus_tag="VQ664_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_128650800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHP2/SHP3 family peptide pheromone"
                     /protein_id="HET2789803.1"
                     /translation="MKKISKFLPILVLVMDIIII"
     gene            complement(2521..3509)
                     /locus_tag="VQ664_001678"
                     /pseudo
     CDS             complement(2521..3509)
                     /locus_tag="VQ664_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050775.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
     gene            complement(3458..4585)
                     /locus_tag="VQ664_001679"
                     /pseudo
     CDS             complement(3458..4585)
                     /locus_tag="VQ664_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423473.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha amylase N-terminal ig-like
                     domain-containing protein"
     gene            complement(4748..5632)
                     /locus_tag="VQ664_001680"
     CDS             complement(4748..5632)
                     /locus_tag="VQ664_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HET2789804.1"
                     /translation="MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVVANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            complement(5744..6598)
                     /locus_tag="VQ664_001681"
     CDS             complement(5744..6598)
                     /locus_tag="VQ664_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HET2789805.1"
                     /translation="MLGAIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGIWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRFYFGGYCR
                     EYEQSINDNLTECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQETVPQAIIAFL
                     ESRDFEDAIRNAISLGGDSDTLAAITCNIAEAAYGIPDWIKDKAYSYLDEPLKDVVRR
                     WENRIKAY"
     gene            complement(6656..7414)
                     /locus_tag="VQ664_001682"
     CDS             complement(6656..7414)
                     /locus_tag="VQ664_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HET2789806.1"
                     /translation="MVVYIRQSKLPSEVSINKYNAQVGAYLQGEEVILYQSFSEIKEL
                     TSEDIVVDYIMETRALLKMMGLNVPVYDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYALS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVVF"
     gene            complement(7476..7664)
                     /locus_tag="VQ664_001683"
     CDS             complement(7476..7664)
                     /locus_tag="VQ664_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HET2789807.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            complement(7986..8552)
                     /locus_tag="VQ664_001684"
     CDS             complement(7986..8552)
                     /locus_tag="VQ664_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789808.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPEENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKTYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            complement(8820..10499)
                     /locus_tag="VQ664_001685"
     CDS             complement(8820..10499)
                     /locus_tag="VQ664_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HET2789809.1"
                     /translation="MSKEKIKVYLYTRVSTSIQIEGYSLEAQKSRMKAFAIYNDYEIV
                     GEYEDAGKSGKSIEGRIQFNRMMEDIKSGKDGVSFVLVFKLSRFARNAADVLSTLQIM
                     QDYGVNLICVEDGIDSSKDAGKLMISVLSAVAEIERENIRIQTMEGRIQKAREGKWNG
                     GFAPYGYKLEDGKLFINEEEAVAIRTIFDQYVNTTIGANGISKYLENHGIRKIPRQNG
                     KNPLFDAGLIRKILKNPVYNGKIAFGRRTLEKVHGTRNEYKQVEQDEYLISEGIHEAI
                     VSDEVWQAAQVKLKSQAKKYEHVNKGKDTRTHLLSGIVKCPICGVGMFGNKCIKKKKD
                     GTKYKDFYYYGCNHRQMIRGHKCTFSKQIREELLDDAVAEVIVKIVSNPKFASMMQEK
                     INMKVDTSEIEKEIDNYQKELRKSHSTKFKLIEEIDNLDVEDKHYKRRKQDLDDRLYR
                     MYDKVDELESSLIDAKAKKQTIEAEKLTGDNIYKVLIYFDKLYKVMNDVERRQLISAL
                     ISEIQVYEEKQSNGQWLKSITFKLPIIEENLNIGLDNDEQVECVSLLEKRS"
     gene            complement(10591..10752)
                     /locus_tag="VQ664_001686"
     CDS             complement(10591..10752)
                     /locus_tag="VQ664_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789810.1"
                     /translation="MDNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQEMKNSFD
                     MAKTQIETD"
     gene            complement(11436..11750)
                     /locus_tag="VQ664_001687"
     CDS             complement(11436..11750)
                     /locus_tag="VQ664_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001835032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789811.1"
                     /translation="MGITWKDIEIDKEREGEIDKKSTPIFYGEFKNVRLSKEEYKNLK
                     EKLNSHTDIMINKLSRYMESSGKTYQNHYVTILKWYEEDKDKLRQKGLNKKMNYDVGE
                     SL"
     gene            complement(11716..12105)
                     /locus_tag="VQ664_001688"
     CDS             complement(11716..12105)
                     /locus_tag="VQ664_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET2789812.1"
                     /translation="MPKRYLLDGKTPRISATNIDNGILGYYEDIDDKNYRVFENFISV
                     SFLGAVFYHKYKASLDMKIHCLKLKNKELNKEVAFYLTSIIRQALKNTEYKDQISSTV
                     LPDIKIKLPIDSRGTPDWNYMERYRDR"
     gene            complement(12493..13287)
                     /locus_tag="VQ664_001689"
     CDS             complement(12493..13287)
                     /locus_tag="VQ664_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2789813.1"
                     /translation="MKGLWSNNLTCGYDEKIILENINIKIPEEKISVIIGSNGCGKST
                     LIKTLSRLIKPLEGEVLLDNKSINSYKEKDLAKHIAILPQSPIIPESITVADLVSRGR
                     FPYRKPFKSLGKDDLEIINRSMVKANVEDLANNLVEELSGGQRQRVWIALALAQDTSI
                     LLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKL
                     VAEGKPEDILNDKLVKDIFNLEAKIIRDPISNSPLMIPIGKHHVSS"
     gene            complement(13287..14294)
                     /locus_tag="VQ664_001690"
     CDS             complement(13287..14294)
                     /locus_tag="VQ664_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HET2789814.1"
                     /translation="MQNLIIGIQKRKNRITLFSSLFLLIIISLSFFILLIGDESYSFS
                     TLIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWSFGLAGFIFQTMLRNPLASPDIIG
                     VTSSSSIAAVFCILVLKTNSLTTGIISITCGLTSSLILFLLAKKDGFSAARLIILGIG
                     FQAVTRAGTSFLLLKVARYELQEVMRWLSGSLSFTKLDDIPLVLIVSIIATILVLFFN
                     KRLEIIELGEEIAIGLGANPELSRLVLIFCAVSLTAFSTSITGPIACISFLAGPIALN
                     IGKKRSPILAGLVGILLVLLSDIFSQNILPARYPVGVVTGLLGSPYLIYLLIKMNRRN
                     I"
     gene            complement(14294..15301)
                     /locus_tag="VQ664_001691"
     CDS             complement(14294..15301)
                     /locus_tag="VQ664_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HET2789815.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLATFG
                     MGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGAS
                     LSVVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
                     ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLN
                     ALAMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISK
                     DIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVN
                     N"
     gene            complement(15291..16316)
                     /locus_tag="VQ664_001692"
     CDS             complement(15291..16316)
                     /locus_tag="VQ664_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HET2789816.1"
                     /translation="MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDH
                     AFGQTILDKKPERVATIAWGNHDVALALGIVPVGFSKANYGVSADKGVLPWTEEKIKE
                     LNGKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQT
                     LWRDMIKIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAAD
                     TSKFWIYTSKDPRANYLTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITY
                     GDDKTLEALQKDPLLGKINAIKNGAVAVIPDNTPLAASCTPTPLSINYTIEEYLNLLG
                     NACKNAK"
BASE COUNT         5145 a         3095 c         2221 g         5956 t
ORIGIN      
        1 atcctgtgga actactccta aattttgact taatattttt ttatctattt gattaatatt
       61 tacaccatca aataaaattt ttcctgtatc aatcttatat aatcctgata gtatttttga
      121 taacgtactt tttcctgacc ccgattgacc gactagtgca attctctgtc ctggctcaat
      181 agtcaaattt aaattttcta ttacaggagc tgagtctttg gaataagaga aagataggtc
      241 cttaatatct attctacctt ctaaagaaca ctttttaaga ccattttcaa cattctcttc
      301 attttcaagc cagatatcat ttactctatt taagtatcct gctgccaaaa tatactacgt
      361 ataagcatta aatattgaga tttctgaact aaataaaatt gatgccatcg tttgaaatgc
      421 gacaacctca cccaataaaa tttttccatt taaaacatta tcaagtccaa aaatcaatat
      481 aattatagga gcgaacaatt gaaatacatt agtagctgaa ttgtataaaa tatgcacaat
      541 acttcgtttt ttatactttg tcaatacgtt ttttaaatac ttagaccagt tttcatatat
      601 ttcatcttct aatcccgata tttttattga agaaatagta tttaatgctt ctgtttctac
      661 tgagtaaatc aatgattgtt cttgtaattc tctattaacc gtatcataca ttatttttct
      721 agtactaaac agaaacaaaa aattgattaa actcaatata agagctataa ttgataatgt
      781 ttttgaacta agaaacatat atattacaac acttagaata gtcccgatat ctactactcc
      841 cccaacaact tggttagtaa atagctccct aaaaccacta agactagaaa ttctgtataa
      901 aatatctcct tttgccctga gttcaaaaaa actatatggt agtttaagca aatgcttaaa
      961 tgtaaaactt tcaatatctc tactaaaaaa tatattagaa aatagaattc ccatactcct
     1021 agccaagata gaaataaggt acaaacaaag tagagaaaat aaaattaaaa acgaggtttg
     1081 aaaagaaaat gtattcccta atgcagaatt aataaacttt gaagtcatta ctggtacgga
     1141 aagtattatt aagtaactta ttattgaaaa tagtaacgtc aaaatcaatc gaccttttac
     1201 ctttgaaaaa ctagagaata ctcttatcca tggagaagga aactgcgact tcaaagattg
     1261 ataattttcg ttaggaaatg atagcagtac tatattacta aaatgttttg aaaactcctt
     1321 aaactcataa tttatatatc ctttagaagg atccattata tagaccttat tcttttttac
     1381 tttgtaaata actacataat gttgattatc ccagaatgct attaatggta acggaagttc
     1441 actaatttta tttacatctt taacttgata tgagccagta tcaaaatttc gtttattcaa
     1501 taactgtttc aagtcaccta tactataacc atctctccct ttttctatat cacgtcttaa
     1561 atctagtaat gtctctttgc ttttatagaa atgtagtatg gacaagcagc aacataaacc
     1621 acattctatt tgagacattt gctcaatatt aggtactttt ctagtcatca tgtcctctta
     1681 actccagtaa taaaacatta agtaatctat catcttgttt tcgagatatt tcatagacaa
     1741 ctccagatac tcctagcata aaagaaaatg tattcatagt attcaaatcc gtacttaatt
     1801 ctggtttgat aacctgagaa acgacattat caaaataaaa atctatagat tcttttatta
     1861 ataggttttc ttcatctttc aatattgcat caagacaact gatagtacct acagaaccgt
     1921 gacataaatt caattctctt attttttcta cattagttaa tacattttca attattgata
     1981 aatcattatt cccaatatta gttttatcga aaatttcttt tctagctaat aaaatgcccg
     2041 gagctccata acaccaaaaa ttaggaaagg aatcattatg atttcttcat atgtctttcc
     2101 aattttttaa tatattattg aaacatttat cttctttata tagtaattcc tctatacatt
     2161 ttaatatatc tgtactagga ttaatttcat aataatatga taattacatt gctactccag
     2221 aataatcgtg tgctaaacct gttactgtta tattatctaa ttgtgaaata caataattaa
     2281 tacacttttt taaatgatga taatatccat caccaaaacc aaaatcggta aaaattttga
     2341 aattttcttc atacttggac ttcctttccg tttttattta ttgtacaata aataaaaacg
     2401 gatttaattt ttgttgggaa aatgggaaat tatgaaatca aaacttggca tcacacttag
     2461 aaaagttcgt aaaggaaaac aaattagtct atgctctgta gcagatgaac atctttcaaa
     2521 atcacaaata tctcgttttg aacgtgggga gtcagagata tcttgtattc gactaatcaa
     2581 tattttagac aaattacata ttactttgta ggggagtttt tggctatcgt tgctcaattg
     2641 tctgattaag gtcctaccct tgatgaaaca attattatcc atgttttctt tattatagac
     2701 aaagtaagaa gacgtttctc gaatgtagac tttatatttt ttatgatttt cttcttccat
     2761 aatatccaat tgatagttgg gaatgaaaat aagaccgctc tgtttgacac cgaaagacac
     2821 cttgatatag acgcccttat caactagctt ctctatttgg ttctctgcaa gttccacttc
     2881 aaattcacga acggtatctc atttttcctt aaatgtctta aaggcttcct caatctcttc
     2941 agtggatact ttatccttat ctcgttcttc ttggaaagca tggtactgtt cctgtaaatt
     3001 ctctaatcct tctgaagcaa cgacttcctt atttttaaaa taatcttgaa aaaatttgac
     3061 atcatataat ttcttatcac ttattttttg atgacccaaa cttatctttt gattattttc
     3121 ttccaggata aaagttacat tttttgtttt aagtcaatgg ttagattcaa ttcttttgct
     3181 tttgttatta aatcttctaa agaattgaca cggtttaaca aaaattctaa acgactttca
     3241 atctcttgct tagcaaaatg cgttctaaaa aattcttcat catatagatc tcgtttgctg
     3301 agttggcgcc ctcgaattgg ttttatcatc gttctatctg tcatcaaaaa acggctatgc
     3361 ttttgactaa aatcaatctg aacatgcaac tgctttgctt tctctaaaaa atcatcaaac
     3421 gatttagatt gctgaagcaa aaaataaaga cgttgtttca attcaaattt atgactagat
     3481 tccttatatt ttttataatc tcgaaaagat caggattttt agctaaaact gccttacgaa
     3541 aatccttcca gaactgatgg tcaatctcat tagccacatc caaacgccaa gcatcgatat
     3601 taaactcttc aatccaataa gtcgcaacct ttaaaagata attcttgacc tctggattgg
     3661 ctgtatttag cttaggcata tagtcctcga aaccaaaaac atgatagggt aagtctctct
     3721 tattaactag cttttcagtt gtcaatggga attgttgaat atggaaccaa tccttataag
     3781 cagactgttc accatttttg acgacatttt ttcattgaag agattgcgaa ccaatatgat
     3841 taaataccgc atccagcatg actttcatgc cacgatgatg cgcttgatcc accagttccc
     3901 gaaaggtctc cttgtctcca aaataacggt caatttcaaa gtaatctgtc gtattgtact
     3961 tgtgattact tgtagattca aagatgggac aaagatatag tccagtaata cccaagtctt
     4021 gcaagtaatt catatgatca ataatcccct gtaaatcacc accaaagaaa tcatcgctct
     4081 taggtgtgac agatgaatcc cagtctaaag tcccttctgg gtttaataga gcattgccat
     4141 tggcaaatct ttcaggaaat atctgatacc ataccgtatt tgaaacccag tcaggaacct
     4201 tgcaggcatc aatctcatga agataaggca acttaaatcc attcccaatt gcatgaagat
     4261 tttctagaga attttccaca caccctttat cgccatacaa aatattttga ccttctgtat
     4321 ctctgagctc aaagagatac tggatacgtg caaagtcaac tgacacttca acctgccaat
     4381 ggtcaaataa ggtaccagaa gttatcttga ccatttcttt tgtatcctga taaaactctt
     4441 ccataaagat aaaagggtcc ccatagtgca agttgatgct ttcaatgtcc cctttcttag
     4501 ttcgaattcg aatatggagt ttcttatcct tataaagata ggcatactcc gactcaggcc
     4561 tatggtaaat agcactcaat tccatcaatt tgtctcctaa agtattcatt caaattttac
     4621 gcaaacgttt tcaaactcaa taaatccagt atactatttt tgtaaactat ttgcaaggaa
     4681 tgtccgttgt taaaggaact atcttttaaa gtatacaaaa agccttaaaa aaggctttct
     4741 ctatatacta atcctctttc ggttttgaaa atacttctac tcgctgagct aggactttga
     4801 tttctacagg taggttatct gatttatctc cgtcaacatc tgactccaat tcactatctg
     4861 aagagatttt aatattacgc gctttgatat actcgatatt atcatttgcg acaacatccc
     4921 cttttaataa atcaggaatg acggataatt tggagaatat agaggcatct ttcagaatca
     4981 aaatgttggc atagccgtcc ttgttttctt caaagatttt cttatcagcg aagtaatttg
     5041 tcaaaaggac caaaacatgg ctagcttcac caacataatt tccattttct gtctcaacct
     5101 taatgttaaa gacctgatct gtcatgacag acttcatggt atttacagca taggttaaaa
     5161 taccgaattt tgttttgtcc tctatttcaa cattgtgaat cgcctcaggc agagaaccga
     5221 tactaaagat ataaccaaaa tagttgtcat ttgctttacc gatatcaatc ttattggtta
     5281 aatcaaaatc cagttcgtca attgcgccat cgatgtcttg attgatttcc aaaagttttg
     5341 taatgaggtt acccgtaccg cctgggataa tccctaactt aggaatgtag tctctctcat
     5401 caatacctga aatgacttca ttgacagttc catctccacc aaacacaacc actgcatcat
     5461 actgctcacg agaagcttct tcagcaaaat gtgttgcatc cagcgctttt tcggtaattt
     5521 tggtttcaac atattcaaag tattcttttg ctttattctc cagcttttct ttgtaatcca
     5581 aagccttctc gccaccagaa gtagggttga taattaccat tgcttttttc attgatttta
     5641 tccttaattt taaacagaaa tgtttacatt tcgtcgtatg caagtaaatg taatcctatt
     5701 atacaatgaa aatacagaaa agagaaatct gacgtactgg agattaatac gcttttattc
     5761 tattttccca tcgcctaact acatccttta agggttcatc caagtaagaa taggccttat
     5821 ccttgatcca atcaggaata ccgtaagctg cctctgctat gttacaagtg attgctgcga
     5881 gagtatcact gtcgccacca agtgagatgg catttcttat cgcatcttcg aagtctctac
     5941 tttcaagaaa ggcgataatg gcttgaggga cagtttcctg acatgtttcg ttaaaacgat
     6001 agttaggacg gatttcatct aaagtttgag atagattgta atcgtattct ttttctatat
     6061 aatccttaat tcgtctttta cactctgtaa gattgtcgtt aattgattgc tcgtactctc
     6121 tacaataacc accaaagtaa aaacgacata gaaagatagc atcagctgta gccatagcgc
     6181 ctttgacacc ttctggatga ttatgagtta cctctgcaga aagactcgta agtcctctag
     6241 atgatggcca tataccagtt ttcgcataaa aaccacagtc catgatccaa gcacatggag
     6301 aaatacgcat agctgatcca ttcccaaagc tattataagg ctcacggtta tcgctgttta
     6361 gccatgcatt aaaccgagca ccgtaatcag cattcggata cattctgcca tatttcttca
     6421 tcgcgtcaat gaaatcgtct ttttgtccac cattcataat tgcttctgca acagcacagg
     6481 tcataaccgt gtcatctgta aaaaagcagt ccttccgaaa taaaggaaag tcctttgttt
     6541 tgatattgtt ccattcgtaa acagaaccga caatatctcc aataattgct ccaagcatca
     6601 gattcctcct tgttcatttt gatgcttttt atattggtta tataccatat ttattttaga
     6661 aaacaacatc ctgttggatt ttaaaaattt catttttttc aaaatagggt tttaccattt
     6721 ctttccacct agctctatga aaattgattg attttaaagg agatagggca taatttccca
     6781 atgcataacc atcatttact tcaacaacaa gtgttctgcc atcgcgagta acaccgatat
     6841 ctagtccata agctattggc gcatctttcc aacatgatat cgcttcatca attacacttg
     6901 catcaaattg tgcatgataa tcacctgtat agggtcgaac atctaatacg cgaccatcta
     6961 acacaaaaca acgccattca gctatgaatt ctacaacctc actaatccat ataggatagt
     7021 cgaaaggtag accaatacct attaaatcat gggttccatt aacaactctt ccagtaaaga
     7081 cttttgaacc agctttaggc ttaataaatt ttccccaatt atcaggtata ttcacaatct
     7141 ctcctaaaat accagcataa atctttcgac cataaaactc tttaagctca ataggatagt
     7201 cataaaccgg aacgtttaag cccatcattt ttagtaatgc tctagtctcc attatataat
     7261 ctacaactat atcttcactt gttaactctt ttatttcaga aaaagattga tataaaataa
     7321 cttcttctcc ttgtaagtag gcacctactt gagcattgta tttattaatt gaaacctcac
     7381 ttggtaattt actttgtcta atataaacaa ccatttcatc actcctatat cactagtgtt
     7441 acactgattt gtaaaaaata atagcaattt tgctcttatt tttttgagta aatagctccc
     7501 ataatatcat cgaaataatc aacggtattt aggagtaatt caataacctg ggactttgtt
     7561 agtcgcattc cccttctatc tctagcatct tctactaaat tttcaagttt ctctagattt
     7621 ttatcatcca agctaatcat tattctattt ttatcggttg ccattttcat cacctcaagt
     7681 taattctatc acaggtgtaa cacttgtgtc aactggcttt tataatacat tagtttaaaa
     7741 gtggagagga tttttaacac agtaacttta aatctttggt attaaaaaat tttcacaata
     7801 tttatagaaa taaaatctgt ctcaaatcag ttatcaaatc tagtataaat tatgagcggc
     7861 tactctaata ctttccctct aaacaagaaa aagacttaca ctcaaggatt ttcttccccc
     7921 ccttcgttat aacgttttga ctcttttact agcaaaggta tatactcaca aggaactttg
     7981 gttgactatt gaatctctcc aacttcttct ttaacatatc cttctacatc ttcaatctct
     8041 acaaacattg ggtctaagtg acacaagaaa tgccaaactt cgatcccttt ttttctgtaa
     8101 agaatcgctt caccgtcttc acttccgaaa aagcttctgt cgatttcata tccgcggctt
     8161 tctaagaagt cttttgcttt acgatagttc gtttctcttg tttcgacata ggttttaact
     8221 tcatggttgt taacgacata tgcatcaatt tttgaatatc cttcgatcac tctatcattt
     8281 ttgagggata aatttgaaat ctctttccaa ataatgttta cattttcctc aggatcgaac
     8341 ataaatttag ataaaggaac aatatttccg ttaaaaataa tttccatata atccggtatg
     8401 tttttaggat taaaatactc cacttcaaaa ccatcttctg tttccagagt gtatcccggg
     8461 atttgagcta caaaggcttt cccatcttct atggaatcaa atgctactaa atctttagaa
     8521 taatcatttt ggtacaattc caatataacc atcgataatc tctccatttt cattatcagg
     8581 ctaatgtaaa taagcacgtc acctgaccaa ttcaggctct ctgtatcatc tcatcatatt
     8641 tcctacttac tttacgagtc ctatacccag aacacacctt atcgaccttc ggtctcacct
     8701 cgttgcattg gctgaacatc tacttttact tcgctgatgc ttcaactcgt acaagcagtg
     8761 ataccgcctc agcgtgatgc gtcagtggga ctcaaaaggt tcggggaacc ttttgaggat
     8821 taactacgtt tctctaataa acttacacat tcaacttgtt catcattgtc caaacctatg
     8881 ttgagatttt cttctataat tggtagctta aaagtaatgg attttagcca ttgtccgtta
     8941 gattgttttt cttcataaac ttgaatttca gaaatcaaag ctgaaattaa ctgcctacgc
     9001 tctacatcat tcatgacttt atagagctta tcaaaataga tcagaacctt atatatgtta
     9061 tctcctgtaa gcttttcagc ttcaatagtc tgtttctttg ctttcgcatc aattagtgat
     9121 gattctaatt catctacttt gtcatacata cgatatagtc tatcatctaa atcctgtttc
     9181 cttctcttat aatgcttatc ttcaacatct aaattatcta tttcctcaat tagcttaaac
     9241 tttgtagaat gactctttct caattccttt tggtaattat ctatttcttt ttctatttca
     9301 gaggtatcca ccttcatgtt gattttttct tgcatcatag aagcaaattt cggattactt
     9361 actatcttga caatcacctc tgcaacagca tcatctaaca attcttctct aatttgctta
     9421 ctgaatgtac acttatgacc tcttatcatc tgcctatggt tacaaccata gtaataaaaa
     9481 tctttatact ttgtgccatc tttctttttc ttgatacact tgttcccaaa cattcccact
     9541 ccacatatcg ggcattttac aattccagaa agcaagtgtg tgcgtgtatc ttttccttta
     9601 ttcacatgct catatttctt tgcttgagat tttagcttaa cctgagcagc ttgccaaact
     9661 tcatcggaaa ctatagcttc atgtatccct tcagatatta gatattcatc ttgttcaacc
     9721 tgcttatatt catttcttgt accatgaact ttttctaaag ttcttcttcc aaatgctatt
     9781 ttcccattat atacaggatt ctttaatatc tttcttataa gacctgcatc aaacaaagga
     9841 ttcttaccat tctgtcttgg gatttttcta attccatgat tctctaagta tttagatatc
     9901 ccattggctc ctatcgtagt atttacatac tggtcgaaaa tcgttcttat tgcaactgcc
     9961 tcttcctcat ttataaacag cttgccgtct tcaagtttat atccatacgg agcaaagcca
    10021 ccattccatt ttccttccct tgctttttga atgcgacctt ccattgtttg aatacggatg
    10081 ttttctcttt ctatttcagc cacagctgat aaaacagaaa tcattagttt cccagcatct
    10141 ttagatgaat caatgccatc ttcaacgcag ataagattaa ctccataatc ctgcattatc
    10201 tgaagtgtag aaagaacatc agcggcattt cttgcaaatc ttgataactt aaacacaaga
    10261 acaaaagata ctccatcttt tccagatttt atatcttcca tcattcgatt gaactgtatt
    10321 ctaccttcaa tagacttgcc agacttcccg gcatcttcat actctccaac aatttcataa
    10381 tcgttgtaaa tagcaaaagc tttcattcgt gatttttgtg cctctaacga atacccctct
    10441 atctgtattg acgtagatac tcgtgtatag aggtatactt ttattttttc ttttgacata
    10501 gtattaatct caatataatt tttctatatc atatataatt tttttaattt aagtttggac
    10561 tatcatttca agtatattat aacactttta ttagtccgtc tcaatttgtg tttttgccat
    10621 gtcaaaacta tttttcatct cttgattttt tgctggcgtt ggatcgggta gattatctaa
    10681 atctaaagca ccagcatatt ttgcaatcag atttgctatt aaatcagcca atccattcca
    10741 gtcattgtcc aatatatacc tcctctaaag ttttatatct aataattatt tgtttaatta
    10801 agttttttga cattgacaag tgctttggat tagcaacata ggaatctcac ctccgcctct
    10861 attccggatg agccggcttc aaccttagaa gtatcattat cctcattttc ttcatagcgg
    10921 atagggtatc cctccctata ttcaaactct tacttatcgc tcactttctt tttacttagc
    10981 agaacttttt ttgccgaatt attcagccga aagatcttga cggataggtt attacgctcc
    11041 aaaaataatt aacgtcttgt cttggtctat tcaattgtta aggttcaaaa tttatcgaga
    11101 gttattaatc tttttaaaat ttgaccatca gaaaatattt atcttaatgt aacaaaattc
    11161 tataaattac cctcttatac ttaacagtga aaagaagtct ttcttggtaa ccaattttga
    11221 aatagaattt gcttatataa aaaggtcaaa ttcccactgc ataagtagca gtgaaaatta
    11281 gaccctcttg gtaactgtca tctaaaagtc ttctagcatt tctttaattt tctaatcgcc
    11341 tttaaagtgt catatttata tttttttatc tctggcatac tttgatacct ttttagactt
    11401 aaagtcttta atagtgcctt tccacctctt tttatctata aagattctcc tacatcataa
    11461 ttcatttttt tatttaaacc tttctgtctt agtttgtctt tatcttcttc ataccatttt
    11521 aagattgtca catagtggtt ttgataggtc ttaccactgc tttccatgta tctggatagt
    11581 ttatttatca ttatatctgt gtgtgagttt aatttttctt ttagattttt atattcttct
    11641 ttgcttaacc ttacattttt gaattctcca taaaaaatgg gggtggactt tttatctatc
    11701 tctccctctc tctctttatc tatctctata tctttccatg taattccaat ctggagtacc
    11761 tctactgtct atcggtaatt taattttgat atctggcaat actgtgctag atatttgatc
    11821 tttatattca gtatttttta aagcttgcct aataattgaa gttaaataga atgctacttc
    11881 tttattcaat tctttatttt ttaattttaa acaatgaatt ttcatatcta ggcttgcttt
    11941 atatttatga taaaagactg ctcctaaaaa tgaaacagat ataaaatttt caaaaactct
    12001 ataattttta tcatctatat cttcgtagta acctaagata ccattgtcaa tatttgtagc
    12061 actaattcta ggagtttttc catcgagtaa atatcttttt ggaatagatg agcctgttgg
    12121 tacttgactc gatttcccct ttttttcggt aataaatatt tctttttatt ttgttgtctg
    12181 atatttttcc tacctgtcct ttgtaggatg agtattttct agattttctt gaataacttt
    12241 ttacttgaag ttttagcttt tgaactagtc gttgtacttt ctttttgttt attatcagtc
    12301 ctgatctttt taatattgct gttattctct atatcctatt tttcattcat gatattcttt
    12361 tactaatttt atcttaaatt ctgtgctgta tttgccatta aaaaactgac ctcctttagt
    12421 tagttttttg gcctaacttt tgagggtcag ttcaaaattt gcgactttta aatgaattcc
    12481 aatattcaat tattaagagc taacatggtg cttgccaata ggaatcatta gaggcgaatt
    12541 ggaaataggg tcacgtataa tttttgcttc aagattaaag atatctttaa ctagtttatc
    12601 atttagtata tcttcaggct ttccctctgc aacaagttta ccttctttaa ttgcaaatag
    12661 gtaatcagcg tatcttgctg ttagatttat atcgtgcaaa atcatgcaaa tggttgtctt
    12721 atatttttgg tttagatcag tcaagaggtc taatagttct atttgatatg agatatccaa
    12781 gtaagtagtt ggctcatcta aaagtaggat acttgtatct tgggctaggg ctagagctat
    12841 ccatactctt tgcctttgac ccccagaaag ttcttcaact aggttatttg ctagatcttc
    12901 aacattggcc ttaaccattg atctgtttat tatttcaagg tcatcttttc caagactctt
    12961 aaaaggcttt ctgtagggga aacgaccacg gcttacaaga tcagctactg ttattgattc
    13021 agggattatt ggagattgag gtaatatagc tatgtgtttt gctaaatctt tttctttata
    13081 agaattaatt gatttattat caagcaatac ttctccctct aatggcttta taagtcgaga
    13141 caaggtttta atgagtgttg atttcccaca accatttgac ccaataataa ctgatatttt
    13201 ttcttcaggt atttttatat ttatattttc caagattatt ttttcatcat aaccgcaggt
    13261 aagattattt gaccacagac ctttcattat atattcctcc tgttcatttt tattagtaag
    13321 tatattaagt atggtgaacc taacaagcca gttacaacac ctactggata tctagctggt
    13381 aaaatatttt gagagaatat gtctgataac aaaactagta aaattccaac caatccagct
    13441 aatattgggc ttcttttctt gccaatattt aaggctatgg gaccagctaa aaaagatata
    13501 caagctattg gtcctgtaat tgaagtagaa aaagcagtta aagatacagc gcaaaaaatt
    13561 aaaacaagcc ttgaaagctc gggatttgct ccaagtccga ttgctatttc ttcaccaagt
    13621 tcaataattt ctagtctttt attaaaaaat aaaactaata tagtagcaat aatacttact
    13681 attagaacaa gaggtatgtc atctaacttt gtaaaagata aagagccact gagccatctc
    13741 ataacttctt gtaattcata tcttgctact ttcaacaata aaaatgaggt gcctgctctt
    13801 gtgacagctt gaaaaccaat acctaatatt atcagtcttg ctgctgaaaa accatctttt
    13861 ttagctagta aaaataatat taaagatgat gttagtccac aagttattga aataattcca
    13921 gtagttaaac tatttgtttt taataccaat atgcaaaaga ccgctgcaat agatgaagaa
    13981 cttgtgacac cgattatatc aggacttgca agaggatttc ttaacatagt ttgaaagata
    14041 aatcctgcca atccaaaaga ccagccagct ataattcctg ctaataattt tggtaatcta
    14101 atttccataa tcgaaaaact agctccagga acagtttcac tatttaagac tttaatcaaa
    14161 gttgaaaaag aataactttc atctccgata agtaaaatga aaaatgatag actgattatt
    14221 attaataaaa atagtgagga aaatagtgtt attctatttt ttcttttttg aatacctata
    14281 attaaatttt gcattagtta ttaacccctc tatttttcat agttacataa ataagtactg
    14341 gacccccgat tattgcagta attatcccta cttcaatttc acctggttta cctaacatac
    14401 ggccgattat atcacatata agcaagagct ctgcacctat aaaagatgaa gaaatggtca
    14461 ttgtgcgtat atctttgctt ataaataagc cacaaaagtg aggaactata agacctacga
    14521 agccaatagg tccaccaatt gcagtaatac ttgaacataa aagcacactt gcaattattg
    14581 caagtgatct tatcctatta acattaactc caagaccaac agccatttca tcacccatag
    14641 ctaaagcgtt taaatctgat gaaataaata tagctatcaa gtgacctaaa attataaaag
    14701 gtagtagtgt agatatagaa gataatgtag ctgctccaag gctacctatt tgccaaaatc
    14761 taaatttgtc taagacgtta ttattcggta aaattaaaaa acttacaaaa ctgcttaaag
    14821 ccatactaac acaagttcct gataaggcta gttttatagg ggtaaggcct gcttttccgc
    14881 ttacagcaat cgcgtataca aaaattgcac ttactaagcc accaatgatt gcaaaactta
    14941 tatggcttat gcttgatgaa attcctaaaa aagaaagacc aattactaca ctaagacttg
    15001 ctcctgtgtt tataccgagt atacctggat cagctattgg gtttctagta actgattgca
    15061 tcaatacacc gcttatggca agactagaac ctgctaaaat tgcaaaaata gttctaggta
    15121 ttcttttata tataattgat ttaataaaat catcatttgt attgcccatt ccaaaagttg
    15181 ctaaaaaatc tctgatatta atttcttttg ttccaagctt taatgacaaa aatattgtaa
    15241 taagaagacc taggcagatt acaaaaatta tgcctaggtt tatttgtttt ttatttcgca
    15301 tttttgcatg catttcctaa aagatttagg tattcttcaa tagtatagtt tattgaaagt
    15361 ggtgttggag tgcatgaggc tgctaacggt gtattatctg gaattacagc aacggcacca
    15421 tttttaattg catttatttt acctaaaaga ggatcttttt gtaaagcttc aagagtttta
    15481 tcatcaccat aagttatgat tacatcagca tcatttatct tatttgcttc ttctgcagaa
    15541 atttcctttg caaaactatc ttcactctca aattctttta atgattcagg gaaaactaga
    15601 cctaaatctg ttaaataatt tgctcttgga tctttgctag tataaatcca gaattttgat
    15661 gtatctgcag cattaatcat agtaaataat actttttttc ctttgatttt tcctttgatt
    15721 tctggatgtt tttctaattc tttggatata cgagcttcag tatttttgat taactcatca
    15781 ccttcttttt ccatacctaa ggcttttgaa tcaattttaa tcatatctct ccataaagtt
    15841 tgccaaggtt tagatttgta tgctgctaca ggagcaattt ttgatagagt gtcataatct
    15901 tctttagtta taccagaata acctgctaag ataacatctg gtttagaatt tgatattgct
    15961 tcaaagttaa gtccatccaa atcgtcaaat aggttagctt taccatttag ttctttgatt
    16021 ttttcttctg tccatggtaa aactccttta tcagcactta caccgtaatt tgcttttgaa
    16081 aatccaacag gaactattcc taaagctaat gctacatcat gatttcccca agcaatagtt
    16141 gcaactcttt caggtttttt atctaatata gtttgaccga aagcatgatc taaaactatt
    16201 ttatcaggcg catgctcttt agaagtattt tcttcatttt taacagaatt agaagaacaa
    16261 gcgctaaaaa ctatacacat agctaaaata gctattagaa aaaatttgtt tttcataaaa
    16321 actccttaaa catatttcaa gtctattgta tcgataataa ttatcattgt caatagatac
    16381 agttacaaat ttaataatat aattttttca aaaaagg
//
LOCUS       DAVBIC010000050        16132 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.050, whole genome shotgun sequence.
ACCESSION   DAVBIC010000050 DAVBIC010000000
VERSION     DAVBIC010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16132)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16132)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16132
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.050"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            145..6831
                     /locus_tag="VQ664_001693"
     CDS             145..6831
                     /locus_tag="VQ664_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HET2789817.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTVEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKPEEKAPRIESQTSNQEKPLKEDAKAVTNEEVNQMIEDRKVDFNQNWYF
                     KLNANSKEAIKPDVDVSTWKKLDLPYDWSIFNDFDHESPAQNEGGQLNGGEAWYRKTF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLHKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIVNTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLATVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKALRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGFKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SNQVTVFTGKKEGQEKTVLGTEVARVRTLIGKEPKMPKTVGFVYSDGSREKLPVTWSQ
                     VDVSQAGVVTVKGTANGREVEAHVEVLAIAKELPTVKRIAPNTDLNSVDKSVSYVLTD
                     GSVQEYEVDSWEITEVDKAKLSVAGSRIQMTGQLAGETIHATLVVEEGNAAAPVVPTV
                     TVGGEAVTGLTSRQPMQYRTLSYGAQLPEVTASAENADVTVLQASAANGMRASIFIQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLKAEYEGAKGQVELTIQANTEKKIAQSIRP
                     VNVVTDLHQKPTLPTTVTVEYDKGFPKAHKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARAKVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRIEQYA
                     KEGVFTVNGRLEDTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRTNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     APKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAQLKAGEMNHF
                     SFDKVETYAVRIRMVKADNKRGTSITEVQIFAKQVAAAKQGQIRIQVDGKDLANFNPD
                     LTDYYLESVDGKVPAVTASVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKNLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDGYETKDLTVEWEEVPAEN
                     LTKAGQFTVRGHVLGSDLVAEVTVRVTDKLGEALSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVAQAKLRFFA
                     DSGTDAPTKLVLERYVGPEFEVPTYYSNYQAYDADHPFNNPENWEAVPYRADKDIAAG
                     DEINVTFKAVKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSLPVLVRLVSESGKQVKEYR
                     IQLTKEKPVSAVQEDLPKLEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKTGKERIFT
                     AINPDGSKEEKLREVVEAPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSEASQTN
                     KAQLPNTGSAASQAAVAAGLALLGLSAGLVVTKGKKED"
     gene            complement(7079..7935)
                     /locus_tag="VQ664_001694"
                     /pseudo
     CDS             complement(7079..7935)
                     /locus_tag="VQ664_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270419.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(8146..8505)
                     /locus_tag="VQ664_001695"
     CDS             complement(8146..8505)
                     /locus_tag="VQ664_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HET2789818.1"
                     /translation="MGMILMKLASILLLILTLVVCIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLALSILAIILVFFFLLKKRSFYYPKFIKFFWRAGFL
                     LTLIMYIEMIVELFLMK"
     gene            8597..9553
                     /locus_tag="VQ664_001696"
                     /pseudo
     CDS             8597..9553
                     /locus_tag="VQ664_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002881980.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein.; internal stop;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
     gene            9537..10094
                     /locus_tag="VQ664_001697"
     CDS             9537..10094
                     /locus_tag="VQ664_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET2789819.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALEKTQERLHQADLTNAQLILQGHETLDQFVIKAKAGIFNLGYLPSADKSV
                     ITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            10087..10341
                     /locus_tag="VQ664_001698"
     CDS             10087..10341
                     /locus_tag="VQ664_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789820.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTHHERSVGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            10353..12407
                     /locus_tag="VQ664_001699"
     CDS             10353..12407
                     /locus_tag="VQ664_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HET2789821.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLPLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKDKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETAIISSGAFVERVINRVKPNNID
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            12586..13446
                     /locus_tag="VQ664_001700"
     CDS             12586..13446
                     /locus_tag="VQ664_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HET2789822.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLCFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSMNFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQLLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNLSNRKISYTLPGSAFV
                     LLVILGLLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLKDPVFKKD"
     gene            13657..14367
                     /gene="ccdA2"
                     /locus_tag="VQ664_001701"
     CDS             13657..14367
                     /gene="ccdA2"
                     /locus_tag="VQ664_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HET2789823.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGLLVLFGNASILSQLFE"
     gene            14387..14953
                     /locus_tag="VQ664_001702"
     CDS             14387..14953
                     /locus_tag="VQ664_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HET2789824.1"
                     /translation="MKKWQTCVLGAGSLLCLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            14964..16076
                     /gene="msrB"
                     /locus_tag="VQ664_001703"
     CDS             14964..16076
                     /gene="msrB"
                     /locus_tag="VQ664_001703"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HET2789825.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKAVKKTEISKDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
BASE COUNT         4901 a         3052 c         3565 g         4614 t
ORIGIN      
        1 catatctacg gcaaggcgac actgacgaag tttgaattgg attttcgcag agtgtaaatt
       61 gttgaaacta ggttgtcata ccatgtatac cacttgggct ttggtagtag ctaactgcac
      121 taaatataat ataaggaggg ttttatgggg aaaggccatt ggaatcggaa aagagtttat
      181 agcattcgta agtttgctgt gggagcttgc tcagtaatga ttgggacttg tgcagttcta
      241 ttaggaggaa atatagctgg agaatctgta gtttatgcgg atgaaacact tattactcat
      301 actgttgaga aacctaaaga ggaaaaaatg atagtagaag aaaaggctga taaagctttg
      361 gaaactaaaa atgtagttga aaggacagaa caaagtgaac ctagttcaac tgaggctatt
      421 gcatctgaga agaaagaaga tgaagccgta actccaaaag aggaaaaagt gtctgctaaa
      481 ccggaagaaa aagctccaag gatagaatca caaacttcaa atcaagaaaa accgctcaag
      541 gaagatgcta aagctgtaac aaatgaagaa gtgaatcaaa tgattgaaga caggaaagtg
      601 gattttaatc aaaattggta ttttaaactc aatgcaaatt ctaaggaagc cattaaacct
      661 gatgtagacg tatctacgtg gaaaaaatta gatttaccgt atgactggag tatctttaac
      721 gatttcgatc atgaatctcc tgcacaaaat gaaggtggac agctcaacgg tggggaagct
      781 tggtatcgca agactttcaa actagatgaa aaagacctca agaaaaatgt tcgccttact
      841 tttgatggcg tctacatgga ttctcaagtt tatgtcaatg gtcagttagt ggggcattat
      901 ccaaatggtt ataaccagtt ctcatatgat atcaccaaat accttcacaa agatggtcgt
      961 gagaatgtga ttgctgtcca tgcagtcaac aaacagccaa gtagccgttg gtattcagga
     1021 agtggtatct atcgtgatgt gactttacaa gtgacagata aggtgcatgt tgagaaaaat
     1081 gggacaacta ttttaacacc aaaacttgaa gaacaacaac atggcaaggt tgaaactcat
     1141 gtgaccagca aaatcgtcaa tacggacgac aaagaccatg aacttgtagc cgaatatcaa
     1201 atcgttgaac gaggtggtca tgctgtaaca ggcttagttc gtacagcgag tcgtacctta
     1261 aaagcacatg aatcaacaag cctagatgcg attttagaag ttgaaagacc aaaactctgg
     1321 accgttttaa atgacaaacc tgccttgtac gaattgatta cgcgtgttta ccgtgacggt
     1381 caattggttg atgctaagaa ggatttgttt ggttaccgtt actatcactg gactccaaat
     1441 gaaggtttct ctttgaatgg tgaacgtatt aaattccatg gagtatcctt gcaccacgac
     1501 catggggcgc ttggagcaga agaaaactat aaagcagaat atcgccgtct caaacaaatg
     1561 aaggagatgg gagttaactc catccgtaca acccacaacc ctgctagtga gcaaaccttg
     1621 caaatcgcag cagaactagg tttactcgtt caggaagagg cctttgatac ttggtatggt
     1681 ggcaagaaac cttatgacta tggacgtttc tttgaaaaag atgccactca cccagaagct
     1741 cgaaaaggtg aaaaatggtc tgattttgac ctacgtacca tggtcgaaag aggcaaaaac
     1801 aaccctgcta tcttcatgtg gtcaattggt aatgaaatag gtgaagctaa tggtgatgcc
     1861 cactctttag caactgttaa acgtttggtc aaggttatca aggatgttga taagactcgc
     1921 tatgttacca tgggagcaga taaattccgt ttcggtaatg gtagcggagg gcatgagaaa
     1981 attgctgatg aactcgatgc tgttggattt aactattctg aagataatta caaagccctt
     2041 agagctaagc atccaaaatg gttgatttac ggttcagaaa catcttcagc tacccgtaca
     2101 cgtggaagtt actatcgccc tgaacgtgaa ttgaaacata gcaatggacc tgagcgtaat
     2161 tatgaacagt ctgactatgg aaatgatcgt gtgggttggg ggaaaacagc aaccgcttca
     2221 tggacttttg accgtgacaa cgctggctat gctggacagt ttatctggac aggtacggac
     2281 tatattggtg aacctacacc atggcacaac caaaatcaaa ctcctgttaa gagctcttac
     2341 tttggtatcg tagatacagc cggcattcca aaacatgact tctatctcta ccaaagccaa
     2401 tgggtttctg ttaagaagaa accgatggta caccttcttc ctcactggaa ctgggaaaac
     2461 aaagaattag catccaaagt agctgactca gaaggtaaga ttccagttcg tgcttattcg
     2521 aatgcttcta gtgtagaatt attcttgaat ggaaaatctc ttggttttaa gactttcaat
     2581 aaaaaacaaa ccagcgatgg gcggacttac caagaaggtg caaatgctaa tgaactttat
     2641 cttgaatgga aagttgccta tcaaccgggt accttggaag caattgctcg tgatgaatct
     2701 ggcaaggaaa ttgctcgaga taagattacg actgctggta agccagcggc agttcgtctt
     2761 attaaggaag accatgcgat tgcagcagat ggaaaagact tgacttacat ctactatgaa
     2821 attgttgaca gccaggggaa tgtggttcca actgctaata atctggttcg cttccaattg
     2881 catggccaag gtcaactggt cggtgtagat aacggagaac aagccagccg tgaacgctat
     2941 aaggcgcaag cagatggttc ttggattcgt aaagcattta atggtaaagg tgttgccatt
     3001 gtcaaatcaa ctgaacaagc agggaaattc accctgactg cccactctga tctcttgaaa
     3061 tcgaaccaag tcactgtctt tactggtaaa aaagaaggac aagagaagac tgttttgggg
     3121 acagaagtag caagagttcg tacattaatt ggtaaagaac caaaaatgcc gaaaacagta
     3181 ggttttgtat acagcgatgg tagtcgtgaa aaacttccag taacttggtc tcaagtcgat
     3241 gttagtcaag caggagttgt gactgttaaa ggtacagcaa atggacgtga ggtagaggct
     3301 catgtcgagg ttctagcaat tgcgaaagaa ttaccaacag ttaaacgtat tgctccaaat
     3361 actgacttga attctgtaga caaatctgtt tcttatgttt tgactgatgg aagtgtacaa
     3421 gagtacgaag tagatagctg ggagattacg gaagtagata aagccaaact ttcagtagct
     3481 ggatcacgta ttcaaatgac tggtcagtta gctggagaaa ctattcatgc aacccttgtg
     3541 gtagaagaag gaaatgctgc agcacctgta gtgccaactg ttactgttgg aggtgaggca
     3601 gtaacaggtc ttactagtcg acaaccaatg caatatcgta ctctatctta tggtgcccaa
     3661 ctgccagaag tcacagcaag tgctgaaaat gctgatgtga cagttcttca agcaagcgca
     3721 gcaaacggca tgcgtgcgag catctttatt cagcctaaag atggtggtcc tcttcaaacc
     3781 tatgcaattc aattcctaga agaagcacca aaaattgctc acttgagttt gcaagtggaa
     3841 aaagctgaca gtctcaaaga agaccaaact gtcaaattgt cggttcgagc tcactatcaa
     3901 gatggaacgc aagctgtatt accagctgac aaagtaacct tctctacaag tggtgaaggg
     3961 gaagtcgcaa ttcgtaaagg aatgcttgag ttgcataagc caggagcagt cactctcaaa
     4021 gcggaatatg agggagctaa aggccaagtt gaactcacta tccaagccaa tactgagaag
     4081 aagattgcgc aatctatccg tcctgtaaat gtagtcacag atttgcatca aaaacctact
     4141 cttccaacaa cagtaacggt tgagtatgac aaaggtttcc ctaaagctca caaagtcact
     4201 tggcaagcta ttccgaaaga aaaactagac tcctatcaaa catttgaagt actaggtaaa
     4261 gttgaaggaa ttgaccttga agcgcgtgca aaagtctctg tagaaggtat cgtttcagtt
     4321 gaagaagtca gtgtgacaac tccaatcgca gaagcaccac aattaccaga aagcgttcgg
     4381 acatatgatt caaatggtca cgtttcatca gctaaggttg catgggatgc gattcgtata
     4441 gagcaatacg ctaaggaagg tgtctttaca gttaatggtc gcttagaaga tactcaatta
     4501 acaactaaac ttcatgttcg cgtatctgct caaactgagc aaggtgcaaa catttctgac
     4561 caatggaccg gttcagaatt gccacttgcc tttgcttcag attcaaatcc aagcgaccca
     4621 gtttcaaatg ttaatgacaa gctcatttcc tacaataacc aaccagccaa tcgttggaca
     4681 aactggaatc gtactaatcc agaagcttca gtcggtgttc tgtttggaga ttcaggtatc
     4741 ttgagcaaac gctccgttga taatctaagt gtcggattcc acgaagacca tggagttggt
     4801 gcaccgaagt cttatgtgat tgagtattat gttggtaaga ctgtcccaac agctcctaaa
     4861 aaccctagtt ttgttggtaa tgaggaccat gtctttaatg attctgccaa ctggaaacca
     4921 gttactaatc taaaagcccc tgctcaactc aaggctggag aaatgaacca ctttagcttt
     4981 gataaagttg aaacctatgc tgttcgtatt cgcatggtta aagcagataa caagcgtgga
     5041 acgtctatca cagaggtaca aatctttgcg aaacaagttg cggcagccaa acaaggacaa
     5101 ataagaatcc aagttgacgg caaagactta gcaaacttca accctgattt gacagactac
     5161 taccttgagt ctgtagatgg aaaagttccg gcagtcacag caagtgttag caacaatggt
     5221 ctcgctaccg tcgttccaag cgttcgtgaa ggtgagccag ttcgtgtcat cgcgaaagct
     5281 gaaaatggcg acatcttagg agaataccgt ctgcacttca ctaaggataa gaacttactt
     5341 tctcataaac cagttgctgc ggttaaacaa gctcgcttgc tacaagtagg tcaagcactt
     5401 gaattgccga ctaaggttcc agtttacttc acaggtaaag acggctacga aacaaaagac
     5461 ctgacagttg aatgggaaga agttccagca gaaaatctga caaaagcagg tcaatttacc
     5521 gttcgaggcc atgtccttgg tagtgatctt gttgctgagg tcactgtacg agtgacagac
     5581 aaactaggcg aagctctttc agataaccct aactatgatg aaaacagtaa ccaggccttt
     5641 gcttcagcaa ccaatgatat tgacaaaaac tctcatgacc gcgttgacta tctcaatgac
     5701 ggagatcatt cagaaaatcg tcgttggaca aactggtctc caacaccatc ttctaatcca
     5761 gaagtatcag cgggtgtgat cttccgtgaa aatggtaaga ttgtagaacg gactgttgcc
     5821 caagccaaac ttcgtttctt tgcagatagt ggtacggatg caccaactaa actcgtttta
     5881 gaacgctatg tcggtccaga gtttgaagtg ccaacctact attcaaacta ccaagcctac
     5941 gacgcagacc atccattcaa caatccagaa aattgggaag ctgtgcctta tcgtgcggat
     6001 aaagacatcg cagctggtga tgaaatcaac gtaacattta aagctgtcaa agccaaagct
     6061 atgagatggc gtatggagcg taaagctgac aagagcggtg ttgcgatgat tgagatgacc
     6121 ttccttgcac cgagtgaatt gcctcaagaa agtacgcaat cgaagattct tgtagatgga
     6181 aaagaacttg ctgatttcgc tgaaaatcgt caagactatc aaattaccta taaaggtcaa
     6241 cggccaaaag tctcagttga agaaaacaat caagtagctt caactgtggt agatagtgga
     6301 gaagatagcc ttccagtact tgttcgcctc gtttcagaaa gtggaaaaca agtcaaggaa
     6361 taccgtatcc agttgactaa ggaaaaacca gtttctgctg tacaagaaga tcttccaaaa
     6421 ctcgaatttg ttgaaaaaga tttggcctac aagacagttg agaaaaaaga ttcaacactg
     6481 tatctaggtg aaactcgtgt agaacaagaa ggaaaaactg gtaaagaacg tatctttaca
     6541 gcgattaatc ctgatggaag taaggaagaa aaactccgtg aagtggtaga agctccgaca
     6601 gaccgcatag tcttggttgg aaccaaacca gtagctcaag aagctaaaaa accacaagtg
     6661 tcagaaaaag cagatacaaa accaattgat tcaagtgaag ctagtcaaac taataaagcc
     6721 cagttaccaa atacaggtag tgcggcaagc caagcagcag tagcagcagg tttagctctt
     6781 ctaggtttga gtgcaggatt agtagttact aaaggtaaaa aagaagacta gaaattttga
     6841 taccttcttt atcattaaag accaaagaaa aactcttgtc ctaaatagaa gataaagagt
     6901 ctggaacaaa atagttctca accacaaaaa agctagatat ttccaattgc ggaactctag
     6961 ctttttaatt ttgagtcgtt ctcttattgt atagtagatt gaaactagaa tagtacactt
     7021 ctacttctaa aacattgtta gaaatcaatt tgactgtcct tatcgatttg tcctgttctt
     7081 atttcatttc actatgtttt aggaggttat tggccataag taccaatccc atgtcaattc
     7141 tcacttgacg cttccctctc agattacatc tcttgtaacc caaacaagcc tttatctgcc
     7201 caaagacagg ttccacatca atcttgcgtt gagcgaaaat ctgtctacct tggggagata
     7261 aaagcgcctg acattcttta gctttcaagt tttgatagcg ttcgttcata tacagtccct
     7321 tttgagggac tgattcaggt tcatcagcgt agtaaacctt gatttcctgt tgaaagtctg
     7381 tctgtgtttt ctggtacttg atatggtgaa aacgatagca ccagccatca ggatgtgtgt
     7441 agctatcctc cttgtcatta tagtgccaat tcgctaagtt tttagctgac tgtttatacc
     7501 ctctcttttg ttccttatca aacatggcat atttaatcag aaggggagtg atttcttctt
     7561 gaaaatagac ctgtatctgt tcttgaagtt tggcggagaa tttctctgtc gttttcttcc
     7621 acacaaaact atacttgttg gcattggctt caatcttagt tccgtcaata aacaaacaat
     7681 ctaaggtcac taactcttcc atttttcaat ttttcgacca gagaaaatcc cttgtgaata
     7741 ggcaaataga agagtagata caagcatttt agggtgataa gacgggcgat caaaggcatg
     7801 atagaaggcg tggaagtgac aatcctccaa ggtattcacc actttttcaa tagtaaaaac
     7861 gagatgatct tgtggcaaga aggaactgat ttctagtggt aaagttgttt gatttgtgtt
     7921 atagtgaata tgcatgggat agcctttcta aatggtttat taagcaattc tattttacca
     7981 agactatcgc aaccatgcaa aaaagcaacg gcaaatccgt tgcctttttt ggagataaga
     8041 gactattgtc ccagactctt ttctttgtat aaaattgtat agtgttattg tctatactat
     8101 tttgtagaga aagcaaaaat ccctagaaaa tgcttaggga ttcgactatt tcattaagaa
     8161 caattcaaca atcatttcta tatacatgat aagggttaat aagaatcctg cacgccagaa
     8221 gaatttgata aatttaggat agtaaaagct gcgttttttc aaaaggaaga aaaagacgag
     8281 aataatggct aggatcgaga gggctagccc cagtctaggg aggaaattat gggtaaaggt
     8341 tttagctgta atcaagtaat actcaaatac caagactgga aaagccaaat ccgcaaagtt
     8401 tcgtcctagt ttttttaatc taaaaagttt ggttaggata atgcagacga ctaaggtcag
     8461 tatcaataat aaaatagatg ctaatttcat taaaatcata cccatattgt atcataaaaa
     8521 aaggctaatg gaaacgagaa acagaggaat ttataggaaa gtcaggcttt tgagattgtg
     8581 ggtgattttt gttataatga aagttataaa atcttataat accttgaatg attattatcg
     8641 aaaactcttt ggagaaaaga cttttaaagt ccctattgat gcgggatttg actgtcccaa
     8701 tcgtgatgga actgtggctc atggaggctg tactttttgt acggtttccg gttctggaga
     8761 tgccattgtg gcaccagatg cgcctatccg tgagcaattt tataaggaaa ttgactttat
     8821 tcatcgtaag tggccagatg ttcagaagta tctggtttat tttcaaaatt ttaccaacac
     8881 ccatgaaaag gtggaagtta ttcgagagcg ttatgaacag gctatcaatg agccaggtgt
     8941 ggtaggaatc aatattggaa cgcgcccaga ctgtttacca gacgaaacca tcgaatattt
     9001 ggctgagtta tcggagtgca tgcatgtgac ggttgaattg ggcttgcaaa ctacttatga
     9061 agcaacctct gacctgatta accgtgcgca ttcttatgaa ttgtaggtgg aaacggtcaa
     9121 gcgtttgaga aagtatccaa aaattgagat tgtttcccat ttgatcaatg gtttgcctgg
     9181 tgaaacccat gagatgatgg ttgaaaatgt ccgccgttgt gtcacggata acgatattca
     9241 agggattaaa ctgcatttgc tccatcttat gacaaatact cgtatgcaac gagattacca
     9301 tgaggggcgt ttacaattga tgagtcagga cgaatatgtc agggtcatct gtgaccaact
     9361 ggaaattatt cccaaacata tcgtcatcca tcgaattaca ggagatgcgc ctagggatat
     9421 gctgcttggg cctatgtgga gcctcaataa atgggaagct ctcaacagca ttgagatgga
     9481 gatgcgacgt cgtggaagtg ttcaaggatg caaggctgta aaacaggagt ttgaaaatga
     9541 aaagaccact tgagatggca catgattttt tggctgaggt cgtgacaaaa gaggatgtcg
     9601 tagtggatgc gactatggga aatggtcatg acacgctttt tttagccaag ctagccaagc
     9661 aagtctatgc ctttgatatt cagaagcaag ccttggaaaa gacccaagag cgtttgcatc
     9721 aggctgactt gacaaatgcc cagttaatct tgcaaggcca tgagacactg gaccagtttg
     9781 tgataaaagc taaggcaggg atttttaatc tgggctattt gccgtcagct gataagtctg
     9841 tcatcacccg accgcagaca acgattgagg cattagaaaa gctatgtggc ttacttgtca
     9901 aaggtggacg aattgctatt atgatttact atggtcatga aggaggcgat ctcgagagag
     9961 atgctgtctt ggattttgtg atccagttga accaacaaga gtacacagct gccatttacc
    10021 gaactttaaa ccaagtcaac aacccgccgt ttttagtgat gattgaaaaa ttagagagat
    10081 acagacatgg ataaacaata cctacacgaa aagctggatg ccatgcgcca gaattttgtt
    10141 gaatcaaccc accacgaacg atcggtgggc gtgctagacc aagcgcatat gagcaaaaaa
    10201 atgcttaaaa tcaagaaaaa attagttgct cttgaaatgg aacggtgcca gagaaaaatt
    10261 gagcacaaag actgttccaa gattgaccaa aaaatcaaag agcagaagga gatatttgaa
    10321 tcctgttgta aaaaagatta aggaggacgt gcgtggaatt actgatttac ctcatcctat
    10381 ttttactggt tttgattgtc tcaagtacaa ccaataagct cctgcccttt ttgcctctcc
    10441 ctttggtgca gattcttttg ggaattgtga ttggtctctt tttacccaat actgactttc
    10501 accttaatac ggagttgttt ttggcactgg ttatcggacc cttgcttttc cgagaggctg
    10561 aagaagcaga tgttacggct attttaaaac actggcgaat cattgtttat ctcatatttc
    10621 cagtgatttt tatctcgacc ttgagtttgg gtggcttggc ccatcttctt tggttcagcc
    10681 ttcccttggc agcttgcttg gctgttgggg cagcccttgg tcctacggac ttggtggcct
    10741 ttgcctctct ttcggagcgt tttagctttc ctaagcgcgt gtccaatatt cttaagggcg
    10801 aaggactctt gaatgatgct tctggtttgg tggcttttca ggtagctttg acagcttgga
    10861 caactggagc tttttctctg gggcaagcta gcagttcgct catcttttca atcctaggcg
    10921 gttttttaat tggattttta acggccatga ccaaccgctt cctccatacc ttcttgctaa
    10981 gtgtgcgcgc aacggatatt gccagtgaac ttttattaga attgagtttg cctctagtga
    11041 ccttctttct ggcagaagaa gttcatgttt caggtattat tgccgtcgta gttgctggaa
    11101 ttttaaaggc aagtcgcttc aagaaaatca cgctcctcga agcccaagtg gatacggtga
    11161 ccgagacggt ctggcataca gtgaccttta tgctcaacgg ttctgtcttt gtgattttag
    11221 ggatggagtt ggaaatgata gcagaaccta tcttgaccaa tccaatctat aatcctctac
    11281 ttttattgct atctctcatc gcccttacct ttgtcctctt tgtcattcgt tttattatga
    11341 tctatggcta ttatgcctat agaacccgac gcctcaagaa aaagctaaat aagtatatga
    11401 aggacatgtt tctcttgacc ttttcaggtg ttaagggaac ggtgtcgatt gctacgattc
    11461 tcttgatacc aagtaatcta gaacaggagt atcctctttt gcttttcctt gttgcaggtg
    11521 tgacgcttgt cagcttttta acaggtctct tggtcttgcc tcatctttct gatgaagagg
    11581 aagaaagcaa ggattatctc atgcatatcg ccattttgaa tgaagtaacg ctagagttgg
    11641 aaaaagagtt ggaagacacc agaaataaac ttcccctcta tgcggctatt gacaattatc
    11701 atggacgtat tgaaaatctc attttaagcc aagaaaacca ggatgatcaa gaagattggg
    11761 ctgctttgaa actcttgatt cttagtattg aaagtgatgg tttggaacag gcctatgaag
    11821 aggggaacat tagcaatcgt gcttaccgag tttaccaacg ttatctgaaa aatatagaac
    11881 aaggaatcaa tcgtaaactt gcctcaagac tgacctatta ttttcttgtt tccttgagga
    11941 ttttacgttt tctccttcat gaagttttta ctcttggaaa gaccttccgt agctggaagg
    12001 acaaggagca aagccgtctc cgtgctcttg attatgacca aattgcagag ctctatcttg
    12061 ccaatacaga gatgattatt gaaagtttgg aaaacctgaa gggagtctac agacgctctt
    12121 tgattagttt tatgcaggag tctcgtcttc gagaaacagc tattatcagc agtggtgcct
    12181 ttgtcgaacg ggttatcaat cgtgtcaaac ccaacaatat cgatgaaatg ctgagaggct
    12241 attatctgga gcgcaagttg attttcgaat acgaagaaaa acgattgatt acgactaagt
    12301 atgccaagaa attacgacaa aatgtaaata acttagagaa ctattccttg aaggaagctg
    12361 ccaataccct gccgtatgat atggtggaat tggtaagaag aaattagtta atactcttcg
    12421 aaaatctctt caaaccacgt cagcgtcgcc ttggattata tatgtgactg acttcgtcag
    12481 tttcatctac aacctcaaag cagggctttg agcaacctgc ggctagcttc ctagtttgct
    12541 ctttgatttt cattgagtat aagattataa atgaaggagt atgacatgaa aaagtggtgg
    12601 aaagagctga tagacaagcc tttattaaaa gcttttttgc attattatca agcatcagat
    12661 agtgagttga ccagtgtcgc agtagcctac tattggttga tttcgatttt ccccctgctt
    12721 ttggtggtgg tcaatatcct cccctatttt cagattcctg tgggagaatt tctgtgcttt
    12781 atgaaagacg ttctgccccc aagcctctat gaaggtgtgg aaaaaatagc cagagaagtt
    12841 ttgacgcaac cttcaacagg tttattgagt ttttctgttt tatcggcgtt atggagtttt
    12901 tcaaaatcta tgaatttctt gcaaaaagct tttaacaagg cttatggcgt cgaaaagagt
    12961 cgtggactta tttcccatca gatgctaagt ctcctagtca gttttggctt gcagctcctc
    13021 tttgcgtttg ccttgttttt gatcttattt ggtcagatga ttttggcttt acttgctcat
    13081 tattggacaa aagatggcat tatctatcag gctttacaag ggttggcagg tcctctgatt
    13141 tacgccctcc tctttgctat cttggtcatg ctttattatt ttcttcccaa tctatctaac
    13201 aggaaaatta gctataccct accaggcagt gcctttgttc tcttagtgat tttaggttta
    13261 ctaactctgt tctctagtta tctcaattac tatgtccatc atttggtgga tgtccgaatt
    13321 ttaggttccg ttcttcttgt tgttatgatg ttttggttta tcttgattgc taaaattgtt
    13381 atcctaggcg cggttatcaa tgccagtatg cagagtttga aagatccggt ctttaaaaaa
    13441 gactaactat ttatccatta caaaagcgca tagtatcaaa actttataga accttgatac
    13501 tatgcgcttt tgtgctttga cagttttttg tatagttttt gtccaagatt tctaaatcat
    13561 ctgattaaat tcctattttc ccctatcatt gtccctgttt tttcgaaaat ggaaggagta
    13621 taataaatct atcaataaaa tgataggagg aactttatgg gtcatatttt cttttttcta
    13681 agtgtctttt tggcagggat tctatccttc ttttctcctt gtatcttacc tttgttaccg
    13741 gtctatacag gagtgttact agatgataag gatggtgctc aggcttctag cggcaaattt
    13801 tcaatctcag ttactagttt attacgaact ctggccttta tagcaggaat ttcctttata
    13861 tttattttgt tgggctatgg agctggtttt ttaggcgatt tgctttatgc ttcttggttc
    13921 caatatctta ctggggcaat tattatcctt cttggtttgc accaaatgga gattctacac
    13981 tttaaggggc tttataagga aaagaggcta caactgcaag gacaggggca aaatggtaag
    14041 ggctatagtc aggcattttt attgggcttg acctttagtt ttgcttggac gccttgcgtg
    14101 gggccggttc tggggtctgt tttggccttg gcggcttcag gtggttcagg agcttggcag
    14161 ggagctggtc tcatgttggt gtatacgctg ggcttggcgc taccattctt gcttctagct
    14221 ctgacctcta gttatgtttt gaaacatttc cgaaaacttc atccctatct cggaatcctc
    14281 aaaaaagtgg gtggttttct cattattgtg atgggactct tggttctgtt tggaaatgct
    14341 tcaattttaa gtcaattatt tgaataaaat ggaaaggaat atcaatatga aaaaatggca
    14401 aacatgtgtt cttggagcag gttcgctcct ttgtttgacg gcttgttcag gcaagtccgt
    14461 gactagtgaa caccaaacga aagatgaaat gaagacggag cagacagcta gtaaaacaag
    14521 cgcagctaaa gggaaagagg tggctgattt tgaattgatg ggagtagatg gcaagaccta
    14581 ccgtttatct gattacaagg gcaagaaagt ctatctcaaa ttctgggctt cttggtgttc
    14641 catctgtctg gctagtcttc cagatacgga tgagattgct aaagaagctg gtgatgacta
    14701 tgtggtcttg acagtagtgt caccaggaca taagggagag caatctgaag cggactttaa
    14761 gaattggtat aagggattgg attataaaaa tctcccagtc ctagttgacc catcaggcaa
    14821 acttttggaa acttatggtg tccgttctta cccaacccaa gcctttatag acaaagaagg
    14881 caagctggtc aaaacacatc caggattcat ggaaaaagat gcaattttgc aaactttgaa
    14941 ggaattagcc taggaggtgt cttatgaatg ataagttaaa aatcttcttg ttgctaggag
    15001 tattttttct agccataacc ggtttctatg ttctattgat acgaaatgca gggcagacag
    15061 atgcctcgca aattgaaaag gcggcagtta gccaaggagg aaaagcagtg aaaaaaacag
    15121 aaattagtaa agacgcagac ttgcacgaaa tttatctagc tggaggttgt ttctggggag
    15181 tggaggaata tttctcacgc gttcccgggg tgacggatgc cgtttcaggc tatgcaaatg
    15241 gtagaggaga aacaaccaag tacgaattga ttaaccaaac aggtcatgca gaaaccgtcc
    15301 atgtcaccta tgatgccaag caaatttctc tcaaggaaat cctgcttcac tatttccgca
    15361 ttatcaatcc aaccagcaaa aataaacaag gaaatgatgt ggggacccag taccgtactg
    15421 gtgtttatta cacagatgac aaggatttgg aagtgattaa ccaagtcttt gatgaggtgg
    15481 ctaagaaata cgatcaacct ctagcagttg aaaaggaaaa cttgaagaat tttgtggtgg
    15541 ctgaggatta ccatcaagac tatctcaaga aaaatccaaa tggctactgc catatcaatg
    15601 ttaatcaggc ggcctatcct gtcattgatg ccagcaaata tccaaaacca agtgatgagg
    15661 aattgaaaaa gaccctgtca cctgaggagt atgcagttac ccaggaaaat caaacagaac
    15721 gagctttctc aaaccgttac tgggataaat ttgaatccgg tatctatgtg gatatagcaa
    15781 ctggggaacc tctcttttca tcaaaagaca aatttgagtc tggttgtggc tggcctagtt
    15841 ttacccaacc catcagtcca gatgttgtca cctacaagga agataagtcc tacaatatga
    15901 cgcgtatgga agtgcggagc cgagtaggag attctcacct tgggcatgtc tttacggatg
    15961 gtccacagga caagggcggc ttacgttact gtatcaatag cctctctatc cgctttattc
    16021 ccaaagacca aatggaagaa aaaggctacg cttatttact agattatgtt gattaatact
    16081 cttcgaaaat ctcttcaaac cacgtcagcg tcgccttacc gtatgtaggg tt
//
LOCUS       DAVBIC010000051        14798 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.051, whole genome shotgun sequence.
ACCESSION   DAVBIC010000051 DAVBIC010000000
VERSION     DAVBIC010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14798)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14798)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14798
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.051"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            <1..662
                     /locus_tag="VQ664_001704"
     CDS             <1..662
                     /locus_tag="VQ664_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789826.1"
                     /translation="IIRKVQEPEFWKEVNLSDLEKIRLAIRDLLQFLDKTDRKPYYVN
                     FEDRILSTVHETTAFLQVNDLRSYNEKVEHYLKTHLDEESISKLYHNKKLTSDDMLAL
                     EKLLWEKLGSKADYQSHYENKAIPRLVREIIGLDRESANRIFSKFLSDENLNARQISF
                     VKLIVDYIVENGFLETKVLTQEPFKSYGSVQLLFQHQLPVLRNIVQIIELINNRAGEA
                     A"
     gene            complement(1062..2408)
                     /locus_tag="VQ664_001705"
                     /pseudo
     CDS             complement(1062..2408)
                     /locus_tag="VQ664_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element ISSpn5 family transposase"
     gene            2470..2664
                     /locus_tag="VQ664_001706"
     CDS             2470..2664
                     /locus_tag="VQ664_001706"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789827.1"
                     /translation="MSSKKHPLGEKRNHTGSKLRQGFWMVFRLGVNNWGFKEIENKKP
                     SKNSIAGENEIILNENQRAN"
     gene            2642..2842
                     /locus_tag="VQ664_001707"
     CDS             2642..2842
                     /locus_tag="VQ664_001707"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789828.1"
                     /translation="MKIKEQTRKLAAGCSKHCFEVVDKTDEVSSKHGFEVVDETDEVS
                     NHTYGKATLTRIEEIFEEYKSS"
     gene            complement(2922..3367)
                     /locus_tag="VQ664_001708"
                     /pseudo
     CDS             complement(2922..3367)
                     /locus_tag="VQ664_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000547411.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            3375..3518
                     /locus_tag="VQ664_001709"
     CDS             3375..3518
                     /locus_tag="VQ664_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789829.1"
                     /translation="MAERFWENLSIILADRNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRH"
     gene            3611..4198
                     /locus_tag="VQ664_001710"
     CDS             3611..4198
                     /locus_tag="VQ664_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2789830.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCSDELTILQILYGASLIS
                     FLWMYGQRKQVIKVNMKTRIQWLGIGFVSLLIISLCFSLIHAQESTNQANLIGLQHQI
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALAHHPGTIIAWCLYV
                     SLGMFLGLVRYKLDLWGSMGLHLVWNLLVYSLLLF"
     gene            4596..5405
                     /locus_tag="VQ664_001711"
     CDS             4596..5405
                     /locus_tag="VQ664_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000926538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HET2789831.1"
                     /translation="MLLQKELIPMIEANLPNMAYAEKDIAKFFLKQQPLNNYSCKALC
                     ECLNVSKATLTRFAKKCGFKGFRQFIFKYQEMIREKEKLALYTEATEKVLSDYEEMLR
                     KTYTVLDEVQLERIAEMIETAERVYLYGKVSSVLALQEMKMRFMRLGVIGEVLSDEDM
                     ILWNSLLLNENCLVIGASVSGQTDIVLEGLQKAADKGAKTVLMTTRKFDEEDCFFDEL
                     LLLASTNHLSYGNRISPQFPILLITDCLFSHYLESPERQYYYNQTIIHKEE"
     gene            5410..6111
                     /locus_tag="VQ664_001712"
     CDS             5410..6111
                     /locus_tag="VQ664_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HET2789832.1"
                     /translation="MSQIWTKEKFISQVHGGVIVSCQALPGEPLYNEEFSLMPFMAKA
                     ALEAGAVGIRANSVRDIKAIQKVVDLPIIGIIKRDYPPQEPYITATMKEVDELVECGT
                     TVIAFDATLRPRYDGLVINEFIKKIKEKYPNQLLMADVSNFDEGLYAFKSGVDFVGTT
                     LSGYTSTSVQSDEPDFELMKKLADFNIPVIAEGKIHYPEQLKKAYSLGVTSVVIGGAI
                     TRPKEIAQRFINVIK"
     gene            6136..7053
                     /locus_tag="VQ664_001713"
     CDS             6136..7053
                     /locus_tag="VQ664_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate lyase"
                     /protein_id="HET2789833.1"
                     /translation="MKDLTKYKGVIPAFYACYDENGEISQERVKSLVQYFIDKGVKGI
                     YVNGSSGECIYQSVEDRKQIIEAVMEVAKGKLTVINHVACNNTKDSIELAKHSESVGV
                     DAIAAIPPIYFKLPEYSIAAYWNAMSEAAPNTDFIIYNIPQLAGVALTGSLYATMRQN
                     PRVIGVKNSSMPVQDIQMFVAAGGEDYIVFNGPDEQYLGGRLMGAEAGIGGTYGVMPD
                     LFLKLESLIQERDLDTAKKLQYAINEVIYKMISGKANMYAVAKEVLRLNEKLDLGSVR
                     QPLEALAEGDLEVAKQAAELIQQARKEFL"
     gene            7081..8622
                     /locus_tag="VQ664_001714"
     CDS             7081..8622
                     /locus_tag="VQ664_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HET2789834.1"
                     /translation="MGTTGFTIIDLIILIVYLLAVLVAGIYFSKKEMKGKEFFKGDGS
                     VPWYVTSVSIFATMLSPISFLGLAGNSYAGSWILWFAQLGMVVAIPLTIRFILPIFAR
                     IDIDTAYDYLDKRFNSKALRIISALLFIIYQLGRMSIIMYLPSAGLSVLTGIDINILI
                     ILMGAVAIVYSYTGGLKSVLWTDFIQGVILISGVVLALFVLMANIKGGFGAVAETLAN
                     GKFLAANEKLFDPNLLSNSIFLIVMGSGFTILSSYASSQDLVQRFTTTQNIKKLNKML
                     FTNGVLSLATATVFYLIGTGLYVFYQVQNAGSAASNIPQDQIFMYFIAYQLPVGITGL
                     ILAAIYAASQSTISTGLNSVATSWTLDIQDVISKNMSDDRRTKIAQFVSLAVGLFSIG
                     VSIVMAHSDIKSAYEWFNSFMGLVLGLLGGVFILGFVSKKANKQGAYAALIVSTIVMV
                     FIKYFLPPTAVSYWAYSLISISVSVVSGYIVSVLTGNKVSAPKYTTIHDIPEIKADSS
                     WEVRH"
     gene            8641..9099
                     /locus_tag="VQ664_001715"
     CDS             8641..9099
                     /locus_tag="VQ664_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HET2789835.1"
                     /translation="MIISEQSDFRRYASINKHFSKVCDFLENTNLTDLVDGKVDIDGE
                     NVFANCMIYLADGVPGDIFETHKKYLDIHIVVENTEKMAVTSPVRAQSRVPFSEEKDI
                     AFYDSKDYQIVELLPGNMLVTFEEDLHQPKIHCNDEPVKKLVIKVLNEEK"
     gene            9101..11323
                     /locus_tag="VQ664_001716"
     CDS             9101..11323
                     /locus_tag="VQ664_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exo-alpha-sialidase"
                     /protein_id="HET2789836.1"
                     /translation="MKKNIKQYVTLGTAVVLSAFVANSVAAQETETSEVSTPELVQPV
                     APTTPISEVQPKSGNSSEVTVQPRTVETTVKDPSSATEETPVLEKNNVTLTGGGENVT
                     NELKDKFTSGDFTVVIKYNQSSEKGLQALFGISNSKPGQQNSYVDVFLRDNGELGMEA
                     RDTSSNKNHLVSRPASVWGKYKQEAVTNTVAVVADSVKKTYSLYANGTKVVEKKVDNF
                     LNIKDIKGIDYYMLGGVKRAGKTAFGFNGTLENIKFFNSALDEETVKKMTTNAVTGHL
                     IYTANDTTGSNYFRIPVLYTFSNGRVFSSIDARYGGTHDFLNKINIATSYSDDNGKTW
                     TKPKLTLAFDDFAPVPLEWPRDVGGRDLQISGGATYIDSVIVEKNNKQVLMFADVMPA
                     GVSFREATRKDSGYKQIDGNYYLKLKKQGDTDYNYTIRENGTVYDDRTNRPTEFSVDK
                     NFGIKQNGNYLTVEQYSVSFKNNKKTEYRNGTHVHMNIFYKDALFKVVPTNYIAYISS
                     NDHGESWSAPTLLPPIMGLNRNAPYLGPGRGIIESSTGRILIPSYTGKESAFIYSDDN
                     GASWKVKVVPLPSSWSAEAQFVELSPGVIQAYMRTNNGKIAYLTSTDAGTTWSAPEYL
                     KFVSNPSYGTQLSIINYSQLIDGKKAVILSTPNSTNGRKHGQIWIGLINDDNTIDWRY
                     HHDVDYSNYGYSYSTLTELPNHEIGLMFEKFDSWSRNELHMKNVVPYITFKIEDLKKN
                     "
     gene            11363..12472
                     /locus_tag="VQ664_001717"
     CDS             11363..12472
                     /locus_tag="VQ664_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HET2789837.1"
                     /translation="MVNYGIVGAGYFGADLARSMNKIEDAKVVAVFDPNHGEEVAQEL
                     GSDVCASLDELVAREDIDCVIVASPSYLHREPVVKAAQHGKHVFCEKPIALSYEDCKA
                     MVDACKENNVIFMAGHIMNFFNGVHHAKELITQGKIGKVLYCHAARTGWEEQQPTVSW
                     KKLRSQSGGHLYHHIHELDCIQFIMGGLPEKATMVGGNVYHKGENFGDEDDMLIVNLE
                     YSDDRYAVLEYGNAFRWGEHYVLIQGTEGAIKLDLFNTGGTLRVKGEGESHFLVHETQ
                     EEDDDRTAIYTGRGMDGAIAYGKPGVRCPLWLQTCIDKEMEYLHDIIKGGEITEEYEK
                     LLNGVAALESIATADACTLSVKEDRKVSLSEITNA"
     gene            12629..13519
                     /locus_tag="VQ664_001718"
     CDS             12629..13519
                     /locus_tag="VQ664_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET2789838.1"
                     /translation="MKIIGIDIGGTTIKADLYNEFGTSLNQFKEIETIIDYDLGTNQI
                     LNQVCDLIGEYILNHSIDGVGISTAGVVNANTGEIIYTGYTIPGYIGVNFTFEIEKRF
                     GLSTFVENDVNCAALGELWKGQAKDKKNVVMVTIGTGIGGSIIVNGQIVNGFNYTAGE
                     VGYIPVGNSDWQSKASTTALIHLYQKKSLKTNQTGRTFFTDLRAGDKVAKETFEIFVE
                     NLTKGLLTITYLLNPEILILGGGILAKKDILLPEIQSSLAKNAMDNRFLPKNLVAATL
                     GNEAGRIGAVKNFLDRISNK"
     gene            13544..13867
                     /locus_tag="VQ664_001719"
     CDS             13544..13867
                     /locus_tag="VQ664_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789839.1"
                     /translation="MTNSVFSTMQDIENVATDIIKSYDNEIYTYKAVSQEELEKLEKS
                     YDEKSHEELVSIESNLEMKQQNLIDEVNKTIKENYEKIQYISSSRRGEFVEKIIGRVV
                     EKYGY"
     gene            13857..14798
                     /locus_tag="VQ664_001720"
                     /pseudo
     CDS             13857..14798
                     /locus_tag="VQ664_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018351.1"
                     /note="Produces ATP from ADP in the presence of a proton
                     gradient across the membrane. Subunit I is part of the
                     membrane proton channel.; internal stop; incomplete;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
BASE COUNT         4959 a         2254 c         2929 g         4656 t
ORIGIN      
        1 aaattatcag gaaagtacag gagcctgaat tttggaaaga agttaacttg tctgatttgg
       61 aaaaaattcg tcttgctatt cgagatttat tacagttttt ggataaaaca gaccgtaaac
      121 cctactatgt taactttgaa gatcgtatac tctccactgt tcacgagacc acagcatttt
      181 tgcaggtcaa cgatcttcgg tcttacaatg aaaaagttga gcattatttg aaaactcatc
      241 tggatgagga gtccatttct aagctatacc ataataaaaa gttgacatct gatgatatgc
      301 ttgcacttga aaaattgctt tgggaaaaat taggtagtaa agcagactac caaagtcatt
      361 atgaaaataa ggcaattccg agattggttc gtgagattat tggcttagat agagagtctg
      421 ccaatcgtat tttctctaaa tttttgtcgg atgagaatct taatgccagg cagatttcat
      481 ttgtaaaatt gattgtagac tacattgtag aaaatggttt tttagagacg aaagtgttaa
      541 cgcaagagcc gtttaaatct tatggttctg ttcaactact cttccaacac caactaccag
      601 tacttcgtaa tattgttcaa atcattgaac ttatcaataa tcgagctgga gaagcggctt
      661 aaattctaaa gtgattgcca tgctgagact catttaaaat taaaaagagt agaaatttat
      721 gctatatatg agaagtttta ttaggaagaa tgtcatcgtt ttcctagaat acagtatcag
      781 ttgttaagtg gttgataaat ttcaaagtag atacttgtac cacgatgttt gttgatcgag
      841 ttattaacaa aagagctact ttgattttaa cccaaatcat tcatacctct ctcaactaga
      901 tgtaacttac aaaacccctg acctcatgag ccactttctt cctcctcatg aggtcagttt
      961 tactttctgc tgttccagta tcgtttttcc tcgctagatt tcctcaaaag ggcagactcc
     1021 tcccttggtg cgtcacacga ttttttcatc tcgactgttc tttaatgcat cattaacgac
     1081 gcttttcttc caggtggttc ataaggaaca ggaagattca ggttgacttt tctaatccta
     1141 gaataaagtg ctgaaaacaa ttcggaatag gcatagagac tagacaattt gaggagctgc
     1201 ttgcgtcctg ttcgaacaca ttttcctacc acgtgaagaa aaagatggcg gaagcgtttg
     1261 attgttaaag tttggaagtc acctccagct agatgtttga gaaaaagata gagattgtag
     1321 gcgatacagc tcatcatcat acgaacttcg tttttgatta aggttgaact atccgtttta
     1381 tcgccaaaaa atccctcctt catctccttg atgaaattct cggcttgacc acgtccacga
     1441 taaagctgaa actggtcttg gcttgttcca ctcgtcatat ttgtaacgag agaaataaca
     1501 tcgtagaaca agtttccttc ttttcgttca gagaactggc agacacgacg cttgtgcgac
     1561 caagatcctg cttgatagag agtttctgag taggcggagt ggggcaagat ggttaagtcc
     1621 tcatcctgtg ggcaagggag ggaaaggtct ccaagacggc tcagaacagt atttttcttg
     1681 agttttatga gttagtattg ccctgttttt tcaattaaat cgtataattt gggggtcgca
     1741 aagccactat ccattcgaaa gagaagttga ttaaaccgtt ctaaaacagg tgtgataaag
     1801 ctgtctgcct cttcagaaca ataacgatta ccaggacgaa gctgggcatt gaaacaataa
     1861 cctgtcttcc cctcgaaagc ataaagagga tgatagccat gagcacgata gtgggcgtta
     1921 taagcaacac cttcttgctt gccataagtt gtgaaatggg tagaatcgat atctacaatg
     1981 agttggttta gctggtgaaa ctgtaaaaag aattcgacca attcaaggtt gaggcatcgc
     2041 aaactatgga ctgtttcctc gtcagttctg gaaagaaaac gggataaggt tggctgtgaa
     2101 gcaagctgcc ctccttccaa caattttgga aagtaggcat cagctgacaa ttctttacaa
     2161 gcatagtccg ttccatagcc tgttaacagt tgaaagagga actggacaag gatatctgaa
     2221 tccgaataac gacagtagcg gcgttggtca ttcgttacta aatacttaga aatccgctct
     2281 tttagtttca actgggaaaa aagttcctga aaaaagataa gaccaccata ctgggttaaa
     2341 tgacctccat cgaaagatag ttggtaaaaa gacttgtttt ggaagtgatg atttggtaaa
     2401 ctgttcatgt gagtttcctt tctttttgtg tttttttcta cacttatacc ataaagggga
     2461 aattcttttt tgtctagtaa aaaacaccca ttgggtgaaa aaagaaacca tacaggatct
     2521 aagctaaggc aaggattctg gatggttttt agattagggg tgaataattg gggttttaaa
     2581 gaaatagaaa acaaaaagcc gagcaagaat tcaattgcag gagaaaatga aataatactc
     2641 aatgaaaatc aaagagcaaa ctaggaaact agctgcaggc tgctcaaaac actgttttga
     2701 ggttgtagat aagactgacg aagtcagctc aaaacatggt tttgaggttg tagatgaaac
     2761 tgacgaagtc agtaaccata cctacggcaa ggcgacgttg acgcggattg aagagatttt
     2821 cgaagagtat aaatcttcct aggataaagc aaagagcctg ggacaaaata gttctcgacc
     2881 acaaaaaagc tagagatttc caattgtgga actttagctt tttaattttg agtcgttctc
     2941 ttattgtatt ttaggaggtt attggccata agtaccaatc ccatgtcaat tctcacttga
     3001 cgcttgcccc tcagattaca tctcttgtaa cccaaacaag cctttatctg cccaaagaca
     3061 ggtgacattc tttagctttc aagttttgat agccttcgtt catatacagt cccttttgag
     3121 gggctgattc aggttcgtcg gcgtagtaaa ccttgatttc ttgtttaaag tctgtctgtg
     3181 ttttctgatg tttggtatgg tgaaaacgat aataccagcc atcaggatgt gtatagctat
     3241 cctccttgtc attatagtac caattcgcta agtttctagc tgactgttta tagcctctct
     3301 tctgttcctt atcaaacatg gcatatttaa tcagatggtt tacctccttt tcatctaact
     3361 aaaggagaag caatatggct gaacgatttt gggagaactt gtccattatt ttggctgaca
     3421 gaaatatcag ctggattgag ttaaccagaa aaatgtttgc gggagagttt cactatccaa
     3481 gtgaattgaa tcgtttgtat caaaagattc gccactagaa gatggaacaa cgaatgcctc
     3541 aaagtccatg ggtagaaagg attgtgcagg tattagattt agattatgaa gatttatttc
     3601 ggaggtaatt atgaaaagaa taattccagt ttatatattc caacaagtaa atgtcctatt
     3661 ggtatctcta tacttattga aatttctttg tagcgatgag ttaactatac tacagattct
     3721 ctatggagcg tcactcattt cttttttatg gatgtatggt caacgaaaac aagtgatcaa
     3781 ggttaatatg aaaactagga tacaatggct tggtattgga ttcgttagcc tactgattat
     3841 aagtctatgt tttagtctaa tccatgcgca agaaagcacg aatcaagcaa acttaattgg
     3901 acttcaacat caaattcctt ggttttcatt tttattgttt ttaatcaatg cgagtatggt
     3961 tgaagaattt ctgtatagag aaattttatg gaacttggtt agaaaattag atattcgagt
     4021 tgctttgaca agtgttttat ttgccttagc acatcatcca ggaaccatta tagcttggtg
     4081 tttgtatgta tcgctgggga tgtttttagg gcttgtacgc tacaaattgg acttatgggg
     4141 cagtatgggg ctacatttgg tgtggaacct actagtttat agtttgctgc ttttttaaaa
     4201 taagtgatct gatttatctc ataaatcagt agtttttata ggattatttt taattcggaa
     4261 acaaaaatgt attaacagca taaaataaag aaactaggaa catttttttt attttttaga
     4321 aataaaatgt tgtatagaaa ttccgaaaga aataataaaa tcaaaataaa aattaataaa
     4381 ataggtatat ttgaacatat tgacgtcgac aaatgttctt gcaagacata aaatacaaat
     4441 aaaaagaata aaaaattttt atatttttat atttgttgtt ctgttataaa atgaaagaaa
     4501 ttagaaacta gtttctaaat catgaaaaat attgaaaaaa aaaaataagt gttaaaataa
     4561 agaatgtaaa cgtttacttc aataaaggag ctcatatgtt actgcaaaaa gaactaattc
     4621 caatgataga agctaactta ccaaatatgg catatgctga aaaagacatt gctaaattct
     4681 tcttaaaaca gcaacctctg aataattatt catgtaaggc attgtgcgaa tgccttaatg
     4741 tatccaaagc aacattgact cgatttgcga aaaaatgtgg ttttaaaggt tttagacaat
     4801 tcattttcaa ataccaagag atgattcgtg agaaagaaaa gttagcattg tatacagagg
     4861 ctacagaaaa agttttatcc gactatgaag aaatgttgag aaaaacttac acggttcttg
     4921 atgaagttca acttgagcgt attgctgaga tgatagaaac tgctgagcgt gtatatcttt
     4981 atggtaaagt aagttctgtt cttgctttac aagaaatgaa gatgagattt atgcgtctcg
     5041 gagtcattgg tgaagtatta tcagacgagg atatgatttt gtggaatagc ttattactta
     5101 atgaaaattg ccttgtcatt ggagcatccg tttcaggtca aactgatatt gtactagaag
     5161 gtcttcaaaa agctgcggat aaaggcgcta aaacagtttt aatgactaca agaaaatttg
     5221 acgaagaaga ttgtttcttt gatgaactat tgttattagc ttcgaccaat catctctcgt
     5281 atggcaatcg catatcacct cagtttccaa tacttttaat tacagactgc ttattctctc
     5341 attatctgga aagtccagag agacaatatt attacaatca aactattatc cataaggagg
     5401 aataataaaa tgagtcaaat ttggactaaa gaaaaattta taagtcaagt ccatggtgga
     5461 gtcattgttt cttgtcaagc tttacccggt gaaccccttt ataatgaaga atttagcttg
     5521 atgcctttta tggctaaagc agctttagag gcaggagcag tgggcattcg cgcaaattct
     5581 gtgcgtgata ttaaagcaat tcagaaagta gtagatttac caataattgg aattatcaaa
     5641 agagattatc cacctcaaga accatatatt actgctacga tgaaagaagt agatgaactt
     5701 gtagaatgcg gaacaacagt cattgcattt gatgcaactt taagaccaag atatgatggc
     5761 ttagttatca atgaatttat caaaaaaata aaagaaaaat atcctaatca attgttgatg
     5821 gcggatgtaa gtaattttga tgaaggtctc tatgcattta aatcaggcgt tgattttgtt
     5881 ggtacaacat tatcagggta cacaagtaca agtgtacaat cagatgagcc tgattttgaa
     5941 ctaatgaaaa aattggctga ttttaatatt ccggtaattg ccgaaggaaa aattcattat
     6001 ccagaacaat taaaaaaagc ttatagttta ggtgttacca gtgttgtcat tggtggagcg
     6061 attacacgtc caaaagaaat tgctcagcga tttattaatg tcatcaaata aaaaacaata
     6121 taaaggagaa atctgatgaa agatttaact aaatacaaag gcgttattcc tgcattttat
     6181 gcttgctatg atgaaaatgg tgaaattagc caagaacgtg taaaatctct ggtgcaatat
     6241 ttcattgaca aaggtgtaaa aggtatctat gtaaatggtt cttcaggtga atgtatttac
     6301 caaagtgtag aagatcgtaa acaaattatt gaagctgtta tggaagttgc taaaggtaaa
     6361 ttaacagtta tcaaccatgt tgcatgtaat aacacgaaag atagtattga attggcaaaa
     6421 cattcagaaa gtgttggagt cgatgctatt gctgctatcc cacctattta cttcaaattg
     6481 ccagaatatt caattgcagc atattggaat gcaatgagtg aagctgcgcc aaatacagat
     6541 tttatcattt ataatattcc acaattggca ggggttgcgt tgactggtag tttgtatgca
     6601 acaatgcgtc aaaatcctcg tgtgattgga gttaaaaatt cttctatgcc tgtacaagat
     6661 attcaaatgt ttgtagctgc aggtggagaa gattacattg tattcaatgg tccagatgaa
     6721 caatatcttg gtggtcgctt gatgggagca gaagctggta ttggtggtac ttatggcgtt
     6781 atgccagatt tgttcttgaa attggaaagt ttgattcaag aacgagattt agatactgct
     6841 aaaaaacttc aatatgctat caatgaagtt atctataaga tgatatcagg taaggcaaat
     6901 atgtatgctg tagcaaaaga ggttttgcgt ctaaatgaaa aacttgattt aggttctgtt
     6961 cgtcaaccct tagaagcatt ggcagaaggt gacttggaag ttgcaaaaca agcagcagaa
     7021 cttattcaac aagcacgaaa agaattttta taataaataa aatcaatatg gagatatgtt
     7081 atgggcacaa caggatttac aataattgac ttaattatct tgattgttta tttacttgcg
     7141 gtgttggttg caggtatcta tttctctaaa aaagagatga aaggaaaaga gttcttcaaa
     7201 ggagatggtt cggttccttg gtatgttact tcggtatcca tttttgccac aatgctcagt
     7261 ccgatttcct tcttgggact cgctggtaac tcttatgcag gtagctggat tttatggttt
     7321 gctcaattag ggatggtagt agctattcca ctgacaattc gttttatctt acctatcttt
     7381 gcacggatag acatcgatac ggcatatgat tacttggata aacgttttaa ttctaaagca
     7441 cttcgtatta tttcagcact cttgtttatt atttatcaat tgggacgtat gtctatcatt
     7501 atgtacctcc catcagctgg tttatcagta ttgacaggaa ttgacatcaa tattttgatt
     7561 attttgatgg gtgcagttgc aattgtttat tcttacactg gtggtctaaa atccgtatta
     7621 tggacagact ttattcaagg tgtgattctg attagtggtg tcgttttagc tttatttgta
     7681 ctgatggcta atattaaagg tggctttggt gcagtagcag aaacattagc aaacgggaaa
     7741 ttccttgctg caaatgaaaa acttttcgat cctaacttgc tttcaaactc catcttttta
     7801 attgtgatgg gttcaggctt tacaatcttg tcttcctatg cttcatctca agatttggtt
     7861 caacgtttta ctacaacaca aaatattaag aaacttaata agatgttgtt cacaaacggt
     7921 gtcttgtcac ttgcaactgc aacagtcttt tacttgattg gtacaggctt gtacgtattc
     7981 tatcaagtac aaaatgcagg tagtgcagct agcaatatcc ctcaagacca aatctttatg
     8041 tactttattg cataccagtt accagtaggt atcacaggtt tgattttggc agcgatttat
     8101 gcagcatctc aatcaactat ttcaacaggt ttgaactctg ttgcaacttc atggacattg
     8161 gatattcaag atgtcatttc taaaaatatg tcagacgatc gtcgtacgaa aattgcacaa
     8221 ttcgtatctc tagcagtagg tttattctca attggtgttt ccattgtcat ggctcactca
     8281 gatattaaat ctgcatacga atggttcaat agcttcatgg gacttgtact tggtctactt
     8341 ggtggtgtat ttattcttgg atttgtttct aaaaaagcaa ataaacaagg tgcttatgca
     8401 gcgctgattg tatcaactat cgtcatggta tttattaaat acttccttcc tccaacagct
     8461 gtgagctact gggcatattc attgatttca atctctgtat cagtagtttc aggttatatt
     8521 gtatctgttc ttactggaaa taaagtatct gcacctaaat atacaacgat tcatgatatt
     8581 ccagaaatta aagcggattc aagttgggaa gttcgtcact aatagaaaag agaaaataat
     8641 atgattattt ctgaacaatc tgattttaga cgatatgctt ctatcaataa acatttttca
     8701 aaagtctgtg attttttaga aaatacaaat ttgacagatt tagttgatgg aaaagttgat
     8761 attgacgggg aaaatgtttt tgcaaattgt atgatctatc tagctgatgg agtcccagga
     8821 gatatttttg aaactcataa gaaatattta gatattcata ttgttgttga aaatactgaa
     8881 aaaatggcag taacttcccc agttcgtgcc cagtcacgtg taccttttag cgaagaaaag
     8941 gatattgctt tttacgatag caaagactat caaattgttg aattgcttcc agggaatatg
     9001 ttggtgactt ttgaagaaga tcttcaccaa ccaaagattc attgcaatga tgagcctgtt
     9061 aaaaaacttg ttattaaagt tttaaacgag gaaaaataaa atgaaaaaaa atattaaaca
     9121 atacgtaacc ttaggtactg cagtggtatt atcagcattt gttgctaact cagttgcagc
     9181 tcaggagact gaaacttctg aagtatcaac accagagttg gtgcaacctg ttgcaccaac
     9241 gactccgatt tcggaagtac aacctaaatc gggtaactct tcggaagtta ctgtacaacc
     9301 tagaacagtc gaaactactg ttaaggatcc atcttctgca acggaagaaa ctcctgtctt
     9361 agaaaaaaat aatgttactt taacaggggg cggagaaaat gttactaatg agttaaagga
     9421 taaatttact agcggtgact ttactgtagt gattaagtac aatcagtcta gtgagaaagg
     9481 cttacaagct ctgtttggaa tatctaattc taaacccggt caacaaaata gttatgtaga
     9541 tgtgttcctt agagacaatg gtgaattggg aatggaagcg cgtgatactt cttccaataa
     9601 aaatcaccta gtatccagac ctgcttcagt ttggggtaag tacaaacaag aagctgtgac
     9661 taacactgtt gcagtagtag cagattcagt caaaaaaaca tattctttat atgcaaatgg
     9721 tacaaaagta gtagaaaaga aagtggataa cttcttaaac atcaaggata ttaaaggtat
     9781 tgattactat atgcttgggg gagtgaaacg tgcaggaaaa acggcgtttg gttttaacgg
     9841 aacactagaa aatatcaaat tctttaatag tgcattggat gaagaaactg ttaaaaagat
     9901 gacaacaaac gctgttactg gacatttaat ttatacggct aatgatacaa caggttctaa
     9961 ctatttccgt attccagttc tgtatacttt tagcaatggt cgggtatttt caagcattga
    10021 cgctcgttac ggcggaactc atgatttttt gaataaaatt aatattgcta caagttatag
    10081 tgatgataat ggtaagacat ggactaaacc aaaattaaca ttggcattcg atgattttgc
    10141 gccagtacca ttagaatggc ctcgtgatgt tggtggacgt gacttacaaa tcagcggtgg
    10201 tgcaacctat attgactctg ttattgttga aaaaaataac aaacaagtac tcatgtttgc
    10261 ggatgtgatg cctgctggag taagttttag agaagctact agaaaagatt caggttataa
    10321 acaaattgat ggtaattatt accttaaatt aaagaaacaa ggtgatactg attacaatta
    10381 tactattcgt gagaatggta ctgtatacga cgatcgtacc aacagaccaa ctgaattttc
    10441 agtagataaa aatttcggta ttaaacaaaa tggtaattat ttgacagtag agcaatattc
    10501 ggtttcattt aaaaataata aaaagactga atatcgtaat gggactcacg tccatatgaa
    10561 tatcttctac aaagatgcat tgttcaaagt agtgccaacg aactatattg catatatttc
    10621 tagcaatgat catggcgaat cttggtctgc accaacttta ttacctccta taatgggact
    10681 taatcggaat gcgccttatt tgggtcctgg acgtggaatc attgaaagct caactggacg
    10741 tattcttatt ccgtcttaca ctggtaaaga gtctgcattc atttatagtg acgataatgg
    10801 agcatcttgg aaagttaaag ttgtgccact tccttctagt tggtcagcag aagcacaatt
    10861 tgtagaattg agtccaggag taattcaagc atacatgcgt acaaataatg gtaaaattgc
    10921 atatttaaca agtacagacg caggtactac ttggagtgca ccggaatatt tgaaatttgt
    10981 ttcaaatcca agttatggaa cacaattatc aatcatcaat tatagtcaac tgattgatgg
    11041 taaaaaggct gtcattttaa gtactccaaa ctccacaaat ggtcgtaaac acggacaaat
    11101 ttggattggt ctaattaatg atgataatac aattgattgg cgttatcatc acgacgttga
    11161 ttatagtaac tatggatact catattcaac attgacagag ttaccaaatc atgaaattgg
    11221 attgatgttt gaaaaatttg attcatggtc tcgtaatgaa cttcatatga aaaatgttgt
    11281 accatatata acatttaaga ttgaagatct gaaaaagaat taaagctgaa atttgaaaat
    11341 atataaaaag aggataaaaa ttatggtaaa ttacggtatt gttggagctg gatattttgg
    11401 agctgattta gctcgctcaa tgaacaaaat tgaagatgca aaagtggttg cggtatttga
    11461 cccaaatcat ggagaagaag ttgctcaaga gttgggatca gatgtttgtg caagtttaga
    11521 tgaacttgta gcacgtgaag atattgattg tgtgatcgta gcttcaccta gctaccttca
    11581 ccgtgaacca gttgtgaaag ctgctcaaca tggcaaacac gtattttgtg aaaagccaat
    11641 tgcattgtct tatgaagatt gtaaagccat ggttgacgca tgtaaagaaa ataatgttat
    11701 ctttatggct ggtcacatca tgaacttctt taacggtgta caccatgcta aagaattgat
    11761 tactcaaggt aaaatcggta aagttcttta ttgccatgcc gctcgtacag gttgggaaga
    11821 acaacaacca actgtatcat ggaagaaact tcgttctcaa tctggaggac atttgtacca
    11881 tcatattcat gaattagatt gcattcagtt tatcatggga ggacttcctg aaaaagcgac
    11941 aatggtagga ggcaatgtat atcataaagg tgaaaacttt ggtgatgaag atgatatgct
    12001 cattgtaaac ttagaatact ctgatgatcg ttatgctgtt ttggaatatg gtaatgcttt
    12061 ccgttggggt gaacactacg tcttgattca aggaactgaa ggagctatca aacttgattt
    12121 gttcaatact ggaggtactc ttcgtgttaa aggtgaagga gaatcacact tcttagttca
    12181 tgaaactcaa gaggaagatg atgaccgtac agctatctat accggtcgtg gtatggatgg
    12241 agcaattgcg tacggtaaac caggagtacg ttgcccatta tggttgcaaa catgtattga
    12301 taaagaaatg gaatatctac atgacatcat taaaggtgga gaaattacag aagaatatga
    12361 aaaacttctc aatggtgtag ctgctttaga atcaatcgct accgctgatg catgtacttt
    12421 atcagttaaa gaagatcgaa aagtaagtct ttcagaaatc acaaatgctt aacttttgta
    12481 aaacagaata gtaaattctt atcattatat aatttctaaa gttctgtgat acaactcatt
    12541 gaataaagaa atagagatgg gactgggata atgcccagtc ccatttttta tcaaaaagta
    12601 atgagatcaa aaatgtggga gtgatgaaat gaagattata gggatcgata ttggcggaac
    12661 aacaattaaa gcagatttat acaatgagtt tggaacgagt ttaaatcagt tcaaagagat
    12721 agaaacaatt attgactatg atttgggaac gaaccagata ttaaatcagg tctgtgattt
    12781 aattggtgag tatattttaa atcattcaat tgatggtgtt gggatttcca ctgctggagt
    12841 tgttaatgct aatacaggag agatcatcta tacaggctat acaataccag ggtatatcgg
    12901 agtaaacttt actttcgaaa tagaaaaacg ttttgggttg tctacttttg ttgaaaatga
    12961 tgttaattgt gctgcattag gtgaattgtg gaagggacaa gccaaagata agaaaaatgt
    13021 agtaatggtt actattggaa caggtatagg aggcagtatt attgtcaatg gacaaattgt
    13081 taacggattt aactatactg ctggtgaagt aggctatatt cctgtaggta attcggattg
    13141 gcaaagcaaa gcctcaacaa ccgcattgat tcatttatat caaaagaaaa gcttgaaaac
    13201 taatcaaact gggcgtactt tctttactga tttaagagct ggagataaag tcgctaaaga
    13261 aacttttgaa atttttgtag aaaatctaac aaaaggttta ttaacgatta cttatctact
    13321 taatccagaa attctcatat taggaggtgg gatcctggct aaaaaggata ttttgttacc
    13381 tgaaattcaa agttctttag ctaaaaatgc aatggataat aggtttttgc ctaaaaatct
    13441 tgtggcagct acattaggaa atgaagctgg tcgtatagga gctgtaaaaa atttcttaga
    13501 tagaatttct aataaatagt atgaaagata aggaggtgtc acaatgacta actctgtatt
    13561 ttcgacaatg caagatattg agaatgttgc aaccgatatt ataaaatcat atgataatga
    13621 gatttatact tataaagctg tttcccaaga agaattggaa aaactagaaa aaagttatga
    13681 tgaaaaaagt cacgaagaat tagtttcaat agaaagcaat ttagaaatga aacaacagaa
    13741 ccttattgat gaggttaata aaacaatcaa ggaaaattat gaaaagattc agtatatttc
    13801 atcaagtagg agaggagaat ttgtagaaaa aattattggt agggtggtag aaaaatatgg
    13861 ctattagtca gatgaaaaga atttctctac tattttctaa aagtagtctt gatgatgttt
    13921 taaaaactat tcaagaacta gagtcagtgc agttccgtga tttaaaggtt taggataact
    13981 ggtcagaagc tctagaaaaa gatgaggttg tatttccaac tattcaaatt tctcatactt
    14041 ctaattccaa tcatggggtt attgaaggaa atgatgcctt gatttatttg atgaatcaac
    14101 aacaatattt agaagcaact gtagagaaat tacaagaata cctaccgaaa gaaaacacgt
    14161 ttaaattatt acagcaacct ccgataacga cctcttatga agaattagaa aaatttggta
    14221 aagctaatgt tgctgagggt gttcttaaaa aagtgaatcg tcaaataaac agagttcatg
    14281 aattagaaag acacattcaa agtaataatg aggaaataga gagattaata aaatgggaaa
    14341 aattagaaat tattcctgcg catttagaac aatttttttt ctgtaaagga aaagtcggaa
    14401 caattccaag gactgtagat aatcgcttat acaatagttt tttagaaaac aatattgaag
    14461 ttcaagaaat attttctaat gatagagagt acggtgttgt tgttttctat cagtccagtt
    14521 gctctattga ttttgatgaa tacttatttg aaccatttga ttattctaga aaggaattac
    14581 cgaagcagcg agtagtagat ttggatcaag aaaacatgca gttaataact gaaaaagaga
    14641 atattatcgc atcgttgcaa gattcaaaga ataatttgat agatttacaa tggcaaattg
    14701 actatatttt atctatctat gctcgtcaaa tctctaagaa taaccttttg agcactccgc
    14761 atctagttgc actagaagga tggatagaag aaactcgt
//
LOCUS       DAVBIC010000052        14254 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.052, whole genome shotgun sequence.
ACCESSION   DAVBIC010000052 DAVBIC010000000
VERSION     DAVBIC010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14254)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14254)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14254
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.052"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            3..350
                     /locus_tag="VQ664_001721"
     CDS             3..350
                     /locus_tag="VQ664_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789840.1"
                     /translation="MLRLPYKKQKISHFTVSEDKDICRYIRQQLYYQNLFWMKEQAEA
                     YQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPP
                     AFYQQYFLKNMVE"
     gene            369..2171
                     /gene="pepF"
                     /locus_tag="VQ664_001722"
     CDS             369..2171
                     /gene="pepF"
                     /locus_tag="VQ664_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HET2789841.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEVLKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQMEKLYVYAHMKNDQDTREAKYQEYYAKAMTFYSQL
                     DQAFSFYEPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGIYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFTYQEALKKAEDALAVLGEDYL
                     SRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            2173..2886
                     /locus_tag="VQ664_001723"
     CDS             2173..2886
                     /locus_tag="VQ664_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HET2789842.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGFLKELENFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQKLFDATLDNPELTATLVPLG
                     DGILMLRKNVADVQLSESE"
     gene            2953..3894
                     /gene="prsA"
                     /locus_tag="VQ664_001724"
     CDS             2953..3894
                     /gene="prsA"
                     /locus_tag="VQ664_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HET2789843.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFY
                     EQVKNNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(4011..4352)
                     /locus_tag="VQ664_001725"
                     /pseudo
     CDS             complement(4011..4352)
                     /locus_tag="VQ664_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            4765..4860
                     /locus_tag="VQ664_001726"
                     /pseudo
     CDS             4765..4860
                     /locus_tag="VQ664_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(5113..5733)
                     /locus_tag="VQ664_001727"
     CDS             complement(5113..5733)
                     /locus_tag="VQ664_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HET2789844.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPESIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLYTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTLNTWNDTSYQS"
     gene            complement(5733..6215)
                     /locus_tag="VQ664_001728"
     CDS             complement(5733..6215)
                     /locus_tag="VQ664_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HET2789845.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKDLEKTTGYIHGANN
                     PVGIRQKHNYPIFIDKIALDLDRMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            complement(6215..7057)
                     /locus_tag="VQ664_001729"
     CDS             complement(6215..7057)
                     /locus_tag="VQ664_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HET2789846.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDLKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDLLGTFFPIGIGAGATLIVFSKLMDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            complement(7152..7952)
                     /locus_tag="VQ664_001730"
     CDS             complement(7152..7952)
                     /locus_tag="VQ664_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HET2789847.1"
                     /translation="MRKQIHPLILFSFFGIMMFILIINRPLNDSQSFKTKSNIAQIEA
                     QALKHLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDK
                     AYKSHITELQKRNVPVAVYAYVAGKSVQEMEKAAEVFYNAASPYSPSYYWLDVEDKTM
                     SNMNEGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPSYGSDSGFLES
                     SPKTDLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            8096..9475
                     /gene="glmU"
                     /locus_tag="VQ664_001731"
     CDS             8096..9475
                     /gene="glmU"
                     /locus_tag="VQ664_001731"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HET2789848.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAGQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIAPEVQIEA
                     NVTLKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPKNQ"
     gene            9485..10030
                     /locus_tag="VQ664_001732"
     CDS             9485..10030
                     /locus_tag="VQ664_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET2789849.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTARRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELQKK"
     gene            10042..10356
                     /locus_tag="VQ664_001733"
     CDS             10042..10356
                     /locus_tag="VQ664_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="foldase"
                     /protein_id="HET2789850.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKDHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            10373..11065
                     /locus_tag="VQ664_001734"
     CDS             10373..11065
                     /locus_tag="VQ664_001734"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HET2789851.1"
                     /translation="MKIGIIAAMPEELAYLVQHLDNTQEQVVLGNTYHTGTIASHEVV
                     LVESGIGKVMSAMSVAILADHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHALNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLTFLKALD"
     gene            11142..11633
                     /gene="rocS"
                     /locus_tag="VQ664_001735"
     CDS             11142..11633
                     /gene="rocS"
                     /locus_tag="VQ664_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HET2789852.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            11731..12321
                     /locus_tag="VQ664_001736"
     CDS             11731..12321
                     /locus_tag="VQ664_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HET2789853.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAE
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGVLDLSQLFD"
     gene            12330..14093
                     /locus_tag="VQ664_001737"
     CDS             12330..14093
                     /locus_tag="VQ664_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HET2789854.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINLLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFGFMKKLTCAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDKYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASLFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMNRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQEDPEYTDLLLKKALEFFEF"
BASE COUNT         4485 a         2552 c         2969 g         4248 t
ORIGIN      
        1 aaatattgcg tcttccctat aagaaacaaa aaatatctca ttttacagtt tctgaggaca
       61 aggacatctg tcgctatatc cggcaacaac tttattatca aaatctcttt tggatgaaag
      121 aacaagcaga agcctatcaa aagggagaaa atatcctgac ttatggactg aaagaatggt
      181 atccacaaat tcgaccaata gtgggcaaat ttttccagat tgaacaagac ttgactagct
      241 attatcagca cttttatacc tattaccaaa aaaatcctca aaatgattgg caaaagcttt
      301 atccaccagc cttttatcag caatatttct tgaaaaatat ggtagaatag aaaggatgga
      361 ggaatctaat ggtattacaa agaaatgaaa taaatgaaaa agatacatgg gatctatcaa
      421 cgatctaccc aactgaccag gcttgggaag aagtcttaaa agatttaaca gaacaattgg
      481 agacagtagc ccagtatgaa ggccatctct tggatagtgc ggataaccta ctagaaatca
      541 ctgaattttc tcttgaaatg gaacgccaga tggagaagct ttacgtttat gctcatatga
      601 agaatgacca ggatacacgt gaagctaagt atcaagagta ctatgccaag gccatgacat
      661 tctacagcca gttagaccaa gccttttcat tctatgagcc tgaatttatg gagattagcg
      721 aaaagcagta tgctgacttt ttagaagctc aaccaaagct gcaggtttat caacactatt
      781 ttgacaagct cttgcaaggc aaggatcacg ttctctcaca acgtgaagaa gaattattgg
      841 ctggagctgg agaaatcttt ggttcagcaa gtgaaacctt cgctatcttg gacaatgcgg
      901 atattgtgtt cccttatgtc ctagacgatg atggtaaaga agttcagcta tctcatggga
      961 tttacacacg tttgatggag tctaaaaaac gtgaggttcg ccgtggtgcc tatcaagctc
     1021 tttatgcgac ttacgaacaa ttccaacaca cctatgccaa aaccttgcaa accaatgtta
     1081 aggtgcaaaa ttaccgtgct aaagttcgta actacaagag tgctcgtcat gcagccctcg
     1141 cagcgaattt tgttccagaa agtgtttatg acaatttggt agcagcagtt cgcaagcatt
     1201 tgccactctt acatcgctat cttgagcttc gttcaaaaat cttggggatt tcagatctca
     1261 agatgtacga tgtctacaca ccgctttcat ctgttgaata cagttttacc taccaagaag
     1321 ccttgaaaaa agcagaagat gctttggcag tcttgggtga ggattacttg agccgtgtta
     1381 aacgtgcctt cagcgagcgt tggattgatg tttacgaaaa tcaaggcaag cgttcaggtg
     1441 cctactctgg tggttcttac gataccaatg cctttatgct tctcaactgg caggacaatc
     1501 tggacaatct ctttactctt gttcatgaaa caggtcacag tatgcattca agctatactc
     1561 gtgaaactca gccttatgtt tacggagatt actctatctt tttggctgag attgcctcaa
     1621 ctaccaatga aaatatcttg acggagaaat tattggaaga agtggaagac gacgcaacac
     1681 gctttgctat tctcaataac ttcctagatg gtttccgtgg aacagttttc cgccaaactc
     1741 aatttgctga gtttgaacac gccattcacc aagcagatca aaatggggag gtcttgacaa
     1801 gcgatttcct aaataaactc tacgcagact tgaaccaaga gtattatggt ttgagtaagg
     1861 aagacaatcc tgaaatccaa tacgagtggg ctcgcattcc acacttctac tataactact
     1921 atgtatatca atattcaact ggctttgcgg ccgcctcagc cttggctgaa aaaattgtcc
     1981 atggtagtca agaagaccgt gaccgctata tcgactacct caaggcaggt aagtcggact
     2041 atccacttaa tgtcatgaga aaagctggtg ttgatatgga gaaggaagac tacctcaacg
     2101 atgcctttgc agtctttgaa cgccgtttaa atgagtttga agcccttgtt gaaaaattag
     2161 gattggcata aaatggttga atcgtatagt aagaatgcta accataacat gcgtcgtcct
     2221 gtcgtcaaag aagaaattgt agacttgatg cgtcagcgtc aaaagcaggt cacaggtttc
     2281 ttgaaagaat tggaaaactt tgcccgcaag gaaaatattc ctattattcc ccatgaaacg
     2341 gttgcttatt tccgttttct tatggaaacc atgcagccta aaaatattct ggaaattggg
     2401 acggctatcg gtttttcagc tctcttgatg gctgaacatg cgccaaatgc taagattaca
     2461 actattgatc gtaatccaga aatgattggt tttgccaagg aaaattttgc ccagtttgac
     2521 agtcgcaagc aaatcactct cctagaggga gatgcggtgg atgtcttatc tacactgaca
     2581 gagtcttatg atttcgtctt tatggattct gccaagtcta aatacatcgt ctttctgcca
     2641 gaaatcctca aacatttgga agttggtggt gtggttgtct tggatgatat ttttcaaggt
     2701 ggtgatgttg ccaaggatat tatggaagtc cgtcgtggtc agcgaaccat ttatcgaggc
     2761 cttcaaaaat tatttgatgc aaccttagac aatccagaac tcaccgcaac attagtgcct
     2821 ttaggagatg gtattctcat gcttcgtaaa aatgtagcag atgttcaact gtctgaaagc
     2881 gaatgatttt cagaaaaatt taagaaaaaa tagtaaaata gatagagtaa cacttatctc
     2941 aaaggagtag acatgaagaa aaaattattg gcaggtgcca tcacactatt atcagtagca
     3001 actttagcag cttgttcgaa agggtcagaa ggggcagacc ttatcagcat gaaaggggat
     3061 gtcatcacag aacatcaatt ttatgagcaa gtgaaaaaca acccttcagc ccaacaagtc
     3121 ttgttaaata tgaccatcca aaaagttttt gaaaaacaat atggctcaga gcttgatgat
     3181 aaagaggttg atgatactat tgccgaagaa aaaaaacaat atggcgaaaa ctaccaacgt
     3241 gtcttgtcac aagcaggtat gactcttgaa acacgtaaag ctcaaattcg tacaagtaaa
     3301 ttagttgagt tggcagttaa gaaggtagca gaagctgaat tgacagatga agcctataag
     3361 aaagcctttg atgagtacac tccagatgta acggctcaaa tcatccgtct taataatgaa
     3421 gataaggcca aagaagttct cgaaaaagcc aaggcagaag gtgctgattt tgctcaatta
     3481 gccaaagata attcaactga tgaaaaaaca aaagaaaatg gtggagaaat tacctttgat
     3541 tctgcttcaa cagaagtacc tgagcaagtc aaaaaagccg ctttcgcttt agatgtggat
     3601 ggtgtttctg atgtgattac agcaactggc acacaagcct acagtagcca atattacatt
     3661 gtaaaactca ctaagaaaac agaaaaatca tctaatattg atgactacaa agaaaaatta
     3721 aaaactgtta tcttgactca aaaacaaaat gattcaacat ttgttcaaag cattatcgga
     3781 aaagaattgc aagcagccaa tatcaaggtt aaggaccaag ccttccaaaa tatctttacc
     3841 caatatatcg gtggtggaga ttcaagctca agcagtagta catcaaacga atagtccaaa
     3901 tcaatgagtc agggaaaaaa actcgacttc aggaaaaaat gaagcaaaca ttcccacaat
     3961 aaaacgcata gtacaaggtt tgtactgacc ccaaaagtta gacaattaat ttatctgaag
     4021 gatttagttc tgtattgcac agggctaagt ccttttagtt ttaccttaat tctcttattg
     4081 ttgtaataat caatatagtc tataatggct tgttccaatt gattaagtga tttaaatgtt
     4141 ttctcatagc cataaaacat ttcggatttt aaaatgccaa agaaagattc catcctaccg
     4201 ttgtcttggc tgtttccttt gcgtgacata gatgcttgaa ttcccttact ctctaggaag
     4261 cgatgataag aatcgtgttg gtattgccag ccttggtcac tatggagaat cgtattctcg
     4321 tagtgcttct ctttgaatgc ctgttccaac attaacgatc aatcaattta atcatgtacc
     4381 taatattaga attgtttatc ccaaatttat ttgaaagctt ctctaagcta tatccttgtt
     4441 ttctaagttc atagatctga actttatcat cataagttaa tttcataata aaaacacccc
     4501 aaaagttaga ttttttctgt ctaacttttg gggtgtagtt catgtacacc tgatatgatg
     4561 cgttttataa ttttaaagac tttttgacca gcctcatttt tttaacttga tactcagtga
     4621 aaagcaaaga ttaaactagg aagctagctg taggctgctc aaagaacagc tttgaggttg
     4681 cagataaaac ttgtgaggtc accaacatat ataatgtgaa gctgacgtga cttgaataga
     4741 ttttagaagg gtatgagtct ggaagtttta atggataatg caagattcca tagaatgggt
     4801 aagctagagt tcttatgtga agagtttggg cataaacttt taccttttcc tccctactca
     4861 tcttagtata gaaaagtgaa tctaaaatag tacataactg cttctaaaac attcttataa
     4921 attgatttaa attctcaaat catattattc agttcttatt tcattttgct ctacaatcct
     4981 gttgagaaga cacgtgttca tatcaaaaag gtattggcaa gttgcaatac ctttttacaa
     5041 ggttcttttg tcttattttt gtttcaactg actatatctc ctatggttct agttcagaag
     5101 gctaggctat aattatgatt gataagaagt atcattccaa gtattgagag tgaatgtttc
     5161 aaaatcatgg gtttctataa tggtcaggct ggcatttgct agaccgccat ctttacgaag
     5221 aagtggttct ttatagccta ggagagtacg aagactggca gtaagattgg cgccgtgtcc
     5281 gacaattaga atacgctcag ctggactatc ttttaatgat ttgataaatt ggatggtccg
     5341 ttgagttgta ctatagaggg attcggctcc gaacattcga gtgtcaaatt gagcaagatt
     5401 tgaacgaaaa gcctggattt gttgcgggta aatagcttcc aaggttgcaa ttttcaaacc
     5461 ttctaacttc ccaagttgcc attcacggag attaggaacg atttctaaag aacagggggt
     5521 atagagttga ctttggataa tctcagcaga tttgaccgct cgaggtaaat cacttgaata
     5581 aatctgatca aaaggaattt ccttgagata ctggccaagt cgttttaggg tttcaatgga
     5641 ttcaggaaga agaggagaat caccgctagc accttgaaaa cgaccttctt ggttccagag
     5701 ggtacgaccg tggcggacaa agtagagttt cattacttga tgtcctccaa aatatctaca
     5761 aagtctgcct ttacaaagct agccaagtct tgtggcgcga cgataatgct gtgtccgact
     5821 tcgcctgcag agacaatcat tcgatccaaa tctagagcaa ttttatcgat aaaaatggga
     5881 taattgtgtt tctgacgaat tccgacagga ttattggctc catgaatgta accagttgtt
     5941 ttttctaagt ccttttgtgg aatcatgctc acttttttat tgccagaaat tttagctagt
     6001 ttcttttcag acaagtgctg agtgataggg acaattccga taatcggtcc ggtcttgtct
     6061 cccaaaagcg ccaaggtttt gaaaatctga tctcgttcat aaccttgagg aagctctcct
     6121 tctagggcat tgatttgaat cccctgatga gggatagctg ctttagatag gatttgttcc
     6181 accaatgttt ttttgatttt aacttttttt gccattattt atatttatcc tccaattgac
     6241 tcatccaaat accaagccag attcccagcg caaagaagaa ggcgatgatg acataaccga
     6301 caagtgaaag tcctgtgtat tggatacttt cagcgtttcc tgcatttgga attaagatca
     6361 aaagggtact tgataggacg ataccgatga tgaaatgata gacgcgtgag tggtagttgt
     6421 ttaaggcata atccatcaat tttgaaaaaa cgatgagagt tgcacctgca ccaattccaa
     6481 tcggaaagaa ggttcccaag agatcaaaag ttttaaaacc agtcaacata ggagcataga
     6541 gtcccaaaat caaaagtaag ttcgatgggc tgaggccagg aaccaagacg ccaagggcca
     6601 atagtgcgcc tgctaggacg aagttaagaa agctggcgct taaggttcca acgacaaaat
     6661 ttaaggcata gagtcctaat ccagaaatga taaaggttgt ccataaccaa gctaaatcaa
     6721 tcttgtctcg gtcagattct cgagttgatt ctttgaggag gctaggaact gtaccgataa
     6781 tagctcccgc aaagctccat aatacaaaga cctgataatt ttcaagcagg tattcaatcg
     6841 ggtaggaaaa taagccgatt cccagaagca taccgatggc aactggaata aagtacaaaa
     6901 cattttcttt aaggtcttta aagggatggg ccagaaagcc aatcattcgt tcatagattc
     6961 ctaagattgc tgctagaacc cctccggaaa ttcccggtag gataaatcca agagcaatta
     7021 caatcccttt aataacgcgt gctaaccatg agagcatata tttcctccaa ctatttctat
     7081 ttcaaaaatt ccttactata ttgtatcaca atcagacaca aaaagaaaaa gcaaatgata
     7141 aacaaatgct tttaaggttt taaaaaaagt tttcgaaagg tttcttcttt attttttaag
     7201 ggagagataa cgttgatatc taaatcgtgg tcaaagccgg caatttttcc tttagatgtg
     7261 tattggtgaa tatcataatc taaatcagtt ttaggactgc tctccaaaaa tcctgagtct
     7321 gagccgtagg acggaatcca aacagaggta aacttgcctg tatcaatact gtgttcttcc
     7381 atgaagtaga caccaacgta gatgccgatg tttttagcac ctagtgatgc tagttttgct
     7441 cgaaagtttt cgacaccttc gttcatatta gacatggttt tgtcttccac gtcaagccaa
     7501 tagtaactag ggctgtaagg agaggcagca ttgtagaaaa cttcggcagc cttttccatt
     7561 tcttggacac tttttccagc tacataagcg tagacagcaa ctgggacatt ccgcttttga
     7621 agttcagtga tatgactctt ataggccttg tctattccat tgataaatga agcatcattt
     7681 tcttttgttg tttgagcacc actgtgaaca cgaacaatag cacctgaaat attttgtgag
     7741 agggcatcgt agttgatttc ctcaggacgc tgccagccag agaggtcaat aatcggtttg
     7801 tctaagtgtt tcaaagcctg tgcttcaatc tgtgctatat tggattttgt tttaaacgat
     7861 tggctgtcat taagtgggcg attgatgatt aaaatgaaca tcataatccc aaaaaaacta
     7921 aataaaataa gtggatgaat ttgttttctc atatcttata agtctaccct aaaaatcaaa
     7981 aaaaatcaaa aaaatgggtt aaggaagaga ctttagagca ttttttcatt caagagtgcg
     8041 gaatgatttg aaatatggta taataaaagg gaatttctac agaaaagaga agattatgtc
     8101 aaattttgcc attattttag cagcgggtaa agggactcgc atgaaatctg atttgccaaa
     8161 agttttgcac aaggttgcgg gtatttctat gttggaacat gttttccgta gtgtgggagc
     8221 tatccaacct gaaaagacag taacagttgt aggacacaag gcagaattgg ttgaggaggt
     8281 cttggctgga cagacagaat ttgtgactca atctgaacag ttgggaactg gtcatgcagt
     8341 tatgatgaca gaacctatct tagaaggttt gtcaggacac accttggtca ttgcaggaga
     8401 tactccttta atcactggtg aaagcttgaa aaacttgatt gatttccata tcaatcataa
     8461 aaatgtggcc actatcttga ctgctgaaac ggataatcct tttggctatg gacgaattgt
     8521 tcgtaatgac aatgctgagg ttcttcgtat tgttgagcag aaggatgcta cagattttga
     8581 aaagcaaatc aaggaaatca acactggaac atacgtcttt gacaacgagc gtttgtttga
     8641 ggctttgaaa aatatcaata ccaataacgc tcaaggcgaa tactatatta cagacgtcat
     8701 tggtattttc cgtgaaactg gtgaaaaagt tggcgcttat actttgaaag attttgatga
     8761 aagtcttggg gtaaatgacc gtgtggcgct tgcgacagct gagtcagtta tgcgtcgtcg
     8821 catcaatcat aaacacatgg tcaacggtgt tagctttgtc aatccagaag caacttatat
     8881 cgatattgat gttgagattg ctccggaagt tcaaatcgaa gccaatgtta ccttgaaagg
     8941 gcaaacgaaa attggtgctg agactgtttt gacaaacggt acttatgtag tggacagcac
     9001 tatcggagca ggagcggtca ttaccaattc tatgattgag gaaagtagtg ttgcagacgg
     9061 tgtgacagtc ggtccttatg ctcacattcg tccaaattca agtctgggtg cccaagttca
     9121 tattggtaac tttgttgagg tgaaaggatc ttcaatcggt gagaatacca aggctggtca
     9181 tttgacttat atcggaaact gtgaagtggg aagcaacgtt aatttcggtg ctggaactat
     9241 tacagtcaac tatgacggca aaaacaaata caagacagtc attggagaca atgtctttgt
     9301 tggttcaaat tcaaccatta ttgcaccagt agaacttggt gacaattccc tcgttggtgc
     9361 tggttcaact attactaaag acgtgccagc agatgctatt gctattggtc gcggtcgtca
     9421 gatcaataaa gacgaatatg caacacgtct tcctcatcat cctaagaacc agtaggagcc
     9481 tatcatggag tttgaagaaa aaacgcttag ccgaaaagaa atctatcaag gaccaatatt
     9541 taaactggtc caagatcagg ttgaattacc agaaggcaag ggaactgccc gacgggattt
     9601 gattttccac aatggggctg tctgtgtttt agcagtaacg gatgaacaaa aacttatctt
     9661 ggtcaagcag taccgcaaag ctatcgaggc tgtctcttac gaaattccag ccggaaaatt
     9721 ggaagtagga gaaaacacag cccctgtggc agctgccctt cgtgaattag aggaagaaac
     9781 agcctataca gggaaattag aactcttgta cgatttttat tcagctattg gcttttgtaa
     9841 tgagaagtta aaactatatt tagcaagcga tttgacaaaa gtggaaaatc cgcgtccgca
     9901 ggatgaggat gaaaccttgg aagtccttga agtgagctta gaagaagcga aagaattaat
     9961 ccaatcaggt catatctgtg atgccaagac aattatggct gttcagtatt gggagttgca
    10021 gaaaaaatag aggaggtcag tatgggtaaa tctttattaa cggatgaaat gattgaaaga
    10081 gctaatagag gcgaaaaaat ttcaggtcct cctttgctag atgataatga ggaaactaag
    10141 attttaccaa cctcttcttc ccgttttggt tatgccaatc ctaaggatca tggttttagc
    10201 caggaaacct tgaagattca ggtcgaacca tctattcata aaagccgtcg tattgaaaat
    10261 accaagagaa atgtcttcaa ttctaagttg aataaaatct tatttgcggt catctttctc
    10321 ttgattttgc ttgttttagc aatgaaactt ttgtaataga aaaggaattg aaatgaaaat
    10381 aggaattatt gctgctatgc cagaagaact ggcttatctg gtccagcatt tagataatac
    10441 ccaggagcaa gttgttttgg ggaataccta tcatacagga accattgctt ctcatgaagt
    10501 cgttcttgta gaaagtggaa ttggtaaggt catgtctgct atgagtgtgg cgattttggc
    10561 tgatcatttc caggtggatg cccttattaa tacgggttca gctggggcag tagcagaagg
    10621 tatcgctgtt ggggatgtcg tgattgctga caaattagcc tatcatgacg tggatgtcac
    10681 agcttttggc tatgcttatg gacaaatggc gcaacaaccg ctttatttcg aatcagacaa
    10741 aacctttgtt gctcaaatcc aagagagttt atctcaattg gaccaaaact ggcatcttgg
    10801 tttgattgct acaggagata gttttgttgc aggaaatgac aagatagaag cgattaagtc
    10861 ccatttccca gaagttttag ccgtggagat ggagggggca gctattgctc aagcagcgca
    10921 tgccctcaat ctcccagtct tagtcatcag agctatgagt gacaatgcca accatgaagc
    10981 aaacatcttt tttgatgagt ttattatcga agctggacgt cgctctgccc aagtcttgtt
    11041 gacctttttg aaggctttag attaagcgga aatttgacag tttttctagc ttatgataag
    11101 atttaagtaa agaaaagcta gaaaacgttt cagaggatat tatgagtatt gaaatgaccg
    11161 tcagtgagat tgcagaggtc ttaggattat ctcgccaagc aatcaataac cgtgtcaaag
    11221 aattaccaga agaagacaca gataaaaatg acaaaggggt aacagttgtt accagaagtg
    11281 gcttgattaa gctagaagaa atctataaaa aaacgatttt tgaagatgag cctgtcagtg
    11341 aagatgtcaa acaacgtgaa ctgatggaga ttctagtgga tgagaagaat gcagaaattc
    11401 ttcgtcttta tgaacaatta aaagccaagg atcgtcagtt atcagaaaaa gacgagcaga
    11461 tgcgtatcaa agaccgtcag attgctgaga aagacaaaca attagatcag caacaacaat
    11521 tgacccttca agccatgaag gatcaagaaa atcttaagct agagctggac caagcaaaag
    11581 aagaagtcca atccactaag aaaggctttt ttgctcgttt atttggagga taatcaagga
    11641 gctgtttagg ttaaatgcta acctgatggc ttcttttgtt tgtgaatagt atagttgatt
    11701 agaacagaga cagtagagga gaggtacaga atggaacgat tagaagatta cattgctttt
    11761 gacttagaat ttaatcagca cgaaggacaa acacacttga ttcaagtatc ggcagtgcgt
    11821 tttagagatg gtcgggaaat cgatgcctat gattcctatg ttcataccag cgtccctcta
    11881 aaaagcttta tcaatggttt gaccgggatt acagctgaga ccttaaaaga tgctcctcca
    11941 gttgagaaag tcttagaaga attccaagag tttgtgggtt ctttgctgat gataggctac
    12001 aatgctgcta aaagtgattt acctatttta gcagagcatg gtttagacta tagccaacag
    12061 tacaaggtgg atttgtatga tgaagctttt gaacgtcgga gttcagattt acatggtatt
    12121 gccaatctca aattgcaaac tgttgcctca tttcttggat ttcaaggtca gtctcataat
    12181 agtttagagg atgctcggat gacggcgcgt gtttacgaat ccttcttaga gtcggatcaa
    12241 gctagggaat tgttagagac agaaagtagc ttatcaaaca atccttttgg tgtcttggac
    12301 ttgtctcaat tatttgacta ggagtgccta tgaaacctga aaaacctaaa aaattgggtc
    12361 ttaaacagat ttacctcaat cttgataaaa tcctctttct atttttcttg atttttatga
    12421 tagtggagta tttgtgggta ccattcaatt catggttggc tagcttctta ttagatcaga
    12481 caggttatct ttttatttcc tataacaatg tcttagccat ccttactcat tctccattga
    12541 ttagtctagc ttttttagcc ttgattgtaa ttaaccttct ggttgcttat tttcaaatag
    12601 gactcctctt tattggtgct cgtcatctcc tctataatga aaagcgaagg ctaattgagt
    12661 atatccgcaa ggttttccat gaaagttttg gatttatgaa aaagctaact tgcgctaaag
    12721 ccttgtttat ctttttctat atagctatgc tttttccttt tatacggaaa atgctgaaga
    12781 tttattatct taataaaatc gtcattccag agtttatcca agcttattta gaagataaat
    12841 attggatgtg gtggctgagc atcctacttc tatctcttat ctttctctat gtctctgtca
    12901 gattgatgtt tgcccttccg aagattgtat atgatcagct gactgttcga gaagcagtga
    12961 tgtttagctt ggagaaaacc aagaagagag ttacttttta tgcttggaat ttattttaca
    13021 tcttgctcaa agcacattta ttattttatc ttcctttgat tcctttatta ttggctcaaa
    13081 ctttggtaga tgatatcact cagagagagt ctctgattct tggtattttg aattttgtcg
    13141 tgattaaaaa tctctattat atggctctga cttatttttt ggttaaattt gtttcatttt
    13201 tgacaggaaa ggagctggat atgcttccta ggagagaaaa agatcacatc gtgcgatggg
    13261 gtgtcatgac ttgtgccagt cttttctttg ccttagaagg ttatatttat ctggaggctc
    13321 ccatggttca tctacctcaa cttatttctc accgaggggt ttccaatgca aatgggattc
    13381 aaaatacagt agagtccttg gaaactacag cacaactcaa accagacttg gtggagacgg
    13441 acgtgcagga aacaaaagat gggcagtttg tcatgatgca tgatgctaac ttgaaaaatc
    13501 tagcaggtat caataaaagt cctcaagact taaacttgga ggagcttaaa gggattgata
    13561 tttttgaaaa tggctaccag actaaaattt caagctttga agattatctc agtcgagcca
    13621 acgaacttgg tcaaaaatta ctaattgaaa ttaaaaccag taaaaaagat agtccagaca
    13681 tgatgaaccg ctttttagcc cgttatgctg caaagctcaa gatttatgga catcaaatcc
    13741 agtctttaga ctaccatgtt gtcgaaaaag taagacagta tgatgccgaa ctgccagttt
    13801 atttcatcat gccctacaat tctgtctttc ctaaaacaag agcgacagga tatactatgg
    13861 agtactcaac cttggatgaa tattttgtaa gcaaactatg gacaacggat cagaaacttt
    13921 atgtctggac tgtcaatgat tcagaagcta tcagcaaatc tcttcactta ggagtagatg
    13981 gagtgattac agatgatttg gaaaaagttc agcgggaaat agaagtagcc caagaagatc
    14041 cagaatatac ggatttgctc ttgaaaaaag cattggaatt ctttgaattt tagtaataaa
    14101 aaagaggaac ggttgttcct cccatgatag gtaagtattc ttgtgaatgc ttgctttttt
    14161 gtggttgcaa tccgtttacg agaattgttt gtattgttct tgtttcaatt tactttatag
    14221 tgctttgaag ttggaatgct acactataac ttct
//
LOCUS       DAVBIC010000053        14039 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.053, whole genome shotgun sequence.
ACCESSION   DAVBIC010000053 DAVBIC010000000
VERSION     DAVBIC010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14039)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14039)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14039
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.053"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            98..1357
                     /locus_tag="VQ664_001738"
     CDS             98..1357
                     /locus_tag="VQ664_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HET2789855.1"
                     /translation="MKVFQHVNIVTCDQDFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPNGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQIQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKVLGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
     misc_feature    1433..1568
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            1607..2107
                     /locus_tag="VQ664_001739"
     CDS             1607..2107
                     /locus_tag="VQ664_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HET2789856.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     gene            2183..2551
                     /gene="rplL"
                     /locus_tag="VQ664_001740"
     CDS             2183..2551
                     /gene="rplL"
                     /locus_tag="VQ664_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HET2789857.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKTKLEEAGASVTLK"
     gene            2738..2908
                     /locus_tag="VQ664_001741"
     CDS             2738..2908
                     /locus_tag="VQ664_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001168336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789858.1"
                     /translation="MQKEGQSSRQFVKSHLMTIMGVDIVKATQLVDEMEQVGLIRFDE
                     FGNVGILVLEGQ"
     gene            2908..3156
                     /locus_tag="VQ664_001742"
                     /pseudo
     CDS             2908..3156
                     /locus_tag="VQ664_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648301.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
     gene            3170..3510
                     /locus_tag="VQ664_001743"
                     /pseudo
     CDS             3170..3510
                     /locus_tag="VQ664_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812122.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            3503..3883
                     /locus_tag="VQ664_001744"
     CDS             3503..3883
                     /locus_tag="VQ664_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HET2789859.1"
                     /translation="MIDLYLSKNRQRNQLLLDFFQNYGIEVSCHSVSEMTKDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFVEIILKNPELTIRLPLAVSNKRVYPSLNLE
                     EARALLPRDTKQLIYMAQTHYLSN"
     gene            3896..4039
                     /locus_tag="VQ664_001745"
     CDS             3896..4039
                     /locus_tag="VQ664_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789860.1"
                     /translation="MAERFWENLSIILAERNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRH"
     gene            4132..4719
                     /locus_tag="VQ664_001746"
     CDS             4132..4719
                     /locus_tag="VQ664_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2789861.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCIGELTILQILYGSSLIS
                     FLWMYGQRKQAHKVNMKSRMKWLGVEFVSLLIISLCFSLIHAQGSTNQANLIGLQHQI
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALAHHTGTILAWCLYV
                     SLGMFLGMVRYKSDLWGSMGLHLVWNLLVYSLLLF"
     gene            4921..5058
                     /locus_tag="VQ664_001747"
     CDS             4921..5058
                     /locus_tag="VQ664_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
                     /protein_id="HET2789862.1"
                     /translation="MAEEVLNLQLVSVQVDETDEVDGMRFSTFSTNRCGNWSAFSWEN
                     C"
     gene            5237..7846
                     /locus_tag="VQ664_001748"
     CDS             5237..7846
                     /locus_tag="VQ664_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000386153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase"
                     /protein_id="HET2789863.1"
                     /translation="MDYNFNLEHPFFFTNNDYSTDTSIKYQVSLPFNWHEVMNNDEWV
                     YQYPIGKFVERQGWKIHISSEYNSSHELLQDVAKICHEMRIPFKHLSTEDKFIMRNGK
                     LVSRGFSGKFITCYPNQNELESVLQRLESALKQYNGPYILSDKRWDEAPIYLRYGVFR
                     PSRDDEKKVAIDELIVGDEVVKDERLPVFKIPKGIVPPDFLNKWLDKKDKKQGDFPFI
                     IDNAIRFSNSGGIYNARLKEDGKKIILKEARPYTGLGFDGTYSSEKLASECKALKILN
                     EWSETPKIYWHGKIWEHTFLGIEHMKGVPLNRWVTNNFPLYEVVDKTKDYLLRVSKIV
                     EKLIDLTNKFHSENVYHQDLHLGNILVKDEDEISIIDWEQAVFSNDEKVVHKVAAPGF
                     RAWRETLPSEIDWYGIRQIAHYLYMPLVTTSDLTYNYVSQTRIEGKKLFESLGYTREH
                     IDYVESLLSYLDSKCPQIENISRKKVLKPMHEIRTIESEQDIQDFIIKLLRGFTLTYG
                     QWRKEFQSRFFPVHYYGLNFNQGIAFSDLAILWSYQQLAKKVKNFKFDDYYEIRTQVI
                     NEAVNNFKKSSLSGLFDGKIGTIWLIYEFGEIDRAVELFTTHFIEIFENSQNKNLYSG
                     QAGILLVGLYFLSKGEIDNKLGEEILIRLREYTLNYIENPETFCKVGASDVQSNDPYE
                     NFGGLLYGHAGVAWLFGEAYKLTGESIYKNGLELAVDKELVAYKVDSNNSLQYSQGHR
                     LLPYLATGSAGLLLLINRNKEILSSKYLKYLTSLERATDVVFCVLPGLFNGFCGLEVA
                     NNIYSDIDDNFSGQKKLIEQLYRYLCVIEEGFVIAGDNGLKITTDIASGFAGVAIGLV
                     SIMDNKLTILPQI"
     gene            7879..9819
                     /locus_tag="VQ664_001749"
     CDS             7879..9819
                     /locus_tag="VQ664_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S9 family peptidase"
                     /protein_id="HET2789864.1"
                     /translation="MNQSNEIFLNTIQEKTHYKRSISSSFQELKKWNSLIFRRGRYWY
                     QFDNWSIPNTGVIKEWYVEDNDWIPKVSSSSLDNSNSLKIVFDVEKYTLPDDSILQDV
                     RISSDESYIVLVVSSLRSTNLIGIKKYTMEELFIIEDISVESSFYLGKFGVMYTRSKE
                     YGRPSKLFYKSFDSFTEEELFEENECSFRLKIVHIDSNNCFVKSVDFQKGRIFLYSFD
                     RTGFVRHSYTETVAPTPRDIALFSTEKAQYFLGLSSTEEKKDQLILRETSSGDRVSIT
                     IPYQDRARRVHCIGRYILLDCSNAANSVFYLATFKNNSLRELSVNKITFDEKTTLYEN
                     SFSDRVLLFLERRTFYEKILSFDLIENTLKTEFERPIIKSNNTKYFSKVIWTKKDSYD
                     VSIPISLFWKSEDTDELPRRKKCILSVYGAYGKNDNSDLDEIMLSIIDAGFIYAIVHV
                     RGGGYLGGEWYRSGKALNKWNSIRDFIEGVNYLRENDVIDSKRLGLITSSAGGIIAGA
                     VLNEEKNLLQSILLFSPFINPYDTLQNPNDPLSKTEIAEWGDIRDPEVKAYIKSYSPM
                     QNIEKARDSNTVIVNILGEKDPYINNNEVIEWSKKLNSIGVKSLLYLNKAAGHGGFTP
                     SDVLLMIDTLNYFFEEVGRNNL"
     gene            9816..11423
                     /locus_tag="VQ664_001750"
     CDS             9816..11423
                     /locus_tag="VQ664_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2789865.1"
                     /translation="MNYLKFIKKTKLILMGILIFLSSFNGVLLSGIIVYAGSLNQTSS
                     FSDVLRFGAISILGWSAIYISNYYLEVTEASITKDINVKIKQGYFREQYLSSEMVKDY
                     SSIISVLSNDLRLIEENYFRQIFEIISSILLFIVSLSFMLYLNFLVSIIFIVLSALPI
                     IVPVFMKKMLSNSANEYSNSNAEYTHIIKEIFNGFKTLKSYSVTKEIISLSDKKLDKL
                     EDSTFNLKRSEVLSKLVAVLISGFCFLVPLVVGCYFVIYHKSLSFSELIGIFLANDKV
                     LGPIQSIAYSLNKINTTKDLRKPFLKYLSGEKNFIDAEHDNNGLYTSSIDEIHMKDVV
                     YSITPENKLSIDFSFKSPFRVLLTGTSGSGKTTILNLINGSLKPQKGYVNLLSHGKKS
                     SDSIPTVDQTPYIFDTTIRENVTLFQNEYFSDDQIIEVLKKVNLYEELEKIDILNYQC
                     GENGSNLSGGQKQKIALARALIRNNKVYLFDEISANLDNDNSNSIHDILFNLGISFIE
                     VSHHYDLNDKRYTDIYKLENGTLFKIK"
     gene            11438..12178
                     /locus_tag="VQ664_001751"
     CDS             11438..12178
                     /locus_tag="VQ664_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2789866.1"
                     /translation="MDKDYILKVKGLYHQFLLGNNKTLQVLKNVSLSASRGEFISILG
                     ISGSGKSTLLKCISSLLEPTSGEVILNGINPYKIRNAKLSSIRRNEVSFIFQAYNLIP
                     SLPVIENIALPLRLSQKKLTIKNVENLLKRMKFNAGLNDFVGTLSGGEQQKVAIARAV
                     IADSDIIFADEPTGALDSVSREVIFELLRELVGAGKCVIMVTHDIELASKTDRALILK
                     DGKIFKELHRPSGEELYKILEVQSTTEE"
     gene            12181..13500
                     /locus_tag="VQ664_001752"
     CDS             12181..13500
                     /locus_tag="VQ664_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789867.1"
                     /translation="MLRLVYYQFLHNKKQWLGVSPVIFVSSLVMGLAVNGVINVENNS
                     QVFVGLPDPKPIFMFPIVFGGVTLFFVLSNIINMLVEIFRDDYELLEVLGASLLQLSF
                     LVGGQIFIISSIISFIAYLCSIFVTSNYYYFLQYFFGENILPDIQFQTSAVGCIITVV
                     LISFLAFLSGCFYTFKKIRNRKSSKIRHVLSIVKRILLLAGFSVIWLLSLQQIFQDST
                     ILAKAQIIFNIVILDIVIIYQLSPFIQSCFIKLLSIIIFRNNFMFIASKWNLLYRKPY
                     IKSISAAITGAILLISSFQMISQNILSQFQDDSDLELKVAFIVYVGAPILIVLANIIS
                     IAFLSSHQERIEIQQFEILGTSNYQMVKIKVGEAIFLTFVTSLIAFLLNIKIMALIYY
                     SLEDVLIDDMNLLGLILPNFIVSIILFILIFITKSSYFIFKNAKIIS"
     gene            13634..13771
                     /locus_tag="VQ664_001753"
     CDS             13634..13771
                     /locus_tag="VQ664_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
                     /protein_id="HET2789868.1"
                     /translation="MAEEVLNLQLVSVQVDETDEVDGMRFSTFSTNRCGNWSAFSWEN
                     C"
BASE COUNT         4691 a         1960 c         2777 g         4611 t
ORIGIN      
        1 agatagaact gacgaagtca gtaaccacac ctacggcaaa gtgaatctga agtggtttga
       61 agagagtaca acttgtcttt tagaaaagga gcctataatg aaagtctttc agcatgtaaa
      121 tatcgtgact tgtgatcaag atttccatgt ttatcttgat ggaatcttag cagtcaagga
      181 ttctcaaatc gtctatgtcg gtcaagataa gccagcgttt ttagagcaag ctgagcagat
      241 tatagactat cagggagctt ggattatgcc tggtttggtc aattgtcaca cccattctgc
      301 aatgacaggt ctgagaggga tccgagatga cagcaatctc catgaatggc tcaatgacta
      361 tatctggcca gcagaatctg agtttactcc cgacatgact accaatgcgg tcaaagaagc
      421 cctgacagag atgctccagt caggaacaac aacctttaac gatatgtata atcccaatgg
      481 tgtggatatc cagcaaattt atcaggtggt gaaaacttcc aagatgcgtt gttatttttc
      541 tccgactctc ttttcttcag agacagaaac aactgctgag actataagca gaactcgatc
      601 catcatagac gaaatcttaa aatataaaaa tccaaatttc aaggttatgg tagcacctca
      661 ttctccgtat agctgcagta gagacttgct ggaagcgagt ttggaaatgg caaaagagct
      721 aaatattccg ctccatgtcc atgtggcgga gaccaaggag gagtcaggaa ttatcctcaa
      781 acgatacggc aaacgccccc ttgcttttct tgaagaactg ggttatttag atcatccgtc
      841 cgtatttgct cacggggtcg aattaaacga gagagaaatt gaacgcttgg catcttctca
      901 agtggctatc gcccacaatc ctatcagtaa cctcaaactg gcatcaggaa ttgctccaat
      961 tatccagatc caaaaagcgg gagtagcagt cggaattgcg actgactcgg ttgcttccaa
     1021 taacaatcta gatatgtttg aggaaggaag gactgcagct cttcttcaga agatgaaaag
     1081 tggggatgcc agccagtttc caatcgaaac agctctcaag gtactgacaa tcgaaggggc
     1141 taaggtcctt ggaatggaaa atcagatagg aagtctggaa gtcggcaagc aagcagattt
     1201 tctggtcatt caaccacaag ggaaaattca tctccaacct caggaaaata tgctgtctca
     1261 cctggtttat gcagttaaat ctagtgatgt agatgatgtt tatatcgccg gagaacaggt
     1321 tgttaagcaa ggtcaagtcc tgacagtaga actttaaaag aaaaatcacg aaaaatttta
     1381 aaaaaagttt gcaaaaatct tgcattcttt ttttgactat gctatactta tatacggttt
     1441 aaaaaaactg cctaagacag taggggagct cgactcataa atatcctacc gaggacaaga
     1501 cgtatcatgt aaaaagaagc gtattgtact ttcgtgtcta ggtttgggcg cgtttttctt
     1561 tttgaaaaat tccccaagca aaataattac ggaggtgaac acactaatga gtgaagcaat
     1621 tattgctaaa aaagcggaac tagttgacgt agtagctgaa aaaatgaaag ctgctgcatc
     1681 tatcgtcgtt gtagacgctc gtggtttgac agttgagcaa gatacagttc ttcgtcgcga
     1741 gcttcgtgga agcgaagttg agtataaagt tattaaaaac tcaatcttgc gtcgtgcagc
     1801 tgaaaaagct ggtcttgaag atcttgcatc tgtatttgtt ggaccatctg cagtagcatt
     1861 ttctaatgaa gatgttatcg caccagcgaa aatcttgaac gacttttcta aaaacgctga
     1921 agcacttgaa attaaaggtg gtgcaatcga aggcgctgtc gcatctaaag aagagattct
     1981 tgcacttgca actcttccaa accgcgaagg acttctttct atgctccttt ctgtacttca
     2041 agcgccagtg cgcaacgttg ctcttgcagt caaagcggtt gcagaaagca aagaagacgc
     2101 ggcttaatct taagctacac agcgtagcct agctacgaaa aaaactatta taaaatttaa
     2161 aacttatttg gaggaaataa caatggcatt gaacattgaa aacattattg ctgaaattaa
     2221 agaagcttca atccttgaat tgaacgacct tgtaaaagct atcgaagaag aatttggtgt
     2281 aactgcagct gctcctgtag ctgttgctgc agctgatgca gctgatgctg gtgctgctaa
     2341 agattcattc gacgttgaat tgacatctgc aggcgacaaa aaagttggcg ttatcaaagt
     2401 tgtacgtgaa atcactggtc ttggtcttaa agaagctaaa gaacttgttg acggtgcacc
     2461 agcacttgtt aaagaaggcg ttgcaactgc agaagctgaa gaaatcaaaa ctaaattgga
     2521 agaagctgga gcttcagtta ctcttaaata atagagtatc gcaatttgat tgcggaatcc
     2581 ctatttacca gtctttgaga gcgataagcg attgatagaa actgataaat tgatttggtt
     2641 tcctgccaaa aattctttgg caggattttt gttttaataa actttcgggg gtagacacta
     2701 gattgtctac cccttttttt gtgtttcgga ggtaattatg caaaaggaag gacagtcatc
     2761 acgtcaattc gtgaagagtc atctcatgac tatcatggga gttgatattg taaaagcaac
     2821 tcagttagtt gatgaaatgg aacaagtagg tttaatccga tttgatgaat ttggaaatgt
     2881 tggaatttta gtcttggagg gacaataatg aagtgtatta ccgctaatca atatcagaca
     2941 tcagagcgtt attataagct ccccaaactt ttatttgaga gtgaacggta taagaatatg
     3001 aaactggagg ttaaggtggt ttactcagtt ttaaaagatc ggttggagtt gtctttgagc
     3061 aaaggttgga ttgatgagga tggggctatt tatttgattt attccaattc aaatttgatg
     3121 gcacttttag gctgttcaaa gtcaaaatta ctctccatgt gagtttgaag tgacattttt
     3181 agatgattac cataaaaaac ataactaccc actattttac gaatcctatc ttcaaaacgt
     3241 tatggaattc cttgaaagtc aagacataaa gaatggggtt gatgcctttg tagatgatca
     3301 tcaaaatctc gtttttgttt tatatggaca aggctatcga gccgagggaa aagagggaat
     3361 acttacaacc caagtaactg taaaagctta tgatgaagac aagaaaccga ttaacttcgc
     3421 aaatttatta gattccttaa tttattagat tccttaatcg tgtcagaata tcaaatggaa
     3481 ccgaatcttt gggaggtctc ccatgattga tctctatcta agtaaaaata gacaaagaaa
     3541 tcaacttctt ttagatttct tccaaaacta tggcatagag gtatcttgtc attcagtttc
     3601 tgaaatgaca aaggacaaat taattgagat gatgagctat tcttcagatt gttttgagtt
     3661 tttatctccc aatttattac gatttaagaa ccgtgacaat ctaagattaa cggatttcgt
     3721 tgagataatt ttaaaaaatc ctgaactaac catcagactt cctcttgcgg tttcaaataa
     3781 gcgagtttat ccaagtctga atttggaaga ggctagagct ctattgccaa gagatacgaa
     3841 acaattgatt tacatggcgc aaacacatta tttatctaac taaaggagaa gcaatatggc
     3901 tgaacgattt tgggagaact tgtccattat tttggctgaa agaaatatca gctggattga
     3961 gttaaccaga aaaatgtttg cgggagagtt tcactatcca agtgaattga atcgtttgta
     4021 tcaaaagatt cgccactaga agatggaaca atgaatgcct caaagtccat gggtagaaag
     4081 gattgtgcag gtattagatt tagattatga agatttattt cggaggtaac tatgaaaaga
     4141 ataattccag tttatatatt ccaacaagta aatgtcctat tggtatctct atacttattg
     4201 aaatttcttt gtatcggtga gttaactata ctacagattc tctatggttc gtcactcatt
     4261 tcttttttat ggatgtatgg ccaacgcaaa caagcgcata aggtcaatat gaaatctagg
     4321 atgaaatggc ttggtgttga atttgttagc ctactgatta taagtctatg ttttagtctg
     4381 attcatgctc aaggaagcac gaatcaagca aacttaattg gccttcaaca tcaaattcct
     4441 tggttttcat ttttattgtt cttaatcaat gcgagtatgg ttgaagaatt tctgtatcga
     4501 gaaattttat ggaatttggt cagaaaatta gatatcagag ttgctttgac aagtgtttta
     4561 tttgccttag cacatcatac aggaaccatt ctagcttggt gtttgtatgt ttcacttggg
     4621 atgtttttag gtatggtgcg ctataaatct gacttatggg gcagtatggg actacatttg
     4681 gtgtggaacc tactagttta tagtttgctg cttttttaaa ataggtgacc tgatttttag
     4741 gtaacttcta aaactaactt ccagttttgg gagagagatg gaagttactt tgaaaagtta
     4801 cggaaacatt attttctatg tgacaacatt gtataattgc ttgcatttta ctggtggaga
     4861 gagtataatg agggtggata aagtacttaa tcccaaaaat ttaaatagga ggagctagct
     4921 atggcagaag aagtattaaa tcttcaatta gtatctgttc aagttgacga aacagatgaa
     4981 gttgatggaa tgcgatttag tacattcagt acaaatcgtt gcggtaactg gagtgctttt
     5041 agttgggaaa attgttaatt catttaaatt gtaaacttta gagattctct ggagttatgg
     5101 atgtcgttcc aatatgtgca cgttggaatg ttagtgctta tatggggaga atccaaagga
     5161 ttctcccttt ttatttaaat aagtctgtct agctatagat atattaagtt tgataaaatt
     5221 tcttggagat tttgttatgg attataattt caatttggag catcctttct ttttcactaa
     5281 taatgattat agtacagata ctagcataaa gtaccaagta agtctgcctt ttaattggca
     5341 cgaagtaatg aataatgatg agtgggttta tcaataccct attggaaaat ttgttgaaag
     5401 acaagggtgg aaaatacaca ttagttcaga gtataacagt tcacatgaat tgttacaaga
     5461 tgtagcaaaa atttgccatg aaatgcgaat tccatttaaa catcttagta cagaagacaa
     5521 atttatcatg cgaaacggga aattggttag tcgaggattt tctggtaaat ttattacatg
     5581 ttatccaaat caaaatgaat tagagtcggt tttgcaaagg ttagaaagtg ccttaaagca
     5641 atataatggg ccatatattt taagcgataa acgttgggat gaagcaccaa tatatctgag
     5701 gtatggtgtg tttaggccgt caagggatga tgaaaagaag gttgctattg atgaattaat
     5761 tgttggcgat gaagttgtta aagatgaacg tttaccagta tttaaaattc caaaaggtat
     5821 agtgccccct gactttttga ataaatggct tgacaagaaa gataaaaaac agggagactt
     5881 tccctttatt atagataatg caattagatt ttcaaacagt ggtgggatat ataatgctag
     5941 gctaaaagaa gatgggaaaa aaataatttt aaaagaggct agaccgtata caggtctagg
     6001 atttgatggt acttattctt cagagaaatt agcttcggag tgcaaagcac taaaaattct
     6061 aaatgaatgg agtgagacgc ctaaaatata ctggcacggt aagatctggg agcacacctt
     6121 cttaggaatt gaacatatga agggcgttcc actaaataga tgggttacca ataattttcc
     6181 tttatatgaa gttgttgata agaccaaaga ttatctattg agagtttcaa agatagtaga
     6241 aaaactcatc gatttaacga ataagtttca ttctgaaaat gtatatcatc aagatttaca
     6301 tttaggaaat atcttggtta aggatgaaga tgagattagt ataatagact gggaacaggc
     6361 tgtcttttca aatgatgaaa aagttgtaca taaagttgca gcccctggtt ttagagcatg
     6421 gcgagaaaca cttcccagtg agatagattg gtatggtatt agacaaatag ctcattattt
     6481 atacatgcca ctagtaacta catcggattt gacatacaac tatgtaagtc aaaccaggat
     6541 agaaggaaaa aaactatttg agtctttggg ttatacaaga gaacatatag attatgtaga
     6601 aagtttattg tcatatctag attctaaatg tccacagatt gagaatattt ccaggaaaaa
     6661 agttttaaaa cccatgcatg agattagaac tatcgagagt gagcaagata tacaagattt
     6721 tattataaaa ttattgagag ggtttacgct aacttatgga cagtggcgta aagaatttca
     6781 atcaagattc ttcccagttc attattatgg tctgaatttt aatcaaggaa ttgcgttttc
     6841 agatttagct atcctttgga gttatcaaca actagctaag aaagtaaaaa atttcaagtt
     6901 tgatgactat tatgagattc gaacacaggt tattaatgag gcagtaaata attttaagaa
     6961 atcgtccctt tctggtcttt ttgatggtaa aattggtaca atctggctca tttatgaatt
     7021 tggggagata gatcgggcag ttgaactttt tacaactcat tttatagaga tatttgagaa
     7081 ttcacaaaat aaaaatttat atagtgggca ggctggaatt ttactggttg gactgtattt
     7141 tcttagtaaa ggggaaattg ataataaact aggagaagaa atactaatta ggcttagaga
     7201 atatacttta aattatatag aaaatccaga aactttttgt aaagttggcg ctagtgatgt
     7261 tcagagtaat gatccttatg agaattttgg tggattacta tatggtcacg caggggtagc
     7321 ttggctcttc ggtgaagctt ataaattaac tggtgaaagt atctataaaa atggtctaga
     7381 attggctgta gataaagaat tagttgctta taaagtagat agtaataatt cattgcagta
     7441 cagccaaggt catagattac taccatatct agcaactgga agtgctggcc tgcttttact
     7501 tattaataga aataaagaaa tcttgtcaag caaatactta aaatatttaa cttctttaga
     7561 gagggcaact gatgtagttt tttgtgtatt accaggttta tttaacggat tttgtggtct
     7621 tgaagttgct aataatatat atagtgatat cgatgataac ttttcaggac aaaagaaatt
     7681 aattgaacaa ctttatagat atttgtgtgt aattgaagaa ggatttgtta ttgcgggaga
     7741 taatggttta aagataacaa cagatattgc ttcgggattt gcgggtgttg caattggatt
     7801 ggtatcaata atggataata aattgacgat tcttcctcaa atataatatt tagataccat
     7861 tattaagggg tcatacttgt gaatcagagt aatgaaatat ttttaaatac aatacaggaa
     7921 aaaacacact ataagaggtc tatctcttca tcatttcagg aattaaaaaa atggaattct
     7981 ttgatattta ggagagggcg atattggtac caatttgata attggagtat acccaatact
     8041 ggtgtaataa aggaatggta tgtcgaagat aatgactgga ttcctaaggt tagttcttcc
     8101 agtttagaca attcaaattc acttaaaatt gtctttgatg tggaaaaata tactttgcca
     8161 gatgatagta tcttacagga tgttaggatt tcatctgatg agagttatat agttttggtt
     8221 gtatcctcac tgcgtagcac taatttaatt ggaataaaaa aatatactat ggaagagtta
     8281 tttatcattg aagatatttc agtagaaagt tcgttctatt tgggtaaatt cggtgttatg
     8341 tatactcgct ccaaagagta cgggaggcca agtaagttat tctataaatc ttttgatagc
     8401 tttacagaag aggaactgtt tgaagaaaac gaatgctctt ttcgattaaa aatagtccac
     8461 attgatagca ataattgttt tgtaaagtca gtagactttc agaaaggcag gatttttcta
     8521 tacagtttcg accggacggg ttttgttaga cactcttaca cagaaacggt agccccaaca
     8581 cctagagata tcgctctatt tagtacagaa aaagcacagt actttcttgg gctctcttca
     8641 actgaagaaa agaaagatca actaattcta agggaaactt cttcgggaga cagagtttct
     8701 attactatac catatcaaga tagggctaga agagttcact gtataggacg ttatatcctt
     8761 ttagactgtt caaacgcagc gaattccgtc ttttatcttg ctacatttaa aaataatagt
     8821 ttgagggagt tgagtgttaa taagataaca tttgatgaaa agacaacact ttatgaaaat
     8881 tcattttctg atcgtgttct tctgttttta gagaggagaa ctttttacga aaaaatactt
     8941 agttttgatt taatagaaaa tacattaaaa actgaatttg aaagacccat cataaaatcg
     9001 aataatacta aatatttttc taaggtgatt tggactaaaa aagacagtta tgatgtaagc
     9061 ataccgattt ctttattttg gaaaagtgaa gatacggatg agctcccaag aagaaaaaaa
     9121 tgtattctaa gtgtctatgg ggcttatggt aagaatgata attctgattt agatgaaatt
     9181 atgttatcta taatagatgc aggttttatt tatgctatag ttcatgtaag aggtggaggc
     9241 tatttgggtg gtgaatggta tcgctcagga aaggcgttaa acaaatggaa ttctatcaga
     9301 gattttattg agggagtaaa ttatttaagg gaaaatgatg taattgacag taagcgatta
     9361 ggtttaataa cttctagtgc aggtggaata attgctggtg cggtgttgaa cgaggaaaaa
     9421 aatttattgc aaagcattct cttattttcg ccatttataa atccttatga tacacttcag
     9481 aatccaaatg atcctctttc taagaccgaa atagcagagt ggggagatat tagagaccct
     9541 gaagtaaagg cttatataaa gtcatattcg cctatgcaaa atattgaaaa ggcacgagac
     9601 tcaaatactg ttatagttaa tattttgggt gagaaagacc catatattaa taataacgaa
     9661 gtgatagagt ggtcaaagaa attaaattct attggagtta aaagtttgtt gtatttaaac
     9721 aaagcagctg gtcatggagg ttttactcca tcagatgttc tcttaatgat tgatacttta
     9781 aattatttct ttgaagaagt gggaaggaat aacttatgaa ttatttaaaa tttataaaaa
     9841 agactaaact tatattaatg gggattttaa tatttctatc ttcgtttaat ggtgtcttgc
     9901 tctcaggaat tattgtatat gcaggtagtt taaatcagac ttcctcattt tctgacgttc
     9961 taagatttgg tgctataagt attctgggtt ggtcagcaat ctatatatca aattactatt
    10021 tagaagtaac ggaagcatca ataacgaaag atataaatgt aaaaattaaa caaggatatt
    10081 ttagagaaca gtatctttct tctgaaatgg ttaaagatta ctcatctatt atttcagttt
    10141 tgtcaaatga tttgagatta atcgaagaaa actattttag acaaattttt gaaataattt
    10201 cttcaatatt gttgttcatc gtctctctaa gttttatgct ttatttaaac ttcctagttt
    10261 caataatatt tattgtatta tcagcattgc cgattatagt acctgtcttt atgaagaaga
    10321 tgttgtctaa ttcagctaat gagtactcta acagcaatgc agagtatact cacataataa
    10381 aagaaatttt taatggtttt aagacattaa aatcttattc tgttactaaa gaaataatta
    10441 gtttgtcgga taaaaagttg gataaactag aagattctac ttttaatttg aaacgatcag
    10501 aggttctttc aaaattggtt gcagtactaa tttcaggttt ttgctttcta gttcccttgg
    10561 ttgtaggatg ttattttgta atttatcata aaagcctttc ttttagtgaa ctgataggta
    10621 ttttcttagc aaacgataaa gttttagggc cgatacaatc aattgcctat tcattaaata
    10681 agataaatac aaccaaagat ttaaggaaac cgtttttaaa atacttaagt ggagagaaga
    10741 attttataga cgctgaacat gataataacg gactgtatac ttcatcaata gatgagatac
    10801 acatgaaaga tgttgtatat tctattacac cagaaaataa attaagtatt gacttctcat
    10861 ttaagtcacc atttagggta ttattaacag gaacttctgg tagtgggaaa acaacgattt
    10921 taaatttaat taatggttct ttaaagccac aaaaaggtta tgtaaatttg ttatcacatg
    10981 ggaaaaagag ttcagattca ataccaacag ttgatcagac accatatatt tttgacacta
    11041 ctattcgtga gaacgtaact ttatttcaaa atgaatattt ttcagatgat cagataattg
    11101 aggtgttaaa aaaggtaaat ctatatgaag aattagaaaa gatagatata ctaaattatc
    11161 aatgtggtga aaatggtagt aatttgtctg gaggtcaaaa acaaaaaata gctttagcta
    11221 gagctctgat tagaaataat aaagtgtact tatttgacga aatatcagct aatttagata
    11281 atgataattc aaattccata catgatattc tgttcaattt aggtatttca tttattgaag
    11341 tttcacatca ttatgactta aatgacaaga gatacactga tatatataaa ttggaaaatg
    11401 gaacactttt caaaattaag tgattggagg caagaatatg gataaagatt atatattaaa
    11461 agtgaaaggg ctgtatcatc aatttttact aggaaataat aaaacgttgc aagtgctgaa
    11521 aaatgtttct ctttctgctt cgagaggaga atttataagt attctaggaa ttagtggttc
    11581 tggaaagtca actttattaa aatgtatttc tagtttgctt gaaccaacaa gtggggaagt
    11641 aattttaaat ggaatcaacc cctataaaat cagaaatgca aaattgtcaa gtataagacg
    11701 taacgaagta tcttttatat ttcaagcata caatttaata ccttccctgc cggtaataga
    11761 aaatatagca cttcctttgc gattatcaca aaaaaaatta actattaaaa atgtagaaaa
    11821 cttactcaaa agaatgaagt ttaatgctgg cttaaacgat tttgttggaa ctctgtctgg
    11881 tggagaacaa cagaaggttg ctatagctag agcggttatt gctgatagtg atataatatt
    11941 tgctgatgag ccaactgggg ctttagacag cgtttctcgt gaagtaattt ttgaattatt
    12001 gagagagtta gtaggggcgg gtaagtgtgt aattatggta acgcacgata tagaattggc
    12061 ctcgaaaact gatcgtgcat taatattgaa agatggaaaa attttcaaag aacttcatag
    12121 acctagcggg gaagagttgt ataaaatctt agaggtacaa tcaactacgg aggaatagag
    12181 atgctcagat tagtttacta tcaattttta cataataaga aacaatggtt aggcgtttca
    12241 ccagtaattt ttgtttcgag tttagttatg ggattggctg ttaatggggt aattaatgtt
    12301 gagaataatt cgcaagtatt tgtcggactt ccagatccta aaccaatttt tatgtttccg
    12361 atagtattcg gaggagtaac attattcttt gtgctctcta acataataaa tatgttggtt
    12421 gaaattttta gagatgatta cgaacttctg gaggtgttgg gagcaagtct ccttcaacta
    12481 tcatttcttg tggggggaca gatttttatc atttcctcga ttattagttt tattgcatat
    12541 ctatgctcta tatttgttac gtcaaattat tattattttt tacaatactt tttcggggaa
    12601 aatatattac ctgatatcca atttcaaacg agtgctgttg gatgtatcat tacagtagtg
    12661 ttgatttcat ttttagcctt tctaagtggt tgcttttata cgttcaagaa gattagaaat
    12721 aggaagagtt ctaaaataag gcatgttctt tcaatagtaa aaagaatact gctattggct
    12781 ggttttagtg ttatctggtt gctttctttg caacaaattt tccaagatag cacaatttta
    12841 gcgaaggccc agataatatt caatattgta atcttagata ttgtgattat ttatcaatta
    12901 tctcctttta tacagtcatg ttttatcaaa ctactttcta taattatatt tagaaataat
    12961 tttatgttca ttgcttcgaa gtggaattta ctatatcgta agccttatat aaaatctatc
    13021 agtgctgcaa ttacaggagc tatattacta atttctagtt ttcaaatgat ttctcagaat
    13081 atactatctc aatttcaaga tgacagtgat ttagagctaa aagtggcatt tattgtctat
    13141 gtaggagcac caattttgat agtacttgca aatattattt caattgcatt tttgtcatcg
    13201 catcaagaaa ggattgagat tcagcaattt gaaattttag gaacttctaa ttaccagatg
    13261 gttaagatta aagttggtga ggctatattt ttgacatttg ttacttcatt aattgcattt
    13321 ttacttaaca ttaaaattat ggctttaata tactactctt tagaggatgt tttaatagat
    13381 gatatgaatc ttttggggtt aatacttcca aattttatag tgtctattat tttatttatt
    13441 ttaatattta ttactaaaag ttcctatttt atctttaaga atgcaaaaat tatttcttaa
    13501 aaatttgtaa gttttcgcta tataaaatag ttaaatctat tttgtatcat tgcttgcatt
    13561 ttactggtgg agagaatata atgagggtgg ataaagtact taatcccaaa aatttaaata
    13621 ggaggagcta gctatggcag aagaagtatt aaatcttcaa ttagtatctg ttcaagttga
    13681 cgaaacagat gaagttgatg gaatgcgatt tagtacattc agtacaaacc gttgcggtaa
    13741 ctggagtgct tttagttggg aaaattgtta attcatttaa attgtaaact ttagggattc
    13801 tctgaagtta tggatgtcgt tccaatatgt gtacgttgga atgttagtgc ttatatgggg
    13861 ggaacagaat cctctcttga ttgaagacaa gttagccatt aggctggttt gtctctttgt
    13921 caactgtagt gggttgatat aatagtatta gtgagtggga taaaagtttc atttagttta
    13981 ttcagtacaa atttaacggg tcaagattta ttgaactgca ccccaatagt tagacagaa
//
LOCUS       DAVBIC010000054        14013 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.054, whole genome shotgun sequence.
ACCESSION   DAVBIC010000054 DAVBIC010000000
VERSION     DAVBIC010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14013)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14013)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14013
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.054"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            complement(122..1972)
                     /locus_tag="VQ664_001754"
     CDS             complement(122..1972)
                     /locus_tag="VQ664_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HET2789869.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMVDFWGLSASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVARAVDEAKVPKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(2040..3179)
                     /locus_tag="VQ664_001755"
     CDS             complement(2040..3179)
                     /locus_tag="VQ664_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET2789870.1"
                     /translation="MSSKVSGFQDKNGKVLKIMIEWWKGKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKENIEILFINAMSTDGTTAIIQQFIKEDAEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGGLILKIDAHSKVTESFVMNNVAVIQQGEFVCGGPRP
                     TIVKGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREHGYKIRYSPSILSYQYIRPTFKKMLHQKYSNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLSLLTLLTLLKHK
                     NGFLIVMPFLLFSIHFAYGLGTIVGLIRGFKWKKEYKGTVIYLEK"
     gene            3237..4403
                     /locus_tag="VQ664_001756"
     CDS             3237..4403
                     /locus_tag="VQ664_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HET2789871.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTRLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFY
                     TAMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVVGISMLFFPINNFIYWLAIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPAVAALLLIDILMTVALFTVDRADKIL"
     gene            4542..4868
                     /locus_tag="VQ664_001757"
     CDS             4542..4868
                     /locus_tag="VQ664_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HET2789872.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWTLYTDTINGIIEGS
                     IRHDKN"
     gene            4855..5448
                     /locus_tag="VQ664_001758"
     CDS             4855..5448
                     /locus_tag="VQ664_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HET2789873.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEVAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTVLAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYVARFFGLLIVRLVQFVLKKGKRGNQHA"
     gene            5441..6352
                     /locus_tag="VQ664_001759"
     CDS             5441..6352
                     /locus_tag="VQ664_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HET2789874.1"
                     /translation="MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPVY
                     DSRTEKLTFGKEVENLEITLHQHTLTITDSFDDQIHISYHPSLSAHHDLITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILRLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTENHFHAEN
                     IQVHGKVELTAKDYLRIILDQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            6415..7479
                     /locus_tag="VQ664_001760"
     CDS             6415..7479
                     /locus_tag="VQ664_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789875.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEEQAQEVADKAEETIADLDTPIGK
                     NTQVEEEVSQAEVELESQQEEKIETPEGGEARTEIEEKKASNSTEEEPDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLESPYIPDQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKLETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIISILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(7551..8411)
                     /locus_tag="VQ664_001761"
     CDS             complement(7551..8411)
                     /locus_tag="VQ664_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 domain-containing protein"
                     /protein_id="HET2789876.1"
                     /translation="MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHIYDVVYLRQ
                     PLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTETDWQIIKSFLDALLAYT
                     GTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLA
                     QFEARVRAVQETDAYFARVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPAAYIEQLV
                     DKEVQWEIDLVQITGDGSKPEDYEAIARLDYAKFLEVLPPSFYHQLDANQIEVQPILD
                     KDFKTLAQEK"
     gene            complement(8533..9519)
                     /locus_tag="VQ664_001762"
     CDS             complement(8533..9519)
                     /locus_tag="VQ664_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HET2789877.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEELWFKIDEENEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            complement(9791..11266)
                     /locus_tag="VQ664_001763"
     CDS             complement(9791..11266)
                     /locus_tag="VQ664_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3502 domain-containing protein"
                     /protein_id="HET2789878.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            complement(11370..12293)
                     /locus_tag="VQ664_001764"
     CDS             complement(11370..12293)
                     /locus_tag="VQ664_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET2789879.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            complement(12307..13236)
                     /locus_tag="VQ664_001765"
     CDS             complement(12307..13236)
                     /locus_tag="VQ664_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2789880.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            complement(13555..13905)
                     /locus_tag="VQ664_001766"
     CDS             complement(13555..13905)
                     /locus_tag="VQ664_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789881.1"
                     /translation="MTGVSNPTTDSARLVLAEAKKAFADDSLTEQGLRDILQTVKDAI
                     ASLESIKESQSATKDGGQTAGKETADKDVLENSQEELQKAVLFLADEKGSEHTEAELI
                     DNLKEVIAKLKANA"
BASE COUNT         4190 a         3027 c         2582 g         4214 t
ORIGIN      
        1 aaccatatac ggcaaggcga cgttgacgtg atttgaagag attttcgaag agtataagtc
       61 tctacataat aaaacgcata ttaccaaggt tatttaactt gataatatgc gtttttcttt
      121 tttattcaat gtgggttgtt tgattagcaa aggcgataat agcttgcttc aactcatctc
      181 cactgagagt gcggaactct ccaatctttt gattgatgga ttctaaaggc atgacattaa
      241 ccttaccaac gaaaatctta tccataactt gattatcaac gagttcggtt gataccaaga
      301 gttcttcgta gagtttttca cctgggcgga ttccaacttc aacgattgga atttcacttt
      361 cagtgtggcc acttagaagc accatcttct tggccaagtc ataaatcttg actggtttgc
      421 ccatatcaag gataaagact tccccatctt tggcataagc accagcatgg ataaccagac
      481 ggctagcttc tggaatggtc ataaagtaac gggtcatgcg gaagtctgtc accgttacag
      541 gcccaccttc agcaatctga cgttcaaaga ctggaatgac actaccacgg ctaccaagaa
      601 cattcccaaa acgaactgca cagtaggttg attggctacg ttggttaaag ccagtgacaa
      661 tcaactccgc cacgcgcttg gttgctccca taacatttgg tggattgact gccttatctg
      721 tcgaaatcat aaccatctta ggcaccttgg cttcatcaac ggctctagca acattgtaag
      781 ttccacggat attgtttttg aaggcttctt ttggattgcg ctccatcata ggaacatgct
      841 tgtgggctgc cgcatgataa acaatagcag gtttgtactg ctcaaagact tgcaacaaac
      901 gatcatagtc ttgaatgtcc gcaatcacag gtacataatc aatcccttgg aacttacgaa
      961 tcaattcatg ataaacaagg tagattgagt tttccccatg accgagcaag acaatgcgtt
     1021 caggattgaa gcgactaact tgacgacaga tttcagaacc gattgaacct ccagctcctg
     1081 tgactaagat ggtcttacct gtcagttctg cacccagacg cgattcgtca agacggattt
     1141 cctgacgacc caaaaggtcc gtaatatcaa ttttttggaa gccagtacct gcttggtgaa
     1201 ggccctgaac aacagtttca accttaggca tcttgtaaca tttgacaccc agcttattac
     1261 acatctgcaa gatacgctca tattctgacg gatccagcga cggaatcgca acgatgacac
     1321 gctcgatttg atggcgtttg gctaattcag gcagattgtc ataagagccc aaaacaggaa
     1381 taccaccaag tttttgaccc tttttcttag aatccttatc caaaataccg accagttcta
     1441 attcactggt tggatgttgg taactatcca taaagagagc cccaccatca ccggcaccaa
     1501 tcaagaaggt ccgacggtgt tctccatcac cactaccttt tttgcgtctg gagtagatta
     1561 actgccaagt aatccgtggc aataaaatca agaaggtact caacaagata aagagaatga
     1621 taaaacggat ggagaagagt ggcaagaagg cataacagat actatatgac aagacactgc
     1681 tagcagtcac accaaaaaag attttcatga aatccgtaat cttgctgtaa cgactaatac
     1741 tcgcgctcaa gccccaaaaa tcaaccatca attgatagaa caggaaggcc aaactcgtat
     1801 agataatgta gtcaacaggt gctggattaa tcagcccata aaataaaata taagatacaa
     1861 tgatggaaac caccatactg aaaatatcaa atattcccca gaaaacctgc ttttgttgtt
     1921 tatttaaaat ttccaccaga tcaatcacat aatctgtgag ttttttattc atagaaattt
     1981 actcctcctt aaaatagttc tactatattg ttattatagc acattttaat ttatttggct
     2041 tatttttcca aataaattac tgttcccttg tactccttct tccatttaaa tcctctaatt
     2101 aaacctacaa tcgtcccaag gccataagca aagtgaatgg aaaataaaag aaagggcatc
     2161 acaattagaa atccattttt atgttttaat aaagtcagca aagtgagtaa tgacagtaat
     2221 gataaaagta gaaaataggc acctaatagt aaagttatga atacgaatgt gatcggtaac
     2281 aatgctagac taaacacaag actcaaaaca aataaacaag gaacataatg aaataatgat
     2341 aaacacttaa actgaacatg acttgtcaag ccaatccaca aaccatttga atacttttga
     2401 tgcagcattt tcttgaatgt tggtcgaata tactgataag atagaatact tgggctatag
     2461 cggattttat aaccatgttc tcgaattcta taatgaatat cattatcttc agttcggcca
     2521 agttgctcat ttactaaacc aaccttctgg aaaacctctc gtttatacat cccatgaaaa
     2581 atagaagaaa catatctatc ctcggaacta tttcgataat tggcaatgct actgccaaac
     2641 atattttcct caacaagatg caaggtctct gcccattttc cttttccttt gacaatcgtc
     2701 ggtctaggcc ctccacagac aaattcacct tgttgaataa cagccacatt gttcattaca
     2761 aaactctcag taacttttga atgagcatca atttttaaaa taaggccccc tacagaatgc
     2821 ttaactccca ggttaaaacc actagcttga tttttcttag gattgttata caatctaatt
     2881 gagttaaact ctgcatcttc ttttataaat tgctgaatga tagctgtggt cccatctgtg
     2941 gacatagcat ttataaatag aatttcaata ttctctttag gataggtttg attttttaag
     3001 tcttcaatta gaccaggcag atatttttct tcattgtatg cactgattac aatggatacg
     3061 agaagacttt caacattttg agtcactact actctcctga attttccctt ccaccattct
     3121 atcataattt tcaagacttt tccattttta tcttgaaagc cagaaacctt acttgacatt
     3181 atagtgaaaa agccttaaaa taagctgtta ttaaaatcag ctagaagaga tattatatga
     3241 aaaagcaatc actctttttt gttccaggta ttatcctgat tggtgtttcc ttgcgaactc
     3301 cttttactgt tttacccatt attttgggaa atatttcgca aggtctggag gtagaagtta
     3361 gttcgcttgg tgtcttgacc agcctgcctc tccttatgtt taccctcttt tcaccatttt
     3421 ctacccgact ggctcagaaa atcggcttgg agcatctctt cacctacagc ctcttcttct
     3481 tgaccatcgg ctcacttatt cgactaatca atctgcccct gctctatcta ggaaccttga
     3541 tggttggggc aagtgtcgca gtcatcaatg tcctgcttcc tagtcttatc caagccaatc
     3601 aaccaaagaa aattggtttt ctgaccacct tatatgtaac gtctatgggg attgcaacgg
     3661 ctctggcttc ctatctagct gtgcccatta cacaagccag ttcttggaaa ggacttatcc
     3721 tcctcctcac gttactctgt ctagcaactt ttttggtctg gctcccaaat caccgctata
     3781 atcatagact agctccacaa accaaacaaa aaagtcaaat aaaggtcatg cgtaataaac
     3841 aggtttgggc aattattatc ttttcaggtt ttcaatcctt gatcttttac accgccatga
     3901 cctggttacc taccatgtct atccatgcag gtctatccag tcacgaagct ggcttgctga
     3961 cttctatctt atctctgatt agcattcctt tttcaatgac catcccaagc ctgacaacca
     4021 gtttatctac tcgcaaccgt cagctcatgc tcactctggt ttcactagct ggtgtggtcg
     4081 gcatttccat gctctttttc ccaatcaata atttcattta ctggcttgcc atccatctcc
     4141 tcatcggaac cgcaaccagc gccctcttcc cttatctcat ggtcaacttt tcactcaaga
     4201 ccagcgcccc tgaaaagaca gcccaattgt ccggcctatc tcaaacagga ggctatatcc
     4261 tagcagcctt tgggccaacc ctctttggtt acagttttga cctattccac tcttgggtac
     4321 cagctgtagc tgccctcttg ctcatcgata tcctgatgac tgtggccctc tttacagtgg
     4381 acagagcgga taagatcctt taaacttcta gttttagcta gaagtttttt atatataaaa
     4441 attttacaca tttctcttga cagggctttc ttttagatgt acaatgtatg tgtagaaaaa
     4501 ttatatataa aaatcttaca cattagaaaa ggaggtttcc catgtacttt ccaacatcct
     4561 ctgccttgat tgaatttctc atcttggctg tactggagca gggtgattct tatggttatg
     4621 agattagcca aaccattaag ctgatcgcta atatcaaaga atccacactc tatcccattc
     4681 tcaaaaaatt ggaaggcaat agctttctga caacctattc tagagagttc caaggtcgca
     4741 tgcgcaaata ctactccttg acaaacggtg gtatagagca gctcttgacc ctaaaagatg
     4801 aatggacact ctatacagac accatcaatg gcatcataga agggagtatc cgccatgaca
     4861 agaactgaat acctgactca gctagaactc tatctcaaga aactacctga agctgaccgt
     4921 atcgaagcca tggactattt cagagagctc tttgacgatg ctggagtcga aggagaagaa
     4981 gaactcatcg ctagtttggg aactcccaaa gaagtggccc acgaagttct atccaatctt
     5041 ctcgataaaa aaatcaatga agcacccgct caaaaaaata accgacaaat tttacatatc
     5101 gccttgttag ccctccttgc agcacctatc ggcattcctc tgggaatcgc catcctcgtg
     5161 accctgttcg caatccttgt agccgctttg actgtcattc tggctttctt tgcagtttcc
     5221 atactgggta tcatcggcgg attcctattt ttagttgaaa gtttcactgt cctcgcccaa
     5281 gccaaatcag cctttatctt gatttttggt tctggtttac tggctatcgg tgcttcttcg
     5341 ctagttttac ttggcatttc ctatgtagct cgcttcttcg gtctactcat tgttcgtctg
     5401 gtacaatttg ttcttaaaaa aggaaagaga ggtaatcagc atgcgtaaat ggacaaaagg
     5461 atttctcatc tttggtgtgg tgactaccgt tatcggcttt atcctgcttt ttgtaggtat
     5521 ccaatctgac gggattaaga gcctactttc catgtccaaa gaacctgtct atgatagccg
     5581 tacggaaaag ctaacctttg gcaaggaagt cgaaaaccta gaaattactc tccaccaaca
     5641 cacgctcacc atcacagact ctttcgatga tcaaatccac atttcttacc atccatctct
     5701 ttctgctcac catgatctta tcaccaatca gaacgataga actctgagtc tcactgataa
     5761 gaaactgtct gaaactccgt ttctctcttc tggaattggt gggattcttc atatcgcaag
     5821 tagctactct agtcgttttg aagaagttat tctccgacta ccaaaaggga gaactctaaa
     5881 agggatcaac atctcagcca atcgcggaca aaccaccatc ataaatgcta gccttgaaaa
     5941 tgcgaccctc aatacaaaca gctatatcct ccgaattgaa ggaagtcgta tcaaaaacag
     6001 taaactcaca acgcccaata tcgttaatat ctttgataca gttcttacag atagtcagct
     6061 agagtcaaca gagaatcact tccacgctga aaatatccaa gtccatggta aggttgaact
     6121 gactgccaaa gattatctca gaatcatcct agaccagaaa gaaagccaac gaattaactg
     6181 ggacatctca agcaactatg gttctatctt ccaattcaca agagaaaagc ctgaatcaag
     6241 aggtacggaa ttaagcaacc cttacaaaac tgaaaaaacc gatgtcaagg atcaactcat
     6301 tgcgagatct gatgataata ttgatctaat atccacacca agcagacgtt gacaaaaacg
     6361 cttacatctg ctactatgga agcatattta tctaactaaa aaggaggttc taccatgaaa
     6421 caagaatggt ttgaaagtaa tgattttgta aaaacaacaa gcaagaacaa gcctgaagag
     6481 caagctcaag aggttgcaga caaggctgaa gaaacgatag ccgatctcga tacaccaatt
     6541 ggaaaaaata ctcaagtaga ggaggaagtc tctcaagctg aagtcgaact ggaaagccag
     6601 caagaagaga aaattgaaac tcctgaaggc ggtgaagcga gaacagaaat agaagaaaag
     6661 aaggcatcta attctactga agaagagcca gacctttcta aagaaacaga aaaagtcact
     6721 atagctgaag agagccaaga agctcttcct cagcaaaaag caaccacgaa agagccactt
     6781 cttatcagta aatctttaga aagtccttat atccccgacc aagctccaaa atctagggat
     6841 aaatggaaag agcaagtgct tgatttttgg tcttggctag tggaagcgat caaatctcct
     6901 acaagtaagt tggaaacaag tatcacacac agttacacag cctttctctt gctcattctg
     6961 ttttctgcat cttccttttt ctttagtatc tatcacatca aacatgctta ctatggacat
     7021 atagcaagca ttaacagtcg cttccctgag cagctagctc ctttaactct tttttctatc
     7081 atctctatcc tagtagcgac aacactcttc ttcttttcat tcctcttggg tagtttcgtt
     7141 gtgagacgat ttatccacca ggaaaaggac tggacgctag acaaggttct ccaacaatat
     7201 agtcaactct tggcaattcc aatcttcctc actgctattg ctagtttctt tgctttcttt
     7261 gatagcctac gatttacggc cctcttgtgt gtgattagca ttggaatcat tctgcttgcc
     7321 agtctccata tcattacaag accaagtcaa gcaagtgaaa ccgactcctt ctatcaatta
     7381 ttcttgtctg tccttgtgaa cggagttatt atcctcctct tctttgtagc tgaagtggca
     7441 ctgattggag attatcttcg tatcttggcc tttctttaaa attcaatcct gtcatccttg
     7501 gcaggatttt ttctatgtca aaaaagcaag tcgattgacc tgcttctgct ttacttttct
     7561 tgtgctaatg ttttaaaatc tttgtctaat atgggttgca cttctatttg attggcgtct
     7621 agttggtggt aaaaagatgg gggtaatacc tctaagaatt ttgcatagtc caagcgagca
     7681 atggcttcat agtcttctgg tttagagcca tctcctgtga tttgaaccaa gtcaatctcc
     7741 cactgcactt ccttatccac caattgctca atataggctg caggaacaaa cggttctctc
     7801 ggtaaaactg tcttgactcc ttgagctaga tggtaaacgc catgcacttt tccttctcca
     7861 tcctgataga aggaaactct cgcaaagtag gcatctgtct cttgaaccgc acgcacacgc
     7921 gcttcaaact gagccaaacc atctgcctct aaaaagcttt tcaagttctc acgactaaag
     7981 aaaataggat taaaaattcc ttggcaaatc gtaaaacgag ctacagggtc tgctagatag
     8041 gcttgaatac ttgcttggaa ataagcttca aaatcaaaac catctagccc ttcaatatca
     8101 gtccctgtat aagcaagcaa agcatctaaa aatgacttga taatctgcca gtctgtctct
     8161 gttagtaggt caggaagatc gacacggtaa gccttttgac catcagcata actgacctta
     8221 aaaagaaatt gtgattgccc cactatcgca cactcaatat actcgagacg attaagaggc
     8281 tgacggagat agactacatc atagatatgt gactccaaac cgtctagcaa tgccaagatc
     8341 gacttggcat tcaaaatctc ttgttctcct aaaatgctct gtttatttgg aataaaaaat
     8401 gttttcgcca taactggact cctttgaaat cgcttacata cagtatacct tatttttctg
     8461 aaagatacag aaacaaactt tagatttttg agtacaaagc atagaaaaac agcccctgag
     8521 gactgtttga tcttatacag tagctgcttg atccaagctt tcaccgatag cggctaggcg
     8581 ctcgatcact tcagcttgtg tcaattcatt ttttgaaaca tagcggttac gtgggtgaac
     8641 acggcactcg tgtgagcatc cacgaaggta cttgtcttca ttttcttctg atgtcaagat
     8701 acgacggtta cagaagggat ttccacagtt gacataacgt tcacatggtg ttccatcaaa
     8761 ccagtctttc cctacgatgg ttgggttgac atggttgaca tcaacggcga tacgctcgtc
     8821 aaatacgtac atttttccat cccaaagctc accttgaact tctgggtctt taccgtaagt
     8881 tgcgattcct ccgtgcaatt ggccgacatc tttgtagcct tcacggacca tccagcctga
     8941 gaatttctca cagcgaacgc cacctgtaca gtaaaccacg acacgcttgt ccatgaattt
     9001 ttccttgtta tcacggaccc attgtggtaa ctcacggaag ttgcgaatat ctgggcgaat
     9061 agctccacgg aaatgtccta ggtcgtactc ataatcgtta cgtgtgtcaa ggacaacggt
     9121 atctttatca agaagcgctt ctttgaactc ttttggagac aagtaagcac ctgttgtttc
     9181 aagtgggttg atgtcattgt caaagtcgtt gtcttccaaa ccaaggtgga caatttcttt
     9241 cttgtagcga acaaacatct tcttgaaggc ttgttcattt tcttcgtcaa tcttgaacca
     9301 gagttcttcc attcctggaa ggctgtgaac gtagtccatg tatttttgag ttgtttcata
     9361 gtcacctgaa actgttccgt taattccctc gtcagcgact aggatacggc ctttaagacc
     9421 gattgattta cagaaagcca agtggtctgc agcaaattgc tctgcatttt caattggagt
     9481 ataaaggtag taaagtaaga cacgaatatc ttttgccata agatttgttc tcttttctat
     9541 tcttaaattt tctaaatttt ttatttatcc atactagtat acctgcttga gaaaacgaat
     9601 gcaatttatt tgactggaaa ttgtagagga ttctcgaaat ttcctgaatg gttaaaataa
     9661 ggacaagaga aaacatggat atctatatcc ttgtgccaaa aaaaccactg ccctccccag
     9721 accaacctga ggaaagcagt gattcttatt ttaggagtta ggaatgaata cacgaaatca
     9781 atttagctga ttattttttg tttttcaaga attcatcgta ttgtttttgc atttcgttca
     9841 atactttttc gtaggcacct tcagatttca atttttccat caattctgga atcgctttat
     9901 ctgggtctac agtaccagtg ttgatagctg tatcaaattg ttgcattgtg ttagcaatag
     9961 ctgagatttc agatttcaca ttgtcagtat tgaagataaa tccaagcgct ggagattctt
    10021 tagcttctgc caattctttc ttagaatttt cgatttgttg gtctgtaacg ttttcgttga
    10081 tgtaaaggat ccagttgtta ccagtgttcc atccacccat gtgagtgttt cctttgtagc
    10141 catcaagaac gcgaacacgg ttttctttac cttcaatttt ttcccagttc ttgccttctg
    10201 gaccgtaaac aagaccgttc aaaagttctg ggttcgtatt caagaggttc aagatttcca
    10261 ttgatttttc tttgttctta gagttgtttg agatgacaaa gttagcaact tgtgttgttt
    10321 ggtttttctt gatgaagtta gtgattggtt tgatttggat atctttgttg gcaacacgtg
    10381 aaagcaagct gttaccgtag tcagctggtc ctactgtttc ttcacgaacg aaccaagtat
    10441 cttgttgaag gtcaaatgaa gtatcgcttg ttgcgacgtc ttttggaatg tagccagctt
    10501 catagaattt gtgaagagtc ttcaagtgtt ctttgaaacg aggcacttcg taacggttta
    10561 caactttagt agtatcgcct tcaaggtcaa taacgaatgg aagcccgttt gctactgggt
    10621 agtcaaaatt atcagatggg atgaaaactt taccaatagc aaatggtact acgtctggag
    10681 ctttttcttt gatttgtttc aagactggct caagagtttc gtaagaagta acacctgaaa
    10741 tatcgatacc atatttggca aggagagttc cgttgaaggc aaagttttga gatgatgcta
    10801 cgttggctgc aactggtaca gcataaatct taccatttac agtattaccc ttgatataag
    10861 ctggatcaag tgccttgtaa aggtctttac cttctttttt gtacaattct gtcaagtcag
    10921 cataagcacc tttttgagca tttacaatat agttatctgc aaaggcgata tcatagtttt
    10981 caccagatga tgtgataact gacattttct taccatagtc accccagcca aggtattgga
    11041 tatccaattt ggcaccaact ttttcttcga tgattttgtt ggcatttgct aacaattcat
    11101 ccaagttatc tggtttgtca ccgatttggt acattttgat aacaggtttg tcacctgaat
    11161 cagcagcttt tttgctgtta cctgtcaaat ttccacaagc agcaagacct gcagccagag
    11221 cgactacact agcagatgca aaagcatatt ttttccagtt tttcatgata aaaactcctt
    11281 tttttatttt taaacttata aacaatgtaa tgatcttaac ttcacacaag ggaagttggg
    11341 aactgagaaa tgttcttttt caataagcac tattctttca caccaccgat agtcaaacct
    11401 tttacaaagt agcgttggaa gaatggatac aaaatcgcga ttggaagggt tgctaccaca
    11461 accatggcca tacgacctgt ttctttcggt agagcaactc ccagttgacc agtcaagccg
    11521 accgctttgg caatgtagtc catattttgt tggatttgca tgagcaaata ttgcaatgga
    11581 tacaagttat cactcttgat gtaaagaagg gcgttgaacc agtcattcca gaaaccaaga
    11641 gctgtcaaaa gcgtgatggt tgcgatacct ggtagtgaca atggcaaaca gatttggaag
    11701 aaaatccgag cctcactggc accatcgata cgagccgatt cgagaatggc ttctggaatg
    11761 gtcttcttga aaaaagaacg catcaagatg atattgaatg gtgagagaag cattggaaca
    11821 atcaaggccc aaacagtgtc accaagctga agtacacggg tcaccatgat ataacctggt
    11881 accaaaccag cgttgaacaa catactgaga aggacgaaga tggtaaaaaa tctgcgatac
    11941 ttaaaggttg tccgtgaaat agcgtaggca taggttgttg tgataaagac atttgtcaat
    12001 gtcccaacta cggttacaaa gacagagatg aagagggctt gtaggatttt atccttaaac
    12061 tgtgccaaaa actcaaaacc gtctaagcca aattgggatg ggaagaagct atagccgtat
    12121 tggaggaggc ttttctcgtc tgtcactgaa ataatgataa cgaatacaaa aggtaggata
    12181 caagagaggg caatcaaacc cgaaatgata ctgaagaaga tatctgcttt cttactgaag
    12241 gagtgaatgc cgacattatc aattttttct tttttaattt tcttttttgc catattctcc
    12301 tcctttctag aacaaagctg agtttggatc gactcgtctt gcaagcaagt ttgataggat
    12361 aaccagaatc aaaccaacaa cggattggta aagaccggct gctgcagcca taccgatatc
    12421 tgctgtctga gtcaaaccat taaagacata tacgtccaaa acgttggtta cattgtaaag
    12481 ctgaccagca ttgtgtggga tttgatagaa gagaccgaag tctgcgcgga agatatttcc
    12541 gactgcaagg atggtcaata cagttacaag cggagtcaac tgaggaatgg ttacgttgcg
    12601 aatacgttgc cacttgctag ctccgtccac tgtcgctgct tcgtagtagg ttggatcaat
    12661 tcccatgatc gtcgcatagt acatgacact gctatatcca aagcctttcc aaatacctag
    12721 gaaaagtagg agatagggcc agatgcccag gtcagcgtag aaattgactt ctttgagacc
    12781 aagactttcc aatagatgat tgaacacccc tttatcaata tttaggaagg catctgtaaa
    12841 gaaactgatg ataacccaag acaagaagta agggaacaac atagaagttt gaaaaatctt
    12901 caccattctc ttagaacgga gctcgctgag gataatggca atccctacag atacaactaa
    12961 acctagaaag ataaagccaa gattgtagag gacagtattt cgtgtgataa taaaggcgtc
    13021 tcttgaacta aataagaatc tgaaattatc gagtccgacc catttactat ttatgatact
    13081 atctatgaaa ccattactgg tcatgtggta gtctttgaag gcaaccacgt tcccaaatac
    13141 tggaatgtaa aagaatagaa tcaaccagag tgcccctggc aaaaccatca agagaaagat
    13201 ccagttgtct ctcaatgttt ttgaaaactt tttcataatt tcctcccttt ttattttgat
    13261 atccatctaa aaattctttt ttagactttt gataacgatt acattattag tatactccta
    13321 tttgcaggtt aggttaaact cctaattata gaaaaaactc cacaaattat gtagcagatt
    13381 taaaacttta tcaccactat caaacaaatg tcctaaatca attgtttatt ttatctctat
    13441 tagcccagtg atggcgtcac tctgttataa gcatccaaca acggggtata ctgaaaaatc
    13501 tccagactag ggaactcagc gatagttcct aatctggaga tttttaatat gttattaggc
    13561 gtttgctttc aacttagcaa taacctcttt aagattatca atcaactctg cttcagtatg
    13621 ctcagagcct ttttcatctg ccaagaacaa aactgctttt tgaagttctt cttgagagtt
    13681 ttcaaggaca tccttatctg ctgtttcttt gcccgctgtt tgtcctccat ccttagttgc
    13741 tgactggctt tccttaatgg actctaggga agcaatggca tctttgactg tttgcaagat
    13801 atcacgtaaa ccttgctctg tcaaactatc atctgcaaaa gctttcttag cctctgccaa
    13861 aaccagacgt gctgaatctg tggtaggatt cgatacacct gtcaatgatc tcaaaagatt
    13921 ttctaaagtt tgagtctgct tactaatact agactaaaat caaaaagcat tatataacag
    13981 tgatatgaaa tcaactaaag aagaaatcca aac
//
LOCUS       DAVBIC010000055        13493 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.055, whole genome shotgun sequence.
ACCESSION   DAVBIC010000055 DAVBIC010000000
VERSION     DAVBIC010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13493)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13493)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13493
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.055"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            complement(<1..1349)
                     /locus_tag="VQ664_001767"
     CDS             complement(<1..1349)
                     /locus_tag="VQ664_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec-dependent serine-rich glycoprotein
                     adhesin"
                     /protein_id="HET2789882.1"
                     /translation="MFKVMRGGVDTTQVMTETVEDKVSHSITGLDILKGIVAAGTVIS
                     GTVATQTKVFTNESAVLEKTVEKTDALATNDTVVLGTISTSNSASSTSLSASESASTS
                     ASESASTSASTSASTSASESASTSASTSISASSTVVGSQTAAATEATAKKVEEDRKKP
                     ASDYAASVTNVNLQSYAKRRKRSVDSIEQLLASIKAAVFSGNTIVNGAPAINASLNIA
                     KSETKVYTGTGLDSVYHVPIYYKLTVTNDGSKLTFTYTVTYVDPTTRALGNLSKMGHG
                     YSIYNTGTSIQTMLTLGSDLGTPSDVKNYITDKDGVLVRSYNTSTMTTWGSGYTWGNG
                     AQMNGFFAKQGYGLTSSWTVPITGTDTSFTFTPYAAKTDNIRTNYFKGRGKVVESSTT
                     SQSLSQSKSLSVSASQSASASASTSASESASTSASASASTSASASASTSASASASTSA
                     "
     gene            complement(1347..1460)
                     /locus_tag="VQ664_001768"
                     /pseudo
     CDS             complement(1347..1460)
                     /locus_tag="VQ664_001768"
                     /inference="COORDINATES: protein motif:HMM:TIGR03715.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="KxYKxGKxW signal peptide domain-containing
                     protein"
     gene            complement(1698..2159)
                     /locus_tag="VQ664_001769"
     CDS             complement(1698..2159)
                     /locus_tag="VQ664_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000514209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2789883.1"
                     /translation="MGKERRKQGNLERKKRVVKKRKIPLEELKAFVEAHPDAFLREIA
                     ARFDCALPSVWAVLKQIKVILKKTTSFREQKPEKVSEFLDILDNLKDLPVLYIDETGI
                     NRYLYRPYAGAPRGEKVYDKISGRRFERTNEVEQKLNGSFLIRYIDSQIRE"
     gene            complement(2126..2269)
                     /locus_tag="VQ664_001770"
     CDS             complement(2126..2269)
                     /locus_tag="VQ664_001770"
                     /inference="COORDINATES: protein motif:HMM:NF013842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET2789884.1"
                     /translation="MAYSTDFKQGALDSIKEGHSHVEAAKFFGVGVRTLFTWEKKDVN
                     KGT"
     gene            2538..2918
                     /locus_tag="VQ664_001771"
     CDS             2538..2918
                     /locus_tag="VQ664_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HET2789885.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKTLASLQKTVEESLEAGLDFLI"
     gene            3017..3238
                     /locus_tag="VQ664_001772"
     CDS             3017..3238
                     /locus_tag="VQ664_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HET2789886.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            3255..3569
                     /gene="trxA"
                     /locus_tag="VQ664_001773"
     CDS             3255..3569
                     /gene="trxA"
                     /locus_tag="VQ664_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HET2789887.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
     gene            3876..4409
                     /gene="queF"
                     /locus_tag="VQ664_001774"
     CDS             3876..4409
                     /gene="queF"
                     /locus_tag="VQ664_001774"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
                     /protein_id="HET2789888.1"
                     /translation="MKHQSALVVFSGGQDSTTCLFWTMQHYETVEAVTFAYGQHHHLE
                     IQITREIAKEQGIRHHILDMSLLGQITAQPDFATIHISYIPDKLCVESKSLKLYLFSY
                     RNHGDFHENCINTIGKDLVNLLDPRYLEVWGKFTPRGGISIDPYYNYGKQGTKYEGLA
                     EQRLFQHDLYPEKIDNR"
     gene            complement(4663..5331)
                     /locus_tag="VQ664_001775"
     CDS             complement(4663..5331)
                     /locus_tag="VQ664_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin"
                     /protein_id="HET2789889.1"
                     /translation="MKKFVAELIGTFMLVFVGTGAVVFGNGLDGLGHLGIAFAFGLAI
                     VVAAYSIGTVSGAHLNPAVSIAMFVNKRLSSSELVNYILGQVVGAFIASGAVFFLLSN
                     SGMSTASLGENALANGVTVFGGFLFEVIATFLFVLVIMTVTSESKGNGAIAGLVIGLS
                     LMAMILVGLKITGLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFL
                     GTEE"
     gene            complement(5442..5996)
                     /locus_tag="VQ664_001776"
     CDS             complement(5442..5996)
                     /locus_tag="VQ664_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
                     /protein_id="HET2789890.1"
                     /translation="MYQDLLRKIAEEKPNYNQEEIQWLFDHLGNPSPEIRNVLLNQGL
                     HYLSKEKDTRGFSSQYGWVHAFAHGADLLTEVVCHPGFPKNRVHEVFEILGQLFKRMS
                     IRFTDDEDWRLARVIYEPILQGKLAQEQVASWIKTVDFPIEEREDFYKFSNFRSCLVE
                     VYVQLDQRNSLQDELKEAIQSFQY"
     gene            complement(6242..8038)
                     /gene="pepF"
                     /locus_tag="VQ664_001777"
     CDS             complement(6242..8038)
                     /gene="pepF"
                     /locus_tag="VQ664_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HET2789891.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYGFMPQTTDYSNDEFANIAQAGMEFETD
                     ASVALTFFDDALVAADEEVLDRLGKLPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDATLTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKHSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIISYSAELGE"
     gene            complement(8049..8792)
                     /locus_tag="VQ664_001778"
     CDS             complement(8049..8792)
                     /locus_tag="VQ664_001778"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HET2789892.1"
                     /translation="MQQYFVKGSAVSPVTIEDRETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFITQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNVVPSIHLFENKADFLAQLDQ
                     FDRILVAYEEAAKEGEAAALIKAVTGLEKGAKLLFIFGPEGGLSPAEIENFEAKGAVL
                     AGLGPRILRAETAPLYALSALSVLVELEK"
     gene            complement(8794..9744)
                     /locus_tag="VQ664_001779"
     CDS             complement(8794..9744)
                     /locus_tag="VQ664_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000451122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HET2789893.1"
                     /translation="METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYMGNVD
                     RFGEIFPEVEQQEEIVVTAYYPDTVDMTVVEADLQARLAELTDFMDLGELKIGTTALA
                     EEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKMS
                     LFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNTG
                     MENIHVAAGDLLKGVEIEADVIVANILADILIHLTEDAYRLVKDEGYLIMSGIIKDKW
                     DMVRQSAESAGFFLETHMIQGEWNACVFKKTKDISGVIGG"
     gene            complement(9882..10310)
                     /locus_tag="VQ664_001780"
     CDS             complement(9882..10310)
                     /locus_tag="VQ664_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET2789894.1"
                     /translation="MELEISDFQGCKIALFCGDKLLTILRDDKDDIPCPNMWELPGGG
                     REGDESPFECARREVYEELGIHLDEDCLLWSKIYPSVIFKGKKSVFMVGQLRQEQFDN
                     IIFGDEGQGYQLMNVEEFLSSSQVVPQLQERLKDYLKVSD"
     gene            complement(10291..11379)
                     /locus_tag="VQ664_001781"
     CDS             complement(10291..11379)
                     /locus_tag="VQ664_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HET2789895.1"
                     /translation="MKKIGTYLVYVLAVVFIMLAFACGTIAFAELGYSAVLAFTFGYA
                     FALLSMYLIFILHELGHAFCGYLTGYRLVAFGLGHFILTKKSGRFHLSRTAILKNVGA
                     QYIGLKEDESDQRIILMLSGGLMVHLGLILLAIVFGFLTRSWYFAGTWIFLNLSFFLN
                     NILPVDITDGAKIWELLQHPENTKYAYLVLRHSAQTLLAPQEYDLKDFVQAVPEDARG
                     SFADGVLGMQGEVSILEGKEEVAKQQFQALLERTTTPMMQTVAQLSLLHIALLEGDFE
                     QAEQYASIRQVKSFLSLKLSNLQVIQAWYQLKVKKDVDRTRKALKIARQKMDSSRMLR
                     DEKRYYENLLAELEKEMLEGTEDGTRNF"
     gene            complement(11398..11868)
                     /locus_tag="VQ664_001782"
     CDS             complement(11398..11868)
                     /locus_tag="VQ664_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HET2789896.1"
                     /translation="MATYGFLDVLEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVSSDDILFEEAVLFYNPAKSTVNEEDYLTVIPYLPKKGFSREFLAYF
                     VLFLKDTAEVGLDVLMDFLEDPEAEEFVMEWNQEVFEEGKVGLEEGEFYPYPRY"
     gene            complement(12159..12611)
                     /locus_tag="VQ664_001783"
     CDS             complement(12159..12611)
                     /locus_tag="VQ664_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HET2789897.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            complement(12648..12827)
                     /locus_tag="VQ664_001784"
     CDS             complement(12648..12827)
                     /locus_tag="VQ664_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HET2789898.1"
                     /translation="MPMTQKEMVKLFTAHGWIKTRGGKGSHIKIEKQGERPITILHGE
                     LNKYTERGIGKQAGL"
     gene            complement(12964..13143)
                     /locus_tag="VQ664_001785"
     CDS             complement(12964..13143)
                     /locus_tag="VQ664_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789899.1"
                     /translation="MNLIFEEYQFVKIGDKKYRVRSGPMIHSTPPQSVLDRDTFTIDY
                     TDDELLDKEAVFTTH"
     gene            complement(13308..>13493)
                     /locus_tag="VQ664_001786"
     CDS             complement(13308..>13493)
                     /locus_tag="VQ664_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789900.1"
                     /translation="IFTKQIRHWILSDQVISGKRKLFFREDTPKEILDLYENIKSKLD
                     FAYQEVHSNNGLKKYEK"
BASE COUNT         4016 a         3071 c         2451 g         3955 t
ORIGIN      
        1 gcactcgttg atgcggaagc tgacgcactc gttgatgctg aggctgaggc acttgtactt
       61 gctgaggctg atgcgctggt tgaggccgat tcagaagctg aggtgcttgc tgaggctgag
      121 gcgctttgac tagcacttac tgagagtgac ttagactgtg aaagtgactg actggtcgtg
      181 ctagattcaa ctacctttcc tctacccttg aagtagttag ttctaatgtt atctgtttta
      241 gcagcgtaag gggtaaatgt aaaggatgta tccgttccag taattggtac agtccaagat
      301 gatgttaatc catatccttg cttagcaaag aaaccattca tttgggcacc atttccccaa
      361 gtatacccac taccccacgt cgtcattgta gatgtattat aggatcgaac cagtacacca
      421 tctttgtcag taatgtagtt ctttacatct gaaggggtac caagatcact gccaagggtt
      481 aacattgttt gtattgaagt acctgtatta tagatagaat acccatgacc catctttgaa
      541 agattaccaa gagcccttgt ggtaggatct acatacgtaa ccgtataggt aaaggtcagt
      601 tttgaaccat catttgtcac tgtcaattta tagtaaattg gaacatgata taccgaatct
      661 aaacctgtac ctgtataaac ttttgtctca cttttagcaa tgtttagact tgcattaatt
      721 gcaggggcgc catttacaat cgtattgcca gaaaaaacag cagcttttat agaagccagc
      781 aattgctcga tggaatccac tgaacgcttg cgtcgcttag cataagattg gagattgaca
      841 tttgtaactg atgctgcata atcactagct ggtttcttac gatcttcttc gaccttctta
      901 gcagttgctt ctgtagcggc agctgtttgt gatcctacca cagtagatga tgcagagata
      961 cttgtcgaag ccgatgtact tgctgattct gatgcacttg tactcgctga ggtcgaagcg
     1021 ctggttgagg ctgactcaga tgcagatgta cttgccgact ctgaagctga caaactagtt
     1081 gaactcgctg aattacttgt agatatcgta cctagaacta ctgtatcatt tgttgccaaa
     1141 gcatccgttt tctctacagt tttttcaagt actgccgact catttgtaaa taccttcgtt
     1201 tgagttgcaa cggttccact tatgacagtt cccgcagcaa ctattccctt gaggatatca
     1261 agcccagtaa ttgaatgact tactttatct tctaccgttt cggtcatgac ctgagtagta
     1321 tcaacaccac cacgcatgac cttaaacaag ccaaaaagag aagtcgaggc ccgtagccaa
     1381 tgcttccctg atttgattaa tttgaaccga gttactcggt ctgtttctct atattcaccc
     1441 ttctgacgtc taaaaaatat tttgaaattt cctttcgagt attattttca tgtatggata
     1501 taaataaatt accatactat aattatagaa tagggaaccc aaaatagcaa gaaacttgag
     1561 gtatttttgc taaaaaaaaa aagcatttta ctattttata tatatattat aagataagtt
     1621 ttttataaag acacgcaaat gagtataaat cagctaattt ttggtttata ttcctatttt
     1681 tatgcataat tattctttca ttctctaatt tgtgaatcaa tatatctgat tagaaaacta
     1741 ccattgagtt tttgctccac ctcattagtc cgctcaaaac gccgtccgct aatcttgtca
     1801 tagactttct cccctctagg agcccctgca taaggacgat agaggtagcg gttgattccc
     1861 gtttcgtcaa tatataggac tggtaaatct tttaggttat ccaaaatatc aagaaactca
     1921 gaaactttct caggcttttg ttccctaaaa ctggtcgtct tttttaaaat gaccttaatc
     1981 tgctttaaaa ctgcccatac ggagggcaaa gcacaatcaa aacgggccgc aatttcccgt
     2041 aaaaaagcgt ctggatgagc ctctacaaag gctttcaatt cttctaaagg gatcttacgc
     2101 tttttgacga ctcgcttttt ccgctctaag ttcccttgtt tacgtctttc ttttcccacg
     2161 tgaagagagt tctgacgcca acaccaaaaa acttggctgc ctcgacatga ctgtgcccct
     2221 ctttgatgga atctaatgct ccttgtttaa aatcagtact atatgccata gctttattag
     2281 accatgctta ttttaaacta agcaactata gatagagaaa tgaaataaaa tctaaattcg
     2341 aatgtgataa ggagttagaa attgaaacaa taggattccc ccattattca cacaaaaata
     2401 aaaccactaa aaaacagagc ttgccagcat tcttgaaaag tagtataatt attgcatgcg
     2461 caatcatctt gtgacgcaga gactgcccgt taatggactt tcttctatat tatgactcta
     2521 aaaagaaagg agacactatg acctatttgg aaaaatggtt tgacttcaat cggcgtcaga
     2581 aagaaattga aagtctcttg gaagagacca ttgcccaaca gagcgagcaa agtctgacct
     2641 tgaaagagtt ctacctgctc tactatctgg acttggctga agaaaaatct ctacgccaga
     2701 ttgacctgcc agataaactt catctgagcc cgagcgcagt ttctaggatg gtggctcgct
     2761 tggaagctaa aaattgcggt ctactcagtc gcatgtgttg ccatcaagat agacgctcta
     2821 gttttatctg cctgacaaat gatgggcaaa agacactggc ctcgctacaa aagactgtcg
     2881 aagaaagctt ggaagcaggt ttggatttct tgatttaaga tgattttaaa aaaagttgcg
     2941 tgcgcaatca tttttcttga cattctcttt tataaggagt aaaataaagt tagcattaaa
     3001 caaaggagtt ttaaatatga ttgaaattac ctatatagat gccagcaaga acgaaagaac
     3061 tgtgactttc gagtcttatg aagactttga acgttcacaa caagcttgcc ttatcggcgt
     3121 cgcagactac taccctgtcc aaaaattaac ttacaagggt cataatttgg actaccatgg
     3181 gacttatgga gatatcttct tctatctcat gaaacaagat ttaagccaat ataactaaaa
     3241 aaaggagaaa tacaatggca aaagcaatta cagatgcaac attcgaacaa gaaacaaaag
     3301 acggtttggt cttagtagac ttctgggcaa cttggtgtgg tccatgtcgt atgcaaggtc
     3361 caatcttgga caaattgtct gaagaacttt cagaagatgt cttgaaaatc gttaaaatgg
     3421 acgttgatga aaatccaaac acagctcgtg cttttggaat catgtctatt ccaactcttc
     3481 tcttcaaaaa agacggccaa gttgtcaaac aagttgcagg tgttcacaca gcagaacaaa
     3541 tcaaggccat cattgctgaa ttgagctaat caaacgagag accaagtact ttctttggtc
     3601 tcttttttct tgccctttgc catttttcaa aaaatatgct agactatagt agattgaaac
     3661 tagaatagta cacctctact tctaaaacat tgttaaaaat cgatttgact gtcctgatcg
     3721 atttgtcctg tttttatttc attttactat ataagtagaa tattacgatg tttgggatat
     3781 gccatcgcta aaaaaaaact cgatttggta ttttttagtt ccctaatggg agctttttgc
     3841 gtgctctgaa catttcccat tttggaagga gtactatgaa acatcaatca gccttggtcg
     3901 tctttagtgg cggtcaagat tcaacaacct gccttttctg gaccatgcaa cactatgaaa
     3961 cagtcgaagc tgtcaccttt gcctacggcc aacatcatca cctcgaaatt caaattacta
     4021 gagaaatcgc taaggaacag ggcattcgtc accatatcct cgatatgtct ctgctgggac
     4081 aaatcactgc tcagccagac tttgcgacga ttcatatttc ctacattcct gacaagctct
     4141 gtgtcgagtc aaaatccctc aaactatatc tatttagcta ccgaaaccac ggagatttcc
     4201 acgaaaactg tatcaacacc atcgggaaag acttggtcaa cttgctagac cctcgctatt
     4261 tagaagtctg gggaaaattc actccgcgcg gtggcatttc aatcgacccc tactataact
     4321 acggtaagca aggaactaag tatgagggct tggcagaaca acgcctcttc caacacgacc
     4381 tttatccaga gaaaattgac aaccgctaaa gtcatactca atgaaaatca aagagcaaac
     4441 taggaagtta gccgcaggtt actcaaagca gtgtttgagg ttgtagataa aactgacgaa
     4501 gtcagatcaa aacactgttt tgaggttgtg gatagaactg acgtagtcag taaccatacc
     4561 tacggcaagg taaagctgac gtggtttgaa gagattttcg aagagtatca tacgaaaaag
     4621 ccctgttcct caagatgagg agcaaggctt tttgagtttc aattattctt ctgttccaag
     4681 gaaatttttt gcaacaaggg ctgcaagaac tccaccagcg attggtgcaa ggatgaaaat
     4741 ccaaacttgt tgaagggctg cgccgcctac caagacagct ggtgccaagc tacgagctgg
     4801 gtttactgaa agtccagtaa tcttcaatcc gacaagaatc atcgccatca atgacaaacc
     4861 gattaccaaa ccagcaatcg cgccattgcc cttgctttct gaagtcacag tcatgataac
     4921 caatacaaac aagaaagttg cgatgacttc aaacaagaaa ccaccaaaga cagtgacacc
     4981 gtttgccaag gcattttcac caagactagc agttgacata cctgaattac tcaagaggaa
     5041 gaagactgcg ccagaagcga tgaaagctcc aacaacctga ccaaggatgt agtttacaag
     5101 ttctgaagat gacaaacgtt tgtttacaaa catagcaatc gaaacagccg ggttcaagtg
     5161 agcacctgaa acagttccga ttgagtaggc tgccaccacg attgccaaac caaaggcaaa
     5221 ggcgattcca aggtgaccaa ggccatcaag accatttcca aaaacaacag ctcctgttcc
     5281 aacgaacaca agcatgaacg taccgattaa ctcagcaaca aattttttca ttttctttct
     5341 ccttttttca aaaactagat actagtctat caaaagtagg aaagggtttc aagaaaattg
     5401 attggaaatt ttttgaaaat catagaacta ttagctaatc tctagtattg aaaagactgg
     5461 atagcttctt tcaactcatc ttgtaaacta tttctctggt caagttggac atagacttcc
     5521 accagacagg atctaaagtt ggaaaatttg taaaaatcct ccctttcttc tatcggaaaa
     5581 tcaacagttt ttatccaaga agctacttgt tcttgcgcta acttcccttg taaaataggt
     5641 tcatagatca ctcttgctaa acgccaatcc tcatcatctg taaagcgaat cgacattctt
     5701 ttaaataatt ggccaagtat ctcaaatact tcatgaactc tgtttttagg aaagcccgga
     5761 tgacaaacca cctctgtcag taaatcggct ccatgtgcaa aagcatgaac ccaaccatac
     5821 tgacttgaaa aaccccttgt atccttttct tttgaaagat agtgcaagcc ttgatttaaa
     5881 aggacattac gaatttctgg agaaggattt cccaaatgat caaacaacca ctggatttct
     5941 tcctggttat aatttggttt ttcttctgct atttttctta gtaaatcttg atacatggtc
     6001 aatacctcta catttctagc aactgttcaa aaaggcagtc ttaaatgact caatattgaa
     6061 ttctcaatta aatacaatct gatataaaat gacgtaaata actatcaata ccagttctac
     6121 agtaagttca aatttaacat cacgatcttc aacgacattt ttgaaaatag ctacaactaa
     6181 gacaaataga atgacgctta acaagcccat aaacatcatt ctaaaaaatt tttctattcc
     6241 cctactctcc caactcagca ctataggaga taatctggtc aactgtgtca gacaagaatt
     6301 ggatggtatc acggagtggt ttgtctgttg aaatatcagc accgataatc atggctgact
     6361 caagtggtgt cttgctacca cctgatttga ggagattgag ccagtcttca gctccagttt
     6421 cagaatgttt tagatgaagg taaccagcag tcgagataac tagtcctgct gagtaagtgt
     6481 aactatacaa gcccatatag tagtgagctt ggcgcatcca agtcagagtt gcatcatcgt
     6541 caatttcaat agcatctccc cagaaatccg tcaaaacttc cttcataatg ctgttgagct
     6601 tgcttgctcc aaaggtctcc ccttcttcaa tcaatgtata caccttacgc tggaaggcgg
     6661 cttccaagag gtgggtgata aagttatgga agtaggtgtc tgtcaagcga tgagccagag
     6721 cgaagcgttt ttgacgtggg tcattagact ggttctccaa gtaatcactg agtagcaatt
     6781 cattgaaggt tgacggtgct tcaacatagt aggtcgacat atgggcattg aagtaacttt
     6841 gatgattgtc tgaaaagatg aattgaccag aatgcccgat ttcatgaatc aaggtataga
     6901 catcgctcaa acggcctgtc cagctcatga gtacataagg gtgtacgcga tatgggtccg
     6961 ccgcataacc accggaatcc ttgccactgt tagcagcaaa gtccacccag cgctcttctt
     7021 ggtaacgagc aacttcctga caatattctt gccccaaagg ttctaccgac ttcatgacca
     7081 aatcataggc atcgtcaata gtcacttcag gattcagggc gctgtccaag tccaatttcc
     7141 agtctgcaaa ggtcatcttt tcaagaccat ttaccttggc aacatgcttg aggtatctct
     7201 gagcgactgg tgcaaagtcc ttcatgatga ggtcaatctg gcggtcaaac atgacacggt
     7261 ccacttcttg ttcagctaga agatagtcaa agacagagtc gtatcccttc atatcagcca
     7321 agagtttttc agacttgacc tgagccagat aggctgctgc agccgtattt tggtgcttac
     7381 gaagtccctc tgagaaggaa cggaaggatt tctcacgaac ctcagcatcc tcatggtttt
     7441 ggtagaaatt ctcataggtc acaaagctgt ttttgtaggt cttgccatgg gcttcaaagt
     7501 cagccatttc aaaatcccca gctcgcatct tagtataaat gtcctgcgga ctgtagaaaa
     7561 cttcaccgag atttgtcaag gccttctcca catctgcccc taagtagtgg gcttttttga
     7621 ttttagcctg acgaatggca gctgttaaat gtggcaattt acccaaacga tccaagactt
     7681 cctcgtctgc tgccaccaag gcatcgtcaa aaaaggtcaa ggctacgctg gcatctgttt
     7741 caaattccat cccagcttga gcaatatttg caaattcgtc attgctatag tccgtcgtct
     7801 gaggcataaa accatagttg ccaatatggc tcatctgaat gtagatctgt tccaattccg
     7861 caaaggcctt ctcgaaatcc tcaaaagtgt gaagattgcc cttgtaatca cggctaaact
     7921 ggttgatgtc ttcgcgagct ttctcgattg cacgcaagaa atcctcacgg tcttggtata
     7981 gagctgttaa atcccaaagt tccttctctg gaaattctga acggtgtttt tgttccattt
     8041 tcttcctctt atttctctaa ttctactaaa acactaaggg ctgataaggc gtaaagcggt
     8101 gctgtttctg ctcttagaat gcgagggcca agtcctgcca aaacagctcc cttagcttca
     8161 aaattttcaa tttccgcagg tgacagacca ccttctggac caaagataaa gagcaatttg
     8221 gctcctttct cgagtccagt aactgctttt ataagagcag cggcttctcc ttctttggcc
     8281 gcctcttcat aggctactaa gatgcggtca aactggtcaa gttgggctag aaagtctgct
     8341 ttattctcga aaagatggat acttggaaca acattacgct tactttgctc tgctgctcca
     8401 agagcaattt tttctagttt ttcaaccttt ttacccaatt tcttgccatc ccacttagca
     8461 acggaccaat cggcagggaa ggcccaaatc tggctggcac ctagttccgt caccttttga
     8521 gtgataaact ccaacttatc tcccttggga aatccagatg cgatggtcac ttggactggt
     8581 agttccacat tgtcatttaa ttcttggacc aactcaaact gacgattttc catatccagc
     8641 acgcgcgcca agcgcttgat gccatcatca aagactaagg taacctcatc ctcttctttc
     8701 aagcgcataa cctgaaacat atgcttgctg gtttccctgt cctcgatggt gacaggagag
     8761 actgcactcc ccttgacaaa atactgttgc atgctagcct ccaatcacac ctgaaatatc
     8821 cttggtcttc ttgaagacgc aggcattcca ttccccttga atcatatggg tttcaaggaa
     8881 aaatccagct gactcagccg actggcgcac catgtcccac ttgtccttga taatgccact
     8941 catgatgagg tagccttcat cctttaccaa gcgataagca tcctccgtca gatgaatgag
     9001 aatatccgcc aagatattag ccacgatgac atctgcttca atctcaactc ccttaagcaa
     9061 gtctcctgct gctacatgga tattttccat accagtgttg agctcaatat tttcctgagc
     9121 gacacgaacc gccacatcat ccaagtcata ggcgaaaatc tccttggcac ctaggagtga
     9181 gcttgcaata gaaagaaccc ctgaaccagt ccccacatct agcaccgttt cgccaccacg
     9241 aagaacctgt tccaaggcaa aaaggctcat cttggtagtt gggtgggttc cagtaccaaa
     9301 agccatgcca ggatccagct tgataatttt ttctcccgca gtcgcctcat agtctgtcca
     9361 agagggaacg atggtcaaat catgagtgat gcgagcaggt tcatagtatt tcttccagtt
     9421 gtctgcccag tcttcctcag ccaaggcagt cgtacctatt tttaactctc ccaaatccat
     9481 aaaatccgtc aattctgcta agcgagcctg caagtccgcc tcaaccactg tcatatccac
     9541 cgtgtcaggg tagtaggctg tcactacgat ttcttcttgc tgctccacct ctgggaaaat
     9601 ctcgccaaaa cgatccacat ttcccatata gtccatgctg tcttcaatcg cgactccttg
     9661 cgctcccagc tcaatcaaga gattggaaac caactcctct ccctcacgct tcactgtaac
     9721 ttttaactct tgccatgttt ccattattaa gataccaagc ccgtaaaaca caaaaccaaa
     9781 ataggaaatt ctctgaagac gcttgtgtct aagagaagtt tatctttttg gcacagtgtt
     9841 tagggcgggt tcagtttaga aatgtaactg aaccatcctt tctaatcact tacttttaaa
     9901 taatctttta atctctcttg caactgaggc acaacttgac tggaactaag aaattcctca
     9961 acattcatca gctgatagcc ctgtccttca tctccgaaga tgatattgtc aaattgttct
    10021 tgtcttagct gaccaaccat aaagaccgat ttcttgcctt taaaaattac gctaggataa
    10081 atcttgctcc aaagcagaca gtcttcatct aaatgaattc ccagttcctc ataaacttca
    10141 cgccgagcgc attcaaaagg gctttcgtcc ccttcacggc caccacctgg caactcccac
    10201 atgttgggac aagggatatc gtccttgtca tcacgcaaaa tcgtcagtag cttatcccca
    10261 caaaagaggg caatcttgca accttggaaa tcagaaattt ctagttccat cttcagttcc
    10321 ttctaacatt tccttttcca gctctgctaa caagttttca taatagcgtt tctcgtccct
    10381 caacattcga ctactatcca ttttctgtct agcaatcttg agagccttac gagttcgatc
    10441 tacatctttc ttcaccttta attgatacca ggcttgtatc acttgaagat tggacagttt
    10501 gagagacaga aacgatttga cctgtcgaat actagcatat tgctccgctt gctcaaaatc
    10561 tccttccaac aaggcgatat gaagcaggga tagttgggca actgtctgca tcatcggagt
    10621 agttgtcctc tcaagtaatg cttgaaactg ctgtttagct acttcttcct tcccttccaa
    10681 aatggaaact tcaccttgca tacctaatac accatccgca aaactccctc gtgcatcctc
    10741 aggaactgct tgaacaaagt ctttcaaatc atattcttga ggagccagca aagtttgagc
    10801 agaatgtctc aataccaggt aggcgtattt ggtattttca gggtgttgta gtaattccca
    10861 aatttttgct ccatcggtga tgtcgactgg caaaatgtta tttaggaaga aagataaatt
    10921 aagaaaaatc caagtccctg caaaatacca gcttcttgtc aaaaatccaa acactatcgc
    10981 caataatatc aagccgagat gaaccatcaa gcctcctgaa agcatcagga tgattctttg
    11041 atcgctttca tcctctttta aaccaatgta ttgagcacca acatttttca gaatggctgt
    11101 tctactaaga tgaaacctgc ctgacttttt ggtcaaaata aaatgtccta atccaaaagc
    11161 caccagccga tagcctgtca agtagccaca aaaagcatga cccagctcat gaagaataaa
    11221 gattaaatac atgcttagaa gagcgaaggc ataaccaaaa gtaaaggcta aaactgcgga
    11281 ataccccaac tctgcaaatg cgattgttcc acaagcaaaa gctagcataa taaagacaac
    11341 agctagcaca taaaccaaat aagtcccaat tttcttcata acacctccaa ccaactccta
    11401 gtatcttgga taaggataaa attctccctc ttccaagcca acttttcctt cttcaaagac
    11461 ttcttggttc cattccatga caaattcctc tgcttctggg tcttccaaaa agtccatgag
    11521 gacatctagc ccaacctcag cagtatcttt aaggaaaagc acaaaataag ctaaaaattc
    11581 acgggaaaat ccttttttag gcaggtaagg aataacagtc aaatagtctt cctcattgac
    11641 tgttgactta gcaggattgt agaaaaggac cgcttcctca aaaagaatgt catctgatga
    11701 aacctctccg tcttcatcca ccatctccac acctgcagca ttttgcgctt ccaatagaaa
    11761 actcacttct accgcatggt tgcgtttgtc ccagctaatc tcaaagtcaa agggaaagtt
    11821 cttgtccaac tcttcctcta aaacatctaa aaatccgtat gttgccattt tgtcctcttt
    11881 ctatgcgact ctttaatcgc cccgattgct cggaaatatg ctaaaataga tactaccatc
    11941 ttaccacaaa attattttat gtcctaatta taccatatta cctcatttaa acccttggta
    12001 tcagtgattt tcttaaaagt ctgatttctt catttctcat aaaaatcaat ataaaaagcc
    12061 ctcgaaaggg ctaataaatc tataaaatca ataggcgagt aactagcaca agtggacgtg
    12121 cttttttatt gactattacc acgataccac gcttaatctt aggcttgaac tttcttatct
    12181 gcaatagcgt ctgtcaaagt ctgagaaaag ttaagtccca tttctcgtcc caacttatct
    12241 gcccattttg gtatggtcaa agtcttttta atgggttcct gacttcctag gtattctgat
    12301 acatcaacag ataccataga aataaaagat ttatcaaggt cataggttga cacgaaatct
    12361 tcatcatctt taaaaggatc attatcaatt aaagacaagc tattgatatc tgatggctga
    12421 ggtaactctc catcactctc tatcaaatct gcaacagtta tccctagcca ctccgacccc
    12481 atagccaaag cctcagaaat cccctctcct tgtgtagctg agtattcaaa atctgggaaa
    12541 tggacaaaat aagtcgcttc tgttccgtct gtgtcgtcat aataaaataa agctggatac
    12601 gtaactaaca tttcactacc tccatatcaa aaagcaggga ctgaatttta caacccagct
    12661 tgctttccta tccctctttc agtgtactta ttcagctcac catgaaggat tgtgataggt
    12721 ctttcccctt gcttctcgat tttaatatgg gagcctttac cgcctctagt ctttatccaa
    12781 ccatgggccg taaagagttt aaccatctct ttttgtgtca taggcatagc gcttttacct
    12841 cctgacaaca ccattataac acgtgttaca cgtattgtaa aggagtgata cttattattc
    12901 tattatacat aaaagcccct agatgtggtt ctaagggaaa ccaatttatt cagacctatt
    12961 tttctaatga gtagtaaaaa ctgcttcttt atcgagcaat tcatcatctg tatagtcaat
    13021 tgtaaaagta tctcgatcta agacagattg aggcggagtt gaatgaatca taggaccact
    13081 gcgtactcta tattttttat ctccaatttt tacaaactga tactcttcga aaatcaaatt
    13141 caaaccacgt caacgtcgcc ttaccgtact caagtacagc ctgcggctag tttcctagtt
    13201 tgctctttga ttttcattga gtatgattaa ctctcaagtc ttcgaaatca ggattttcaa
    13261 cagttattac aaggaggcga tttactactt caaaaacatc aattattcta tttttcatat
    13321 tttttcaacc cattattaga atgaacttct tggtaagcaa aatcaagttt agatttaatg
    13381 ttttcgtaca aatctaaaat ctcttttgga gtatcttccc ggaagaaaag ttttcttttc
    13441 cctgaaataa cttgatcact aagaatccaa tgacgaattt gttttgtaaa aat
//
LOCUS       DAVBIC010000056        12573 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.056, whole genome shotgun sequence.
ACCESSION   DAVBIC010000056 DAVBIC010000000
VERSION     DAVBIC010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12573)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12573)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12573
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.056"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            complement(251..433)
                     /locus_tag="VQ664_001787"
     CDS             complement(251..433)
                     /locus_tag="VQ664_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789901.1"
                     /translation="MAVIFKNVLIEEKTEEEKQHILSILNGEYDLSDDVSCRLRRLNE
                     ESKRLEVFVKETNSLV"
     gene            complement(649..1881)
                     /locus_tag="VQ664_001788"
     CDS             complement(649..1881)
                     /locus_tag="VQ664_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HET2789902.1"
                     /translation="MKIAVAGTGYVGLSIAILLAQHHQVVAVDIIPEKVELINKKKSP
                     IQDDYIEKYLAEKELNLVATLNAEEAYENADFIVIAAPTNYDPKKNFFDTSSVEAVIE
                     AVMKYNPDAIIIIKSTVPVGYTKSVRRKFLTDNIMFSPEFLRESKALYDNLYPSRIII
                     GTDKDDKDLVKSAEIFVKMLQEGAVKENIETLYMDFTEAEAVKLFANTYLALRVSYFN
                     ELDTYSEMKGLDTQAIIDGVCLDPRIGSHYNNPSFGYGGYCLPKDTKQLLANYSDVPQ
                     EMITAIVQSNRTRKDYIADRILDLAGSYVGNDFYKPDKEKEIVVGIYRLTMKSNSDNF
                     RQSSIQGIMKRLKAKGVTIIIYEPTLESGTTFYGSQVVNDFEIFKKSSQVIVANRFDE
                     TLEDVRGKVYTRDIFKRD"
     gene            complement(1910..2980)
                     /gene="gla"
                     /locus_tag="VQ664_001789"
     CDS             complement(1910..2980)
                     /gene="gla"
                     /locus_tag="VQ664_001789"
                     /EC_number="5.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001214397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucuronate 4-epimerase Gla"
                     /protein_id="HET2789903.1"
                     /translation="MRGKTILITGVAGFIGSNLVRKLLELEGTMTIIGLDNLNDYYDI
                     ALKDYRLLQLNKLIQDYPEKNWIFIKGDIADKMLINKIFKSYHPQIVVNLAAQAGVRY
                     SITNPDVYIESNIVGFHNVLEACRHSYEIYDGGVEHLVYASSSSVYGGNKKIPFATED
                     KVDNPISLYAATKKTNELQAYAYSKIYNIPSTGLRFFTVYGPAGRPDMAYFGFTDKLR
                     SGSDIEIYNHGNCKRDFTYIDDIVEGIVRVMQSAPKKLVGSDNLPLAPYKVYNIGNSK
                     PENLLDFVDVLQQELIKAGVLPENYDFDSHKKLVPMQPGDVPVTYADTSDLERDFGFK
                     PKTSLREGLRKFAEWYKDYYNV"
     gene            complement(3048..4217)
                     /locus_tag="VQ664_001790"
     CDS             complement(3048..4217)
                     /locus_tag="VQ664_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HET2789904.1"
                     /translation="MRLSKKYWFALTSKFLLILLTLLSSIIINRGLGVEKKGDYAYVM
                     NLVEIFYILGGVGLGQAYSTFKRNHSNEYQNKFVFLTFIQGLLFGIIGLIIVLADVPI
                     DYGGVIIVLSSLSIMRTNLTMIAVIENSIKRNKIVLGVSVVYSVMLVLLLLFHLVSIE
                     MVFLVYAINEFLRIILFLYYYNMFPVFEHISIKEFFTIYKFGFLSMILTLLITFNYSI
                     DIIMLKQMSSSYNVGIYSVAVTFSNMFLMVPDSFKEILFGDSAKRTFEKNKAINAIKV
                     SFLFMILLIIGFLSFGEFAITLLYGSSYIKAFPITLVIFLGSLSMIFFKILQPIYISQ
                     GKQSVAIKILSVSALINISLNWYLIPNYQITGAAIASAISYTVCGLFFIIDYLRN"
     gene            complement(4403..5707)
                     /locus_tag="VQ664_001791"
     CDS             complement(4403..5707)
                     /locus_tag="VQ664_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide repeat unit polymerase"
                     /protein_id="HET2789905.1"
                     /translation="MKFSLQSNDIKNKIILLVGVVFSGTLILCSENNDVTIPLFSMIF
                     LSFMAMIIVKFNIFHPYVWYSSFFTIYSISYPLLYRMEYINYGYTKDLIFMQWLALAT
                     LLLTLPSKAIVLSERKINLNNNNYLLFLNNMNTFITTVAIIYLLGSGFRNKGEIYSGA
                     NIVIMLVFSLVYFMILIHTYQLFIQLSTKKWRLLNCNTNTAIVICLFSIVTGERDYMF
                     TLFILDVIILFYFHKIKRFYLVMLVPLAALLIPLSAVFKYTLLSGQVSSINTNNIWFD
                     LLDGEFVSASRNLQILILHNMGNYFEGRSFFNDIVRIFYNTGYSNQTWFMDTFFPNVH
                     STKYGFTLVGEGYVNGGYFGIVMIFMLTGFLMRFLYINAQRNIYGMLIYLYMIPIFIY
                     STRADFANILSPLLKYAILGTLVIVFINRMVLISPLDEMGGE"
     gene            complement(5824..6978)
                     /locus_tag="VQ664_001792"
     CDS             complement(5824..6978)
                     /locus_tag="VQ664_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HET2789906.1"
                     /translation="MKVFIATEFRCTIYKNEIYLKPKAYFIYERYAKAFGEIVLCSRY
                     EKVESYPEGYHKANFINKFIPIEGLHQVLFGQNKNKIIEGMIDSDLIVVRIPSIIGSK
                     TADYALKIGKPYLTEIMGDAWDSYWYHSLKGKLLAPYIYAKTKSIVKNANYCIYVTEK
                     YLQDRYPNIKSNIVASNVNITSVENRSLKSRLYKLKKFNPQKISIMTTASVNVRAKGH
                     RFVLEAMKRLEIQGILLDYYLAGDGDQSFLKKKAEELGVANRIHFLGELTTSQIYEYL
                     DKVDLYIQPSLQEGLPRAVIEAMSRACPCIGSNKAGIPELLGPHCLFTPSSSQAIAGS
                     IIDFISMDKEKMVIKQFEFSKKFLSSVLNKRRSDYFAQIRRELNNSDGLD"
     gene            complement(6975..7526)
                     /locus_tag="VQ664_001793"
     CDS             complement(6975..7526)
                     /locus_tag="VQ664_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HET2789907.1"
                     /translation="MNRIIKNIVGLLRANICLILLKVCRNKDLTFHYFLKFGKNVTVE
                     QESNAKLILGKKIRVNAGGVLKVRKGAKLKISDDVFLSNNCMIACRKYIDIKSGVKCG
                     PGVLIYDHDYDVSVPGGLKAKKFKTAPVMIGENVWIGANSIVLKGVSIGENSVVAAGS
                     VVTKDIPADTIFIQKRLSREMKL"
     gene            complement(7519..8655)
                     /locus_tag="VQ664_001794"
     CDS             complement(7519..8655)
                     /locus_tag="VQ664_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001053205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HET2789908.1"
                     /translation="MNLQKKKIMLITNHDDDIYCFRKEVIESLVEYGYEVLVSCPYGD
                     KIELMKSIQFEYEDITIDRRGINPLKDIRLFLSYIRLLRKYRPDVVLTYTVKPNVYAS
                     LAATILGIKYINNVTGLGSVLTMGSCVRSLVLLLFRISFRKSNCVFFQNEYNMKMLKT
                     LGLILGDSKLIPGSGVNIEKYPVQQYPNGGNGIQGETIVFNFIGRILKEKGIDTYLAA
                     AQIIKSRYPKTEFNIIGFIEPTESNYELKICDLEKKGIVYYLGQQKDVIPHITRSHAI
                     IHPSVYGEGMSNVLLENASSGRVLITTDNPGCKEIVKDRETGYIFQGGNVEELVSILE
                     VFLGLENEKRKEMGLQGRMYIEQYFSRQIIIDAYLDKIKGALDE"
     gene            complement(8796..9461)
                     /gene="cpsD"
                     /locus_tag="VQ664_001795"
     CDS             complement(8796..9461)
                     /gene="cpsD"
                     /locus_tag="VQ664_001795"
                     /EC_number="2.7.10.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis tyrosine autokinase
                     CpsD"
                     /protein_id="HET2789909.1"
                     /translation="MPTLEIAQKKLEFIKKAEEYYNTLCTNIQLSGDKLKVISVTSVN
                     PGEGKTTISVNIAMSFARAGYKTLLFDGDIRNSVMSGFFKSREKITGLTEFLSGTADL
                     SHGLCDTNIENLFVVQSGSVSPNPTALLQSKNFNDMIETLRKYFDYIIVDTPPIGIVI
                     DAAIITQKCDASILITATGEANKRDVQKAKQQLEQTGELFLGVVLNKLDIPVDKYGVY
                     GRK"
     gene            complement(9471..10163)
                     /gene="cpsC"
                     /locus_tag="VQ664_001796"
     CDS             complement(9471..10163)
                     /gene="cpsC"
                     /locus_tag="VQ664_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     CpsC"
                     /protein_id="HET2789910.1"
                     /translation="MKEQNTLEIDVLQLFRALWKRKLVILLVAIITSSVAFAYSTFVI
                     KPEFTSTTRIYLVNRNQGEKPGLTNQDLQAGAYLVKDYREIVLSQDVLEEVISDLKLD
                     LMPKGLANKIKVTVPVDTRIVSVSVSDRVPEEASRIANSLREVAAQKIISITRVSDVT
                     TLEEARPAISPSSPNIKRNTLIGFLAGVIGTSVIVLLLELLNTRVKRPEDIENALQMT
                     LLGVVPNLGKLK"
     gene            complement(10172..10903)
                     /locus_tag="VQ664_001797"
     CDS             complement(10172..10903)
                     /locus_tag="VQ664_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein phosphatase CpsB"
                     /protein_id="HET2789911.1"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLAESYRQGVRTIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVADDLVIAYGAEIYYTLDALEKLEKKEIPTLNDS
                     RYALIEFSMHTSYRQIHTGLSNILMLGITPVIAHIERYDALENNEKRVRELIDMGCYT
                     QINSYHVSKPKFFGEKYKFMKKRARYFLERDLVHVVASDMHNLDSRPPYMQQAYDIIA
                     KKYGAKKAKELFVDNPRKIIMDQLI"
     gene            complement(10905..12350)
                     /locus_tag="VQ664_001798"
     CDS             complement(10905..12350)
                     /locus_tag="VQ664_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HET2789912.1"
                     /translation="MSRRFKKSRSQKVKRSVNIVLLTIYLLLICFLLFLIFKYNILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLLFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSKIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     VNQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADS
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKMIDLLGGVDVHNDQ
                     EFSALHGKFHFPVGNVHLDSEQALGFVRERYSLTDGDRDRGRNQQKVIVAIIQKLTST
                     EVLKNYSSILQGLQDSLQTNIPIETMIDLVNTQLESGGNYKVNSQDLKGTGRMDLPSY
                     AMPDSNLYVMEIDDSSLTVVKAAIQDVMEGR"
BASE COUNT         4237 a         2432 c         1656 g         4248 t
ORIGIN      
        1 aattcactta cttcatatta catttagcat gaaatgaaat aagcgaattc tactttgttt
       61 gcatacaatt aaaaatcaat tcctaaggat gttttaaata actgtgtaaa aggcataatt
      121 tcaccatttc ttagtttttc aatgctaaat tacatagtaa ctggagagct attagaaatc
      181 tctaacttcc tcatagttaa aaaatgacaa tgagatactt attgatttca attcattaac
      241 agaatacgaa ctagacaagt gagttcgtct ccttaacaaa cacttccaag cgtttacttt
      301 cctcattcag tcgtcgtaat ctacaactta catcatcaga taagtcatac tcaccattta
      361 gaatagatag aatatgttgt ttttcttctt cagtcttctc ttcaataagc acatttttaa
      421 aaattactgc cattatcagc acctcacttc gaaggaatat atgcaactat atcctattaa
      481 gtcaatctct actgacaaaa gaagtatatt tacttcacta agtgcgagcg agaatataga
      541 aatatcttta ttgttttaga tgagttgtcg ctatcctcca gctagttttt aactattcta
      601 tcattcaaat gatatagatt attagggact agaaatatac aaattgattt aatctctctt
      661 aaaaatatcc ctagtataaa ctttacccct cacatcttct aaagtctcat caaaacgatt
      721 tgcaacaatc acttgactag atttcttaaa tatttcaaaa tcattaacta cttgactacc
      781 atagaaagta gtaccacttt caagagttgg ttcgtaaata ataatagtaa caccttttgc
      841 tttcaaacgc ttcataatac cttgaataga agattgtcta aaattatctg aattactttt
      901 cattgttaaa cgataaattc ctacaacaat ctctttttct ttatctggtt tatagaaatc
      961 attgcctaca taagatccag caagatctaa aatacgatct gcaatataat cttttcttgt
     1021 ccgattactt tgtactatag ctgttatcat ttcttgtgga acgtcagaat aatttgcaag
     1081 aagttgcttg gtatctttag gaagacagta acccccataa ccaaaagaag gattattgta
     1141 gtgagaacct attctcggat ctaaacaaac tccatcaata atcgcttgag tatctagtcc
     1201 tttcatctca gaataagtat ctaactcgtt aaaataggaa acccggaggg caagataggt
     1261 attagcaaaa agttttactg cttcagcttc tgtaaaatcc atatacaatg tttcaatatt
     1321 ttctttcact gcaccttcct gaagcatttt tacaaaaatt tcagcagact ttaccaaatc
     1381 tttatcatct ttatctgtac ctataataat tcgactcgga tataggttat catataacgc
     1441 ttttgactcc cgtaaaaact caggactaaa cataatattg tctgtaagaa atttcctccg
     1501 tactgacttt gtatatccaa caggaacagt acttttaatt attataattg catcaggatt
     1561 atatttcata actgcttcaa tgacagcctc gactgaagat gtatcgaaaa aatttttttt
     1621 cggatcataa ttagttggag ccgcaataac tataaaatcc gcattctcat atgcttcctc
     1681 tgcattcaat gtagctacga gattcaattc tttttccgcg agatattttt ctatataatc
     1741 gtcttggata ggggacttct ttttattgat taactcaact ttctcaggaa tgatatctac
     1801 ggcaacaact tgatgatgtt gagccagtaa gattgcaata gataatccaa catatcctgt
     1861 acctgctact gctattttca taattttttc ctttctcaaa acactctcgt tatacattat
     1921 agtagtcttt ataccactct gcaaactttc tcaaaccttc tcgtaaagaa gtttttggtt
     1981 taaaaccaaa atctctctct aaatcacttg tatctgcata agtaacagga acatcgcctg
     2041 gttgcatagg aactaatttt ttatgactat caaaatcata attttccggc aaaactcctg
     2101 ccttgattag ctcctgttga agaacatcca caaaatctaa caaattttcg ggtttactat
     2161 tcccaatatt gtacacttta tatggggcta acggtaaatt atcagatccc actagtttct
     2221 tcggagctga ttgcatgacc cttactatcc cctcaacgat atcatctata taagtaaaat
     2281 ctcgtttaca attaccatga ttataaatct caatatcgga accacttcgc aatttatctg
     2341 taaatccaaa ataggccata tctgggcgcc cagcaggacc ataaactgta aaaaagcgta
     2401 agcctgtcga aggaatattg taaatctttg aataagcata cgcttgaagt tcatttgttt
     2461 ttttagtcgc agcatatagt gaaataggat tgtctacctt atcttctgtt gcaaacggga
     2521 tttttttatt tccaccatat accgatgagg acgatgcata aactaagtgt tccacaccac
     2581 catcatatat ctcatacgaa tgacgacaag cttccaacac attatgaaag ccaacgatat
     2641 tactttctat atatacatct ggatttgtaa tggagtagcg tactcctgcc tgggcagcta
     2701 gattaacaac aatctgagga tgataactct taaaaatctt attaataagc attttatctg
     2761 caatatcacc cttgataaat atccagtttt tttctggata atcctgaatt agcttattaa
     2821 gttgaagcaa tcgataatct ttaagtgcaa tatcatagta atcattcaaa ttgtccaaac
     2881 caatgattgt catcgttcct tctaattcca ataatttcct aaccagattt gatccaataa
     2941 aaccagctac tcctgtaatt agaattgttt ttcctctcat atcataatac ctcttgttat
     3001 ttttatattt tcgtccacta atacacattc tttaacaact attataatca atttctaaga
     3061 taatctataa taaaaaacaa accacataca gtataagaga ttgctgatgc tatcgcagct
     3121 cctgtaattt ggtagttagg aattaagtac cagtttaaac ttatatttat caaagccgac
     3181 acagataaaa tttttatagc tacactctgt ttaccctgag atatataaat tggttgtaaa
     3241 attttaaaga aaatcatcga taagcttcct aaaaaaatga ctaatgttat aggaaatgcc
     3301 tttatataac tggaaccata aaggagcgta atcgcaaatt ctccaaaaga aagaaatcca
     3361 ataattaata aaatcataaa tagaaatgat acttttattg catttattgc tttatttttc
     3421 tcaaaagttc ttttagccga atcaccaaat aaaatctctt taaatgagtc tggaaccatc
     3481 aaaaacatat tagaaaacgt aactgcgaca ctgtatatac ctacattata actactagac
     3541 atttgcttca acattatgat atcaatacta taattaaatg taattaatag agtaagaatc
     3601 atagaaagaa atccaaactt atatatagtg aaaaattctt taatactaat atgttcaaaa
     3661 actgggaaca tattgtaata gtataaaaat aaaatgatac gtaaaaattc attaatagca
     3721 tataccaaaa ataccatctc tatagaaact aaatgaaata gtaacaacaa tactagcata
     3781 acggaatata ctacgcttac tcctaataca atcttattcc tctttatact attttctatt
     3841 actgcaatca tagtaagatt tgttctcata atagatagac tggacaaaac tattattacc
     3901 ccaccataat ctatcggaac atcagctaaa actattatta aacctattat tccaaacaat
     3961 aatccttgaa taaaagttaa aaaaacaaat ttattctgat actcattaga atgattcctt
     4021 ttaaaggtcg agtaagcctg acctaaacca actccaccta aaatataaaa aatttctact
     4081 aagttcatta cataggcata atctcctttt ttttcaacac ctaatcccct attaattata
     4141 attgaggata aaagtgttaa taagattaac aaaaatttac tcgttaaagc aaaccaatat
     4201 ttcttagata gtctcactta ttttctccgt atgttaaatt ttataacagt aaatttaaaa
     4261 ttatagtata ttgaaataga atatgaacaa aacgattagg gaatttaaag taatttataa
     4321 aaattcttta gaagctgcat tgtactactc caacttcaaa ccactatagt atcaaaaagt
     4381 ataccccacc tttttaaata aactactcac cacccatttc atccaatggt gatatcaaca
     4441 ccattctatt gataaaaaca ataaccaatg ttcccaatat agcatattta agtaatggag
     4501 ataatatgtt agcaaaatca gcacgagtag aataaataaa aataggtatc atatacagat
     4561 atatcagcat cccgtatata tttctttgag cgtttatata aagaaatctc atcaaaaagc
     4621 ctgttagcat aaaaatcatt acaattccaa agtatcctcc attcacatat ccctctccca
     4681 caagagtaaa accatatttg gttgaatgta cgtttggaaa aaaggtgtcc ataaaccaag
     4741 tttgattaga ataccccgta ttataaaaaa ttcttactat gtcattaaaa aaagaacgac
     4801 cttcgaaata attgcccata ttatgtaata tcagaatctg taaattacga ctagctgata
     4861 caaactcacc atctagcaaa tcaaaccaaa tattatttgt atttatagat gaaacttgcc
     4921 cacttaataa agtatattta aaaactgcag ataacggaat cagtagtgcc gcaagcggaa
     4981 ctaacattac aagataaaaa cgttttattt tgtgaaagta aaataatata atcacatcaa
     5041 ggatgaataa agtaaacata taatctcttt cccctgtaac gatagagaag agacagataa
     5101 ctatcgctgt gttagtatta caatttagta gtctccattt tttagtactc aactgtataa
     5161 atagctgata tgtatgaatg agaatcataa aataaaccaa agaaaatact aacattatca
     5221 caatattggc acctgaatat atttcccctt tatttctaaa accacttcct aatagatata
     5281 taattgctac tgttgtgata aacgtattca tattattgag aaataataaa tagttattgt
     5341 tatttaggtt tattttcctt tcgcttaaca caatggcttt agaaggtaga gttaacaaca
     5401 aagttgccaa agccagccat tgcatgaaaa tcaaatcttt tgtataacca tagtttatat
     5461 actccattct atagagtagc gggtaagaaa tagaataaat agtaaagaag ctactatacc
     5521 acacataggg atgaaaaata ttaaatttca caattatcat tgccataaaa cttaaaaaaa
     5581 tcattgaaaa taatggaatt gtaacatcat tattttcact gcataaaatt aaagtccctg
     5641 aaaaaactac acctactaga agtattattt tattttttat atcatttgat tgtagactaa
     5701 acttcattta cttttttcct ttaactaata atttaaacgt aatgcgtatt caaaaatttg
     5761 attggctatg tagtcagttt ttatagcata tttaatatat cgaaacggat tttccatcgc
     5821 attttaatct aaaccatcag aattatttaa ttctcttcta atttgagcaa aatagtcact
     5881 tctgcgttta tttaatacac tcgaaagaaa tttttttgag aattcaaact gttttatcac
     5941 catcttttcc ttatccatac taataaaatc tataatagat cccgcaatcg cttgtgaaga
     6001 ggatggagta aatagacaat gtggccccag caactctgga attcctgctt tattagaccc
     6061 tatacaaggg caagcacggc tcatagcttc aattaccgca cgaggtaacc cttcttgtaa
     6121 acttggttgt atatataaat caactttatc caaatactca taaatttgtg atgtagtcaa
     6181 ttcccctaaa aaatggattc tattcgctac tcccaattcc tctgctttct tttttaagaa
     6241 actttgatca ccatcacctg ctaaataata atccaacaaa ataccttgta tttctaatct
     6301 cttcattgct tccaatacaa atctatggcc cttggctcgt acattcacag atgctgttgt
     6361 cattattgaa attttttgag gattaaattt tttcaactta taaagacggc tcttcaaaga
     6421 tctattctct acagaggtaa tattaacatt tgaagcaacg atattagatt taatattagg
     6481 atatctatct tgtaaatatt tttctgtcac gtatatgcaa taattagcgt tttttacaat
     6541 tgatttagtt ttggcgtata tatatggagc taataatttt ccctttaaac tatgatacca
     6601 gtaagaatcc caagcatccc ccattatttc tgtcagatac ggcttaccta tcttcaatgc
     6661 gtagtctgca gtttttgatc caattataga cggaatacga acaactatta agtcgctatc
     6721 aatcattcct tcaataatct tatttttatt ttgaccaaat agaacctgat gtagaccttc
     6781 tatagggata aatttattaa taaagttcgc tttatgatat ccttcagggt atgattccac
     6841 cttctcataa cgactacata gtacaatctc tccaaatgct ttagcatagc gctcataaat
     6901 aaaataagct ttcggtttta aatatatttc atttttatag attgtacatc taaattcagt
     6961 cgctataaat actttcataa tttcatctcc cttgataaac gtttctgaat aaatatagta
     7021 tcagctggaa tatcctttgt tacaacactt cctgctgcaa ccacactatt ctcaccaata
     7081 ctcactccct tcaagacaat gctgttagct ccaatccaaa cattttctcc aatcataact
     7141 ggggccgtct taaatttttt tgctttcaat ccacctggaa cactaacatc atagtcatga
     7201 tcatatataa gtactccagg accacatttt actccagatt taatatctat gtatttacga
     7261 caagctatca tacaattatt actcaaaaat acatcatcag aaatcttgag ttttgctcct
     7321 tttctaactt tcaatactcc cccggcgttt actctaatct tttttcctaa gattaattta
     7381 gcattagatt cctgttcgac agttacattc tttccaaatt ttaaaaaata atgaaaagta
     7441 agatccttgt ttcgacacac ttttaataat atcaagcaaa tatttgcacg aagtaaacca
     7501 acaatatttt ttataatcct attcatctaa agctcctttt attttatcta aataagcatc
     7561 tataataatt tgacgagaaa aatattgctc tatatacatt ctcccttgaa gtcccatctc
     7621 ttttcgtttt tcattttcta gacctaaaaa aacttccaat atagagacta gttcctcaac
     7681 atttccccct tgaaatatat agcctgtctc tctatcttta acaatttctt tgcaacctgg
     7741 attatctgtc gtaattaaaa cacgtcctga actagcgttt tctagtaata cattgctcat
     7801 tccttcacca tacacactgg gatggataat tgcatgggaa cgggtaatat gaggtatcac
     7861 atctttttgt tgtcccaaat aataaacgat tccttttttt tctaagtcac aaattttaag
     7921 ttcataatta ctctctgtcg gttctataaa gccaataata ttaaactctg ttttgggata
     7981 tcgactctta ataatttggg cagcagccag ataagtatct ataccttttt cttttaatat
     8041 cctaccaata aaattaaaaa cgattgtttc tccttgaatt ccatttccac catttggata
     8101 ctgttgcaca ggatactttt caatgttcac tcctgaccca ggtatcagct tagagtcacc
     8161 caaaatcaag ccaagagttt ttaacatttt catattatat tcattttgaa aaaaaacaca
     8221 atttgatttc ctaaaagaaa ttctaaacag taataacacc aggcttctta cacaagaacc
     8281 cattgttaag acactaccta aacctgttac gttatttata tattttattc ctaaaattgt
     8341 tgcagctagg ctagcatata catttggttt cacggtatat gtcaagacta catccggtct
     8401 atattttctc aataatctta tataactaag aaatagacga atatctttta aagggtttat
     8461 tcctcttcta tcaatagtaa tatcttcata ctcaaattga atagacttca tcaactctat
     8521 cttatctcca taaggacatg acactagcac ttcataccca tactcaacta gtgactctat
     8581 aacttctttt cgaaaacaat agatatcatc gtcatgatta gttattaaca taattttttt
     8641 cttttgtaaa ttcatcaaaa taatcttcct aaaatataat taaccgctac tccattatcc
     8701 tttacaacta tcattttaaa aatagtaatt ttctataagt aattgtttcc aaattgtgac
     8761 actttaaaat tctatacaca tatagaactt acaaactatt tacgaccgta aactccatac
     8821 ttatcaaccg ggatatccaa tttatttaaa acaactccca ggaacagttc ccctgtttgt
     8881 tctaattgtt gtttcgcttt ttggacatca cgtttattcg cctcacctgt tgctgttatc
     8941 aagatggacg catcacactt ttgagtgata attgccgcat caataacaat tccaataggt
     9001 ggtgtatcaa caatgatata atcaaaatat ttacgcaatg tttcaatcat atcattaaaa
     9061 tttttacttt gtaacaaggc tgtagggttt ggtgatacag atcccgattg aactacaaat
     9121 aaattttcaa tatttgtatc acataaaccg tgagataaat cagctgtccc agataaaaat
     9181 tctgttagcc ctgtaatttt ttcacgagat ttaaaaaatc ctgacataac tgaatttcga
     9241 atatcgccat cgaacaaaag agttttatag cctgcacgcg caaatgacat tgctatattt
     9301 acggaaatag ttgtttttcc ttcccccgga ttaacagaag taacggaaat tacttttagt
     9361 ttatctccgc tcaactgtat atttgtacac aaggtattgt aatattcttc tgccttctta
     9421 atgaactcca gttttttttg tgctatttct aatgtcggca tctctctctc ctatttcaac
     9481 ttacccaagt ttggtacaac tcccaaaagt gtcatctgca gtgcattttc gatatcttcc
     9541 ggacgtttca cacgagtgtt caaaagttca agaagaagaa ctataacact agttccaatc
     9601 acccctgcca aaaaaccaat tagtgtattg cgtttaatat ttggcgaaga cggtgatatc
     9661 gccggtcttg cctcctccag tgttgtcaca tcagaaacac gagtaatact gataattttt
     9721 tgagcagcta cttctcttaa agagttagcg atacggcttg cctcttcagg aactcgatca
     9781 ctaactgaaa cagagacaat acgggtatca actggtactg ttactttaat tttattagcc
     9841 aaaccttttg gcatcaaatc tagtttcaaa tcagaaataa cttcctccaa aacatcctgc
     9901 gataggacaa tttcacgata gtctttaacc aagtatgctc ctgcctgcaa gtcttgattg
     9961 gttaaaccag gcttctctcc ctgattacgg ttaactagat aaatccgagt cgtactagta
    10021 aactcaggtt tgataacaaa agtactgtag gcaaaagcaa ctgaagaagt tataattgcc
    10081 actaataaaa tgaccaactt tcttttccat aaagctctga atagttgcaa tacatcgatt
    10141 tccaaagtgt tttgttcctt catattttct cctaaattaa ttgatccatt ataatttttc
    10201 tgggattatc tacaaaaagt tctttcgctt ttttcgctcc atatttctta gcaatgatat
    10261 catatgcctg ttgcatatat ggaggtctac tgtctaaatt gtgcatgtca cttgcaacta
    10321 catgaactaa atcacgttcc aaaaaatacc gagctctctt tttcatgaat ttatattttt
    10381 caccaaagaa cttaggtttt gaaacatgat aactatttat ctgagtatag caccccatat
    10441 caatcagttc acgaacacgt ttttcgttat tctctaaagc atcataacgt tcaatatgag
    10501 caattactgg cgtgattccc aacatcaaaa tattgctcaa tcccgtatga atctgacgat
    10561 aggaagtatg catgctaaac tcaatcaagg cataacgact atcattaagg gtaggaattt
    10621 cttttttttc tagcttttct agagcatcca gagtatagta tatctctgcg ccataagcaa
    10681 tgactaaatc atctgctact tcttttgcaa tttcccgaac ctgaagaaag ttttctgcta
    10741 tcttctcttc cggagtttca aacatgccct tgcgacggtg agaggtagag acaatggttc
    10801 tcaccccctg cctgtaggat tctgccaaga gagccttgct ttcctctctt gacttgggac
    10861 catcatctac atcaaagacg atgtgcgaat ggatgtctat cattttatct accctccatc
    10921 acatcctgta tagctgcttt aactacagtt aaactactat catctatttc catcacatag
    10981 aggttactgt ctggcattgc ataagaagga agatccatcc gacctgtccc ttttaaatct
    11041 tgagaattta ctttataatt ccctccactt tccaactgag tattcactaa atctatcata
    11101 gtctcaatcg gtatatttgt ttgaagagaa tcctgcaatc cttgaagaat actactatag
    11161 tttttcaaaa cctctgtaga agttaacttc tgaataattg ctacaatgac cttttgttgg
    11221 ttgcgaccac ggtcacggtc tccatcggtt agtgagtagc gttcacgtac aaaacctaaa
    11281 gcttgctcag agtctagatg gacattccct actgggaaat ggaacttccc atgtagagct
    11341 gaaaactctt gatcattatg aacatctacc cctcccaata agtcaatcat tttcaagaaa
    11401 gaagtgaagt tcaatcgcac atagtaattg atatccactc catagagatt ttctaaggtg
    11461 tgaatggacg aatcaactcc ataaatgccc gcatgggtta atttatcttt ttgattattt
    11521 ccactatctg cgattggtac ataggcatca cgtggcgttg tggtcaagag gattttcttg
    11581 gtatctcgat tgacagtcat taggatattg acatctgatc gcgacaccga actaatagga
    11641 ccataggtgt caattccact aacatagata ttgaaagact gattcttaga cgtcttagga
    11701 gcctctactt ttttagtgaa tcccttggta taaatctttt ttatcttcga tgcgtagtct
    11761 ggatactctg actcgatgat attttcaaag acactattta ggacaatggc cttagtctcc
    11821 cctgcaatca aactcttgta agctgccaag taagacgaac tctggttgac cgtcaaatcg
    11881 gtattctgac ttgacttgat atcagctagt agtttttgaa tattttcatt atcagtccca
    11941 gtcggtgctg tcacactcgt cagttgcgta acattttcga tcttactatc tgctaaaaca
    12001 gcgacactga ttgaatattc tgagtaatta gaagtcgcat ttaaacgatt ggtcagtcca
    12061 acaaactgct gtactgcaaa gagcgacact gagctgacaa ggatagagaa cagcaacaga
    12121 aaaatagtaa acttttcagc ttttttatag ataatcaaga gtagccctac caaggcaact
    12181 agtaggacta acgcagttac cactaggtta agatatctaa aagcaaggat attgtactta
    12241 aagattaaga acaataaaaa acaaattaac aataaataaa tagtcagcaa aacgatatta
    12301 acacttcgct tcactttctg tgaacgtgat tttttaaaac gtctactcat gattaacacc
    12361 tataccttga acatcataca attatatcac ttttttacgg taatgtctac acctttattt
    12421 tcactatctg catctttaag tatcttagta gacttcccgc gaaccaaaaa tatagtaaaa
    12481 tgaaataaga ataggacaaa tcaatcagga cagtcaaatc gatttctaac aatgttttag
    12541 aatcagatgt gtactattct agtttcaata taa
//
LOCUS       DAVBIC010000057        12004 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.057, whole genome shotgun sequence.
ACCESSION   DAVBIC010000057 DAVBIC010000000
VERSION     DAVBIC010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12004)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12004)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12004
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.057"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            <1..150
                     /locus_tag="VQ664_001799"
     CDS             <1..150
                     /locus_tag="VQ664_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2789913.1"
                     /translation="LSKERSKVENIFAKVKTFKMFSTTYRNHRKRFGLRMNLIAGIIN
                     HELGF"
     gene            342..2633
                     /gene="pcrA"
                     /locus_tag="VQ664_001800"
     CDS             342..2633
                     /gene="pcrA"
                     /locus_tag="VQ664_001800"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HET2789914.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQA
                     GDMYTQIVAQCYTTYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGLGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNAQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDPDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSGLPFGQFTAGAKSASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
     gene            2676..3356
                     /gene="radC"
                     /locus_tag="VQ664_001801"
     CDS             2676..3356
                     /gene="radC"
                     /locus_tag="VQ664_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HET2789915.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(3353..4042)
                     /locus_tag="VQ664_001802"
     CDS             complement(3353..4042)
                     /locus_tag="VQ664_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HET2789916.1"
                     /translation="MKKPVIGITGNEKAHPDDDIMMSYAAKGFVEGVKDAGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGEPKTIDSDDYNLQRDIFELALIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(4060..4701)
                     /locus_tag="VQ664_001803"
     CDS             complement(4060..4701)
                     /locus_tag="VQ664_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HET2789917.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            complement(4784..4999)
                     /locus_tag="VQ664_001804"
     CDS             complement(4784..4999)
                     /locus_tag="VQ664_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HET2789918.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGQKVYQGLVGDLYRFLSHADFLHQN"
     gene            complement(5007..5354)
                     /locus_tag="VQ664_001805"
     CDS             complement(5007..5354)
                     /locus_tag="VQ664_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HET2789919.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKELTGAKINITDKFSLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            complement(5359..6474)
                     /locus_tag="VQ664_001806"
     CDS             complement(5359..6474)
                     /locus_tag="VQ664_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HET2789920.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFANNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLEAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            complement(6484..7443)
                     /locus_tag="VQ664_001807"
     CDS             complement(6484..7443)
                     /locus_tag="VQ664_001807"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HET2789921.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            complement(7556..8125)
                     /locus_tag="VQ664_001808"
     CDS             complement(7556..8125)
                     /locus_tag="VQ664_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HET2789922.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTPDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAEDYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDITDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            8253..8924
                     /locus_tag="VQ664_001809"
     CDS             8253..8924
                     /locus_tag="VQ664_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HET2789923.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGAKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            8908..9726
                     /locus_tag="VQ664_001810"
     CDS             8908..9726
                     /locus_tag="VQ664_001810"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HET2789924.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLDKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIDHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            9723..10619
                     /locus_tag="VQ664_001811"
     CDS             9723..10619
                     /locus_tag="VQ664_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HET2789925.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIDIPAEEGFETLEAIEHPLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            10663..11637
                     /gene="pta"
                     /locus_tag="VQ664_001812"
     CDS             10663..11637
                     /gene="pta"
                     /locus_tag="VQ664_001812"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HET2789926.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
BASE COUNT         3498 a         2295 c         2583 g         3628 t
ORIGIN      
        1 ctatccaagg agagaagcaa ggttgagaac atctttgcca aagtaaaaac gtttaaaatg
       61 ttttcaacaa cctatcgaaa tcatcgtaaa cgcttcggat tacgaatgaa tttgattgct
      121 ggcattatca atcatgaact aggattctag ttttgcagga agtctattga ggtattgagc
      181 tagtttatga aaaaattggg tgaaaaagtc gagtgtttta gaaacccaca gtgtagtatt
      241 ctagtttcaa tccactatat tttgctactc cccgtaaagt ttctattttc cctgatttct
      301 gatataatag aaatattgac ttcaagagta aggaagagaa gatgaacgca ttattaaatg
      361 gaatgaatga ccgtcaggct gaggcggtgc aaacgacaga aggtcccttg ctaatcatgg
      421 caggagctgg ttctggaaag actcgtgttt taacccaccg tatcgcttat ttgattgatg
      481 aaaagctggt caatccttgg aatatcttgg ccattacctt taccaacaag gctgcgcgtg
      541 agatgaaaga gcgtgcttat agcctcaatc cagctactca ggactgtctg attgcgacct
      601 tccactccat gtgtgtgcgt attttgcgtc gcgatgcgga ccatattggc tacaatcgta
      661 attttacaat tgtggatcct ggtgaacagc gaacgctcat gaaacgtatt ctcaaacagt
      721 tgaacttgga tcctaaaaaa tggaatgaac gaactatttt ggggaccatt tccaatgcta
      781 agaatgattt gattgatgat gttgcttatg ctgctcaagc tggcgatatg tatacgcaaa
      841 ttgtggccca gtgttataca acctatcaaa aagaacttcg tcagtctgaa tccgttgact
      901 ttgatgattt gattatgctg accttgcgtc tctttgatca aaatcctgat gttttgacct
      961 actaccagca aaaattccaa tacatccacg ttgatgagta ccaagatacc aaccacgctc
     1021 agtaccaatt ggtcaaactc ttggcttccc gttttaaaaa tatctgtgtg gttggggatg
     1081 cggaccagtc tatctacggt tggcgtggtg ctgatatgca gaatatcttg gactttgaaa
     1141 aggattaccc caaagctaag gttgttttgt tggaggaaaa ttaccgctca accaaaacca
     1201 ttctccaagc ggccaacgag gttattaaaa ataataaaaa tcgccgtcct aaaaatctct
     1261 ggactcaaaa cgctgatggg gagcaaatcg tttactatcg tgctgatgat gagctggatg
     1321 aggctgtatt tgtagccaga accatcgatg aacttagtcg cagtcaaaac ttccttcata
     1381 aggattttgc agttctctat cggactaatg cccagtcccg tacaattgag gaagccctgc
     1441 tcaagtctaa cattccttat accatggttg gcggaaccaa attctacagc cgtaaggaaa
     1501 ttcgcgatat tattgcttat ctcaacctta ttgctaattt gagtgacaac attagttttg
     1561 agcgtattat caacgagcct aaacgtggaa ttggtctagg tacagttgag aaaatccgtg
     1621 attttgcaaa tttgcaaaat atgtctatgc tggatgcttc tgctaatatt atgttgtctg
     1681 gtatcaaggg taaggcagcc caatctatct gggattttgc caatatgatg cttgatttgc
     1741 gggagcagct agaccactta agcattacag agttggttga gtccgtccta gaaaaaacag
     1801 gttatgtcga tattcttaac gcccaagcga ctctagaaag caaggcaagg gttgaaaata
     1861 tcgaagagtt tctttctgtt acgaagaact ttgatgacac cactgatgtg acagaagagg
     1921 aaactggtct ggacaaactg agtcgtttct taaatgactt ggctttgatt gccgacacag
     1981 attcaggtag tcaggagaca tcagaagtga ccttgatgac cctgcatgct gccaaaggtc
     2041 tcgaatttcc agttgtcttt ttgattggga tggaagaaaa tgtctttcca cttagtcgtg
     2101 cgactgaaga tccagatgaa ttagaagaag agcgccgtct agcctatgta ggtatcacgc
     2161 gtgcagagaa aattctctat ctgaccaatg ccaactcacg cttgcttttt ggtcgtacca
     2221 attataaccg tccgactcgt tttattaacg aaatcagttc agacttgctt gagtatcaag
     2281 gtctggctcg tcctgcaaat acaagcttta aggcatcata tagcagtggt agtatttcct
     2341 ttggtcaagg tatgagtttg gctcaggctc ttcaagaccg taaacgcggt gctgccccaa
     2401 aatcgatcca gtcaagcggt cttccatttg gtcaatttac agctggcgca aaatcagcat
     2461 ctagcgaggc aaattggtcc attggtgaca ttgctctcca caagaaatgg ggagagggaa
     2521 ctgttctgga agtttcaggt agcggtgcta ggcaggaatt gaaaatcaat ttcccagaag
     2581 taggtttgaa aaaactttta gccagtgtgg ctccaattga gaaaaaaatc taattttcca
     2641 tccttctcac gaataataaa gtgaggagga tttttatgta cagtatttca ttccaagaag
     2701 attcactatt accaagagaa aggctggcca aggaaggagt tgaagcgctt agtaaccaag
     2761 agttgctagc tattttactc aggacaggaa cacgtcaagc tagcgttttt gaaattgccc
     2821 aaaaagtctt gaacaatctt tcaagcctaa cggatttgaa aaaaatgacc ctgcaggaat
     2881 tgcagagttt gtctggtatt gggcgtgtta aggccataga attacaagct atgattgaac
     2941 tggggcatcg tattcacaaa cacgagactc ttgaaatgga aagtattctc agcagtcaaa
     3001 agttggccaa gaagatgcag caggaattag gggataaaaa acaagagcac ctggtggcac
     3061 tctatctcaa tactcaaaat caaatcatcc atcagcagac catttttatc ggttctgtaa
     3121 ctcgtagtat cgctgaaccg cgagagattc ttcactatgc aatcaagcat atggcgactt
     3181 ctcttatctt ggtccacaat catccttcag gagcggtagc gcctagccaa aatgatgatc
     3241 atgtcactaa acttgttaaa gaagcctgcg aattgatggg gattgttctc ttggaccatt
     3301 tgattgtctc tcattctaat tactttagtt atcgtgaaaa gacagattta atctaaagtt
     3361 cattaacgac atagtcaaag agttttttat ctttgggacg attttcaaaa agaagttctg
     3421 gatgccattg gacaccgaga aaggcgacat catccgtact catgacagcc tcaatgatac
     3481 catctttagg atcatgagcc acaactttta aatttggtgc taagtccttg atgctctggt
     3541 ggtggaagga gttgatatga gagatttctc catagatttc ttggagaacg gtatctggtt
     3601 ctgttaccaa gcgttgagtt gtgtactcaa cagaagaatc ctgccaatgg tcttcgatat
     3661 cttggtacaa agttccaccc atggcaacgt taaagagttg ggtaccacgg cagacagaga
     3721 aaatgggctt tttctgttta atagcttcct tgatgagggc cagttcgaag atatctcttt
     3781 gaaggttata gtcatcgcta tcaatggttt tgggttcgcc ataaaatttt ggatcgacat
     3841 tttgcccacc tgtcaagatg agcttgtcaa tcaaactgat atagtggcag gccatttctt
     3901 gatcaccaat cggtaggatg atgggaatcc ctccagcatc tttaacgcct tcaacaaagc
     3961 cttttgctgc gtagctcatc atgatgtcat catctggatg agctttttcg tttcctgtaa
     4021 tcccaataac tggttttttc ataaaatgat tttcgctttc taatcctctt ttcgcatgaa
     4081 gtagaggagg gtttggagtt cacttgtcaa atcgacatac tgaacgacca cgtcttttgg
     4141 taaatgcaga tggactggtg aaaaactgag aattcctttc acaccagcat caaccaagag
     4201 attagcaacc tcttgtgact tgacgctggg aacagttagg atagcagtct tcacatcagc
     4261 atccttgatt ttatccttga tctgagaaat cccgtaaatg ggaatcccgt caggagtttg
     4321 ggtaccgact tcaggatggt cgtctaggtc aaaggccatg ataatcttca tcttgttacg
     4381 ttcgtggaag cggtagtgga gaagggcatg gcccatattt ccaataccaa ccagcatgac
     4441 attggtaata gagttgtcat tgagcaaatc ggcaaaaaat gtcattagtt ttttgacatc
     4501 atagccaaaa ccacgacgac caagttcacc aaaataggaa aaatcacgac gtacggtcgc
     4561 tgaatcaata ccgatagcct ctgcaatttg cttagagttg gcacgttcaa tcttttctgc
     4621 atgaaatctc ttaaaaattc gatagtagag agagagtctt tttgctgtag cttttggaat
     4681 agcaaactgt ttatctttca caaaatcaca acctttctat tcttctattt tatagaaaca
     4741 ttgtgaaaaa atcaacaaaa ataagaaaaa actaagaaaa atcttagttt tgatgtaaaa
     4801 aatctgcatg agatagaaaa cggtagaggt ctccgaccag accctgataa actttttggc
     4861 ccctaaaagt cagagaagtc acataaagtg tatctggtaa ggttacacat cctgacaaag
     4921 tcaacatgag agcctcatga tcctcatact tgagagtacg ctctacatga tagcagtcct
     4981 tataggtcag ttcaaacatt ttggctctat ctttccgatt ttgtaaagac accacgttct
     5041 accaagctat ccatgaggaa gtagaatttt tcctgatgaa tatggtggtc ttctgatttg
     5101 aaaatatcaa ctagacgaag gctaaacttg tcagtgatat tgattttagc ccctgtaagt
     5161 tccttgttaa tgatgatttt gagttggaag ccttcaccgc tgtttggcac tttttccaaa
     5221 aggcgagtca gttcatagtt accaacctta gtttcaaaaa aggtgttatc tttgagggtg
     5281 aattttttaa cagaagggct aagagtgtaa tcgtaacgac aattttttaa ctgaatgatt
     5341 ttttcaaatg ccatatggct aacctccgat aatttctttt aaggtttttg cgagggtttg
     5401 taggtcttca acggtatttt gtggcgacaa actgatgcga agggattcct tcaagcgttc
     5461 tgaatttgcg ccatacatgg cttcaagaac atggctggat tggacaacgc ctgcagtaca
     5521 ggctgagcca gtagagattg aaattccagc taaatctagc cgaaggagta agaggtcatt
     5581 tttctgacca ggaaatccaa tattgagaac ataagggaga tgatgttttc ctctattcaa
     5641 gtaatactga atgccctcca gctctgccag aaaggcggtt tctagatttt gtacatgttg
     5701 aaaatgttct tcttgttttt ctaggtcttc ttttagggct gcaaccatgc ctacgatagc
     5761 aggcagattt tcagttcctg cacgtttttt ctgttcctgg tctccgccat gtagatagga
     5821 atcaaagtcc atgctagatg cgtagagaaa accgattccc ttaggaccat ggaatttgtg
     5881 ggcagaagca gtgagaaaat caatgcccaa ttcttctgaa tgaattggga ttttaccaat
     5941 agcctgaact gcatcaacat gataggcagc agggtgttgc ttgagtattt ggccaatttc
     6001 agcgatgggc agtaggtttc ctgtctcatt attggcaaac atggtagaaa ccaaaatcgt
     6061 atcgtcacgt aaagcctttt gaatttgctg ggctgtgatt tcttgatttt ctggctggat
     6121 aatggttgct tcaaacccaa agtgttgaac caagtaatca attgtttcaa ggacagcatg
     6181 gtgctcgatg gcagttgtga tgatatgttt tccttgttct tggtgacgaa gacagtagcc
     6241 aatgatggta gtattattgc cttcagtccc accagaagtg aaaaagatat gttgaggttt
     6301 tgtccttagt aactgggcta gttcctgacg ggcttctcgc aagagtttgc cagcttgacg
     6361 accatgacca tgaatactag aaggatttcc gtgggtttct tgcataacct tggtcatagc
     6421 tgaaatagca actgctgaca taggagtcgt tgcagcattg tccaaataaa tcaaagaatc
     6481 accttatttc tttttattgt aggcaaagag tgggctgact ggttttcttt cgtgaatacg
     6541 gacgatagca tcaccaatta actcactagc agtgatgtag catacatttt taggagtttt
     6601 ttcttttgtt gctactgaat cagtcacaag aatttcttta atattagtat tgtcaagaag
     6661 ctcagcagct ccctcgacga agagaccgtg gctagaaaca gcataaattt ctgtagctcc
     6721 ttcacgttca acgattttag aagcttcaga gaaggtacgt cctgtattta aaatatcatc
     6781 aatcaagata gctttcttac cttcaacatc accaataata taaccttcgt tacgagttgc
     6841 atcgtcttga gggtagtcga taatggcgat aggagcatca agatattcag ccaggctacg
     6901 cgcacgtttg acacctgaat ttttagggct aacgacaaca acatctgaac caagcaatcc
     6961 tttatcgcag taatgttttg cgaatagggg aacagtgaaa agattatcca ctggaatatc
     7021 aaagaaacct tgaacctgaa cggcatgcaa atcaagagtc aggatacgat caactccagc
     7081 cttaaccagc atattggcaa ctagttttgc tgtaagtggc tcacgaggac aagcaatgcg
     7141 gtcttgacgt gcatagccaa aatatggaag gacaacgttg atactgtggg cacttgcacg
     7201 cacacaagca tcgaccatga ttaacaattc cattaggtgg ttgttgacag ggaaacttgt
     7261 tgattggatg atgtaaacat cataaccacg gacactttct tcgatattta cttggatttc
     7321 tccgtctgaa aattgacgtg atgatagttt tccaagtggg acaccaacag cttgggcaat
     7381 tttttgtgca atctcttggt tagagttgag tgcgaaaagt ttcatgtttt ttctatctga
     7441 cattatagac cgtcctctgt aaactttata aatcctagtt atatttacct tacatatatg
     7501 aactgggatt tgtgtatttt tatcttttct attttaccaa aaaatggaga ttatttcagc
     7561 tatttttcat acttttgaca aatcgaacca attttgaagg agctttttgg taggaaatct
     7621 gatttttctc taaaaattgt cggaaatcct gtttgccttg ctcatgattt tccacttcaa
     7681 gctccaattc gtaatctgtt atatcaaagt atcggctctg atccagtgcc atgagaccaa
     7741 tagctgtttt catttcatag cgaagcgttg ttagacaacc aagaacctgc cagttcttac
     7801 tttggatacc atgtttcgcc aattcatcca gtactagtcc ttgaggaagt tcttccttac
     7861 tcagatagtc ctcagcatct tttagttgca atttttggtt gtattccatg tttccaacac
     7921 tctgcgggac tttgagtgtc aactcagccc agtcttcaaa ggttcgaatg cgcatagcga
     7981 ctttcttttc tcgcagttca aaatcaggcg tgtcgatgta gtaatttgtt tgaagaacag
     8041 gagtgacacc tgtgaactgg tcttttagac gattgtattc atcttttttc aatagtgttt
     8101 tcaattcaat ttctaaatgt ttcatttttc ttaccttttt ttatcgttga aagcggattt
     8161 atggtataat aagcattgta tttattgtat atgaatctgg agaaaaaatc aaagatattt
     8221 ttgacggata atatgagaac aagggagaat atatgacctt agaatgggaa gaatttctag
     8281 atccttacat tcaagctgtt ggtgagttaa agattaaact tcgtggtatt cgtaagcaat
     8341 atcgtaagca aaataagcat tctccaattg agtttgtgac cggtcgagtc aagccaattg
     8401 agagcatcaa agaaaaaatg gctcgtcgtg gcattactta tgcgaccttg gaacacgatt
     8461 tgcaggatat tgctggctta cgtgtgatgg ttcagtttgt agatgacgtc aaggaagtag
     8521 tggatatttt gcacaagcgt caggatatgc gaatcataca ggagcgagat tacattactc
     8581 atagaaaagc atcaggctat cgttcctatc atgtggtagt agaatatacg gttgatacca
     8641 tcaatggagc taagactatt ttggcagaaa ttcaaattcg tactttggcc atgaatttct
     8701 gggcaacgat agaacattct ctcaactaca agtaccaagg ggatttccca gatgagatta
     8761 agaagcgact ggaaattaca gctagaatcg cccatcagtt ggatgaagaa atgggtgaaa
     8821 ttcgtgatga tatccaagaa gcccaggcac tttttgatcc tttgagtaga aaattaaatg
     8881 acggtgtagg aaacagtgac gatacagatg aagaatacag gtaaacgaat tgatctgata
     8941 gccaatagaa aaccgcagag tcaaagggtt ttgtatgaat tgcgagatcg tttgaagaga
     9001 aatcagttta tactcaatga taccaatccg gatattgtca tttccattgg cggggatggt
     9061 atgctcttgt cggcctttca taagtacgaa aatcagcttg acaaggtccg ctttatcggt
     9121 cttcatactg gacatttggg cttctataca gattatcgtg attttgagtt ggacaagcta
     9181 gtgactaatt tgcagctaga tactggggca agggtttctt accctgttct gaatgtgaag
     9241 gtctttcttg aaaatggtga agttaagatt ttcagagcac tcaacgaagc cagcatccgc
     9301 aggtctgatc gaaccatggt ggcagatatt gtaataaatg gtgttccctt tgaacgtttt
     9361 cgtggagacg ggctaacagt ttcgacaccg actggtagta ctgcctataa caagtctctt
     9421 ggcggtgctg ttttacaccc taccattgaa gctttgcaat taacggaaat tgccagcctt
     9481 aataatcgtg tttatcgaac actgggctct tccattattg tgcctaagaa ggataagatt
     9541 gaacttattc caacaagaaa cgattatcat actatttcgg ttgacaatag cgtttattct
     9601 ttccgtaata ttgagcgtat tgagtatcaa atcgaccatc ataagattca ctttgtcgcg
     9661 actcctagcc ataccagttt ctggaaccgt gttaaggatg cctttatcgg tgaggtggat
     9721 gaatgaggtt tgaatttatc gcagatgaac atgtcaaggt taagaccttt ttaaaaaagc
     9781 acgaggtttc taagggattg ctggctaaga ttaagtttcg aggtggagct attctggtca
     9841 ataatcaacc gcaaaatgca acgtatctat tggacgttgg agactacgtt accattgaca
     9901 ttcccgctga ggaaggcttt gaaaccttgg aggctattga gcatccatta gatattctct
     9961 atgaggatga ccactttcta gtcttgaata aaccctatgg agtggcttct attcctagtg
    10021 tcaatcactc taacaccatt gccaatttta tcaagggtta ctatgtcaag caaaattatg
    10081 aaaatcagca ggttcacatt gttaccagac tagataggga cacttctggc ttgatgctct
    10141 ttgccaagca cggttatgcc catgcacgat tagacaagca gttgcagaag aaatctatcg
    10201 agaaacgcta ctttgctttg gttaagggag atggacattt ggagccagaa ggggaaatta
    10261 ttgctccgat tgcgcgtgat gaagattcca ttattaccag acgagtggct aaaggcggaa
    10321 agtatgccca tacttcatac aagattgtag cttcttatgg aaatattcac ttggtctata
    10381 ttcacctgca cactggtcga acccatcaaa tccgagtcca tttttctcat atcggttttc
    10441 ctttgctggg agatgatttg tatggtggta gtctggaaga tggtattcaa cgtcaggctc
    10501 tgcattgcca ttacctatcc ttttatcatc catttttaga gcaagacttg cagttagaaa
    10561 gtcccttgcc ggatgatttc agtaacctta ttacccagtt atcaactaat actctataaa
    10621 aactgtctca gagtataatt attatcttaa aggagaaaac tcatggaagt ttttgaaagt
    10681 ctcaaagcca accttgttgg taaaaatgct cgtatcgttc tccctgaagg ggaagagcct
    10741 cgtattcttc aagcaacaaa acgcttagta aaagaaacag aagtgattcc tgttttgctt
    10801 ggaaatcctg aaaaaattaa aatttatctt gaaattgaag gaatcatgga tggttatgag
    10861 gtcatcgacc ctcaacatta tcctcaattt gaagaaatgg tttctgcctt ggtggagcgt
    10921 cgcaagggca aaatgactga agaagatgta cgcaaggttt tggttgaaga tgtcaactac
    10981 tttggtgtga tgttggttta cttgggcttg gttgatggaa tggtgtcagg agcgattcac
    11041 tcaacagctt caacagttcg tccagctcta caaatcatca aaactcgtcc aaatgtaact
    11101 cgtacttcag gagccttcct catggttcgt ggtacggaac gttacctatt tggagactgt
    11161 gccattaaca tcaatccaga tgcagaagcc ttggctgaaa ttgccatcaa ctcagcaatc
    11221 acagctaaga tgtttggcat cgaacctaaa attgccatgt tgagctattc tactaaaggt
    11281 tcagggtttg gtgaaagcgt tgataaggtc gttgaagcaa ctaaaattgc tcacgacttg
    11341 cgtcctgacc ttgaaatcga tggtgagttg caatttgatg cagcctttgt tcctgaaact
    11401 gcagctctga aagctcctgg aagtacggta gctggtcaag caaatgtctt catcttccca
    11461 ggtatcgagg ccggaaatat cggttacaag atggctgaac gcctgggtgg ctttgcggct
    11521 gtaggacctg ttttgcaagg tttaaacaag ccagttaatg atctttctcg tggatgtaat
    11581 gcagatgatg tttacaagtt gaccctcatc acagcagctc aagcagttca tcaatagtga
    11641 aaactataaa gcgatatact atgctatact gtagttatga aactatgtac gaaaagcact
    11701 gccattaatt cctgagaact aaattactga ttggtgtcaa aaaggaaaac ttccaagcga
    11761 tgatatcctg tctatacacg acctatagaa atctgtaata tgtatgtccg taaaacgata
    11821 atttcccttt ttgattttaa atgagtatga aaagagaatt ttttcatgag aaaacgcata
    11881 atattaagtg tcttgacacc tgctattatg cgttttctgg ctctttgtca actgtagtgg
    11941 gttgaagaaa agctaagctc gagaaaggac aaattttgtc ctttcttttt tgatattcag
    12001 agcg
//
LOCUS       DAVBIC010000058        11905 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.058, whole genome shotgun sequence.
ACCESSION   DAVBIC010000058 DAVBIC010000000
VERSION     DAVBIC010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11905)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11905)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11905
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.058"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            51..497
                     /gene="argR"
                     /locus_tag="VQ664_001813"
     CDS             51..497
                     /gene="argR"
                     /locus_tag="VQ664_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HET2789927.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDEWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            548..3082
                     /gene="mutS"
                     /locus_tag="VQ664_001814"
     CDS             548..3082
                     /gene="mutS"
                     /locus_tag="VQ664_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HET2789928.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKLDSQNNFLVAIDREGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSCQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPALAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKSA
                     NLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLITGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTENPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            3229..4923
                     /gene="patA"
                     /locus_tag="VQ664_001815"
     CDS             3229..4923
                     /gene="patA"
                     /locus_tag="VQ664_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatA"
                     /protein_id="HET2789929.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLGALLTG
                     KYEAIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SDELLGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDVPDEELVGSLSFENVTF
                     TYPMDKEPMLKDVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQEGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
     gene            complement(5253..5522)
                     /locus_tag="VQ664_001816"
                     /pseudo
     CDS             complement(5253..5522)
                     /locus_tag="VQ664_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770457.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            5714..7480
                     /gene="patB"
                     /locus_tag="VQ664_001817"
     CDS             5714..7480
                     /gene="patB"
                     /locus_tag="VQ664_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HET2789930.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTHVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMSLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     SQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            7619..8308
                     /locus_tag="VQ664_001818"
     CDS             7619..8308
                     /locus_tag="VQ664_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HET2789931.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLDEL"
     gene            8312..8491
                     /locus_tag="VQ664_001819"
     CDS             8312..8491
                     /locus_tag="VQ664_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789932.1"
                     /translation="MEHLVVLSFIFSKFLECGILRKRLNSDKNWRNSTKKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            8478..9827
                     /locus_tag="VQ664_001820"
     CDS             8478..9827
                     /locus_tag="VQ664_001820"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HET2789933.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWGTFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAAVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            9951..11411
                     /locus_tag="VQ664_001821"
     CDS             9951..11411
                     /locus_tag="VQ664_001821"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HET2789934.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVVIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDKFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENMLKEISK"
     gene            11425..11859
                     /locus_tag="VQ664_001822"
     CDS             11425..11859
                     /locus_tag="VQ664_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HET2789935.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAEDGQIFTGF
                     CMEGTCGVFHLCAERAALFNTYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVAELIPYWWGEERASKFNER"
BASE COUNT         3528 a         2289 c         2715 g         3373 t
ORIGIN      
        1 gtataatatg gttataaata tagttataaa tatgcacgca agaggatttt atgagaaaaa
       61 gagatcgtca tcagttaata aaaaaaatga ttactgagga gaaattaagt acacaaaaag
      121 aaattcaaga tcggttggag gcgcacaatg tttgtgtgac gcagacaacc ttgtctcgtg
      181 atttgcgcga aatcggcttg accaaggtca agaaaaatga tatggtgtat tatgtactag
      241 taaatgagac agaaaagatt gatttggtgg aatttttgtc tcatcattta gaaggtgttg
      301 caagagcaga gtttaccttg gtgcttcata ccaaattggg agaagcctct gttttggcaa
      361 atattgtaga tgtaaataag gatgaatgga ttttaggaac agttgctggt gccaatacct
      421 tattggttat ttgtcgagat cagcacgttg ccaaactcat ggaagatcgt ttgctagatt
      481 tgatgaaaga taagtaaggt cttgggagtt gctctcaaga cttatttttg aaaaggagag
      541 acagaaaatg gcgatagaaa agctatcacc cggcatgcaa cagtatgtgg atattaaaaa
      601 gcaatatcca gatgcttttt tgctctttcg gatgggtgat ttttatgaat tattttatga
      661 ggatgcggtc aatgctgcgc agattctgga aatttcctta acgagtcgca acaagaatgc
      721 cgacaatccg atccctatgg cgggtgttcc ctatcattct gcccaacagt atatcgatgt
      781 cttgattgag cagggttata aggtggctat cgcagagcag atggaagatc ctaaacaagc
      841 agttggggtt gttaaacgag aggttgttca ggtcattacg ccagggacag tggtcgatag
      901 cagtaagctg gacagtcaga ataatttttt ggttgccata gaccgcgaag gcaatcaatt
      961 tggcctagct tatatggatt tggtgacggg tgacttttat gtgacaggtc ttttggattt
     1021 cacgctggtt tgtggggaaa tccgtaacct caaggctcga gaagtggtgt tgggttatga
     1081 cttgtctgag gaagaagaac aaatcctcag ctgccagatg aatctggtac tctcttatga
     1141 aaaagaaagc tttgaagacc ttcatttatt ggatttgcga ttggcaacgg tggagcaaac
     1201 ggcatctagt aagctgctcc agtatgttca tcggactcag atgagggaat tgaaccacct
     1261 caaacctgtt atccgctacg aaattaagga tttcttgcag atggattatg cgaccaaggc
     1321 tagtctggat ttggttgaga atgctcgctc aggtaagaaa caaggcagtc ttttctggct
     1381 tttggatgaa accaaaacgg ctatggggat gcgtctcttg cgttcttgga ttcatcgccc
     1441 cttgattgat aaggaacgaa tcgtccaacg tcaagaagta gtgcaggtct ttctcgacca
     1501 tttctttgag cgtagtgact tgacagacag tctcaagggt gtttatgaca ttgagcgctt
     1561 ggctagtcgt gtttcttttg gcaaaaccaa tccaaaggat ctcttgcagt tggcgactac
     1621 cttgtctagt gtgccacgga ttcgtgcgat tttagaaggg atggagcaac ctgctctagc
     1681 ctatctcatc gcacaactgg atgcaatccc tgagttggag agtttgatta gcgcagcgat
     1741 tgctcctgaa gctcctcatg tgattacaga tgggggaatt atccggactg gatttgatga
     1801 gactttagac aagtatcgtt gcgttctcag agaagggact agctggattg ctgagattga
     1861 ggctaaggag cgagaaaact ctggtatcag cacgctcaag attgactaca ataaaaagga
     1921 tggctactat tttcatgtga ccaattcgca actgggaaat gtgccagccc actttttccg
     1981 caaggcgacg ctgaaaaact cagaacgctt tggaaccgaa gaattagccc gtatcgaggg
     2041 agatatgctt gaggcgcgtg agaagtcagc caacctcgaa tacgaaatat ttatgcgcat
     2101 tcgtgaagag gtcggcaagt acatccagcg tttacaagct ttagcccaag gaattgcgac
     2161 ggttgatgtc ttacagagtc tggcggttgt ggctgaaacc cagcatttga ttcgacctga
     2221 gtttggtgac gattcacaaa ttgatatccg gaaagggcgc catgctgtcg ttgaaaaggt
     2281 tatgggggct cagacctata ttccaaatac gattcagatg gcagaagata ccagtattca
     2341 actgattaca gggccaaaca tgagtgggaa gtctacctat atgcgtcagt tagccatgac
     2401 ggcggttatg gcccagctgg gttcctatgt tcctgctgaa agcgcccatt taccgatttt
     2461 tgatgcgatt tttacccgta tcggagcagc agatgacttg gtttcgggtc agtcaacctt
     2521 tatggtggag atgatggagg ccaataatgc catttcgcat gcgaccaaga actctctcat
     2581 tctctttgat gaattgggac gtggaactgc aacttatgac gggatggctc ttgctcagtc
     2641 catcatcgaa tatatccatg agcacatcgg agctaagacc ctctttgcga cccactacca
     2701 tgagttgact agtctggagt ctagtttaca acacttggtc aatgtccacg tggcaacttt
     2761 ggagcaggat gggcaggtca ccttccttca caagattgaa ccgggaccag ctgataaatc
     2821 ctacggtatc catgttgcca agattgctgg cttgccagca gaccttttag caagggcgga
     2881 taagattttg actcagctag agaatcaagg aacagagaat cctcctccca tgagacaaac
     2941 tagtgctgtc actgaacaga tttcactctt tgatagggca gaagagcatc ctatcctagc
     3001 agaattagct aaactggatg tgtataatat gacacctatg caggttatga atgtcttagt
     3061 agagttaaaa cagaaactat aaaaccaaga ctcactagtt aatctagctg tagcaaggag
     3121 acttctttga caattctcca cttttttgct agaatgacat cacacaaaca gaatgaaaag
     3181 gagctgacgc attgtcgctc ccttttgtct attttttaag gagaaagtat gctgattcag
     3241 aaaataaaaa cctacaagtg gcaggccctg gcttcgctcc tgatgacagg cttgatggtt
     3301 gctagttcac ttctgcaacc gcgttatctg caggaagtct taggcgccct ccttactggg
     3361 aaatatgaag ctatttatag tatcggggct tggttgattg gtgtggccgt agtcggtcta
     3421 gttgctggtg gactcaatgt tgtcctcgca gcctatattg cccaaggagt ttcatccgac
     3481 cttcgggagg atgccttccg taaaattcaa accttttctt atgctgatat tgaacaattt
     3541 aatgcgggaa atctagtcgt tcgaatgaca aatgatatca accagattca gaacgttgtc
     3601 atgatgacct tccagattct tttcagactt cccctcttgt tcatcggttc gtttatccta
     3661 gcggttcaaa ccttaccttc tctgtggtgg gtgattgttc tcatggtagt cttgattttt
     3721 ggtttgactg ctgtcatgat gggaatgatg gggcctcgtt ttgccaagtt tcaaaccctt
     3781 cttgagcgca tcaatgccat tgccaaggaa aatttacgtg gcgttcgtgt ggtcaagtcc
     3841 tttgtccaag aaaaagagca atttgctaag tttacagagg tctcagacga gcttcttggt
     3901 caaaaccttt acattggtta tgccttttca gtagtggaac cctttatgat gttggttggt
     3961 tacggggcgg tcttcctctc tatttggctg gtcgcgggaa tggttcagtc ggatccgtct
     4021 gttgttggtt ccatcgcttc ttttgttaat tacctaagcc agattatctt taccattgtt
     4081 atggttggat ttttgggaaa ttctgtcagc cgtgccatga tttccatgcg tcgtattcga
     4141 gaaattcttg acgcagagcc agctatgacc ttcaaggatg tcccagatga agagttggtt
     4201 ggaagcctta gctttgaaaa tgtgaccttt acctatccaa tggacaagga accgatgctg
     4261 aaagatgtga gctttactat tgaacctggt caaatggttg gtgtagttgg agcgactggt
     4321 gcaggaaagt caaccttggc tcaattgatt ccacgtctct ttgatccaca ggaaggggct
     4381 atcaaaatcg gaggtaagga tattcgagaa gtgagtgaag gaaccctgcg taaaacagtt
     4441 tccatcgttc tccaacgtgc cattcttttt agtggaacga ttgcagataa cttgagacag
     4501 gggaagggaa atgctactct atttgaaatg gagcgcgcag ccaatattgc ccaggctagt
     4561 gaattcattc atcgtatgga gaaaaccttt gaaagtccag ttgaagaacg gggaaccaat
     4621 ttctctggtg gacaaaaaca aaggatgtcg attgcgcgtg ggattgtcag caatccacgt
     4681 attctgattt ttgatgattc gacctcagcc ttggatgcca aatcagagcg cttggtgcaa
     4741 gaagctttga ataaggactt gaaggggacg acaaccatta ttattgctca aaaaattagc
     4801 tcggttgtcc atgcagacaa gatcttggtt ctaaatcaag gacgattgat tggtcaaggc
     4861 acgcatgcag acttggttgc caacaatgcc gtttaccgtg aaatctatga aacacagaaa
     4921 tgaaagacaa actataagaa aagtcaatag ttttatctaa actatttctt atttcaattt
     4981 gatgatttgg cgatgatttt agagcacggc aaaaagccct tgaaaaagtc cattttttca
     5041 aaggtaatcc tgtgttgatt tcagaaatta catcactttt tgttcgtcaa atggcagctc
     5101 ttttttagga tataaaacag ggttcggata agtttttttg caaggtggat gatggctaca
     5161 ttgtaatgtt ttccttgtta taacttagtc ttaagatagg ccttaaaagc aggtgaaaag
     5221 tgagggcatg ctttggcagc ttgtatgagt acctaccgca gatgagggga accccgtttg
     5281 accattcttc cagctaaatc aatctgacct gactgataaa tagaagaatc cagtccagcg
     5341 aaagcttgta attgagcagg attatcaaag gcatgaatat ttcgaatctc ggctaaaatg
     5401 accgccccta aacgattccc aatcccagta accgtcgtga tgaccgagtt gaactcagcc
     5461 atcaagtcat tgacacattt ttccgccttg tcaatgagcc tcttgtaatg tttgatgatt
     5521 tcattacacg agataaaacg tctatgcgtt atcaaactca ttaccaatta aaacaaaaag
     5581 ctgtggttag atcctttcgg aaatcgtcaa gcgattggag gaaatgaact aatccacagc
     5641 ggcttattcc aagtatacca cttgggcttt ggcagtagct aactgcgcta aatataatat
     5701 aaggaggagt aaaatgaaga cagttcaatt tttttggcat tattttaagg tctacaagtt
     5761 ctcatttgta gttgtcatcc tgatgattgt tctggcgact tttgcccaag ccctctttcc
     5821 agtcttttct ggacaagcgg tgacgcagct agccaattta gttcaagctt atcaaaatgg
     5881 caatccagaa cttgtatggc aaagcctatc aggaatcatg gtcaatcttg gcctgctggt
     5941 tttggttcta tttatctcta gtgtaatata catgtgtctc atgacgcacg tgattgcaga
     6001 atcgaccaac gagatgcgca aaggcctctt tggtaagctt gctcagttga cggtttcttt
     6061 ctttgaccgt cgacaagatg gcgatatctt gtctcatttt accagtgatt tggataatat
     6121 cctccaagcc tttaacgaaa gcttgattca ggtcatgagc aatattgttt tatacattgg
     6181 tctgattctt gtcatgtttt cgagaaatgt gacgctggct ctcatcacca ttgccagcac
     6241 cccattggct ttccttatgc tgattttcat cgtgaaaatg gcacgcaaat acaccaacct
     6301 ccagcagaaa gaggtaggga agctcaacgc ctatatggat gagagcatct caggccaaaa
     6361 agccgtgatt gtgcaaggaa ttcaagagga tatgatggca ggatttcttg aacaaaatga
     6421 gcgcgtgcgc aaggcaacct ttaaaggaag aatgttctca ggaattcttt tccctgtcat
     6481 gaatgggatg agcctgatta atacagccat cgtcatcttt gctggttcgg ctgtactttt
     6541 gaatgataag tctattgaaa caagtacagc cctaggtttg attgttatgt ttgcacaatt
     6601 ttcacagcag tactaccagc ctattatcca agttgcagcg agttggggaa gccttcagtt
     6661 ggcctttact ggagctgaac gaattcagga aatgtttgat gcagaggagg aaatccgacc
     6721 tgaaaaggct ccaaccttca ctaagttgca agaaagtgtt gaaatcagtc atatcgattt
     6781 ttcatacttg cctgataaac ctattttgaa agatgtcagc atttctgccc ctaaaggcca
     6841 gatgacagca gttgttgggc cgacaggttc aggaaaaacg actattatga acctcatcaa
     6901 tcgcttttat gatgttgatg ctggtggtat ttattttgat ggtaaagaca ttcgtggcta
     6961 tgacttagat agtcttagaa gcaaggtggg aattgtattg caagattcgg tcttgtttag
     7021 cggaacgatt cgagacaata tccgatttgg tgtgccagat gctagtcagg aaatggttga
     7081 ggtagcagca aaagcaaccc acattcacga ctatatcgaa agtttgcctg ataagtacga
     7141 tactcttatt gatgatgacc agagcatctt ttcaacaggg cagaagcaat tgatttcaat
     7201 cgctcgaacc ctgatgacag atccagaagt tctcattctc gatgaagcaa cttcaaacgt
     7261 agatacggtg acagaaagca agattcagca tgccatggag gtggttgtag caggtagaac
     7321 tagtttcgtc attgcccacc gcttgaaaac cattctcaat gcagatcaga ttattgtcct
     7381 taaagatgga gaagtcattg aacgtggtaa ccaccatgaa cttttgaagc taggtggctt
     7441 ttattcagaa ctctatcaca atcaatttgt tttcgaataa gaaagaagtt gtcctatgtg
     7501 ggcagctttt tcttgtccat aaaaaatgtt tatcacagcc ttaaaaaaaa catattagac
     7561 gaaagtcatt ttgagtgata tgataggact atcgttagca ttcgaaagga gaggcatcat
     7621 ggctagaacg gttgtaggag ttgctgcaaa tctatgtccc gtagacgcag aaggcaaaat
     7681 cattcattca tctgtatctt gtagattcgc agagatcatt cgtcaagtcg gtggtctccc
     7741 tttagtcatt cctgttggtg atgagtcagt tgtacgtgat tatgtggaaa tgattgacaa
     7801 actcattttg acaggaggcc aaaatgttca tcctcagttt tatggagaga aaaagaccgt
     7861 cgagagcgat gattacaatc tggtccgtga cgaatttgaa ttggcactct tgaaggaagc
     7921 gcttcgtcag aataaaccaa ttatggcaat ctgtcgcggt gtccaacttg tcaatgttgc
     7981 ctttggtgga accctcaatc aagaaatcga aggtcactgg caaggactac ctttcgggac
     8041 atctcactct attgagacag tagaaggaag cgtggtggct aagctatttg ggaaagaaag
     8101 tcaggtcaac tcagtccatc gtcaaagcat taaagatttg gcacctaatt tccgtgtaac
     8161 tgctattgat tcaagagacc aaactattga agcgattgag tctatcgacg agcaccgcat
     8221 tatcggttta cagtggcatc cagagtttct ggttaatgaa gaagatggca atttagaatt
     8281 atttgagtat ttattggatg aactgtaaca attggaacat ctggtcgttc tttcttttat
     8341 tttttcaaaa tttttagaat gtggtatttt acgcaaacgt ttgaattctg ataaaaattg
     8401 gagaaattcg acaaaaaaac ttgaaaaaaa cgaaggtaag cgttatgata gaaaagaaga
     8461 aatattggag gaagaacatg tcacatatta aatttgatta ttcaaaagtt ttagacaaat
     8521 ttgttgcacc acatgaagtg gaatacatgc aatcacaagt aacagcagca gatgaattga
     8581 tccgtaaagg aactggtgct ggtagcgact tcttgggatg gttggacctt cctgaaaaat
     8641 acgaccgcga agaatttgac cgcatcttga aagctgctga gcaaatcaag tcagacagcg
     8701 atgttttggt tgtgatcggt attggtggat cttaccttgg tgcaaaagca gcaatcgact
     8761 tcttgaatca ccattttgct aacttgcaaa caaaagaaga acgcaaagct ccacaaatcc
     8821 tttacgcagg aaactcaatc tcatctactt accttgctga cttggtagag tatgttgcag
     8881 acaaagactt ctcagtaaac gtaatttcta aatcaggtac aacaactgaa ccagcgattg
     8941 ctttccgtgt ctttaaagaa ctcttggtta agaaatacgg tcaagaagaa gctaacaaac
     9001 gtatctatgc aacaactgac cgccaaaagg gtgctgttaa ggttgaagca gacgctaacg
     9061 gttggggaac atttgttgtt ccagatgata tcggtggacg cttctcagta ttgacagccg
     9121 ttggtttgct tccaatcgca gcatcaggag ctgacataaa agctcttatg gaaggtgcga
     9181 atgcagctcg caaagactac acttcagaca aaatctctga aaacgaagct taccaatacg
     9241 cagctgttcg taacatcctt tatcgtaaag gctatgcaac tgagatcttg gtaaactatg
     9301 agccatcact tcaatacttc tcagaatggt ggaaacaatt ggctggtgaa tcagaaggaa
     9361 aagaccaaaa aggtatctac ccaacttcag ccaacttctc aactgacttg cactcacttg
     9421 gtcaatttat ccaagaagga actcgtatca tgtttgaaac agttgtccgt gttgacaaac
     9481 ctcgtaaaaa cgtgcttatt cctactttgg aagaagacct tgacggactt ggttaccttc
     9541 aaggaaaaga cgttgacttt gtaaacaaaa aagcaactga cggtgttctt cttgcccaca
     9601 cagatggtga tgtaccaaac atgtatgtga ctcttccaga gcaagacgct ttcactcttg
     9661 gttacactat ctacttcttc gaattggcaa ttgccctttc aggttacttg aatgctatca
     9721 acccatttga ccaaccaggt gttgaagctt ataaacgtaa catgtttgcc cttcttggaa
     9781 aaccaggatt tgaagaattg agcaaagaac ttaacgcacg tctataatag aagaaaagag
     9841 tggtttgccc actcttttta ctctctttat ccatagaaat tggactcagc caagacttgt
     9901 gatataatat agaaagcaaa aaggcagacg cctagataat aggagaaact atgtcaaaag
     9961 atatccgcgt acgttacgca ccaagtccaa caggactact acacatagga aatgctcgta
    10021 cagcattgtt taattacttg tatgcgcgcc atcatggtgg aacatttctc atccgtatcg
    10081 aagatactga ccgtaaacgc catgtcgagg atggtgaacg ttcacaactt gaaaaccttc
    10141 gctggttagg catggattgg gatgaaagtc cagaatcaca tgagaattat cgccagtctg
    10201 agcgtttgga cttgtatcaa aaatacatcg accaactatt agctgaagga aaagcctaca
    10261 aatcttacgt tacagaagaa gagttggcag ctgaacgtga acgtcaagaa gtagctggcg
    10321 aaacaccacg ctacatcaat gaataccttg gtatgagtga agaagaaaaa gcagcttaca
    10381 tcgcagaacg tgaagcagca gggatcatcc caactgttcg tttggctgtc aatgagtcag
    10441 gtatctacaa gtggcatgat atggtcaaag gcgatatcga atttgaaggt ggcaatatcg
    10501 gtggtgactg ggttatccaa aagaaagacg gttacccaac ttacaacttt gccgttgtta
    10561 tcgatgacca cgatatgcaa atctctcatg ttatccgtgg agatgaccat attgctaata
    10621 caccaaaaca gcttatggtc tatgaagctc ttggttggga agctccagag ttcggtcaca
    10681 tgaccttgat tatcaactct gagactggta agaagttatc taaacgtgat actaatacac
    10741 ttcaatttat cgaagattac cgaaagaaag gttaccttcc agaagcagtc tttaatttta
    10801 ttgctcttct tggttggaac ccaggtggtg aagatgagat tttctctcgt gaagaactca
    10861 ttaaactttt tgatgaaaac cgcctcagca agtcaccagc agcctttgat cagaaaaaac
    10921 tagactggat gagcaatgat tatatcaaga atgcagacct tgaaaccatc tttgaaatgg
    10981 caaaaccatt cttagaggaa gcaggccgtt tgactgacaa ggctgaaaaa ttagttgagc
    11041 tctataaacc acaaatgaaa tcagtagatg agattatccc attgacagat cttttcttct
    11101 cagatttccc agaattgaca gaagcagagc gcgaagtcat gacgggtgaa acagttccaa
    11161 cagttcttga agcattcaaa gcaaaacttg aagcgatgac agatgataaa tttgtgacag
    11221 aaaatatctt cccacaaatt aaagcagttc aaaaagaaac aggtattaaa gggaaaaatc
    11281 ttttcatgcc tattcgtatc gcagtttcag gcgaaatgca tgggccagaa ttaccagata
    11341 caattttctt gcttggacgt gaaaaatcaa ttcagcatat cgaaaacatg ctaaaagaaa
    11401 tctctaaata aagaggatac aataatggac atctgggaaa agatgtacga agaagcacag
    11461 aaactataca atccacatga agtatcagac tttgtttatg ccaatcatgt tgtagctgca
    11521 gtagaagcag aagatggaca aatatttaca ggattctgta tggagggaac ctgtggtgtt
    11581 ttccatctct gcgcagaacg ggcggccctc ttcaatacgt accaattttc aggacaaact
    11641 aaggttaaga aagtattagc ctttcgagac aaaccacctt atggtggaag ttcagccatg
    11701 ccttgcggtg cttgtagaga attcctttta gagcttaatg ctgaaaataa agatgcagaa
    11761 ttcatgatgg actataatat aagaaaaaca gttaaagtcg cagaactaat cccttattgg
    11821 tggggagaag aacgtgcttc taagtttaat gagcgataga agagtcagta taattctggc
    11881 tttttttact ataagttgaa aaaat
//
LOCUS       DAVBIC010000059        11491 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.059, whole genome shotgun sequence.
ACCESSION   DAVBIC010000059 DAVBIC010000000
VERSION     DAVBIC010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11491)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11491)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11491
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.059"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            complement(275..883)
                     /locus_tag="VQ664_001823"
     CDS             complement(275..883)
                     /locus_tag="VQ664_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001165927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HET2789936.1"
                     /translation="MQIKFIDKVSNLIMLNLLYVASVVTVIAIGSGESALIATLIKIV
                     RHEESYPYRDFANSFFKDYWKNLGAALISNLPILILLFSLFFLPYIPLPIYIISILRH
                     IGVIYIILHLIATTFLIPLIGRYNNTLKNSLHNSIMLAYKHFFIAVLIRIIEIIPVLL
                     FFILQNQLLVWITLMIFILPSITKYANAFLYNFIFSKYEKLN"
     gene            1049..1219
                     /locus_tag="VQ664_001824"
                     /pseudo
     CDS             1049..1219
                     /locus_tag="VQ664_001824"
                     /inference="COORDINATES: protein motif:HMM:NF013577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
     gene            1208..1819
                     /locus_tag="VQ664_001825"
     CDS             1208..1819
                     /locus_tag="VQ664_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001821036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HET2789937.1"
                     /translation="MTKDILELESQKMSSDTFIDEIKNNYLSIVESTRKLIDGRQIEL
                     AIKLIREANQILMIGVGSSGNAAREFESSLLRIGIISKTVIDTHFQLMHTALLKDNDL
                     IIAFSLSGSTKEVEETLLNAKRKNVKIISITNYSSRNIAKLSDCVLLTSKKESYLEGG
                     SLMAKASQLFIIDVICTRLSLINYEDTICKKEEIASLLSNKVE"
     gene            2536..3222
                     /locus_tag="VQ664_001826"
     CDS             2536..3222
                     /locus_tag="VQ664_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HET2789938.1"
                     /translation="METKKIKNLKGQIIVSCQALEGEPLYTPNGGVMPLLAKAAFQAG
                     AKGIRANSVRDISEIKEEVDLPIIGIIKRDYDGFEPFISATMKEIDELVSEGVDILAL
                     DCTNRSRPGYDNITDFIHDIKVKYPNQLLMAAISTFEEGKVAAESGVDFVGTTLSGYT
                     PYSPKKDNPDFELVERLVKELDVPVIAEGRISTPEQARKMLDLGAYAVVVGGAITRPL
                     EIAKKFIEVV"
     gene            3223..4155
                     /locus_tag="VQ664_001827"
     CDS             3223..4155
                     /locus_tag="VQ664_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001071049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2789939.1"
                     /translation="MNQEILKKSKIQLTVEHIQKYWILYLMMIPATVLLILFTYGPMY
                     GIIMAFQDFTVFKGYTGSPFVGLKHFQRLFSDPLFYRLFKNTFMVGVLDFLFFFPAPL
                     IFALILNEVRKVRFKSVVQSISYLPHFIPLVVMVGIIFELFGSYGIINSLLSSLGMEP
                     ISFFTKSEWFLPLYIGSGVWKTIGWGSIIYMGALTNIDSTLYEAADMDGANRWHKMWH
                     VTLPSLRPTVVTLFILNAGGIMQVGFEKVFLMSSPATYEVSDVLSTYVYRQGILNSDF
                     SYSAAVGLFNNIVALLFVLLANKIAKKLGEEGIV"
     gene            4166..5095
                     /locus_tag="VQ664_001828"
     CDS             4166..5095
                     /locus_tag="VQ664_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000577774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET2789940.1"
                     /translation="MIFSKNTKKSNRDKETFVDYLFIFILIIITLLMLYPLWWVVMTS
                     LSEPVWLSKNVVKLFPLKIDITAYKFIFGDSKLWQAYGNSVLYAALSTIVSVAVCSMY
                     AYPLTIPEIRGKKFWNTLILIPMFFSGGMIPLYIQVANLGLLNTAWALVLPGAVSTYY
                     IILFRTQFKSIPMELRESARIDGASEFRIFWNLVLPLSKVIFMIIALYCIVGSWNSFT
                     PPLLYLNDDTKMPLSIYLRNLVVTNTTDTAELSLSAGNTYYQQIAAQGGGIGMRIAIK
                     MGTIVVSVIPIMMIYPFIQKHFVKGILLGSVKG"
     gene            5109..6548
                     /locus_tag="VQ664_001829"
     CDS             5109..6548
                     /locus_tag="VQ664_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001178946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789941.1"
                     /translation="MQNLKKYLLLDSGLVVGYTLENAQLKLNKLKKDTENNPLFGEEY
                     FAENPKLWEVRFDNSYPNVIYDKELKLYRCWYQTFVSDEASEETPLAERGEKEYIVKS
                     SRMTALCYAESKDGVKWEKPNLNLVKFKGSKDNNIVLMHAHGAGIMLDEQELDPKKRY
                     KLVSKLEFSPNLHYMVVVFSEDGIHFDEPIPWKKWNPAADSHNFPFRDPKTGKYAVIT
                     RTWANNVRLSAITFSDDFINWSEPKEILRGDGFEDQIYSMPVISYADIYLGFASMYHE
                     GDTLNENYDKVDLELKFSANLEQWDSVCKGDYLIERGGGVYPQNADFDASCIFTAAPI
                     IEDDKIWFYYMGGNGNHTGFRESSLARGYIKKDQFAYYTNKREGIPAKISTVSFQTYD
                     DEIYILADIPENGYIKVAVGTKYGNAYSDFGQEDISLVQVSDGKYKLEFNKKSILDLG
                     NSPVAFKFEIENAKLYGIEGSIQQHYLKY"
     gene            6617..8194
                     /locus_tag="VQ664_001830"
     CDS             6617..8194
                     /locus_tag="VQ664_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET2789942.1"
                     /translation="MVKLNKVLKGSVAFLSASLLLAACGNNANSKPAEKTADGKTKIS
                     FLSTWQINDVRPPKDETLVGQWLEEQLGIDIDLVTIPGEGVSSKVNSLITSNQLPTVL
                     LTTGDKSDIAGINKLGKQGAFLDLSQHMDKLPNYKKYLEKNNALAQIEDDEKHIYAFT
                     KFFTDENIMYTTPILRKDLLVGSEFEDLSKIKTVDDYTKVLKYLTEKQGSPAFIQRNG
                     YEGFMKRVTPLWNLSHRTYYDYESDSYKHPVEQPQLKQFVEWLKELRKDNVLHPDWAV
                     MKDETWEGLLASNKGSFTVDRMNIIGDNNFDKSFDWQPLVYPEINGKRYLQPKTPYIS
                     DSGWVINANAPKEEIDKALEFFNFLYADENQEKLAIGFEGKTFTRENPNTQAGIKWLI
                     QIYGENAGNDKAELLFKHGNQAFTRVQTKLDIEAQPGTFPKVMYDQVDKIKKDLGGFR
                     PDTPVLSFTTEELDVLTKSEAGLNTFFDENIIKFIEGQRDMSEWDSFINEAKSKDLDK
                     VTKVYNDAYKRVKDRMK"
     gene            8254..9714
                     /locus_tag="VQ664_001831"
     CDS             8254..9714
                     /locus_tag="VQ664_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000272432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HET2789943.1"
                     /translation="MYDVVIIGAGSSGALAAIASGRLGLKTCLIEKGSRIGGVPINTL
                     MGSFANLYFDDSGRVNASKIVGELIERIIKKGGTVFNSMEELMNVNDFYQITIPYQPE
                     VYESVLTDMLIESKVDILLNVEVNNIIYDSKNIKSLEILSNQEVKLIDSKVFIDATGN
                     ATIASASGADVYEKNSSYGCLMRVGGVDISKTIEHIEKTKQWNYIEGYNQWLEEVLAN
                     RKYRATGAVLKDPVSYDHAPMLSKDDHFMNDEKWNYIKERWEKFRFIYTLEVSLFRNE
                     LKKAVESGDFNFEIYHDDKSGVTMNGDGISYGSWGQNVALINVAKAFGFNPKYMEDES
                     HANILSRKYNLTFLSFLKKYVPGFENSFILDQGTRATNRSCRHIDNSSMMDEILDFPM
                     YTFKTMYSYQTPKEITYKSIVGGKLNNLFVIGKGAYQSESFRSQISCMLMGISSAAAA
                     KTIIEDKSNTLNINRDLFKSNLDILFTWEFSNWITD"
     gene            9736..10191
                     /locus_tag="VQ664_001832"
     CDS             9736..10191
                     /locus_tag="VQ664_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001000318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT domain-containing protein"
                     /protein_id="HET2789944.1"
                     /translation="MNDTNKNQYFVYEFDTSFVEMSYSQFFEGYCILFSKEPYPSLSD
                     MPMEFRKEFLMEMSILGDAMLEVLNAYRINYDILGNSTPVLHAHLFPRYMWEEEERRK
                     TVVHRYDSSVFSNPEFEFTIEKHGPIIKKLRSAIDRHYREYQQLLDDSN"
     gene            10278..10683
                     /gene="cdd"
                     /locus_tag="VQ664_001833"
                     /pseudo
     CDS             10278..10683
                     /gene="cdd"
                     /locus_tag="VQ664_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221146.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
     gene            10696..11145
                     /locus_tag="VQ664_001834"
     CDS             10696..11145
                     /locus_tag="VQ664_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HET2789945.1"
                     /translation="MELVEFKNGHVNTVHEHIAITKVKEFLNNHDILKDKGGIHKIST
                     DFFYNIIDMETTTEENRPWESHKEYYDVHYLLNGEETILYNFLSQMELSEYKVDDDWQ
                     QMNGTALFSIKLKKDMLLLLEPNDAHRTGLLVEEPLNIKKVVFKVKI"
     gene            complement(11257..11491)
                     /locus_tag="VQ664_001835"
                     /pseudo
     CDS             complement(11257..11491)
                     /locus_tag="VQ664_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
BASE COUNT         4086 a         1446 c         2072 g         3887 t
ORIGIN      
        1 acttagttct gtgcagtaca gaactaaatc ctttggataa attatttgtc taattttttg
       61 gggtcagtac agtattaaat accatgatct tatgcgtttt ataataaaaa atctgttctt
      121 gttttatttt tagaaaattt actaaagact aaaaatatta tgaataattt aaaaaatagt
      181 caggttatat agttttttga aattaaaatt attttatcgt tgaaattagt taaaaatttt
      241 tataaaatca agatgcaagg ctatgagatg ttctctagtt taatttttca tacttcgaga
      301 atataaagtt atataaaaat gcattagcat attttgttat tgagggaagt ataaaaatca
      361 ttaaagttat ccaaactagt aattgattct gtaatataaa gaagagtaga actgggataa
      421 tttcaataat tctaataaga acggcaataa aaaaatgttt ataggctaac atgattgaat
      481 tgtgtagaga attttttaaa gtgttattat atctaccgat taaaggaatt agaaatgttg
      541 ttgctattaa atgaagtatg atatatatta ctccaatatg tcgtaagata gaaatgatat
      601 atataggtaa tggtatgtag ggtaggaaga acaaactgaa taataagatt aaaattggta
      661 aattagatat taatgctgct cctaaatttt tccaataatc tttaaaaaaa ctgtttgcga
      721 agtctctata gggataggat tcctcgtgtc gtacaatttt tattagagtt gctattaggg
      781 cactttcacc tgatccgata gcaataactg ttactactga cgctacatag agtagattta
      841 acattataag atttgaaact ttatcaataa attttatctg catctttaac tcctgctgtt
      901 tttatactta taatatcaca tcatttgagt ttcatcaact ttgaatacat taagaaagaa
      961 tataactatg aggaaaggaa aaaattatta tgaataaatc caaaaaatat aaagaaagaa
     1021 ttcattatga atacgataat cttactaaat cagagaaaaa attgctgact atattttagt
     1081 tagagatagt gaaatagttt atgaaacgtc ttcagaaatt gttagtaaag taaaagttgg
     1141 agagggaact cttaatcgat tttgcaaaaa gattggatac tctggttttc aggaactaaa
     1201 attaaaaatg acgaaagata tattagagtt agaatctcaa aaaatgagta gtgacacatt
     1261 tattgatgaa ataaaaaata attatttatc tattgtggaa agtacaagaa aattaattga
     1321 tggtagacaa atagaattag ctataaaatt aataagagaa gcaaaccaga ttttaatgat
     1381 tggtgtgggt tctagtggaa atgcggctag agaatttgag agtagtttgt taagaattgg
     1441 aataataagt aagacggtaa ttgataccca ttttcaactc atgcatactg cgttattgaa
     1501 agataatgat ttgataatag cgtttagttt atctggttcc acaaaagaag ttgaggaaac
     1561 tttattaaac gcaaaaagaa aaaatgttaa aattatttca ataacaaatt attcgtccag
     1621 aaatatagca aaattatctg actgcgttct tttgacatca aaaaaagaat cttatttaga
     1681 gggtggtagt ttaatggcta aggcttctca actattcata attgatgtaa tatgcactag
     1741 actctcttta ataaattatg aagatactat atgtaaaaaa gaagagattg cttctttgct
     1801 gtcaaataaa gtggaataaa tcaataattt ttaaatttta ataaaaattt tttaaaataa
     1861 attaaaaaac gatcctaaaa gggtcgtttt tttgctaaag ttttaaaaat aaacaataat
     1921 taagattata gtgcgttgaa tctatattag gacataacaa ttcttaaatc attgttagaa
     1981 attagtttga attttccaat caatttgttc gatttttaca tcattgcatt atatcacgtg
     2041 actattaacc ttgttttctc ctaaaattga ttttcttctt ttcttatctt gtccactcga
     2101 aacaagtatt gtaagaattt gattattttt gaaagtactt ttaatatatt tgagatagtt
     2161 aaaaaagatt tgaaactaaa ttccaaatta gaaaaagact tgaaatgcta aaaaaaaaaa
     2221 gtatactcta attgaaaacg gtaacaaaac taatttagag aatgaaatat agagtatttc
     2281 tctcttaaaa gtttttggtg aaacgagatg tagaaaggag atttagccaa agagtctatt
     2341 agtgctagaa taatagatta gaattatagt gtattgaatc tataacagta cgccttaaat
     2401 gctaaaatat ttctataaat taatttaact ttcctgatag ggctgttcat atcttatttc
     2461 aattcactat ataaataaaa ttgtagtaga tgttattgaa ttagtaaaaa aaataaaaaa
     2521 acggaggttt tctgaatgga aactaaaaaa attaaaaatt taaaaggtca aataattgtt
     2581 tcctgccaag cgttagaagg agagccactt tatactccaa atggaggagt gatgccgtta
     2641 ttagcaaaag ccgcctttca agcaggcgct aaaggtattc gtgctaattc tgtccgcgat
     2701 atttcagaaa taaaagaaga agttgactta ccaattatag gtatcataaa aagagattac
     2761 gatggctttg aaccttttat ttcagcaact atgaaagaga ttgatgaatt agttagtgaa
     2821 ggagtagaca ttttagcttt ggattgtact aatcgttcaa gaccaggtta tgataatatt
     2881 actgacttta ttcatgatat taaagtcaag tatccaaacc aattattaat ggctgctatt
     2941 tctacttttg aagaagggaa agtagctgct gaatcgggag tagattttgt gggtacgaca
     3001 ttatctggtt atacaccata tagccctaaa aaagataatc ctgattttga gttagttgaa
     3061 agattggtaa aagagcttga cgtaccagtt attgctgaag gaagaataag tactccggaa
     3121 caagctagaa aaatgttaga tttaggtgct tacgcagtgg ttgttggagg agctatcact
     3181 cgtcctttgg aaatagcgaa gaagtttatt gaggtagttt agatgaatca agaaatatta
     3241 aaaaagagta agattcaatt gacagttgaa catattcaaa aatattggat tttatattta
     3301 atgatgattc cagcaactgt tctactaatt ttatttacgt atggaccaat gtacggcatt
     3361 attatggcct ttcaagactt tactgtcttc aagggatata ctggaagtcc atttgtcggt
     3421 ttaaaacatt ttcaaagatt gttctcagat cctttgtttt atagattgtt caagaatacg
     3481 ttcatggtag gggttttaga ttttttattc tttttcccag ctccgcttat ttttgcactc
     3541 atattaaacg aagtcagaaa agtaagattt aagagtgtag ttcaatctat tagttatctt
     3601 cctcatttta ttcccctagt ggttatggtt ggtattattt ttgaactatt tggttcatat
     3661 ggtattatta acagtttact ttcatcactt ggaatggagc caataagttt ctttacaaaa
     3721 tctgaatggt tcttgcctct ctacattggt tcaggagtat ggaaaacaat aggttggggt
     3781 tctatcattt atatgggagc attaaccaat atagattcaa ctttatatga agcagcagat
     3841 atggacgggg ctaatagatg gcacaaaatg tggcatgtaa ctctaccaag tttaagacct
     3901 acagtagtta ctttgtttat actaaatgct ggtggtatca tgcaagtagg atttgaaaag
     3961 gtattcttga tgtctagtcc tgcaacatat gaagtatctg atgtattatc tacttatgtt
     4021 tatagacaag gtattttaaa ttctgatttc agttactcag ctgcagtagg attatttaat
     4081 aacatagtag ctttgttatt tgttttatta gctaataaga ttgctaaaaa acttggcgaa
     4141 gaaggaattg tataaggggg gtaaaatgat tttttcaaaa aatacaaaaa agagtaatag
     4201 agacaaagaa accttcgttg attatctctt tatattcatt ttaataataa taaccttact
     4261 tatgttgtat ccattatggt gggtagtgat gacgtcactt tcagaaccag tttggctatc
     4321 taaaaacgtt gttaaattat ttcccttaaa aatagatatt actgcatata agtttatttt
     4381 tggggattct aaactatggc aagcatatgg taatagtgta ttgtatgctg cactatctac
     4441 aattgttagt gttgcggtat gtagtatgta tgcctatcca cttacaattc ctgaaattag
     4501 gggtaaaaaa ttctggaata ctcttatttt gattccaatg ttctttagtg gaggaatgat
     4561 cccgctttat atacaagttg caaacctcgg tttattgaat actgcttggg ctcttgtttt
     4621 acctggtgct gtttctacat attatataat tttgtttaga acacagttta aatcaatccc
     4681 aatggagctt cgtgagtctg ctagaattga tggggcaagt gaatttagaa ttttttggaa
     4741 tttagtatta ccattatcaa aagttatttt catgattata gcactttatt gcatagttgg
     4801 ttcatggaat agttttactc ctccattact ttatttgaat gacgacacta agatgccttt
     4861 atctatttat ttgagaaatt tagtcgttac aaatacaact gatactgctg aattatcact
     4921 ttctgcaggt aatacatatt accaacaaat tgctgctcaa ggtggaggta ttggtatgcg
     4981 tattgctatt aagatgggta ctattgttgt tagtgttatt ccaattatga tgatttatcc
     5041 atttattcag aaacattttg ttaagggaat cctgctaggt tctgtgaaag gttaataagg
     5101 taattatttt gcaaaattta aaaaaatatc ttttattaga tagcggttta gtagttgggt
     5161 atacattaga aaatgctcaa ttaaaattaa ataagctaaa aaaagatact gaaaacaatc
     5221 cactatttgg tgaagagtat tttgccgaaa atcctaaatt atgggaagtt cgttttgata
     5281 attcatatcc aaacgttatc tatgataaag aattgaaatt atatagatgt tggtatcaaa
     5341 catttgttag tgatgaagca agcgaagaga ctcctttagc agaacgtgga gagaaggaat
     5401 acattgtcaa gtcatctaga atgacagcac tttgctatgc tgaaagtaaa gatggagtaa
     5461 aatgggaaaa accaaatctc aatctagtaa aatttaaagg ttcaaaagat aataatattg
     5521 ttctgatgca tgcacacggt gcaggtatca tgctagatga acaggagttg gatcctaaga
     5581 aacgatataa attagtttca aaattagaat tttctccgaa tcttcattac atggttgttg
     5641 ttttttcaga agacggtatt cattttgacg aacctattcc atggaaaaaa tggaatcctg
     5701 cagcagatag tcataatttt ccatttagag atccaaaaac tggtaaatac gctgttatta
     5761 caagaacctg ggcaaataac gtacgtctaa gtgcaattac tttcagtgat gattttatta
     5821 attggtcaga acctaaagaa atccttaggg gagatggatt tgaagatcaa atttattcta
     5881 tgccagtaat ttcatacgcg gatatctatt taggttttgc ttcaatgtac catgaaggcg
     5941 acactttaaa tgaaaactat gataaagtag acttagaatt gaaattctct gctaatttgg
     6001 aacaatggga tagtgtatgt aagggcgact atctcattga aaggggaggt ggagtatacc
     6061 cgcagaatgc tgattttgat gctagttgta ttttcacggc tgctccaata attgaagatg
     6121 ataagatttg gttctactat atgggtggaa atggtaatca cactggcttc cgagaaagtt
     6181 cattagctag aggatatatt aagaaagacc aatttgctta ttatactaat aagagagaag
     6241 gaattccagc taaaatatct acagttagct tccaaactta cgatgatgaa atttatatct
     6301 tagctgatat tcctgaaaat ggttatatta aagttgcggt aggtactaaa tacggtaatg
     6361 cttattcaga tttcggtcag gaagatatct ctcttgttca agtttccgat ggtaagtata
     6421 agttggaatt taataaaaaa tctatcttag atttaggtaa ttctccagtt gcgttcaaat
     6481 ttgaaatcga gaatgcaaaa ttgtatggta ttgaaggtag tattcagcaa cactatctca
     6541 aatattaacc agaataattc gttaacaaat aatctctata ttagtggaga tagatatata
     6601 aaatggaggt cttattatgg taaagcttaa taaggtatta aaagggagtg ttgcattcct
     6661 gagtgcaagt ttattgctag cagcttgtgg caataacgct aattcaaagc ccgctgaaaa
     6721 aacagctgat ggtaaaacga aaatttcgtt tctatctaca tggcaaatta atgatgttcg
     6781 tccgcctaaa gatgaaacac ttgttggtca atggttagaa gaacagctag gtattgatat
     6841 tgatcttgta actattcctg gcgagggagt aagttctaaa gtaaattctc ttattactag
     6901 taaccagtta ccgactgttt tgttgacaac aggagataag agtgatatcg ctggtatcaa
     6961 caaacttggt aaacagggtg cattcttaga tttgtcacaa cacatggaca aactaccaaa
     7021 ctataagaag taccttgaaa aaaataatgc attagctcaa atagaagatg atgaaaaaca
     7081 tatttatgct ttcacaaaat tctttactga tgagaatatc atgtatacta caccaattct
     7141 gagaaaagac ttacttgttg gttcagaatt tgaagatctt tcaaaaatta aaactgttga
     7201 tgactataca aaagttttga aatatttgac tgaaaaacaa ggttctccag catttattca
     7261 acgtaatggc tatgaaggct tcatgaagcg agttacacca ttgtggaatt taagccatcg
     7321 tacatactat gactatgaat cagattcata taaacatcca gttgaacaac ctcaattgaa
     7381 acaattcgtt gaatggttga aagaattacg taaagataac gtacttcacc ctgactgggc
     7441 agttatgaaa gatgaaactt gggaaggtct attggcttct aacaagggtt cattcactgt
     7501 tgaccgtatg aatatcattg gagataataa ctttgataaa tcatttgatt ggcagccact
     7561 tgtttatcca gaaattaatg gaaaacgtta tttgcaaccg aaaacaccgt acatttctga
     7621 ttcaggttgg gtaatcaatg ccaatgcacc aaaagaagaa attgataaag cgttagaatt
     7681 ctttaatttc ttatacgctg atgaaaatca agaaaaactt gctattggat ttgaaggtaa
     7741 aacatttaca cgtgaaaacc ctaatactca agcaggtatt aaatggttga ttcaaattta
     7801 cggtgaaaat gctggaaatg ataaagcaga actgctgttt aaacatggta accaagcatt
     7861 tactcgcgtt caaactaaat tagatattga ggcacagcca ggaacattcc ctaaagttat
     7921 gtatgatcaa gtagataaaa ttaagaaaga tttaggtggt tttagaccag atactccggt
     7981 tctttccttt acaactgaag aattagatgt tttaactaaa tctgaagcag gattaaatac
     8041 tttctttgat gaaaatatta ttaaattcat tgaaggacaa agagatatga gtgagtggga
     8101 ttcatttatc aatgaagcta aatctaaaga cttggataaa gttacaaaag tatataatga
     8161 tgcctacaaa cgtgtcaaag atagaatgaa atagactaaa tggtagctct ctggtttttc
     8221 agagagctac tactgcctga gggggagtaa gctttgtatg atgtagtaat tataggtgca
     8281 ggaagttcgg gcgcattggc tgcaattgct tcggggcgtc tagggttaaa aacttgtcta
     8341 atagagaagg gaagtagaat tggtggagtt cctattaata cactaatggg gtcatttgct
     8401 aatctatatt ttgatgattc tggtagagta aatgcaagta aaattgttgg ggaattaata
     8461 gaacgtatta tcaaaaaagg tggtactgtc tttaactcta tggaagaatt gatgaatgta
     8521 aatgattttt atcagattac aattccctat caaccagaag tttatgaatc ggttttaact
     8581 gatatgttga ttgagtctaa agttgatatt ttactaaatg ttgaagttaa taatattatt
     8641 tatgatagta aaaatattaa aagtcttgaa attttaagta atcaggaagt taaattgatt
     8701 gattctaaag tttttattga tgctacaggg aatgcaacaa ttgcttctgc tagtggagct
     8761 gatgtttatg aaaaaaattc ttcttacggt tgtttaatga gagttggagg agttgatatc
     8821 tcaaagacta tagaacatat tgaaaaaaca aagcagtgga actatataga aggatataat
     8881 cagtggttag aagaagtatt agcaaatcga aagtacagag ccactggagc agttttaaaa
     8941 gatccagttt cttatgatca tgcccctatg ctttcaaaag acgaccattt tatgaatgat
     9001 gaaaaatgga attacattaa agaaagatgg gaaaaattta gatttattta cactttagaa
     9061 gtatcactat ttaggaatga attaaaaaaa gctgtagaat ctggggattt taattttgaa
     9121 atttatcatg atgataaatc tggagtcact atgaatggcg acggtataag ctatggttca
     9181 tggggtcaaa atgtagcatt aattaatgtt gcaaaagcat ttggattcaa tcccaaatat
     9241 atggaagatg aatcacatgc taatattctt tctagaaaat ataatttaac atttttatct
     9301 tttcttaaaa aatatgtacc aggttttgaa aattctttta tccttgatca gggaactaga
     9361 gctactaaca gatcatgtag gcacattgat aattcatcta tgatggacga aattcttgat
     9421 tttccaatgt atacatttaa gactatgtat agctatcaaa ctcctaaaga aataacgtac
     9481 aaatcaattg taggtggaaa attgaataat ttgtttgtaa taggtaaagg tgcttaccaa
     9541 tccgaaagtt ttagatcaca aattagttgt atgttaatgg ggatatcatc agcagcagcg
     9601 gcaaaaacta ttattgaaga taaaagcaat actctaaaca ttaatagaga tttgtttaaa
     9661 tcgaacttag atatattatt tacatgggag ttttctaatt ggattactga ttaacaaata
     9721 ataagggaat attaaatgaa tgatactaat aaaaatcaat actttgttta tgaatttgat
     9781 actagctttg tagaaatgtc ttattctcag ttttttgaag gatattgtat tcttttttca
     9841 aaagaaccct atccttcttt atctgatatg ccaatggaat ttagaaaaga atttttaatg
     9901 gaaatgagta tattaggtga tgcgatgctt gaagtgttaa atgcctatag aattaattat
     9961 gatatcttag gaaattcaac acctgtactt catgctcatt tatttccgag atacatgtgg
    10021 gaagaggaag agagaagaaa aactgtagtt catagatatg attcttcagt ttttagcaat
    10081 cctgagtttg aatttactat agaaaagcat ggaccaatta ttaaaaaact gaggtctgct
    10141 attgatagac attatagaga gtatcaacaa ttattagatg attcaaactg aactccacat
    10201 tttcgattag atttaatacc ttgtatatta caactaggtt gtggatgata taattttttg
    10261 aaaaatatat tttaggaatg acttataaag caattatatc agaggctatt aaatcaatgg
    10321 ccaaagctta tgctccttat tctgatttta aggttggagc tgcgttagta actgaagata
    10381 aaaaattttt tctggatgta atatagaaaa tgctgctttt tctcctactt gctgtgcaga
    10441 acgagtatct ttttataaag ctgtatttaa aggagaacgt tcgttttcaa gaacatgtat
    10501 tgtaggtgga aaaaatggta tcttatcatc ttttatagca ccttgcggag tgtgtcgcca
    10561 ggtaatgata gaatttgtaa tcctgattca tttgaagtta tattggctag tgatgttgat
    10621 acttataaag tatataaact taaagaacta ctaccagtta gttttaatca agaaaattta
    10681 taacaggagg gaactatgga attagttgaa tttaaaaatg gacatgttaa tacggttcat
    10741 gagcatatcg caataacgaa agtaaaagag tttctaaata atcatgatat attaaaagat
    10801 aaaggtggca tacataaaat ttctactgat ttcttttaca atataattga tatggaaact
    10861 acaactgaag agaatagacc gtgggaaagt cataaggaat attatgatgt ccattatctg
    10921 ttaaatggag aagaaacaat tttatataac ttcttgtctc aaatggaatt gtctgaatat
    10981 aaagtagatg atgattggca acaaatgaat gggacagctt tatttagtat taaattaaag
    11041 aaagatatgt tacttttgtt ggaaccaaac gatgcacata gaacaggcct attggttgaa
    11101 gaaccactta atattaagaa agttgttttt aaggtaaaaa tttaactgaa agtactttcg
    11161 gggattaaga attttaaaat atttaagaaa ttgtattcta aagttctaaa attatagata
    11221 tttaatttaa agcttgttaa aatagaatag taacactcat ctgctttcaa aaagcattct
    11281 attccatctc cgattaacga tggactttat cacctccttc tccagtcctt gtatgacatc
    11341 ttggagttga ttcatgacat cttccaaagt tcgaaaggct ttattcttaa atccacgttt
    11401 atgaatctct ttccacactt gttcgatggg ttcatctctg gtgtgtatgg aggaataaat
    11461 gcaaaaccaa tattagtcgg agtctttaag g
//
LOCUS       DAVBIC010000060        11464 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.060, whole genome shotgun sequence.
ACCESSION   DAVBIC010000060 DAVBIC010000000
VERSION     DAVBIC010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11464)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11464)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11464
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.060"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            1..738
                     /locus_tag="VQ664_001836"
                     /pseudo
     CDS             1..738
                     /locus_tag="VQ664_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(854..1657)
                     /locus_tag="VQ664_001837"
     CDS             complement(854..1657)
                     /locus_tag="VQ664_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic/DOC family protein"
                     /protein_id="HET2789946.1"
                     /translation="MQSTYNIDNPNLSYEAKRDLWRIGFGLQKVDNLVPSAYMESLAE
                     KQSRGELTYEQVYEDATAYHHTIDASTEEADLVSLRIVELLSRRGFSFSPATLLAIHK
                     ELFQDIFEPSIPVGQFRQTNITKNEPVLNGESVVYSDYSMIQMTLDYDFNQEKQVAYA
                     TLTQADVVKQIQHFISGIWQIHPFREGNTRTVTVFLIQYLREFGFDIDNTPFQQHSKY
                     FRDALVLDNAKILQRRSEFLTAFFENLLLGGQNDLSSEKMYLDLDLDFS"
     gene            complement(1936..2691)
                     /locus_tag="VQ664_001838"
     CDS             complement(1936..2691)
                     /locus_tag="VQ664_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3883 domain-containing protein"
                     /protein_id="HET2789947.1"
                     /translation="MSKHPHYELLNLIGYGLAKFDKLFIKEFQCSSKSEFYRYVVSLG
                     IAETTGVVKNRMDLFDPYFDNNRKGWWQKAEVYRFRKDLIDMMFGNEDVHSYAEIVKM
                     LLASEGKKTGITIVEKPIVRTKFKRLQETGMEAENYFILHFDKEEKFQGGQLTDARLY
                     GDGYDFQVDVQEYSYLAEVKGIRKSKGRVRLTAKEFEKVKEFQSDFILSLVTNLDDIP
                     KLVLIDNPLKHFEFKKNIIKNEIIEYRSVEDLY"
     gene            complement(2761..5412)
                     /locus_tag="VQ664_001839"
     CDS             complement(2761..5412)
                     /locus_tag="VQ664_001839"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HET2789948.1"
                     /translation="MSKELSSKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ISRYDLGRESFLTKVWEWKDEYSTTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPKFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNELAFEFSGMDRFEARKAVVAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTDDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNEAGEIYVGEEAPAGDGWKQDEDVLDTWFSS
                     ALWPFSTMGWPNTETTDFKRYYPNSTLVTGYDIIPFWVSRMIFQGIEFTGKSPFKNAL
                     IHGLIRDEEGRKMSKSLGNGIDPMDVIDKYGTDSLRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNEGLTLDVAHDNVTKVATGEAGNVTDRWILHNLNETIAKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEEEKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQISEGSIVTAEYPTVNPAFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIFLPLVDLLNVEEELARLEKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     ERDKQADYQAKYDATVARIDEMKKLVK"
     gene            complement(5405..5983)
                     /locus_tag="VQ664_001840"
     CDS             complement(5405..5983)
                     /locus_tag="VQ664_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000550018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HET2789949.1"
                     /translation="MHLFIIGAPASGKMTIGQELSRLTDATLFYNHQAIDFALEIYQD
                     YTEEMWEFVRGITFSFLGASARNQRSVILTDVIDFSNQYQLMYLKQIQNLLDDYHQEI
                     LFVELETSLEECIRRNRTENRLKHKPLKRHIEVSEREILETAETLQLNSQYQPNELHH
                     YFKINNTNLSAEEAAKQIQNKINKIEKGHTHV"
     gene            complement(5983..6453)
                     /locus_tag="VQ664_001841"
     CDS             complement(5983..6453)
                     /locus_tag="VQ664_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2789950.1"
                     /translation="MARTELPDKIETERLVLRVRTVADAEDIFDYASLPEVAYPAGYG
                     IVVKGTDKIVGSVDFNHRHEDDVLEIGYTLHPDYWGRGYVPEAARALIDLAFKDLGLH
                     KIELTCFGYNLQSQRVAEKLGFTLEARIRDRKDAQGNCCDDLRYALLKSEWEVI"
     gene            complement(6440..7018)
                     /locus_tag="VQ664_001842"
     CDS             complement(6440..7018)
                     /locus_tag="VQ664_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HET2789951.1"
                     /translation="MKQSFKTNKLYYGFPVFILGYQDQNFGYNITTCSSSYSLGDWVV
                     IGVVARENAAEQIKQYQKFTVNISDETSMLAMEQAGFISHQEKLERLGVHYEISERTQ
                     TPILDACPLVLDCRVDRIVEEDGICHIFAKILERLVAPELLDEKGHFKNQLFAPTYFM
                     GDGYQRVYRYLDKRVDMKGSFIKKARKKDGKN"
     gene            complement(7301..7696)
                     /locus_tag="VQ664_001843"
     CDS             complement(7301..7696)
                     /locus_tag="VQ664_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HET2789952.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQSAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASDFK
                     NWTEKELLALKGIGPATIKKLKENGIKFK"
     gene            complement(7792..8046)
                     /locus_tag="VQ664_001844"
     CDS             complement(7792..8046)
                     /locus_tag="VQ664_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HET2789953.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKVGKGFHDLPEGLFGERNY"
     gene            complement(8055..9389)
                     /locus_tag="VQ664_001845"
     CDS             complement(8055..9389)
                     /locus_tag="VQ664_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HET2789954.1"
                     /translation="MTDEWIHILRDILLELHNGASPESVQDRFDATFTGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVLDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYELMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTVKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWLQIAEESDAYGYAIIRPSEKWVPERQSFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKEDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKTIMKRLREGSKDKY
                     EMWFKSESRGKFVHITYAAVHDEDGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            complement(9389..9622)
                     /locus_tag="VQ664_001846"
     CDS             complement(9389..9622)
                     /locus_tag="VQ664_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HET2789955.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLTGTPMDKIVRTLEANGYEVIGLD"
     gene            complement(9891..10031)
                     /locus_tag="VQ664_001847"
     CDS             complement(9891..10031)
                     /locus_tag="VQ664_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789956.1"
                     /translation="MKFFWTILAILFIKPIIGIVKFFWMIISFAVQLLFYKILDWFFK
                     LI"
     gene            complement(10028..10210)
                     /locus_tag="VQ664_001848"
     CDS             complement(10028..10210)
                     /locus_tag="VQ664_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789957.1"
                     /translation="MNPIKAFAKIYGNYFLTVQGVKVMKTIKKDDHVVVGLGKLFIAD
                     KLMDTARWLIKPEERE"
     gene            complement(10212..10995)
                     /locus_tag="VQ664_001849"
                     /pseudo
     CDS             complement(10212..10995)
                     /locus_tag="VQ664_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         3405 a         2505 c         2111 g         3443 t
ORIGIN      
        1 aaaacagata aggaccaaga gcttaaagct gaaattcaat ccatttttat cgaacacaag
       61 ggaaattatg cttatcgctg tgttcattta gaactaagaa atcgtggtta tctggtaaat
      121 cataaaagag ttcaaggctt gatgaaagta ctcaatttac aagctaaaat gcgacagaaa
      181 cgaaaataaa ggagacgttg gtaagaaggc agagaatctc attcaaggcc aatttgaagg
      241 atctaaaaca atggaaaagt gctacacaga tgtgactgaa tttgccattc cagcaagtac
      301 tcaaaagctt tacttatcac cagttttaga tggctttaac agcgaaatta tcgcctataa
      361 tctttcaact tcacccaact tagaacaagt acaaacaatg ttggaacagg cattcacaga
      421 gaagcactac gagaatacga ttctccatag tgaccaaggc tggcaatacc gacacgattc
      481 ttatcatcgg ttcctaagag taagggaatt caagcatcta tgtcacgcaa gggaaacagc
      541 caagacaacg gtatgatgga gtccttcttt gggattctga aatcggaaat gttttacggt
      601 tatgagaagt cgtttcagtc gcttaagcaa ttggaacaag ccattataga ctatattgat
      661 tactacaaca ataaacgaat taaggtaaaa ctaaaaggac ttagccttgt gcaatacaga
      721 actaaatcct tcggataaat tatttgtcta actttttggg gtcagtacac ctaaaacttt
      781 gatgatatac gttttcttgt gagaatattt acttcatttt tgcctaaaat tcaatgttta
      841 ctcagtattt ggattatgaa aaatcgaggt ctaaatctag atacattttt tctgaagaca
      901 aatcattttg accaccgagc aagagatttt caaaaaaagc tgttaaaaac tcagaacgtc
      961 gctgtaaaat ctttgcatta tctaatacca aggcatcacg aaaatatttg gaatgttgct
     1021 gaaatggtgt attatcaata tcaaaaccaa actcacgaag atactgaatc aaaaagaccg
     1081 ttactgtccg agtgtttcct tcgcgaaatg gatgaatctg ccagattcct gaaataaaat
     1141 gctggatttg tttaaccaca tccgcctgag ttagtgtcgc atatgcaact tgtttttcct
     1201 gattaaaatc ataatctaag gtcatttgaa tcatggagta atcagagtac acaacacttt
     1261 caccattcaa aacaggttca ttctttgtga tattggtctg acgaaattgc cccaccggaa
     1321 tagagggttc aaatatatct tgaaacaact ccttatgaat agcaagtaag gtcgcaggac
     1381 taaagctaaa gcctcttcga gacaatagtt ctacaatacg tagagaaacc aagtctgcct
     1441 cttccgtact tgcatcaata gtatggtgat aagccgttgc atcctcataa acctgctcat
     1501 aagtcagttc tccccgggac tgtttctcag ccaaagattc catatacgct gatggcacta
     1561 gattgtcaac tttctgcaga ccaaaaccta tccgccataa atcacgcttc gcttcataag
     1621 acaagtttgg attgtcaatg ttgtaagttg attgcataga aatatccttt caattgtttt
     1681 tcttcattac cagtaaatca cgaaattggt tggaaactgg cttaaactat aaaaagtcct
     1741 cacaataggt tctatgatat atatatatat acttcatgta aataataaaa gagttataat
     1801 cagcactact gataaattca ataccgattt cgccatctta aaacttagtc aaacgaatac
     1861 cgttgatttc cagttcatta agtcgttgac ctgtcaagac ttctcgttcc ttcaactgga
     1921 aaagttaagg gggaactaat acaaatcctc tacgcttcta tattcaatga tttcattttt
     1981 gataatattc tttttaaact caaaatgttt taaaggatta tcgattaaca ctaactttgg
     2041 aatatcatct agatttgtga ccaaggataa aataaaatcc gattgaaact ccttgacttt
     2101 ttcaaattct tttgcagtta aacgcacacg ccccttagat tttcggatac cttttacttc
     2161 ggcaaggtaa gaatactctt ggacatctac ctgaaagtca tatccatcac cataaagacg
     2221 ggcatcggtt aactgtccac cttggaattt ttcttcttta tcaaaatgaa ggataaaata
     2281 attctcagcc tccattcccg tttcctgtag acgtttgaat ttagttcgaa ctattggttt
     2341 ttcaacgatg gttatgcctg ttttcttccc ttcactggca agtaacattt taactatttc
     2401 agcataacta tgaacatctt catttccaaa catcatatca attaaatctt tacgaaaacg
     2461 ataaacttca gctttctgcc accaaccttt tcgattattg tcaaaataag gatcaaataa
     2521 atccattcta ttttttacaa ctccagttgt ttcagcaatt cccagagaaa ccacatagcg
     2581 ataaaactcc gacttgctag agcattgaaa ttcttttata aaaagcttgt caaacttggc
     2641 aagaccgtag ccaattaaat ttaacaattc ataatgaggg tgtttggaca tcactttctc
     2701 catcaataga tattgatttc attataccaa aaaacacggc tcatcaccgt gtttctgtgt
     2761 ttatttcacc aacttcttca tctcatcaat acgtgctacg gtcgcatcat acttagcttg
     2821 gtaatctgct tgcttgtcgc gttctttttg gacaacttct ggtttagcgt tggcgacgaa
     2881 gcgttcgttg ctgagttttt tgccaaccat gtcgagttct ttctgccatt tggcaagttc
     2941 tttttccaga cgtgccaatt cttcttcgac attcaagagg tctaccagtg gcaagaagat
     3001 ttcggctcct gtgatgacgc ttgacatagc cagttcaggt gcagggatgg ttgatgcgat
     3061 ttccaagtgt tcaggatttg tgaaacgttt gatgtagttg acattgctgt taaagaaggc
     3121 ttccaagtcg ctatcgcttg tcttaacaag gatagtgata ggcttgcttg gagcaacgtt
     3181 tacttccgca cgcgcattac gaacggcacg gatcaagtct ttaaggcttt ccacaccagt
     3241 gtgagcagca aggtcttcaa aggctgggtt gacagttggg tattctgctg taacgataga
     3301 tccttctgag atttgtccaa agatttcctc tgtcacaaat ggcatgattg ggtgaaggag
     3361 acgaaggatc ttgtccaaag tgtatagtag aacagaacgt gtgatgactt tctcttcttc
     3421 gttatcgcta taaaggactt ccttggtcaa ctcaacatac cagttggcaa attcttccca
     3481 gatgaagttg taaaggatat gaccagccac accaaactcg aacttatcaa agttttcagt
     3541 aacttttgca atggtttcgt tgagattgtg gagaatccag cggtccgtca cattaccagc
     3601 ctcacctgtt gcaacttttg tgacattgtc atgcgccaca tccagcgtca aaccttcatt
     3661 gttcatgagg atatagcgag aaatgttcca aattttgtta ataaagttcc atgaagcatc
     3721 cattttctcg taagagaaac gaacgtcttg accaggagct gagccgtttg acaagaacca
     3781 acgaagacta tctgtaccat atttatcaat aacatccatt gggtcaatgc catttccaag
     3841 agatttagac atcttacgtc cttcttcatc acgaattaga ccatggataa gagcattttt
     3901 aaatgggctc tttcctgtaa attcaattcc ttggaaaatc atgcgtgata cccagaaagg
     3961 aataatatca tagcctgtta cgagtgttga atttggatag tagcgtttaa agtcagtagt
     4021 ttcggtatta ggccagccca tggttgagaa gggccagagg gcagagctga accaagtgtc
     4081 aaggacatct tcgtcctgtt tccagccatc gcccgctggg gcttcctcgc cgacatagat
     4141 ttcgcctgct tcattatacc aagcagggat ttggtgaccc caccagagct gacgggaaat
     4201 cacccagtcg tggacatttt ccatccattg caggaaggtg tcgttgaagc gcggtgggta
     4261 aaattccacc ttgtcatctg tgtcttggtt ggcaatggcg ttcttggcca attggtccat
     4321 cttgacgaac cattgagtag acaagcgtgg ctcaactacg acacctgtcc gttctgagtg
     4381 accgactgaa tggacacgtt tttcgatttt gacaagggca ccgatttctt ccaacttagc
     4441 aacgactgcc ttacgagctt caaaacgatc catgcctgaa aattcaaagg caagctcgtt
     4501 catagttccg tcgtcgttca tgacgttgac ttgtggcaag ttatgacgtt ggccaaccaa
     4561 gaagtcattt ggatcgtggg caggtgtgat tttcacgaca ccagtaccaa acttaggatc
     4621 tgcgtgctca tcaccaacga ttgggattaa tttattagca attggaagga tgacattttt
     4681 accaatcaag tccttgtagc gcgggtcttc tgggttgacc gcaaccgcaa cgtccccaaa
     4741 catggtctca ggacgagttg tagcaacttc aagggcgcgt gaaccatctt ccagcatgta
     4801 attcatgtga tagaaggcac cttcgacgtc cttgtgaata acctcgatat cagaaagggc
     4861 tgtgcgagct gctgggtccc agttgatgat aaactcacca cggtagatcc agcctttctt
     4921 gtaaaggtcc acaaagacct tacgaacagc ttttgacaaa ccttcgtcaa gagtgaaacg
     4981 ctcacgagag tagtctacag agagccccat cttgccccat tgttccttga tagtagtgga
     5041 atattcgtct ttccattccc agactttcgt caagaaagac tcacgaccaa ggtcatagcg
     5101 ggaaatgccc tcaccacgca agcgctcctc taccttagcc tgagtggcaa tccctgcgtg
     5161 gtccatccca ggaagccaaa gggtatcaaa accttgcatg cgtttttgac ggatgataat
     5221 atcttgcaaa gttgtatccc aagcgtgacc aaggtgaagt ttacctgtaa cgtttggtgg
     5281 tggaataacg attgaataag gcttagcctt ttgatcgcct gaaggcttga aaacatcagc
     5341 atcaagccat ttttggtaac gaccagcctc aacctcggct ggattgtatt tagatgaaag
     5401 ttctttagac atgtgtgtgt cctttctcta ttttgtttat tttattttga atttgcttag
     5461 cagcttcttc tgcagacaaa ttcgtattat ttattttaaa gtagtggtgc aactcattcg
     5521 gttgatattg ggaatttaat tgaagtgttt cagcggtctc taaaatttct ctttcagata
     5581 cctcaatatg tcgttttaag ggtttgtgct ttaatcgatt ctccgttcga tttcgacgta
     5641 tgcactcttc aagacttgtt tccaactcaa caaaaagaat ctcttgatga taatcatcca
     5701 acaaattctg aatttgcttt aaatacatca gttgatactg atttgaaaaa tcaattacat
     5761 ctgttaaaat tactgatcgc tgatttcttg cacttgctcc aaggaatgaa aaagtgattc
     5821 cacgaacaaa ttcccacatt tcctctgtat agtcctgata gatttctagt gcaaaatcaa
     5881 tggcttgatg gttataaaat agggtagcat ccgtcagtcg agataattct tgaccaatgg
     5941 tcatttttcc tgatgctgga gcaccaatga tgaaaagatg catcaaatca cctcccactc
     6001 actcttcagc aaggcatatc tcaaatcatc acagcagttg ccttgagcat ctttacggtc
     6061 tcttatgcga gcttcgaggg taaagccaag cttttccgcg actcgttgac tttgaaggtt
     6121 atatccaaag caagttagtt caatcttgtg aagacccaaa tctttaaagg ctaagtcaat
     6181 caaggcacgc gcagcttctg gcacataacc tcgcccccaa tagtctgggt gtaaggtata
     6241 gccgatttcc agcacatcat cttcatggcg atggttgaaa tcgacagagc caacgatctt
     6301 atccgttcct ttgacgacaa tcccgtagcc tgctggatag gcgacctctg gcaaactagc
     6361 atagtcaaag atatcctcag catccgccac agtacggact cgtaaaacga gacgttctgt
     6421 ttcgatttta tctggcagct cagttcttgc catccttctt cctcgctttt ttgatgaaac
     6481 tgcccttcat atctacacgc ttatccagat agcgataaac gcgctgatat ccatctccca
     6541 tgaaataggt tggggcaaac agttgatttt taaaatgtcc cttttcatcc aggagttctg
     6601 gggcaacaag tcgctcaaga atcttggcaa agatgtggca aataccgtct tcctcaacaa
     6661 tcctatctac ccgacaatct aaaacaagtg gacaggcgtc taaaatagga gtctgagttc
     6721 gttcagaaat ttcataatgc actcccaaac gttccaattt ctcctgatga ctgataaaac
     6781 cagcctgctc catcgcaagc atagaagttt catcagaaat attcacagta aatttttgat
     6841 actgtttgat ctgctctgcg gcattctctc tcgcaacgac tccaatcaca acccaatctc
     6901 ctagactata cgaggaacta caggtcgtga tgttatagcc aaaattctga tcttgatatc
     6961 ctaaaataaa aacaggaaaa ccataatata gtttattagt tttaaatgat tgttttataa
     7021 caacctcctt tgactaagac acaaaagaaa agccctgcca tctacatgac agggacgaat
     7081 gtatttatcc gcggtaccac ccaatttcgg gccaagcccg catctttagt ctttaaaata
     7141 aaaagacaga aatatttcat tttttcagtc attagcaacc agttttgaca catttgtgga
     7201 cttctcagcg ccgccacttt ctgtaaaatg tgggattcaa aacacctcta atagctctat
     7261 tgtagcaagt ttttctcgga aatgcaaggc tcaagaaaaa ttacttgaac ttgatgccat
     7321 tttctttcaa tttcttgatg gtagctgggc cgattccttt caaggcaagg agttcttttt
     7381 cagtccagtt tttgaaatct gaagcagact tgattccttc atcatagaaa gtcttggcac
     7441 gatcaagtgg aagtccaccc aagtttgctg caaaatcttc tacagaatta gctacttttt
     7501 gagcttgctc tttggtagct tctactgctt gttcaacttt tttagaaaca gccttaccag
     7561 ctgcgcttgc tgactgttct gcacgcttca cgactttttt tgtctcatct acaaccttag
     7621 tcacagtact tgaaaaggca cctgcgcgac ggaggccatt tcgtaattgt tttttacgat
     7681 tgagtttctt tgacatgata aaatcctttc aataaaaaat ccctgctctg acaaggattt
     7741 aacataaaca ttctatcaag attttagtga aaaatcaaga atctttctcg tttaataatt
     7801 tcgctcacca aacaagcctt ctggcaaatc atggaatccc ttgcctactt tgaagttttc
     7861 aaacttacca agcaagaact gataagcatc caagcgactc tcgtagcgaa tcatggcatc
     7921 tttggcacgc tcgtcctggt cttcttcgta aactttttga ctttccttgt gcgccatgtc
     7981 gttaatcatg atttgggtat tgacccaagc ttcaaattcc ttcataaatt cttgttcgta
     8041 actcattttt ctccttattc taatccacga aaatagtccg tatcaatctc acggtagggc
     8101 tggatatcct gaacatactc caacactcct tggaattctc cgtcttcatc gtgtactgca
     8161 gcataggtga tgtggacaaa cttacctcgc gactcagact tgaaccacat ttcatacttg
     8221 tctttgcttc cctcacgaag cctcttcatg atagttttga ccttgtccaa gtacttaggc
     8281 ggatggcaga gttcgacatt gcgcccgact tgagacggcg tccgtttgaa aatcatctca
     8341 tcagctggcg tattgtcatt gtaatactgg aaaatatctt ctttattgac aaaggtaatc
     8401 tccataggga gatgattgag gatgagattg gcctgctcga ctgaaagata gccattacca
     8461 aaagcctgtt gactatggcg gtccagcaca gcttcctttt ccttaggggt aaaggtaatg
     8521 gtaaaatggc cttctggcgt atctatgact tgttgaactt gaccttctgc cgtatctagc
     8581 tgtacaggct cctctgcaat cttttcctca ataaagctct gtcgttctgg cacccatttc
     8641 tctgacggac ggatgatggc atagccatag gcatcgctct cctccgcaat ctgaagccag
     8701 tcatcctgag taaaagactc aaggagaatc atgaggagga tggactcttc cttgaaaatc
     8761 atactttcaa actctgtcgc aaaagcttca aaagcttcct ttacactgct aattgacact
     8821 tctggtagtg acttgactgt cgttagagct gtttgaaaga gttccctaat ctgatcatcc
     8881 actccccaca taactttggg aggtgaatcg tgtccatagc gctccatgat aggaaagaag
     8941 agttcttcct tacgttggta atggatgtca aattgcccca caagccccat ctgacgcacc
     9001 aagcccttgc gcatctccgc aagcatttcc tcgtcttcca tcaactcata ggtatctaac
     9061 aatctacgaa tgcgaatcaa agctgcacgg agggccaaat tttcttcctt aaagacacga
     9121 actgggtgcc cagggtgttc ggtatctaaa acttcgacac ctttgatagc atttttaaaa
     9181 agattggcat ggacatcaca gagttccata acatcttcaa aagtgacgcc cgaatccgag
     9241 ttcatcagct cgtgctccat aagggaaatc tcgatggctg acacgcccgt aaaggtcgca
     9301 tcaaagcgat cttgaaccga ctcaggagag gcgccattgt gcaattctaa caaaatatcc
     9361 cgtaggatat gaatccattc atctgtcatt agtctaatcc aatcacttcg tagccattcg
     9421 cttccagtgt gcgtacaatc ttgtccatag gagttcctgt tagcttagaa ccctgtttaa
     9481 gtgatacttt acgaccaact gtattgcgca ttaagggatt ggcaaggggt ttaaaaccca
     9541 actccactag aatttccaag acttctggat gcttgtccac cacttctgca acaggaattg
     9601 acacatcgat gatattgtcc atgacgacct ccattgtatg ttctaatact caatgaaaat
     9661 caaagagcaa actaggaagc tagccgcagg ttgctcaaaa cagtgttttg aggttgtgga
     9721 tagaactgac gaagtcagta accataccta cagcaaggtg aagctgacgt ggtttgaaga
     9781 gattttcgaa gagtataaaa tgattttact gcttatatta taccatatgg agagagatta
     9841 aaaaactagc agtggagttc ctgctagttt tctgcgactt ggattaccat ctagataagt
     9901 ttaaagaacc aatccaatat cttgtaaaac agcaattgaa ctgcaaaaga aatgatcatc
     9961 caaaagaatt tcacaatccc aataatcggt ttgataaaaa gaatagcaag aattgtccag
    10021 aaaaatttca ttctctctcc tctggcttaa tgagccaccg agccgtatcc attagcttat
    10081 ctgcaataaa gagttttccc agaccaacaa cgacatggtc atctttcttt atcgttttca
    10141 tcacttttac accttgcacg gtcaaaaagt aattaccata aattttagca aaagctttga
    10201 taggattcat attattctcc tttgatgatt tcagcctctt ttcggattgt ttcaacatct
    10261 tcttgatatt gaacttcact atagttgact agcttggata attctttctg caagctttcc
    10321 cccattggtt tcatagttgc aaaggttaaa ccacctgaaa tgataccacc caagatagga
    10381 ataaatttcc ccattccttt ggccaaccct cccttggtaa gattcacacc aaatattttt
    10441 aagacttttt tcaaaatagg gtaccaaagc gtctttgtta aagctttatt aggcactgtt
    10501 ttcattacct gtttggcaat tgttatacca ccagcacgta gcaaacaaag cagcggttcc
    10561 attcacccct aacattacgc ctagataaag caagagggta ttttgagcat cttcactcaa
    10621 ctcctcacgt gaagcccaaa gatcctcata accataaata taacctaatt cttgggccaa
    10681 tttcagagag aaaccataaa attgagccac ataagctgga atggtaattg ccatagcaag
    10741 ccctccaggt aatcctgcca aaacagaagt cccactcgct aataaaacat tatccctaat
    10801 acaggcatta gccactcgat ctaagatttc ttgagataag agagacgttg gaccttgttc
    10861 caataaggta ggaatgtcct gtggacccaa ttctttggaa aacttatcca ctaaaaattt
    10921 cgaacgatca accttaacaa ctggtagttt taccacttgt tgtaatactt gcatagctaa
    10981 gtcttgttca gccatataca aactccttat ttcttttttg caccttatca tattatattt
    11041 cctacaaaaa aagcattttc taattagata acattaaaaa atacagaacc ccttttttat
    11101 agtaaaataa aacaagaaca ggacaaatcg atcaggacag tcaaatcgat ttctaacaat
    11161 gttttagaag tagaggcgta ctattctagt ttcaatatat tttaaaagaa tatttttcca
    11221 tttcaaattc aacctatttt cctccaccaa aaaagggctc tataatattt gtagtgggta
    11281 aattccctat ggatattatg gagcctattt ttgtgtagaa aaaaagtccc atatgaccta
    11341 taatgaaaag cgacaaaaca actcattaga aagaatcata tggaacaatt acattttatc
    11401 acaaaactgc tcgatattaa agacccaaac atcaagattc tagatatcat caataaagat
    11461 acac
//
LOCUS       DAVBIC010000061        11187 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.061, whole genome shotgun sequence.
ACCESSION   DAVBIC010000061 DAVBIC010000000
VERSION     DAVBIC010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11187)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11187)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11187
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.061"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            complement(<1..947)
                     /locus_tag="VQ664_001850"
     CDS             complement(<1..947)
                     /locus_tag="VQ664_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET2789958.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSILVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQVIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LHMTLLLDSLTFFIAFILVTFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGSIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTI"
     gene            complement(1027..1890)
                     /locus_tag="VQ664_001851"
     CDS             complement(1027..1890)
                     /locus_tag="VQ664_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HET2789959.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFHNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTSLYFELNWILLQGLICQRDASYDMKQDDLDKVADYLFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISRHKRLVLILALNCYQHCLEHSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGFALYQKGQCKEGCKQMQEAMHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(1893..3794)
                     /locus_tag="VQ664_001852"
     CDS             complement(1893..3794)
                     /locus_tag="VQ664_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET2789960.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFNDLRRTERQLR
                     QMELEMGEKSGEDLDKLMSDYDRLSENFRQAGGFTYEADIRAILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETISWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKHSLDRYVGNYSRFVELKEQKLATEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSEKTSGNVVLTVENAAV
                     GYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINCVAT
                     HVLELSENGSTLYLGDYDYYVEKKATAEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSDQV"
     gene            complement(4222..4497)
                     /locus_tag="VQ664_001853"
     CDS             complement(4222..4497)
                     /locus_tag="VQ664_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HET2789961.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
     gene            complement(4603..5442)
                     /locus_tag="VQ664_001854"
     CDS             complement(4603..5442)
                     /locus_tag="VQ664_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HET2789962.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVIVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILSHVEEVKNHTELYIGV
                     STLENLVKGGRIGRVTGLLSSLLNIRVVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            5584..6432
                     /locus_tag="VQ664_001855"
     CDS             5584..6432
                     /locus_tag="VQ664_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HET2789963.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSGWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            complement(6525..7442)
                     /locus_tag="VQ664_001856"
     CDS             complement(6525..7442)
                     /locus_tag="VQ664_001856"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HET2789964.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWS"
     gene            7879..8084
                     /locus_tag="VQ664_001857"
                     /pseudo
     CDS             7879..8084
                     /locus_tag="VQ664_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844775.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            complement(8395..8688)
                     /gene="rpmA"
                     /locus_tag="VQ664_001858"
     CDS             complement(8395..8688)
                     /gene="rpmA"
                     /locus_tag="VQ664_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HET2789965.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(8705..9049)
                     /locus_tag="VQ664_001859"
     CDS             complement(8705..9049)
                     /locus_tag="VQ664_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HET2789966.1"
                     /translation="MIQAVFERAEDGELRGAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENY
                     SEFVQTRVITEN"
     gene            complement(9065..9379)
                     /gene="rplU"
                     /locus_tag="VQ664_001860"
     CDS             complement(9065..9379)
                     /gene="rplU"
                     /locus_tag="VQ664_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HET2789967.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYIEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     misc_feature    complement(9415..9502)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(9597..10196)
                     /locus_tag="VQ664_001861"
     CDS             complement(9597..10196)
                     /locus_tag="VQ664_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HET2789968.1"
                     /translation="MTFCAGYVDAYTFIVRGNTLVAGQAGNVVFLSVELIQNNVSDVR
                     DKLLTLITFIMGVFLLTIYKEKLRIVKKPILSLIPLAILSIIIGFVPQTVDNIYLVQP
                     LAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLAFGDYFRTKHTPFLREGFIFVSLL
                     SSFVLGDVFSAYLTIFYHEKTILGVPIMMSIFYLSMLFA"
     gene            10666..10965
                     /locus_tag="VQ664_001862"
     CDS             10666..10965
                     /locus_tag="VQ664_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HET2789969.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
BASE COUNT         3535 a         2316 c         1863 g         3473 t
ORIGIN      
        1 aaaatcgtca taaacaattc acaaactaaa tttccagaaa aggaaagaaa agttggaagt
       61 ggtaatccca tcataaaaac tccgacacct gtcaaagcca gtaaaatcaa aagattataa
      121 atattagctt taattttact agctagaaga gccccaatga tggaaccaat agcccccata
      181 gttaaaatac ttgcataggc tccttctgac ccgtaaagct gattcgaaaa gggaagtaga
      241 aattcaaaag ctgcaaaaaa gaaattaacg ctggaagcta ccagcaaaag gaagaaaatt
      301 tcttgctgat gccagatata gtgtaaccca tccttgatat ctacaaaaat atctctccca
      361 gtaaaagcct ttttctcttg aacttttgct tcctcttttg gaaggaaagt cactagaata
      421 aaagcaatga aaaaagtcag cgagtctagc agtagcgtca tatggagact tgcaaactgt
      481 aaaacaagga aggaaagaac aggagagcta acacctacaa cctgcaaaac cagctctaag
      541 cgagaattat agatcacaat ctcatctttc tccaccactt cagttatgat agctttattg
      601 gctgtgcgag aaaaggcaaa agcaataacc tgcacaatgt tagcaacaat caaagcgcca
      661 atcatccagc tatcattcct tatgaaagaa atagccagac aaagaatccc acaaacaaga
      721 tctgccgtca ttaaaatctt acgacgagaa aaacggtctg aaataactcc gccaaaggga
      781 ttgacgagaa tagatgtgac gagctcagaa atctgataca ttcctaaaac tgtctgtcct
      841 atagtcccca tagaagccaa ccagacacta tttccataat catagagcat atttcccatt
      901 ttattgatag ccccacggct aatcaactgc actgcatagc gattcatatt aaagctcctc
      961 tcaaattttg aaactattgt atcaaaaccg aaaggagctt tttatttttt cccttatttg
     1021 ggaaaattaa cttttgacaa atttttcgta gtgttcctga taataggcta cttgctctgg
     1081 aagacctaac acatcaaaaa tatgcatggc ctcttgcatc tgcttacagc cttctttaca
     1141 ctgtcctttt tgatataagg caaaaccttt taaataatgg aaaacattac gctcataaag
     1201 cttaatacct ttgtcaataa tcttctctgt ataagcctca aaatagttgg cattataaaa
     1261 agaagaatgc tctaaacaat gctggtaaca attgagggcc aaaatcaaca ctaatctctt
     1321 atggcgacta atctcttggt aaaattcctc cctctccata acttctctac caatccgagt
     1381 gacatagtct acatcgtaga aactatagag gttaccgaaa agaatcaact catacatggt
     1441 ccattcttct gttttgaaga gataatctgc taccttatcc aaatcatcct gcttcatatc
     1501 ataactcgca tctctttgac aaatcagacc ttgtagcaaa atccagttca gctcaaaata
     1561 aagggaagtc gtcgaactct tagacttttc aagttgttct ctttgaagct tttgaaaacc
     1621 tgcaatatcg tttgaatagt aaagtgggat aatctgtgcc atcatagaca catgttcatg
     1681 attatgaaaa ttccttgcct tatccatgaa attttcgatt gttacatgaa tgttatccaa
     1741 aatctcaaag aaacgggaga ctgccaggtc agactcccca agctcaaagc gagataactg
     1801 agaggtagag caggattcgc ctgctgcttc ctttaaagaa taatttccac ttgttcgaaa
     1861 ttcacgaaat acttttccaa gatgttccat ctttacacct gatctgataa ttcttcccac
     1921 tcaagcatag cttcttcctg acgatggctg attttatcca gctcagcctg taattccatg
     1981 agtttgtcgg catcgtttgt ttccaacatt tgttcagaaa tggcttggct ttgactttct
     2041 agctcttcaa tttcagcttc tagactttcg atttgtcgca tgagtttgcg aacttctttt
     2101 tgactttctt tctgggcctg atagtcattg actggacttg cttcctttgc ttgattgcta
     2161 gttgaagctt cctcagtctg actcatttct gctgttgctt tcttctcaac atagtagtcg
     2221 taatctccaa ggtagagagt tgaaccattc tcagacaatt ccaaaacatg agttgccaca
     2281 caattgataa agtaacgatc atgactgaca aaaagcaagg taccatcaaa gtcaatcaag
     2341 gcattttcta gcacttcctt actatcaata tccaagtggt tggtcggctc atccagaatc
     2401 aaaaagttat tgttttccat agacaattta gctaaaagca aacgagcttt ttcgccacca
     2461 gatagcatgc cgactgattt tttaacatca tctcctgaga aaaggaaggc tccaagacgg
     2521 ttgcggattt caacttctgg tgtcaatttg aaatcattcc agagttcatc cagcaccgta
     2581 ttacttggtg tcagcttgct ttgggtttgg tcatagtaac caacctcaac attagcgcca
     2641 aagcgctttt ctcccttgat aaacggaatt tgatccacga ttgatttgat aaaggttgat
     2701 tttccgatac cattgggacc aacgatagca acagcattca tcttacgaag gtctaggtta
     2761 atcggttgtg acaggacttc cccatcatag ccaacagccg cattttcaac agtcaaaaca
     2821 acattgcccg acgttttttc agactggaag gtcatgttgg ctgctttctt gccagcttcc
     2881 ggcttgtcca aacgctccat tttttctagt tgtttacggc gagattgagc acgtttggtc
     2941 gttgaagcac gaactagatt gcgattgaca aagtcttcca gagcagcgat ttccttctgt
     3001 tgcttttcat agttttttgc ctcagtagct agcttttgct ccttcaactc gacaaaacga
     3061 gagtaattcc ccacatagcg atccaaggaa tgcttggtca aatctagcgt aattgtcgca
     3121 accttgtcca agaaataacg gtcgtggctg acgataatga gggcaccgct atagtttacc
     3181 aagtaattct ctagccagga gatggtttca atatccaagt ggttagttgg ctcgtccaag
     3241 accaagagat tgggcttttc aaggagcatt ttagctagag ccaaacgagt attttgacca
     3301 cctgaaagtt cagctatttt catctgccac atagactcgt caaacttgaa tccattcaaa
     3361 atcgctcgaa tatcagcttc ataggtaaag ccacctgctt ggcgaaaatt ctcagataag
     3421 cggtcataat ctgacatcag tttatccaaa tcctcaccag acttttcacc catctccagc
     3481 tccatctgac gcagttgtct ctccgtccga cgcaaatcat taaagacatg aagcatttca
     3541 tcgtagatgg tattttcaga ctcaaaacgg ctatcttggg ctaggtaaga cagagaaata
     3601 tcttttttct tattgatttc tccgctagtt ggctcctctt ctccaactaa aatcttcaaa
     3661 agagtagact tacctgcacc atttttccca acaagagcaa tccgatctcg ttcatcaacc
     3721 tgcaggttga tattatcgaa aagaacctct cctgcaaaag aacgttcaat tttattagct
     3781 tgtaaaataa tcataagagt agtatagcat gtttccctaa ggcattcaag ataatcgtaa
     3841 gtcttttagt acaactttta taacataaaa taaactaaat tatgtatatt ttatattaga
     3901 ttccttcact atcttgttgg attttctaac cagctaatct tgtttcaaat agttatcgca
     3961 caagcctatt atttaattct tttcattatt tacgtacgcg tatagcagat tgaaataaga
     4021 tgagaacaaa tcgattggga aagtaaaatt aatttctata aatgttttag caattgtttc
     4081 gtactatttt agattcagtc tactatgtac aatattttcg gaacattcaa ctttttaact
     4141 ctatttatta ctagatttca taattaaaaa gcctactgac caagctagaa agcttgatac
     4201 aataggcttt ttaaagactg attatttaac agcgtcttta agagctttac cagctttgaa
     4261 tgctggtact ttagaagctg caattgtcat ttctttacca gtttgtgggt tgcgaccttt
     4321 acgttctgca cgctcacgaa cttcaaagtt accaaaaccg atcaattgaa ctttttcacc
     4381 agctgcaaga tagtcagcta ctgctgcaaa tacagcttca actgctgctg ctgagtcttt
     4441 cttagtcaat tctgtagctt ctgctacttt agcgatcaaa tcttgtttgt ttgccatgtt
     4501 aatgattcct ccagataatt tctaattaac aaatataatc atatcctaaa atccctttta
     4561 ggtcaagtta aaaacgctat ttcttccaat tttatttatt ttttaggagt ggtaacgtat
     4621 caaaatagcc caagcgttct cacccgtgtg agtttgaata atggaacccg tttccaaaac
     4681 agaaattggc ttttcaacat aagcttgtaa gctttctttc atctcttttg cccaatcatc
     4741 actaccagaa tatgaaattc caatctctgc tacagcacgt tcagaaagcg atgttatcaa
     4801 ctcatctaac cattttttaa atgttttagt tccacgacct ttaaccattg gctgcaattc
     4861 atggtctttc atttgcatga caacacggat attgagaagg gagctcaaca agccagttac
     4921 acggccaatt cgtccacctt tgacaagatt ttccaaagtt gaaacaccaa tataaagctc
     4981 tgtatggttt ttaacctctt ctacatgaga taaaattgcc tccatatctt taccttcttg
     5041 agctaacttc gcagcctcaa caacttggaa tttcagggct tggtcagtga aggaactatc
     5101 aacaacaatc acatctgcag tagataggct agcaccttgg cgtgctgctt ctaccgtacc
     5161 cgaaagagca tgggacatat gaatagcaag aatctggcca ccatctttgc ataggtcttc
     5221 aaaaatctca gcaaagacac ctacaggtgg ctgacttgtt ttcggaagat tcttactttc
     5281 ttgcatcaac tgaagaaatt taccttcttc tttcaaatcc gcatcagaat aaacaacatt
     5341 atcaatcatt acagataatg gaacaattgt aatatctaat tgctttacta gttcaggttc
     5401 aatagtaaca gatgaatcgg ttacaatctt aatttttgtc atagtatcaa tctttctatt
     5461 ttaggattca gattggtttc cttacttcta attatatcaa aaaaaagatt aaaaatccta
     5521 atggagtcaa tcaaattttc cgtaaaattt gatataatca acttataaga aaagaggtgt
     5581 cctatgatta aaaaaattta ccccattttt accattttac taggtgctgc tatttatgct
     5641 tttggactga cttattttgt agttccccat catctctttg aaggaggggc gacaggtatt
     5701 accctcatca cattttatct ttttaaaatc cctgtttccc tcatgaacct gctgattaat
     5761 attccccttt tcatcctagc ttggaagatc tttggagcca aatccctcta ttctagttta
     5821 ctaggaacct tagctttgtc cggctggtta gctttttttg agcatattcc ccttcatatt
     5881 gatcttcaag gtgatttact aataacagcc cttatagcgg gaatcctatt gggaattggc
     5941 cttggaatta tttttaatgc tggaggtaca actggcggaa ctgatattct agctcgtatt
     6001 ctcaacaaat acactcatat atccatagga aaactgctct ttatcttaga tttttgtatt
     6061 ctcatgttga ttctcctaat cttcaaggat ttgagattgg tttcctacac gcttttgttt
     6121 gattttattg tttctcgtgt tattgatttg attggtgaag gaggatatgc cggcaaaggc
     6181 tttatgatta tcacaaaacg tcctgaccaa cttgctaagg cgattaatga tgacctcgga
     6241 agaggtgtta cttttatttc tggtcaaggc tactatagta aagaaaattt gaaaatcatc
     6301 tactgtattg tcggaagaaa tgaaattgtg aaaacgaagg aaatgattca tcgaatcgat
     6361 cctcaagcct ttataactat tacagaagcc catgaaatcc taggagaagg cttcaccttt
     6421 gaaaaagaat aaaaagaggt aatgtcgtga cctcaaaagt tagactaaat catctatctt
     6481 ttgggttaca gacaacctct tttttgtttt atttactcaa gctcttaaga ccaattccga
     6541 gttacttctt catcagcctt taactgatcc actaattggt caactgagtc aaatttggtc
     6601 atatcacgaa tgcgatcaag ccaataaacc atgacggttt ccccataaat atcttgatta
     6661 aaatcaaaaa tattgacttc aaaacgtgct tcttctccat caaaggtcac atttttcccg
     6721 acactagcca tagcacgata cttctgtctt tgaatctcaa catcaacgac ataaacgcca
     6781 tctgctggca tataagtacg gtctaaaagc actaaattcg ctgtcggata accaattgta
     6841 cgaccacgag cattaccatg aaccaccata cctcttgatg gaagcggtgc ccccaaaagt
     6901 tttcctgctt ctttcacatt tccatctaaa atagcttgac ggatacgagt tgaactaatc
     6961 tttcctttct catcttctac aggtggaaca atgataactt ctccatcaaa gtaatccttt
     7021 aaatcttctg ctgttttttt gtcagaacca aatgtataat caaaacctgc aacaataatt
     7081 ttggcattca tagccttgat ataagttgca aagaattctt gtgcagtgag actagcgaat
     7141 tgactactaa aatcaaggag atataattct tctacacctt cgcgctttaa ttttctttca
     7201 cgttcagcag ggttcaaaat atgcaaaaac aaatccggat gataaggctc taaagcgatc
     7261 tttggagatt cattaaaggt cataacgacg ataggtaata aatcctttct cgcagccttg
     7321 ttggcaacac gaaataattc ttgatgcccc ttatgtatgc catcaaaata gccgagaaca
     7381 acgactgaat cagatggtgt gccaatatct ttttggtttt ttataggaat agtaataatc
     7441 ataaaataat tatatcatag cgatagctat ttctggaaca gaaaatctga aatgttgttt
     7501 ttttcacatg aagtgtacct gttttcaaaa agcactttat tctatcgttg cttaactatg
     7561 aactttgcaa tattcttctc aaaaacttgt aggacatctt caaaattttg caaggagtga
     7621 ttagacttgt tcggtaacca taaagtgtca tactatgtta tgtatgaaaa agcaatgcaa
     7681 ctaactcctg agaactttaa attactaatt ggtgccgaaa aggtagaatt tagaatcgag
     7741 gtacacctat ggctgtaaaa tttacaaaat gagacaactt gggcaagatg tttgaagaat
     7801 ttcctaaact ccctgatttg aagcaagtca ctttccctga tgacaaagaa aaaagccaaa
     7861 acagcaaaga aaaactagat gactgctttc caacaactcc catctagtgt gcttcagact
     7921 gggctatttt tctctccatc tgttagcttg gattctcaga ccgtttcagc taaagaatat
     7981 cttttccctt atcagaagga acggctcaaa ccattcagac aagtgaaggg acgacaagcc
     8041 aatatttgaa accagatagc agttcttata gtcaattgaa ataaaatctg aagaaatcga
     8101 gtaggaaact catatcaatt tttaacagtg ttctattcca gattcatact caatgaaaat
     8161 taaagtgcaa actaggaagt tagccgcagg ctgtacttga gtacggcaag gtgaaactga
     8221 cgtggtttga atttgatttt cgaagagtat caatccacta tacatattaa aaagtatgga
     8281 tatcaaaaca aaaaaacagg ctctccgaaa actcggaaag ccttatttta agctgtttct
     8341 agcttcctca cctttacatt tcaaggttcg ggataaaagg ttcaatggac ctttttattt
     8401 agcgattggg taaacagaaa cttgtttttt atcgcgtcct ttacgttcaa agcgtactac
     8461 gccttcaact ttagcgaaca aagtatcgtc tccaccacga ccaacgttta cacctggata
     8521 gatgtgtgta ccacgttgac ggtaaaggat tgatccacct gttacagttt gtccgtcagc
     8581 tgctttagct ccaagacgtt ttgcttgtga atcacgtccg tttgatgtag aacctccacc
     8641 ttttttgtgg gcgaaaagtt gcaagttgtt aagagtcatt tttaacataa tgttttcctc
     8701 cgtgttagtt ttctgtgata actctggttt ggacgaactc agaatagttc tccgataagt
     8761 ttgccatacc taagaaaaat gattcaaaga ataactgggt catttctctc tggtgtgaag
     8821 gaagatcttt tggtatttca accatcagat agccaccttc atcttcgttt aattctagga
     8881 ttggttcata gcctgcaaat ttctcaatag aattgataaa gttaatggca agcgtagaaa
     8941 ccgatgcaca cacgacatct aagccgtatt cgccactctc ggcgtgtcca gtaatttccg
     9001 cacccctcag ctcgccatct tcggctctct caaagactgc ttgtatcatg tgttctcctt
     9061 aaaattaagc gttaattgcg ttgatgacaa cttttgtata tggttgacgg tgaccttgtt
     9121 tacggtggct acctttttta ggtttgtact tgtaagtaac aactttcttt tgttttcctt
     9181 gtttttcaac agttccaact acagtagctc cagcaacaag tggagttccg acaacagtgt
     9241 tttcaccacc aacaagaaca acttcgttaa aagtaacttc ttgaccagct tcaacgttca
     9301 atttttcaat gtaaactgct tgaccaactt caactttaac ttgttttccg ccagttttga
     9361 taattgcgta tgtgctcatt atgcacctcc tatgattttt atgggtttcc ccgatttttt
     9421 gtgaagactc gcctagcatc gtgggacaaa ccacttaaac ttgaataatc aagcaacgat
     9481 gttcgtgcgg ttgcacagga tcgtgcatag tcaactcttc aagtatagca tatctcctat
     9541 tttcttacaa gtaataacac ctaaaatcaa gctttttctt ttactttttt ctgccactag
     9601 gcaaaaagca tactgagata aaaaatgctc atcataatag gaacaccaag aatggtcttt
     9661 tcatgataga aaatcgtcaa ataggctgaa aagacatcgc caaggacaaa actactaagc
     9721 aggctaacaa atatgaaccc ttcacgcaaa aaaggagtgt gcttagttcg gaaataatct
     9781 ccaaaagcta gcattgttcg tttgatattc cctgtcataa aggcattatt gtaggcaata
     9841 cccgaaacct caccaaaagc agttgtcacc agtcccatac agaaggccaa gggctgcact
     9901 agatagatat tatctacagt ttgtggcaca aaaccaataa ttattgatag gattgctaaa
     9961 ggaatcaagg acagaatagg ttttttcaca attctcaatt tttccttata aatcgttaat
    10021 aaaaagactc ccattataaa cgttattaag gttaaaagct tatccctaac atccgaaaca
    10081 ttattttgta ttagctctac cgaaagaaag acaacatttc cagcttgtcc agctacaagg
    10141 gtattccctc gaacaataaa agtgtaagca tccacatatc cagcacaaaa tgtcaaaaaa
    10201 gtgctaacct tttagactga cgtgatattt ttcttatagg taataacctc attttccctc
    10261 ccattgtatt ttctcttaga aatattgtac catttctttc taaaaaatcg tagactacca
    10321 tttagatttt actattagca taaaaataat aatagacaac tatttatcca aaaatagata
    10381 gaggtaacat gtttgcaaac aaagcatacg aacctttagt aaaatcattt ccatgaaact
    10441 agaatagagc ccctcttagc aaaaatcatt attttaattt atttctaatc actccttgac
    10501 ataaataact ctcaccaata aaagactatg tcttaaaaaa atggtataat aaaatcaata
    10561 cctgggcttg atggctatgc tactaataac aattaggaga gaaaatcagg cacttgttaa
    10621 caacaaggat tatccccttg agatgaaagg aactttagaa atcttatgat gaacatgcaa
    10681 aacatgatgc gtcaagcaca aaaacttcaa aaacaaatgg aacaaagcca agctgaactt
    10741 gctgctatgc aatttgttgg caaatctgct caagatcttg tccaagcgac cttaactggc
    10801 gataagaaag ttgtcagcat tgatttcaat ccagctgtcg ttgacccaga ggaccttgag
    10861 actctttctg atatgaccgt tcaagccatc aactctgctc ttgaacaaat cgatgaaact
    10921 actaagaaaa aactgggtgc tttcgctggg aaattgccat tctaaaaaca aggagctaga
    10981 acaatacttg tcgataacaa aggctaagaa aggtgcaaaa attataaaaa acgcatagta
    11041 tcaagcaacc taaaactttg ggctctataa tatttgtagt gggtaaatcc actatagata
    11101 ttatggagcc tattttattg tagaaaaaaa tcccataaga tctataatga aaagcgacca
    11161 aacaactcat tagaaagatt catatgg
//
LOCUS       DAVBIC010000062        10988 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.062, whole genome shotgun sequence.
ACCESSION   DAVBIC010000062 DAVBIC010000000
VERSION     DAVBIC010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10988)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10988)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10988
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.062"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            135..2315
                     /locus_tag="VQ664_001863"
     CDS             135..2315
                     /locus_tag="VQ664_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HET2789970.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFTPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDTSQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEA
                     QQNTVHFKNLTEEVYSVADGQVVGLEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVAAGDLLVTADL
                     DAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            2367..3182
                     /locus_tag="VQ664_001864"
     CDS             2367..3182
                     /locus_tag="VQ664_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HET2789971.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLLEQGKNYYWTWAYNHIGYDRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETLVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAMLNWK"
     gene            3322..4665
                     /locus_tag="VQ664_001865"
     CDS             3322..4665
                     /locus_tag="VQ664_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET2789972.1"
                     /translation="MSFTKFQFKNYIREALKELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLASNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLEIVDKIAGSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYQLTQLMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
     gene            5042..6232
                     /locus_tag="VQ664_001866"
     CDS             5042..6232
                     /locus_tag="VQ664_001866"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HET2789973.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVIDK
                     VIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            6785..7720
                     /locus_tag="VQ664_001867"
     CDS             6785..7720
                     /locus_tag="VQ664_001867"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HET2789974.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            7754..8791
                     /locus_tag="VQ664_001868"
     CDS             7754..8791
                     /locus_tag="VQ664_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HET2789975.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQVLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNSSPTTKLIIFAEGKLDSKRRLVKLLKRDAKVFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKANSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            8964..9569
                     /locus_tag="VQ664_001869"
     CDS             8964..9569
                     /locus_tag="VQ664_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HET2789976.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHTLFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            9725..10255
                     /locus_tag="VQ664_001870"
     CDS             9725..10255
                     /locus_tag="VQ664_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HET2789977.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKEQRHFVIRQK"
     gene            10276..>10988
                     /gene="rlmN"
                     /locus_tag="VQ664_001871"
     CDS             10276..>10988
                     /gene="rlmN"
                     /locus_tag="VQ664_001871"
                     /EC_number="2.1.1.192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HET2789978.1"
                     /translation="MKPSIHSLAHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQGIVQESADGTVKYLFELPDGMLIETVLMCQHYGLS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFDERGQDERISHIVVM
                     GIGEPFDNYNNVLNFFRTINDDKGMAIGARHITVSISGLAHKIRDFADEGVQVNLAVS
                     LHAPNNELRSSIMKINRAFP"
BASE COUNT         3342 a         2017 c         2394 g         3235 t
ORIGIN      
        1 agaaattttt tagaaaaaag tgtaattttt ttataaaagc ctttacaaaa aaaattaaag
       61 tggtataatt aaatcataga aggtgcaaac gttttcgtaa aacgtttgcc taaataaaaa
      121 taaaggagat ttgaatgatg aaagatacat tcaaaaatgt cttgtctttc gaattttggc
      181 aaaaattcgg taaggctttg atggtagtta tcgcggttat gccggctgct ggtttgatga
      241 tttcaatcgg taagtctatc gtgatgatta acccaacctt tacaccactt gtcatcacag
      301 gtggaattct tgagcaaatc ggttgggggg ttatcggtaa ccttcacatt ttgtttgccc
      361 tagccattgg aggaagctgg gctaaagaac gtgctggtgg tgctttcgcc gctggtcttg
      421 ccttcatctt gattaaccgt atcactggta caatttttgg tgtatcaggc gatatgttga
      481 aaaatccaga tgctatggta actactttct ttggtggttc aatcaaagtt gctgattact
      541 ttatcagtgt tcttgaagct ccagccttga acatgggggt attcgtaggg attatctcag
      601 gttttgtagg ggcaactgct tacaacaaat actacaactt ccgtaaactt cctgatgcac
      661 tttcattctt caacgggaaa cgtttcgtac catttgtagt tattcttcgt tcagcaatcg
      721 ctgcaattct acttgctgct ttctggccag tagttcaaac aggtatcaat aacttcggta
      781 tctggattgc caactcacaa gaaactgctc caattcttgc accattcttg tatggtactt
      841 tggaacgttt gctcttgcca tttggtcttc accacatgtt gactatccca atgaactaca
      901 cagctcttgg tggtacttat gacattttaa ctggtgcagc taaaggtact caagtattcg
      961 gtcaagaccc actatggctt gcatgggtaa cagaccttgt aaaccttaaa ggtactgata
     1021 ctagtcaata tcaacacttg ttagatacag tacatccagc tcgtttcaaa gttggacaaa
     1081 tgatcggttc attcggtatc ttgatgggtg tgattgttgc tatctaccgt aatgttgatg
     1141 ctgacaagaa acataaatac aaaggtatga tgattgcaac agctcttgca acattcttga
     1201 caggggttac tgaaccaatc gaatacatgt tcatgttcat cgcaacacct atgtatcttg
     1261 tttactcact tgttcaaggt gctgccttcg ctatggctga cgtcgtaaac ctacgtatgc
     1321 actcattcgg ttcaatcgag ttcttgactc gtacacctat tgcaatcagt gctggtattg
     1381 gtatggatat cgttaacttc gtttgggtaa ctgttctctt tgctgtaatc atgtacttta
     1441 tcgcaaactt catgattcaa aaattcaact acgcaactcc agggcgcaac ggaaactacg
     1501 aaactgctga aggttcagaa gaaaccagca gcgaagtgaa agttgcagca ggctctcaag
     1561 ctgtaaacat tatcaacctt cttggtggac gtgtaaacat cgttgatgtt gatgcatgta
     1621 tgactcgtct tcgtgtaact gttaaagatg cagataaagt aggaaatgca gagcaatgga
     1681 aagcagaagg agctatgggt cttgtgatga aaggacaagg ggttcaagct atctacggtc
     1741 caaaagctga cattttgaaa tctgatatcc aagatatcct tgattcaggt gaaatcattc
     1801 ctgaaactct tccaagccaa atgactgaag cacaacaaaa cactgttcac ttcaaaaatc
     1861 ttactgagga agtttactca gtagcagacg gtcaagttgt tggtttggaa caagtaaagg
     1921 atccagtatt tgctcaaaaa atgatgggtg atggatttgc agtagaacct gcaaatggaa
     1981 acattgtatc tccagtttca ggtactgtgt caagcatctt cccaacaaaa catgcttttg
     2041 gtattgtgac ggaagcaggt cttgaagtat tggttcacat tggtttggac acagtaagtc
     2101 ttgaaggtaa accatttaca gttcatgttg ctgaaggaca aaaagttgca gcaggagatc
     2161 tccttgtcac agctgacttg gatgctatcc gtgcagcagg acgtgaaact tcaacagtag
     2221 ttgtcttcac aaatggtgat gcaattaaat cagttaaatt agaaaaaaca ggttctcttg
     2281 cagctaaaac agcagttgct aaagtagaat tgtaatatac ttgaggttgg aagctgtatt
     2341 ccaacctctt attttgggag aaaagaatga aatttttaac actcaatact cacagttgga
     2401 tggagaaaga agcagaggaa aaattccaga ttttgcttga agatattctt gaaaaggact
     2461 atgatttgat ttgtttccaa gaaatcaatc aggagatgac ctcgtcagag gtggaggtta
     2521 atgaccttta tcaagctttg ccagcagctg agcctattca ccaagaccat tatgttagac
     2581 tcttggttga aaagttgtta gagcaaggga aaaattacta ctggacctgg gcttataacc
     2641 atatcggcta tgaccgctac cacgaaggtg tggctatctt gtctaaaaca cctattgaag
     2701 ccagagaaat tttggtttca gatgtggatg atccaacaga ctatcatact cgccgtgttg
     2761 ccctagctga aactttagtc gatggcaagg agctagcagt tgccagtgtt catctctctt
     2821 ggtgggataa aggtttccaa gaagaatggg cacgatttga ggctgtcttg aaaaaattga
     2881 acaagccact tttactagct ggagatttta acaacccagc aggtcaggaa ggttaccaag
     2941 ctattttagc tagtccatta ggcttacaag acgcatttga agttgctcaa gagaaaagtg
     3001 gtagctatac tgttccgcct gaaattgatg gctggaaagg gaacactgaa ccccttcgaa
     3061 tcgattatgt ctttactacc aaagagttag cggtggaaaa tttacatgtc gtatttgatg
     3121 gtaacaagag tccacaagtg agtgatcact atggcttgaa tgctatgtta aactggaaat
     3181 aataactgaa aagaggttgg aactataaaa ttccagcctt ttcttactag agaagctact
     3241 ggaaatagcc taaataagtg agactactgt aatggaataa aatatggtat aattgataag
     3301 atagatagaa tcgaggatgt tatgtcattt acgaaatttc aatttaaaaa ctatattaga
     3361 gaagccttga aggagttaaa atttacaact ccaacagagg tgcaagataa gttgattcct
     3421 attgttttgg caggtcgtga cctagtagga gaatcaaaaa caggttcagg taagactcat
     3481 actttcttgt taccgatttt ccagcaatta gatgaagcta gcgatagtgt acaagcagtg
     3541 attactgcac cgagtcgtga gttggctact caaatttacc aagtagcgcg tcagatttca
     3601 gctcactcag atgtcgaagt tcgtgtggtt aattatgtgg gtggtacgga taaggctcgc
     3661 cagattgaga aattggcaag caatcagcct catattgtta ttggaacacc aggccgtatc
     3721 tacgacttgg ttaaatctgg tgatttagct attcataaag ccaagacatt tgttgttgat
     3781 gaagcagata tgaccttgga tatgggattc ttggaaattg ttgataagat tgctggcagt
     3841 cttccaaaag acttgcaatt catggtcttc tcagcgacta tcccacaaaa actgcaacca
     3901 ttcttgaaaa aatacttatc aaatcctgtt atggagaaaa ttaagactaa aacggttatt
     3961 tctgacacca ttgataattg gttgatttcg accaagggac atgataagaa tgctcaaatt
     4021 taccaattga ctcagttgat gcagccgtat ttggcaatga tttttgttaa cactaaaacg
     4081 cgtgctgatg aattgcattc atatctgact gctcaaggct tgaaggttgc aaaaatccat
     4141 ggagatattg cccctcgtga acgcaagcga atcatgaatc aggtgcaaaa tctggatttt
     4201 gagtatattg tcgcaacaga tttagcagcg cgtgggattg acattgaagg tgtcagccat
     4261 gtcatcaatg atgccattcc gcaagactta tctttttttg ttcaccgtgt tggtcgtact
     4321 ggacgaaatg gcctaccagg tacagctatt accctttatc agccaagtga tgactcggat
     4381 atccgtgagt tggagaaatt gggaatcaag tttagtccta agatggtcaa agatggggaa
     4441 tttcaagata cctatgaccg tgatcgtcgt gccaaccgtg agaaaaaaca agataaactt
     4501 gatatcgaaa tgattggttt ggttaaaaag aaaaagaaaa aagtcaaacc gggttataag
     4561 aagaaaattc aatgggcggt tgatgaaaag cgccgtaaaa ctaagcgtgc tgaaaatcgc
     4621 gctcgcggtc gtgcagagcg taaagctaaa cgccaaacat tttaatagaa attgttggag
     4681 tactgagctc caactttttt atttatgaga acgaactatc taaaccgaaa cactacatta
     4741 aagactgcaa attgcgatta aaaatggtat aatgataaag ttatatagtc ccgataagat
     4801 ggtaggtatt tattacgaag agttttccta tcagtagttt gcaattcgca aagaatgacg
     4861 gcttcgaggt cgctcgtctt tctacggttg ccgccatact gcggtcaccc tatgcgcctt
     4921 actagcttca gaaataaaaa agtatcgttt ttatttctga agctagtaac tcttagataa
     4981 tggaaattcc tatcagtact ttgtaactct ataacaatat tttttaaggg gggacatttt
     5041 tatgtcagaa cgtaaattat tcacgtctga atctgtatct gaggggcatc cggataagat
     5101 tgcagaccaa atttcagatg cgattttgga tgctatttta gcaaaggatc cagaggcgca
     5161 cgttgctgct gaaacagctg tatatactgg ttctgtccac gtttttggtg aaatttctac
     5221 aaatgcctat gtggatatta accgtgtggt tcgtgatacc attgcagaga ttggttatac
     5281 caatacagaa tatggatttt ctgctgagac ggtgggagta cacccatctt tggtggaaca
     5341 atctcctgac atcgctcaag gtgttaacga agccttggag gttcgtggaa atgctgatca
     5401 agatccactg gacttgattg gagcaggtga ccaagggctc atgtttggat ttgcagtaga
     5461 tgaaacagaa gagctcatgc cattgccaat tgcactcagt cataaattgg ttcgtcgtct
     5521 ggcagaactt cgtaagtctg gagaaattag ctatctccgt ccagatgcaa aatcacaagt
     5581 tacagttgag tacgatgaaa atgaccgtcc ggtacgtgta gatacagtcg ttatttctac
     5641 tcagcatgat ccagaggcca ctaatgaaca aatccatcaa gatgtgattg acaaggtcat
     5701 caaagaagtt attccatctt cttatcttga tgataagaca aaattcttta tcaatccgac
     5761 aggtcgtttt gtaatcggtg gtcctcaagg ggactcaggt ttgactggtc gtaagattat
     5821 tgtagatact tatggtggct actctcgtca tggtggtggt gccttctctg gtaaagatgc
     5881 gactaaggtg gatcgttcag cctcttatgc ggctcgctat attgccaaga atatcgttgc
     5941 agcaggcctt gctaagaagg cagaagtgca gttggcctat gctatcggtg ttgcgcaacc
     6001 tgtttctgtt cgtatcgata ctttcggtac aggaacagta gctgaaagtc aacttgaaaa
     6061 agcggctcgt caaatctttg accttcgccc tgcagggatt atccaaatgc tggacctcaa
     6121 gcgtccaatt taccgtcaaa catcggctta cggtcacatg ggacgtacag atattgatct
     6181 tccatgggaa cgtttggata aggtagatgc tttgaaagaa gcagtaaaat aagattttaa
     6241 gaggggaacg tcctctcttt tttatagttt ttaactatac tgggatactg ttctgaaaat
     6301 ccattttgcg aaagtagaga tttacatgta taatggattg aaactagaat agtacacctc
     6361 aacttctaaa acattgttag aaatcgattt gactgtcctg atcgatttct cctgttcttg
     6421 tttcatttta ctatatttct ttaaaaatga taaaggttga gatttctcct cgtaatagat
     6481 aatcatgggg atatttcaat ccaaagtttt attcgttatc acttgactat tgcaaggttt
     6541 tctagagcaa cagagtcatg gaatggactc atggttgaga tttctccttg ttgcttggac
     6601 ttcattcaaa agtctgttac ccaagccttg ttcaaacttc caatacacta gctgtttcca
     6661 tagcatgact tctgtactag actttctttt ccgaataaat agatagaacc acagaatcta
     6721 gtaaacctag aattaaaatt atggtataat attagcaata aaagaaatct ggaggattag
     6781 aatcatggta tcaacgaaaa cacaaattgc tggttttgag tttgacaatt gcttgatgaa
     6841 tgcagcaggt gtggcttgta tgacgataga ggagttagaa gaggtcaaaa actcagcggc
     6901 aggaaccttt gttactaaga cagcgacctt ggacttccgt caggggaatc ctgagccacg
     6961 ctaccaagat gttccacttg gttccatcaa ctctatgggc ttgccaaata atggcttaga
     7021 ctattatttg gattatcttt tagatttgca ggaaaaagag tcgaaccgaa ctttcttctt
     7081 atctctggtc ggcatgtctc cagaggaaac ccatactatt ttgaaaaaag tccaagagag
     7141 tgattttcgt ggtctgactg agctaaatct ttcctgtcca aatgttccag gtaaacctca
     7201 gattgcctat gattttgaga caacagaccg gattttggca gaagtgtttg cttacttcac
     7261 caaacctctt ggaattaaat tgccacctta ttttgatatt gttcactttg accaagcggc
     7321 agctattttc aacaaatatc cgctcaagtt tgtcaactgt gttaactcta tcggaaacgg
     7381 cctctatata gaagacgaat ctgtcgttat tcggcctaag aatggttttg gtggaattgg
     7441 tggagaatac atcaaaccga ctgctctagc caatgttcac gccttttatc aacgtttaaa
     7501 tcctcaaatc caaattatcg gaacaggtgg cgttctgact ggtcgagatg cctttgaaca
     7561 catcctctgt ggagcaagta tggtgcaggt gggaacgacc cttcacaaag aaggcgtcag
     7621 tgcttttgac cgcattacca atgaactgaa agcaatcatg gtggaaaaag gctacgagag
     7681 cttagaagat ttccgtggga aattgcgcta tattgactaa attaaatcga aaaatctgaa
     7741 gaaaggagag acgatgctag ccattgaaga aagtcagaag ttgactttat caaatttacc
     7801 gagcctgagc ctatttacag ggacagatca gggtcagttt gaagtgatga agagtcaagt
     7861 gttgaaacag attgggtatg attctgctga cctcaacttt gcctactttg atatgaaaga
     7921 agtagtttac aaggatgtgg aactggagtt ggtcagcctt cctttctttg cggatgagaa
     7981 aatcgtgata ttagattatt ttatggatat cacgactgct aagaaacgct ttttgacaga
     8041 tgatgagctt aagtcatttg aggaatacct tgacaattct tctccaacaa ccaagttgat
     8101 aatctttgca gaaggaaagc tggatagcaa aagacggtta gtcaaattac ttaagcgtga
     8161 tgccaaggtc ttcgatgcag tagaagtaaa agaacaagaa ttgcgccagt atttccaaaa
     8221 gtggagtcag aaacaaggtc tgcagtttac caatcattct tttgaaaatc tcctcatcaa
     8281 gtcggggttt caatttagcg aaatccagaa aaatcttctc tttttacagt cctataaggc
     8341 gaattctgtt attgaggaag aggatattgt taacgcaatt cccaagacct tgcaggacaa
     8401 tatttttgat ttaactcagt ttattctgac taaaaagatg gatcaggcgc gcgatttggt
     8461 gagagacttg accttgcaag gggaagatga aatcaaactg attgcagtca tgctgggaca
     8521 atttcggact tttactcagg tgaagatttt ggcggagtct ggccaaacag aatcgcagat
     8581 tgcaagtagt ttaggtagtt atctgggacg taacccaaat ccttatcaaa tcaagtttgc
     8641 attaagagat tcgagaggac tttctttgag ctttctgaag caagctattt cctatttgat
     8701 tgagacagac tatcagatta agacaggtct ttatgaaaaa ggtttccttt ttgaaaaggc
     8761 actcttacag attgctagtc aggtcaattg acatttgttg aaactacaac ccgcgtcagg
     8821 attatcttgt cgtgggtttc ttgctgattt gcttatttta ttagaaagta tgtcagtgat
     8881 ttccttatct ataagcaaaa aacttgaaaa aagtgaatgt ttgcgttatc attttcatat
     8941 agaaagaaaa agaggtatta cagatggcta ttatcttacc agaacttcca tatgcatacg
     9001 acgctttgga accatacatc gatgcggaaa caatgcattt gcaccatgac aaacaccatc
     9061 aaacttatgt caacaatgcc aatgcagctt tagaaaaaca ccctgaaatc ggtgaagacc
     9121 ttgaagcctt gcttgctgat gtagaatcta tcccagctga tatccgtcaa gcacttatca
     9181 acaatggtgg cggacacttg aaccacactc ttttctggga attgatgact cccgagaaaa
     9241 cagctccttc agcagaactg gcagcagcaa tcgatgcaac atttggttca tttgaagaat
     9301 tccaagcagc cttcactgca gcagcaacaa ctcgttttgg ttcaggttgg gcatggttgg
     9361 ttgtcaacaa agaagggaaa cttgaagtga cttcaacagc aaaccaagac acaccaatct
     9421 cagaaggtaa aaaaccaatc ttgggcttgg acgtttggga acatgcttac tacgtgaaat
     9481 accgcaacgt gcgtcctgac tacatcaaag ctttcttttc agtaatcaac tggaataaag
     9541 tagatgaatt gtacgcagct gctaaataat gatagttgga gggaagaatt gttcttctct
     9601 ttttaggtta taagattctg gtctgacaaa atcgtcagac ttttttcatt tttatgagaa
     9661 acgtgctaac tgctagaaat tatggtagaa taaagtatta agtaatcgtg gaaaaaggat
     9721 atctatgcga aaagaaattg cacctgaatt atacaactat aacaagtttc ctggtccgga
     9781 gttccattta cacggggata aggtcgaaac ggaagggata gctttttcct tggttgaaaa
     9841 tatcaaggat gcctttgatg tgacgacttt taatcagcgt ttttcagaag tcttaaccaa
     9901 gtttgattat atcgtggggg actggagcaa cgaacagctt cgcctacgag gtttttacaa
     9961 ggatgaccga acagaagaaa aacttgaaaa aatcagtcgt ttacaagact accttttaga
    10021 gtattgtagt tatggttgtg cctattttgt cttagaaaat gaagccccta agcgagcatc
    10081 atttgacaag aaaatgcgta agacggaaga agaaacacct tctagaaaag gaaagaaacc
    10141 gactcaaact aaacgaaagt cgaatgcaga taagaaaaat agacgtcgtc agaaagacca
    10201 gcattctcag aaagaggaca aggaacaacg tcattttgtc attcgtcaga agtgagtaga
    10261 gaataaggag aagaaatgaa accctcaatt catagtttgg cacatcaaac catgcaggaa
    10321 tgggtattgg agcagggaga aaagaaattc cgtgcagatc aaatctggga atggctctac
    10381 cgtaaacgtg tgcagtcatt tgaagaaatg accaaccttt ccaaggattt gattgctaag
    10441 ctcaatgacc agtttgtggt caatcccttg aaacaaggta ttgtgcaaga gtctgctgat
    10501 ggtacagtca aatatctctt tgaattgcct gacggtatgt taattgagac tgtactcatg
    10561 tgtcaacact atggtttatc tgtctgtgtg accactcagg tcggctgtaa tatcggttgt
    10621 accttctgtg cctctggttt gattaagaag cagcgtgacc tcaataacgg tgaaatcgta
    10681 gcgcaaatca tgctggttca gaaatacttt gatgagcgtg gtcaggatga acgcatcagc
    10741 catatcgttg tcatgggaat cggtgagccc tttgataatt acaacaatgt cttgaatttc
    10801 tttcgtacta tcaatgatga taaaggaatg gctatcggtg ctcgtcacat cacggtttca
    10861 atctcaggtt tggctcataa aattcgtgac tttgctgatg aaggggttca ggtcaatctt
    10921 gccgtgtctc ttcacgcacc caacaatgaa cttcgttcaa gtatcatgaa gattaaccgt
    10981 gcctttcc
//
LOCUS       DAVBIC010000063        10604 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.063, whole genome shotgun sequence.
ACCESSION   DAVBIC010000063 DAVBIC010000000
VERSION     DAVBIC010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10604)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10604)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10604
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.063"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            complement(7..1221)
                     /locus_tag="VQ664_001872"
     CDS             complement(7..1221)
                     /locus_tag="VQ664_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET2789979.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            complement(1377..1670)
                     /locus_tag="VQ664_001873"
     CDS             complement(1377..1670)
                     /locus_tag="VQ664_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789980.1"
                     /translation="MMKNSFQKSNFLYYGIILVSVLVKVIMICQLESLVPLLYPSFIG
                     FLVFHVLYHLILFLVAKRSGRWDYLMIWGLFLMFNLLYDSFLGLLFLGLSFGM"
     gene            1832..2284
                     /locus_tag="VQ664_001874"
     CDS             1832..2284
                     /locus_tag="VQ664_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HET2789981.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIAHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            complement(2319..3707)
                     /locus_tag="VQ664_001875"
     CDS             complement(2319..3707)
                     /locus_tag="VQ664_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET2789982.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     AASPSEEDFGQAVSQLHQALDKAAGKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            3773..4735
                     /locus_tag="VQ664_001876"
     CDS             3773..4735
                     /locus_tag="VQ664_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HET2789983.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKDYMEG"
     gene            complement(4732..4923)
                     /locus_tag="VQ664_001877"
     CDS             complement(4732..4923)
                     /locus_tag="VQ664_001877"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789984.1"
                     /translation="MNTIERTRRLVKGCATHCFEVVDETDEVSSKHVFEVVDRTDEVS
                     NHTYGRATLTWFAEIFEEY"
     gene            complement(4987..5997)
                     /gene="ccpA"
                     /locus_tag="VQ664_001878"
     CDS             complement(4987..5997)
                     /gene="ccpA"
                     /locus_tag="VQ664_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HET2789985.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKVGITYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
     gene            complement(6422..7021)
                     /locus_tag="VQ664_001879"
     CDS             complement(6422..7021)
                     /locus_tag="VQ664_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2789986.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLTLQPDVESVLQAKNGQEAIQLLEK
                     ESVDIAILDVEMPVKTGLEVLEWIRSERLETKVVVVTTFKRAGYFERAVKAGVDAYVL
                     KERSIADLMQTLHTVLEGRKEYSPELMEVVMTRPNPLTEQEIAVLKGIARGLSNQEIA
                     DQLYLSNGTIRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(7022..8119)
                     /locus_tag="VQ664_001880"
     CDS             complement(7022..8119)
                     /locus_tag="VQ664_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET2789987.1"
                     /translation="MLERLKSIHYMFWASLIFMIFPILPVVTGWLSAWHLLIDILFVV
                     AYLGVLTTKSQRLSWLFWGIMLIYVAGNTAFVAVNYIWFFFFLSNLLSYHFSVRSLKS
                     LHVWTFLLAQVLVVGRLLIFQRIEVEFLVYLLGILTFVDLMTLGSVRIRLVEDLKEAQ
                     TKQNTQINLLLAENERNRIGQDLHDSLGHTFAMLSVKTDLALQLFQIQAYPQVEKELR
                     EIQQISKESMREVRTIVENLKSRTLTSELETVKKMLEIAGIEVEIANQLDTASLTQEL
                     ESTASMILLELVTNIIKHAKASKAYLKLERTDQELLLMVRDDGKGFETVTENELHTVR
                     ERVLPFSGEVSVISQKHPTEVQVRLPYKERK"
     gene            complement(8119..8856)
                     /locus_tag="VQ664_001881"
     CDS             complement(8119..8856)
                     /locus_tag="VQ664_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2789988.1"
                     /translation="MKRWIALNKIEFLLTKRQSVYYLLSVGMPTAFYLFFSGMYQDTP
                     GGPANFMRDYLISMTAFSMMSTAIFSFPAVLHTDKMNNWQKTLRHSPVNMVEYYLSKI
                     TSMMVDYLVSILVVFSVGHLVRGVDMSLGSWIGAAFLLIVGSIAFVALGLTLTLLPSS
                     QLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQAIGKCLPTYQLMELLKTFLNEGSINL
                     SATVYLLVFSAVLFGLTIYLQGHKENA"
     gene            complement(8858..9742)
                     /locus_tag="VQ664_001882"
     CDS             complement(8858..9742)
                     /locus_tag="VQ664_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2789989.1"
                     /translation="MNMIKVQGLHKNIKSKAILKDISFEVAEGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVYIQDLPVTSSKLDYTRSYLPQENVIVQKLKVKELIAFFQRIY
                     PNPLNNQEIDQLLQFDQQQKEQFAEKLSGGQKRLLSFILTLIGRPKLVFLDEPTAAMD
                     TSTRQRFWEIVRDLKAQGVTILYSSHYIEEVEHTADRILVLNKGELIRDTTPLAMRSE
                     EIEKHFILPLAYKEVVEKSVLVENWVQKQDALQVVTCEADAFWELLVQAGCRIQEIEV
                     NNRSLLDTIFEETQKGDD"
     gene            complement(9729..9923)
                     /locus_tag="VQ664_001883"
     CDS             complement(9729..9923)
                     /locus_tag="VQ664_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789990.1"
                     /translation="MKKAILFLFIGLSLVVWLVEMFTGWFDQSFLHQVIRGAWGLGFM
                     ISVVFPMGMEWLKGEYYEHD"
     gene            complement(9920..10126)
                     /locus_tag="VQ664_001884"
     CDS             complement(9920..10126)
                     /locus_tag="VQ664_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789991.1"
                     /translation="MEEEEMRNKMIIAVSLVVAGVMTYLMFSGLDEGFYHFPWELFAS
                     FGIMSWLIREGLKLVRDVKKELEK"
BASE COUNT         3213 a         2412 c         1931 g         3048 t
ORIGIN      
        1 caagccctat ctacgatact gtttcaagaa acgagtcatc ttttcttgga tttgggctaa
       61 ctcatcaaca cgaggaaggt aaacgatacg gaagtggtct ggttcctgcc agttaaagcc
      121 tcgaccatga accaagagaa ccttttcctg cttcaagaaa tcaaggacaa actgctcatc
      181 atcatcgata cggtacatat tgcggtcgat ttttgggaag atatagagcc ccgccttggg
      241 tttaacggca gacaaacctg gaatatcttg aatggcatta tagatgaaat ttctttgctc
      301 gtagattcgt ccaccaggaa gaagcaattc atcgactgat tggtgacccc ccaaggaagt
      361 ttgtacgact tgttgggcca aaacgttaga gcaaaggcgc atattggaca gcatattgag
      421 cccttcgata tagcccttaa catgagtctt agggccagac aagaccatcc aacccacacg
      481 gaaacctgct atgcggtggg attttgacag accattcatg ctgacacaga agacatctgg
      541 tgccaagctc gccacaggcg tatgcacatg tccgtccatt accatgcggt catagatttc
      601 atccgcaaag ataatcaaat cgttttgacg ggcaatctca ataatctcca gcaagagttc
      661 cttaggataa agggctccag ttgggttatt tggattgata aggacaattg ccttggtatt
      721 ggaagtgatt tttgacttga tatcgtcaat atctgggtac cattccacag cttcatcaca
      781 gatatagtga acggcatttc ctccagctag gctgacagcc gccgtccata gaggatagtc
      841 tggcattggc actaagacct catccccatt gtccaaaagc ccctgcatgg acatgacaat
      901 caactcactg acaccatttc caaggtaaat atcatcaata tctacgtttg ggaatttctt
      961 cagctggcaa tactgcatga tggccttacg ggctgagaaa atccctttgg agtcagaata
     1021 gccttcacta tcacgcgcat tcataatcaa gtcatgaatg acctcgtctg gcgctgtaaa
     1081 gccaaattct gctggatttc ctgtattcag acgtaaaatc ttttctccat tcgctcgcat
     1141 ccgcatggct tcttccaata caggaccacg gatatcataa gcaacatgct ctaacttact
     1201 agacttgtta tattctttca tcttgtttcc tcaattcatc aggatagtaa cattatacca
     1261 ctagaaagag aatgcgacaa gtttactgaa atgtgttact agtttcgtat agaagaaaaa
     1321 ccttgctaaa ggcgaggtta agaacgtaga gatagcaggc attttgcaaa gacacatcac
     1381 ataccaaaag ataaacctag aaaaagcaag cctagaaagg agtcataaag aagattaaac
     1441 atgaggaaaa gcccccatat catcaagtaa tcccaacgcc cacttcgttt tgcaactaga
     1501 aataagatta gatggtagag tacatgaaag actaaaaatc caataaaact tggataaaga
     1561 agcggtacca gactctctaa ttgacagatc atgatcactt ttaccaagac tgaaactagg
     1621 ataattccat aatacaggaa atttgatttt tgaaaagagt ttttcatcat tctcccttcc
     1681 ttcacttctt tccttctatc ctttctttta ttttatcata tatttatata gattttaagc
     1741 cctaatattc ttttgaaaaa tacttttttt gctttacttc tatagtgaaa aggtttacaa
     1801 ttatagtaag aaaatttcag gaggtttcat tatggcacaa cgttaccaaa atatcatggt
     1861 cgcaatcgat ggttctaagg aagcggactt ggcttttgtc aagggagttc attctgctct
     1921 acgaaacgac gctaaactca ccatcgcaca tgtcattgac acacgcgctc tccaaagcgt
     1981 atccaccttt gatgctgaag tttacgaaga actccaagtc gacgctgaaa gtctgatgaa
     2041 agagtacgaa aaacgtgcta aagatgctgg ggtagcagat gttcatatcg tcattgaaat
     2101 gggaaatcca aagaccctgc tagcacgtac tattccagat gccgaggaag tggacctcat
     2161 cctcgttggc gcaactggtc tcaacgcctt tgaacgcctc ttggtcggct cttcatctga
     2221 atacatactc cgccatgcta aggtcgattt gctggttgtg agagaacaag aaaaaacctt
     2281 ataatcacaa agaaaaggag cccctagctc ctttttgttt acgatttatt tctctcttta
     2341 tggcgttcgt aagccttgag ctggcgctgc agttcctttt taatagcagg ttctggagca
     2401 tatttttctt cccaattatc tggttttaag attttatggg tcactggatc aaaatgagcc
     2461 ttgccatctg gaaaaatttt ccccatattg gcctgatgga caatatcaaa aatacgttct
     2521 gggtccaccc ccatcaagac aaaactgccg taggtgaagt aaagcgtgtc aatcaaggca
     2581 tccacttgcc ctatcaaatc ttgctgagca ggtgtcttct tggctacttt acctgctgcc
     2641 ttatcaaggg cctgatgaag ttgcgataca gcttgaccaa aatcttcttc agaaggactg
     2701 gctgctcgaa caaactccac caattcttct attttaaaac cagccctatg ggttgcaccc
     2761 tctaaatccc aagctcgagg ttcttcttgg gttcgttcat ccatcatgtg gtggaaggtc
     2821 ttgaccttat tgaaatgata gtcacggctg acaaagactt tttctgaaga caaaacacca
     2881 aaatgttcca aggccttgtg gatcccatct tgttgattgc tagtggtaat gtgcttggca
     2941 gcttccttga cactgctact accatttccc atagcgaccg acataccgac gccagccagc
     3001 atttcaaggt cattatctga gtcaccaaaa gccatgactt ggttgaggtc aaagccatat
     3061 tctttcccaa ctcggcgaat gccttctaat ttagaatttc cctgattgat gacatccgat
     3121 gcaaaaggat tgctacgtgt caatttcaag tcttcaaaat cagctgccgc cttctcagat
     3181 tcttctggtg tcatcagcat caaaacttgg tagataggct gattcatcag gtgaagcagg
     3241 tcctcttcct tttggggaac aaccttgctg accatgcgat taaaagactg actcaccgtc
     3301 cgagttaaaa cagagggaac gaagcgacta attcgttggg aaaaagaacc cagaccaaag
     3361 gacatgattt tagaacccaa catggcatcc ttggtcccta gggcaatctc cgtgccctct
     3421 tttttagcat agctaattag atggcgcaaa tgtaacttgg aaatagggct cgtgaacaag
     3481 actctgtctt tactaaagat atactggcca ttataggtta ccgcaaaatc cagatccaaa
     3541 tcgtccatca attccttaac aaaaaaaggt cctcgccctg tcgctacgcc aactagtacc
     3601 ccttgttctt tgacaatctt aatcgcgtcc ttagtggatt tcaaaacact cttgcgattg
     3661 ttgaccaagg ttccatcgat atcaaaaaaa acagctttga cttccatcct attccaatct
     3721 ccccttttgt gatacaatga ttataccaca tttcagaaag agtgagtaaa tcatgcctaa
     3781 gaaaatcctt gttttacata cgggtggaac tatttccatg caggccgatg cttctggcgc
     3841 tgttgtgacg agttcagata atcccatgaa ccatgtgtcc aacccacttg aaggaatcca
     3901 agtccacgcc ttggactttt ttaaccttcc aagtccccat atcaaaccca aacatatgct
     3961 ggtcctctac cagaaaatta aagaggaagc agataactac gatggagtgg taatcacaca
     4021 cggaaccgat actttagagg aaacagccta tttccttgat accatggaag ttccccatat
     4081 gcctatcgtt ctaacaggag ccatgcgtag ctccaatgag ctcggtagtg atggtgttta
     4141 taattaccta agtgctttac gagtggccag cgatgacagg gctgctgaca aaggagtttt
     4201 ggtcgttatg aacgatgaaa tccacgctgc caagtatgtc accaaaacac atacgactaa
     4261 tgtcagcacc ttccagactc caacacatgg ccccctcggt ctcatcatga aacaggaaat
     4321 cctctacttc aaaacagctg aacctcgtgt tcgctttgac cttgatcaca tacaaggttt
     4381 agtccctatc atctcggctt atgctggtat gacagatgag ctgattgata tgctggattt
     4441 agaacacttg gacggtttga ttatccaagc cttcggagct ggtaatattc ccaaagaaac
     4501 ggctcaaaaa ttagaaagcc ttctgcaaaa aggaatccca gtcgctctgg tatcacgatg
     4561 ctttaacggt attgccgagc ctgtttatgc ctaccagggt gggggcgtac agttgcaaaa
     4621 agcaggcgtt ttctttgtta aagaactcaa cgcccaaaaa gctcgcttga aactcctcat
     4681 cgccctcaat gccggactaa caggacaggc tttgaaagac tatatggaag gctaatactc
     4741 ttcgaaaatc tctgcaaacc acgtcagagt cgccctaccg tatgtatggt tactgacttc
     4801 gtcagttcta tctacaacct caaaaacatg ttttgagctg acttcgtcag tttcatctac
     4861 aacctcaaaa cagtgtgttg cgcagccttt aaccagccgc ctagtccgct ctatggtatt
     4921 cattaagtca acatctcttg tttaagagca caaaatcagg aaatcttctc gattccctga
     4981 ttttttctat ttacgttttc gtgttgagct acgttctgtc aaaccatgag gtaagagaac
     5041 ttcacgttct tccaactctt ccttatgcat aatcttggtc aacatacgca tactaatggc
     5101 accaaggtca taaagaggtt gggcaatcgt tgtcaagttt ggacgggtaa agcgtgagat
     5161 ttgtgaatca tcactagtaa taatttcaaa atcttctggc acagaaacac ccttatcagc
     5221 caaaccgttc aagactcctg ctgccaactc atcacctgtc acaactgctg cagttgcatt
     5281 tgatgaaatc aaacgctctg ctaaggcgta accatcatca tagctatatt tagattcaaa
     5341 taccaaaccc tcactataag tgattcctac ttttttcaag gtttccttgt agccaactaa
     5401 acgaacctta ccattgatgt catccactag cggaccgcta acgaaagcaa tacgctcatt
     5461 ttctttagca aggtagctca ctgcatcaat tgttgcttgc ttatagtcaa tattgacact
     5521 tggcaactgg tgctcaacat cgacagttcc tgcgagaaca atcggagtac gtgaacgcga
     5581 aaattctgag cgaattttat ctgtcaagtg ataacccata tagataatgc catctacctg
     5641 ctttgaaaag agggtattga caacagaaac ttctttctcg ttatcttcat cgctattagc
     5701 taggacaata ttgtacttgt acatttctgc aatatcatca atccccttag ccaaactcga
     5761 aaaataacca ttggtaatat ttggaatcac gacaccgaca gtggttgtct ttttacttgc
     5821 aagaccacgc gcaactgcat ttggacgata atccaaacga tcaattacct ctagcacttt
     5881 tttacgggta ttctctttta catttttatt gccattgacc acacggctga ccgtcgccat
     5941 ggaaacacct gcttcacgag cgacatcata aatggttact gtatcatctg cattcattcc
     6001 ttttcctgtc ctttctatct cacacattct tttacaagta gaggtactga ttgaagctct
     6061 atatctactt acaaaagtga agatgtgaaa atttcgtttt catatttcta cttattccat
     6121 tctatcacta attgtaaaca ctttcaagtg ttttttgaag attgattgaa aaaatttcat
     6181 agaaaaccta ggtttagctc cttgctacca ccttagacta aataaaaagg aggaaactaa
     6241 gcccttctaa agttatagta aaatgaaata agaacaggat aaatcgatca ggacagtcaa
     6301 atcgatttct aacaatgttt tagaagtaga ggtgtactat tctagtttca atctactata
     6361 ggtattgttc cattcactac cgtcaatttt agcacatagt cttcatgaaa atattatatc
     6421 atcataacca accagattct tttgcgatat tagctgcctc tgttcgatta ccagcatcca
     6481 gttttgaaag aatattggtg acatagtttc gaatagttcc gtttgagagg taaagctgat
     6541 ctgcgatttc ttggttggat aagccccggg cgattccctt taagacagca atctcttgtt
     6601 ctgtcaacgg attgggacgg gtcatcacca cttccatcaa ttcaggcgaa tactccttgc
     6661 gtccttcgag gacggtgtgc aaggtttgca tgaggtctgc aatgcttcgt tcctttaata
     6721 cataagcatc cactccagcc ttgaccgcac gttcaaaata cccagcacgc ttgaaggtcg
     6781 tcaccacaac cacctttgtt tcaagccttt ctgatcgtat ccactccaag acttcaagac
     6841 ctgtcttaac aggcatttct acgtcaagga tggcgatatc tacagactcc ttttctaata
     6901 gttggattgc ttcttgccca ttcttggctt gaaggacaga ctccacatct ggttgaagcg
     6961 tgagcaattg acacatagca tctcgcaaca tactttgatc ttctgcgact aatactttca
     7021 tctactttct ctccttataa ggtagtcgaa cttgcacttc cgttggatgt ttctgactga
     7081 ttacacttac ttctcctgaa aatggaagga cacgttctcg aactgtatgg agctcatttt
     7141 ctgttacagt ttcaaaacct ttcccgtcat ctctgaccat caggagcaat tcctgatctg
     7201 tgcgttctaa ttttaagtag gctttagacg ctttagcatg tttgatgatg ttggtcacta
     7261 attcaagcaa aatcatggaa gccgttgact ctaattcctg agttaagcta gctgtatcta
     7321 gttgattagc tatttccacc tcaattccag caatttctaa catctttttc acagtctcta
     7381 gttcggatgt caaagttcta gacttaagat tttccacaat ggttcgcact tcacgcattg
     7441 attctttgct aatctgctgt atttctctta attccttttc cacttgtgga taagcctgta
     7501 tttgaaataa ctgcaaggct agatcagttt taacactaag catagcaaag gtatgcccca
     7561 gactatcatg caaatcttga ccgatacgat tgcgctcatt ttctgctagc aatagattta
     7621 tctgggtatt ttgcttagtc tgagcttctt tcaaatcctc gacaaggcga attcgaaccg
     7681 agcccaaagt catcaaatca acaaaagtaa gaattccaag cagatagact agaaactcaa
     7741 cttcgattct ctgaaaaatc aaaagtcgcc ccacaacaag gacttgagca agaagaaaag
     7801 tccagacatg taaagacttt aaactacgta cgctgaaatg ataacttaag agattggaaa
     7861 ggaaaaagaa aaaccagata taattcacag caacaaaggc ggtattccca gctacataga
     7921 tcagcatgat cccccagaaa agccaagata ggcgctggct cttagttgtt aaaacaccca
     7981 aatatgccac tacaaataga atatcaatca ataaatgcca ggcagaaagc cacccagtca
     8041 ctacaggtag gatggggaaa atcataaaaa ttaaactggc ccaaaacata tagtgtatgc
     8101 ttttcagtct ttcaagcatt aagcattctc cttatgacct tgaaggtaaa tggtcaaacc
     8161 aaacaaaact gctgaaaaaa caagtagata aactgtggct gatagattga tgctaccctc
     8221 gtttaagaag gtcttgagca actccatcaa ctgataagtt ggtaggcact tcccgattgc
     8281 ttgcatccag tctggaaata aagagatggg catccagagt ccacctaaaa cagccaagcc
     8341 tagatagaga agattgccca cgacagacat cagctgacta gaaggcaaga gtgtcaaggt
     8401 caagccaagc gctacaaaag ctatacttcc tactatcagc aagaacgcag ccccaatcca
     8461 gcttcctaaa gacatatcca cacctctgac caagtgccca actgagaaaa caaccaggat
     8521 tgagaccaaa taatcaacca tcatacttgt tatctttgat agataatatt ctaccatatt
     8581 tacagggcta tgacgcaatg ttttctgcca gttgttcatc ttatcggtat gtaagacagc
     8641 tgggaatgaa aagatagcgg tcgacatcat ggaaaaggca gtcatggaga tgaggtagtc
     8701 gcgcataaaa ttagccggtc cacctggtgt gtcctggtac atgcctgaaa agaatagata
     8761 gaaggctgtc ggcatcccta cagataataa ataatagact gattgccgtt tggtcaatag
     8821 aaattctatc ttgtttagtg caatccatcg tttcatctta gtcatctccc ttctgtgttt
     8881 cttcaaagat tgtatccaac aaactacgat tattgacttc gatttcttgt atcctacatc
     8941 ctgcttgaac taacagttcc cagaaagcat ccgcttcgca tgtgactact tgtaaggcat
     9001 cttgtttttg tacccagttt tcaaccaaga ctgacttctc aacgacttcc ttgtaagcta
     9061 gcggaaggat aaaatgcttt tcaatctcct cactacgcat agctagaggc gtcgtgtcac
     9121 gaatcaactc tcccttattt aaaaccaaaa tccggtcagc tgtatgctct acctcttcaa
     9181 tataatgaga cgaatagaga atggtgactc cttgcgcttt taggtcccga acaatttccc
     9241 aaaaacgttg acgagttgaa gtatccatgg cagcagttgg ctcatctaaa aagacaagct
     9301 ttggtcgccc aattaaggtc aagataaaag ataaaagacg cttttgccca cctgacaatt
     9361 tttctgcgaa ttgctctttc tgttgctggt caaactgtaa tagttgatcg atttcctggt
     9421 tgttcaaggg atttggatag atacgttgaa agaaagcaat caactcttta acctttagtt
     9481 tttgaacaat tacattttct tgagggagat aggatctcgt atagtctaac ttagagctcg
     9541 ttaccggcaa atcttggata tatacttgcc cactggtgac caatttatct ccaagcaaac
     9601 agtccaagag tgtcgtctta ccagctccat ttggcccaat caaggcgacg cattcacctt
     9661 cagctacctc aaaggaaata tccttcaaaa tagccttact tttgatgttt ttatgtaagc
     9721 cttgtacctt aatcatgttc ataatattct cctttcaacc actccattcc catagggaaa
     9781 acgacggaaa tcataaatcc taatccccag gcgccgcgaa taacttggtg aagaaaggat
     9841 tgatcaaacc aacctgtaaa catttctacc aaccatacca ctagtgatag tccaataaaa
     9901 agaaagagaa tcgctttttt catttttcaa gctccttttt cacatctctt actaatttca
     9961 agccttctcg tatcaaccaa gacatgattc caaagcttgc aaacaactcc caaggaaaat
    10021 gatagaatcc ttcgtccaat cctgagaaca tgagataagt catgactcct gctactacta
    10081 aactcactgc gataatcatt ttatttctca tctcttcttc ctccatttca tactacaatt
    10141 atagtctttt gaaatcagag gagatagaag cttctgtcac taaaaaatat gacaaatgtc
    10201 ataaaaaatt ctgttcaaaa caagcaagat acactataca ataaaacaca attagataaa
    10261 tctaaggcaa cttcctcaaa agagatatca aaccccattc acactataat gtaaactaat
    10321 acttatttaa agtcaaaaga gcggaaattt ttatcgtaca aacatatata ttataggtaa
    10381 gacaaaaaac tcttcaatta ctttcttaaa aatttatagg agttataaaa tctattaaat
    10441 ttcaatgtgg atacctaaac tacagtattt attgaaaaga ctggagacaa aaagtatacg
    10501 ctgccaaaat gaattgctga aaatcaaaaa agagagaagc aaactgattc tctcttaatg
    10561 tatataatat ctagttataa aaatacacac tcacatatct ctgt
//
LOCUS       DAVBIC010000064        10363 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.064, whole genome shotgun sequence.
ACCESSION   DAVBIC010000064 DAVBIC010000000
VERSION     DAVBIC010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10363)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10363)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10363
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.064"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            <1..171
                     /locus_tag="VQ664_001885"
     CDS             <1..171
                     /locus_tag="VQ664_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein"
                     /protein_id="HET2789992.1"
                     /translation="VKDGDTWYYLEASGAMKASQWFKVSDKWYYVNGSGALAVNTTVD
                     SYRVNANGEWVN"
     gene            complement(401..1381)
                     /gene="dusB"
                     /locus_tag="VQ664_001886"
     CDS             complement(401..1381)
                     /gene="dusB"
                     /locus_tag="VQ664_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HET2789993.1"
                     /translation="MTNLNTPFMIGNIEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLIN
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKA"
     gene            complement(1368..2240)
                     /gene="hslO"
                     /locus_tag="VQ664_001887"
     CDS             complement(1368..2240)
                     /gene="hslO"
                     /locus_tag="VQ664_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HET2789994.1"
                     /translation="MDKIIKTISESGAFRAFVLDSTETVRTAQERHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGAGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKVAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGAEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            2405..3832
                     /locus_tag="VQ664_001888"
     CDS             2405..3832
                     /locus_tag="VQ664_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET2789995.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELTIHSEDENLRLSIGAATKGRDIRSLFLDSAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSAGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPAFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QTPVYYLKNDLDMEDLAGIRQLLFT"
     gene            3991..5499
                     /gene="glpK"
                     /locus_tag="VQ664_001889"
     CDS             3991..5499
                     /gene="glpK"
                     /locus_tag="VQ664_001889"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HET2789996.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQVDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEVDD"
     gene            5541..7367
                     /gene="glpO"
                     /locus_tag="VQ664_001890"
     CDS             5541..7367
                     /gene="glpO"
                     /locus_tag="VQ664_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HET2789997.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGVGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPTANKVLSKDQVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKHLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELALSPVDFLLRRTNHMLFMRDSLD
                     SIVEPILDEMGRFYDWTEEEKATYRADVEAALANNDLAELKN"
     gene            7437..8141
                     /locus_tag="VQ664_001891"
     CDS             7437..8141
                     /locus_tag="VQ664_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HET2789998.1"
                     /translation="MMNELFGEFLGTLILILLGNGVVAGVVLPKTKSNSSGWIVITMG
                     WGIAVAVAVFVSGKLSPAHLNPAVTIGVALKGGLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEAEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            8438..8641
                     /locus_tag="VQ664_001892"
     CDS             8438..8641
                     /locus_tag="VQ664_001892"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2789999.1"
                     /translation="MPKWSNPDYVNELDPKIVDMLVEFHKSQGTLETPEAQAEIAQKR
                     EEIEQRRAELEDKKQELLNRLNK"
     gene            complement(8728..9315)
                     /locus_tag="VQ664_001893"
     CDS             complement(8728..9315)
                     /locus_tag="VQ664_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2790000.1"
                     /translation="MFVFADDSLSANSKVVSGEAQFENGSSVRFGDTQVNILSDEVLE
                     VVNPDGSVDTIERRADGVYINGAFYMAYQKNEIDLNISFRSYDPNVWNYVNTIHGNKQ
                     ANTFANFMTGAGISYMIGRIGTLLGGPWGAIIGGAYFGIQAYQSYLDSQSPYPYYITS
                     TYIHVAQKKWKFITEYYRNSNYTGYVKTVTTYVNF"
BASE COUNT         3016 a         2047 c         2369 g         2931 t
ORIGIN      
        1 gtgaaagatg gagatacctg gtactatctt gaagcatcag gtgctatgaa agcaagccaa
       61 tggttcaaag tatcagataa atggtactat gtcaatggct caggtgccct tgcagtcaac
      121 acaactgtag atagctatag agtcaatgcc aatggtgaat gggtaaacta aacctaatat
      181 aactagttaa tactgacttc ctgtaagaac tctttaaagt attccctaca aataccatat
      241 cctttcagta gataatatac ccttgtagga agtttagata aaaaaataac tctgtaatct
      301 ctagccggat ttatagcgct agagactacg gagttttttt gatgaggaaa gaatggcggc
      361 attcaagagg ctctttaaga gagttacggg ttttaaacta ttaagccttc tccaattgca
      421 agagggcttc aatctctgcc agggtgctag cttgcgaaat ggctccacgg agtttggcag
      481 cgccagatgt tccacggaga tagtgaggag cgaggccgcg gaattcacga actgcgacgt
      541 tttctccttt gaggttaatc aatcgtttca agtgttcgta ggcgatcttc atcttgtctt
      601 caaaggtcaa atcaggtagg atttctcctg tttcaaagta atggttgatt tggttgaaga
      661 ggtaaggatt tcccatggca gctcggccaa tcatgactgc gtcagcacca acttcttcga
      721 tgcgttgctt ggcttcttgg acagtacgga tatcaccgtt ggcgatgaat ggaatcttgg
      781 ttagagcttg ggcaaccttg taaagggtct caaggtctgc gtggccagta tacatttgtt
      841 cacgggtacg gccatgcatg gcgagggcag aaacacctgc agcctcagca gcgagggcat
      901 tttctactgc aagagatggg tccgcccatc cggtacgcat tttgacagta agtgggatat
      961 caaggacaga ctggaccttg ttgatgatag agtagatctt gtcaggatcc ttgagccaca
     1021 tagctccagc ttcgttcttc acgattttgt tgacagggca gcccatgttg atatcgacga
     1081 tatcggtctt ggtgttttct tggatgaatt ctgctgcgcg tgctaggctg tcttcatcgc
     1141 taccaaaaag ttggatagag acagggtttt cgccctcatc gatatgaagc atgtgcaggg
     1201 ttttttcgtt gttgtattgg attcccttgt cagagaccat ttccattaca acgagtccag
     1261 ctccgagctc ttttgcgatg gtacgaaagg ctgagttggt cacgccagcc ataggcgcta
     1321 aaacggtacg attgggaatc tcaatattgc caatcataaa aggtgtatta agatttgtca
     1381 cgaatgagtt cctccaggtc cttttcatca aagttgtaag tagtttggca gaattgacaa
     1441 gtgatttctg ccccgtggtc ttcctctttc atttcctgta agtctgagct tggaaggctg
     1501 gcaagagcgt tcataaagcg ttcatggcta cagtcacatt ggaaacggat ttcttcttca
     1561 gaaagacgct tgtaggcttc gtccccgtag atagccttga ggagggcttc gatatggtcg
     1621 tcgctttcga gaagagtaga gatagctggc atttcttgga tgcgtttttc aaagcgagca
     1681 atctcttctt tcttggctcc tggcaagact tgaactagga aaccacctgc aaccttgacc
     1741 ttgtcttcct cgtccaaaag gacattgagg ccgaccgctg aaggcgtttg ttggctttca
     1801 gtaaggtaaa aggcaaggtc ttcaccgatt tctccagaga tgaggggagt tatagagttg
     1861 taaggatttc cagcaccgta gtctgtgata acgaggaatt gaccatttcc aacaaaaggt
     1921 ccgactagga cttcaccagt cgcagtcttt ttgatgtcaa caccaggatt ttgaacatag
     1981 cctttgacgt tccccttggt atcagcgacg gtgataatag cacctagaga gctagagccc
     2041 aacaccttaa ctgtaagttt ggtatttcct ttttcattgg ctgcgagaat ctggctagcg
     2101 ataagagttc gaccaagcgc tacagttgag ctagcttggg tttgatgtct ttcttgagca
     2161 gtgcggacgg tttccgtgct atcaaggaca aaagcacgaa aggctccgct ttctgatata
     2221 gttttaataa ttttatccat agctactatt ttagcataaa aatgcccaaa gggggagccg
     2281 tgtgtttact gattttcagg ataatggacc aggaaatcag catgaaaata aaaagagaaa
     2341 cagattattt cagcatttgt aagatttatg ctatgcttaa ggtagaaaat gaaaggggta
     2401 acaaatgtat ttaggagatt tgatggagaa agccgagtgt ggtcaatttt caatcctttc
     2461 ctttctatta caagagtctc agacgaccgt caaggctgta atggaagaaa caggattttc
     2521 aaaagcaacc ctaaccaaat atgtcaccct gctcaatgac aaggctttgg atagtggctt
     2581 agaactgact attcactcag aagatgaaaa tctgcgtctg tctatcggtg cagctaccaa
     2641 ggggagagat attcggagct tgtttttgga tagtgctgtt aaataccaga ttttggttta
     2701 tcttctctac caccaacagt ttttagccca tcagctggct caagaattgg tgattagcga
     2761 ggctacgctt ggtcgtcact tggctggttt aaatcagatt ttgtcagaat ttgatttatc
     2821 catccaaaat ggacgctgga gaggtccaga gcatcagatt cgctatttct atttctgtct
     2881 tttccgaaag gtctggtcga gtcaggaatg ggaaggtcac atgcagaaac cagagagaaa
     2941 acaggagatt gccaatttag aggaaatctg cggtgcaagt ttgtctgcgg ggcagaaatt
     3001 ggacttggtt ctctgggctc acatcagtca acaacgtctt cgggtcaatg cttgtcagtt
     3061 tcaagtcata gaagagaaaa tgcgagggta ttttgacaat atcttttatc ttcgtttgct
     3121 gagaaaggtt ccgtcctttt ttgctgggca acatattcca ctaggagttg aggatggtga
     3181 gatgatgata ttcttctctt ttctcctatc tcatcgcatt cttcctcttc atactatgga
     3241 gtatattctt ggttttggag ggcagttggc agatttactg acgcaattga ttcaagaaat
     3301 gaagaaggag gaactattgg gggattatac agaggaccat gtcacctatg aactcagtca
     3361 gctttgtgct caagtctatc tctataaggg ctatatttta caggatcgct acaagtacca
     3421 gttagagaat cgtcatccat atttactgat ggaacatgat tttaaagaga cagcagagga
     3481 gatttttcat gctctacctg cttttcaaca ggggacagat ttagataaga agattctctg
     3541 ggaatggctc cagttaatcg aatatatggc tgaaaacggt ggccagcata tgcggattgg
     3601 tctggatttg acatctggtt ttcttgtctt ttcaaggatg gcagccattt tgaaacggta
     3661 tttggaatac aatcgtttta ttaccattga agcttatgac cctagtcggc attatgattt
     3721 gctggttacc aataacccga ttcataagaa ggaacagaca ccagtctatt atttaaaaaa
     3781 cgacttggat atggaagatt tggcagggat tcgtcagtta ttattcactt aaaaggcttg
     3841 gttaatctag gtcttttttg tgaaattcac acaatctcct cacatttttt taaaaattaa
     3901 aaaaagttga taaacaagaa agcgctttat tttgtatact agtaagtgta aagaggaaac
     3961 acctcaagat ctttatcagg aggacagtac atgtcacaag aaaaatacat catggccatt
     4021 gaccagggaa ctacaagttc tcgtgccatc attttcaaca aaaaagggga aaaggttagc
     4081 tcgagtcaaa aagagtttac ccagattttc cctcaggcag gttgggttga gcacaatgcc
     4141 aatgaaattt ggaactctgt tcagtcagtt attgcgggtg ctttcatcga aagtggtgtc
     4201 aagccaaatc aaatcgaggc aatcgggatt accaaccaac gtgaaacaac ggttgtctgg
     4261 gataagaaaa caggacttcc tatctacaat gctatcgttt ggcagtcacg ccagacagca
     4321 cctttggctg agcaactaaa aagccaaggt tatgtggaaa aattccatga aaagactggt
     4381 ttgattattg atgcttactt ctctgctacc aaggttcgtt ggattttgga tcatgtagaa
     4441 ggtgctcaag agcgagcaga aaaaggggaa ttgctctttg gtactatcga tacttggttg
     4501 gtttggaaat tgactgacgg tgcggctcac gtgactgact actcaaatgc agctcgtacc
     4561 atgctttata acattaaaga actcaaatgg gatgatgaga ttttggaaat ccttaacatt
     4621 ccgaaggcta tacttccaga agttcgttct aactccgaaa tctacggcaa gacagctcca
     4681 ttccatttct acggtggaga ggtgccaatc tcaggtatgg ctggggacca acaagcagcc
     4741 ctctttggac agttggcttt tgagccaggt atggttaaga atacttatgg aacaggctct
     4801 ttcatcatca tgaatactgg ggaagagatg cagttgtctg aaaacaacct cttgacaacc
     4861 attggttacg gaatcaacgg taaggtttat tatgccttgg aaggttctat cttcatcgca
     4921 ggaagtgcta ttcagtggct tcgtgacggt cttcgcatgg ttgaaaattc accagaatct
     4981 gaaaaatacg ctcgtgattc tcacaacaac gatgaagttt atgtcgttcc agcctttaca
     5041 ggtctaggcg ctccatactg gaaccaaaat gctcgtggtt ccgtctttgg tttgactcgt
     5101 ggaacaagca aagaagactt tatcaaggcg actttgcaat ctattgctta tcaagtgcgt
     5161 gatatcatcg acaccatgca agtggatact cagaccgcca ttcaagtact gaaggtggat
     5221 ggtggtgcag ccatgaacaa cttcctcatg cagttccagg cggatatttt aggcattgac
     5281 attgcacgtg ctaaaaacct ggaaacaaca gctctaggag cggccttcct agcaggtttg
     5341 tcagtagggt actggaaaga cttggacgag ttgaaactct tgaacgagac aggagaactc
     5401 tttgagccat ctatgaacga atctcgcaag gaacaactct acaagggctg gaagaaggct
     5461 gtgaaagcaa ctcaagtctt tgcggaagta gacgactaat actggcagaa taaagcgatt
     5521 tatttagaaa gtgtgtaaat atggaatttt caaagaaaac acgtgaattg tcaattaaaa
     5581 aaatgcagga acgcaccctg gacctcttga ttatcggtgg aggaatcaca ggagttggtg
     5641 tagccttgca ggcggcagct agcggtcttg agactggttt gattgaaatg caagactttg
     5701 cagaaggaac atctagtcgt tcaacaaaat tggttcacgg aggacttcgt taccttaaac
     5761 aattcgacgt agaagtggtc tcagatacgg tttctgaacg tgcagtggtt caacaaatcg
     5821 ctccacacat tccaaaacca gacccaatgc tcttaccagt ttacgatgaa gatggagcaa
     5881 cctttagcct cttccgtctt aaagtagcca tggacttgta cgacctcttg gcaggtgtta
     5941 gcaacacacc aactgcgaac aaggttttga gcaaggatca agtcttggaa cgccagccaa
     6001 acttgaagaa ggaaggcttg gtaggaggtg gagtgtatct tgacttccgt aacaacgatg
     6061 cgcgtctcgt gattgaaaac atcaaacgtg ccaaccaaga cggtgccctc attgccaacc
     6121 acgtgaaggc agaaggcttc ctctttgacg aaagtggcaa gattacaggt gttgtagctc
     6181 gtgatctctt gacagaccaa gtatttgaaa tcaaggcccg tctggttatt aatacaacag
     6241 gtccttggag tgataaagta cgtaatttgt ctaataaggg aacgcaattc tcacaaatgc
     6301 gcccaactaa gggagttcac ttggtagtgg attcaagcaa aatcaaggtt tcacagccag
     6361 tttactttga cacaggtttg ggtgacggtc gtatggtctt tgttctccca cgtgaaaaca
     6421 agacttactt tggtacaact gatacagact acacaggtga tttggagcat ccaaaagtaa
     6481 ctcaagaaga tgtagattat ctacttggca ttgtcaacaa ccgctttcca gaatccaaca
     6541 tcaccattga tgatatcgaa agcagctggg caggtcttcg tccattgatt gcagggaaca
     6601 gtgcctctga ctataatggt ggaaataacg gtaccatcag tgatgaaagc tttgacaact
     6661 tgattgcgac tgttgaatct tatctctcca aagaaaaaac acgtgaagat gttgagtctg
     6721 ctgtcagcaa gcttgaaagt agcacatctg agaaacattt ggatccatct gcagtttctc
     6781 gtgggtctag cttggaccgt gatgacaatg gtcttttgac tcttgctggc ggtaaaatca
     6841 cagactaccg taagatggct gaaggagcta tggagcgcgt ggttgacatc ctcaaagcag
     6901 aatttgaccg tagctttaaa ttgatcaatt ctaaaactta ccctgtttca ggtggagaat
     6961 tgaacccagc aaatgtggat tcagaaatcg aagcctttgc gcaacttgga gtatcacgtg
     7021 gtttggatag caaggaagct cactatctgg caaatcttta cggttcaaat gcaccgaaag
     7081 tctttgcact tgctcacagc ttggaacaag cgccaggact cagcttggca gatactttgt
     7141 cccttcacta tgcaatgcgc aacgagttgg ctcttagccc agttgacttc cttcttcgtc
     7201 gtaccaacca tatgctcttt atgcgtgata gcttggatag catcgttgag ccaattttgg
     7261 atgaaatggg acgattctat gactggacag aagaagaaaa agcaacttac cgtgctgatg
     7321 tcgaagcagc tctcgctaac aacgatttag cagaattaaa aaattaagaa aaaataaaag
     7381 aggtggaggg cagcattcct tgtcgcccgt cccttctttt taatggagac agaaagatga
     7441 tgaatgaatt atttggagaa tttctaggga ctttaatcct gattcttcta ggaaatggtg
     7501 ttgttgcagg tgtggttctt cctaaaacca agagcaatag ctcaggttgg attgtgatta
     7561 ctatgggttg ggggattgca gttgcggttg cagtctttgt atctggcaag ctcagtccag
     7621 ctcatttaaa cccagctgtg accatcggtg tggccttaaa aggtggtttg ccttgggctt
     7681 ccgttttgcc ttatatctta gcccagttcg caggggccat gctgggtcag attttggttt
     7741 ggttgcaatt caaacctcac tatgaggcag aagaaaatgc aggcaatatc ctggcaacct
     7801 tcagtactgg accagccatc aaggatactg tatcaaactt gattagcgaa atccttggaa
     7861 cctttgtttt ggtgttgaca atctttgctt tgggtcttta cgattttcag gcaggtatcg
     7921 gaacctttgc agtgggaact ttgattgtcg gtatcggtct atcactaggt gggacaacag
     7981 gttatgcctt gaacccagct cgtgaccttg gacctcgtat catgcacagc atcttgccaa
     8041 ttccaaacaa gggagacgga gactggtctt acgcttggat tcctgttgta ggccctgtta
     8101 tcggagcagc cttggcagtg cttgtattct cacttttcta gtttatactc ttcgaaaatc
     8161 aaattcaaac cacgtcagcg tcgccttacc gtactcaagt acagcttacg gctagcttcc
     8221 tagtttgctc tttgattttc attgagtatt agaaaacaat tatgttgata gagcttgggc
     8281 aagagcccaa tttcagcaaa aaatgaagta aatcttctca taataaaacg catcatatca
     8341 agcacgaaaa ttccacgagg tcaactacag tcagaaagct gaacaacaag ccaaaacgcc
     8401 caaaaaaggc ggcaaaaagc aagcacctgc aagcaacgtg ccgaaatggt caaatcctga
     8461 ttatgtcaac gaattagacc caaaaatcgt tgatatgcta gtagaatttc acaagtcaca
     8521 aggcactttg gaaactcccg aggcgcaagc agaaatcgcc caaaaacgtg aagaaatcga
     8581 gcaaaggaga gctgagcttg aggataaaaa acaagagctt ttgaaccgct tgaacaaata
     8641 gagtttcgca agtattatgc ttacaaatta cttgagcaat taactaaaat ataaaccctg
     8701 cctttatatc taggcagggt ttatatttta gaaattcacg taggttgtta cggtttttac
     8761 atacccagta tagtttgagt ttctatagta ttcagtgata aacttccatt ttttttgagc
     8821 aacatggata taagtacttg ttatgtagta tggatatggg ctttgtgaat ccaagtaaga
     8881 ctgataagct tgtataccaa aatatgctcc accaattatt gcaccccatg gaccccccaa
     8941 taaagtacct atcctaccaa tcatataact gattccagca ccagtcatga agttagcgaa
     9001 tgtgttagct tgtttattcc catgtattgt gttgacgtaa ttccaaacat taggatcgta
     9061 tgatctaaaa gatatattta ggtcgatttc attcttttga taagccatat aaaatgcccc
     9121 attgatatag acgccgtcag cacgtcgttc aatagtgtct acacttccat ctggattgac
     9181 aacctcaaga acttcatcgc ttaaaatatt tacttgcgta tctccgaacc gcactgatga
     9241 gccattctca aactgagcct caccagatac aactttagag tttgccgata agctatcatc
     9301 agcaaaaaca aacaagcgac ggggaaatgc tagacataca gaaaacagac ataactagca
     9361 aacacatgca tttaaacatc ttagacataa cggaaactcc tttgtatttt tgattttttt
     9421 caacttttat tatacaataa aaccaaataa aaagaaagcg gtaacaatat gcttaatgcg
     9481 aaaatttttt atatattttt atgtttgatc gttatcgaaa ctacaggctt gttgttgttg
     9541 aaaagaggtc tcgaaatggg ttatttagac acagaagcta ttatcctcgc agttttttca
     9601 tttgcttttt acaacctatg ttcattcgct tgggtctgct ctacaataaa aaacaataaa
     9661 aaataaatag acgtattttc aaaaaaaaaa aaaaaaaatg catatttatc ttagcaaaac
     9721 gacaatttaa atcgtcgttt ttttgtagta cgacgggcat gtcgtatatc tgaggtgtaa
     9781 gtcctcggtg ggcacctgct accggtgaac ccaatagcga ttcccaagcc tgactatcgt
     9841 gaggtagcag ggagaggaag ggatagcgaa atcgtggctc tacgaacagg aacgtgatag
     9901 taaggcgtat atagcggata aggaggcttc aaactctaaa gtccaaaaag gtagtcgtaa
     9961 cctatatgtg taaatcacga gagtaattga attcggacta aggtttgtgt gaaaaagata
    10021 aatctttcta gagtctaaag actctgcgtc agatttccta ttttcactgt aaccttttaa
    10081 cgtcctcata tcttgtataa acgaggaaag atgtacgact tatcccgtga ggtttcatga
    10141 gcgctgaaag cgtagtaaca acgaatcatg agaagtcagc cgagcccata gtagtgagga
    10201 aacttccgta atggaagtgg agcgaagggg tgaatactca aacagtctgg ggagagactg
    10261 tttgaggtct gtcgctagaa agagaaaacg acagatcgaa gtaatcctac ttcacttgtg
    10321 tctgtaaaat gagtggtctg atagaactgg actttgacac gta
//
LOCUS       DAVBIC010000065        10036 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.065, whole genome shotgun sequence.
ACCESSION   DAVBIC010000065 DAVBIC010000000
VERSION     DAVBIC010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10036)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10036)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10036
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.065"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            complement(103..1806)
                     /gene="ilvD"
                     /locus_tag="VQ664_001894"
     CDS             complement(103..1806)
                     /gene="ilvD"
                     /locus_tag="VQ664_001894"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HET2790001.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETSIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(2039..2971)
                     /locus_tag="VQ664_001895"
     CDS             complement(2039..2971)
                     /locus_tag="VQ664_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HET2790002.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSDSDIVVLEADLSSSMATNNLEK
                     DFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFASRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPVPVYQGGEDFSKGYIELRHGEDLVIVASGIMVAPSIRVADELSKLGYSV
                     GVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSALCELFSDDGITKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            complement(2968..3825)
                     /locus_tag="VQ664_001896"
     CDS             complement(2968..3825)
                     /locus_tag="VQ664_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HET2790003.1"
                     /translation="MILSKNREDGLRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDDNKKQLDGFTKDICNPGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEEKQMLTSVVER
                     LSQELEETE"
     gene            complement(3829..5175)
                     /locus_tag="VQ664_001897"
     CDS             complement(3829..5175)
                     /locus_tag="VQ664_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HET2790004.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATAMIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFVGGLVSMVIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFIKKPSATEE"
     gene            complement(5188..5472)
                     /locus_tag="VQ664_001898"
     CDS             complement(5188..5472)
                     /locus_tag="VQ664_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET2790005.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKLCEEKGLI"
     gene            complement(5476..7506)
                     /locus_tag="VQ664_001899"
     CDS             complement(5476..7506)
                     /locus_tag="VQ664_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HET2790006.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NSHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLIDQVVKDYYEKLQLVPIVNQLKVYLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKWYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKASSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYDDIKMIIKQED"
     gene            7698..8705
                     /locus_tag="VQ664_001900"
     CDS             7698..8705
                     /locus_tag="VQ664_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HET2790007.1"
                     /translation="MTEKLINSKPNGVFALILIELTIVLGIFIFIMGVGSENIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNDNDVNLEIGKKQISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            8708..8908
                     /locus_tag="VQ664_001901"
     CDS             8708..8908
                     /locus_tag="VQ664_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HET2790008.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            9060..9242
                     /gene="rpmF"
                     /locus_tag="VQ664_001902"
     CDS             9060..9242
                     /gene="rpmF"
                     /locus_tag="VQ664_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HET2790009.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKITKAASAE"
     gene            9258..9407
                     /gene="rpmG"
                     /locus_tag="VQ664_001903"
     CDS             9258..9407
                     /gene="rpmG"
                     /locus_tag="VQ664_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HET2790010.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(9899..>10036)
                     /locus_tag="VQ664_001904"
     CDS             complement(9899..>10036)
                     /locus_tag="VQ664_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HET2790011.1"
                     /translation="ESGSMATGWVTVSGKWYYTYNSGDLLVNTTTPDGYRVNANGEWV
                     G"
BASE COUNT         3252 a         2132 c         1626 g         3026 t
ORIGIN      
        1 caaaacactg ttttgaggtt gtggatagaa ctgacgaagt cagtaaccat acctacggca
       61 aggcgacgtt gacgtgattt gaagagattt tcgagtatga gtttattttt tacctgactt
      121 gtccatattc cagaagtctg tcacggctcc gcgtgaagca gatgatacga tgtgggcata
      181 tttaccgagg acaccacggc tgtaaagtgg tggcaaggtt gtttctgcct tgcgtttttc
      241 aagttcttct tcggatacgg ccatagaaat ttctttggta tcttggtcaa ccgtaacgat
      301 atcgccggta cggagatagg caattggtcc accatcctga gcttcaggag cgatatgtcc
      361 aacaaccaga ccataagtac caccagagaa acgtccgtcc gtcaagaggg ccaccttatc
      421 tccctgacct ttaccaacaa tcattgaaga aagtgatagc atctcaggca taccaggacc
      481 acctttaggt ccaacaaaac gaacaacgac tacatcgcca tcaacgattt catctgtcag
      541 aacggcctga atcgcatctt cttctgagtc aaagacctta gctggcccaa cgtgacgacg
      601 cactttaaca cctgatacct tggcaactgc accgtcagga gcaaggttcc cgttcaagat
      661 gataagcgga ccatccgcac gttttggatt ttcaagtggc atgataactt tttggcctgg
      721 agtcaagtct gcaaagtcag ccaagttttc agctacagtc ttaccagtac atgtgatgcg
      781 atctccgtga aggaaaccat ttgccaacaa atacttcata accgcaggga caccaccgac
      841 ttcgtagagg tcttggaaga catactgacc agatggtttc aagtcggcca agtgaggcac
      901 acgttcttga atcgtattga agtcctcaag tgacaagtca acatttgcgg catgggcaat
      961 ggcgagcaag tgaagagtgg cgtttgtaga accaccgaga gccatcgtta cagtgatagc
     1021 atcttcaaag gcttcacgag tcaagatatc tgatggtttg agaccaagtt ccaacatctt
     1081 aacaacagca cgtcctgctg cttcgatatc ttctttctta tcagctgatt cagctgggtg
     1141 agaggatgac cctggcaaac tcatccctag aacttcgata gcagttgcca tggtattagc
     1201 agtatacata ccaccacaac caccagggcc agggcaggca ttacattcaa gacgtttcac
     1261 gtcctcagct gtcatgtcac cgtggttcca ttttccgata ccttcaaaga cagaaaccaa
     1321 gtcgatatct ttaccatcaa gatttcccgg tgcaatagtt ccaccatagg cgaaaatagc
     1381 tgggatatcc atattagcaa tagcaatcat agatccaggc atgttcttgt cacagccacc
     1441 gatagcgacg aaggcatcca cgttgtgacc actcatagcc gcctcgatgg agtccgcgat
     1501 gatgtcacga gatgttagag agaaacgcat accaggcgtt cccatagcga tcccgtccgc
     1561 tacggtaatg gttccaaact gtacaggcca agcgcctgca gatttgacac cttctttagc
     1621 cagtttcccg aaatcatgca agtgaatgtt acatggtgta ttttccgccc aagtcgaaat
     1681 cactcccaca atcgatgttt caaagtcctt atctgtcata ccagtcgcac gaagcatagc
     1741 acggttaggt gatttaacca tgctgtcata aatgctactg cggtgacgtt tatctaattc
     1801 agtcatctta tccctcccat ttcagttttt actattatag cacaattttc gcatgaagaa
     1861 cagaataaaa ttcttgaatt ttcagaaaat tctatacaca tgtgaaatat ttaaaattaa
     1921 aaacaacaaa gcggattagt gcactttctg atgaccagaa tatgcttttt aatccgcttt
     1981 ctttaaataa cgtactgtaa tttttacaga aattctttca aataagtgta tttaacatct
     2041 atcttgcatt ataaatttct agaaccttct cttttatatt cgattcactc aaaccatact
     2101 cattaagaag ataatccatt ttccctactt gaccgaatct ttcttgaaca cccatccgat
     2161 gaatttttgt tattccatca tcagagaata attcacataa agcactgcca attccaccta
     2221 tctgattgtg gttttctaca gtaaatatag tttttccact taacattgtt tttatctgtt
     2281 ctggtatcgg tttgattcta aataaatcta tcacacctac tgaataacct aatttagaca
     2341 gttcatctgc aactcgaata cttggagcaa ccattatgcc agaagcaacg attacaagat
     2401 cttcaccatg ccttaactca atgtagcctt tagaaaaatc ttctccacct tgatacacag
     2461 gaactggagc ttttctaatt gttcgaatat attttagtcc ttttaagtct aatgtctggt
     2521 tcaatatttc acgaaattgg atatcatcag ttgcttcgaa aatgattgat ttaggaatta
     2581 aacgtaacaa tccaatttct tcaaatggca tatgtgttcc accattcatc tctgccgtta
     2641 ctcctgcatc tgatccaatc acagtggcat ccaattgtgc gtatccaaga gaaataaata
     2701 attgatcaaa tactcttcgt gaagcaaaag gaccaaatgt atgaagataa ggtctaaacc
     2761 cctgaataga caagcctgct gcaaggccga ccatttctgc ttccataatc ccaacattca
     2821 cataacggtc tccaaagtcc ttttcaagat tattagtagc catcgaactt gacaaatcgg
     2881 cttctaagac tactatatca gaatcacttt gattagcctc taaaaggaag tctctatata
     2941 catgccgtaa ttctttcgta cttctcatca ttctgtttcc tccaattcct gacttaatct
     3001 ttctacaact gaagttaaca tttgtttctc ctctacagta gggcgaagat gatgattgga
     3061 tttcatttct tccagctctt gaaccccttg acctttaata gtatctaata caatgcactt
     3121 aggtgatgaa ttatttgact gttttaattg gacaatccct tcataaattt ctctaatatc
     3181 tgaacccttg accctaatgg attcaaatcc aaatgctgaa aatttttcta cgaaatcacc
     3241 tggattacaa atatcctttg taaaaccatc taattgtttt ttgttatcat caacaaatac
     3301 aattaagttg gataactgtt gatgagaagc aaactgtata gcctcccaac attgtccctc
     3361 atttaactca ccatctccaa caatagcgta agtataaaag ggactctttc ttattctctg
     3421 accatatgca agtccagttg caacactaat tccttgtcct aaagagcccg ttgtcatatc
     3481 tatgcctggc gttagatttc tatcaggatg agacggtaat ttggttccat ttgtatttaa
     3541 agaatataag aattctttgt caaagaaacc attcaaatag agtgtactgt atagagctgg
     3601 tcctccgtga ccttttgata atatgaaata atctctatct cgtgctgcaa atatttctgg
     3661 agtcattggc attatttcac cataaagcac cgctaaaact tctacgatag acagacttcc
     3721 tccgtaatgt ccgaatccaa gatgattcaa tgttctaaga gtatttaatc ggatgttagt
     3781 cgcaaatttt cttaacccat cttctctatt tttacttaaa atcatccctt attcctccgt
     3841 tgcagatggc tttttaataa aggatactcc aaacataact gctagaataa gaacaagacc
     3901 aatcacaatg cctgcttgtg agccaaattg atttaacatt cctaaaataa ttcctgatag
     3961 accaaaatct gcatctgaga aagttgatcc ttggaaacca agtcctccca aaactggcat
     4021 taaaaagact ggaagaaaac tgattaaaat accttgtaaa aatgctccaa tagtggctcc
     4081 acgaacacca ccagatgcat tcccaatgac acctgcagtc gctccacaga agaaatgagg
     4141 cacaacacct ggtaagataa caaccgttcc tgaagcaatc ataattacca tacttactaa
     4201 accaccaaca aaactagaga taaatccaat tagaactgca ttgggtgcat aagtataaac
     4261 aatcggacaa tccaaagcag gttttgaatt aggtacaaga cgctctgaaa tacctttaaa
     4321 ggctggaaca atttcgccca aaataaggcg aacacctgct aaaataacaa atacccctgc
     4381 tgcaaattga cctgctaatt gtaaagcata aactagacca cttgtaccac tactgatttc
     4441 tttttctata tattctgacc ctgcaaagat agctacaata atgtaaataa ctgccatgga
     4501 taaagtaata ctaacagtac tatcacgtaa aaaagctaaa ctctttggaa atttaatgtc
     4561 ctctgttgat tttgatttgt caccgataag gctaccagta aaaccactca accaatatcc
     4621 caaagaactg aaatgaccta aagctacctt gtcatttcca gttaattgaa ccatatattt
     4681 ttgcacaaat gctggggaaa tactcataat aataccgagt gctaatcctc ctagtaagat
     4741 gagaggcaag ctagtaaagc cagcaactga taaaatgacc gcaatcatac atgccatata
     4801 tagagtgtgg tgccctgtta aaaaaatata tttaaatcga gtaaaacgag cgattaagat
     4861 attgaacacc atgcctgcaa acataatcat tgcagtagct gagccatatg ttgttaaagc
     4921 tacagctaca attgcttcat tattcggcac aacgccagat aaatgaaaag catgctcaaa
     4981 catggtacca aatggattta aagaattttg tacaattcct gcaccaccag atacaactaa
     5041 gaaaccaaca aaggtcttaa ttccaccttt aataatatca ggtaatttct tcttctgaag
     5101 aactaatcct aagattgcaa ttaaagctac taaaatagct ggtgtactaa caatatccaa
     5161 tatgaacttc atcatgacgc tagcctccta tataagtcct ttttcttcac aaagtttagt
     5221 aattaattct cgtagttcat ccatatcaat aatactattt aagatacgaa catctccaag
     5281 atgactagct gaatcagcta gatcacgacc aacaatccaa atatcagctg catttggatc
     5341 tgctccacct aaatcataat gttcaacttc tacatccgaa acattcaaat cactcaatac
     5401 agattcaata ttcatctgta ccataaaact tgaacctaat cctgaaccac aagctgtacc
     5461 aatttttaac attatctaat cctcctgttt aattatcatt ttaatgtcat catagttttt
     5521 tgatgatatt aaagtttgaa catgattttt atctcttaaa attgttgtta aatgtgacaa
     5581 agcctttaaa tgactctcat tatcaatggc tgcaatacaa atcaacaatc ttacctcttg
     5641 ttctggatta tccaataaat aaatcggttc ttccaaaact aacattgaca ttcctatttc
     5701 attcacacct tcatctggcc gagcgtgagg aattgctact cccttcccta aattaataaa
     5761 aggtccaaac tcttctactt tttgaatcat tgcctcaggg tagttctcag ttatcttatc
     5821 ttgatccaaa agcggtttag ctgctaaacg aatcgcctcc ttccatccta atttttgcga
     5881 actaacctga taggtttctt tggtaataag ttgttctagc actggtacaa tttcctttct
     5941 atcatttttt tggtaaagat aattctttaa cgccaatctt aattccaatt cttgtgtaat
     6001 aattccatat cttttgacaa tattcaggat ttgttcaatc tcaaaatctc catactctaa
     6061 attcggaaaa tcttttaaca ctagttctac tagttgtatt gcttgctctt cagtcatcat
     6121 aaccgaaact agataatttg gcttttctgt ctccaccttt atggtagaaa aaaccatatc
     6181 atagtcacta ctagctttca cctgtaaatc atcaatcttt gaggttccta taaactcaat
     6241 ttgaggaaat aatgctaata gattctcttt taacatcaat gaagaactaa caccattagg
     6301 acaaatgatt gctgctttat accatttttg aggcaaagta tctgctttct ttaaataacc
     6361 tccgaaatgg ataacaaaat atgctgtttc actatcaggt atgggattgt caatagcgtc
     6421 catcaagggc atcaaagaat ctttgactaa ttcaaataaa tcaggataat gttctttaac
     6481 atgcaataca tattcatttg aactaggtag gccgaacttt aatctatagt aagccggtat
     6541 aaggtggcgg cgaagatttt ctctcaatcc ttccctttgt ttaaaatgta acaaagaaat
     6601 atcttccatt ctacttataa tagcctctgt taattgatta aagtaaaccg gagcaacatc
     6661 tacttcacct tcaaagcaac ttgataataa aacggtgata tagcgataat catcctcaga
     6721 aaacaccgta tctataattc ccaaatcaac cactgtatcc aataaaatag tggttatatc
     6781 ttgaataaca ggagatacta atgtctctga aagacatact ctttcaacat ccctttgata
     6841 cctacacaga atgaatacta aaccgaaaag gtaaactttt aattgattaa caataggtac
     6901 tagctgtagc ttctcataat aatctttaac tacctgatca atcaaatcat aagttaatga
     6961 atacccccaa ctggataaaa cataatccaa accccaaatc cctatggagg attccagcaa
     7021 ctcactaacc atttgaaaag ctaagcggtg cttattccac tctgaaccgt gtaaagtata
     7081 accttttgct ctactgtacc ctagctccaa atcattatct aacataatct ttcttaatga
     7141 ttgaatatca gataaggttg tattcttact tactttcaaa aagtcttggt aatgactatt
     7201 cgatataaaa tctaatcggc aaaaagtgta aagatagatt aaagctaagc gagtcgactt
     7261 tggtaaaacc aattcatccg acttaataat atctgtcaaa gactgcttcg tacgatttga
     7321 taaactatag cgaccttgct ttttatccag cactatccct ttattagcta gataaggcac
     7381 taaataatct attccttctt tgacttcctt tataggtaag ctcaccttaa cagataattc
     7441 atataatgat agctcacaat gatccatcaa agtcatcaaa ataactagtg ctctataatc
     7501 aaacatttct cttcctttct aactacaatt atagtgtaaa aattataaga ataaaagagt
     7561 atttgagcac aatataatct caccttttaa aagaaattat tgggctgaaa gtttttagtg
     7621 attatttttc aactttctat tgactttata aattaaagtg atatcattta gatatcaaat
     7681 aacaggaggt cattcttatg actgaaaaac taatcaattc aaaaccaaat ggtgtattcg
     7741 cattgattct cattgagttg acaatcgtac ttggtatctt tatatttata atgggggttg
     7801 gttcggaaaa catttttgga attattatcg gacctttact aatcgtaatt gcaggtctag
     7861 ctcatgctgg tttaaaagtt gtcaaacctc aagaagctct ggttctgaca ctctttggta
     7921 actatacagg taccatcaaa gaacctggct tttactttgt caatcccttc agcgtagcag
     7981 tcaaccctgc aaaccacact cgacttggac aaagtggtga tgttagcaca aaatctcctt
     8041 ttttaggagc taaatcatca aatgacaatg atgtaaatct tgaaattggc aagaaacaga
     8101 tttccctcaa agtcatgacc ttgagcaatt ctcgtcaaaa aatcaatgat tgcttaggaa
     8161 accctgtaga aatcggtatc gcggtaactt ggagagttgt cgataccgct aaggcagtct
     8221 tcaacgttga taactacaaa gaatatcttt cattgcaatg tgatagcgcc ctccgtaata
     8281 ttgtccgcat ctatccttac gatgtgtctc ctaatgtgga tactacgggt gatgggcaag
     8341 cagatgaagg tagtctccgt ggctctagcg aaattgttgc taaccgtatt cgtgaagaaa
     8401 tccaaagtcg tgttgaggat gctggcttgg aaatccttga agcacgtatc acttacctag
     8461 cttatgctcc agaaattgct gccgttatgc ttcaacgcca acaagcatct gccattattg
     8521 atgcacggaa gatgattgta gatggtgctg taggaatggt tgaaatggca ctagaacggc
     8581 tcaatgaagg ggaattggta gaacttgacg aagaacgaaa agctgccatg gtttcaaatc
     8641 tccttgtcgt tctttgtggc aatcatgatg cacaaccaat tgtcaacaca ggaagccttt
     8701 actaaagatg gctgaagcta aaaaaaagca gatccccctt cgactctcaa caaagttata
     8761 cgctgcactc gcatcatggg cagaagacga ctttcgttca gtcaatgggc aaatcgaata
     8821 tctcctcaca gagtgtgtca agcaacggaa gaaagacgga aaatacgtat cagaaaccat
     8881 tgacgaacca tttgagattg atatttaaca ccttctcctg tctgccgtgt cggataggag
     8941 aattttttca tctttttttg tcaagtaact ttactttaca aaaaaaatgt gttatcctag
     9001 tatggttgat gaaaatcagt agattgaatc gaatataaat acctaaagga gaaatcaaaa
     9061 tggcagtacc tgcacgtcgc acttcaaaag cgaagaaaaa caaacgtcgt acacactaca
     9121 aagtaacagc tccatctgta aactttgacg aaactactgg agattactca cgttctcacc
     9181 gtgtatcact taaaggatac tacaaaggac gtaaaatcac taaagctgca tcagctgaat
     9241 aatagaaggg agataccatg cgcgtaaata ttacacttga acacaaagaa tctggtgaac
     9301 gcttgtacct tacttctaaa aacaaacgta acactccaga ccgccttcaa ttgaagaaat
     9361 actcaccaaa acttcgcaaa cacgttgtgt ttacagaggt taaataagca ttcaatacga
     9421 atcaatacag aagaaaaacg cttgatcagc gttttttctt tttgttaatt tcactacatt
     9481 gtaagggaaa tcattcgaat gactacattt ttcactacct tttttgaaat aagaatacgg
     9541 attcggacaa ttaaaagcaa gaggaactca aatgtaagtt ggggttcctt ttttgtatat
     9601 ttttcaaata acgcctctac actatttgta gcaaattcac caactacagt tgtatcttag
     9661 ttaaaataag ttagaatatg taagtgagta ccagatatac caagacatcg tcaccatcta
     9721 aggtatattc aaaatacaaa agttgaccaa ctagatttct gaatatcctt atatatccat
     9781 tcttaaaatt ggtttaaata gcgtagtctt ttaaactagt tttgagaatc caaaaaatct
     9841 tcctacatat gtaagaagat tttttagttc agaatgatta gatttagcta atggatacct
     9901 atcctaccca ctcaccgtta gcattgactc gatagccatc gggtgtagtc gtgtttacta
     9961 ataaatctcc tgaattatag gtatagtacc atttaccaga aactgtaacc caaccagtag
    10021 ccattgaacc tgattc
//
LOCUS       DAVBIC010000066         9472 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.066, whole genome shotgun sequence.
ACCESSION   DAVBIC010000066 DAVBIC010000000
VERSION     DAVBIC010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9472)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9472)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9472
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.066"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            150..686
                     /locus_tag="VQ664_001905"
     CDS             150..686
                     /locus_tag="VQ664_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HET2790012.1"
                     /translation="MKKAHVYAIPAIGAALIAALAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALAVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
     gene            737..823
                     /locus_tag="VQ664_001906"
                     /pseudo
     CDS             737..823
                     /locus_tag="VQ664_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(892..1107)
                     /locus_tag="VQ664_001907"
     CDS             complement(892..1107)
                     /locus_tag="VQ664_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HET2790013.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            1205..1525
                     /locus_tag="VQ664_001908"
     CDS             1205..1525
                     /locus_tag="VQ664_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2790014.1"
                     /translation="MRHKFQQVLNKIHDFLNGYDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFAKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            complement(1556..1894)
                     /locus_tag="VQ664_001909"
     CDS             complement(1556..1894)
                     /locus_tag="VQ664_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2790015.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(1906..2625)
                     /gene="trmD"
                     /locus_tag="VQ664_001910"
     CDS             complement(1906..2625)
                     /gene="trmD"
                     /locus_tag="VQ664_001910"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HET2790016.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            complement(2615..3133)
                     /gene="rimM"
                     /locus_tag="VQ664_001911"
     CDS             complement(2615..3133)
                     /gene="rimM"
                     /locus_tag="VQ664_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HET2790017.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKRYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            complement(3164..3952)
                     /locus_tag="VQ664_001912"
     CDS             complement(3164..3952)
                     /locus_tag="VQ664_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET2790018.1"
                     /translation="MKRFEVSTEIGSLSVTYQKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKNLDNLADAVYEVLEELGISEYILCAHSWSGI
                     LACKLLEKPIKRQTLVAIEPTTKKVMFADFSENPYPEMEEQMRLIDECGPELYFKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEEDFEDVSIEAHIPVFVFCQP
                     YREKEYRESEYWTSNTKLILGGNHHYLQWSESEKIAAIIRELSE"
     gene            complement(4529..4768)
                     /locus_tag="VQ664_001913"
     CDS             complement(4529..4768)
                     /locus_tag="VQ664_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HET2790019.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
     gene            complement(4788..5060)
                     /gene="rpsP"
                     /locus_tag="VQ664_001914"
     CDS             complement(4788..5060)
                     /gene="rpsP"
                     /locus_tag="VQ664_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HET2790020.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            5230..5439
                     /locus_tag="VQ664_001915"
     CDS             5230..5439
                     /locus_tag="VQ664_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2790021.1"
                     /translation="MLSVNTILEKFYKEHQVKPFISPERELDTWLLSPKPVPKRNMDL
                     LVDDSLAGDIILLWRIQFGTFTTET"
     gene            5918..6139
                     /locus_tag="VQ664_001916"
     CDS             5918..6139
                     /locus_tag="VQ664_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2790022.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEEVEDFQDDDEIPTII"
     gene            6222..7025
                     /locus_tag="VQ664_001917"
     CDS             6222..7025
                     /locus_tag="VQ664_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HET2790023.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQSSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIDGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(7081..8622)
                     /locus_tag="VQ664_001918"
     CDS             complement(7081..8622)
                     /locus_tag="VQ664_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET2790024.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMEMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQAKNLQIGY
                     DLPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHEPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(8624..9106)
                     /locus_tag="VQ664_001919"
     CDS             complement(8624..9106)
                     /locus_tag="VQ664_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HET2790025.1"
                     /translation="MMKKTYNHILVWGVIFYSICIVYFCFTPQEQSTVGVGTPDIQHL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNILNVFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKIRN
                     "
     gene            complement(9106..>9472)
                     /locus_tag="VQ664_001920"
     CDS             complement(9106..>9472)
                     /locus_tag="VQ664_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="50S rRNA methyltransferase"
                     /protein_id="HET2790026.1"
                     /translation="KLFAAIEYYIETTNRRVTFEYIMLNEVNDGVEQALELAELLKNI
                     KKSSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGGNCVVRQEHGTDIDAACGQ
                     LLFNTMKRDRQKAVAAVNP"
BASE COUNT         2796 a         2028 c         1698 g         2950 t
ORIGIN      
        1 attttcgaat caacaaaaaa attatccaac ttgactagtc acgaaaatcg gctgttacag
       61 tttttgttac cttgttttta aaaaatggtt gacatcgact cctatatgag tataatagtt
      121 atcatacatt agaaaagagg ttaactattt tgaaaaaagc tcacgtttat gctatccctg
      181 ctattggggc tgctctcatt gctgctttgg cacaaatcag tcttccaatt ggacctgttc
      241 ccttcactct gcaaaacttt gcaatcggct tgattgctac tgtctttaga ccgagagagg
      301 ctgtactttc tgctggactc tatcttcttc taggtgctat cggtcttcct gtctttgcag
      361 gaggtggagc tggttttcag gctttagttg gccctactgc aggctatctt tggttttatc
      421 tcgtttactc tggacttact tcctctctaa ccaacagcaa gagtggtgtt gttaagattt
      481 ttcttgcaaa cctcttgggt gatgcccttg tctttgtcgg cgggattctc agcttgcatt
      541 tcctagctgg aatggcattt gaaaaagctc ttgctgtggg ggttcttccc tttatcattc
      601 cagaccttgg caaacttctg gctattagtt ttattagccg tcccctactt caacgcctta
      661 aaaatcaggc ttactttact aactaaaaaa ggatatcgag ttatcatgac tcaatatcct
      721 tttcttttat tttgaaaact tatactcaat gaaaatcaaa gagcaaacta gaaagctagc
      781 cgcaggctgc tcaaaacact gttttgaggt tgtggatgaa actgacgaag tcagtaacca
      841 tacatacggc aaggcaaagc tgacgcggtt tgaagagatt ttcgaagagt attagttgcc
      901 tttaaaggca tccaccatcg tttgaaattc ttcatttgag agagtaatcc ctttgcccat
      961 tttagtatgg tctggactcc aagcacgaat atcaaacttt gcaggggcac cattaaagct
     1021 cacacggtta atttccttgg tccaaccttt ttcgttttca gaaagagtca acaagtgctc
     1081 ttcgatttca aatgtaaatt ctgccatttt cttctccttt tttagtttca ttagtttatt
     1141 cgtaaaatct tgtagatttt aggaaaattt tatataatat tgatataaaa gaagggaggc
     1201 caatatgaga cataaattcc agcaagttct aaataaaata catgattttt taaatggata
     1261 tgaccaacct gaccagactg aaaccaactc ccttacagcc actattgaag aggctatcca
     1321 gaaacaaacc gctgttcacc ttatcttgtc tgagacaagt tttacaggtg atatcatcaa
     1381 atatgatcag caaggccagc aaattatcgt gaaaaatttt gccaaaaatg tgagccggat
     1441 tatccgtata agcgatattc aacgcctgcg atttgtcccc tcaactgtcc aaacagccca
     1501 aaaaaataga tttaagaaag agtgagatgt agttgcttca tcccactctt ttttcttagc
     1561 gaatttgttc aaaatgtaaa tgaactgcaa tatgatctcc ataaccactt ctttccaagt
     1621 cacgttgtaa acgataggaa atgtagtgtt ctgcaatggt aatgtaacct gcgcccaata
     1681 aacgatgttc aaccatagat tgaatcatac tgatagtcgc acgttccacc ttggcttctt
     1741 gtaaatccaa aactaccttc ttagtgactt gagcaagatt ttgacgcaaa tcatctgtca
     1801 aaacataaac agtttgggct gccttcaaga tggcttggta aatcttatct ggattaaatt
     1861 cagcaatttc gccattacgt ttgattactt gcataggttt ctcctttatt ctttgttttc
     1921 tttgatttct gccagcattt tttcttcttc tactgtcagt tgataatgtt caagtaaatc
     1981 cggtctgcgc tcgtaggttt tctttaaact ctcgtacaat cgccactgac gaatcttttc
     2041 atggtggcca ctcatcaata catctggcac gaccatgcct cgataatcat agggacgtgt
     2101 gtactgagga tattctaaaa gacctgaaga aaaactatca tcttggtggc tagactcctt
     2161 gccaatcact tctggaatca ggcgaactgt agcatcaatc atggtcatag ctgccaattc
     2221 tccaccagtg aggacatagt cgcctaggga aatctcatct gttaccaagg tcttaatgcg
     2281 ctcatcataa ccctcatagt gcccacagat aaagattagc tcttcctctt gagccaaatc
     2341 ttcagcataa gcctgatcaa actgctttcc agcaggatcg aggagaataa cgcgcggatt
     2401 tttcttttca atagcatcaa aggaatcgaa aataggttgt gctctgagca acatgccctg
     2461 accgcctccg tagggctcat catctacatg acgggccttt tcagcatttt ctcgaaaatt
     2521 atgatactgg atatccaaga gccctttttc tcgagccttt ccaacgattg agtgctccag
     2581 tggagaaaac atctctggaa agagggttaa aatatcaatc ttcatcgtct aacccttcta
     2641 agatttccac atcgacccgt ttatttggaa tatcaacatt gagaaccact ggtgggatat
     2701 aaggtaaaag caaatcacgt ttgccttttc gtttgaccac ccagacatca ttagcacctg
     2761 gttgcaggat ttccttgatg gttccaacca agctatcacc ctcatagact tccaaaccga
     2821 taatctcgtg atagtaaaat tcaccatcgt ctaggtcatt caaatcttcc tcagcgacct
     2881 tgagactata tctcttgtac ttttcgatag tattgatatg gtacatatct ttgaatttaa
     2941 taatgtcaaa gttcttctgt ttacggtggc tagcgatggt cactgtttgg acaaactgat
     3001 ctttttcatc aaacaaagcc agctcagctc cttttttaaa ccgttcttct gcaaaatccg
     3061 tcacagacaa gactcgcatc tcaccctgta atccctgcgt attaacgatt ttcccaacat
     3121 taaagtagtt catcttgtct cctgtaatct ccttttttcc atcttattct gacaattctc
     3181 gaataatagc cgcaattttt tccgattctg accattgtaa ataatggtga ttccctccta
     3241 aaatgagttt agtattggaa gtccaatatt ctgattctct gtactctttt tctctataag
     3301 gctgacaaaa aacaaataca ggaatatgag cttctataga tacatcctca aaatcttcct
     3361 cagtaatctc tccagatatc tgaaattctg gatcttgatt ttccaactct aagccttttt
     3421 cttgcattaa ttcccagatt tttttattcg tttcaggact aaatgttgct tgagttaagt
     3481 tcttaaaata aagttcagga ccacactcgt caatcagcct catctgctct tccatttctg
     3541 gataaggatt ttctgaaaaa tcagcaaaca tgactttttt agttgtcggt tcaattgcta
     3601 ctaaagtctg acgcttaatt ggtttctcga gtaatttgca agctaaaatt ccactccaac
     3661 tatgtgcaca aagtatatat tcagaaattc ctaattcttc aagtacttca taaaccgcat
     3721 ctgcaagatt atctagattt tttccagctt ggtcatgaat cggactccta cctgtgttcg
     3781 gaaaatcaat tgtcaaataa ccaattgtag gaggaggttt ttcaagtata agtgaaaaat
     3841 tttcataact tggtagcaaa cctgctccgt ttagacaaac tagcactttc ttttgctttt
     3901 gataagtaac agagaggcta ccaatttctg tagatacttc aaacctcttc ataaagaaat
     3961 ccactcattc tatataatga attattaaaa atccttatct tttattttat cacgttccaa
     4021 ggattttctc aagttggagg aaggggacaa catctctact ttcccttcaa aaatccttcc
     4081 aaatcatgtt tatgttggta attaacggct gcggttttgt ctttctcaaa gacagtcttg
     4141 gtaaggtcaa tatgattaat agctacgatt gcgacggtgt agtaaatgat atcagccagt
     4201 tctctggcaa gttcctcgtt cgaatcctat cccttctttt cgaccagagc gcctattcaa
     4261 aacctcggct acttctccga cttcctccac taacttcata aagagacctt catcagtccg
     4321 agactgctgt taatgttcga ttaagtagtc ttggaattgc ctaaacgttc aatcttttat
     4381 agtatattga aactagaata gtacaccttt acttctaaaa cattgttaga aatcgatttg
     4441 actgtcctga tcgatttgtc ctgttcttgt ttcattttac tatatcttct attccacaca
     4501 aaaaagcgag acatccgtcc cgcccttctt atttttcgtc aataacgatt cttacttttt
     4561 tgtattcagt tgggacagag tagacaatcg ttcttatcgc agaaatagtg cgacccttac
     4621 gaccgattac acgacccaca tcgctttgat caagattcaa atgatattcc aaaaattctg
     4681 gtgtatcctc aatcttgata gttaaggcat ctggttgtga aattaagggt ttcacaatcg
     4741 caataatgag attttcaatc gtatccatct gtcaacctac tttaaactta ttttgaaaat
     4801 ttagaatcgt ggaatttttt caatacgcct tcttttgaaa ggatgttacg tactgtgtct
     4861 gaaggttgag ctccattagc caaccatgca agaacgcggt cttctttcaa agttacttgg
     4921 ttttcagcaa caagtgggtt gtaagttcca actgtttcga tgaaacgtcc gtcacgtggt
     4981 gaacgtgaat ctgctacgtt gatacggtag aaaggttttt tcttagaacc catacgagtc
     5041 aaacggattt taactgccat ttttaaagtc tcatttcttt aattttttat ttcggtgaaa
     5101 tagctgagct atttagcaca tgttctatta tagcagattt ctggcatgtg tcaagaaaaa
     5161 aacttgacag actataaatt tcttaaagta tttagaaatt tgttagaata ggaaataaat
     5221 gtttgaaaga tgctatccgt gaatactatt ttagaaaaat tttataaaga acaccaagtc
     5281 aaacccttca tatcgcctga acgagagttg gatacttggc ttctaagtcc caagcccgtt
     5341 cccaagcgaa atatggactt attagtagat gattcactag caggagatat cattttacta
     5401 tggagaatcc agtttggtac ttttaccact gaaacatgat tttaaaaact cccattcgaa
     5461 tatgattcaa aattcgctta gaatcaatgt tttcccgctt tttcaaaaaa taaattttca
     5521 tctaatttaa ataactttca attaagtgtg aattttgctt aaaatcatta aaaagcaccc
     5581 catggtgtga accatgaagt gttgtaaatg ctgtgttgta gctagttctt agcgtttaga
     5641 gaactggcta gctttacgag ctttcttaag atctggtttc caaaatactt tgagtacact
     5701 tatggtattg atgcccctaa acatctaaaa actctggtag aaaaagggta tgctcttgtc
     5761 gaaacttctt ttgactcact tgaccatcta aataatacca tgaaaaagaa tatcctgaag
     5821 aagaagggag ttactggact ttctaaaatg aaatcttgcg acctggatca agcccttcat
     5881 gagcattttt cagaagaaga attagctggt cactttcatg tccttctatg gactttttta
     5941 caatggcatt gctatcacac ccaataccta tctaagcgcc tggttcgtaa actttattgc
     6001 agctcttcct ctaaatttcc taattgttga accaattgcc cgttttatac taagttcttt
     6061 tcagaaacca tttactgggg aagaagttga agaagttgaa gattttcaag atgatgatga
     6121 aatcccaact attatctaag ccagttctgt aaactactaa tatttgaaat ccacttcttt
     6181 ttagggtaca atggtataaa tgaatttttg agaggatcag aatgaaaaaa ctagcaaccc
     6241 ttcttttact gtctactgta gccctagctg ggtgtagcag cgtccaacgc agtctgcgtg
     6301 gtgatgatta tgttgattcc agtcttgctg ctgaagaaag ttccaaagta gctgcccaat
     6361 ctgccaagga gttaaacgat gctttaacaa acgaaaacgc caatttccca caactatcta
     6421 aggaagttgc tgaagatgaa gccgaagtga ttctccacac aagccaaggt gatattcgca
     6481 ttaaactctt ccctaaactc gctcctctag cggttgaaaa tttcctcact cacgccaaag
     6541 aaggctacta taacggtatt accttccacc gtgtcatcga tggctttatg gtccaaactg
     6601 gagatccaaa aggggacggt acaggtggtc agtccatctg gcatgacaag gataagacta
     6661 aagacaaagg aactggtttc aagaacgaga ttactcctta tttgtataac atccgtggtg
     6721 ctcttgctat ggctaatact ggtcaaccaa acaccaatgg cagccagttc ttcatcaacc
     6781 aaagctctac agatacctct tctaaactcc ctacaagcaa gtatccacag aaaattatcg
     6841 aagcctacaa agaaggtgga aaccctagtc tagatggcaa acacccagtc tttggtcaag
     6901 tgattgacgg tatggatgtt gtggataaga ttgctaaggc cgaaaaagat gaaaaagaca
     6961 agccaactac tgctatcaca atcgacagca tcgaagtggt gaaagactac gattttaaat
     7021 cttaaaaacc aaaaaaatac agtatccaca ttcggtactg tatttctttt actctcattc
     7081 ttaagttaaa ttattaaaat cccatatttg gtctatccag ccttcataaa agtctggctc
     7141 gtggcagacc ataaggatag atcccctata ttctttgaga gcgcgtttga gctcatcctt
     7201 tgcatccaca tccaaatggt tggtcggctc gtccagcact aaaacgttgt tttcacgatt
     7261 catcaagaga cagaaacgaa ccttggcttg ctctccccct gataatactt gaatctggct
     7321 ttcaatatgt ttggttgtca aaccacaacg ggcaagggct gcacggactt ctgcttgatt
     7381 aagggcagga aaggcattcc agacagcttc aagaggagtt tggcgattac cgccttctac
     7441 ttcctgctca aaataaccaa gttctaaata atctccacgc tccacttccc cagcgattgg
     7501 cgagataatg cccaagagac tcttcaagag agttgttttt ccaataccat tagcaccaat
     7561 aatcgcaacc ttttgattgc gttcgaaggt aagatttaaa ggcttagtaa gaggaaggtc
     7621 gtaaccaatt tgcaagttct tggcttggaa gataaagcgc cctggtgtac gagctggttt
     7681 gaaatcaaag gatggttttg gtttctcact ttggagttcg ataatatcca tcttatccaa
     7741 tttcttttga cgagacatag ccatattacg agttgcaaca cgggctttat tacgagccac
     7801 aaagtccttg aggtctgcaa tctctttctg ctggcgttcg taggctgcct ctagctgaga
     7861 tttcttcata gcataaactt cttggaactg gtagtagtca ccagagtaac gcgtcagctg
     7921 ttgattttcc acatgataga caatattgat aacgtcattg aggaatggaa tatcgtgcga
     7981 aatgagaaca aaggcattct catagttttg gagatagcgc ttgagccaat caatatgctc
     8041 agcatccaag tagttggtcg gctcgtccaa cagcaagata tcaggctttt caaggagaag
     8101 ttttgccaaa agcaccttgg ttctttgccc acctgacaaa gaagttacat ccgtatccat
     8161 gccaaagtcc ataacaccaa gagcacgcgc tacttcgtca atcttagcat ccaaggtata
     8221 gaaatcacga ctctccagac ggtcttgaag ttctcctact tcttccatga gagcatcaac
     8281 atccgcaccg tcttcagcca tttccatata gaggtcattg atacgagctt cagctttgaa
     8341 aagctcatca aaagccgtac ggagaacatc acgcaccgac tgtctttcag caaggacaga
     8401 gtgctgatcc aagtaaccag ccgtcacata tttggaccac tcaacctttc cttcatctgg
     8461 cagcatttta ccagtcacga tactcataaa ggttgatttt ccttcaccat tggcaccgac
     8521 caggccgata tgttctccct tgaggagacg gaaggacaca tcttcaaaaa ttgcacggtc
     8581 accaaaaccg tgactcagat ttttaacttc taaaatactc attttaattc cttatcttgt
     8641 ttttatgtaa tcgtttataa aggagccaag ccagatagcc acccaaagtg ttggtccaca
     8701 aatcatcaat ctcaaagacg cgattgaaat caaagaaaaa gtccaagatt aattgcgtac
     8761 actcgattcc aagactcaca agaaaactaa aaagaaggac cttttttgtt ttccgcaaat
     8821 ttggaaatag ataaaggagt tggaaaatca gaggaaaaaa caagaagaca ttgaggatat
     8881 tttgtaaaaa aatccaacat aattgtccaa tgtcactcac ttcgcccagt ttccagagag
     8941 aattgaaagg agtcaaaaga aaaaccaggc gtccaagatg ctgaatatct ggagttccca
     9001 ctcccacggt agattgttct tgaggagtaa agcaaaaata gacaatgcaa atgctataga
     9061 aaatgactcc ccagaccaaa atatgattat aagtcttctt catcattaag gatttaccgc
     9121 tgcgactgcc ttctggcggt cacgtttcat tgtgttaaag agcaattgtc cacaagctgc
     9181 gtcaatatct gtaccatgct cttgacgaac cacacagttg cccccttttt tcttaagcgt
     9241 atcatagaaa gccaacacgc gctctttggg actacggcta tattggtcat gctcactaac
     9301 tgggttataa ggaatcaagt ttacataaga cgatttcttg atgttcttga gcaattcagc
     9361 caattccaag gcttgttcca caccgtcgtt gacttcatta agcatgatat attcaaaggt
     9421 tacacgacgg tttgttgtct caatgtagta ttcaatagca gcaaagagtt tt
//
LOCUS       DAVBIC010000067         9077 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.067, whole genome shotgun sequence.
ACCESSION   DAVBIC010000067 DAVBIC010000000
VERSION     DAVBIC010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9077)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9077)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9077
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.067"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            complement(135..1103)
                     /locus_tag="VQ664_001921"
     CDS             complement(135..1103)
                     /locus_tag="VQ664_001921"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HET2790027.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVEVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
     gene            complement(1248..2063)
                     /locus_tag="VQ664_001922"
     CDS             complement(1248..2063)
                     /locus_tag="VQ664_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HET2790028.1"
                     /translation="MKKSSILFIFILLLCIGLQYETIYYTDGSRSGAEYGLMGVSIFL
                     ALFYMIPALYFLFRIGKKWELPKKVLILSLLGGMFLSGWLSSFTNTYIHDLLGVLFPD
                     SPFLNAFESAIVAPLVEEPLKLLPLVFVLALIPVRKLKSLFLLGIASGLGFQMIEDIG
                     YIRTDLPEGFDFTISRILERIISGIASHWTFSGLAVVGVYLLYRAHKEQKVGKKQGLI
                     FLGLALRTHFLFNSPFVELETELPLAIPVVTAIALYGFYHAYCFVEKHNELMT"
     gene            complement(2088..2585)
                     /locus_tag="VQ664_001923"
     CDS             complement(2088..2585)
                     /locus_tag="VQ664_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HET2790029.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     TVVEL"
     gene            complement(2658..4019)
                     /gene="radA"
                     /locus_tag="VQ664_001924"
     CDS             complement(2658..4019)
                     /gene="radA"
                     /locus_tag="VQ664_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HET2790030.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MSVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPKNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            complement(4033..4548)
                     /locus_tag="VQ664_001925"
     CDS             complement(4033..4548)
                     /locus_tag="VQ664_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HET2790031.1"
                     /translation="MKIIFVRHGEPDYRELEERSYIGFGIDLAPLSEMGRQQVQKLSK
                     NPLLSSAEIIVSSAVTRALETASYVVCATGFPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            complement(4550..4993)
                     /locus_tag="VQ664_001926"
     CDS             complement(4550..4993)
                     /locus_tag="VQ664_001926"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HET2790032.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAADGVRTGGFGSTGH"
     gene            complement(5050..5147)
                     /gene="ffs"
                     /locus_tag="VQ664_001927"
     ncRNA           complement(5050..5147)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VQ664_001927"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(5180..5647)
                     /locus_tag="VQ664_001928"
     CDS             complement(5180..5647)
                     /locus_tag="VQ664_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HET2790033.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYDILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK"
     gene            complement(5848..7134)
                     /locus_tag="VQ664_001929"
     CDS             complement(5848..7134)
                     /locus_tag="VQ664_001929"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HET2790034.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGIGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGARNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            complement(7365..7601)
                     /locus_tag="VQ664_001930"
     CDS             complement(7365..7601)
                     /locus_tag="VQ664_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecX"
                     /protein_id="HET2790035.1"
                     /translation="MLQKIYEQMTNFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCRRDFIVYHYRVAYRLYLEKLVMNRGFISC"
     gene            7867..8664
                     /locus_tag="VQ664_001931"
                     /pseudo
     CDS             7867..8664
                     /locus_tag="VQ664_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436304.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(8699..>9077)
                     /locus_tag="VQ664_001932"
     CDS             complement(8699..>9077)
                     /locus_tag="VQ664_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HET2790036.1"
                     /translation="RGKVSGRRYQRISLVAGLTNGELIAPMTYEEMVTSDFFEAWFQK
                     FLLPTLTTPSVIIMDNARFHRMGKLELLCEEFGHKLLPLPPYSPEYNPIEKTWAYIKK
                     NLKKVLPSCNTFYEALFSCSCFN"
BASE COUNT         2907 a         2161 c         1459 g         2550 t
ORIGIN      
        1 tgatgacgta cagtcatatt tcttctcttt ttattatatc acagttttaa atctagcttt
       61 actagattca ccgctactat ctatttattc ggaaaaaaga cgaaaaaacc tgagaatcat
      121 ctcaggcttg gtcattaaat ttttttctca atatcgaaaa gtggagaaag tggtcgtttt
      181 tcatgaatac gtacgatagc atcccctagg agatgagcga ttgaaatctg ctcaatctta
      241 tcaatcaaac gctcttctgg cagatagatg gtatccaaaa caaccaattt cttaatagct
      301 gatttttgga tattgtccgt agcaggacca gaaagaactg ggtgcgtaca gcttgcatag
      361 acttcaacag caccagcttc cgcaagagca tctgccgcat gacaaatcgt tccagcggta
      421 tcaatcatat catcaatcaa gatacaagtc ttgccttcaa ccttaccgat gatgttcata
      481 acttcactag tattcatctt atcaacgcta cgacgtttat caataatagc gatagatgtt
      541 ttcaaaaatt ctgccaactt acgagcacga gtcacccctc catggtccgg gctgacaacc
      601 acatagtcag aaccaaccat accacgacgc tcaaaataat ctgcaatcag aggagcaccc
      661 atcaaatgat ccacaggaat atcaaagaat ccttgaattt gcgcagcatg caagtcgatg
      721 gtcaataaac gatccactcc agctacttca agcatatttg cgacaagttt tgaagtgatt
      781 ggctcacgcg ctctcgcctt tctatcctga cgtgcatacc catagtaagg catgacaaca
      841 ttgacagatt ctgcactcgc acgcttcaaa gcatctacca taatcaaaat ttcaagcaga
      901 ttgtcattta caggcgaact agttgattgt aggataaaga cgtgtttccc acggattgat
      961 tcttcaatgt tgacctgaat ctctccatct gaaaattggc gaacacttga tttccccaac
     1021 tctatcccaa tctcctgcgc cacacgttct gccaattctt tattagaaga aagggcaaac
     1081 agctttaaat cagaaaaaga catgatttcc tccggtatat atgtatcgct tgtgcttttc
     1141 acaagatttt ccatctacca ttgtagcgct ttttgcacta tttttcaatc aaaaataaaa
     1201 gaagggcacc atatttgtac ccttgcatca ttcttttgaa aaatattcta ggtcatcaac
     1261 tcattgtgtt tctcaacaaa gcaataagca tgataaaaac catagagagc aatagccgta
     1321 accactggaa tcgctaaagg caactctgtt tccaactcca caaaaggaga gttaaacaag
     1381 aagtgagttc tcaaggctaa acctagaaaa ataaggccct gtttcttgcc aaccttctgt
     1441 tctttatggg ctctgtaaag caagtaaaca cctactacag ctagacctga aaaagtccag
     1501 tgagaggcaa ttcctgagat gatacgctct aaaattcgcg aaatagtaaa gtcaaagccc
     1561 tctggcaaat ccgtacgaat ataaccaata tcctcaatca tttggaatcc caaaccggaa
     1621 gcaattccaa gtaaaaacaa agattttaat tttcgcacag gaatcaaagc caaaacaaaa
     1681 acaagtggca ataatttcaa gggttcttct accaaaggag ccacaatagc actttcaaag
     1741 gcatttaaaa atggactatc tgggaaaaga acccccagta aatcatggat ataagtatta
     1801 gtaaaactag acaaccagcc tgaaaggaac atccctccca ataaagacag aatcaaaacc
     1861 ttctttggca attcccattt tttcccaata cggaagagaa aataaagagc cggaatcatg
     1921 taaaagagag ctagaaagat agaaactccc attagtccat attccgcacc tgacctcgaa
     1981 ccgtccgtat agtagatggt ttcatactgt aaaccaatac atagcaataa aataaaaata
     2041 aataaaatac tgcttttctt catacacttt ctttctaaat gaagtattta taattctacg
     2101 actgtcatac ttcctgtatc aacattgtaa atggcaccag agataatgac atcgtctggt
     2161 attaggggag actcgataag cagttgcata tcctcgcgta cactctcttc tatatcttgg
     2221 aagggcaaga agtcctggtc tgacacatct acacctaatt cctcttttaa atactcctga
     2281 aaaggttcat tttcaaaggt ctgagcacca cagtctgtat ggtgcaatac cacaatctct
     2341 cttgtcccca tttgttgctg ggaaataact agcgaacgaa tcatgtcttc agtcactcga
     2401 ccacctgcat tccgcaagat atgagcatcc ccaagtgcca agcccagagc ttgcgcaacg
     2461 tgcagacgag agtccataca ggtcacaata gctactcttg ttttgggttt aagtggcaga
     2521 tttaactgcc catgtagggc aacataagcc tgattagctt gcataaactg ttcaaaatac
     2581 gacacgattc cctccttgaa aatttgatag tcaaatattt ctcctatctt atcattttta
     2641 agagaatttg tcacggatta tgcaaagacc tttttcaaaa cttcctgaat cgttgtcacg
     2701 ccaatgacct gaatttcctt aggcagagtg attcctgtca aggaattctt aggtacataa
     2761 atcttagtaa agcccagttt agcagcttcg ttgatgcgtt gctcaatacg attcacgcgc
     2821 cgaatctctc ctgtcaagcc cagttctccg acaaaacatt cctgaggatt agttggcttg
     2881 tctttgtagc tcgaagcaat agcaactgca acagccaagt caatggcagg ttcatccaat
     2941 ttaacaccac cagcagattt gagataggca tcctgatttt gcaagagaag ccctgcccgt
     3001 ttttccaaaa cagacataat caagctagca cggttaaaat caagtcctgt cgtagtacgc
     3061 ttggcatttc caaacatggt cggtgttacc aaagcctgaa cctccgccaa aatcggacgc
     3121 gtcccttcca tggttacaac gatggaggaa ccagtcgccc catccaaacg ctcttctagg
     3181 aaaacttgac tcggattgag tacctcaacc aagccgcccg actgcatctc aaaaatccca
     3241 atctcattag tggaaccaaa acgatttttg accgctctca aaatacgaaa ggtgtggtga
     3301 cgctcccctt caaagtaaag caccgtatcc accatatgct ccaacatacg aggcccagcc
     3361 aaggttcctt ctttggtcac atgacctacg ataaagatgg caatgttatt ggtcttggcc
     3421 aactgcatga gttcagcggt cacttcacgc acctgagaaa cagacccctg cacccctgaa
     3481 atctcaggag acatgatggt ctggatggaa tcaataatga gaaagtctgg ctggatacgc
     3541 tccacttctg cacgaacact ctgcatattg gtctctgcat agagataaaa ctcactatca
     3601 atatcaccta agcgctctgc acgtagttta atctgctggg cagactcctc cccactgaca
     3661 tagagaactg tccccacttg ggacaactgg gttgagactt gtaggagaag agttgatttc
     3721 ccaatcccag gatccccacc gatgaggacg agacttcctg gtaccactcc gcctccaagc
     3781 acacggttga attcctccat ctccgtcttg gttcgattga cattgatgga agtcacctca
     3841 gctagtttca tgggcttggt tttctcacct gtcaaggaca cacgcgcatt cttgacctcg
     3901 gcaacctcaa cctcttccac aaaagaagac caagacccac agttggggca acgtcccaga
     3961 tatttagggg aattataccc acaattttga catacaaatg tcgctttttt ctttgcgatg
     4021 acaaacctct ttctatatct ctaactcaca ctcaatcact tggcaaaaat caatcttctc
     4081 atttggcaca aactggcgca tgagcattcg atgagcaaca actaccacag tctgatgttc
     4141 tcgatactta gacatacatt ctagaaaccg agacttcatt tccgtagctg tctcatattg
     4201 aataggacta ttaggaagca actccccctt gttttctaaa aacagtcttc tagctgtttc
     4261 aaagttttct attcctgttt tatagacctg ccattcatgt aataaaggct ctactcttaa
     4321 aggaaaaccc gtagcacata ccacatacga agccgtttct aaagctcttg tgactgcaga
     4381 agatacgatt atttcagctg acgagagtaa aggatttttg ctcaatttct ggacttgctg
     4441 ccgtcccatc tcagacaagg gtgccaaatc tatcccaaat cctatataag aacgctcctc
     4501 taactcacgg taatctggct ccccatgacg tacaaagata atcttcattc tagtgccctg
     4561 tcgatccaaa tccaccagtt cgaacgccat cagccgcatc tccatctgca attaagaaag
     4621 tagcaaaaac agcctggaca atacgctccc caacttcaag aacaacctct tggtctgtga
     4681 tattcttcat ctgcgcaaaa atatgccctt catttccagg atttccataa taatccccat
     4741 caatgactcc aactgagtta attaaaacca agcccttctt acgaggattt gaagaacgat
     4801 catagaggta gagaacctca gtcggctgca tataagcctt aacccctgtc ggaaccaaga
     4861 caatctctcc tggcgcaaca actgtacgca cagcaacctt taagtcgtaa ccagccgcat
     4921 gcgctgtctc acgcttgggc aataaatttt catctgtaaa actcgaaacc aattcaaaac
     4981 cacgaatttt cataattttc tcttttctat tatcatttat tctagattat tctatcttat
     5041 ttattcggaa aaagcacgaa aaaaagagca cacaattcaa atcgcttagg gctgctggat
     5101 tcctcccctg acccgcttca cgcagaactg ttgctccact atttattata tcacattcct
     5161 attcatttta aaagcaaaat tattttttcc gtctatttct aaaaaaatcc tgcatgatag
     5221 ctgcgcattc atcttccaaa attcctattt caacctccac acgatgatta agacgctcat
     5281 ctgtcaagat atcgtacaaa cttccagcag cgccaaattt ctggttttta gccccataga
     5341 ccacatttgg aatgcgggca agcccaatcg ccccactaca catgacacaa ggttcaatgg
     5401 tcacaaaaag tgtgcaatcc agcaagcgcc agctctcctc actcaagttc gcatcctcta
     5461 tagccataat ttccgcatgc ataaccgctc gctgtaattc ctcacgcgca ttatgcccac
     5521 gaccaatgat ttccccatct ttgacaatca cacaaccaat tggaatttca tcgtgttcaa
     5581 gagcaatctc agcctctctc aaagcctccc tcataaagac ttctttttct tcaagcgtat
     5641 aatacatctc ttttctcttt tcctacttat cgattttatt attatatcat gaatcccaac
     5701 acaaaaaaag ccaccgaatg cggtgactct atagggagat tattatgaaa aagaaaagtt
     5761 taggatattt gttacaacaa gttaggaggt cttcttgtaa ctgtctatag tatacccgac
     5821 ctatcttaaa caaatcttaa aaatctctta ggaccaaaca ctttctaaaa tatttgtttg
     5881 ttcacgacca ggacctactg agaaagtaga aatacgaacg ccaaccaatt cactcacacg
     5941 acgaacatag ttacgcgcat tctcaggaag atcttccaaa ttgcgagctc cggtaatatc
     6001 ttctgaccaa cctggcaact cttcatagat aggcttgcaa cgtttcaatt gctcaagact
     6061 agctggatag tagtcaatac gttgaccgtc aagatcatag gccacacaaa ttttcacagt
     6121 atccaagccg ctcaaaacat caatagagtt caaagaaagg ttagtaatac cagaaacacg
     6181 acggctatga cgcatcacaa ctgagtcaaa ccaacctaca cgacgtggac gaccagttgt
     6241 tgtaccatat tcatgaccca cttcacggat acgttctccc acttcatcaa acaactcagt
     6301 tgggaaagga ccatctccta cacgactcgt ataagcttta catacaccta caaccttgtc
     6361 aatcttgctt ggaccgatac cagaaccaat tgtcacacca ccagctacag ggtttgatga
     6421 cgtaacaaat ggataagtac cttgatcgat atctagcata acaccttgtg caccttcaaa
     6481 aagcacacgt ttgccattat caagcgcatc attcaagata acagatgtat ctatcacgta
     6541 tttcttgatt tgttgaccat attcgtaata ttcttcaaaa atatcatcga aaacaatcgc
     6601 tttactgtca tacaattttt caaaaagacg attcttttca gcaaggttac gttctaaacg
     6661 ctcacggaaa atatctttat ctaaaagatc tgcaatacga attccaacac gagcagcctt
     6721 gtccatataa gctggaccaa ttcccttaat tgtcgtacca atcttattgt cgcccttagc
     6781 ttcttcttgc aagcgatcca actcgatatg ataaggcaaa ataacatgcg cacgatcaga
     6841 aatacgcaag ttatcagttg ttacaccttc ctcatgaaga tagctcaact cttttacaag
     6901 agatttagga tttacaacca taccattccc aatgacagat attttttcag ggaagaaaat
     6961 cccagatgga atcaagtgca acttaaattt cttaccgtca atcacaatcg tgtgaccagc
     7021 attatcacca ccttggtaac gtgcaattac ttctgcattc gctgaaagga agtctgtaat
     7081 cttcccttta ccttcatcac cccattgggt acctacaaca acaactgaag tcataatttt
     7141 gtctgagccc tcaggctctt cctttctcac atacatggca ggactctcac ctgcaattat
     7201 atcttacaat ttattataat aaaaaatcgc ctttttatca agaagaaaca atagaaagat
     7261 ttgctatttc caactattaa aaaatgattt agaaaaatta ctagctattt actattatct
     7321 ttccataaaa gagtaaatta gttcggaaat ttactaaaat tacctcaaca agaaataaaa
     7381 ccccgattca ttaccaattt ttcaagatac aaacgataag caacacgata atggtaaacg
     7441 ataaaatccc tacgacaacc aatgccatat ctcactaaat aataaattaa aaatttaaaa
     7501 tgaacatgtt cccagtcaaa attatcacca aatgtaggac catactcttc ttcaatacta
     7561 tcatagaaat tagtcatctg ctcataaatt ttttgtaaca taatcaaata ctccttttct
     7621 tttttataaa cttattctaa caaaaaattt tacacattca ctatcaattc ctgaattgtt
     7681 aaaataccag cctcaacaag ataaaaatag gaaaagttga caaaatagaa acaaatttgc
     7741 tacctaaatt tcaaacgatt aaagttctaa aaagaccgcc ttaaaacttt tgggtaaatc
     7801 ctattagaac tataatattt atatatatgt attatggttc tgattttcta gtataaaaaa
     7861 attcaaacta gaattcttct tagaaaaggc cgttttaagt gctatcattg ctcaaaaatg
     7921 gaggtcgctg agacttctat cgtcaagaag aatcatcaaa ttccttgtat catcaaccaa
     7981 aagattgctc agaagttaat tgaaaagact tctatgaccg acattgatca tcagttgtct
     8041 atttcaactt caactgtcat tcgcaagatc aataattttc actttgagca tgatttttcg
     8101 cgtcttcctg agattatgtc ctaggacgtt gaaacagtcc ggggagtgac tgtttcaatc
     8161 gggagatgga gatgagcttt attgctcagg actttgataa actcaatatc ataactgttc
     8221 ttgagagcag aacacaagcc atcatccgaa atcccatgaa tacaaggcta tcaagcgcta
     8281 ctggaagctc attcaacaag atagtcagaa actgagtgat aaacgatttt atcgccctac
     8341 ttttcgtatg cacttgacta ataaagaaat tctagataaa cttttgagct attccgaaga
     8401 cttgaaacac cactataatc tctatcagct cttgcttttc cacctctgtt tcagactttg
     8461 tttaaaacct tcctcaaaga taaagagaaa atcgtcaacg cccttcaatt accttattcc
     8521 aacgccaaac tggaagccac caataatctc atcaaactta tcaagcacaa tgcctttggt
     8581 tttaggaact ttgaaaactt caaaaaagaa aggacgaaat ttgtcctttc tagatcttcg
     8641 ctttcttcaa cccactacag ttgacaaaga accgaaaaat gtctcgcctc taatatagtc
     8701 aattgaaaca agaacaagag aaaagagcct cgtaaaaggt attgcaactt ggtaatacct
     8761 ttttgaggtt ctttttgata taagcccatg ttttctcaat aggattgtac tcaggtgagt
     8821 agggaggaag aggtaaaagt ttatgcccaa actcctcgca taaaagttct aacttaccca
     8881 ttctatggaa tcttgcatta tccataataa taaccgatgg tgtggttaat gttggtaaga
     8941 gaaacttctg aaaccaagct tcaaaaaagt cgctcgtcac catctcttcg taagtcattg
     9001 gagcgattaa ctcaccattt gttagacctg caaccaaaga aatcctctga tatcttcttc
     9061 cagatacttt acctctt
//
LOCUS       DAVBIC010000068         8676 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.068, whole genome shotgun sequence.
ACCESSION   DAVBIC010000068 DAVBIC010000000
VERSION     DAVBIC010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8676)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8676)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8676
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.068"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            264..1322
                     /locus_tag="VQ664_001933"
     CDS             264..1322
                     /locus_tag="VQ664_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2790037.1"
                     /translation="MKDDQKYLLAGLYSLLVAIFYFPLIESKGIFVSILMAVLLLYLI
                     YFIATVIHIVIIKFIRKKSFKYLVLYPFTYDGSWRFQPINLLYFPEMVRDVIPINLVQ
                     EYCQGQPYGLLKKMLKRIRLSREIALLLATIIVYFFTHRILPLSVFTFIFSYILLFAQ
                     SYLGGNTVWIGNRRLIIDDEFEKILLSKSYIKEISSARYSEYLTCEYKNLTPIILLAI
                     FENLLDSYLLQNQSEVDLDIFYKVLPLLYKEKYTMGFNYFVSLNYLLYKVGFLGIIYD
                     NEALGDLSKQYLNRNISELQDGSFDGGIQDAVASKQIVVINEFIACLNSRCMPSQYDR
                     FFYKDRPYIFSRKSPIKG"
     gene            1637..2611
                     /locus_tag="VQ664_001934"
     CDS             1637..2611
                     /locus_tag="VQ664_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2790038.1"
                     /translation="MKNKRYFFDTILMILLLISTIFCVSPVFIKLDILGTPSHAILTF
                     VLAIPLFYILSQCLHTLLLLVSSIFCKLRPIYFYFIFVIIIGARKYYRILFHQLMGFS
                     PGIAVFYKESQTTKNLFKFYYFLYFTTLISYYFFFTFVYDKPLLLPLIPFSIIIALVQ
                     KLYRIENQQLFLLKSKVLTILESKKNCEFNLQDYHEIWKLQSKSELPCVALSYISLIK
                     PYLSESVREQIDLLEVKRFKKINHPISLYGMLDVIKLNLYLRHYNEKNKYESMLKKIL
                     EVRPDFVLIEQNIDDSLNSSQPLSLSLAISEIQLLLEVYMGIKHVSTK"
     gene            2991..3365
                     /locus_tag="VQ664_001935"
     CDS             2991..3365
                     /locus_tag="VQ664_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0224 family bacteriocin-like peptide"
                     /protein_id="HET2790039.1"
                     /translation="MELVLPNNYVVLEQEEMMYLDGGFSIPRWPVATAINIAFNGVLG
                     GGAISLVRNYIRNYGLRRVTSAIAGAAARYVGVRVANRVAGFALSAINGFAAWMSIGD
                     AITTIWANNDVNRRDPNLNALW"
     gene            3573..4475
                     /locus_tag="VQ664_001936"
     CDS             3573..4475
                     /locus_tag="VQ664_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2790040.1"
                     /translation="MIRKLIVFLLMLPLFVLWLELHVLVNNLLLNLESPLDFVISMSL
                     AFCSLILSKIVLDILYALKDLYKKEGLIKIFPFIFIRRKKVNVRFSPYFSFHRKSLSP
                     DDLRSRIIWSFILEIAIILVFILKIPFAIIMLTTIFFWTIMDINHLVFNKTEFLFNQN
                     KWQKEDSFESNLHKILMDKIQKSELSYSDLMSLLLYDAMNQSTFLTDSELFEDILKKI
                     EDSHNTLLCTGLVELLLYEISISNNNNWQEKVDKIRIQLIRINQLDFFYYTSWLRQNF
                     DFCMNREYHKMKSRKLLLSNKKIV"
     gene            4531..4770
                     /locus_tag="VQ664_001937"
     CDS             4531..4770
                     /locus_tag="VQ664_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HET2790041.1"
                     /translation="MELVLPNNYVVIDEEVMMYLDGGAYLSKRACQGICAAAGVLATA
                     AGKIAYCIGYGVLNRGCDINENPYPWDGFISATVR"
     gene            4767..5495
                     /locus_tag="VQ664_001938"
     CDS             4767..5495
                     /locus_tag="VQ664_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2790042.1"
                     /translation="MSNVDKIRKIHIIVCWVYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLVINSILLMSFPILINKFFPESFLTYTVLISVFILELAIFHL
                     IRKDFDIKLTNEYKKISQFRSKVSQSPWIKYLEISSFILTIFPSILYGKVDNHVLTLI
                     FLIKICVDTTIKFLFIRLFDTSTLMKRRIFFLFALDVIAYLFLGYLLVIQKAGYLFSV
                     LLLFSNFSVPFIKEKEYELFKNSK"
     gene            6630..6869
                     /locus_tag="VQ664_001939"
     CDS             6630..6869
                     /locus_tag="VQ664_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2790043.1"
                     /translation="MKLLDCILDYQERFNGKTCQVSTNYKYLEIFKVNFCLTDLHHLF
                     DLYKITRDYASQTKPAIQDGVFILEDFRNILCTMM"
     gene            7419..>8676
                     /locus_tag="VQ664_001940"
     CDS             7419..>8676
                     /locus_tag="VQ664_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein"
                     /protein_id="HET2790044.1"
                     /translation="MNKKKMILTSLASVAILGAGFVTSQPTFVRAEEAPVASQSKAEK
                     DYDAAVKKYEAAKKEYEDGKAAQKKYEDDQKKTEEKAEEERKASEEEQAANLKYQQEL
                     VKYIRENDPTKKAEAKKAMDEAEKEYKKKQTEFAEVRAKVIPSAEELKKTRQKAEEAK
                     AKEAELTKKVEEAEKKVTEAKQKVDAEHAEEVAPQAKIAELEHEVQKLEKALKEIDES
                     DSEDYVKEGLRAPLQFELDVKQAKLSKLEELSDKIDELDAEIAKLEKDVEDFKNSDGE
                     QAGQYLAAAEEDLVAKKAELEKTEADLKKAVNEPEKPAEETPAPAPKPEQPAEQPKPA
                     PAPQPEKPAEEPENPAPAPQPEKSADQQAEEDYARRSEEEYNRLTQQQPPKAEKPAPA
                     PQPGWKQENGMWYFYNTDGSMATGWLQ"
BASE COUNT         3004 a         1177 c         1582 g         2913 t
ORIGIN      
        1 taaatctaat aaattctatt attatagctc ttggtatgat attggcatta attttggtat
       61 tatcaagagt gtatagaaaa tatttttata gagacgatga tgactaaagt ttttatcaat
      121 aatttgggct ccttgtcaac tgtagtggat tgaagaaaag ctaacgtctg gggaagggtt
      181 taaagctttg ctttatcaaa tattgactta cagagttgct ctattgtatt gatgtattct
      241 tagtaaataa tatggtgttt tgaatgaaag atgatcagaa atatttatta gcgggacttt
      301 attcgcttct agttgcaata ttttattttc cattgattga gtccaagggg atttttgtaa
      361 gtatattgat ggcggtttta cttttatatt taatatactt cattgcaaca gtcattcata
      421 ttgtgataat taagtttata agaaaaaaat cttttaagta tttggttcta tatccattta
      481 cttatgatgg gagctggaga tttcaaccta taaacttact ctactttcca gaaatggtga
      541 gagatgtcat tccgattaat ttagttcaag aatattgcca aggacaacct tacggactgt
      601 taaaaaagat gctgaaaaga attcgattgt cacgagagat agctttactc ctggctacca
      661 ttatcgtcta tttttttacg catagaattc tacctctttc agtatttacg ttcatatttt
      721 cttacatatt gctatttgca caatcttatt tgggtggtaa taccgtttgg attggaaata
      781 gaagattaat aatagatgat gaatttgaaa aaatcttgct ttcaaaaagt tatataaaag
      841 aaatatcatc tgcacgatac tcggaatact tgacatgtga atacaaaaac cttacaccaa
      901 tcatattgtt agctattttt gaaaatttgc ttgactccta cttgcttcag aatcagagtg
      961 aggttgactt agatattttt tataaagttt tacctttgct ttataaagaa aaatatacta
     1021 tgggattcaa ttactttgta agtttaaatt atttactata taaggttgga tttttgggaa
     1081 tcatttacga taatgaagca ttaggagatt tgtcaaaaca atatttaaac agaaatattt
     1141 cggaattaca agatggttct ttcgatggcg gtatacaaga tgctgttgcc tctaaacaaa
     1201 tagtagttat aaatgaattt atagcttgtt taaattccag atgcatgcca tcccaatatg
     1261 atagattttt ttataaagat agaccttata ttttttccag aaagagtcct attaaggggt
     1321 gaaaatttgt tacatttgga ttaacaagtg tcctagggat tagaaataac tctagtatag
     1381 ctagatattt ttgagtaact agaaatatca ttaggctacc catatgattg ccagaaaaga
     1441 tggctgatga atcttattta tactgttgca gtaggcattg tctaggataa ataagctatc
     1501 ttgatggggg aaattggaat aattttagta gaaacattaa aggattatgg acaagtagcg
     1561 caggattagg tgatgcaatg tgctaagttg gcttggtgtt agcagtagta ttatttaaca
     1621 atggaaagta gactaaatga aaaataagcg ttattttttt gacacaattt taatgatttt
     1681 actgcttata agcacgatat tttgtgtcag cccagtattt ataaaattgg acatcttagg
     1741 aaccccctct catgccatct taacctttgt attggcgata ccgttattct atattttgtc
     1801 tcaatgctta catactttgc tattactagt ttcctcaatc ttttgtaaat taagaccaat
     1861 ttatttttat tttatatttg tgatcattat aggagctagg aaatactatc gaattctctt
     1921 tcaccaacta atgggattta gtccaggaat agcagtgttt tataaggaga gtcaaacaac
     1981 taagaatctg tttaaatttt actacttctt gtactttaca acactaattt catactattt
     2041 tttctttact tttgtgtatg acaaaccgtt gcttttgcct cttattccat tttctattat
     2101 catagcatta gtacaaaaac tttatagaat tgagaatcaa caattatttc tgttaaaatc
     2161 aaaggtacta acaatactgg aatctaagaa gaattgtgag tttaatcttc aggattatca
     2221 tgaaatttgg aaattgcaat caaaatctga gttgccatgc gtggctttat cttatatcag
     2281 tttgatcaag ccatatcttt cagagagcgt gcgtgaacaa attgatttat tagaagttaa
     2341 gcgatttaaa aaaataaatc atccaatatc actttatggt atgttggatg ttataaaatt
     2401 aaatctatat ttacggcatt ataatgaaaa aaataaatat gaatcaatgt taaagaaaat
     2461 tttagaggta agaccagact ttgttttaat cgagcagaat attgatgata gtttaaatag
     2521 ctcgcaacca ttatctttat ctttagccat ttcagaaatc caacttttgc ttgaagtgta
     2581 tatggggatc aaacatgttt caaccaagtg ataaaaccag aataatattt gccattatag
     2641 gggcaagttg catattagtc agtatgtatc ttattccact tattaaaact gagaataaat
     2701 tttgggaaat acttttattt atattaggtg tattgctaat tggaattgcg ttactaagtc
     2761 aaaaaaaata aattttgaaa tagtattagt gagttcgcaa tcatttattg ctagtggttt
     2821 agaactgtta agtttcaaac aataattgat tttaaacctt aggtaaccta taaaaacaaa
     2881 taaggtagag aaaggatatc ttatctaggt agctaagtga taaaaacaca gtcgtctatc
     2941 acttgttagg aaactatcct aactatgctt aataaaaaag gagaaaataa atggaactcg
     3001 tattaccaaa taattatgtt gttcttgagc aagaagagat gatgtatctt gatgggggat
     3061 tttctattcc gagatggcct gttgcaacag ccattaatat agcttttaat ggtgttttag
     3121 gtggaggagc aatcagtcta gttagaaatt atattcgtaa ttatggtttg cggcgagtta
     3181 caagcgcaat tgctggagca gctgcaagat atgttggggt acgagttgca aatagagtgg
     3241 caggatttgc actgtctgct attaatggat ttgcagcttg gatgtcaatt ggcgatgcta
     3301 ttacaacaat ctgggccaac aatgatgtaa ataggagaga cccaaattta aacgccttgt
     3361 ggtaactaga tatgggtatt aaaatggaaa aaatttttgt tattattttt tttgtatgtc
     3421 tatttatatc atccataact tttttagcct atgattttgt tagcgaagaa ataaaaaagt
     3481 tgattatttg gattaatgtc gtttttttga ttttaatcat agcaatgatg atttatccaa
     3541 aattaagaaa atgataagga cactgtaaaa ttatgatacg taaactaatt gttttcttac
     3601 taatgctccc tctttttgtc ttgtggctag agttgcatgt cctagtgaat aacttactat
     3661 tgaatctaga atctcccctt gattttgtga ttagtatgag tcttgctttc tgtagtttga
     3721 ttttatcaaa aatagtttta gacatactat acgcattgaa agatttatac aagaaagaag
     3781 gtcttattaa gatttttccc tttattttta taagaaggaa aaaagtgaat gtgagattct
     3841 cgccctattt ttcattccat cgtaaaagtt tgtcgcctga tgatttaaga tctaggatta
     3901 tatggagttt tattcttgaa attgctatta tcctagtatt tattttaaaa attccttttg
     3961 caatcatcat gcttactaca atatttttct ggactataat ggatatcaat catctcgttt
     4021 ttaataagac ggaatttctt tttaatcaaa acaaatggca aaaagaagat tcatttgaaa
     4081 gtaatttgca taagatattg atggacaaaa tacaaaaatc agaattaagc tattctgact
     4141 taatgtccct tcttctctat gatgcgatga accaatccac ctttttaacg gatagtgaac
     4201 tttttgagga tattttgaaa aaaatcgaag attctcataa cacccttctg tgtacaggtc
     4261 ttgtcgagtt actgctgtat gagatttcta ttagtaacaa taacaactgg caagaaaagg
     4321 ttgataaaat tagaatacag ctcatcagaa tcaatcaatt agattttttc tattatacaa
     4381 gttggttaag gcaaaatttt gatttctgta tgaatagaga gtatcataaa atgaaatctc
     4441 ggaaattatt actgagtaat aaaaagatag tttaagttcg tcctatttgt aaaacaaatg
     4501 aaacaatttc aactaaggag gagaaaacaa atggaacttg tattaccaaa taattatgtt
     4561 gtgattgatg aagaagtaat gatgtatctt gatgggggag cttatttaag caagcgtgct
     4621 tgtcaaggaa tttgcgcagc agcaggtgta ttggctacag cagcagggaa aatagcttac
     4681 tgtattggat atggtgttct taatagaggt tgtgatatta acgagaaccc ttatccttgg
     4741 gatggattca tatctgcaac agtaagatga gtaatgtaga taagattcga aaaatacaca
     4801 tcatcgtgtg ttgggtgtat atatttttat cattcagggc gattataaat gatacggagt
     4861 attttttgct tattttttta gcttttatct actcaatagt atcactacct ctatattctg
     4921 tgaaaaataa aatagtatct atctgtctag ttataaattc gattctgtta atgagtttcc
     4981 ccattttaat caataagttt ttcccagaaa gttttttgac ttataccgta ttaataagtg
     5041 tttttatcct agagttagca atctttcatt taattaggaa agattttgat attaaattga
     5101 ctaacgaata taagaaaatt agtcagttta gaagcaaggt gtctcaatct ccttggataa
     5161 aatatttaga gatttctagt tttatattaa ctatatttcc atctattctt tatggtaaag
     5221 ttgataatca tgtactgact cttatctttt tgataaaaat ttgtgtagat actacgataa
     5281 aatttttatt catcagatta tttgacacaa gtactttaat gaagaggaga atattttttc
     5341 ttttcgcatt ggatgttata gcttacttat ttttaggata tcttttagtg attcaaaaag
     5401 caggctattt gttttcggtt ttacttcttt tttctaattt ttcagttcca tttatcaaag
     5461 aaaaggaata cgaattattt aaaaatagca agtaatagaa atatggatta aatcttagaa
     5521 cggcttaaaa tcagatatga taaagggaaa tagtcttatc taggtaacta agtgctacaa
     5581 acacaatcga ggatcacttg ttaggattac attttaatca tgcttaataa gaatggagaa
     5641 ttcctatggg gattgtatta ctctgaagtt tcgaatacct tagttctcgt gattttgagc
     5701 tattctagct ttagaatcct tcagaacgta aaattttaag cagtcaaaga cttagaatag
     5761 cctgaaaaca tttattttat agcaattcta ggcttagaat tgctcatata tatgtatttg
     5821 agctgctcga tagttaggac agctctattc tgagaaatct gagctatcaa tgcttcagaa
     5881 tagtatttcg ccaatggttt ttattgaaga ggtgattgtg ttatgatagt ctaaaataaa
     5941 attgatttaa tagagtaaat ggagaatcgt tacatgaaac atttttttgc aggaattggt
     6001 gagataaaac ttgttggcta cttattgtat atatgtgtag gactagcccc tctttttcat
     6061 atatatgtca taggttcgga actgagtttt gtgaaaatag tgttatctat tttgggagtt
     6121 atatttgtaa gtatgttaac tattgctcga atttatcgga cttttctata aagaatagtt
     6181 tggacttaaa ctgtatctaa aaacagaggt tggtcgatta tcagcctctt tcttgtcgtt
     6241 gaaaagagtg agatatattg acttttgaaa aaaagatgtc ataattgagt tgggataaac
     6301 ctaaaagtaa tatagtagat tgaatctgga atagtccgtt atgactgtta aaatatttct
     6361 agaaattaat ttgactttcc taatcgattt gttcacatct tgtttcaatc tactatactt
     6421 tctcgttaaa ccgttcggca attcatggtg acatggacac atagtagtaa gcacactatg
     6481 tggcttggca gagctaaaaa ctgttccctt gcgataagcc taataagcac aacataggga
     6541 gttagagaag ccgactctaa tcaaccactt tgggcaatag tgagaactgc cccgtgcttt
     6601 tttattttga gaaaatatgg agtttgtcgt tgaaattact tgattgtatt ttggactatc
     6661 aagaaagatt caatggaaaa acatgtcaag tatcaacgaa ttataagtat ttagagattt
     6721 tcaaagtgaa tttttgtttg actgatttac atcatttatt tgacttatac aaaatcacac
     6781 gagattatgc tagtcaaaca aaacctgcta ttcaagatgg tgtttttatt ttagaagatt
     6841 ttagaaatat cctatgtaca atgatgtaat cgaaaggata tctttatgtg agtttatcgg
     6901 cgatatcttc tatatctaag ctagcaagtt gttgcatcgt agctaaggat ttatctaaaa
     6961 atactatgaa attggacgtc atattttttg aggataaaaa taaaagatcc gcagttttag
     7021 gtttacgaag agacaaaagc ggagtattta aaccagttac tctacatttt acaagcgcta
     7081 agaaatatgc taaagttcgt aaaacagatg tgaaagaaat gaaatggcta taaagattgt
     7141 ccgcaggctt aagcttgcgt tttttgttgt ttaacgaaat taaaaaacaa gctctctcat
     7201 cggaaatgtt tttataggaa tgaaggaaga tgatgctatg tttaaaaaga gaatcgaaaa
     7261 gggcaaaagt agtgtcttta tctttttgga gtagaagctt atgatataga aatttgtaat
     7321 aaaaatgtaa tataaaacat ttgacaaata tttacggggg gagtatactt aatataagta
     7381 tagtctaaaa atgactatca gaaaagaggt aaatttagat gaataagaaa aaaatgattt
     7441 taacaagtct agccagcgtc gctatcttag gggctggttt tgttacgtct caacctactt
     7501 ttgtaagagc agaagaagct cccgtagcta gtcagtctaa agctgagaaa gactatgatg
     7561 cagcagtgaa aaaatatgaa gctgctaaga aggaatatga ggacggaaaa gctgctcaga
     7621 aaaagtatga agatgatcag aagaaaactg aggagaaagc ggaagaagaa agaaaagctt
     7681 ctgaagaaga acaagctgca aatctgaaat atcaacaaga gttggttaaa tatatacgtg
     7741 aaaatgatcc aacaaaaaaa gctgaagcta agaaagcaat ggatgaggct gagaaagagt
     7801 ataagaaaaa acaaacggaa tttgctgaag ttcgtgcaaa ggtaattcct agcgcggaag
     7861 aattaaaaaa gactagacaa aaagcagaag aggctaaagc aaaagaagca gaacttacta
     7921 aaaaagtaga agaagctgag aaaaaagtta ctgaagccaa acaaaaagtg gatgcagaac
     7981 atgctgaaga agtcgctcct caagctaaaa tcgctgaatt ggaacatgaa gttcagaaac
     8041 tagaaaaagc tctcaaagag attgatgagt ctgattcaga agattatgtt aaagaaggtc
     8101 tccgtgctcc tcttcaattt gaattggatg ttaagcaagc taaactatca aaacttgaag
     8161 agttgagtga taagattgat gagttagacg ctgaaattgc aaaacttgaa aaagatgtag
     8221 aagatttcaa aaactcagac ggtgagcaag ctggacaata ccttgctgca gctgaagaag
     8281 acttagttgc taaaaaagct gaattagaaa aaactgaagc tgaccttaag aaagcagtta
     8341 atgagccaga aaaaccagct gaagaaactc cagctccagc accaaaacca gagcaaccag
     8401 ctgaacaacc aaaaccagcg ccggctcctc aaccagaaaa accagctgaa gagcctgaga
     8461 atccagctcc agcaccacaa ccagagaagt cagcagatca acaagctgaa gaagactatg
     8521 ctcgtagatc agaagaagaa tataatcgct tgacccaaca gcaaccgcca aaagcagaaa
     8581 aaccagctcc tgcaccacaa ccaggttgga aacaagaaaa cggtatgtgg tacttctaca
     8641 atactgatgg ttcaatggct acaggttggc tacaaa
//
LOCUS       DAVBIC010000069         8164 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.069, whole genome shotgun sequence.
ACCESSION   DAVBIC010000069 DAVBIC010000000
VERSION     DAVBIC010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8164)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8164)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8164
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.069"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            226..6657
                     /locus_tag="VQ664_001941"
     CDS             226..6657
                     /locus_tag="VQ664_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HET2790045.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPNEVVLADTSSSEDALNISDKEKV
                     VVDKETENKEKHEDIHNAIETSQDFKEKKTAVIEGKEVVSKNPVTDNNTSNEEARIKE
                     DSNQSQGDHTDSFVNKNTENPKKEDKVVYIAEFKDKESGEKAIKQLSNLKNTKVLYTY
                     DRIFNGSAIETTPDNLDKIKQIEGISSVERAQKVQPMMNHARKEIGVEEAIDYLKSIN
                     APFGKNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKI
                     PHAFNYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQ
                     IFSYKMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRAL
                     RKAGIPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQT
                     VEFDKVNIGGESFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDL
                     RGKIAVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGT
                     KSQVFSISGDDGVKLWNMINPNKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVG
                     DEKEIDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVIN
                     GKSTYGYMSGTSMATPIVAASTVLIRPKLKEMLERPVLKNLKGDDKIDLTSLTKIALQ
                     NTARPMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGS
                     ISLKEIKGDKKYFTIKLHNTSNRPLTFKVSASAITTDSLTDRLKLDETYKDEKSPYGK
                     QIVPEIHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESV
                     EEMEALNSNGKKINFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSRSKTLGGYDDDGK
                     PKIPGTLNKGIGGEHGIDKFNPAGVIQNRKDKNTTSLDQNPELFAFNNQGINAPSSSG
                     SKIANIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQRDLKVIS
                     REHFIRGILNSKSNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATK
                     IRGQFEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLIT
                     KDTYHKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYA
                     GEGQGRNRKLDKDGNTIYEIKGAGDLRGKIIEVIALDGSSNFTKIHRIKFANHADEKG
                     MISYYLVDPDKDASKYEKLGEISEDKLKNAKSPEENTNNNQAKDEDSKPDEKSSVEGE
                     ASLEINKTISTIREFENKDLKKLIKKKFREVDDFTSETGKRIEEYDYKYDDKGNIIAY
                     DDGSALQYETEKLDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNSYKSIEI
                     KATKYDSHSKTMIFDLYANINDIVDGLAFAGDMRLFVKDDNQIKAETKIRMPEKNKET
                     KAEYPYVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKGY
                     ALKVTTYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRVLSETTIYADSRNVEDGRSTQ
                     AVLMSALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDKS
                     NVEAIKEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNWE
                     LRVNESVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMDG
                     NVYLQTGYSDLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKRN
                     NGFDGEIQEQHIYVNGKEYTSFDDIKQITDKTLNIKIVVKDFARNTTVKEFILNKDTG
                     EVSELKPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKKD
                     AGYVINLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDLQ
                     REDHSQKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIVG
                     IFLGLKKKNQD"
     gene            complement(6948..7294)
                     /locus_tag="VQ664_001942"
                     /pseudo
     CDS             complement(6948..7294)
                     /locus_tag="VQ664_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632353.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(7389..7574)
                     /locus_tag="VQ664_001943"
                     /pseudo
     CDS             complement(7389..7574)
                     /locus_tag="VQ664_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            7602..7829
                     /locus_tag="VQ664_001944"
     CDS             7602..7829
                     /locus_tag="VQ664_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001827253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2790046.1"
                     /translation="MRERLLTQPLLHADETSYRVLESHSHLTYYWTFLSGKVENQAIT
                     LYHHDQSRSGSVVQEFLGDYSGYVHCDMLRQ"
     gene            7905..8164
                     /locus_tag="VQ664_001945"
                     /pseudo
     CDS             7905..8164
                     /locus_tag="VQ664_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007897432.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         3095 a         1153 c         1608 g         2308 t
ORIGIN      
        1 taatcttatt ttttaacgtg tgctaaaaaa taaattaatg catgttaatt tttcttgaat
       61 taaatttttt taaatgatat actgttttta tggagagata acaattatat ataaatgtac
      121 tactctattt cctagataat acttagtaaa actttttata acaaaggcta gcaaagttaa
      181 agtttattat ctattggaag ttaaataaat atgtaaggaa ttaaaatgaa aaaaagtaca
      241 gtattgtcat taaccacagc tgcagttatt ttagcagcct atgcccctaa tgaggtagtc
      301 ttagcagaca catctagctc tgaagatgct ttaaacatct ctgataaaga aaaagtagta
      361 gtagataagg aaacagaaaa taaagagaaa catgaagata ttcataatgc tatagaaact
      421 tcacaggatt ttaaagagaa gaaaacagca gtcattgagg gaaaagaagt tgttagtaaa
      481 aatcctgtga cagacaataa cactagcaat gaagaagcaa gaatcaaaga agattccaat
      541 caatcccaag gagatcatac ggactcattt gtgaataaaa acacagaaaa tcccaaaaaa
      601 gaagataaag ttgtctatat tgctgaattt aaagataaag aatctggaga aaaagcaatc
      661 aagcaactat ccaatcttaa gaatacaaaa gttttatata cttatgatag aatttttaac
      721 ggtagtgcca tagaaacaac tccagataac ttggacaaaa ttaaacaaat agaaggtatt
      781 tcatcggttg aaagggcaca aaaagtccaa cccatgatga atcatgccag aaaggaaatt
      841 ggagttgagg aagctattga ttacctaaag tctatcaatg ctccgtttgg gaaaaatttt
      901 gatggtagag gtatggtcat ttcaaatatc gatactggaa cagattatag acataaggct
      961 atgagaatcg atgatgatgc caaagcctca atgagattta aaaaagaaga cttaaaagga
     1021 actgataaaa attattggtt gagtgataaa atccctcatg cgttcaatta ttataatggt
     1081 ggcaaaatca ctgtagaaaa atatgatgat ggaagggatt attttgaccc acatgggatg
     1141 catattgcag ggattcttgc tggaaatgat actgaacaag atatcaaaaa ctttaacggc
     1201 atagatggaa ttgcacctaa tgcacaaatt ttctcttaca aaatgtattc tgacgcagga
     1261 tctgggtttg cgggtgatga aacaatgttt catgctattg aagattctat caaacacaac
     1321 gttgatgttg tttcggtatc atctggtttt acaggaacag gtcttgtagg tgagaaatat
     1381 tggcaagcta ttcgggcatt aagaaaagca ggcattccaa tggttgtcgc tacgggtaac
     1441 tatgcgactt ctgcttcaag ttcttcatgg gatttagtag caaataatca tctgaaaatg
     1501 accgacactg gaaatgtaac acgaactgca gcacatgaag atgcgatagc ggtcgcttct
     1561 gctaaaaatc aaacagttga gtttgataaa gttaacatag gtggagaaag ttttaaatac
     1621 agaaatatag gggccttttt cgataagaat aaaatcacaa caaatgaaga tggaacaaaa
     1681 gctcctagta aattaaaatt tgtatatata ggcaaggggc aagaccaaga tttgataggt
     1741 ttggatctta ggggcaaaat tgcagtaatg gatagaattt atacaaagga tttaaaaaat
     1801 gcttttaaaa aagctatgga taagggtgca cgcgccatta tggttgtaaa tactgtaaat
     1861 tactacaata gagataattg gacagagctt ccagctatgg gatatgaagc ggatgaaggt
     1921 actaaaagtc aagtgttttc aatttcagga gatgatggtg taaagctatg gaacatgatt
     1981 aatcctaata aaaaaactga agtcaaaaga aataataaag aagattttaa agataaattg
     2041 gagcaatact atccaattga tatggaaagt tttaattcca acaaaccgaa tgtaggtgac
     2101 gaaaaagaga ttgactttaa gtttgcacct gacacagaca aagaactcta taaagaagat
     2161 atcatcgttc cagcaggatc tacatcttgg gggccaagaa tagatttact tttaaaaccc
     2221 gatgtttcag cacctggtaa aaatattaaa tccacgctta atgttattaa tggcaaatca
     2281 acttatggct atatgtcagg aactagtatg gcgactccaa tcgtggcagc ttctactgtt
     2341 ttgattagac cgaaattaaa ggaaatgctt gaaagacctg tattgaaaaa tcttaaggga
     2401 gatgacaaaa tagatcttac aagtcttaca aaaattgccc tacaaaatac tgcgcgacct
     2461 atgatggatg caacttcttg gaaagaaaaa agtcaatact ttgcatcacc tagacaacag
     2521 ggagcaggcc taattaatgt ggccaatgct ttgagaaatg aagttgtagc aactttcaaa
     2581 aacacggatt ctaaaggttt ggtaaactca tatggttcca tttctcttaa agaaataaaa
     2641 ggtgataaaa aatactttac aatcaagctt cacaatacat caaacagacc tttgactttt
     2701 aaagtttcag catcagcgat aactacagat tctctaactg acagattaaa acttgatgaa
     2761 acatataaag atgaaaaatc tccatatggt aagcaaattg ttccagaaat tcacccagaa
     2821 aaagtcaaag gagcaaatat cacatttgag catgatactt tcactatagg cgcaaattct
     2881 agctttgatt tgaatgcggt tataaatgtt ggagaggcca aaaacaaaaa taaatttgta
     2941 gaatcattta ttcattttga gtcagtggaa gaaatggaag ctctaaactc caacgggaag
     3001 aaaataaact tccaaccttc tttgtcgatg cctctaatgg gatttgctgg gaattggaac
     3061 cacgaaccaa tccttgataa atgggcttgg gaagaagggt caagatcaaa aacactggga
     3121 ggttatgatg atgatggtaa accgaaaatt ccaggaacct taaataaggg aattggtgga
     3181 gaacatggta tagataaatt taatccagca ggagttatac aaaatagaaa agataaaaat
     3241 acaacatccc tggatcaaaa tccagaatta tttgctttca ataaccaagg gatcaacgct
     3301 ccatcatcaa gtggttctaa gattgctaac atttatcctt tagattcaaa tggaaatcct
     3361 caagatgctc aacttgaaag aggattaaca ccttctccac ttgtattaag aagtgcagaa
     3421 gaaggattga tttcaatagt aaatacaaat aaagagggag aaaatcaaag agacttaaaa
     3481 gtcatttcga gagaacactt tattagagga attttaaatt ctaaaagcaa tgatgcaaag
     3541 ggaatcaaat catctaaact aaaagtttgg ggtgacttga agtgggatgg actcatctat
     3601 aatcctagag gtagagaaga aaatgcacca gaaagtaagg ataatcaaga tcctgctact
     3661 aagataagag gtcaatttga accgattgcg gaaggtcaat atttctataa atttaaatat
     3721 agattaacta aagattaccc atggcaggtt tcctatattc ctgtaaaaat tgataacacc
     3781 gcccctaaga ttgtttcggt tgatttttca aatcctgaaa aaattaagtt gattacaaag
     3841 gatacttatc ataaggtaaa agatcagtat aagaatgaaa cgctatttgc gagagatcaa
     3901 aaagaacatc ctgaaaaatt tgacgagatt gcgaacgaag tttggtatgc tggcgccgct
     3961 cttgttaatg aagatggaga ggttgaaaaa aatcttgaag taacttacgc aggtgagggt
     4021 caaggaagaa atagaaaact tgataaagac ggaaatacca tttatgaaat taaaggtgcg
     4081 ggagatttaa ggggaaaaat cattgaagtc attgcattag atggttctag caatttcaca
     4141 aagattcata gaattaaatt tgctaatcat gctgatgaaa aggggatgat ttcttattac
     4201 ctagtagatc ctgacaaaga tgcttctaaa tatgaaaaac ttggtgaaat ttctgaagat
     4261 aaactcaaaa atgcaaagag cccagaggaa aataccaata ataatcaagc taaggatgaa
     4321 gattcaaaac cagatgaaaa aagttcagtt gagggagaag ctagccttga aataaataaa
     4381 actatttcaa caattagaga gtttgaaaat aaagacctaa agaaactcat taaaaagaaa
     4441 tttagagaag ttgatgattt tacaagtgaa actggtaaga gaatagagga atacgattat
     4501 aaatacgatg ataagggaaa tattattgct tatgacgatg gtagtgcctt acaatatgaa
     4561 actgaaaaac ttgacgaaat aaaatcaaaa atttatggtg ttctaagccc atctaaagat
     4621 ggacactttg aaattcttgg aaagataagc aatgtttcta aaaatgccaa ggtatattat
     4681 ggaaatagct ataaatcgat agaaatcaaa gcgactaagt atgattcaca ttcaaaaacg
     4741 atgatatttg atttatacgc taatattaat gatattgtag atggattagc ttttgctgga
     4801 gatatgagat tatttgttaa agatgacaat caaataaaag ctgaaactaa gattagaatg
     4861 cctgaaaaaa ataaggaaac taaagcagaa tatccctatg tatcaagtta tgggaatgta
     4921 atcgaattag gagaaggaga tctttcaaag aacaaaccag acaatttaac taaaatggaa
     4981 tctggtaaaa tctattctga ttcagaaaaa caacaatatc tgttaaagga taacatcatt
     5041 ctaagaaaag gctatgcact aaaagtgact acctataatc ctggaaaaac ggatatgtta
     5101 gaaggaaatg gagtctatag caaggaagat atagcaaaaa tacaaaaggc caatcctaat
     5161 ctaagagtcc tttcagaaac aacaatttat gctgatagta gaaatgttga agatggaaga
     5221 agtacccaag ctgtattaat gtcggctttg gacggcttta acattataag gtatcaagtg
     5281 tttacattta aaatgaacga taaaggggaa gctatcgata aagacggaaa tcttgtgaca
     5341 gattcttcta aacttgtatt atttggtaag gatgataaag aatacactgg agaggataag
     5401 tccaatgtag aagctataaa agaagatggc tccatgttat ttattgatac caaaccagta
     5461 aacctttcaa tggataagaa ctactttaat ccatctaaat ctaataaaat ttatgtacga
     5521 aatccagaat tttatttaag aggtaagatt tctgataagg gtggttttaa ctgggaattg
     5581 agagttaatg aatcggttgt agataattat ttaatctacg gagatttaca cattgataac
     5641 actagagatt ttaatattaa gctgaatgtt aaagacggtg acatcatgga ctggggaatg
     5701 aaagactata aagcaaacgg atttccagat aaggtaacag atatggatgg aaatgtttat
     5761 cttcaaactg gctatagcga tttgaatgct aaagcagttg gagtccacta tcagttttta
     5821 tatgataatg ttaaacccga agtaaacatt gatcctaagg gaaatactag tatcgaatat
     5881 gctgatggaa aatctgtagt ctttaacatc aatgataaaa gaaataatgg attcgatggt
     5941 gagattcaag aacaacatat ttatgtaaat ggaaaagaat atacatcatt tgatgatatt
     6001 aaacaaataa cagacaagac actaaacatt aagattgttg taaaagattt tgcaagaaat
     6061 acaaccgtaa aagaattcat tttaaataaa gatacgggag aggtaagtga attaaaacct
     6121 catagggtaa ctgtgaccat tcaaaatgga aaagaaatga gttcaacgat agtgtcggaa
     6181 gaagatttta ttttacctgt ttataagggt gaattagaaa aaggatacca atttgatggt
     6241 tgggaaattt ctggtttcga aggtaaaaaa gacgctggct atgttattaa tctatcaaaa
     6301 gataccttta taaaacctgt attcaagaaa atagaggaga aaaaggagga agaaaataaa
     6361 cctacttttg atgtatcgaa aaagaaagat aacccacaag taaaccatag tcaattaaat
     6421 gaaagtcaca gaaaagagga tttacaaaga gaagatcatt cacaaaaatc tgattcaact
     6481 aaggatgtta cagctacagt tcttgataaa aacaatatca gtagtaaatc aactactaac
     6541 aatcctaata agttgccaaa aactggaaca gcaagcggag cccagacact attagctgcc
     6601 ggaataatgt ttatagtagg aatttttctt ggattgaaga aaaaaaatca agattaagac
     6661 aaaagctata gaaaaaaatg gtttatgtac tgagattaga tagtgaggtg atgacatagt
     6721 tttgtgaaaa cagccattta taactcaatt atttagttta cttcactatt gatactattt
     6781 ggagttatta atggacttag tttagataac taatgaattg attgaaaggg ttagtattga
     6841 caatattggt catattgatt agaaaataga gtctatcaaa atttaaaggc taatagaggt
     6901 gatgagacaa tttcggctct ttgtcaactg tagtgggttg aagtcagcta agctcgagaa
     6961 aggacaaatt ttgtcctttc ttttttgata ttcagagcga tgaaaatccg ttttttgaag
     7021 ttttcaaagt ttcgaaaacc aaaggcattg cgcttgataa gtttgatgag attattggtc
     7081 gcttccagtt tggcattaga atagtgtagt tgaagggcat tgacaatctt ctctttatct
     7141 ttgaggaagg ttttagagga tgaacctgat tcagattgtc ctcaatgagt ccgaaaaatt
     7201 tgtcaggctc cttattctga aagtgaaaaa gcaagagttg atagagatta tagtggtgtt
     7261 tcaagtcttc tgaatagctc aaaagtttat ctatagtaga ttgaaactag aatagtacac
     7321 ctctgcttct aaaacattgt tagaaatcga tttgactgtc ctgaatgatt tgtcctgtta
     7381 ttatttcatt ttactataaa tccacgttta cgaatctctt tccacacttg ttcaatgggg
     7441 ttcatctctg gtgtgtatgg aggaataaat gcaaaaccaa tattagtcgg aatctttaag
     7501 gtacttgatt tatgccatat agcattgtcc ataacgagta aaagataatc atctggataa
     7561 gcttgtgaaa gctcctattc ctaaagcccc tttataacct cttgcgagag agactattga
     7621 ctcagccctt acttcatgcg gatgaaactt cttatcgggt tctagagagt catagccatc
     7681 tgacctacta ttggaccttt ttgtctggga aagttgagaa tcaagcaatc acgctgtacc
     7741 atcatgatca gagtcggagt ggttcggtag tacaagaatt cctaggagat tattctggct
     7801 atgttcattg tgatatgttg cggcagtaac ttaggacttt agtcctctag ttctgcctat
     7861 gcgatagcag tccaaggttt aggagcaagg cgacgctaag cttggtaaac tgcgaactgc
     7921 tagaagctta tcgtcaactg gaagaagctg aacttgttgg atgttgggcg catgtgagaa
     7981 ggaaattttt tgaagcgacc cccaagcaag cagataaatc atccttagga gctaaaggtt
     8041 tagcttattg tgatcagtta ttttccttgg aaagagactg ggaggctttg ccagctgatg
     8101 aacgactaca gaaacgtcaa gaacatctcc agcccctaat ggaagacttc tttgcttggt
     8161 gccg
//
LOCUS       DAVBIC010000070         8109 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.070, whole genome shotgun sequence.
ACCESSION   DAVBIC010000070 DAVBIC010000000
VERSION     DAVBIC010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8109)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8109)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8109
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.070"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            120..497
                     /locus_tag="VQ664_001946"
     CDS             120..497
                     /locus_tag="VQ664_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HET2790047.1"
                     /translation="MICQFIRDMLDLPAKNVTILEGSNIHVLPSMPYSAQDFYTSIDV
                     LAELDNGIQVIIEIQVHHQNFFINRLWAYLCSQVNQNLEKIRQREGDTHQSYKQIALV
                     YAIAIVDSNYFSDDLAFHSFIVK"
     gene            732..2123
                     /locus_tag="VQ664_001947"
     CDS             732..2123
                     /locus_tag="VQ664_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HET2790048.1"
                     /translation="MNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKIEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKIDQDQSEQIVKNFSDQDLSAWNFDYKDS
                     QIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKHQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            2237..3079
                     /locus_tag="VQ664_001948"
     CDS             2237..3079
                     /locus_tag="VQ664_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HET2790049.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYRAVLEALKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQEQVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     IAQIALAWSLAEGFLPLPKSVTTSRIQANLDCFGIELSHEERETLKTIAVQSGAPRVD
                     DVDF"
     gene            3352..4113
                     /locus_tag="VQ664_001949"
     CDS             3352..4113
                     /locus_tag="VQ664_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HET2790050.1"
                     /translation="MDNLYLVKDDSQLATFRDFVVRNTEKLKDYQSFLKNELAVCDLP
                     QAVIWSDFNAATQIIRESAVPAYTNNRRMVMAPDLAVWKELYLYQLMDYECSQQTQAI
                     ESHYHSLSENFLLQIVGHELAHWSEHFLDDFDGYDSYIWFEEGMVEYISRKYFLTEEE
                     FQAEKICNQSLVELFQKKYGWHSLNDFGSSTYDKNYASIFYEYWRSFLTVDKLVENLG
                     SVQAVLDSYHLWANTEKTFPLLDWFVQQKLIEKEI"
     gene            4483..5400
                     /gene="glyQ"
                     /locus_tag="VQ664_001950"
     CDS             4483..5400
                     /gene="glyQ"
                     /locus_tag="VQ664_001950"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HET2790051.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATGPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEMLLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRVKLLAEDAE"
     gene            5660..7696
                     /locus_tag="VQ664_001951"
     CDS             5660..7696
                     /locus_tag="VQ664_001951"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HET2790052.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKENRLSFEAI
                     QTFSTPRRLAVRVTGLSDKQSDLTEDFKGPAKKIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEVGQAVEAIVPGVVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGSRVSRGHRFLGKETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKEIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKAGLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEDFKPSVESLSRAFNLAEKAEGVATVDSELFENDQEKALAEAVETLVLSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            7738..7995
                     /locus_tag="VQ664_001952"
     CDS             7738..7995
                     /locus_tag="VQ664_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002901318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HET2790053.1"
                     /translation="MDPKKIARINELAKKKKTEGLTPEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
BASE COUNT         2555 a         1431 c         1794 g         2329 t
ORIGIN      
        1 gctttctttt ccgaataaat agatagaagc atagaatcta gcaaacctag atttaaaaat
       61 gtgctataat agaaggagga aaaggaggat tctcagacat ccaggtatca gcccaactaa
      121 tgatttgtca atttatccgc gatatgctgg acttgccagc aaaaaatgtg acgattttgg
      181 agggaagtaa cattcacgtc ttgccttcca tgccctactc agcgcaagat ttctatacta
      241 gtatagacgt cttggcggag ttagataatg gaatccaagt tatcatcgaa attcaggttc
      301 atcatcagaa ttttttcatc aatcgcctat gggcttatct gtgcagtcag gttaatcaaa
      361 acctagaaaa aattcgccaa cgtgaaggtg atacccacca gagctacaaa caaatcgcac
      421 tagtatacgc tatcgcaatt gtcgatagta attacttctc agatgaccta gcttttcata
      481 gttttatagt aaaatgaaat gagaacagga caaatcgatc aggacagtca aatcgatttc
      541 taacaatgtt ttagaagtat aggtctacta ttctagcttc aatctactag aaattccata
      601 gatagaaaac tacataatct ctacagatac ggatgttgga gttgatgtaa gatgctttgg
      661 cttgctagag gaattgtgga ttgccaaatt gtatcattga aattattgct caaatttgtt
      721 atgatataaa tatgaataaa agtagactag gacgtggcag acacgggaaa acgagacatg
      781 tattattggc tttgattggt attttagcaa tttctatttg cctattaggc ggatttattg
      841 cttttaagat ctaccagcaa aaaagttttg agcaaaagat tgaatcgctc aaaaaagaga
      901 aagatgatca attgagtgag ggaaatcaga aggagcattt tcgtcagggg caagccgaag
      961 tgattgccta ttatcctctc caaggggaga aagtgatttc ctctgttagg gagctgataa
     1021 atcaagatgt taaggacaag ctagaaagta aggacaatct tgttttctac tatacagagc
     1081 aagaagagtc aggtttaaag ggagtcgtta atcgtaatgt gaccaaacaa atctatgatt
     1141 tagttgcttt taagattgaa gagactgaaa agaccagtct aggaaaggtt cacttaacag
     1201 aagatgggca accttttaca cttgaccaac tgttttcaga tgctagtaag gctaaggaac
     1261 agctgataaa agagttgacc tccttcatag aggataaaaa aatagatcaa gaccagagtg
     1321 agcagattgt aaaaaacttc tctgaccaag acttgtctgc atggaatttt gattacaagg
     1381 atagtcagat tatcctttat ccaagtcctg tggttgaaaa tttagaagag atagccttgc
     1441 cagtatctgc tttctttgat gttatccaat cttcgtactt actcgaaaaa gatgcggcct
     1501 tgtaccaatc ttactttgat aagaaacatc aaaaagttgt cgctctaacc tttgatgatg
     1561 gtccaaatcc agcaacgacc ccgcaggtat tagagaccct agctaaatat gatattaaag
     1621 cgactttctt tgtgcttggg aaaaatgttt ctgggaatga ggacttggtg aagaggataa
     1681 aatctgaagg tcatgttgtt ggaaaccata gttggagcca tccgattctc tcgcaactct
     1741 ctcttgatga agctaaaaag cagattactg atactgagga tgtgctaact aaagtgctgg
     1801 gttctagttc taaactcatg cgtccacctt atggtgctat tacagatgat attcgcaata
     1861 gcttggattt gagctttatc atgtgggatg tggatagtct ggactggaag agtaaaaatg
     1921 aagcatctat tttgacagaa attcagcatc aagtagctaa cggctctatc gttttgatgc
     1981 atgatattca cagtccgaca gtcaatgcct tgccaagggt cattgagtat ttgaaaaatc
     2041 aaggttatac ctttgtgacc ataccagaga tgctcaatac tcgcctaaaa gctcatgagc
     2101 tgtactatag tcgtgatgaa taagcaagaa aaaataggtc tgttagatat ttgacagact
     2161 tattttttac agaatatagt actacttaaa aaatgtttta tgctataatt gatgaataaa
     2221 atagaaggag aagcatatga atacctatca attaaataat ggagtagaaa ttccagtatt
     2281 gggatttgga acttttaagg ctaaggatgg agaagaagcc tatcgtgcag tgttagaagc
     2341 cttgaaggct ggttatcgtc atattgatac ggcggcgatt tatcagaatg aagaaagtgt
     2401 tggtcaagca atcaaagata gcggagttcc acgtgaagaa atgttcgtaa ctaccaagct
     2461 ttggaatagt cagcaaacct atgagcaaac tcgtcaagct ttggaaaaat ctatagaaaa
     2521 actgggcttg gattatttgg atttgtattt gattcattgg ccgaacccaa aaccgctcag
     2581 agaaaatgac gcatggaaaa ctcgcaatgc ggaagtttgg agagcgatgg aagacctcta
     2641 tcaagaaggg aaaatccgtg ctatcggcgt tagcaatttt cttccccatc atttggatgc
     2701 cttgcttgaa actgcaacta tcgttcctgc ggtcaatcaa gttcgcttgg cgccaggtgt
     2761 gtatcaagaa caagtcgtag cttactgtcg tgaaaaggga attttattgg aagcttgggg
     2821 gccttttggt cagggagaac tatttgatag caagcaagtg caagaaatcg cagcaaatca
     2881 cggaaaatcg attgctcaga tagccttggc ctggagcttg gcagaaggat ttttaccact
     2941 tccaaaatct gtcacaacct ctcgtattca agctaatctt gattgctttg gaattgaact
     3001 gagtcatgag gagagagaaa ccttaaaaac gattgctgtt caatcgggtg ctccacgagt
     3061 tgatgatgtg gatttctaga aaatcataaa aagaattgta cattattcta atttttgata
     3121 taatagtcag caggaaagaa agtcttatgg cgttcttcaa gcgagcttgg gatagtggga
     3181 gccaagtagg gcaaaataat gagctggcgc tttctgtagt attttcaaaa acaatgaagt
     3241 aataaattag ggtggaaccg cgtttctgac gcccctaggt taaatcaacc taggattgtc
     3301 ggacgcggtt cttttgctta ttcagtctat tgtgtgaaag aaaggagagc cgtggacaac
     3361 ctttatcttg taaaagacga tagtcaacta gctacatttc gtgattttgt agtaagaaat
     3421 actgaaaagt tgaaagatta tcaatctttt ttaaagaatg aacttgcagt ctgtgattta
     3481 ccgcaagccg ttatttggtc agattttaat gctgctacac agattattag ggaaagcgct
     3541 gttccagcct atacaaataa tagacgaatg gttatggcgc ctgatttagc tgtttggaaa
     3601 gagttgtatt tgtatcaatt gatggactac gagtgttctc agcaaactca agcaatagaa
     3661 agtcactatc attctttatc tgaaaatttc ctcttacaga ttgtaggaca tgagttagct
     3721 cattggtcgg agcatttttt agatgatttt gatggttatg actcttatat ctggttcgaa
     3781 gaggggatgg ttgaatatat tagtcgcaag tatttcttga cagaagagga atttcaagcg
     3841 gaaaaaattt gtaatcaatc tctcgtagaa ctttttcaga agaagtatgg ttggcattca
     3901 ttgaatgatt ttggttcttc gacttatgat aagaactatg caagtatttt ttatgaatac
     3961 tggcgcagct ttttgacagt agataagttg gtagaaaatt taggtagtgt acaagcggtc
     4021 ttagattctt atcatttatg ggcaaataca gaaaaaactt ttcccttgtt agattggttt
     4081 gttcagcaga aattaattga aaaagaaata taaaaactaa aggagtaaac aatgtctaag
     4141 aaattgacat ttcactgcgt cagtggcaga aacctcctta cagtcggact gccccacgct
     4201 cagcactaga gtgcctgagc tagacgcagt actaactcgt cttgcctcgt atgatcgacg
     4261 aggcagactc atgtcgcaag taattatttt ttattaagga gtaaacaatg tctaagaaat
     4321 taacatttca ctgcatcagt ggcagaaacc tccttacagt cggactgccc cacgctcagc
     4381 accctagtgc tgagctagac gcagtactaa ctcgtcttgc ctcgtataat cgacgaggca
     4441 gactcgtgtc gcaagaaatc attttttatt aaggagtaaa caatgtctaa gaaattaaca
     4501 tttcaagaaa ttattttgac tttgcaacaa ttttggaatg accaaggttg tatgcttatg
     4561 caggcttatg acaatgaaaa aggtgcgggg acaatgagtc cttacacttt ccttcgtgct
     4621 atcggacctg agccatggaa tgcagcttat gtagagccat cacgtcgtcc tgctgacggt
     4681 cgttatgggg aaaaccctaa ccgtctctac caacaccacc aattccaggt ggtcatgaag
     4741 ccttctccat caaatatcca agaactttac cttgagtctt tggaaaaatt gggaatcaat
     4801 cctttggagc acgatattcg ttttgttgag gacaactggg aaaacccatc aactggttca
     4861 gctggtcttg gttgggaagt ttggcttgac ggaatggaaa tcactcagtt cacttatttc
     4921 caacaagtcg gtggattggc aactggccct gtgactgcgg aagttaccta tggtttggag
     4981 cgcttggctt cttacattca agaagtagac tctgtctatg atatcgagtg ggctgatggt
     5041 gtaaaatacg gagaaatctt tatccagcct gagtatgagc actcaaaata ttcatttgaa
     5101 atttcggacc aagaaatgtt gcttgaaaac tttgataagt ttgaaaaaga agctggtcgt
     5161 gcattagaag aaggcttggt acaccctgcc tatgactatg ttctcaaatg ttcacatacc
     5221 tttaatctgc ttgacgcgcg tggtgccgta tctgtaacag agcgtgcagg ctatatcgct
     5281 cgtatccgta acttggcccg tgttgtagcc aaaacctttg ttgcagaacg caaacgccta
     5341 ggttacccac ttttggatga agaaacacga gttaaacttt tagcagaaga cgcagaatag
     5401 tgagtaatac tgtactctaa aatcgttaga ggcaagtcga agacttgcta gagggatatg
     5461 caccgccgta ctgttatgtg gggatttttg aaaccttagg ttcaaaaatc agtcagctaa
     5521 atccactttg atgagattgt tggaaatctt gataaattta gcattggatt tccatacaga
     5581 ctcacagagt tagttagcga cgtccccagt acctaaggtg catatcaaaa aagattgaag
     5641 aaaatgtaaa ggaaaaaaca tgacaaaaaa cttattagta gaactcggtc ttgaagaatt
     5701 accagcctat gttgtcacac caagtgaaaa acaactaggc gaaaaaatgg cagccttcct
     5761 caaggaaaac cgcctgtctt ttgaagccat tcaaaccttc tcaacaccac gtcgtttggc
     5821 tgttcgtgtg actggtttat cagacaaaca gtctgatttg acagaagatt tcaagggacc
     5881 agcaaagaaa attgccttgg atagtgatgg aaactttacc aaagcagctc aaggatttgt
     5941 ccgtggaaaa ggcttgactg ttgaagatat cgaattccgt gaaatcaagg gtgaagaata
     6001 tgtctatgtc actaaggaag aagttggtca agcagttgaa gccattgttc ctggtgttgt
     6061 agatgtcttg aagtcattga ctttccctgt cagcatgcac tgggctggaa atagctttga
     6121 atacattcgt cctgtccaca ctttaactgt tctcttggat gagcaagagt ttgacttgga
     6181 tttccttgat atcaagggaa gtcgtgtgag ccgtggccat cgtttcttgg ggaaagaaac
     6241 caaaattcag tcagcattga gctatgaaga agaccttcgt aagcagtttg taatcgcaga
     6301 tccatgtgaa cgtgagcaaa tgattgttga ccaaatcaag gaaattgagg caaaacatgg
     6361 tgtacgtatc gaaattgatg cggatttgct gaatgaagtc ttgaatttgg ttgaataccc
     6421 aactgccttc atgggaagtt ttgatgctaa ataccttgaa gttccagaag aagtcttggt
     6481 gacttctatg aaggaacacc agcgttactt tgttgttcgt gatcaagatg gaaaactctt
     6541 gccaaacttc atttctgttc gtaacggaaa cgcagagcgt ttgaaaaatg tcattaaagg
     6601 aaatgaaaaa gtcttggtag cccgcttgga agacggagaa ttcttctggc gtgaagacca
     6661 aaaattggtg atttcagatc ttgttgaaaa attaaacaat gtcaccttcc atgagaagat
     6721 tggttccctt cgtgaacaca tgattcgtac gggtcaaatc actgtacttt tggcagaaaa
     6781 agctggtttg tcagtggatg aaacagttga ccttgctcgt gcagcagcca tttacaagtt
     6841 tgacttattg acaggtatgg ttggtgaatt tgacgaactc caaggaatta tgggtgaaaa
     6901 atacaccctt cttgctggtg aaactccagc ggtggcagct gctattcgtg aacactacat
     6961 gcctacatca gctgaaggag aacttccaga gagcaaggtc ggcgcagttc tagccattgc
     7021 agacaaattg gatacgattt tgagtttctt ctcagtagga ttgattccat caggttctaa
     7081 tgacccttat gcccttcgtc gtgcaactca aggtgtggtt cgtatcttgg atgcctttgg
     7141 ttggcacatt gctatggatg agctgattga tagcctttat gcattgaaat ttgacagttt
     7201 gacttatgaa aataaagcag aggttatgga ctttatcaag gctcgtgttg ataagatgat
     7261 gggctctact ccaaaagata tcaaggaagc agttcttgca ggttcaaact ttgttgtggc
     7321 agatatgttg gaagcagcaa gtgctctcgt agaagtaagc aaggaagaag attttaaacc
     7381 atctgttgaa tcactttctc gtgcctttaa cctggctgag aaggcagaag gggttgctac
     7441 agttgattca gaactatttg agaatgacca agaaaaagct ttggcagaag cagtagaaac
     7501 actcgtttta tcaggacctg caagtcagca attgaaacaa ctctttgcgc ttagcccagt
     7561 cattgatgct ttctttgaaa atactatggt aatggctgaa gatcaggctg tccgtcaaaa
     7621 tcgtttggca atcttgtcac aactaaccaa gaaagcagct aagtttgctt gttttaacca
     7681 aattaacact aaataaaatt tgataaacgg actttatctt attacaaagg agaagaaatg
     7741 gatccgaaaa aaattgctcg tatcaatgag cttgctaaaa agaaaaaaac agaaggctta
     7801 acaccagaag aaaaagtgga acaagccaaa ctacgtgagg agtacatcga aggttatcgc
     7861 cgcgctgttc gtcaccacat tgaaggaatc aaaattgtgg acgaagaagg aaacgatgtt
     7921 acaccagaaa aactacgcca agtacaacgt gaaaaaggat tacatggccg tagtcttgat
     7981 gacccaaatt cataatatgt actctttctt ttaacaaaga tagatgaaac gataacaaag
     8041 agactagcag tttgtgtttg ctagtctttt ttcgctaaaa aaggaaccat aatggttcct
     8101 aaaaactat
//
LOCUS       DAVBIC010000071         7490 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.071, whole genome shotgun sequence.
ACCESSION   DAVBIC010000071 DAVBIC010000000
VERSION     DAVBIC010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7490)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7490)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7490
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.071"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            <1..1039
                     /locus_tag="VQ664_001953"
     CDS             <1..1039
                     /locus_tag="VQ664_001953"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018351.1"
                     /note="Produces ATP from ADP in the presence of a proton
                     gradient across the membrane. Subunit I is part of the
                     membrane proton channel; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HET2790054.1"
                     /translation="IKVMDERFGHSIYIYESETLSDNQDEIPIKLTNHSLIEPFELLT
                     EMYALPKYYEKDPTPVLAPFYFTFFGMMVADLGYGLLLFLGTMLALKIFHLPSETKRF
                     LKFFNILGVAVAIWGGIYGSFFGYELPFHLISTTSDVMIILVVSVVFGFITVFAGLLA
                     SGLQKVRMKKYAEAYNSGFVWCVILLGLLFIAVGMLMPDMRLLFVLGKWVSIFNAVGI
                     LVVSIIQAKSLSGIGAGLFNLYNISSYIGDLVSFTRLMALGLSGASIASAFNLIVGLF
                     PGTLAKLTIGLVLFILLHAINIFLSLLSGYVHGARLIFVEFFGKFYEGGGKPFQPLKA
                     SEKYIKVITKN"
     gene            1055..1531
                     /locus_tag="VQ664_001954"
     CDS             1055..1531
                     /locus_tag="VQ664_001954"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HET2790055.1"
                     /translation="MEHLATYFSTYGGAFFAALGIVLAVGLSGMGSAYGVGKAGQSAA
                     ALLKEQPEKFASALILQLLPGTQGLYGFVIGILIWLQLTPELPLEKGVAYFFVALPIA
                     IVGYFSAKHQGNVAVAGMQILAKRPKEFMKGAILAAMVETYAILAFVVSFILTLRV"
     gene            1565..2146
                     /locus_tag="VQ664_001955"
     CDS             1565..2146
                     /locus_tag="VQ664_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000067169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2790056.1"
                     /translation="MSNLENLRESVIEQAHEKGRMKLLDSKKKIDDEFEMQKSVIVKK
                     KEVEHERKLKELQQKYQIIFQQLKNKERQSTLVSKQKILKELFQSALIEMESWSADKE
                     MEFIYRILERYSQQEVIVTFGERTLAKFNLEQLEKLKFSFPNHLFSEQPISNESGLLI
                     SIGKIDDNYLYKTLIGSISKEESSSIANQIFIN"
     gene            2211..3218
                     /locus_tag="VQ664_001956"
     CDS             2211..3218
                     /locus_tag="VQ664_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HET2790057.1"
                     /translation="MDTNLFSKINTTISVKENDFITEDKFQKIIQSKDTETMAFILEA
                     TPYHLSIDVLENPSQTETSLMTKLVNDYRWAYAESPSNKIVTLFALRYVYHNIKVLLK
                     SKAAIKKDFSKLLIPIGIFDIESLKHLVSSLHSDTLPDFMVHEVESIWNEYETFNNIR
                     VLDVGADLAYFKHLKLLSNELDEVLSQVIVAMIDFYNIITVKRGLSQNKSHGDILQLL
                     SDEGSISAKEFIYIVENQEIFVWFNKINPSLDSIFSTYELKMQDATISSSELEFLCDL
                     LLYKILDQGRYNVDGPLVLARYLLGCEFEVKNLRMIISALQNTIPFGSIKERIRPHYG
                     S"
     gene            3208..3528
                     /locus_tag="VQ664_001957"
     CDS             3208..3528
                     /locus_tag="VQ664_001957"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HET2790058.1"
                     /translation="MEANKYKIGIIGSRDIILPFSMIGFDIFPAYQEQEAINTLRKLA
                     QSDYGVIYITEDIASMILDTIRHYDSQVVPAIILLPTHKQGLNLGLKRIEDNVEKAVG
                     HNIL"
     gene            3591..5366
                     /locus_tag="VQ664_001958"
     CDS             3591..5366
                     /locus_tag="VQ664_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HET2790059.1"
                     /translation="MTQGKIIKVSGPLVIASGMQEANIQDICRVGKLGLIGEIIEMRR
                     DQASIQVYEETSGLGPGEPVVTTGEPLSVELGPGLISQMFDGIQRPLDRFKLATHNDF
                     LVRGVEVPSLDRDIKWHFDSTIAIGQKVSTGDILGTVKETEVVNHKIMVPYGVSGEVV
                     SIASGDFTIDEVVYEIKKLDGSFYKGTLMQKWPVRKARPVSKRLIPEEPLITGQRVID
                     TFFPVTKGGAAAVPGPFGAGKTVVQHQVAKFSNVDIVIYVGCGERGNEMTDVLNEFPE
                     LIDPNTGQSIMQRTVLIANTSNMPVAAREASIYTGITMAEYFRDMGYSVAIMADSTSR
                     WAEALREMSGRLEEMPGDEGYPAYLGSRIAEYYERAGRSQVLGIPEREGTITAIGAVS
                     PPGGDISEPVTQNTLRIVKVFWGLDAPLAQRRHFPAINWLTSYSLYKDSVGIYIDGKE
                     KTDWNSKITRAMNYLQRESSLEEIVRLVGIDSLSDNERLTMEIAKQIREDYLQQNAFD
                     SVDTFTSFAKQEAMLSNILTFADQANHALELGSYFTEIMEGTVAVRDRMARSKYVSED
                     RLDEIKIISNEITHQIHLILETGGL"
     gene            5367..6752
                     /locus_tag="VQ664_001959"
     CDS             5367..6752
                     /locus_tag="VQ664_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000111247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HET2790060.1"
                     /translation="MSVIKEYRTASEVVGPLMIVEQVNNVSYNELVEIQLHNGEIRRG
                     QVLEIHEDKAMVQLFEGSSGINLEKSKIRFAGHALELAVSEDMVGRIFNGMGKPIDGG
                     PDLIPEKYLDIDGQAINPVSRDYPDEFIQTGISSIDHLNTLVRGQKLPVFSGSGLPHN
                     ELAAQIARQATVLNSDENFAVVFAAMGITFEEAEFFMEELRKTGAIDRSVLFMNLAND
                     PAIERIATPRIALTAAEYLAFEKDMHVLVIMTDMTNYCEALREVSAARREVPGRRGYP
                     GYLYTNLSTLYERAGRLVGKKGSVTQIPILTMPEDDITHPIPDLTGYITEGQIILSHE
                     LYNQGYRPPINVLSSLSRLKDKGSGEGKTRGDHAPTMNQLFAAYAQGKKVEELAVVLG
                     ESALSDVDKLYVRFTKRFEEEYINQGFYKNRNIEDTLNLGWELLSILPRTELKRIKDD
                     LLDKYLPLVEV"
     gene            6775..7386
                     /locus_tag="VQ664_001960"
     CDS             6775..7386
                     /locus_tag="VQ664_001960"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000251933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HET2790061.1"
                     /translation="MVRLNVKPTRMELNNLKERLKTAERGHKLLKDKRDELMRRFISL
                     IRENNRLRKEVESYLIDNLKSFAVAKSLKNSLMVEELFSIPSKEIELFIEKENIMSVT
                     VPRMHMNITSQNENSEYSYLSSNSEMDDVFATMNSLIDKLLRLAEVEKTCQLMADEIE
                     KTRRRVNGLEYSIIPNLSETIHYIELKLEEAERANLVRIMKVK"
BASE COUNT         2458 a         1042 c         1525 g         2465 t
ORIGIN      
        1 tataaaagtt atggatgagc gttttggaca ttctatttat atttatgaat cggaaacatt
       61 gtcggataat caagatgaaa tacctatcaa attaacgaat cattctttaa ttgaaccatt
      121 tgaattattg acagaaatgt atgctctgcc caaatattat gagaaagatc ctacacctgt
      181 attagcacca ttttacttta cattttttgg aatgatggtt gctgatttag gctatggttt
      241 actattgttt ttaggaacaa tgttagcatt aaaaattttt catctacctt cagaaactaa
      301 gagattttta aaattcttta atatattagg ggtagccgtt gcaatttggg gtggaatcta
      361 tggctcattt tttggatatg agttgccatt tcatctgata tctacaacct ctgatgtcat
      421 gattatatta gtagtgtcag ttgtgtttgg gtttattaca gtatttgcag gtttgttagc
      481 ttcaggacta caaaaagtaa gaatgaagaa atatgcagaa gcatataatt caggatttgt
      541 gtggtgtgtt attctgcttg gcttgttatt tattgctgtc ggaatgttga tgcctgatat
      601 gagactgtta tttgtattag ggaaatgggt atctattttt aatgctgtgg gaattttggt
      661 tgtttctatt attcaagcca aaagcttgtc aggtattgga gcaggattgt ttaatctata
      721 taacatttca tcttatatag gtgatttagt tagtttcact cgattgatgg cattaggatt
      781 atctggagca agtatagcat cagctttcaa tttaattgtt ggtttgtttc cgggaacatt
      841 ggctaaacta acaattggat tagtattatt cattctttta catgcgatca atatttttct
      901 atcgttacta tcaggatatg ttcatggagc acgtctgata tttgttgaat tttttggtaa
      961 gttttatgag ggtggaggaa aaccatttca acctttgaag gcttctgaga aatatattaa
     1021 ggttattaca aagaattaat ggaggatata tataatggaa catttagcaa cttatttttc
     1081 aacctatgga ggagctttct tcgctgcatt gggaattgta ttggcggttg gattaagtgg
     1141 tatggggtct gcttatggag ttggtaaggc tgggcaatct gccgcagctt tactgaaaga
     1201 acagccagaa aagtttgcct ctgctttgat attgcaatta ctgcccggaa cacaaggatt
     1261 atatggtttt gttattggaa ttttgatttg gttgcaatta actccagaac ttcctttaga
     1321 aaaaggcgtt gcttatttct ttgtagctct tccaattgct attgtaggat acttttcggc
     1381 taagcatcaa ggaaatgtag cagtagcggg aatgcaaatc ttggctaaaa gaccaaaaga
     1441 attcatgaag ggagcaattt tggctgccat ggtagaaacc tatgcaattc ttgcctttgt
     1501 cgtatcattc attttgaccc ttcgtgtata agaaattaat ttgctattca aaggaggtgt
     1561 ctaaatgagc aatttagaaa acttacgaga gtctgttatt gaacaagctc atgaaaaagg
     1621 gcgtatgaaa ttattggatt ccaaaaagaa gattgatgat gaatttgaaa tgcaaaagtc
     1681 ggtcattgta aagaaaaaag aagtggaaca tgaacgaaag ttaaaagaat tacaacagaa
     1741 atatcaaata atttttcaac aattaaaaaa taaggaacgc caatcaacgt tagtatcaaa
     1801 acagaaaata ttaaaagaac tttttcaatc tgctttaata gaaatggaat cttggagtgc
     1861 agataaagaa atggagttca tctatcgaat tctggaacga tattcacaac aagaggtcat
     1921 agtaactttt ggggagcgga ctttagctaa attcaatctg gaacaattag agaaattgaa
     1981 attctctttt ccaaatcatt tatttagtga acagcctatc tcaaatgaat caggcttact
     2041 tatttcaata ggtaaaattg atgataacta tttgtataaa acattaattg gatcgatttc
     2101 taaggaagaa agttcaagta tcgcaaatca aatttttatc aattaaggat gaaattggtt
     2161 aatccttctt agaaatttgg agtattccaa taaaattaga aaggtatttt atggatacta
     2221 atcttttttc aaaaataaat acgacgattt cggtaaaaga aaacgatttt attacagaag
     2281 ataaatttca aaaaattata caatccaaag atacggagac aatggcattt atcttagaag
     2341 caactcccta tcatttatcg attgacgttt tagaaaatcc tagtcagaca gagacttcgc
     2401 taatgacaaa attagtcaat gattatagat gggcctatgc tgaaagtccg tctaataaaa
     2461 ttgtgacttt atttgcttta cgatatgttt atcataatat caaagtttta ttaaaatcta
     2521 aggcggcaat taagaaagat ttttctaaat tattaattcc aatagggatt tttgatatag
     2581 aaagtttaaa acatttagtt tcttccttac attcagatac acttcctgat tttatggttc
     2641 atgaagtaga atcaatttgg aatgagtatg aaacttttaa taatattcgt gtacttgatg
     2701 tcggagctga tctagcatat tttaaacatc tgaaactttt atctaatgag ttagatgagg
     2761 tgctgtctca ggttattgtc gcaatgattg acttttataa tattattact gtaaaacgtg
     2821 gtttatctca aaataagagt catggggata ttttacaatt actttcagat gaaggaagta
     2881 tttctgctaa agaatttata tacattgtag aaaatcaaga aatatttgtg tggttcaata
     2941 aaataaatcc aagcttagat tcaatctttt caacttatga attgaagatg caggacgcaa
     3001 caatttcatc ttctgagtta gaatttttat gtgatttatt attgtataaa attttagatc
     3061 aaggaaggta caatgtagat gggccgttag tacttgctag atatttattg ggatgtgagt
     3121 ttgaagtaaa gaatctcaga atgattatat cagctcttca aaatacaatt ccctttggat
     3181 caataaaaga aaggatacgc ccgcattatg gaagctaata agtataaaat tggcataatt
     3241 ggtagccgtg atattatttt accctttagc atgattgggt ttgatatatt tcctgcctat
     3301 caagaacaag aagctataaa tactctaaga aaattagccc aatctgatta tggtgtcatt
     3361 tatatcactg aagacattgc ttcaatgata ttagatacaa ttcgccatta tgattctcaa
     3421 gttgtgcctg ctattatttt attaccgact cataaacaag gtttaaattt aggattaaaa
     3481 cgtatagagg ataatgtgga gaaagcagta ggacacaata ttttataata atgtacaaaa
     3541 ttgtctgtaa tattattcta taatttttgg acttagtaag gagaataact ttgactcaag
     3601 ggaagattat aaaagtatcg ggacctctag ttattgcatc aggtatgcag gaggctaata
     3661 ttcaagatat ttgccgtgta ggtaagctag ggttaatcgg tgaaattatt gaaatgagaa
     3721 gagatcaggc atctatccaa gtctatgagg aaacatctgg tcttggtccg ggagaacctg
     3781 ttgttacaac tggagaacct ctctcggttg aattaggacc aggattgatt tctcaaatgt
     3841 ttgatggcat acaacgccca ttagatcgat ttaaattggc tactcataat gattttctag
     3901 ttcgtggggt agaagttcca agtttggata gagatattaa gtggcatttt gattccacta
     3961 tagcaattgg tcaaaaagtg agtacgggtg atattctagg aactgtcaag gaaaccgagg
     4021 tagttaatca taaaattatg gttccttatg gagtatctgg cgaagtcgtt tctatcgcat
     4081 ctggcgattt tacaattgat gaagttgtat atgaaataaa aaaattggac ggtagtttct
     4141 ataaaggaac gcttatgcaa aaatggcctg ttcgcaaggc gcgtcctgtt tctaaacgtt
     4201 taatcccaga agaaccatta atcacaggtc aacgagttat tgatacattc tttccagtaa
     4261 ccaaaggggg agcagcagct gttcctggac cgtttggagc aggaaagaca gttgtacaac
     4321 accaagtagc taaattttcc aatgttgata ttgttattta tgtcggttgt ggagaacgtg
     4381 gaaatgaaat gacggatgta ctgaatgagt ttcctgagtt gattgaccct aataccggac
     4441 aatcaattat gcaacggaca gttctgattg ctaatacttc aaatatgcct gttgctgctc
     4501 gtgaggcttc aatttataca ggaattacca tggctgagta ttttcgtgat atgggctact
     4561 ctgtcgccat tatggctgat tcgacttcac gttgggcaga agcactacgt gaaatgtcag
     4621 gacgtctaga agaaatgcct ggtgatgagg gttatcctgc ttatctggga agtcgtatcg
     4681 ctgaatatta tgaaagagcg ggacgttctc aggttctagg gattccagaa cgtgaaggaa
     4741 ctattactgc tattggagct gtatcgccac ccggtggaga tatttcagaa ccagttactc
     4801 aaaacacttt acggattgtg aaagtttttt gggggcttga tgctccgttg gcacagagac
     4861 gtcattttcc tgcaattaac tggcttacat cttattcact ctataaagac agtgtgggaa
     4921 tttatataga tggtaaagag aagacagatt ggaatagtaa aataactcgt gcgatgaact
     4981 acttacaacg ggaatctagt ttagaggaaa ttgttcgtct tgttggaatt gattctctgt
     5041 ctgataatga acgactaacg atggaaattg ctaaacaaat tcgagaagat tatttgcaac
     5101 agaatgcttt tgattcagta gatacattca cttcgtttgc aaaacaagaa gcaatgctaa
     5161 gtaatatcct aacttttgct gatcaggcaa atcatgcttt agagttaggt tcttacttta
     5221 cagagattat ggaaggtacc gtggcagttc gagaccgtat ggcgcgaagt aaatatgttt
     5281 cagaagatag attagatgaa atcaaaatta tttcaaatga gattacacat caaattcatt
     5341 tgatattaga aacaggaggt ctataaatga gtgttataaa agaatacaga actgctagtg
     5401 aagttgttgg gcctcttatg attgttgaac aagtaaataa tgtgtcttac aatgagttag
     5461 ttgaaattca acttcataat ggagaaattc gtcgtggaca agttttagag attcacgaag
     5521 ataaagcaat ggttcaactt tttgaaggat ctagtggaat aaatttagaa aagtctaaaa
     5581 ttcgttttgc tggtcatgca ctagaattgg ctgtatctga ggatatggtt ggtcgtattt
     5641 ttaatgggat gggaaaacca attgatggtg gaccagattt aattccagag aaatatttag
     5701 atattgatgg tcaagctatt aatcctgtat ctagagatta tccagatgaa tttattcaga
     5761 cagggatctc ctctattgat catttgaata ctcttgtacg tggtcaaaaa ttaccagtat
     5821 tttcaggttc gggcttacct cataatgaat tagcagctca gatagcaaga caagcgactg
     5881 ttttaaattc tgatgaaaat tttgcggttg tatttgcagc aatgggtatt acttttgaag
     5941 aagctgagtt ttttatggaa gaactcagaa aaacaggagc gatcgatcgt tcagtcttat
     6001 ttatgaactt ggcaaatgat cctgcaattg agcgtattgc aactccccgc attgctttaa
     6061 ccgcggcaga gtatctagct tttgaaaaag atatgcacgt tctagttatc atgacggata
     6121 tgactaacta ttgtgaagcg ttacgtgaag tctcggcagc gcgccgtgaa gttccaggta
     6181 gacgaggcta tccgggatat ttatatacaa atttatcaac tctatatgaa agggctggtc
     6241 gcttagttgg taaaaaaggt tcagtgacac agattcctat tttaacaatg ccagaagatg
     6301 acataacaca tccaattcct gatttaactg gatacattac tgaagggcaa attattttgt
     6361 ctcatgagtt gtataatcaa ggttatcgtc caccaatcaa tgttttatct tctctctctc
     6421 gattaaaaga taagggatct ggagaaggta aaactcgtgg agatcatgct ccaactatga
     6481 atcaactgtt tgcagcctat gcccaaggga aaaaggttga agagttagca gtagtattag
     6541 gagaatcggc tttatctgat gtagataaat tgtatgtgag atttacaaag cgttttgaag
     6601 aagagtacat caaccaagga ttttataaaa atcgaaatat agaagatacg ttgaatcttg
     6661 ggtgggaatt actatcaatt cttcctagaa cagagttaaa acgtatcaaa gatgatttgc
     6721 ttgataaata tttacctttg gtagaagttt aatccagaaa tggagtgatt atctatggta
     6781 cgtttgaatg taaaaccaac tcgtatggaa ttgaataact taaaggaacg tttgaaaaca
     6841 gctgaacgtg gacataagtt attaaaggat aaaagagatg aattgatgag gcgatttatt
     6901 tctttgattc gtgagaataa tcgacttcgg aaagaagtag aaagttatct aattgataat
     6961 ctaaaatctt ttgcagttgc taaatcatta aagaactctc taatggtgga ggaattattt
     7021 tcaattccat cgaaagaaat tgaattattt attgagaaag aaaatatcat gagtgtaaca
     7081 gttcctagaa tgcatatgaa tattacttct caaaatgaga acagtgaata cagctattta
     7141 tcttctaata gtgaaatgga tgatgtattt gctacaatga atagtttaat tgataaatta
     7201 ctaagactgg cagaagttga aaaaacgtgt cagttaatgg ctgatgaaat agaaaaaaca
     7261 cgtagacgtg taaatggttt agaatattcg attattccaa acttgtcgga aactattcat
     7321 tatatagaat tgaaactaga ggaggcagaa agagccaatt tagttcgtat tatgaaagtg
     7381 aagtagttcc tttatttaga tttttaatta gatgaacaaa tatcagcttg gataaggcgg
     7441 taagcctttc taagcttttt taggctcttt gtcaactgta gtgggttgaa
//
LOCUS       DAVBIC010000072         7474 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.072, whole genome shotgun sequence.
ACCESSION   DAVBIC010000072 DAVBIC010000000
VERSION     DAVBIC010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7474)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7474)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7474
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.072"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            60..929
                     /locus_tag="VQ664_001961"
     CDS             60..929
                     /locus_tag="VQ664_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HET2790062.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGPISLTNVQLMILAISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            933..1889
                     /locus_tag="VQ664_001962"
     CDS             933..1889
                     /locus_tag="VQ664_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HET2790063.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKLPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            1889..2653
                     /locus_tag="VQ664_001963"
     CDS             1889..2653
                     /locus_tag="VQ664_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2790064.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKAKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            2653..3363
                     /locus_tag="VQ664_001964"
     CDS             2653..3363
                     /locus_tag="VQ664_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2790065.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKIPAQKIVAGGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            3828..4484
                     /locus_tag="VQ664_001965"
     CDS             3828..4484
                     /locus_tag="VQ664_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HET2790066.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQGLHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKIGILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIVSL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDESIDLPALREKFEANGIQVEEIARTSAKVL
                     "
     gene            4592..5687
                     /gene="prfB"
                     /locus_tag="VQ664_001966"
     CDS             join(4592..4663,4665..5687)
                     /gene="prfB"
                     /locus_tag="VQ664_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HET2790067.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQDKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSFEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            5705..6397
                     /gene="ftsE"
                     /locus_tag="VQ664_001967"
     CDS             5705..6397
                     /gene="ftsE"
                     /locus_tag="VQ664_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HET2790068.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDVPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKRRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            6390..7316
                     /locus_tag="VQ664_001968"
     CDS             6390..7316
                     /locus_tag="VQ664_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2790069.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKI"
BASE COUNT         2208 a         1292 c         1682 g         2292 t
ORIGIN      
        1 agaacctatc aaaaagtgag ggaaaaccct cggaattata aatagaaaga gtgaatctta
       61 tgctccaaca actcgtaaat ggtttgattc taggtagtgt ttacgcgctg ttagccctag
      121 gatataccat ggtttacgga attatcaagc tcatcaactt cgcccatggt gatatttata
      181 tgatgggagc ctttatcggt tatttcttga tcaattcttt ccaaatgaat ttctttgtag
      241 cgcttattgt agctatgcta gcgacagcta ttcttggtgt cgtgattgag tttcttgctt
      301 accgaccttt gcgccactct actcgtattg ctgttttgat tacggctatt ggggtttctt
      361 tcctattgga gtatggaatg gtctatctgg ttggtgccaa tacccgtgcc ttccctcaag
      421 cgattcaaac agttcgatat gatttgggac caattagctt aacaaatgtg cagttaatga
      481 ttttggccat ttccttgatt ttgatgattt tgttacaagt cattgtccaa aagactaaga
      541 tggggaaagc catgcgtgca gtatcagtag atagcgacgc ggcgcaattg atggggatca
      601 atgtaaaccg tacgattagc tttaccttcg ctttgggttc tgctcttgcg ggtgcggctg
      661 gtgttctgat tgctctttat tataactctc ttgagccttt gatgggggtt actccaggtc
      721 ttaaatcttt cgttgccgca gtacttggtg gtatcggaat tattcctggt gcggctcttg
      781 gtggctttgt gattggtcta ttggaaacct ttgcgactgc ctttgggatg tcagatttcc
      841 gtgatgccat tgtttatgga atcttgttgt tgatcttgat tgtccgccca gctggtatcc
      901 ttggtaagaa tgtgaaagag aaggtgtaaa cgatgaagga aaatttaaaa gttaatattc
      961 tatggttact ccttttgtta gctggctata gcttgattag tgtactggtt tcagtcggag
     1021 tacttaatct attctatgta cagattttac aacaaattgg aattaatatt attttggctg
     1081 ttggtctcaa cttaatcgtt ggtttttcag gacaattttc acttggtcat gctggtttca
     1141 tggcgattgg tgcctatgca gcagctatta ttggttctaa attaccaacc tacggtgcct
     1201 tctttggagc tatgcttgta ggggctttgc tttcaggagc agttgcctta cttgtcggca
     1261 ttccaacctt gcgcttgaag ggggactatc ttgcggtagc aactctaggt gtttctgaaa
     1321 ttatccgtat ctttatcatc aatggtggaa gtcttacaaa tggtgcggca ggtatcttag
     1381 ggattcctaa ctttacaact tggcaaatgg tttacttctt tgtcgtgatt acaaccattg
     1441 caaccttgaa cttcttgcgt agcccaattg gccgttcaac cctctctgtt cgtgaagatg
     1501 aaatcgctgc tgagtcagtt ggggttaata cgactaaaat taaaatcatc gcttttgtct
     1561 ttggtgccat tactgcaagt attgctgggt cacttcaggc aggatttatc gggtctgttg
     1621 taccgaaaga ttacaccttc attaactcaa tcaacgtttt gattattgtt gtatttggtg
     1681 gactcggttc cattacaggt gcgattgttt cggctattgt tctgggaatt ttgaatatgc
     1741 ttctccaaga tgttgctagt gtgcgtatga ttatttacgc tttagccttg gtattggtaa
     1801 tgattttcag accaggtgga ctccttggaa cgtgggaact gagcctatca cgtttcttta
     1861 aaaaatctaa gaaggaggaa caaaactaat ggcattactt gaagtaaaac agttaaccaa
     1921 acattttggt ggtctaacag ctgttggaga tgtgactctt gaattgaacg aaggggaact
     1981 ggttggatta atcggtccaa acggagctgg gaaaaccacc cttttcaacc ttttgaccgg
     2041 tgtttatgaa ccaagcgagg gaacagtaac cctagatggt caccttttga atgggaaatc
     2101 accttataag attgcctctt tgggacttgg acgtactttc caaaatatcc gtctctttaa
     2161 agatttaaca gttttagata atgttttgat tgcttttgga aaccatcaca aacagcatgt
     2221 ttttactagt ttcttacgct taccagcttt ttacaagagt gaaaaagaat taaaggctaa
     2281 agctttggaa ttgttgaaaa tctttgattt agatggtgat gcagagactc ttgctaaaaa
     2341 tctttcctac ggacaacaac gtcgtttgga aattgttcgt gcccttgcta cggaacctaa
     2401 aattctcttc ttagatgaac cagcagcagg tatgaaccca caggaaacag ccgaattgac
     2461 tgagttaatt cgtcgtatca aagatgaatt taagattaca atcatgttga ttgaacacga
     2521 tatgaatctg gtcatggaag taacagaacg tatctacgta cttgaatatg gccgtttaat
     2581 tgctcaagga actccagacg aaattaagac caataaacgc gttatcgaag cttatctagg
     2641 aggtgaagcc taatgtctat gttaaaagtt gaaaatcttt ctgtgcatta cggtatgatc
     2701 caagcagtcc gtgatgtaag ctttgaagtt aatgaaggag aagttgtttc ccttatcggt
     2761 gccaacggtg caggtaagac aactattctt cgcaccttgt caggtttggt tcgaccaagt
     2821 tcaggaaaga ttgaattttt aggtcaagaa atccaaaaaa taccagctca gaaaatcgtg
     2881 gcaggtggtc tttcacaagt tccagaagga cgccacgtct ttcctggctt gactgttatg
     2941 gaaaatcttg aaatgggagc tttcttaaag aaaaatcgtg aagaaaatca agctaacttg
     3001 aagaaggttt tctcacgctt tcctcgtctt gaagaacgta agaaccaaga tgcagctact
     3061 ctttcaggag gggaacaaca aatgcttgcc atgggacgcg ctcttatgtc aacaccaaaa
     3121 cttcttcttt tagatgaacc atcaatggga cttgccccaa tcttcatcca agagattttt
     3181 gatatcattc aagatattca gaagcaagga acaaccgtcc tcttgattga acaaaatgcc
     3241 aataaagcac ttgcaatctc tgaccgagga tatgtattgg aaacaggaaa aatcgtccta
     3301 tcaggaacag gaaaagaact cgcttcatca gaagaagtca gaaaagcata tctaggtggc
     3361 taaaacaatc cagtggattg ttttagtcgg cagatgaaga ttacgaagta atcatcaata
     3421 tagtccgggg gcccttttta gtcggtagat tgagattgcg aagcaatcat caaatccaga
     3481 ggattgtttt agccggcaga taaagattac gaagtaatca tcaatatagt ccgggggccc
     3541 tttttagtcg gtggatgaag attgcgaagc aatcatcaaa tccagaggat tgttttagcc
     3601 ggtagattga gattgcaaac aaatctgcat ctacattgaa agcttaattt ctaataattg
     3661 aaaaaatcga atgaaaagtt tcttaccttc attcacagag ctcgatttta gagctctttt
     3721 tgctagctta ttcatacttt tctaaatttt gaaaaagaaa tgtaagcgtt tgatagattt
     3781 gcaaaaagat tgtataatag ggataagaat agaaaaggag aagtctcatg gcagttaaag
     3841 attttatgac ccgcaaggta gtttatatta gtccagatac aacagtatct catgcagcag
     3901 atttgatgag agagcaaggt ttgcaccgtc tgcctgttat cgaaaatgat caattggttg
     3961 gtttggtgac tgagggaacc attgcacaag caagtccatc taaagcaaca agtctttcta
     4021 tctatgagat gaattatctt ctgaataaga caaaagtaaa agatgtcatg attcgcgatg
     4081 ttgtcactgt ctcaggctat gctagtctag aagatgcaac ttatctgatg ttgaaaaata
     4141 agattggtat tctccctgtc gtagataacc atcaagtata cggagttatt actgaccgtg
     4201 acgttttcca agcctttctt gaaattgcag gttatggcga agaagggatt cgtgtacgct
     4261 ttgttacaga agatgaagtt ggtgttcttg gaaaaattgt ttctttgatt gtagaagaaa
     4321 atttgaatat ctcccataca gtcaatattc cgcgtaagga tggtaaggtg attatcgaag
     4381 tgcaaatcga tgaatcaatt gatttaccag ccttgagaga aaaatttgaa gcaaatggta
     4441 ttcaagtgga agaaatcgct cgcacttcag caaaagtctt gtaagaaggg aagtccaaag
     4501 gcttcttttt tcatgaaaag gggattagag caaaagatgg aaagaaatga taaaatatgc
     4561 tataatgaaa taatgtaaaa aaggagtatt tatggacatt tcagtaattc gtcagaaaat
     4621 tgacgcaaat cgtgaaaaat tagcttcttt cagggggtct ctttgacctc gaagggctag
     4681 aggaagagat tgccatcttg gaaaacaaga tgacagaacc tgatttttgg aacgataata
     4741 ttgcggccca aaaaacgtcg caagaattga atgaattaaa aaacacttac aataccttcc
     4801 ataagatgga agagttgcag gatgaagtcg aaattttatt ggattttttg gctgaagacg
     4861 agtcagtgca tgatgaactg gtagcgcagt tagccgaact tgataagata atgaccagct
     4921 acgagatgac tctactcttg tcagaacctt atgaccacaa caatgccatc ttggaaatcc
     4981 atccaggttc tggtggtact gaggcgcagg actggggtga tatgttgctt cgtatgtata
     5041 ctcgttatgg taatgctaaa ggctttaaag tggaagtgtt ggattaccaa gcaggtgatg
     5101 aggctggtat taagtcggta actttatcat ttgaagggcc taatgcctat ggtctcctca
     5161 agtcagaaat gggtgttcac cgcttagtgc gaatctcacc atttgactct gccaaacgtc
     5221 gccatacctc tttcacatct gtagaagtga tgccagaatt ggatgatact attgaagtgg
     5281 aaatccgtga agatgatatc aagatggata ccttccgttc aggtggtgcc ggtggacaaa
     5341 acgtcaataa ggtttcaaca ggtgtacgtt taacccacat tccaactgga attgttgtcc
     5401 aatcaacagt ggatcgtacc cagtatggaa atagagatcg tgccatgaag atgttgcagg
     5461 ctaagctcta tcaaatggag caagataaga aggctgcgga ggtagattct ctcaaaggtg
     5521 agaaaaagga gatcacttgg ggaagccaaa tccgttctta tgtcttcacg ccttatacta
     5581 tggtaaaaga tcaccgaact agctttgagg ttgctcaggt agataaggtt atggatgggg
     5641 acctagatgg ttttatagat gcttatctca agtggcgaat tagctaagat agaaaggaac
     5701 tcacatgtca attattgaaa tgagagatgt cgttaaaaaa tacgacaacg gaacgactgc
     5761 tctacgcggt gtttcggtca gcgttcaacc gggggaattt gcttacatcg taggaccttc
     5821 aggagcaggg aagtcaactt ttattcgttc tctgtatcgt gaagtaaaaa tcgataaagg
     5881 aagtctatca gttgctggtt ttaatctggt taagatcaaa aagaaagatg tcccgcttct
     5941 acgtcgtagt gttggggttg tcttccaaga ttataaattg ttaccaaaga aaactgtcta
     6001 tgaaaatatt gcttacgcta tggaagtaat cggggaaaat cgccgtaata tcaaaagacg
     6061 agtgatggaa gttttggact tggttggatt gaagcataag gttcgttctt tcccaaatga
     6121 actctcaggt ggggagcagc agcgaattgc gattgcgcgt gcaattgtaa ataatcccaa
     6181 agtattgata gctgatgagc caacaggaaa tctggatccg gataattcat gggaaattat
     6241 gaatctcttg gaacggatta acctacaagg gacaactatt ttgatggcga ctcataatag
     6301 ccagattgta aataccttgc gccaccgtgt cattgccatt gaaaatggcc gtgtcgttcg
     6361 tgacgaatca aaaggagagt atggatacga tgattagtag attttttcgc catttatttg
     6421 aagccttaaa aagtttgaaa cgaaatggtt ggatgacagt agctgctgtc agttcagtca
     6481 tgattacttt gaccttggtg gcaatatttg catctgttat tttcaataca gcgaaactag
     6541 ctacagatat tgaaaataat gtccgtgtag tagtttatat ccgaaaggat gtggaagata
     6601 atagtcagac aattgaaaaa gaaggtcaaa ctgttacaaa taatgactac cacaaggtat
     6661 atgattcttt gaagaacatg tctacggtta aaagtgttac cttttcaagt aaagaagaac
     6721 aatatgaaaa attaaccgag ataatgggag ataactggaa aatctttgaa ggagatgcca
     6781 atcctctcta tgatgcctat attgtagagg caaacactcc aaatgatgta aaaactatag
     6841 ccgaagatgc taaaaaaatt gaaggtgtct ctgaggttca agatggcggt gccaatacag
     6901 aaagactctt caagttagct tcatttatcc gtgtttgggg actagggatt gctgctttgt
     6961 taatttttat cgcagttttc ttgatttcaa ataccattcg tattaccatt atttcccgca
     7021 gtcgcgaaat tcaaatcatg cgcttggttg gagctaaaaa cagttatatc cgtggaccgt
     7081 tcttgttaga aggagccttt atcggtttat tgggagctat cgcaccatct gttttggtct
     7141 ttattgttta tcaaattgtt taccaatctg tcaacaaatc gttggtaggg caaaatctat
     7201 ccatgattag tccagattta tttagtccgt tgatgattgc cctactattt gtgattgggg
     7261 ttttcattgg ttcattggga tcaggaatat ccatgcgccg attcttgaag atttaggtaa
     7321 aatagctgct tttatgagga gattgtaaaa tctccttttt tgctacaaga gtttttgaaa
     7381 agagatgcgt agaagaaaag agcttccaaa gaagtccccc agagaagact tcttgatggc
     7441 taatttgaac ttgaaatttg gcgcactaga aatt
//
LOCUS       DAVBIC010000073         7220 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.073, whole genome shotgun sequence.
ACCESSION   DAVBIC010000073 DAVBIC010000000
VERSION     DAVBIC010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7220)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7220)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7220
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.073"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            231..645
                     /locus_tag="VQ664_001969"
                     /pseudo
     CDS             231..645
                     /locus_tag="VQ664_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720030.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(684..1127)
                     /locus_tag="VQ664_001970"
     CDS             complement(684..1127)
                     /locus_tag="VQ664_001970"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HET2790070.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKKGNRPAFTGAAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR"
     gene            complement(1157..3379)
                     /locus_tag="VQ664_001971"
     CDS             complement(1157..3379)
                     /locus_tag="VQ664_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HET2790071.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRMIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYSSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            3790..4032
                     /locus_tag="VQ664_001972"
     CDS             3790..4032
                     /locus_tag="VQ664_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2790072.1"
                     /translation="MTRFEEIFEEYKNPQDTFFYPLVYKENTYEKTAISIFALLMLGV
                     CCLFLFSQQSYKKLVQYYANDQNLPSRITYSEYSDK"
     gene            4372..5001
                     /locus_tag="VQ664_001973"
     CDS             4372..5001
                     /locus_tag="VQ664_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HET2790073.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            complement(5124..7016)
                     /gene="pepO"
                     /locus_tag="VQ664_001974"
     CDS             complement(5124..7016)
                     /gene="pepO"
                     /locus_tag="VQ664_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HET2790074.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVAAVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
BASE COUNT         1985 a         1681 c         1378 g         2176 t
ORIGIN      
        1 ttatcatttt atgacaaaca tactatcgtt aaatgctgat ttaatcgaaa ttttgagtta
       61 taaactcctc agtttcgaac tcaaaattag ccgtgcagga taggataccc ttcataaact
      121 tatataacta ctttaatacc ttaaaaagct aataaaataa ggaatatcta agcaatatac
      181 attctaaaat acctgtacgg gagtgtctct aaagaaaagg aggttttagc atgaaaaaaa
      241 tcatcttcat caaaaccatt caactccttg tcattgatgg aatcatgctg gcatttttga
      301 catttaaaag gggggcttac ttgggactgg attttgattt atagtggttg gctcattttc
      361 tttcatcctg tgctattgac ctatctttca aaccaacttt gtgaccactt tagtcaactc
      421 tattcccaga ttagaccgag attctggcgt tttgctttac aaattctcct atgggatagc
      481 ctgatgattc tctccttggt gtctttaagt gatattccac ttttccttca gggaactctc
      541 ctcatcctag gacatctcat cccttcctat cgcatctgcc aaagcctgaa aagagacttc
      601 ccccaagcat atcaagaacc gatttctttt tggagtattt tatgatcgat gagaaagacc
      661 aagccgactg ggcttggtct ttcttatctc tttttagtat ctaggataat ggtaacaggt
      721 ccgttattaa ccagctcaac ctgcatatct gctccaaaga tacctgtctg aacgggcact
      781 tcttgcgcta atttttgatt gaaagcatca tagaagtctg atgccatatc aggtttagct
      841 gcccctgtaa aggctggacg attgcctttc ttagtatccg caaagagggt aaactgagaa
      901 atagagagga tttctccttc aatatctttg acagacaggt tcatcttgcc ttctgcgtct
      961 gaaaaaatcc gcatattgac cagttttctc acagcatagt ccaaatcttc ctcttggtcc
     1021 tctggtccaa caccaaccag caataaaagt ccctgattga tttttccctg aatctggcct
     1081 tctatactca cttgggcttt tttaacccgt tggataatga ttttcataat agcctttcta
     1141 gtaagagcta ggacaactag ccgttggtcc gtttgacaga gtaaacttct ggcacactct
     1201 taattttatc gacaaccgtg gtcagtgtag agaggttggc aataccgaag gacacatgga
     1261 tattagcaaa cttcatatcc ttggttggtt gggcattgac cgttgaaata ttcttggttg
     1321 tatttgaaag aacttgcagt acatcgttca acagtcctgt acggttgaga ccgtagatat
     1381 cgatatgggc catatactcc ttatttgagc tagagtactg gtcttcccat tccacatcaa
     1441 ggagacgttg ctcgtagttt tcttgggcac gcaggttcat acagtccaca cggtgaatag
     1501 ccacaccacg acccttggta atgtagccaa caatatcgtc accaggcacg gggttacaac
     1561 acttagcaat ccgcactagg agaccagaag caccttcaat aaccactccc ccctcatgct
     1621 tgaccttgag agtttcttta ttttcaacct tgacctcgcc acctttgaca agctcctctg
     1681 cctcagcctt ggccttggca cgctcttcct cacggcgttc cttttcagtc agacggttaa
     1741 agacggtaat cgcaccgatt tccccaaaac caatggccgc aaagagggag tcttctgtct
     1801 tgtaactggt cttttgcaga acttgatcca tgtggcgctt gtccataaat ttatttgcca
     1861 catagccatt ttcttggaac tgagccatca gcatctcacg acccttgttg acagacaatt
     1921 ccttatcttg gtttttaaag aactggcgaa tcttattgcg cgccttgcta gtcttgacca
     1981 tattgagcca gtcacggcta ggtccaaagg agttcgggtt ggcgataatt tcaacctgat
     2041 cccctgtctt taacttggtt gtcagtggaa ccatgcggcc attgaccttg gcaccagttg
     2101 ctttttcacc gaccttggta tggatttcgt aggcaaaatc aatcggtcct gaatctttgg
     2161 gaagagaacg gacagctcca tctggggtaa aaacgtaaat ctcctcagcc agatagtttt
     2221 ccttaacaga gtccacaaat tccttagcat catcagcctg gtcttggagc tccatcatct
     2281 ccttgatcca gttcattcca atagctgatt ccttgctgtt aacttgcccc tttatacctt
     2341 tcttataagc ccagtgagcc gcaaccccgt actcagccac ctcgtgcatt tccttggttc
     2401 gaatctggaa ttcaatcggc ccttttggtc cataaacagt cgtatggata gactgataac
     2461 cattagcctt gcggttggca atatagtctt tgaagcgacc tggcatcggt ttccaaaatt
     2521 catgcacgta accaagcatg gcataaacat cactttgggt atctaaaata caacgaatag
     2581 caatcagatc atagatttcc tcaaaccgtt ttctcttgtc ctgcattttg cggaaaattg
     2641 agtaaatatg cttgggacga ccataaatct tccctttcaa gtgacgttct gtcgtatact
     2701 cctctaattt tgtgactacc tcatccacca aggcctcacg ctccctgcgc ttttccttca
     2761 tcatatgggt aatcttgtaa aactccgttg gattgagata acggaaagac aagtcttcta
     2821 attcccattt gacactggaa atccccaaac gatgggcaag cggggcatag atttccatgg
     2881 tttctttgga aatacgctcc tgcttgtctt ttcgaagatg tttcagggtc cgcatattgt
     2941 gcaagcggtc agacagtttg accaaaataa cgcggatgtc ctcagacatg gccatgagca
     3001 tcttgcgatg attttccgct aattgctcct cgatcgattt gtactcgacc ttgccaagct
     3061 tggtaactcc gtcaacaatc atccgcacat caggaccaaa ctctctttcc aaatcgtcca
     3121 aagtcgcatc tgtatcttcc accacatcat gcaagaatcc acaagctact gttacagcat
     3181 ccagctttag cttagctaaa atacctgcca cttggatagg gtgaatgata taaggctcgc
     3241 ctgatttgcg atattgacca ctgtggcatt caacagcata gaccaaggcc ttatggacaa
     3301 aatgaacatc ctcttccgtt aaatattctt tggttaaagc gacaacttct tcgcctgtta
     3361 aattcacttc tttcggcatc tctactctcc aattcttcct accattttat cactttttta
     3421 agaatatgaa aactagattg gaacagaata agaaaaaaat aattcaaaat tgcttgataa
     3481 ttctgaatta ttggcccata atatactacg aagttagatt ttaaacttag gtgatagaag
     3541 gagagataga agaacggaaa ccatattgta acccaaagac tttctgattt ccccaattcc
     3601 attgaagata cgaaagataa acggtggaac tcgtatcaca tacactggta ccttgactgg
     3661 attttggaat taatactcaa tgaaaatcaa agagcaaact aggaaactag ccacaggttg
     3721 ctcaaagcac tgctttgagg ttgtagataa gactgacaaa gtcagtcaca tatatacggc
     3781 aaggcgacgt tgacgcggtt tgaagagatt tttgaagagt ataaaaatcc tcaagatact
     3841 ttcttctatc ctttagttta taaggagaat acctatgaaa aaactgctat ttctatcttt
     3901 gctctcctaa tgttaggagt ttgctgcctg ttcctattca gccagcaaag ctataaaaaa
     3961 ctcgttcaat actatgctaa cgaccagaac ctgcccagta ggataactta tagtgaatat
     4021 agcgacaaat gagaagccaa ctacggtagc actctaaaca tcacgtctat caaacaagct
     4081 aatgacggag tttatgcaac ctatgaaggg caattgacac ctttccaata ttgataaatt
     4141 gataaccagc ctgtcttcat ctagtcatgc tggtttttaa gttcatttta aatccttacc
     4201 tattctccct aactgtgcta tacttaattt atactcaatg aaaatcaaag agcaaactag
     4261 aaagctagcc gcaggctgtt caaagcactg ctttgaggtt gcagataaag ttgacgcggt
     4321 ttgaagagat tttcgaagag tattagtaca ttctttgaga ttggagttag tatgaaaatc
     4381 cataaaaccg tgaatcctgt tgcctatgaa aatacctatt atctagaagg cgaaaagcac
     4441 ctcatcgtcg tcgatcctgg tagtcattgg gaagccattc gtcagacaat cgagaagatc
     4501 aacaaaccga tctgtgctat tctcttgacc cacgcccatt atgaccatat catgagtctg
     4561 gacttggttc gcgagacgtt tggcaatcct cctgtctata tcgcagagag cgaagccagc
     4621 tggctctaca ctcctgtcga taatctctcc ggtctccctc gccacgatga tatggcagat
     4681 gtggtcacaa aacctgcaga acacaccttt gtctttcacg aagaatacca actagaggaa
     4741 tttcgtttta aggttctacc gaccccaggg cactctatcg gtggtgtttc cctagtcttt
     4801 cctgatgctc acctagtctt gacgggagat gctctattcc gcgaaactat cggacggacc
     4861 gaccttccga ctggtagcat ggagcaactc cttcatagta tccagaccca actcttcacc
     4921 ctaccaaact acgatgtcta tccaggacat ggtccagcta ctactatcgc tcacgaaaag
     4981 gccttcaatc cctttttcta gcaagatgat gacaatcgaa atttaagtaa actatccagc
     5041 aaatctttct attacaaaag gcatcctatc aaggttttca cacgtgattg gatgcctttt
     5101 ttctgatgac tagatttttt gtattaccaa ataatcacgc gctcctctgg tgaacgccac
     5161 attccgtctc cttctttgac atcataggtt gtaaagaaat cgtcgaagtt tggtacttgc
     5221 acattgacac ggagtttggc tggtgcgtgc acatcgacgc tagccaaaag tttcataaat
     5281 tctggtcgac ctttcatgcg ccagatgcga ccgaagttgt agaagaactc ttctgctgag
     5341 aagtctgctt ctctcttagc tgcttcaagc gctgctgcga ttcctcccaa gtcagccacg
     5401 ttttctgata cagtcaattt accgttaatg gttgctccat aagaatcctg tccatcaaat
     5461 tggtcaatga ctttttgtgt tttctccttg aaggcagcat agtcgctctc tgtccaccaa
     5521 tccttgaggc taccattttc gtcaaaggaa gccccgttag tatcaaaggc gtgggaaatt
     5581 tcatgggcaa tcactgcccc aataccaccg tagttagcag aagatgactg atgcaagtca
     5641 tagaaaggcg cctgtaaaat ggccgctgga aagacaatca ggttcttctg aggattgtag
     5701 taggcattga ccatatgagc aggcatgccc cattccttat agtctacagg ctggttccac
     5761 ttactccaac tgtgcttgat ttccacacgc gcaaaggcta gagcattctc aaaaagactg
     5821 gcagtttcat tcactacctt atccttgtaa cgtgcaggca attcttctgg atagccaata
     5881 taaggtttga tcacattgag cttcacgata gcctgtttac aggtttctgg agtgagccag
     5941 tcattcttaa gcagacgctc cttatagaca tcaatcatgg ttgccacttt tttctccaca
     6001 tccgccttgg cttctggaga gaacttctca cgggcgtacc aaagccccag ggcttgcttg
     6061 aaaggttcct gtgctagatg ataagctgct ttgaccttat cttttgcctc tggaactcca
     6121 gaaagggcac ggctgtaggc accagacaaa acacggatat cctctgttaa atagctggtt
     6181 gaaagattga caacactcaa aatcaaggtt gctttaagga gagaccaggc ttcctcactg
     6241 taaaattgct ctgctgcttg ccagaaacgt tcctcgtcta caataacctt gtctggtaat
     6301 tgcccaataa ctgctttgaa gaagtcatcc aaaggtaggg caggcgcgaa tttcttgaaa
     6361 tcttcgtaag aatatggatg atagagttta gcatattctg aactttcttc attagagagc
     6421 accactgccg caactcggcg gtccaattca agtctttttt ctagcaagtc ttcaatttct
     6481 tcatcagaga aatcataagc cttgaggaga tttgcgctgc tttctttcca aagagtcaag
     6541 agctcttcgc gctgaggatg ttcttctgca tagtaggtcg tatctggcaa gattgtgctt
     6601 ggagcgctag cccatagaac attgattcta gcatccataa agtctggcga tacaccaaaa
     6661 ggaaggaagt ttggttttcc tgcaagctca aactctgcta gtttagctgt aaaatccgca
     6721 aaagtttcca attcttggaa ttctttaagg agtggtaaga caggtgtgat accgtcagct
     6781 tctctcttgt caaaatcacg aactaggcgg tggtatttga caaagttttc caagatagca
     6841 tcctcaggca cttcttcacc tgctaaccac ttgtctgttg tcgccagcat caggtcttca
     6901 atttcctggt ctaaatcaac aaaacctcct gtttgagact tatctgctgg gatttcagct
     6961 gtctgttgcc attctccatt gatagcatca taaaaatcat cttgataacg tgtcatcttg
     7021 ttctcgcttt catttgtatt tgcatttatc ttaacaaaaa tcactaggga atgcaattaa
     7081 taaccattta actattattt tttagctatt ataaaaaacc tttccatgat aaaacgcata
     7141 attccaagtt ttttacactt gatactatgc gttttataat ttagaaattt atcctgaaag
     7201 ttatctttag aatctatttt
//
LOCUS       DAVBIC010000074         7162 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.074, whole genome shotgun sequence.
ACCESSION   DAVBIC010000074 DAVBIC010000000
VERSION     DAVBIC010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7162)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7162)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7162
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.074"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            complement(741..1001)
                     /locus_tag="VQ664_001975"
     CDS             complement(741..1001)
                     /locus_tag="VQ664_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2790075.1"
                     /translation="MRERSATGAQGLSKSIKKHLNDLTRLTASLLGDEKLSAITSSSA
                     VKADIHRFVIELEPVKSTILQNDDISLDQNEIFEILKNFLDG"
     gene            complement(1060..1611)
                     /locus_tag="VQ664_001976"
     CDS             complement(1060..1611)
                     /locus_tag="VQ664_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2790076.1"
                     /translation="MPANTKVIFQEMFADFQNYYVLIGGTATSIVLDSQGFKSRTTKD
                     YDMVIIYEVKNKEFYTTLNHFLELGEYQGSQKDEKAQLFRFTTTNPEFPSMIELFSIL
                     PEYPLKKDGREIPLHFDQDASLSALLLDEDYYNILVHEKETIQGYSVLSNCGLYSSKI
                     SSNHVSFHLQPQNSVLSSLQLAS"
     gene            complement(1601..1798)
                     /locus_tag="VQ664_001977"
     CDS             complement(1601..1798)
                     /locus_tag="VQ664_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2790077.1"
                     /translation="MLEIWKYRPFVSEFWNDFKNNHDKQFVDPISLYLTLKDDDDPRI
                     EEESEALENMILQYLGEDDAS"
     gene            complement(1802..2386)
                     /locus_tag="VQ664_001978"
     CDS             complement(1802..2386)
                     /locus_tag="VQ664_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2790078.1"
                     /translation="MNVKKIMSIFQSFYVDVSIEELTLTLPISFVKRFEYTQMTFHKE
                     SFLLIKEKRRGSLSSFVTQARTMGEKANMDVVLVFSKLSDSEKKQLLQARVPFVDFKG
                     NLFFPPLGLVLNANDTEIPKELTPSEQLTWIAFLLPDGDIKQIKSVSNLLYGGAYALS
                     HSTFLAETDENTSYVIWQRKFNQLSLPLSQHVLK"
     gene            complement(2794..3219)
                     /locus_tag="VQ664_001979"
     CDS             complement(2794..3219)
                     /locus_tag="VQ664_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000204059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2790079.1"
                     /translation="MTSRVFIDADCISAFLWVGTEHLLEKLYSGKIVIPQEVYDEINI
                     PTIPHLKSRIDQLVTKGSAEIVSIDIGTEEYALYRDLTRNYDSNKIIGKGEATSIFLA
                     KKHNGILGSNNLRDVKPYVEEFSLEHMTTGDILIEAFKA"
     gene            complement(3212..3706)
                     /locus_tag="VQ664_001980"
     CDS             complement(3212..3706)
                     /locus_tag="VQ664_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2790080.1"
                     /translation="MKKSSVSLILIGEGDETERKADQFASYFLIFPSSLYRMVEEIRE
                     NANRTHLEVEDIIKLGQFYGISHKAMLYRLRNDGYLDAEEIKNMDISVIETASRLGYD
                     TSLYRPLSESKKEMVLGHYIKSTEQLLENNRISQGKYEELLLDAFRYDIVYGLDEEGE
                     LSFD"
     gene            complement(3752..3958)
                     /locus_tag="VQ664_001981"
     CDS             complement(3752..3958)
                     /locus_tag="VQ664_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2790081.1"
                     /translation="MDLSNKASNLRKKLGADGESPIDIFKLVQKIENLTLVFYGLGKN
                     ISGVCYKGTQFSLIAVNSDMPLGR"
     gene            complement(3945..4106)
                     /locus_tag="VQ664_001982"
     CDS             complement(3945..4106)
                     /locus_tag="VQ664_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2790082.1"
                     /translation="MNMINVCDVGKRIKELRISSNLTQDKIAEYLSLNQSMIAKMEKG
                     ERNITNGFK"
     gene            complement(4471..5427)
                     /gene="lytA"
                     /locus_tag="VQ664_001983"
     CDS             complement(4471..5427)
                     /gene="lytA"
                     /locus_tag="VQ664_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HET2790083.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKHDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPDFTVEPEGLITVK"
     gene            complement(5803..7155)
                     /locus_tag="VQ664_001984"
     CDS             complement(5803..7155)
                     /locus_tag="VQ664_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HET2790084.1"
                     /translation="MDLIHGPILPSLLSFTFPILLSNIFQQLYNTADVLIVGRFLGQE
                     SLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWILGALLSI
                     LVMLLGFLGLYHLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLRSIGDSL
                     AALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRKSVPELL
                     PQFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQFSVNTFGAVIISAQTAARRI
                     MTFALLPMTAISASMTTFASQNLGAKRPDRIVQGLRIGSRLSISWAVFVCIFLFFASP
                     ALVSFLASSTDGYLIENGSLYLQISSAFYPILSLLLIYRNCLQGLGQKILPLVSSFIE
                     LIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAILATKVQS
                     "
BASE COUNT         2298 a         1486 c         1132 g         2246 t
ORIGIN      
        1 tggtttcgca ggaagtctat tatatatgca cagacatatg aaatcttttt gagacagcag
       61 ttatgatata tttatccatt cacaacatct tctgtactaa tactacaata ttggtacatt
      121 ttgattacac aatcgtttca aaaaatatga tggaagcctg agtattttat agtaattccc
      181 ttcctatcaa ctagatcaac cagttgagtg ttgaatgttg aaacacccta gcctcagcaa
      241 aggactatga tcagcatttc ctagccaata ggacgctcca aatcacctat tctaagtcca
      301 tcactagctt ggtcagtaag atacagactg caaggcgaga ctgacgtggt tgatgagatt
      361 ttggaagagt attacaatca tagattcacc agtagacttg accgcagatt taactatagt
      421 agattgaaac tagaatagta catctctgct tctaaaacat tgttagaaat cgatttgact
      481 gtcctgatca atttgtcctg ttctcgtttc atttcactat actaaaaaac cacctgaaac
      541 aaatcaagtg actagaggat aaaaacaaag actaggcaaa aagttttgaa aagcaaaaaa
      601 cgcataatat caggtcttga aaaaccttga tactatacgt ttgattgtgg gaagattgac
      661 ttcattttct cctgaaattg aagttttttc tagtttccag atatagacga attcaatata
      721 gccatctcgc tacaattatt ttaaccatcg agaaaatttt tcagaatttc aaaaatttca
      781 ttttgatcca atgaaatgtc atcattttga agaatagttg acttcacagg ctctaattct
      841 atcacaaagc ggtgtatgtc tgcttttacc gcactacttg atgttatagc cgataacttt
      901 tcatctccta gcaaggaagc tgtcaaacgg gtaaggtcat tcaaatgctt tttaatggac
      961 ttacttaaac cttgagcacc tgtagcagag cgttccctca tatccagcca agctttagcc
     1021 ttaaaaataa ttaatactca atgaaaatca aagagcaaac taggaagcta gctgcaggct
     1081 gctcaaaaca ctgttttgag gttgtagatg gaagctgacg tggtttgaag agattttcga
     1141 agagtataaa ccacaattac tcaataccga atacccctga atggtttctt tttcatgcac
     1201 caatatatta taataatctt catccaataa taaggctgat aaactagcat cttggtcaaa
     1261 atgtaaggga atttctcgac cgtccttctt taatggatat tctggtaaga tactaaatag
     1321 ttcaatcata gaaggaaact caggattagt tgttgtaaat cgaaaaagct gcgctttctc
     1381 atctttctga cttccttgat actctcccaa ttctaaaaaa tgattcaagg tagtataaaa
     1441 ttccttattt tttacttcat aaatgatgac catatcataa tcttttgttg tgcgactttt
     1501 aaatccttgc gaatccaata cgatagaggt agcagttccc ccaatcagaa cataatagtt
     1561 ctgaaaatcc gcaaacattt cttgaaaaat aactttcgta ttagctggca tcatcttctc
     1621 ccagatactg taatatcata ttttctagtg cttcactctc ttcctctata cgtgggtcat
     1681 catcatcttt taaggtcaaa taaagagaaa tcggatctac aaattgttta tcatgattat
     1741 ttttaaaatc attccaaaac tcagatacaa aaggacgata tttccatatc tctagcatct
     1801 ttcattttaa aacatgctga gaaagtggca aggataactg attgaatttt ctctgccata
     1861 tgacatagct agtattttca tccgtttcag ctaaaaaagt tgaatgcgac aaagcataag
     1921 caccaccata tagaaggtta gaaacagatt ttatctgctt tatatcgcca tctggcaata
     1981 aaaaggcaat ccacgttaat tgttcgctag gtgttaattc cttagggatt tcagtatcat
     2041 tcgcattgag tactagtccc aatggaggga agaagaggtt tcccttaaag tctacaaacg
     2101 gaactctagc ttgaagtaat tgcttttttt cactgtctga taacttcgaa aacaccaaaa
     2161 caacatccat attggctttt tcacccatag tgcgagcctg agtaacaaat gaactcaaac
     2221 tcccccttct cttttcttta atcaataaaa atgattcctt atgaaaagtc atttgagtat
     2281 actcaaacct ttttacaaaa ctgattggta aagtcaaagt cagttcctca atactgacat
     2341 caacataaaa ggattgaaaa attgacatta tctttttgac attcatgttt tttccttatt
     2401 ctatcatttt tattatattt tatcattcgg tataataaaa tataagtttt ttgataaaat
     2461 aaccaaaaac tactcgctat cccctctcac attaccctac atatcgtttg acatgcgact
     2521 gatagttcag gaaaacttca aggagaactt ttctctcatc cactatgcag gacttactat
     2581 ttcacttcta ctcctatagg ctcaatttga cacttttctt tttcgaattg ctcatatgcc
     2641 tcctgaatag tgagttcgat ttatccaaat ttatttttgt ctattttgat gaatacttcc
     2701 acgaagatag tctgaaaatg aatttgcacc aattttcctt ctctttttaa gcatattatt
     2761 ccagatatga ttgccctctt gttcagtaat aaattacgct ttaaacgctt caatcagtat
     2821 atctcctgtt gtcatatgtt ctaaagaaaa ttcttctaca tatggtttaa catctcttag
     2881 gttattactt cctaatatcc cattatgctt tttcgctaag aaaatagaag tcgcttctcc
     2941 cttaccaata atcttgttac tatcataatt tcttgttaaa tctctatata atgcgtattc
     3001 ttcagttcca atgtctatgc tcacaatctc agctgaaccc ttagttacca actggtctat
     3061 cctagatttt aaatggggaa ttgtaggtat attgatttca tcatacacct cttgtggaat
     3121 aacaatttta cccgaataga gcttttctaa aagatgttca gtgccaaccc ataaaaatgc
     3181 tgaaatacaa tctgcatcaa taaatacacg actagtcaaa cgacaactcc ccctcttcat
     3241 ctagcccata tacaatatca tatctgaaag catctagtaa cagttcctca tacttccctt
     3301 gcgaaattct gttattttct aaaagttgtt cagtcgattt aatatagtgc cctaatacca
     3361 tttccttttt actttctgac aaaggacgat ataaacttgt atcatagcct aatcttgaag
     3421 ctgtctctat aacactaata tccatatttt taatttcttc tgcatcaagg tatccatcat
     3481 ttctcaatct atataacata gctttatgac tgataccata aaactgaccc aattttataa
     3541 tatcttctac ttcaagatga gttctattgg cattttctct gatttcctca accatcctat
     3601 acagtgaaga tgggaaaatt aaaaaataag aagcaaactg atccgctttt ctttcagttt
     3661 catctccttc accaatcaag ataagactga ctgaactctt cttcacctca tcataataaa
     3721 gatgatacag tccatgtgct aaagaaaatc tttaccttcc taatggcatg tctgaattga
     3781 ctgcaatgag actgaactga gttcctttat aacagactcc gctaatattc tttccgagtc
     3841 cataaaatac cagcgtcaaa ttttctatct tttgtaccaa tttaaaaata tctatcggcg
     3901 attcaccatc agctcccaac ttttttctaa gatttgaagc tttattactt aaatccattc
     3961 gtgatattcc tttcaccttt ttccattttg gcaatcatgc tttgattcaa agacaaatac
     4021 tcagcaatct tatcttgagt aagatttgaa gatattctaa gttcttttat tctttttcca
     4081 acatcacata catttatcat attcatacac ctctcataaa aagaatagca cattcttgtc
     4141 ataatttttt aaataaaaaa attatgacaa aacaaggaag caatttattg atgctactta
     4201 aaaatctaaa attgatgata ttaaacctat ttgatgagtt cctatcaaaa atcgtatctt
     4261 caacctcaaa acagtactta aagctatccg actcggttta cattgtcaaa tttagatttt
     4321 atttgagcat aactttctag tttgcttttt gatttttgtt taatatagta acaaaaattg
     4381 aaggaaatat ctccacaaga aaacgcatac tattaagctt tttcaagacc taataatatg
     4441 cgctgttctg atttgaaaga cattccatta ttattttact gtaatcaagc cttcaggctc
     4501 tactgtgaag tctggcttgt ctgccagtgt tccgtctggt ttgaggtagt accagcctgt
     4561 tccgtccgct gactggataa aggcatttga taccatggcg ccttctttag cgtctaagta
     4621 gtaccaagtg tccttgtact tgacccagcc tgtcttcatg gcaccttctt cgttgaaata
     4681 gtaccactta tcagcgattt tcttccagcc tgtagccatt tcgcctgagt tgtcgaacca
     4741 gtaccagttg ccgtctgtgt gcttcctcca gcggtctgca agcatatagc ctgaactgtc
     4801 aaagtagtac caagtgccat tgattttctc aaacttgtct tttggataag agccgtctga
     4861 atgtacgtac cagtagccag tgtcattctt ctgccagcct gtttcaatcg tcaagccgtt
     4921 ctcaatatca tgcttaaact gctcacggct aatgccccat ttagcaagat atggataagg
     4981 gtcaacgtgg tctgagtggt tgtttggttg gttattcgtg caatactcgt gcgttttaat
     5041 tccagctaaa ctccctgtat caagcgtttt cggcaaacct gcttcatctg ctagattgcg
     5101 taagagttcg atataaaggc ggtagtccgt catgaactct tctttggttg aatggctttc
     5161 aatcagttca accgctgcat aggtctcagc attccaaccg cccccaacgt cccaggcacc
     5221 attatcaaca ggtcctacct gcatgatgca accgttccca acaatgtgcg agaaaaaacc
     5281 taattctggg tctttccgcc agtgataatc cgcttcattc tgtacggttg aatgcggatt
     5341 cccagttgag tgtgcgtgta cttgcctata tggttgcacg ccgacttgag gcaaatctgt
     5401 tcttaattta ctcacattaa tttccatatt ctactcctta tcaattaaaa caactcattt
     5461 tttacaatcc agaaccagaa actcctttat ttctacctta caaagaagac aatcttagtc
     5521 acgattaagc ttgtagatag aacctcaaaa cgcactattt tgacactgta aataggactg
     5581 acaaggtctg cattctatct acaataacac cccagactaa aaagcttttc aaaagtatat
     5641 ttttacagtc tctatatgtc cttttcataa atactatact ttattatatc acataaaaga
     5701 agtcaaaagt ctgttaaact attttcaaca ccaaactaaa gaagagaaca caagtttttt
     5761 cgatgttcac tagaggaaat ggattttatt cagtaaatcc aactaggatt gcactttggt
     5821 tgccaaaatt gcctttcctt cttttatcaa gggatgacgg aatagtgaga agtacagttg
     5881 aactgtcatg gcaacccaga taagaggttc acaaaggata acacccttat atcctgccca
     5941 aggaataatc aaaaccacaa aaacgatttt tccgattagt tcaataaagc tagaaactag
     6001 aggaaggatc ttctgcccca agccctgcaa gcaattgcga taaatcaaca agaggctcaa
     6061 aatgggataa aaggctgaac tgatttgcag atagagactt ccattttcta tcaagtaacc
     6121 atctgtcgaa ctagccaaga aggaaaccaa ggctggactg gcaaaaaaga ggaaaataca
     6181 aacaaaaact gcccaggata tacttaaacg actgccgatt cgaagacctt gaacaatgcg
     6241 gtcaggtcgc ttagctccta gattctgaga agcaaaggtc gtcattgatg cagaaatagc
     6301 ggtcatagga agaagggcaa aggtcataat gcgtcgagct gccgtctggg cactaataat
     6361 cactgcacca aatgtattaa cagaaaactg taaaatcaca ctgccgatag atacaattga
     6421 actcatcaag cccatagcca aaccttgctc caagagatcc gcgtacaagc ttttgtccca
     6481 tttgaaatgt ttaaactgtg gcaagagttc tggcacactt ttacgaatat aataaaagca
     6541 gagaaccgct gataaacctt gcgaaataat ggtagcaagt cctgcggatt gaactcccag
     6601 atgcaattgc gtaataaaat agagatccag aaccacatta accaaggcag agaaaatcag
     6661 aaatcccagg gctgctagac tgtcaccaat agaccgcaac aagcctgcaa aaagattata
     6721 agcaaagctg acacctacac aggtcacaat catagaaata tattgataag attgaggaag
     6781 aatttctgca ggagtatcta agtattgcaa gagatgatac aagccaagaa agcccagcaa
     6841 cataactaga atgctcaaaa gagcacctaa aatccaagta gctgctactg cttccttgat
     6901 tttagtgaaa ttccgagccc cataataacg agcaatgaca atccccatgc cattgccaac
     6961 accaagtgta aaacctacaa tcaggtcaaa aatcgctgtc gtcgctccta ctgcagccaa
     7021 ggattcttga ccaagaaatc gtccaacaat caagacatca gcagtgttat agagctgttg
     7081 aaaaatattt gatagcaaaa ttggaaaggt gaagcttaag agcgagggaa gaatcggacc
     7141 atgtatcagg tccactgttc gt
//
LOCUS       DAVBIC010000075         6925 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.075, whole genome shotgun sequence.
ACCESSION   DAVBIC010000075 DAVBIC010000000
VERSION     DAVBIC010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6925)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6925)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6925
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.075"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            <1..1647
                     /locus_tag="VQ664_001985"
     CDS             <1..1647
                     /locus_tag="VQ664_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HET2790085.1"
                     /translation="NYRTDKTAMWALSGNFDASKSWKKEELELANWISKNYSINPVDN
                     DFRTTTLTLKGHTGHKPQINISGDKNHYTYTENWDENTHVYTITVNHNGMVEMSINTE
                     GTGPVPFPTPDKFNDGNLNIAYAKPTTQSSVDYNGDPNRAVDGNRNGNFNSGSVTHTR
                     ADNPSWWEVDLKKMDKVGLVKIYNRTDAETQRLSNFDVILYDNNRNEVAKKHVNNLSG
                     ESVSLDFKEKGARYIKVKLLTSGVPLSLAEVEVFRESDGKQSEEDIDKITEDKVVSTN
                     KVATQSSTNYEGVAALAVDGNKDGDYGHHSVTHTKADSNAWWQVDLGEEFTVSKVDIY
                     NRTDAEPQRLSNFDVIFLSSSGEEVFRRHFDKVVDGLLSLKVPSVGAKLVKIELKSAA
                     IPLSLAEVEAYGSKRTPKKLSNIALTKETRQSSTDYNGFSRLAVDGNKNGDYGHHSVT
                     HTKGDSPSWWEIDLAQTEELEKLIIYNRTDAEIQRLSNFDIIIYDSNNHEVFKQHIDS
                     LESNNLSIDLKGLKGKKVRISLRNAGIPLSLAEVEVYTYK"
     gene            1704..3470
                     /locus_tag="VQ664_001986"
     CDS             1704..3470
                     /locus_tag="VQ664_001986"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HET2790086.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAIWGFNGTERPGAVYLAAVLASHAQKGIPAFGIYGRDVQEANDTDIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRG
                     IYDPEEFERAMVWVKEHIKEGVDRNREDLILSKEEKEKQWEFVIKMFMIGRDLMVGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVKRVTGHTLEGCAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELEESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDSGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYRACQLLGPLHK"
     gene            3616..4767
                     /locus_tag="VQ664_001987"
     CDS             3616..4767
                     /locus_tag="VQ664_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HET2790087.1"
                     /translation="MAIFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKTLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHRCDFIISLGGGSPQDAA
                     SCISIMATNGGKPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPQALTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVENGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIEHENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIVEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            4912..5796
                     /locus_tag="VQ664_001988"
     CDS             4912..5796
                     /locus_tag="VQ664_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HET2790088.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            6195..6446
                     /locus_tag="VQ664_001989"
     CDS             6195..6446
                     /locus_tag="VQ664_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HET2790089.1"
                     /translation="MKEFQFERKQRFSLRKYAIGACSVLLGTSLFFAGMGDQPVQDTE
                     TSSALISSHYLDEQDLSEKLKSELQWFELENKLLNLWEH"
     gene            6434..6724
                     /locus_tag="VQ664_001990"
     CDS             6434..6724
                     /locus_tag="VQ664_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2790090.1"
                     /translation="MGALGYYEGFVPYVSNQYKNQAEEEGKPLSDKYIFEKILGKTYA
                     AFKKDQINERVEKLGKLKPITINYNGKSEVIDSKEKLQELMNKAVKDEVAQI"
BASE COUNT         2283 a         1136 c         1497 g         2009 t
ORIGIN      
        1 aattacagga cagataagac agctatgtgg gcattatcag gaaattttga tgcatcaaaa
       61 agttggaaga aagaagaatt agagttagcg aactggataa gcaaaaatta ttccatcaat
      121 cctgtagata atgactttag gacaacaaca cttacattaa aagggcatac tggtcataaa
      181 cctcagataa atataagtgg cgataaaaat cattatactt atacagaaaa ttgggatgag
      241 aatacccatg tttataccat tacggttaat cataatggaa tggtagagat gtctataaat
      301 actgaaggga caggcccagt ccctttccca acaccagata aatttaatga tggtaatttg
      361 aatatagcat atgcaaaacc aacaacacaa agttctgtag attacaatgg agaccctaat
      421 agagctgtgg atggtaacag aaatggtaat tttaactctg gttcggtaac acacactagg
      481 gcagataatc cctcttggtg ggaagtcgat ttgaaaaaaa tggataaagt tgggcttgtt
      541 aaaatttata atcgcacaga tgctgagact caacgtctat ctaattttga tgtgattcta
      601 tatgacaata atagaaacga agttgctaag aaacatgtta ataatttgtc gggtgaatct
      661 gttagtctag atttcaaaga aaaaggagca aggtatatta aagttaaatt actaacgagt
      721 ggagtgcctt tgagtttagc agaagtagag gtttttagag aatcagatgg taagcaatct
      781 gaagaggata tagataaaat aacagaagat aaagtagtct ctacaaataa ggtagctact
      841 caaagttcaa ccaattatga gggtgtagct gctttagcag ttgatggtaa taaagatgga
      901 gattacggac atcattcggt gactcatact aaggcagatt ctaacgcttg gtggcaggtc
      961 gatctgggag aagagtttac ggtttctaaa gttgatattt ataatagaac agatgccgaa
     1021 cctcagcgtt tatctaattt tgatgttatt tttctatctt catcaggaga agaagttttt
     1081 agaagacatt ttgataaagt agttgatggt ttgttatctt taaaagtacc ttctgtaggg
     1141 gctaagctag tcaaaataga attaaaatca gcagctattc cgttaagttt agcggaagtt
     1201 gaagcctatg gttcaaagag aactccgaag aaactttcta atattgcatt aaccaaagaa
     1261 actcgacaga gttcaacgga ttacaatggt ttttctcgtc tagcagttga tggaaataaa
     1321 aacggagatt atggtcatca ttcagtgact cataccaaag gagattctcc ttcatggtgg
     1381 gagatagatt tagcacaaac cgaagaatta gaaaagttaa ttatttataa tagaacagat
     1441 gctgaaattc agagattatc aaattttgat attattatat atgattcaaa taatcatgaa
     1501 gtttttaaac aacatattga cagtttagaa agcaataatc tatccataga cttaaaaggg
     1561 ctgaagggaa aaaaggttag aatttctttg agaaacgcag gaattccttt aagtttggca
     1621 gaggtagagg tttatactta taagtaattt taaaaattat catcggtagt atgaaagaaa
     1681 cagaaaaata agaggaaaat agtatgattc aacatccacg tattgggatt cgtccgacta
     1741 ttgatggtcg tcgtcaaggt gtacgcgaat cacttgaagt acaaacaatg aacatggcta
     1801 aaagtgtggc agatttgatt tcaagcacat tgaaatatcc agatggggaa cctgtggaat
     1861 gtgtgatttc tccatctacc attggtcgtg ttccagaggc tgcagcttcc catgagttgt
     1921 ttaaaaaatc aaatgtttgc gcaacaatta cagttacacc atgctggtgt tatggtagtg
     1981 aaactatgga tatgtctcca gatattcctc atgctatttg gggatttaat gggacagaac
     2041 gcccaggagc tgtctatctt gcagctgtac tagcttcaca tgctcaaaaa gggattccag
     2101 cctttgggat ttatggtaga gatgttcagg aagctaatga tacagatatt ccagaagatg
     2161 tcaaagaaaa acttttacgt tatgcgcgtg cagctcttgc aactggcttg atgagagaca
     2221 ctgcttacct atcaatgggt agtgtttcga tggggattgg cggttctatt gtaaatccag
     2281 atttcttcca agaatactta ggaatgcgaa atgaatcggt agatatgacg gagttcacgc
     2341 gccgtatgga ccgtggtatt tatgacccag aagagttcga acgtgctatg gtttgggtaa
     2401 aagaacatat caaagaaggg gttgaccgaa atcgtgagga tttgattctt tctaaagaag
     2461 agaaagaaaa acaatgggaa tttgttatta agatgttcat gattggacgt gacttaatgg
     2521 ttggtaaccc aaggcttgct gaacttggtt ttgaggaaga agcggttggt caccatgctt
     2581 tagtagctgg tttccaaggt caacgtcagt ggacagacca ttttccaaat ggagatttta
     2641 tggaaacttt cctcaatact cagtttgact ggaatggtat tcgaaaacca tttgtatttg
     2701 cgacagagaa tgattcacta aatggtgtgt ctatgctctt taattatcta ttaacaaata
     2761 ctccacaaat ctttgctgat gtgcgcactt attggagtcc agaggctgtt aaacgtgtaa
     2821 cgggacatac tttagagggt tgtgctgcag ctggcttctt acatctaatc aactctggtt
     2881 cttgtacatt ggatggtaca ggtcaagcta ctcgagatgg caaacctgtt atgaaaccat
     2941 tctgggagtt ggaagaaagt gaagtacagg ctatgcttga aaatacagac ttcccaccag
     3001 caaaccgcga gtacttccgt ggaggaggat tctcaactcg tttcttgacg aagggggata
     3061 tgccagtaac aatggtacgt ctcaatcttc taaaaggggt tggtccagtg ctacaaattg
     3121 cagaaggtta cacacttgaa cttcctgaag atgttcacca tactttagat aatcgtacag
     3181 attcaggatg gccaactact tggtttgctc cacgtttgac aggaaaaggt gctttcaagt
     3241 ctgtctatga cgtcatgaat aattggggag ctaatcacgg agccataaca tatggacaca
     3301 ttggagcaga cttgattacc ttggcttcta tgttgagaat tcctgtcaat atgcataatg
     3361 tacctgagga agatatcttt agacctaaaa attggtcctt atttggaaca gaagatctag
     3421 aatcagcaga ctatcgtgca tgtcagttgt tgggaccact acataaataa aacttgttta
     3481 tataggaggt gaacttacgt ccctcctatc cttttaaaaa gatttgttaa acaattcaca
     3541 aataattgaa aacgaataca aaaagtaata taatgatgtt aaatagatag cgcggaggcg
     3601 caggaggaaa attatatggc tatattttat gttccggcag tcaaccttat tggaaaaggt
     3661 gttgtaaatg aagtgggtcc ttatatcaag gaacttggct ataaaaaggc acttttggtg
     3721 acagataagt acatcgaagg cagtgatatt ttacctaaga ctttaaaacc actggataca
     3781 gaaggaatcg aatatgtcat ctttagcgat gtagagccaa accctacttg taaaaatgtc
     3841 acagatgggg tagctgcttt gcaagaacat agatgtgatt ttatcatcag tcttggcggg
     3901 ggttctccac aggatgcagc tagttgtatt tctatcatgg ctacaaatgg tggaaaacca
     3961 caggattatg aagggcttca taagtctgct aaaaaaggct tgccggttgt ggctatcaat
     4021 acaacggcag gtacatcagc agaaatcact attaactatg tgattactga tgaagaacgc
     4081 aaggttaaga tggtaatggt tgacaagaat agccttgcct tgatttctgt caatgaccct
     4141 gaactcatgc tttccaaacc tcaagccttg actgctgcta ctggtatgga tgctctgact
     4201 cacgctgttg aagctttggt aacacctggt gcttatgatg taaccaagaa actgtctatt
     4261 ggtgctattg agcttatcaa ggaatatctt cctcgtgctg tagaaaatgg acatgatatt
     4321 gaagcgcgtg aaggtatggt caatgccatc ttccttggtg gtatgagctt taataatgct
     4381 ggtcttggtt atgttcactc aatggctcac caactcggtg cagtatataa tttgccacat
     4441 ggtgtttgct gtgccatgtt gctaccagtt atagaacatg aaaatgctaa acgtgtacca
     4501 gaagctttcc gcaatgttgc caaagccttg ggacttcatg tagaaggtaa atcagatcaa
     4561 gaatgtgccg attatgcgat tgttgagatt gagaagcttt ctgagacagt aggtattcct
     4621 aagaaactga ctgaacttgg tattgaagaa aaagatttcg actttgaata cctttctaag
     4681 aatgccttga ttgatgcctg cgcaccagga aatccattta tgccaacctt agaagaaacg
     4741 attgcctttt ataaagagtt attttagcaa gagattggac gacaatagga caattcacct
     4801 ctaattattg acatttcagg aaaaatcgca gtaaaaacgg cacagccttc tttaaatgtg
     4861 ctataatact agaaaaatac ttgtggaggt tccattatgg caatattttt catgattttt
     4921 ctgattgttt gtgtgctcct attggtgata gtcacactga gtacagttta tgtggttcgt
     4981 cagcagtcgg tggcgattat tgaacgcttt gggaaatacc aaaaggttgc taatagcggt
     5041 attcatattc gcttgccttt tgggattgac tcgattgcag cacggattca gttgcgcttg
     5101 ttgcaaagtg atattgtggt tgagactaag accaaggaca atgtgttcgt tatgatgaat
     5161 gtagcgactc agtaccgtgt caacgagcag agcgtgacag atgcttacta taaactcata
     5221 cgtccagaat ctcagattaa atcttatatc gaagatgctc ttcgctcttc tgttccaaaa
     5281 ttaaccttgg atgaattgtt tgagaaaaaa gatgagattg cccttgaagt tcaacaccaa
     5341 gtagcagaag aaatgaccac ttacggctac attatcgtga aaaccttgat taccaaagtc
     5401 gaaccggatg cagaagttaa gcaatccatg aatgaaatca atgcggcgca acgtaagcgg
     5461 gtcgcagcac aagaattggc ggaagctgac aagattaaaa ttgtcactgc agctgaagca
     5521 gaagcagaaa aagaccgcct tcatggtgtg gggattgccc aacaacgtaa ggcgattgtg
     5581 gatggattgg cagagtctat caccgaactc aaggaagcca atgttggcat gacagaagaa
     5641 caaatcatgt ctatcctctt gaccaaccag tatttggata ccttgaatac ctttgcctct
     5701 aaaggaaatc aaaccatctt tttaccaaat acgccaaatg gtgtggatga tatccgaaca
     5761 caaatcttgt cagcccttcg cgctgagaag aaataataga ctaatactct tcgaaaatct
     5821 cttcaaacca cgtcagcgtc gccttgccgt atagatgtta ctgactttgt cagttctatc
     5881 tgcaacctca aaacagtgtt ttgagctgac ttcgtcagtc ttatctacta cctcaaaacg
     5941 gtgttttgag caacctgtgg ctagtttcct agtttgctat ttgattttca ttgagtacaa
     6001 agagcttggc aacaggctct ttttgtattg cgtttattaa gaaaaacaaa aaacatagat
     6061 atacatttaa ctaaaaatta ttgtatgtta cctcccttaa ttaggaatga taagggaata
     6121 actagaaaga tttgtgaata caaactattt ctgatataca aaatatacag taataatgaa
     6181 tgatgggaga tgggatgaaa gaatttcaat ttgagagaaa gcagcgtttt tctttgagga
     6241 aatatgcaat aggagcttgt tcggtcttgc taggaacgag tttatttttt gctggtatgg
     6301 gtgatcagcc tgtacaggat acagaaacga gttcagcact aatttcaagt cattatttgg
     6361 atgagcagga tttatctgaa aagctgaaat ctgagttgca atggtttgaa ttagaaaaca
     6421 agcttttgaa cttatgggag cattaggtta ctatgaagga tttgttcctt atgtttcaaa
     6481 tcaatacaaa aaccaagctg aagaagaagg caaaccgcta tctgataaat atattttcga
     6541 aaaaatctta ggaaaaacat atgcagcctt caaaaaagat caaattaatg agcgtgtcga
     6601 gaaattaggt aagttaaaac ctattacaat aaattacaac ggaaaatcag aagtaattga
     6661 tagtaaagaa aaattacaag agcttatgaa taaagccgtt aaagacgaag tggctcaaat
     6721 atagtaaaat gaaataagaa caggacaaat cgttcaggac agtcaaatcg atttctaaaa
     6781 atgttttaga agtagaggtg tactattcta gtttcaatat actataaaat caggcaatac
     6841 cacggctaaa aagtttgagt ttatcgaaac accagtgcaa aaactgaaaa aagcgattta
     6901 taaagctcat ctcaaagatt cagat
//
LOCUS       DAVBIC010000076         6889 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.076, whole genome shotgun sequence.
ACCESSION   DAVBIC010000076 DAVBIC010000000
VERSION     DAVBIC010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6889)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6889)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6889
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.076"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            <1..316
                     /locus_tag="VQ664_001991"
     CDS             <1..316
                     /locus_tag="VQ664_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2790091.1"
                     /translation="ELIAPMTYEETMTSDFFEVWFQKFFLPTLTTPSVIIMDNVRFHR
                     MGKLELLCEEFGHKLLPLPPYSPEYNPIEKTWVHIKKHLKKVLPSCNTFYEALLSCSC
                     FN"
     gene            377..1339
                     /locus_tag="VQ664_001992"
     CDS             377..1339
                     /locus_tag="VQ664_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HET2790092.1"
                     /translation="MNMSNITIDGQEMDLSQTMPSYAQVVSLYDDTSISVSSNETDKV
                     LAGSLYTDTNEQGLTIPSSLLKNWNEQTGKNLTANDLIGKSVSASIVESAAETSKIAQ
                     FQTKIVRVINDEDDMEDSNSFMLSHQMETILKEAGFTKAVSYFILELKDPSQTKVVTE
                     ELQKNKKYTVLSQQRVLDIVIIFIRVIQGLLIVLSSQAIVVAAVMIGIIIYINIMQRS
                     KEIGVMKAVGYQNRDVKGIFIYEAIWIVGIALLLAFLVAQGVGSLANAIVSHFYPSIT
                     KVFELNLLSVLGTLVFALLLGYVSAYFPARKISKMDPVEPLRYE"
     gene            1516..2523
                     /gene="gap"
                     /locus_tag="VQ664_001993"
     CDS             1516..2523
                     /gene="gap"
                     /locus_tag="VQ664_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HET2790093.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFIKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHDVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(2590..3426)
                     /locus_tag="VQ664_001994"
     CDS             complement(2590..3426)
                     /locus_tag="VQ664_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HET2790094.1"
                     /translation="MTVKQLLEEQLLIPRKIRHFLRIKKHILINQEEVHWNEIVNPGD
                     VCQLTFDEEDYPQKTIPWGNPDLVQEVYQDQYLIIVNKPEGMKTHGNQPNEIALLNHV
                     STYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISREYWALVDGNINRK
                     ELVFRDKIGRDRHDRRKRIVDAKNGQYAETYVSRLKQFSNKTSLARCKLKTGRTHQIR
                     VHLSHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLEKLTFTTLSNTFEKELKK
                     NG"
     gene            3552..5747
                     /locus_tag="VQ664_001995"
     CDS             3552..5747
                     /locus_tag="VQ664_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HET2790095.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVELTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLQNMVAAGYI
                     DKNQETEAAEVDMASQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQIVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYDSYKVDNYAGI
                     KTSREVPMYQALAESLNLPAVAAVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIASHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYIMAGKTGTTEAVFNPEYTSDQWVIAYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            5800..5952
                     /gene="rpmG"
                     /locus_tag="VQ664_001996"
     CDS             5800..5952
                     /gene="rpmG"
                     /locus_tag="VQ664_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HET2790096.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            5962..6138
                     /gene="secE"
                     /locus_tag="VQ664_001997"
     CDS             5962..6138
                     /gene="secE"
                     /locus_tag="VQ664_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HET2790097.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            6194..6730
                     /gene="nusG"
                     /locus_tag="VQ664_001998"
     CDS             6194..6730
                     /gene="nusG"
                     /locus_tag="VQ664_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HET2790098.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAEL"
BASE COUNT         2143 a         1198 c         1495 g         2053 t
ORIGIN      
        1 tgaattaatc gctccaatga cttacgaaga gacgatgacg agcgactttt ttgaagtatg
       61 gtttcagaag tttttcttac caacattaac cacaccatcg gttattatta tggataatgt
      121 aagattccat agaatgggga agctagaact cttgtgtgaa gagtttgggc ataaactttt
      181 acctcttcct ccctactcac ctgagtacaa tcctattgag aaaacatggg ttcatatcaa
      241 aaagcacctc aaaaaggtat taccaagttg caataccttt tacgaggctc ttttgtcttg
      301 ttcttgtttc aattgactat atatcacgga tacagttggg aaagaagcta ttaaacattt
      361 ggagagtcct tttgggatga acatgtcaaa tattactata gatgggcaag aaatggatct
      421 gagtcaaacg atgccttctt atgctcaagt agtgagtctt tatgatgata caagtatctc
      481 tgttagtagt aatgagacgg acaaagtgtt ggctggctcc ctctatactg atacaaatga
      541 acagggatta acgattccaa gcagtttact aaaaaattgg aatgaacaga caggaaaaaa
      601 tttgacagct aatgatctta ttggcaaatc agtctcagcc agcattgtag aaagtgctgc
      661 cgaaactagt aagattgctc aatttcaaac gaagattgta cgtgtaatca atgatgaaga
      721 tgacatggag gacagcaaca gtttcatgct gtctcatcaa atggaaacga ttttgaaaga
      781 ggctggattt acgaaagctg tatcttattt tatcttggaa ctcaaagatc catcacagac
      841 aaaagtagta acagaagaat tacagaaaaa taagaagtat actgtgcttt ctcaacagag
      901 agttcttgat attgtgatta tctttattcg tgttattcag ggattattga ttgtgctttc
      961 atcacaagct attgtggtag cagcggttat gattggtatc attatttaca tcaatatcat
     1021 gcagcgttcc aaggaaatag gtgtcatgaa ggcagttggt tatcagaatc gtgatgtcaa
     1081 aggaattttt atttacgagg ctatctggat tgtaggcatc gccttgctgc tggcattttt
     1141 ggttgcacaa ggggtgggaa gtttggcgaa tgcgattgta agtcactttt acccatccat
     1201 cactaaagtt tttgaattaa atcttttatc tgttttagga actctagttt tcgctctatt
     1261 acttggttat gtctcagcct acttcccggc gcgtaagatt agtaaaatgg atcctgtaga
     1321 accgttacgc tatgaatagt aagggattcc ttgatttaca gtcttaaaaa gaaactaaca
     1381 tagaaaaaca atggacatac ttgcaattca actcaaatag ttgtataata ggtttgttga
     1441 aaggtgattt gtagtgattc aagttactct tttcacaata aaaatttcat gattttcata
     1501 aggaggaaat cactaatggt agttaaagtt ggtattaacg gtttcggacg tatcggtcgt
     1561 cttgctttcc gtcgtatcca aaacgtagaa ggtgttgaag ttacacgcat caacgacctt
     1621 acagatccag ttatgcttgc acacttgttg aaatacgaca caactcaagg tcgtttcgac
     1681 ggtactgttg aagttaaaga aggtggattt gaagttaacg gtaaattcat caaagtttct
     1741 gctgaacgtg atccagaaca aatcgactgg gctactgacg gtgtagaaat cgttcttgaa
     1801 gctactggtt tctttgctaa gaaagaagca gctgaaaaac accttaaagg tggagctaaa
     1861 aaagttgtta tcactgctcc tggtggaaac gacgttaaaa cagttgtatt caatactaac
     1921 cacgacgttc ttgacggtac tgaaacagtt atctcaggtg cttcatgtac tacaaactgc
     1981 ttggctccaa tggctaaagc tcttcaagac aactttggtg ttgttgaagg attgatgact
     2041 actatccacg cttacactgg tgaccaaatg atccttgacg gaccacaccg tggtggtgac
     2101 cttcgccgtg ctcgcgctgg tgctgcaaac atcgttccta actcaactgg tgctgcaaaa
     2161 gctatcggtc ttgtaatccc agaattgaat ggtaaacttg atggatctgc acaacgcgtt
     2221 ccaactccaa ctggatcagt tactgaattg gtagcagttc ttgaaaagaa cgttactgtt
     2281 gatgaagtga acgcagctat gaaagcagct tcaaacgaat catacggtta cacagaagat
     2341 ccaatcgtat cttcagatat cgtaggtatg tcttacggtt cattgtttga cgcaactcaa
     2401 actaaagttc ttgacgttga cggtaaacaa ttggttaaag ttgtatcatg gtacgacaac
     2461 gaaatgtcat acactgcaca acttgttcgt actcttgaat acttcgcaaa aattgctaaa
     2521 taattcttga gttgatagaa agcaaggctt tgtggtcttg ctttttatat ggaaaaatgg
     2581 atgacacgat catccattct tttttaattc tttttcaaat gtatttgaaa gggtagtgaa
     2641 agttagcttc tctaaagtaa gtgggtgggt aaaggaaagt cggaaggcat gaagcataag
     2701 ccgacttgtc tttgatttac tattatagag agggtcgccc aggataggaa gattatgatg
     2761 cgaaaggtgc acacgaatct gatgggttcg ccctgtcttt agcttgcaac gagccaagga
     2821 agtcttgttt gagaattgct ttaatctgct tacatacgtt tcagcatatt gcccattttt
     2881 tgcatcaact attctttttc tacgatcatg gcgatcacgt ccaattttgt ctctgaaaac
     2941 aagttctttt ctgttgatat ttccatcaac tagagcccaa tattctctag aaatctcttt
     3001 tttctccaat aagcgattga gaatgggcag gataaaagga tttttggcaa agagaactaa
     3061 gccactggtt tccatgtcca gacgatgaac gacatagcag gtttggccaa cataggtact
     3121 gacatggtta agaagggcaa tttcgtttgg ttgattacca tgcgttttca tcccctctgg
     3181 tttgtttaca ataatcaagt attgatcttg ataaacttcc tgcactaagt ctgggttgcc
     3241 ccaagggatc gtcttttggg gataatcttc ctcgtcaaaa gtcaactggc aaacatctcc
     3301 aggatttacg atttcgttcc agtggacttc ttcttgattt atcaaaatat gtttcttgat
     3361 tctcaaaaaa tgacggattt ttctagggat gaggagttgt tcctcaagta attgctttac
     3421 cgtcatttga ggtagagagg cgggtaatgt aaatgtgaat tgcatacaga tattgtaaca
     3481 aaaaaagccc tatttggata ggaaatagct aaattcttgt cttcctatga tgaagatgat
     3541 aaaataaacg catgaaatta gataaattat ttgagaaatt tctttctctt tttaaaaaag
     3601 aaacaagtga actagaggac tctgattcta ctatcttacg tcgctctcgt agtgatcgaa
     3661 aaaaattagc ccaagtaggt ccgattcgaa aattctggcg tcgttatcat ctaacaaaga
     3721 ttatccttat actaggtttg agtgcaggct tgctagttgg aatctatttg tttgctgtag
     3781 ccaagtcgac caatgtcaat gatttgcaaa atgccttgaa aactcggact cttatttttg
     3841 accgtgaaga aaaagaggct ggtgccttgt ctggtcaaaa gggaacctat gttgagctga
     3901 ctgatatcag taaaaacttg cagaatgctg ttattgcgac agaagaccgt tctttctata
     3961 aaaatgacgg gattaactat ggccgtttct tcttggctat tgtcactgct ggacgttcag
     4021 gtggtggctc taccattacc caacagctgg ctaaaaacgc ctatttatca caggatcaaa
     4081 ctgttgagag aaaagcgaaa gaatttttcc ttgccttaga attaagcaaa aaatatagta
     4141 aggagcaaat tctaaccatg taccttaaca acgcttattt tggaaatggt gtgtggggtg
     4201 tagaagatgc gagtaagaaa tactttggag tttctgcatc agaagtgagt ctggatcaag
     4261 ctgcgactct ggcagggatg ctcaaggggc cggaactgta taatcccttg aattccgtag
     4321 aagattctac taatcggcgc gatactgtct tgcagaatat ggttgcagca ggatatattg
     4381 ataaaaacca agaaaccgaa gctgctgaag ttgatatggc ttcgcaattg cacgataagt
     4441 atgaaggaaa aatctcagat taccgttacc cctcttattt tgatgcggtg gttaatgaag
     4501 ctgtttccaa gtataatcta acagaggaag agattgtcaa taatggctac cgcatttaca
     4561 cagagctgga ccaaaactac caagcaaata tgcagattgt ttatgaaaac acatcgctat
     4621 ttccgagggc agaggatgga acgtttgctc aatcaggaag tgtagctctc gaaccgaaaa
     4681 cagggggagt tcgtggagtt gtcggtcaag ttgctgacaa tgataaaact ggattccgga
     4741 atttcaacta tgcaacccaa tcaaagcgta gtcctggttc tacaattaag cctttagttg
     4801 tttatacgcc agcagttgaa gcaggctggg ctttgaataa gcagttggat aaccatacca
     4861 tgcagtatga cagctataag gttgataact atgcagggat caaaacgagt cgagaagttc
     4921 ctatgtatca agccttggca gaatcgctta atctacctgc tgttgccgct gttaatgatt
     4981 tgggtgtcga caaggctttt gaggcaggcg aaaaattcgg actcaacatg gaaaaggtcg
     5041 accgtgttct tggtgtcgcc ttgggaagcg gtgttgaaac caaccctctt caaatggctc
     5101 aagcatacgc tgcctttgca aatgaaggtt taatgcctga agctcatttt attagtagaa
     5161 ttgaaaatgc tagtggacaa gttattgcga gtcataaaaa ttcacaaaaa cgggtgattg
     5221 ataagtctgt agctgacaag atgaccagta tgatgttggg gactttcacc aacggtaccg
     5281 gtattagttc atcgcctgca gactatatta tggcagggaa aactggaaca actgaagcag
     5341 ttttcaatcc ggagtacaca agtgaccagt gggtaattgc ttatactccg gatgtagtga
     5401 ttagccactg gcttggcttt cctaccactg atgaaaatca ctatctagct ggctctactt
     5461 caaacggtgc agctcatgtc tttagaaaca ttgccaatac cattttacct tatacgccag
     5521 gaagtacctt tacggttgaa aatgcttata agcaaaatgg aattgcacca gccaatacaa
     5581 aaagacaagt acaaaccaat gataatagcc agacagatga taatttgtct gatattcgag
     5641 ggcgtgcgca aagtctagta gatgaggcta gccgggctat ctcagatgcg aagattaagg
     5701 aaaaggctca aacaatatgg gattcgatag tcaatctatt tcgctaagat gcttgtcaaa
     5761 gcctagcttt cttgttataa tggataggat ggaggcgtta tggcactaaa aaaagcaagc
     5821 ctagcttgtg cggtttgtgg ttcgagaaac tattcaatca agatcagcgg aaaccccaag
     5881 cctacacgac tagaagtaaa taaattttgt aagcattgtg gcaagtacac tacacacaga
     5941 gaaacgagat aggagagagc gatgcgtttt attggagata tttttagact tcttaaagac
     6001 acaacgtggc caactcgcaa ggaaagctgg agagattttc gttctatcat ggaatacaca
     6061 gctttctttg tagtaattat ttacattttt gaccagttga ttgtttcagg tttgattcga
     6121 tttattaaca ttttttagaa gattagtgga gttaattaca ctagaaatct tctatattat
     6181 gaaaggaaat atcatggata gttttgataa agggtggttt gttttacaaa cttattctgg
     6241 ttatgaaaat aaggtgaaag aaaatctatt acaacgtgca caaacctaca atatgttgga
     6301 taatattcta cgcgttgaaa ttccaacaca aacagtgcaa gttgaaaaaa atggaaagag
     6361 aaaagaagta gaagaaaatc gctttccagg ttatgttctt gtagaaatgg tcatgacaga
     6421 tgaagcttgg tttgttgttc gaaacacacc aaatgttaca ggatttgtcg gatcacacgg
     6481 gaacagatca aaaccaactc cattattgga acaagaaatt cgtgacattt tggtatctat
     6541 gggacaaact gttcaagaat ttgatttcga tgttgagatt ggtcaaactg tacgtattat
     6601 tgatggtgct tttgcagact acactggtaa gattacagaa attgataata acaaagtgaa
     6661 aatgattatc tctatgtttg gtaatgacac agttgcagaa gtaaacctaa accaaatcgc
     6721 agaattataa ccctgagaga ggctggagcc tctctttttt gtgcagttta ggagctaaag
     6781 ggaacagaat ggagaaaatg taacaaatgt gttttctaat ctgttagact gtatctagaa
     6841 aggggaaaat tatgattaaa gaattgtatg aagaagtcca agggactgt
//
LOCUS       DAVBIC010000077         6743 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.077, whole genome shotgun sequence.
ACCESSION   DAVBIC010000077 DAVBIC010000000
VERSION     DAVBIC010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6743)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6743)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6743
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.077"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            complement(84..1244)
                     /locus_tag="VQ664_001999"
     CDS             complement(84..1244)
                     /locus_tag="VQ664_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET2790099.1"
                     /translation="MKKKFALSFVALASVALLAACVEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVVDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTNMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKDNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEAAEVVKP"
     gene            complement(1345..1593)
                     /locus_tag="VQ664_002000"
     CDS             complement(1345..1593)
                     /locus_tag="VQ664_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HET2790100.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            complement(1672..2262)
                     /gene="clpP"
                     /locus_tag="VQ664_002001"
     CDS             complement(1672..2262)
                     /gene="clpP"
                     /locus_tag="VQ664_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HET2790101.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN"
     gene            complement(2436..3065)
                     /gene="upp"
                     /locus_tag="VQ664_002002"
     CDS             complement(2436..3065)
                     /gene="upp"
                     /locus_tag="VQ664_002002"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HET2790102.1"
                     /translation="MGKIEVINHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETFQPVEYLVKLPEDIDQRQIFVVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(3154..3621)
                     /locus_tag="VQ664_002003"
     CDS             complement(3154..3621)
                     /locus_tag="VQ664_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HET2790103.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            complement(3640..4197)
                     /locus_tag="VQ664_002004"
     CDS             complement(3640..4197)
                     /locus_tag="VQ664_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HET2790104.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            4322..5167
                     /locus_tag="VQ664_002005"
     CDS             4322..5167
                     /locus_tag="VQ664_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HET2790105.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEDGGLLM
                     GYEID"
     gene            5226..6398
                     /locus_tag="VQ664_002006"
     CDS             5226..6398
                     /locus_tag="VQ664_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HET2790106.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDDQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITDLEAAESPLLTDFPHKALQGISLDDVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVKGGEVLSLDVLPQLSEKDLVTFLEENREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFAGEVMDINAHTGGFNITSALCTGWVAGSNPI"
     gene            6413..6658
                     /locus_tag="VQ664_002007"
     CDS             6413..6658
                     /locus_tag="VQ664_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HET2790107.1"
                     /translation="MEQSPKKKKGTTLEHIILLRGVTPNGKNAIPKMSYLVDILTEAD
                     FQQVRTYIQSGNIILESNLALEEIREQVHTLLDFLQN"
     gene            complement(6655..>6743)
                     /locus_tag="VQ664_002008"
     CDS             complement(6655..>6743)
                     /locus_tag="VQ664_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HET2790108.1"
                     /translation="STTYRNHRKRFGLRMNLSAGIINHELGF"
BASE COUNT         1928 a         1405 c         1305 g         2105 t
ORIGIN      
        1 agtttgaaga gattttcgaa gagtattaaa tatcgaaaca gggagtgagt caaaggctca
       61 ttccctattt caacattttt ctattatggt tttacaactt ctgctgcttc aactttacca
      121 ttgttcatgg tcatcatgta agcagttttg actgtgttgt ggtctgcatc gaagcttgtt
      181 tgaccagtta caccttcaaa atcttttgtt ttagcaaggt tatccttgat ttcacctgaa
      241 tttttagcac cttttgctgc gtttgctaca aggtgaactg aatcataagc caaggctgca
      301 aatgttgaag gctcttcatt gtacttagca cggtaagcgt caaggaaggc tttagcttta
      361 gctgaaactt ctacagtagt tgagaagcct gagataaagt agatgtttga tgctttttca
      421 gcagttgctt gttgtacaaa ctcctcaccg ttgaatccat caccaccaac gattggtttg
      481 tcaattccca tgccacgcgc ttggtttaca atcttaccag cctcattata gtaaccagga
      541 acaacgatag catcaaagtc tttccctttc atgtttgtaa gggctgcttg gaagtctgtg
      601 tcacctgcta cgaaagtttc atctgcaacg atttcaccct tgtatgactc gcggaaagat
      661 ttagcaatcc ctttagcata gtcactggca ttgtcagtgt aaagaacaac tttcttagca
      721 tttaattttt cagaaacata gtttgagata atttttcctt ggaagctatc ttggaaagtt
      781 ccaataaaga ggtaatcttg acctttagtc aatccatctt gagtcgcact tggtgagatc
      841 aatggaacac ctgcttttgt agcgttcgct accgcagctg cagtcgcacc agatgtcgca
      901 ggtcctacga ctgctgatac tttagattgg gttacaaggt tagttgtaac tgaagcagcc
      961 tcagctgttt cagacttatt atctttatcg actacttcga tttgttttcc atcgatacca
     1021 cctgcggcat tgatttcatc aacagccaat tgggcacctt tttgttcagc tgttccgtat
     1081 gcagctaaag aacctgattc ttcaaagtta aacccgattt taattgtctt ttcctctact
     1141 gagttaccag cagtgttgac tgctccagac ttcacttcta cacaggctgc aagaagtgct
     1201 acacttgcaa gcgccacaaa cgatagggca aattttttct tcatcttttt gtctccttat
     1261 ttcttaaata gtctgttaag aatataccga attatcagaa aattgtcaat gttttccttg
     1321 aactttttcg atgataacgt tttcctatcg ataaagattg cccacaaagg gtgtttccaa
     1381 ctcttggata tgacaaaccc taactttttt aataaatttt tccttgctca agcgtccgac
     1441 caattgctcc acttcttgag ttggaacata gagttgtaag taacgatgtt tcttggaatg
     1501 ataggtaata tctccataat cctgcagttt tttggcatca cgattatagt aaagatagat
     1561 aatcaagcca gagcgattga ctttttcaaa catgataaat cctctttcta agaaatctct
     1621 ccctattata ccaaaaaaag caaacccagt cgagtttgcc ttctatcatc attagttcaa
     1681 tgaattgttg gccataattt catcaataaa gccatattca agtgtttcct gggcgctcat
     1741 ccagttatca cgttctgcat ctgcatggac tttttccatt gactgacctg aattttcagc
     1801 caagattttt tccaaggtat tacgagtttt gagcaagtgt tctgcagcga tagccatatc
     1861 agtttgttgg gtaccaccac ctgtaccgcc cattggttgg tgaatcatgt attcagcatt
     1921 tggaagcatg aaacgtttgc cttttgctcc acttgatgcg atgactgttc ccatagatgc
     1981 agccattccc ataacaatgg tttggacatc tgccttgata aagttcatgg tatctacgat
     2041 tgccaaacca gctgaaacag aaccacctgg tgtattgaca taaaggtaaa tatcttttgt
     2101 actatcttgg gcatccaaga aaagcagttg ggcaataaca gagttagcca tattgtcttc
     2161 aaccggacct gtcagcataa tgatgcggtc tttgagaaga cgtgagtaaa tatcgtaaga
     2221 acgttctcca cggcttgttt gttcaataac tacaggaatc attcatttct ccttttgagt
     2281 tttaattttg ttggtcaaat gactgaagat aagactatta taatatcttg gtcaaaaaag
     2341 gtcaaatttt tgctctgctt tcattagaca gaaacaaaaa cccaacctcc tttcgtgact
     2401 ggaaatactt ttccaagtca ttcttctttt cgatcttatt ttgtaccgaa caagcggtct
     2461 ccagcatctc caagacctgg aacgatataa ccgtgttcgt tcaaacgttc atccaaggct
     2521 gctgtaaaga tttctacatc tggatgagct tcttgaaggg cttttacacc ctctggagca
     2581 gatacaaggc agacaaattt gatatttgat gcgccacgtt ttttaagaga atcaacagcc
     2641 aagattgctg agccacctgt tgccaacatt gggtctacta caaaaatttg acgttggtca
     2701 atgtcctcag gcaatttcac caagtattca actggttgaa atgtttcttc atcacggtac
     2761 ataccgatgt ggccaacttt agcagctgga accaagctca agagaccatc aaccatcccg
     2821 atacctgcac gcaagattgg gacgatggcc aatttcttac ctgccaattg tttttgaact
     2881 gtttttgtaa ttggtgtttc gatttccaca tcttctagtg gaagatcacg aagtacttca
     2941 taccccatca acattgcaat ctcatctact agctcacgaa aagcttttgt agaagtatct
     3001 gtacgacgca agattgacaa tttgtgttga atcagtgggt gattaataac ttcaattttt
     3061 cccatttttg gaattccttc tttcaattta ttcttcttat tataccaaaa aacgggttaa
     3121 aaatctttct aaaccattta tttttgataa tttttacatt agatcagcct ctttaagagc
     3181 tgtctgtact gtctcaagtg gtaaatgggt caattctgtc cctttttctt gataaaggta
     3241 ttgggcgtag tcgtccattc ggtactggtt gatataaacc acacgcttgc agccgacctg
     3301 aagcaattgt tttgtacagt tgagacaagg aaaatgggtt acataggctg taaagccttt
     3361 gggaacacca cgctcagcac cttgaaggat agcattgacc tcagcgtgaa gggtgcgaac
     3421 acagtggcct tcaatgacca aacattcgtg atcaatacaa tgctcagtcc ctgacaccga
     3481 accattgtaa ccagtggaaa taaccttatt atcttttacc agaatcgcgc ccactttagc
     3541 acgtttacaa gtggaacgat tcgcaattag tagagcttgg gctgcaaaat actcatccca
     3601 ggccagtctt ttttcagtca tctcttttct cctttttctc tattttttaa aaaatggtaa
     3661 acctaaatct gcaatctttt cagctggtac cttcatgcca tccttgatcc attttagaag
     3721 gacagagacg atggctgagc tccagaagga atgaagataa gagctgacac cttttgattt
     3781 cccatggtat ttttctagaa attcctgcat ggcttggaca aagatttttt ccagatggta
     3841 atccaaggcc aattgaatta ctctagcttc ctttctggcc tcccggaaaa ggtgaaccca
     3901 aaccaaataa aggtctgtct ttaaatcgta atgatgcagc tgttccataa tattgtggac
     3961 agttcgttta aagacgctct ctaaaatttc ctctttggag tcataattgc gataaaaggc
     4021 cgcacgcgaa acacctgcac gtttgaccaa ttcagaaata ctaatcttgg tcagttcctt
     4081 tttttccaag agttgcaaga gggctgtttc aatggcttct ctggttaata aattggattc
     4141 ttggtttgat tttctgagat tttcaagaga cttttcagag attctacgtt cagacataac
     4201 attttctttc tacttgtcac aacagacgga tgatgctttt gtttcaaggg ttttcatgat
     4261 ataattgtaa aaaaagacag aacctttgtc aatgtataac tgacaaagat ggagaatttc
     4321 tatgacttgg aagattattg ctgactctgg ttgtgattat cgtcaactgc caacaccagc
     4381 tattaacaca acctttgtaa gtgtcccctt aaccattcaa gtagctgatc aggtctttgt
     4441 tgatgacgcc agtctcgata ttgaccaaat gatggaaacc atgtatgcaa ctgcagaagc
     4501 ttcaaaatcg gcttgtccaa gcccagatga ctatttgcga gcatttgaag gtgccaaaaa
     4561 cattttccta gtaaccatca caggtaccct ttctggcagt cacaatagtg ctcaactagc
     4621 aaagaatatt tatctggaag accatcctga cactaagatt catgtgattg atagtttatc
     4681 tgctggtggt gaagttgacc tactcgtaga aaaattgaat gacttgattg accagggctt
     4741 gtcttttgaa gaagtggttg aagctatcac cgcctatcaa gaaaaaacta agttgctctt
     4801 tgtcctagcc aaagtcgata acttggtgaa gaacggccgt ttgagcaagc ttatcggtac
     4861 ggtcgttggc cttctcaaca ttcgtatggt cggaaaagct agtgaaactg gaactctcga
     4921 attgctacaa aaagcaaggg gatcaaagaa atcagttcaa gctgcctatg atgagttagt
     4981 aaaagctgga tatgctggtg gccgtattgt catggcccaa cgcaataacg aaaaatgttg
     5041 tcaacagctc tcagagcgaa tccgtgaaac cttcccacaa gcggatatta aaattctacc
     5101 aacctctggt ctctgcagtt tctatgcaga agatggcggt ttgctgatgg gctatgaaat
     5161 tgattaattg tattcttgac aagaggtgac catcatctct tgtttttttg tggtacaata
     5221 gagctatgaa acattttgat actattgtca tcggtggggg acctgctggt atgatggcta
     5281 cgatttccag tagcttttat ggacagaaaa ccctcctcat cgaaaaaaat cggaaacttg
     5341 gaaaaaaatt agctgggact ggtgggggac gttgcaatgt gaccaacaat ggtagcttag
     5401 acaacctgct agctggaatt cctggaaacg gacgctttct ttacagtgtt ttctcccagt
     5461 tcgataatca tgacatcatc aactttttta cagaaaatgg tgttaaactt aaggtcgaag
     5521 accacggacg cgtctttcca gccagtgaca agtctcggac tattatcgaa gctttggaaa
     5581 agaaaatcac cgaactaggt ggtcaagttg ctactcaaat agaaatcgtt tctgttaaaa
     5641 aagtagatga ccagtttgtc cttaagtcag cggatcaaac cttcacttgt gagaaactca
     5701 ttgtcacaac aggtggtaag tcttatcctt cgactggttc gactggtttt ggtcacgaga
     5761 ttgctcgcca ttttaagcat accatcaccg atcttgaggc tgctgaaagt cctttattaa
     5821 cagattttcc acataaagcc ttacaaggga tttctttgga cgatgtgacc ctaagttatg
     5881 gtaagcatgt catcactcat gatttactct ttacccactt tggtttgtca ggtcctgctg
     5941 ccctacgcat gtctagcttt gtcaaaggtg gggaggttct ctcactcgat gttttgcctc
     6001 aactttctga gaaggacttg gttacatttc tagaagaaaa tcgggaaaaa tccttgaaaa
     6061 acgctttaaa aaccttgtta ccagaacgct tggccgaatt ttttgtacaa ggatatcctg
     6121 aaaaagtcaa acaactgact gaaaaggaac gagaacaact tgtccagtcc attaaagaac
     6181 ttaaaattcc tgtaactgga aaaatgtccc ttgcaaagtc ctttgttacc aagggtggag
     6241 tcagtctcaa ggaaatcaat cctaaaaccc ttgaaagtaa gctggtacct ggcctccact
     6301 ttgcaggcga agttatggat atcaatgccc acacaggtgg ctttaacatc acttctgccc
     6361 tctgtaccgg ctgggtggcg ggatcaaatc caatctaaat atacattact aaatggaaca
     6421 atcccccaaa aaaaagaaag gaactacttt ggaacatatt atcttgctaa ggggagtcac
     6481 tcctaatgga aaaaatgcta tccctaaaat gtcttatcta gtagatatct tgacagaagc
     6541 tgattttcaa caagttcgaa cttatattca aagtggaaat attattcttg aaagtaactt
     6601 agctctcgaa gaaatacgag aacaggttca tactctatta gacttcctgc aaaactagaa
     6661 tcctagttca tgattgataa taccagcact caaattcatt cgtaatccga agcgtttacg
     6721 atgatttcga taggttgttg aaa
//
LOCUS       DAVBIC010000078         6560 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.078, whole genome shotgun sequence.
ACCESSION   DAVBIC010000078 DAVBIC010000000
VERSION     DAVBIC010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6560)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6560)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6560
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.078"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            1..168
                     /locus_tag="VQ664_002009"
                     /pseudo
     CDS             1..168
                     /locus_tag="VQ664_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            335..535
                     /locus_tag="VQ664_002010"
     CDS             335..535
                     /locus_tag="VQ664_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2790109.1"
                     /translation="MVASASASSTSTQAQEQVDKSELRALSQELDQRLKALATVSDPK
                     IDATKAVLLDAQKAPEDSALTE"
     gene            560..976
                     /locus_tag="VQ664_002011"
     CDS             560..976
                     /locus_tag="VQ664_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2790110.1"
                     /translation="MKAALDSLKDVKANASDSKPAQDKKDAKQGTEDSKDSDKMTETN
                     SVPAGVIVVSLLALLGVIAFWLIRRKKESEIQQLSTELIKVLGQLDAEKADKKVLAKA
                     QNLLQETLDFVKEENGSAETETKLVEELKAILDKLK"
     gene            1207..1914
                     /gene="ccdA2"
                     /locus_tag="VQ664_002012"
     CDS             1207..1914
                     /gene="ccdA2"
                     /locus_tag="VQ664_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HET2790111.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYVMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLALASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            1925..2482
                     /gene="sdbB"
                     /locus_tag="VQ664_002013"
     CDS             1925..2482
                     /gene="sdbB"
                     /locus_tag="VQ664_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HET2790112.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEETKKTQAAQQPKQQTTVQQIA
                     VGKDAPDFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKTVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAEAAFKEMN"
     gene            2603..3994
                     /locus_tag="VQ664_002014"
     CDS             2603..3994
                     /locus_tag="VQ664_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HET2790113.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPSWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIAFPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIMAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILALITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKIPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLIMLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
     gene            4137..5054
                     /gene="adcAII"
                     /locus_tag="VQ664_002015"
     CDS             4137..5054
                     /gene="adcAII"
                     /locus_tag="VQ664_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HET2790114.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDADVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLESDPQNDKTYLENLEENMSILAEELK"
     gene            5062..>6560
                     /locus_tag="VQ664_002016"
     CDS             5062..>6560
                     /locus_tag="VQ664_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HET2790115.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRHQAGQVKKESNRVSYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVDGKYYVYLKDAAHADNIRTKEEIKRQKQER
                     SHNHNSRADNAVAAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGNHFHYIPKSDL
                     SASELAAAQAYWNGKQGSRPSSSSSHNANPAQPRLSENHNLTVTPTYHQNQGENISSL
                     LRELYAKPLSERHVESDGLVFDPAQITYRTVNGVAVPHGDHYHFIPYSQLSPLEEKLA
                     RMIAVKGQNGAVLPGMHYLKPAPKPQVQPSTEKKQTDFAVEQVVRKVGEGYVVEIAGV
                     SHYVFAKDLAKDKIDAIENLLSKKTQETHALVAKKENVAPRDQEFYDKAYNLLTQAHK
                     VLSENKGRTSDFQALDKLAERLNNESSNKVKLVDDLLAFLAPITHPERLG"
BASE COUNT         2015 a         1188 c         1383 g         1974 t
ORIGIN      
        1 tatctggaag aagatatcag agaatttctt tggttgcagg tctaacaaat gaatggtgag
       61 ttaatcgctc caatgactta cgaagagacg atgacgagcg acttttttga agtatggttt
      121 cagaaatttc tcttaccaac attaaccaca ccatcggtta ttatagtaaa atggaataag
      181 aacaggacaa atcgatcagg acagtaaaat cgaattctaa caatgtttta gaagtctata
      241 tgtactattc tagtttcaat ataccataac tgctcctagt caacctgcaa gtcctgtccc
      301 agctccaagc tcagctccga ctcaagatcc tagagtggta gcaagcgctt cggctagctc
      361 aacgagcaca caagctcaag agcaagttga caagtctgaa cttcgtgcct tgagtcaaga
      421 gttagaccaa cgcttgaaag ctttggcaac agtatctgat ccaaaaatcg atgcaaccaa
      481 ggctgtcctc ctagatgctc aaaaagctcc ggaagatagt gccttgacag agtaaggtct
      541 gcatactgca gtagagtctg tgaaggctgc cttggactct ctcaaagatg tgaaagcaaa
      601 tgctagcgac agcaagcctg cacaggacaa gaaggatgca aaacaaggaa cggaagatag
      661 taaggattca gataagatga ctgaaacaaa ctcagttccg gcaggagtga ttgtggtcag
      721 tctacttgcc ctcctaggcg tgattgcctt ctggctgatt cgccgtaaga aagagtcaga
      781 aatccagcaa ttaagcacgg aattgatcaa ggttctagga cagctagatg cagaaaaagc
      841 ggataaaaaa gtccttgcca aagcccaaaa ccttctccaa gaaacccttg atttcgtgaa
      901 agaagaaaat ggctcagcag agacagaaac taaactagta gaggagctta aagcaatcct
      961 tgacaaactc aagtaaaaca tgatttatga aatgtcagac ctaaaagaca ttttcgttca
     1021 caaaagcagt gacgagtaat ccttgtcgtt gctttttggc tattttgggg gataagatcc
     1081 gccttgacta gcaaaagaaa agattggtcc aatagtgccc gatacgattt tgcgtagcag
     1141 aaagcttaca aataaaattg aatatagtaa aataggatta gaattattaa gaaagttggt
     1201 tctttattgg aaacgatagt atttttaatc tctgtttttc tagcaggtgt tttatccttt
     1261 ttttctcctt gtatttttcc tcttctgcca gtctatgctg ggattttatt ggatgatcaa
     1321 gaaagtgcaa aaagcttttc tttgtttggg agaaaggttc tctggtcagg cttgattcga
     1381 acactttgct ttatcgctgg tatctctctc attttcttta ttctaggctt tggtgctggt
     1441 tactttggtc atattctcta tgcaaattgg tttcgatatg tcatgggagc tattattatc
     1501 attttgggtc ttcaccagat ggaaattttt catttgaaga aattagaagt tcaaaaaagt
     1561 tttaccttta aaaaatcaga ttctaatcgt tattggtcag cttttttact tggtattacc
     1621 tttagctttg gttggacacc ttgtattggt ccagttttaa gttctgtttt agcacttgcg
     1681 gcttctggag gcaatggtgc ttggcaagga gcgatttata ctctcattta cactctgggc
     1741 atggcccttc ctttcttggt cttggcacta gcttcaggtc tagtcatgcc atattttagt
     1801 aaaatcaagc gtcatatgat gctactaaag aaaattggtg gtttcctcat tgttttaatg
     1861 ggaattttgt tactattagg acaagtaaat gttctagctg gaatttttga ataaaggagg
     1921 acaaatgaaa aaagtaatgt ttgctggctt aagtctcttg tcattagttg tattgatggc
     1981 ctgtggtgag gaagaaacta aaaagactca agcagcacaa cagccaaaac aacaaacgac
     2041 tgtacaacaa attgctgttg gaaaagatgc tccagacttc acattgcaat ccatggatgg
     2101 caaagaagtt aagttatctg attttaaggg taaaaaggtt tacttgaagt tttgggcttc
     2161 atggtgtggt ccatgcaaga aaagtatgcc agagttgatg gaactagcgg cgaaaccaga
     2221 tcgtgatttc gaaattctta ctgtcattgc accaggaatt caaggtgaaa aaactgttga
     2281 gcaattccca caatggttcc aggaacaagg atataaggat atcccagttc tttatgatac
     2341 caaagcaacc accttccaag cttatcaaat tcgaagcatt cctacagaat atttaattga
     2401 tagccaagga aagattggaa agattcaatt tggtgctatc agtaatgcgg atgcagaagc
     2461 agcatttaaa gaaatgaact agaatcgata aaatctgatt acaagatgta gtcagatttt
     2521 tttagaaaaa cattttataa atattcacat atctcctata tttatggtaa aatagaatta
     2581 tcagtttatt ttggagtcaa agatgaatat atttagaaca aagaatgtta gtttagataa
     2641 aacagagatg cataggcatt tgaagttatg ggatttgatt ttgctgggta tcggagccat
     2701 ggtagggaca ggcgtcttta caatcacagg tactgcagct gcaacacttg ctggcccagc
     2761 cctagtgatt tcaatcgtta tttctgcctt gtgtgtggga ttatcagccc tcttttttgc
     2821 agaatttgcc tcgcgagtac ccgctacagg aggtgcctat agttacctct atgctatctt
     2881 aggagaattc ccttcctggt tggctggttg gttaaccatg atggagttca tgacagccat
     2941 atcaggcgta gcttcgggtt gggcagctta ttttaaaggc ttgctctctc aatacgggat
     3001 agcctttcct caggctttaa atggtacctt taatcctcaa gcagggacat ttgttgattt
     3061 attgcctatt cttgtcttgg tcttggtgac ttcgcttgtt ttactaaatg ccaaggcagc
     3121 cttacgcttt aattcgattc tagttatttt gaaattttcc gctttagctc tctttgtttt
     3181 agtaggaatt tggaatatta agtttgataa ttggagcaat tttgctcctt acggttttgg
     3241 acaaatctat ggagctagca ctggtattat ggctggtgcg tccttgatgt tcttcggttt
     3301 tttgggattt gaatccatct ctatggctgt agatgaagtc aagactcctc aaaaaaatat
     3361 tcctagaggg attgtcttat cgctttctat cgtaaccatt ctctatgcct tggtgaccct
     3421 tgttttgact ggtgtggttc actatagtca tttaaatgtc gatgatgccg ttgcctttgc
     3481 ccttcgtagt gttgggatta gttgggcagc caactatgtg tcattagtgg ctatcttggc
     3541 cttgattaca gtttgtattt cgatgaccta tgccctatcg cgtatgattt acagtttagc
     3601 acgtgacggc ttagtgcctg ctgcctttaa ggaactgacg aagactagca agataccaaa
     3661 gaatgctact atcttgacag gtctagcttc agcagtagca gcaggaatgt tcccactagc
     3721 cagtattgca gcctttttaa atatttgtac cttagcctac ttgatcatgc tggcttatgg
     3781 tctgattcgc ttacggaaag aaaaaggaat gcccaaagct ggggaattta aaacaccatt
     3841 ggtacctctg ttaccaattt tatcgatcat catttgttta tccttcatgt tacagtataa
     3901 tatgaacacc tggattgctt tcctagttgc gttgttagta ggaagtatta tttacttcac
     3961 ttatggctat aagcattcta ccatagaaga ataaagtgaa agtctattga gttgttgaca
     4021 ctcagtagat ttttatatgt gaaagaaatt tcaaattttt tctaaaaata tcttgacaga
     4081 ttaaattttc aggagtagaa tatttactag ttaattaaat ggttaaggag ttgttcatga
     4141 agaaacaaaa tttattttta gtcctgttaa gtgtctttct tttgtgtttg ggggcttgtg
     4201 gtcaaaagga aagtcagaca ggaaagggga tgaaaattgt gaccagtttt tatcctatct
     4261 acgctatggt taaggaagta tctggtgact tgaatgatgt tcggatgatt cagtcaagta
     4321 gtgggattca ctcctttgaa ccttcggcaa atgatatcgc agccatctat gatgcagatg
     4381 tctttgttta ccattctcat acactcgaat cttgggcagg aagtctggat ccaaatctaa
     4441 aaaaatccaa agtgaaggtc ttagaggctt ctgagggaat gaccttggaa cgtgtccctg
     4501 gactagagga tgtggaagca ggggatggag ttgatgaaaa aacgctctat gaccctcaca
     4561 catggctaga tcctgaaaaa gctggagaag aagcccaaat tatcgctgat aaactttcag
     4621 aggtggatag tgagcataaa gagacttatc aaaaaaatgc gcaagccttt atcaaaaaag
     4681 ctcaggaatt gactaagaaa ttccaaccaa aatttgaaaa agcgactcag aaaacatttg
     4741 taacacaaca tacagccttt tcttatctag cgaagagatt tgggcttaat caacttggta
     4801 ttgcaggtat ctctcctgaa caagaaccaa gtccacgaca actaacagaa attcaggaat
     4861 ttgttaagac ctataaggtt aaaacgattt ttacagaaag taacgcttct tcaaaagtag
     4921 ctgaaactct tgtcaaatca acaggtgtgg gtcttaaaac tctgaatcct ttagagtcag
     4981 acccacaaaa tgacaagacc tatttagaaa atcttgaaga aaatatgagt attctagcag
     5041 aagaattaaa gtgaggaaag aatgaaaatc aataaaaaat atctagcagg ttcagtggca
     5101 gtccttgccc taagtgtttg ttcctatgaa cttggtcgtc accaagctgg tcaggttaag
     5161 aaagagtcta atcgagtttc ttatatagat ggtgatcagg ctggtcaaaa ggcagaaaat
     5221 ttgacaccag atgaagtcag taagagagag gggatcaacg ccgaacaaat tgttatcaag
     5281 attacggatc aaggttatgt gacctctcat ggagaccatt atcattacta taatggcaag
     5341 gttccttatg atgccatcat cagtgaagaa cttctcatga aagatccgaa ttatcagttg
     5401 aaggattcag acattgtcaa tgaaatcaag ggtggctatg tgattaaggt agacggaaaa
     5461 tactatgttt accttaaaga tgcagcccat gcggacaata ttcggacaaa agaagagatt
     5521 aaacgtcaga agcaggaacg cagtcataat cacaactcaa gagcagataa tgctgttgct
     5581 gcagccagag cccaaggacg ttatacaacg gatgatgggt atatcttcaa tgcatctgat
     5641 atcattgagg acacgggtga tgcttatatt gtccctcacg gcaatcactt ccactatatt
     5701 cctaagagtg atttgtctgc cagtgaatta gctgctgccc aagcctattg gaatgggaag
     5761 cagggatctc gtccttcttc aagttctagt cataatgcaa atccagctca accaagattg
     5821 tcagagaacc acaatctgac tgtcactcca acttatcatc aaaatcaagg ggaaaacatt
     5881 tcaagccttt tacgtgaatt gtatgctaaa cccttatcag aacgccatgt agaatctgat
     5941 ggcctagtat ttgatccggc acaaataaca tatcgtacag tcaatggtgt tgctgtaccg
     6001 cacggagacc attatcactt tattccttat tcacaactgt cacctttgga agaaaaattg
     6061 gctcgtatga ttgctgttaa gggacaaaat ggtgcagtct tgccaggaat gcattatttg
     6121 aaaccagcac caaaaccgca agttcaacca tcaactgaga aaaaacaaac tgattttgca
     6181 gtagaacagg ttgttagaaa agttggagaa ggctatgttg tggaaattgc tggtgtcagt
     6241 cactatgttt ttgctaaaga cttggctaag gataagattg atgctattga aaatctcttg
     6301 tctaagaaaa ctcaagagac acatgctcta gttgctaaaa aagaaaatgt cgctcctcgt
     6361 gaccaagaat tttatgataa agcttacaat ctgttaaccc aggctcataa agtcttgtct
     6421 gaaaataaag gtcgtacttc tgatttccaa gccttagaca aattagcaga acgcttgaat
     6481 aatgaatctt ctaataaagt aaaattggta gatgatttat tggcattcct agcaccaatt
     6541 acccacccag aacgccttgg
//
LOCUS       DAVBIC010000079         6186 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.079, whole genome shotgun sequence.
ACCESSION   DAVBIC010000079 DAVBIC010000000
VERSION     DAVBIC010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6186)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6186)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6186
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.079"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            complement(119..751)
                     /locus_tag="VQ664_002017"
     CDS             complement(119..751)
                     /locus_tag="VQ664_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET2790116.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAMQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKNTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     GDTKFDMLGARETGIQKLAVTWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
     gene            complement(773..1645)
                     /gene="sdaAA"
                     /locus_tag="VQ664_002018"
     CDS             complement(773..1645)
                     /gene="sdaAA"
                     /locus_tag="VQ664_002018"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HET2790117.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIKNEKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            complement(1654..2325)
                     /gene="sdaAB"
                     /locus_tag="VQ664_002019"
     CDS             complement(1654..2325)
                     /gene="sdaAB"
                     /locus_tag="VQ664_002019"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HET2790118.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            2567..3139
                     /locus_tag="VQ664_002020"
     CDS             2567..3139
                     /locus_tag="VQ664_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HET2790119.1"
                     /translation="MKSITKKIKATLAGVAALFAVFSPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVDQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNGDYSAE
                     NQERVADAYVAGRYGSWTAAKNFWLNNGWY"
     gene            complement(3191..4054)
                     /locus_tag="VQ664_002021"
     CDS             complement(3191..4054)
                     /locus_tag="VQ664_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001268160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2790120.1"
                     /translation="MRYDFGKVYKEIRESKGLTQEEVCGGVLSRTSLSKIESGKTTPK
                     YENMEFLLRQINMSFEEFEYICQLYQPSQRTEIMQTYLNMRSIIGTSDLVNLFQKCQD
                     YLKTHHDLPIEEIRDMLEVVIYLRQHGAGELSKHAEQVVKKLWKKIEKQDTWYESDLK
                     ILNTILFSFPIEYLHLITGKILQRLEVYKNYQHLYDLRMTILLNLSTLYLYNQDKNMC
                     KQICYTLLEDAKNKKSYDRLAICYVRIGICTDDSKLIQKGFSLLELTEETSMLSHLKK
                     EVEIYYQAKER"
     gene            4520..4858
                     /locus_tag="VQ664_002022"
     CDS             4520..4858
                     /locus_tag="VQ664_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C39"
                     /protein_id="HET2790121.1"
                     /translation="MLKKYPCTMQHDQSDCAAAVVSTVLLSYKKELSIMKIREIIGTD
                     MYGTTVSGIVSGLNKLNFTVKAVRVALEDLTPKLTFPAILQVKNDLGQNHFVVLHSIK
                     EKINGTRITK"
     gene            4836..5195
                     /locus_tag="VQ664_002023"
     CDS             4836..5195
                     /locus_tag="VQ664_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2790122.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGAIYIPRWAITGAITGAAYAAL
                     AAAGGGGLQLVLASYGLRSALVAGIVKGLGVLGIHIGNAFANTVIRSIASAGIGAGAD
                     WILPILLMAGMGDVIIN"
     gene            5214..5426
                     /locus_tag="VQ664_002024"
     CDS             5214..5426
                     /locus_tag="VQ664_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000989850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2790123.1"
                     /translation="MMVVLISVIVAFLYHKITEYVNNRKIDIVIFLSLLISHFIWNYY
                     FLPIEILIAISGANLLLSFLKKLQIK"
     gene            5841..5909
                     /locus_tag="VQ664_002025"
                     /pseudo
     CDS             5841..5909
                     /locus_tag="VQ664_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
     gene            5889..>6186
                     /locus_tag="VQ664_002026"
     CDS             5889..>6186
                     /locus_tag="VQ664_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HET2790124.1"
                     /translation="MMYLDGGGVGCNWWNKRDNIAAAAVSGGMSVYQTYAIKKLIANR
                     GMMSRVVRSAITRYIGGVSMATITNALNIAATVAEVFSLGGAIAYGLDIVDGKFD"
BASE COUNT         1901 a         1050 c         1310 g         1925 t
ORIGIN      
        1 atctacaacc ttaaaacagt gttttgagca gcccgcagct agtttcctag tttgctcttt
       61 gattttcatt gagtattact tcattttctt ctgaaataga gttgtcgccc agtctatgct
      121 attgaaaata cgccaaaact tctaagggtt tgtgagcgat ataatcaggt tgatagttta
      181 gtagatctgc ttgctctcca aatccccaag tgacggccaa tttctgaata cctgtttctc
      241 gagctcccag catatcaaac ttggtatctc cgatgatgat ggcttgttct ggtgctagtt
      301 gatgtgtctg taaggcttgg tgaatgacat ctgccttatg gggtgcttca gggctagaac
      361 cataaatacc atcaaagaaa tgatggattt ccaagttttt ggccatgtct tgagcagtag
      421 atgtattctt tgtcgtggtg atgtagagtg gataactgct cgataactcc tcaagcaagt
      481 ctataatctg aggaaagagt tgagcttcat agatgccttt tgccttatag taagaacgat
      541 atatctgcat ggcttcagaa atttggtctt tggacaggca ggtcgcaaaa ctactttcga
      601 gaggtggtcc cataaaacca cgaatagttt tggcatcagg gctaggcacc cccagctctt
      661 taaaggtata ggtaaaggca ttgtgaatcc cgatagaact atcaacgagg gttccatcca
      721 aatcgaaaaa aatcgctgtg atagaggtca tggtttctcc tatttgataa gcttattctc
      781 cgaaaatctc tttttggagg cgacgaccag taggggtggt agcgagtcca ccttcagctg
      841 tttcacgaaa ggcagttggc atgcttgctc ctacttggta catggcatcg atcacttcat
      901 ccacagggat tttagattcg atacctgcca aggccatgtc tgctgcgatg aaagcaaagc
      961 tagctcccat ggcattacgt ttgacacagg gaacttcgac caaacctgca acagggtcac
     1021 agatgaggcc tagcatattt ttaatgacaa aggcaatagc ttgactggcc tgataaggtg
     1081 ttccacctgc agccagagtc aaggcggcag cactcatagc agaggctgaa ccaacttcag
     1141 cttgacaccc accctcagca cctgagatgg aggcattgtt tgcgatgact agtccaaagg
     1201 caccagcagc aaagaggaaa tccaattgtt gctcgtggct gaggtctaat ttttcaatag
     1261 cagcagtgag aacggaaggg agacaaccgg cacttcctgc ggtaggagta gcgcagacca
     1321 agcccatttt agcattgtgt tcattgactg cgatagcatt tcgggcagca gagagaatcg
     1381 tgtaatctga taaagttttt tcgtttttga tgtagtgatc caatttggca gcatctccac
     1441 ctgtcaggcc actacgagat ttattttcat tgaggccaag ttggacagag gctttcataa
     1501 cttccagatt gcgttccatg agaaggaaga cttcttcacg ttcgcgaccg gtcaattcaa
     1561 actctgttgt aatcatgagt tctgcgacat ttccttgaaa gtccagatct gcttgctcga
     1621 ccaattcttt gatagaataa aacatgcttc ctcctattta aagaaattga cattgtggag
     1681 atgagggatt tttcgaattt cttcgatagc ctcatcacag ttgcgactgt caacttcgat
     1741 aatcataatg gctttttcac cagctttttc acgagtgaca ttcatctggg cgatattgat
     1801 accatagcgg gaaagcgcct ctgtaacaag ggcaatcata cctggaatat cttgatgaac
     1861 gatgatgata gtcggtgtat tcatattgag agagacggca aaaccattga gttcggttac
     1921 ctgaatattt cctccaccga tagaaatacc agtcacgctg atggtcttgt gggcattttt
     1981 aacagtaatt ttagtggtgt tagggtgagg ggcattgctg tctttctgaa tggtccagac
     2041 aatcttgata ccacgcttgt gggcaatttc cagactattt ggaatttcag gatcatctgt
     2101 atccattcct aaaatacctg caacaagggc taggtctgtt ccgtgaccac gataggtctt
     2161 ggcaaatgag ttaaaaagtt ggaattcaac ttctgtcgga gtatcatcaa aaatggaaga
     2221 gacaatcttc ccaatacgaa cagcaccagc ggtatggcta ctagatgggc caatcataac
     2281 tggtccgatg atatcaaaga cagattgaaa acgaagtgat ttcatcagtt tccccttata
     2341 aaaattctta tctctattat atcaaagaat gaggggcttg gctttaattg tggatgaaaa
     2401 cctttctaat acctcaaata gcataaaaat agtatctttt atgacaaaaa acaccttatt
     2461 tagggaaata aaaaataatt ttgtaatatt tctacataaa agtgtcaaga aacagtaata
     2521 tttaaagggt atgatagaac tatagaaaga aggagaattt tcgaatatga aatcaataac
     2581 taaaaagatt aaagcaactc ttgcaggagt agctgccttg tttgcagtat tttctccatc
     2641 atttgtatct gctcaagaat catcaactta cactgttaaa gaaggtgata cactttcaga
     2701 aatcgctgaa actcacaaca caacagttga aaaattggca gaaaacaacc acattgataa
     2761 cattcatttg atttatgttg atcaagagtt ggttatcgat ggccctgtag cgcctgttgc
     2821 aacaccagcg ccagctactt atgcggcacc agccgctcaa gatgaaactg tttcagctcc
     2881 agtagtaagt gaaacagttg tttcaactgt aagcggatct gaagcagaag ccaaagaatg
     2941 gatcgctcaa aaagaatcag gtggtagcta tacagctaca aatggacgtt atatcggacg
     3001 ttaccaatta acagattcat acctgaacgg tgactactca gctgaaaacc aagaacgtgt
     3061 agcagatgcc tacgttgcag gacgttacgg ttcatggact gctgctaaaa acttctggct
     3121 taacaatggc tggtattaag aactaacgaa caaataatat gtaaagagtc gaggaaatcc
     3181 ctcggctttt ttatctttcc ttcgcttggt aatagatctc tacttctttt ttgagatgag
     3241 acagcataga agtttcctcg gttagctcca gaagggagaa ccctttttgg ataagtttag
     3301 aatcgtctgt acaaatccca atacggacat agcagatagc cagcctatcg tagcttttct
     3361 tattcttggc gtcctccagt aaagtgtagc agatttgctt acacatgttt ttatcttgat
     3421 tgtatagata gagtgtggaa aggtttaata gaattgtcat tcgcaagtca tataaatgtt
     3481 gatagttttt atagacttct aggcgttgca atatttttcc agtgatgaga tggaggtatt
     3541 caatgggaaa actgaaaaga atggtattga ggatttttag atcactctca taccatgtat
     3601 cttgtttttc aatttttttc caaagttttt tgacaacctg ttctgcgtgt tttgatagtt
     3661 cccctgcccc gtgttgacgg agataaataa caacttcaag catatctctg atttcttcta
     3721 tagggagatc gtggtgggtc ttgaggtagt cttggcattt ttgaaataaa ttgacaagat
     3781 cgctggtccc gataatggaa cgcatattga gataggtttg cataatctct gtgcgttgac
     3841 ttggttgata aagttgacag atatattcaa actcttcaaa actcatattg atttgacgga
     3901 gaagaaattc catattttca tattttgggg ttgtcttgcc actttcgatt tttgataagc
     3961 tggttcttga gagaacaccc ccacagacct cttcttgggt cagccccttt gactcacgta
     4021 tttctttata gacctttccg aaatcataac gcatgatttt ctcctttctg tgaaaaaagt
     4081 taacaaacaa taaaattttg ttaaaaatat tgtatcatag caatgtaaaa agtaaaaaag
     4141 aaagtcgaaa taaatttgtg aaaaaagtta acgtaatttt aaaatgagct taataagagg
     4201 tatgatgtag gtagaaaata aagataggag aaaaagtatg aataaaaaaa tattttgtat
     4261 tctagtatgt attatatcat tgattagtct ggccataatc tttccatggg gctggtcgat
     4321 ataatgtaag ggagcttgag ttgttaaagg aggcttagtc cttggacaaa aatctgctgt
     4381 actacaatgc ttggaaagat atcaagaaca aagaatgata cgattgaaaa taaactgatt
     4441 caagaactac tgggcagtga ttgaggtttg ggtgacatca aagaaaagtt agattaattc
     4501 taaagaattg agtatttcta tgttaaaaaa atatccttgt acgatgcaac atgatcagtc
     4561 agattgtgct gcggcagttg tttcaacagt tcttttatct tacaaaaagg aactatcaat
     4621 catgaagatt cgggaaatta ttggtacaga catgtatgga acgactgtca gtggtattgt
     4681 ttcaggtctg aataagttga attttacagt aaaagctgtt cgagtagcac tggaagattt
     4741 gactccaaaa ttaacatttc ctgcgattct tcaagttaag aatgatttag gtcaaaatca
     4801 ttttgtggta ttacatagta taaaggagaa aataaatgga actcgtatta ccaaataatt
     4861 atgttgtgat tgatgaagaa gagatgatgt accttgatgg gggggctata tatataccca
     4921 ggtgggcaat tacaggagcc attactggtg cagcatatgc agcattagca gcagcaggag
     4981 gtggaggcct tcaactagtt cttgcatctt atggattacg ctccgcactg gtagctggga
     5041 ttgttaaagg tttaggagta ttaggaattc atattggaaa tgcttttgca aatactgtta
     5101 ttagaagtat tgcatctgct ggaattggtg ctggagctga ttggatttta ccaatattat
     5161 tgatggctgg gatgggcgac gtgataatca attgagaata ggataatagt attatgatgg
     5221 ttgttttaat ttcagttatt gttgcattcc tgtaccataa aattacagag tatgtcaaca
     5281 acaggaaaat tgatattgtt atttttctat cattgctgat ttctcatttt atttggaatt
     5341 actatttttt accaattgaa atattgatag caatcagtgg agcaaattta ttattaagtt
     5401 ttttaaaaaa attacagatt aaataatatt attccatatg acatatcaac taggtcatta
     5461 gattttattg aagatataaa ttaaaaacga ggttgggaaa aaactcaatt tgaaagtgaa
     5521 attgagtaaa tttttctatt atataacgca tattatcaag atttttgaac acctgataat
     5581 atgcactttt cttattttaa agattttttg cctttcttca tttcttgaat gaattggaga
     5641 gatgacttta tttaggtgtt tgacattact atagatagga tttagcagta ctaatatgaa
     5701 ctcatattat aggtgcagac ttaaattttg gaagcaagct aaaggatatc ttatctaggt
     5761 aactaagtgc tataaacaaa gtcaacgatc acttgttagg aaacgatcct aactatgctt
     5821 aataaaaaag gagaaaataa atggaactcg tattaccaaa taattatgtt gttcttgagc
     5881 aagaagagat gatgtatctt gatgggggtg gtgttggttg taactggtgg aacaaacgtg
     5941 ataatattgc tgcagctgca gtttctggag ggatgtcagt ataccagaca tatgccatta
     6001 aaaagttaat tgctaatcgt ggtatgatga gccgagtcgt tagaagtgct ataacaagat
     6061 atattggtgg agttagtatg gcaactatta ctaatgctct taatattgcg gctactgttg
     6121 ctgaagtttt ctcattagga ggagccattg catatggttt agatatcgta gacggtaaat
     6181 ttgatg
//
LOCUS       DAVBIC010000080         4613 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.080, whole genome shotgun sequence.
ACCESSION   DAVBIC010000080 DAVBIC010000000
VERSION     DAVBIC010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4613)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4613)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4613
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.080"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            complement(374..1570)
                     /gene="tuf"
                     /locus_tag="VQ664_002027"
     CDS             complement(374..1570)
                     /gene="tuf"
                     /locus_tag="VQ664_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HET2790125.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            complement(2481..3350)
                     /locus_tag="VQ664_002028"
     CDS             complement(2481..3350)
                     /locus_tag="VQ664_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HET2790126.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTEKPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKAIEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIAA
                     AIAAVAVFKFLYL"
     gene            complement(3573..4253)
                     /locus_tag="VQ664_002029"
     CDS             complement(3573..4253)
                     /locus_tag="VQ664_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HET2790127.1"
                     /translation="MVPKTATSTETKTITRIIHYVDKVTNQNVKEDVVQPVTLSRTKT
                     ENKVTGVVTYGEWTTGNWDEVISGKIDKYKDPDIPTVESQEVTSDSSDKEITVRYDRL
                     STPDKPTPEKPEIPSPQEPGTPGEPTPEKPIPQPNPEHPSVPTPNPELPNQETPTPDK
                     PTPEPGTPKAETPVNPDPEVPTYETGKREELPNTGTEANATLASAGIMTLLAGLGLGF
                     FKKKEDEK"
     gene            complement(4211..>4613)
                     /locus_tag="VQ664_002030"
     CDS             complement(4211..>4613)
                     /locus_tag="VQ664_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HET2790128.1"
                     /translation="FKEADTNSASLTGNIVSEGRTVTLVYRESEAPTTATVTANYYKE
                     GSQEKLAESVIKADLAIGSEYTTESKTIEGKTTTEDKEDRVITRKTTYTLVATPANAY
                     QKTVQQLTITTVRMLRKQWFPKQQPLLRRRL"
BASE COUNT         1293 a          931 c          903 g         1486 t
ORIGIN      
        1 tataatgctt tttgatttta gtctagtatt atactcttcg aaaatctctt caaaccgcgt
       61 cagcttcgcc ttgtcgtata gatgttactg acttcgtcag ttctatctac aacctaaaaa
      121 cagtgttttg agcagtctgt agctaacttt ctatagtaaa atgaaataag aacaagacaa
      181 atcgatcagg acagtcaaat cgatttctaa caatgtttta gaagtaaatg tgtactattc
      241 tagtttcaat atattatagt ttgctctttg attttcattg agtattagtt caatatctaa
      301 aaaaagaacc ttgccaagca agattctttt agtgtctgac ttaaataatt gttcttctgg
      361 gaactaaatc gaattaagct tcgatttctg taaccatacc tgaaccaaca gtacgtccac
      421 cctcacggat agagaatgta gtaccttgtt ctacggcgat tgggtgaatc aactcaacgt
      481 cgattgtcac gttatcacca ggcattacca tttcagtacc tgctggaagt tcgattgaac
      541 ctgtaacgtc agtagtacgg aagtagaatt gtggacggta gttgttgaag aatggagtgt
      601 gacgtccacc ttcttcttta gtaaggatgt agacttcacc tttgaattta gtgtgtgggt
      661 tgattgaacc tggtttagcg ataacttgtc cacgttcgat ttcatcacgt tgaacaccac
      721 gaagaaggac acctacgtta tctccagcaa gaccttcgtc aagttgttta cggaacattt
      781 caacaccagt aacaactgct ttttgagttt cttctttgat accaacgatt tcgatttcgt
      841 cgttgacttt aacgatacca cggtcgatac gtcctgaagc aactgtacca cgtccagtga
      901 ttgagaatac gtcctcgact ggaagaagca atggtttgtc agtgtcacgt tctggttctg
      961 ggatatactc atcaactgtg ttcatcaatt ccataacgat gtcttcgtat ttagagtcac
     1021 cttcaagagc tttaagtgct gaaccttgga taactggaag atcgtcacct gggaagtcgt
     1081 attctgacaa taggtcacgg atttccattt caaccaattc aagcaattct tcgtcgtcaa
     1141 ccaagtcaac tttgttcatg aagacgataa ggtgtttaac accaacctga cgtgaaagaa
     1201 ggatgtgctc acgagtttgt ggcattggtc cgtcagttga agctactaca aggatagctc
     1261 cgtccatttg agcagcacca gtgatcatgt ttttaacgta gtccgcgtgt cctggagcgt
     1321 cgatgtgagc gtagtgacgt ttttcagttt cgtactcaac gtgcgcagtg ttgatagtga
     1381 taccgcgttc gcgttcttct ggagcagcat cgatagacgc atagtcttta ggttggttaa
     1441 ctgatgaagg caagcgacgt gccaaaacag ttgtgatagc tgcagttagg gtagttttac
     1501 cgtggtcaac gtgtccgata gtaccaatgt taacgtgtgg tttactacga tcgtattttt
     1561 cttttgccat ttgagtaaaa gcctccaata aaatatattt tatagataga cagtaggcaa
     1621 tacagtctaa ctttccttac tattttatca aatttcagct aaattgcaag tgttttacaa
     1681 cgtttttgtg aattattctt ggtaaaaatt taactaatta atagaaagta ctaaatagac
     1741 ttatccttca aggagttttc agcattatcc atccactcac ttgctgaaaa tgtaaacagt
     1801 ctctggttta tatagtaaaa tgaaacaaga atagagcaaa tcgatcagga cagtcaaatc
     1861 gatttctaac aatgttttag aagtagatgt gtactattct agtttcaatc tactatacaa
     1921 cctcaaaact gtgttttgaa caacctgcgg ctagcttctt agtttgccct ttgattttca
     1981 ttgagtataa aattgcagat aaaacgataa caatcatagg actcagcaga gtcaatgtag
     2041 gtcgaagaat agccccccta atcgcttatt ttatagcaaa atgaaataga aactgaacat
     2101 tttgttgagg aaggtaaatc aattcctcac aatgtttgag aaagaaggga ggactattcc
     2161 aacttcaacc cactataaag cagacttaca agatagggaa cccatctccg ataatatata
     2221 gtagaatgaa aactgcacaa tttgattgga gaattcaaac caatttctaa caatgtttta
     2281 gaaacaaggg tctattattt caactgcaac ctactatagc ccattgaagc tggaatagcc
     2341 cactgagact tctaaaccac tgctggagag gagtttgttt agagtttctt tcatttccct
     2401 aaaaaatcaa aaagagagaa ccagtctgat cctctcttac ttatagatgg tgctcactca
     2461 aatgttaaag gagctatttc ttagagataa aggaatttga atacagctac tgccgcaatt
     2521 gctgctgcga taggtgctac tactggtacc caagaatacc accattttga atcgccttta
     2581 tgctcaccaa gaactgattt tggaaggaaa gcatgaagga gacgtggtcc caagtcacgg
     2641 gctgggttca aggcaggtcc tgtaggtcct ccaagtgatg ttaccaaagc cataacgagg
     2701 aatccaagtg ccaagtgagc cacagaaagt cctgaagcag tgtgtggagc cacctgtgct
     2761 ttaatagcca agtcagaaaa atcaactgtt tgtcctgctt ctattgcctt ttgtttcatg
     2821 aattgaagca cttcagcacc aaagaagttt ttagtcaaac caagagctgc aaagaacaaa
     2881 acaaatgaac caacaaactc attaatcaaa ccattgacag ttgctgcata gcgactttct
     2941 tttgtaccat ggtcaatact tgaaatagtt gagaaagttc ccaagatgtt atttggtttt
     3001 tcagttttca agtagaatgg acggtatgtt gccacaacta aggcttggcc aaagatagcc
     3061 cccaagactt gcgcgataat gtaaggtacc acttgtgccc aagggaaaag accgctaact
     3121 gcaagcccta gagtgaaagc agggttgatg tgattcccag atacgttacc aaacatcaag
     3181 gctgggatca taacccccat accataacca acagcgatga cgatccagcc actttggtga
     3241 cctttcgtac ctttaagttc aacgttggca actgcaccat tcccaagaat gatcaaaatg
     3301 gcagttccca aaaattcagt ggcatacttc agtgcccatg tgaaatccat ttgctagatt
     3361 ctccttaaaa ttttttagat attccttatt ttatcaattt ttaccctatt tagcaactga
     3421 tttctggaaa tatttttaaa aaaataggat tcatagtttc ccagttcaac gtacttgtaa
     3481 gcgtttttat tcttcacgaa agacctcatt ctcaaaacca ggaaaaagcc cacatctgtg
     3541 atcttttcct ggttcctaga ttctaaaatc tattattttt catcttcttt tttcttgaag
     3601 aatcctaatc ctagaccagc taacaaggtc atgataccag cactagccaa ggtagcatta
     3661 gcttctgtac ctgtgtttgg caattcctct ctcttacctg tctcataagt cggaacttct
     3721 gggtctggat tcactggagt ttcagctttt ggagtacctg gttctggagt tggtttatct
     3781 ggtgttggag tctcttgatt tggtagttct gggtttggtg tcggaacact tggatgctct
     3841 ggatttggtt gtgggattgg tttttctgga gtcggttcac ctggagtacc tggttcctga
     3901 ggacttggaa tttctggttt ttctggagtt ggtttatctg gtgttgataa acggtcatac
     3961 cttaccgtta tttctttatc actagagtct gacgtaactt cttgtgattc aactgttgga
     4021 atatctggat ctttgtactt gtcaatctta ccagatataa cctcgtccca gtttcctgtt
     4081 gtccattcac cgtaggttac aactcccgtg accttgttct cagtttttgt acggcttaag
     4141 gttacaggtt gaacaacatc ttcttttaca ttttggttcg taactttatc aacgtaatga
     4201 atgatacgcg ttatagtctt cgtctcagta gaggttgctg ttttgggaac cactgtttcc
     4261 tcaacattct cacggtagta atagtcaact gttgcaccgt cttctggtac gcatttgcag
     4321 gagttgctac caaggtgtat gttgttttcc ttgtgataac tcggtcttct ttgtcctcag
     4381 ttgttgtttt cccttcaata gtttttgatt ctgtggtata ctcagaacct atcgctaaat
     4441 cagcttttat aacagactct gccaacttct cttggctacc ttctttatag taattggctg
     4501 ttactgtagc agtggttggc gcttcgcttt ctctataaac taaggtcact gttctacctt
     4561 cgcttacaat attcccagtt aaacttgcag aatttgtatc tgcttcttta aaa
//
LOCUS       DAVBIC010000081         4520 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.081, whole genome shotgun sequence.
ACCESSION   DAVBIC010000081 DAVBIC010000000
VERSION     DAVBIC010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4520)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4520)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4520
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.081"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            <1..141
                     /locus_tag="VQ664_002031"
     CDS             <1..141
                     /locus_tag="VQ664_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2790129.1"
                     /translation="LLPLPPYSPEYNPIEKTWAHIKKHLKKVLPSCNTFYEALLSCSC
                     FN"
     gene            complement(134..307)
                     /locus_tag="VQ664_002032"
     CDS             complement(134..307)
                     /locus_tag="VQ664_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteinase"
                     /protein_id="HET2790130.1"
                     /translation="MNIKKRVLSAGLTFASVLLLAACGQSGSDTKTYSSTFSGNPTTF
                     NYLLDYYTDNIVN"
     gene            complement(465..2072)
                     /locus_tag="VQ664_002033"
     CDS             complement(465..2072)
                     /locus_tag="VQ664_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HET2790131.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGIGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIAAIFGTMEDMDQLIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENPNSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGDKDLLTVGETWGATPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVPIEEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYEMINVQEALANPDSIFYTYQKL
                     VQIRKENSWLVRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEGKVKSV
                     LIENTLAQEVFEKQILVPWDAFCVELL"
     gene            2225..3709
                     /locus_tag="VQ664_002034"
     CDS             2225..3709
                     /locus_tag="VQ664_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HET2790132.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQPAADAFLNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMND
                     LGISPADRKVAVVARQKAEETGGPALALELPNGDIVTGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            3804..4286
                     /locus_tag="VQ664_002035"
     CDS             3804..4286
                     /locus_tag="VQ664_002035"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HET2790133.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
BASE COUNT         1311 a         1041 c          855 g         1313 t
ORIGIN      
        1 cttttacctc ttcctcccta ctcacctgag tacaatccta ttgagaaaac atgggctcat
       61 atcaaaaagc acctcaaaaa ggtattacca agttgcaata ccttttatga ggctcttttg
      121 tcttgttctt gtttcaattg actatattat cagtgtaata gtctaataga tagttaaatg
      181 tagttggatt tccactaaag gttgatgagt aagtttttgt atctgaacct gattggccgc
      241 aagcagctaa aagcaaaaca gatgcaaaag tcaggcctgc actaaggaca cgcttcttta
      301 tgttcatctt ctttctcctt aatagtggga atttgtaaag ttaattgaat ttcgagaatg
      361 aaagtttata aaccttggtt ataaaaaaca aaggatttct gcttttatac agtcctccct
      421 tgtttttata tgatttcaat tttaaatttt tctgcaaaaa atatttatag taattccaca
      481 cagaaagcat cccatggaac taagatttgt ttttcaaaga cttcttgagc tagggtgttt
      541 tcaatcaaga cagatttgac ttttccttct actgtcaagt cttgctcttc attggacaag
      601 ttagccacaa ctaggaagcg acggtcgcca tccttacgta tataagcaaa gaccttatca
      661 gccgtatcaa gcaattcaaa gtcagctcga actagccagc tattctcctt gcgaatttgg
      721 accagtttct gataggtata gaaaatagaa tctggatttg ccagcgcttc ttggacattg
      781 atcatctcgt aatttggatt aaccgccaac caaggttgac ctgttgagaa accagcgttt
      841 ttgctctcgt cccattgcat aggggtacgg gcattgtcac gtccaataac acggatactg
      901 tccatgattt cttcaatcgg aacacctttt tcaagagcct cacgcgcata gttgagagat
      961 tcaatatctt ctacttgatc cagtgtttca aacggatagt tggtcatccc aatctcctca
     1021 ccttggtaga tataaggagt tcctctcata agatgaagca agattgcaaa ggctttggca
     1081 gatttttcgc ggtattcttg gtcatttccc cagattgaga caatacgagg gaggtcatgg
     1141 ttgttccaga agagggaatt ccagccgtcc tcaactccta actctgtctg ccatttgttg
     1201 aagatttctt ttaacttagc gatattcagc tctttttgat agtgccattt aggctgacct
     1261 tcctgatact gaagaccgat atgttcaaac tggaagacca tagacaattc ttgccccttt
     1321 ggatcagagt agagcttggc aatctctggc gttgctcccc aagtctcccc tactgtcaag
     1381 agatccttat ctccaaaggt cgcctgattc atttccttga gatagggatg gagcatagga
     1441 ccattattga ctaccttctc gtcaggaatt ttgccaatca tgtcaataac atccatacgg
     1501 aaaccaccaa tacccttatc aatccagaag ttcatcatct cataaatttt ctggcgaagt
     1561 ttttcatttt cccagttgag atccggctgt ttcttgctga aaaagtggag atagtattga
     1621 cctgactttt catcgtattc ccaagcagac ccactaaaga tagaatctaa atcgttaggc
     1681 tcatcccgcc agatatagta gtctcgctca gggctattag gattttcaca ggcctctaca
     1741 aaccaggcat gctcatccga ggtatgattg accaccaagt ccatgatgat acggatatca
     1801 cgcttcttag cttctgcaat cagctgatcc atgtcctcca tggttccaaa aatagccgca
     1861 atcgcttgat aatcagcaat atcgtagcca ttatcatcca tagggctgtc ataaacggga
     1921 gaaagccaaa ttgctgtgat tcctagcttg gctagatagt ccaacttact ggtaattcct
     1981 ggcaaatcgc caattccatc tccattacta tccataaaac tctttggata gacttgatag
     2041 actacggcat tatgccacca tttttcttgc atctgtttac ctcattattt tcataatcta
     2101 tagtctatga tagcactttt taaaattttg tgcaagcgtt tgcttaatct ttttaatttc
     2161 ttttttagct ccgtagtttc ctaacttcca attttttatt ataatagagt ccagaggtaa
     2221 aaaaatgaaa aaacaagctt ttagttctga acagtatttg aatttacaac gcgaccatat
     2281 tttggagcgc attaaccaat ttgacggcaa gctctactta gagtttggcg gtaaaatgtt
     2341 agaagatttc cacgctgctc gtgtccttcc tggttatgaa cctgacaaca aaatcaagct
     2401 cttgcaagaa ttgaaagagc aggttgaggt tgtgattgcc attaatgcta gcaacattga
     2461 acattccaaa gcacgtggcg acttgggcat ttcttatgac caagaagttc ttcgtttgat
     2521 tgacaaattc aatgaattag ggatttttgt tggttccgtt gtcattacac aatacgctgg
     2581 ccaacccgct gcagatgcct tcctcaacca acttgagaaa aacggaattg attcttatct
     2641 tcattatcca atcaaaggat atccgacgga tatggatcac atcatttccc cagaaggcat
     2701 gggcaaaaac gactacatca aaaccagtcg caacttgatt gtcgtaaccg ctcctggacc
     2761 cggttctgga aaattggcaa cgtgtatgtc caatatgtac cacgaccaaa tcaatggcat
     2821 caagtctggc tacgctaaat ttgaaacctt ccctgtttgg aatcttcccc ttcatcatcc
     2881 agttaacttg gcttatgaag ctgccacagc tgaccttgat gatgtcaaca tgattgaccc
     2941 cttccatctt caaacctatg gagaaaccac tgtcaactac aaccgtgata tcgaaatctt
     3001 cccagtgctc aagcgcatgt tggaacgtat tctcggaaaa tcaccatacg cttcaccgac
     3061 agatatgggt gtcaacatgg ttggtttcgc tattacagat gacgaggctg ctgtcgaagc
     3121 ttctaaacaa gaaatcatcc gccgttacta tcaaacagtt cttgacttca aagctgaaaa
     3181 agttggcgaa gctgccgtca agaaaattga gttgctcatg aacgacctcg gtatctcacc
     3241 tgcagaccgt aaggttgctg tcgttgcgcg ccaaaaagca gaagaaactg gcggaccagc
     3301 cctagctctt gaattaccaa atggtgacat tgtcactggt aaaaactcag aactctttgg
     3361 ccctacagcc gctgccttga tcaacgccat caaaaaatca gctgacatcg ctaaagaagt
     3421 aaaactaatc gagcctgaag ttgttaagcc aatccaagga cttaaaatcg atcatctcgg
     3481 tagccgcaat ccacgccttc attcaaatga aatcctgatt gcacttgcta tcacagctac
     3541 agaaaatcct gatgctgccc gcgctatgga agaactcggc aacctcaaag gaagcgaagc
     3601 ccactcaacc atcatcttga ctgatgaaga caagaatgtc cttcgtaaac tgggtatcaa
     3661 cgtaaccttt gacccatact accaatacga ccgcttatat cgtaagtaaa gatttcaacc
     3721 tctccagcct cggagaggtt ttctctctgt ctcaggagca agctttatga tataatgaga
     3781 gaagaaaact gaaaggattt accatgtcaa aagaagttat tgtcgaaagt tttgaacttg
     3841 accacaccat tgtcaaagca ccctatgttc gcttgattgg ggaagaaaca ggaccaaaag
     3901 gagacatcat ctccaattat gatattcgct tggtgcaacc aaacgaagac tctatcccta
     3961 ctgccggcct tcacactatc gagcacctct tagccaaact catccgtacc cgcattgacg
     4021 gcatgattga ctgttcacca tttggttgcc gcacaggctt ccacatgatt atgtggggac
     4081 gtcacaccag tgctaaaatc gcagctgtta tcaaggattc gctcaaggaa atcgctgaaa
     4141 ctactacttg ggaagatgtc ccagggacaa ccatcgaatc ttgcggaaac tacaaggacc
     4201 acagcctctt ctctgctaaa gaatgggcaa aactcatctt ggaacaaggg atttcagatg
     4261 atgcctttga acgtcatgtg atttaaaatc gagtagggga taatctctag cccctctcac
     4321 accaccgtac gtgccgttcg gcatacggcg gttcaactaa cttttaacgc atgtcgttca
     4381 aggtaataat ccaaacacga aaccaatcca cgtttttcaa ggactggttt tgatatagca
     4441 cgtttaagta ccgacttctg agctactata gtggattgaa actagaatag ttcacctctg
     4501 cttctaaaac attgttagaa
//
LOCUS       DAVBIC010000082         4461 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.082, whole genome shotgun sequence.
ACCESSION   DAVBIC010000082 DAVBIC010000000
VERSION     DAVBIC010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4461)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4461)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4461
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.082"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            complement(32..265)
                     /locus_tag="VQ664_002036"
     CDS             complement(32..265)
                     /locus_tag="VQ664_002036"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2790134.1"
                     /translation="MFSQLHMREEQVLLAQDYALETARAEGLEQGLERGKVEGRAERK
                     LFAFLDIVRQGLLTSEVASQQLGMSVSEFEALL"
     gene            complement(258..374)
                     /locus_tag="VQ664_002037"
     CDS             complement(258..374)
                     /locus_tag="VQ664_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HET2790135.1"
                     /translation="MVGVFRQQALYPATATSHYPSKSTAGLQELVRGGQENV"
     gene            complement(589..942)
                     /locus_tag="VQ664_002038"
     CDS             complement(589..942)
                     /locus_tag="VQ664_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HET2790136.1"
                     /translation="MILRHLGISPTNDLVAKKIFSNPEITCQFIRDMLDLPAKNVTIL
                     EGSNIHVLPSMPYSAQDFYTSIDVLAELDNGTQVIIEIQVHHQNFFINHLWAYLCSQV
                     NQNLEKIRQREGDTH"
     gene            1195..3828
                     /gene="polA"
                     /locus_tag="VQ664_002039"
     CDS             1195..3828
                     /gene="polA"
                     /locus_tag="VQ664_002039"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HET2790137.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDH
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNVSSADVAEGLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCGDKLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVETEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIVVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYMQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDNVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEMKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            3913..4350
                     /locus_tag="VQ664_002040"
     CDS             3913..4350
                     /locus_tag="VQ664_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HET2790138.1"
                     /translation="MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVARDFLKADA
                     KIFWAQLGLESLEAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
BASE COUNT         1211 a          823 c         1080 g         1347 t
ORIGIN      
        1 atttacccac tatggatatt atggagccat tttacaacag tgcctcaaat tcagatactg
       61 acatacctaa ttgctggctg gcaacctcag aagtcagaag accttggcgt actatgtcta
      121 ggaaggcaaa aagtttcctt tctgcccttc cttcaacttt cccacgctct agtccttgtt
      181 caaggccttc agccctagca gtttccaagg catagtcctg tgctaacaag acttgttctt
      241 ctcgcatatg tagttgacta aacattttcc tgtcctcctc ggaccagctc ttgtagtcca
      301 gcagttgatt tgcttgggta atggctcgtt gcggttgctg ggtaaagggc ttgttgccga
      361 aaaactccaa ccatggcttg cgaaccttgt ctttgctggt ttctctgtat tttttaattc
      421 caagaatgcc atcttaacca gatggttttc ctgtccattg ttggtaatcg ccaatacctc
      481 acctgttgtg tcttcgcgca tactaaagct atgaaaagcc aggtcatctg agaaataatt
      541 actatccacg atagcaatga cgtaaacagg agcgatgtgt ttgtagatct agtgagtatc
      601 accttctcgc tgacgaattt tttcaagatt ttgattaacc tgactgcaca ggtaagccca
      661 caagtgattg atgaaaaaat tctgatgatg gacttgaatc tcaataatta cttgagtacc
      721 gttatccaac tccgccaaga cgtctatact ggtataaaaa tcctgcgctg agtagggcat
      781 ggaaggcaag acatgaatgt tacttccctc caaaatagtc acatttttgg ctggcaagtc
      841 cagcatatcg cggataaatt gacaagtgat ttctgggttg ctgaaaattt tcttagcaac
      901 caagtcattg gtcgggctaa ttcccagatg tctgagaatc atccttttcc tccttctata
      961 gtgaattgaa ataagatgtg aacaactcta tcaggaaagt caaattaatt tatagaaata
     1021 ttttagcagt caaggtgtac tattatagat tcaatatact atattatagc acatttttaa
     1081 atctaggttt actaaattct ctggctctat ctatttattc ggaaaaagtt tgaaaaatac
     1141 ttgctctagc tcttcccaat ggtatttttt gattctttcc tttataatgg gtgtatggat
     1201 aagaaaaaat tattattgat tgatgggtct tctgtagctt ttcgggcgtt ttttgcgctg
     1261 tatcagcagt tggaccgttt taagaatgcg gctggtttgc ataccaatgc gatttatggt
     1321 tttcagttga tgttgagtca tttgttggag cgggttgagc cgagtcatat tttggtggct
     1381 tttgatgcgg gaaagacgac cttccggaca gagatgtatg cggactataa gggtggtcgg
     1441 gccaagactc ctgatgagtt tcgtgagcaa tttcctttca ttcgtgagtt gctggatcat
     1501 atggggattc gtcactatga gctggctcag tatgaggcgg atgacatcat tgggacgttg
     1561 gataagctag cagagcagga tggttttgat attaccattg tcagtgggga caaggatttg
     1621 attcagctga cggatgagca tacggtggtt gaaatttcca agaaaggtgt ggctgagttt
     1681 gaggccttta cgccagatta cctcatggaa gaaatgggcc tcacaccagc tcagtttatc
     1741 gatctcaagg cgctcatggg tgataagtcg gataatatcc ctggggtgac caaagtcggt
     1801 gaaaagacgg gtattaagct cttgctggag catggttcgc ttgaggggat ttatgaaaat
     1861 attgatggaa tgaagacttc taagatgaag gaaaatctca tcaatgacaa ggaacaggcc
     1921 tttttgtcta aaacactagc gaccattgat accaaggcac cgattgcgat tggtttagag
     1981 gacttggtct atagtggtcc agatgttgaa aatcttggga aattttacga tgagatggga
     2041 ttcaaacagc tcaagcaggc tttaaatgtg tcgtcagctg atgtggctga gggtttggat
     2101 tttactattg ttgaccaaat cagtcaagat atgctgagtg aagagtctat cttccacttt
     2161 gagctttttg gtgagaatta tcatacggat aatttggttg gatttgcctg gtcttgtggg
     2221 gataagctct atgccacaga caagcttgag ctgttgcaag acccgatttt caaggatttc
     2281 ttagaaaaaa catctctgag agtttatgac tttaagaagg ttaaagttct tttgcaacgt
     2341 tttggtgtgg atttgcaggc gcctgctttt gacatccgtt tggctaaata cctcctttcg
     2401 actgtggagg acaatgaaat tgcgaccatc gctagtcttt atggtcagac ttacttggtt
     2461 gatgatgaaa ctttctacgg taagggtgtt aaaaaggcca ttcctgaacg tgagaaattc
     2521 ttggaacact tagcttgtaa acttgctgtt ttggtagaaa cagagcctat tttacttgaa
     2581 aaactcagcg aaaatgggca attagagctt ctttatgata tggagcaacc tctggctttt
     2641 gttcttgcca agatggaaat tgctgggatt gtggtcaaga aagagacctt gcttgagatg
     2701 caggctgaaa atgagcttgt cattgaaaaa ctgactcaag agatttacga gctggctggt
     2761 gaggagttta atgtcaactc gcctaagcag ttgggcgtgc ttctctttga gaaattggga
     2821 cttcctctag aatacactaa gaaaaccaag acaggttatt cgacagcagt ggatgtgttg
     2881 gagcgtctcg ctcctattgc tccgattgtt aagaaaatcc tggattaccg tcaaattgct
     2941 aagattcaat ctacttatgt aattggcttg caggactgga ttttggctga tggaaagatt
     3001 catactcgct atatgcagga tttgacccag accgggcgtt tgtctagtgt ggatccaaac
     3061 ttgcaaaata ttcctgcccg attggaacaa gggcgcttga ttcggaaggc ttttgtgcca
     3121 gagtgggagg atagtgtgct actcagctct gactattcac agattgaatt gcgcgttttg
     3181 gcgcatattt ctaaggatga gcacttgatt aaggccttcc aagagggggc agatatccat
     3241 acttcgacag ccatgcgggt ctttggcatt gagcgtcctg ataatgtgac tgcaaatgat
     3301 cgtcgcaatg ccaaggcagt taactttgga gtggtttatg ggatttcaga ctttggcttg
     3361 tctaataatt tgggaattag tcgtaaggaa gccaaagcct acattgatac ctactttgaa
     3421 cgttttccag gtattaaaaa ctacatggat gaagtggtgc gggaggcgcg tgataagggc
     3481 tatgtagaga ccctctttaa gcgtcgccgt gagttgccag atatcaattc gcgcaacttc
     3541 aatattcgtg gttttgcgga gcgaactgct atcaactcac ctatccaggg ttcggcagca
     3601 gatattctca agattgccat gattcagctg gataaagcct tggttgcagg tggttatcag
     3661 actaagatgc tgttacaagt gcacgatgaa atcgtccttg aagtgcctaa atctgaattg
     3721 gtagagatga aaaaattggt gaaacaaacc atggaagaag ccattcaact cagtgttcct
     3781 cttatcgcag atgagaatga aggggcaacc tggtacgagg ctaaataaaa agggggctag
     3841 tcctcctttt ttgtagtaga attctgcaaa ccttttcaaa atgtgctata ctgatgaaaa
     3901 aggaggtttt ctatgagtca agaatttatc aatccaagtg atggcgtgat tcgtcagtat
     3961 ctcgcaacga gtaaaaccct tgctgtggtg ggtttgtctg accgtgaaga aacaaccagc
     4021 aatcgagtga caaaggaaat gcaggctcgg ggctataaaa tcatcccagt caatcccaag
     4081 gcggcaggtg gcgaaatctt gggtgaaaag gcttatgcta gcctcgctga aattcctttt
     4141 cctgtagata ttgtcaatgt ttatcgtcgc agtgaatttc tgcccgatgt ggcgcgtgat
     4201 tttctcaaag ctgatgccaa gattttttgg gcacagctag gacttgaaag tttagaagcg
     4261 aaagagattt tgcgtgatgg tggatgtgat gatatcgtga tgaatcgctg tatcaagaga
     4321 gaacatactc gcttgattga ggaagcataa gaaaaaggta gctgatgggc taccttttgt
     4381 gttatactca atgaaaatca aagagcaaac taggaaacta gtcgcgggct gctcaaaaca
     4441 ctgttttgag gttgtagata c
//
LOCUS       DAVBIC010000083         4438 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.083, whole genome shotgun sequence.
ACCESSION   DAVBIC010000083 DAVBIC010000000
VERSION     DAVBIC010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4438)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4438)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4438
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.083"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            <1..119
                     /locus_tag="VQ664_002041"
     CDS             <1..119
                     /locus_tag="VQ664_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2790139.1"
                     /translation="QQGFTDRLVGYSSSIALVFTTLIGMISLVQRRVLKEDD"
     gene            121..966
                     /locus_tag="VQ664_002042"
     CDS             121..966
                     /locus_tag="VQ664_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET2790140.1"
                     /translation="MKRFKPTTILEYILLTLLAGLFLFPMVWMVVSAMKPEADVYKNL
                     TSWQAFLPSLNPADWFKPYQEVFERFSIFTYLGNSIFYAGTFAIGSIIVNALAGFAFA
                     KVNFSGKKILFGFLLALLIIPVETVLIPQFTIINSLGLVNNRLAVIIPGLASVFNIYL
                     FRNFFIAIPEEILESAKMDGASIVRIFFRIMLPMSKPAVATVGVLSFISSWNDYIWPL
                     MVLTDSSKFSMQVAITTINTTQPVYINQVMAVLTISTIPLILVYVVAQKYIVQGLGGS
                     GTGIK"
     gene            976..2295
                     /locus_tag="VQ664_002043"
     CDS             976..2295
                     /locus_tag="VQ664_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HET2790141.1"
                     /translation="MINKTFTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEETGVRQVQNMAFSDDGIHFEKISQNPVATGSDLPDELIA
                     ADFRDPKLFEKDGRYYSVVAAKHKDNVGCIVLLGSDNLVEWQFESIFLKGGEHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWREKRFIPESVQEIDH
                     GQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDTDYLEFGYDSNAQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            complement(2503..2575)
                     /locus_tag="VQ664_002044"
     tRNA            complement(2503..2575)
                     /locus_tag="VQ664_002044"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2540..2542),aa:Lys,seq:ctt)
     gene            complement(2839..4110)
                     /locus_tag="VQ664_002045"
     CDS             complement(2839..4110)
                     /locus_tag="VQ664_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HET2790142.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYAARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQRIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWIKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDRLRKI"
BASE COUNT         1294 a          809 c          976 g         1359 t
ORIGIN      
        1 atcaacaagg ttttactgat cgtcttgtag gatattctag ctcaatcgct ttagtattta
       61 caacgttaat tggtatgatt agcttagtac aacgtcgcgt tctgaaggag gatgactaag
      121 atgaaacgat ttaaaccaac aacaatctta gaatatattc tgttaacttt attggcagga
      181 ctcttccttt ttcctatggt ttggatggta gtttcagcta tgaagccaga agcggatgtt
      241 tataaaaatt tgactagttg gcaagccttc ttaccaagtt taaatcccgc tgattggttt
      301 aaaccttatc aggaagtatt tgagcgcttt agtattttta catatctagg gaacagcatt
      361 ttttatgctg gaacgtttgc tattggttct attattgtca atgcactggc cggtttcgct
      421 tttgcaaaag tcaatttttc aggtaagaaa attttatttg gtttcttact tgctttactt
      481 attattccag tggaaactgt gttaattcca caatttacca ttatcaattc cttaggtttg
      541 gtcaataatc gtcttgcagt tattattcca ggattggcga gtgtatttaa tatttactta
      601 tttaggaatt tctttattgc aattccagaa gagattcttg agtctgcaaa gatggacgga
      661 gcaagtatcg ttagaatttt ctttagaatt atgcttccaa tgtctaaacc tgcagttgct
      721 acagttggtg ttttatcatt tatttcaagc tggaatgatt atatctggcc attgatggtt
      781 ttgacagatt cttctaaatt ttcaatgcag gttgcaatta caactattaa tacaactcaa
      841 ccagtttata tcaatcaggt aatggctgta ttaactattt caacgattcc gttgattttg
      901 gtctatgtag tcgctcagaa atatattgtt caaggtctgg gtggttccgg aactggaata
      961 aaataggata tacttatgat aaataaaaca tttacagtag aaaaagccaa tcgttttata
     1021 gcagaaaata aacatctcgt taatactcaa tataagcctg aagaacattt ttcagctgag
     1081 attggttgga tcaatgatcc aaatggattt gtctattttc gtggagaata ccatctcttt
     1141 tatcaattct atccatatga tagtgtttgg gggcctatgc actggggaca tgctaaaagt
     1201 aaggacttgg tgacttggga gcacttgcca gtggcacttg ctcctgacca agattatgac
     1261 cgaaatggtt gtttctcagg ctctgccatt gtcaaggatg atcgcctctg gctcatgtac
     1321 actggacata tcgaagaaga aaccggtgtc cgccaagtgc aaaatatggc attttcagat
     1381 gacgggattc actttgaaaa gatttcccaa aatccagttg caactggatc agacttgcca
     1441 gatgagttga ttgctgctga tttccgtgat ccaaaactct ttgaaaaaga tggacgctat
     1501 tactccgtag tagctgccaa acacaaggat aatgtgggct gtatcgttct actagggtcc
     1561 gataacctag tagaatggca gttcgaatcc atctttttaa aaggaggaga acaccaaggc
     1621 tttatgtggg aatgcccaga ttacttcgag ttagatggga aagattgcct tattatgtca
     1681 cccatgcgtt atcagcgtga gggagactca tatcataaca tcaactcatc gcttttgttc
     1741 acgggtaagg tagattggag agaaaaacgt tttatcccag aatcagttca agaaattgat
     1801 catggccaag acttctatgc gcctcaaaca ttgttggacg atcaaaatcg tcgtatcctg
     1861 attgcttgga tgcagacatg ggggcgtacc cttccaaccc atgaccaaga acacaaatgg
     1921 gcatgtgcca tgactttacc tagaattcta agattggaag atggcaaact aagacaattc
     1981 cctgttaaaa aaggccaata tcaaatccaa atagataaag attgtcatta ccacttagga
     2041 aatgatacag attatcttga atttggttat gacagtaatg cgcagcaagt ttacattgat
     2101 cgtagccatc ttattcaaaa aattctaggt gaagaagaac aggacactag tcgacggtat
     2161 gtagatattg aagctaaaga attggaagtt gttctagata aaaattccat cgagattttt
     2221 gtcaatcaag gtgaagcaag cttgactgca acttattact taacggtgcc agctgagcta
     2281 tcacgaattg attaaaaatt aagttatttc tcctaaagaa aaagttctct ttctaaaata
     2341 gtggaaagag gactttttgt gttttgggta tataagctta gtttatggta tttgtaaaat
     2401 tggtgttgga ttatgattta agctagtttt ctaaagaatt tgaaaaaaat tttatttaag
     2461 caaaaaaacc ttggttccaa ggcttttcct gttgtattta gatgccccct acagggatcg
     2521 aacctgtgac ccacggatta agagtccgct gctctgccag ctgagctaag gaggcaaaga
     2581 aaaagctgta ttggtgccga aacttcacgg tttgtattga acccgcgcaa ttaagcaggt
     2641 gggcaactcg ctctaactga agctgtttcc gtgtgagacg gcctacatgc tgttagaaga
     2701 cttttgtttc cctaataata caaaaaatag tcggtcaaca cttaagtgtg aagtcgtaca
     2761 ccacagcgtt tctatactta tatgatacca ctttttcaaa aaaaatcaag aggaaagtgc
     2821 aattttttga aaaggatttc agatttttcg caaacgatcg atagcttcct ttctttgagc
     2881 caaagcccgt tcatatttac cagtatcttc tgcttggaaa tagtgatgat tacgaatttt
     2941 ttctggcaga tagtcttgct tgatccaatt tccaggatag ttgtgtggat agagatagtc
     3001 ttgggcattc cccagttcct tgcttccact gtagtgccca tcacgcaggt gtcgcggaat
     3061 aggcaagtgc cctgatgttt tgaggtcagc aagtgcctta tccatagcta cataggctga
     3121 gttggatttt ggagaaaggg ccaaatcaat cacgacattg gcaatgagaa tgcgggcttc
     3181 ggggaaacca atcctttgtg cagcatccag agcagtcacg gtatgaatct gggcctcagg
     3241 attggctaag ccaatatctt cataggcgat aacagtcaag cgacgagcga gactaggcag
     3301 atccccagcc tcaatcaagc gggcagcata gtggagactg gcatccacat ctgagccacg
     3361 gatagacttt tgcagggcag atagaacatc atagtgaccg tctccatcct tgtccatagt
     3421 gatgtagctt ctctgaagac tattttccat gatgtctaag gtgatgtggc gaatgccctc
     3481 gtcattctca ggggtagaga gaacagccaa gtccagtgag ttaaaggcag agcgaaggtc
     3541 tccgtttgta gaggttgcga tgaaatccag cgcatcctca tctagttcta ttggaaaatc
     3601 aaaaccacgt tcagggttac ttagagctat ctgcagggcc tctttgacgt cttggttaga
     3661 cagaggttcc aactcgaaaa tttgaacacg gctacgaatg gcaggagtga cagagaagaa
     3721 aggattttca gtcgttgctc caatcatgat gaccagtcca ctttccaaga gaggcaagag
     3781 gaagtcttgc ttggtcttat ctagtcgatg aatttcgtct agcaatagga cgagaccacc
     3841 agaaaattta gcttcttccg agatttcttg cagtcgcttt ttactatcaa ctgtcgcatt
     3901 gaaagttcga aaggcatact tggtcgttcc agcgatggca gaggcaatac tggttttgcc
     3961 gattccagga gggccatata gaatcatgga ggacaggcgg ttggcttcca ccatgcggcg
     4021 gatgattttt ccaggtccga ccagatgctc ctgaccgatg acctggtcga tggttttagg
     4081 gcgcatgcga agcgcgagat tgtctggcat agcagtcctt tctaacgtgg atttgagtag
     4141 aatgactcat ctactatatc ttactatgtc cattctagcc tattagttgt gatatttcaa
     4201 tggttttgta ataatcaggg agtgagatag aatctttttt actatttaat ttaatgagga
     4261 gaggtatcag catgagagat ttgattttcc ttaaagctca aaataggata gttgagccta
     4321 aagaagtgga agtgctgact tgagaaataa tattgctgaa tgtcattgta tgaactataa
     4381 tgaaaagaga ggtgataagc aatggaaatg atggaccaag tcaggaaatt ttgatttt
//
LOCUS       DAVBIC010000084         4311 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.084, whole genome shotgun sequence.
ACCESSION   DAVBIC010000084 DAVBIC010000000
VERSION     DAVBIC010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4311)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4311)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4311
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.084"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            complement(<1..132)
                     /locus_tag="VQ664_002046"
     CDS             complement(<1..132)
                     /locus_tag="VQ664_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2790143.1"
                     /translation="MVNCEPLEAYRQLEEAELVGCWAHVRRKFFEAPPKQTDKSSLGA
                     "
     gene            complement(205..639)
                     /locus_tag="VQ664_002047"
     CDS             complement(205..639)
                     /locus_tag="VQ664_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000927991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2790144.1"
                     /translation="MLLVLVSLVHSFGSVSIIAHTIHQKFNLKVPNYRQEEDWARMGL
                     PITRKEISNWHIKASQYYLESLYKLLREKLLEQPLLHADETSYRVLESDSHLTYYWTF
                     LSGKAENQAITLYHHDQRRSGLVVQEFLGDYSGYVHCDMLRQ"
     gene            complement(715..1566)
                     /gene="rfbD"
                     /locus_tag="VQ664_002048"
                     /pseudo
     CDS             complement(715..1566)
                     /gene="rfbD"
                     /locus_tag="VQ664_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647909.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
     gene            complement(1632..2681)
                     /gene="rfbB"
                     /locus_tag="VQ664_002049"
     CDS             complement(1632..2681)
                     /gene="rfbB"
                     /locus_tag="VQ664_002049"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000141505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HET2790145.1"
                     /translation="MTEYKNIIVTGGAGFIGSNFVHYVYENFPDVHVTVLDKLTYAGN
                     RANIEEILGNRVELVVGDIADAELVDKLVAQADAIVHYAAESHNDNSLNDPSPFIHTN
                     FIGIYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTAETKYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSSGVWTILTKGQIGETYLIGADGEKNNKEVLELILKEMGQATD
                     AYDHVTDRAGHDLRYAIDASKLRDELGWKPEFTNFEAGLKATIKWYTDNQEWWKAEKE
                     AVEANYAKTQEIITV"
     gene            complement(2691..3287)
                     /locus_tag="VQ664_002050"
     CDS             complement(2691..3287)
                     /locus_tag="VQ664_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HET2790146.1"
                     /translation="MTDNFFGKTLAARKVEAIPGMLEFDIPVHGDNRGWFKENFQKEK
                     VLPLGFPESFFAEGKLQNNVSFSRKNVLRGLHAEPWDKYISVADGGKVLGSWVDLREG
                     ETFGNTYQTVIDASKGIFVPRGVANGFQVLSDTVSYSYLVNDYWALELKPKYAFVNYA
                     DPSLGIEWENLEEADVSEADKHHPLLKDVKPLKKEDLE"
     gene            complement(3288..4145)
                     /gene="rfbA"
                     /locus_tag="VQ664_002051"
     CDS             complement(3288..4145)
                     /gene="rfbA"
                     /locus_tag="VQ664_002051"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000676139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HET2790147.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLA
                     GIRDILIISTPQDLHRFQELLQDGSEFGIKLSYAEQPSTDGLAIGEEFISDDSVALIL
                     GDNIYHGPGLSTMLQKAAKKEKGATVFGYQVKDPERFGVVEFDTDMNAISIEEKPEYP
                     RSNYAVTGLYFYDNDVVEIAKSIKPSPRGELEITDVNKAYLDRGDLSVELMGRGFAWL
                     NTGTHESLLEASQYIETVQRMQNVQVANLEEIAYRMGYISREDVLALAQPLKKNEYGQ
                     YLLRLIGEA"
BASE COUNT         1207 a          998 c          783 g         1323 t
ORIGIN      
        1 agctcctaag gatgatttat ccgtttgctt ggggggcgct tcaaaaaact tccttctcac
       61 atgtgcccaa catccaacaa gttcagcttc ttccagttga cgataagctt ctagcggttc
      121 gcagtttacc aagcttagcg tcgccttgct cctaaacctt ggactgctat cgcataggca
      181 gaactagagg actaaagtcc taagttactg ccgcaacata tcacaatgca catagccaga
      241 ataatctcct aggaattctt gtactactaa accactccga cgctgatcat ggtggtacag
      301 cgtgattgct tgattctcag ctttcccaga caaaaaagtc caatagtagg tcagatggct
      361 atcactctct agaacccgat aagaggtttc atccgcatga agaagaggtt gttctaacaa
      421 cttttctcgt aaaagcttat aaagggactc taaatagtat tgacttgcct tgatatgcca
      481 attagagatt tccttacgtg tgattggtaa acccatccta gcccaatctt cttcttggcg
      541 ataattgggt accttcagat taaacttctg atggatggtg tgagcgataa tagaaactga
      601 gccaaagcta tgcaccaaag agaccagcac caacaacaag ataattgtac atcttaagct
      661 cctttggagt tcattatctg cctcttttat tagactagaa aatcattcta ctacttatct
      721 cacttcttgt ttgtaaaatt cttgcaatgc atcttgccaa gttggaataa caaatccagt
      781 agctttggct ttggccaggc tcatcgttga gtttagcgga cgttgagctt tggctggaaa
      841 ttgactggaa tctactgact tgacttcgac atctgtatct ttcaaaattt caactgcaaa
      901 atcataccat gttgtgtctt ctgtcgcatc atttgacaaa tgataataac caaattcctt
      961 acgattttca gctaggtaga tcatgaattc agccaaggta cgagtccaag tcggacgacc
     1021 gtactggtca tttacaactg ttaaagtctt atgagttttc gcaagatttt gcatggtaaa
     1081 aacgaagttt ttgccataat ttccaaatac ccaggcagta cggataatat agaaattaga
     1141 cacatgcttc tcaactaact cttcccccat acgcttagtg cgtccatatt ctgtctgtgg
     1201 atctggtcgg tcatcaactt cccactcttg tccaactggt ttcttaccgt caaagaccta
     1261 gtccgtagaa atataaacta gagttgcacc atgcttttca gatgcttttg cgacattttt
     1321 tgtccccatc acattgatgg cgaagtccaa ctcttttcct tcatcctctg ctgcatcaac
     1381 agcggtgtag gctgcacaat ggtagactaa agtcggtttc acctcttcaa aaactttctc
     1441 aaccatttct tcattggtaa tgtccatctc agccacatct actgccacgt attcttcatt
     1501 acgttcatcc aataaatagc gaagttccgt tcctaattgg ccatttgccc ctgtaattaa
     1561 aatcatctct agacctttct aatatgtaac tcttcccaat atagcaataa aaagcagcga
     1621 tttcctgctt tttatactgt aataatctcc tgagtcttag cataattggc ttcaacagct
     1681 tctttttctg ctttccacca ttcttggtta tctgtatacc acttgattgt tgccttgagc
     1741 ccagcttcaa agttggtaaa ttcaggtttc caccccaact catcacggag cttgctggca
     1801 tcaatcgcat agcgaaggtc atgtcctgca cggtcagtca catgatcata ggcatccgta
     1861 gcttgtccca tttccttaag gataagttcc aaaacttcct tattgttctt ctcaccatca
     1921 gccccaatca agtaggtttc accgatttgc ccttttgtca agattgtcca aactcctgaa
     1981 gaatggtcat tggtatgaat ccagtcacga acgttcttac cttcaccgta aagttttggc
     2041 ttaattccac ttaggatgtt agtaatctga cgtgggatga atttttcgat atgttgataa
     2101 ggaccgtagt tatttgaaca gttggaaatc gttgccttga ctccaaaaga acgcacccag
     2161 gctttgacaa tcaagtctga tgcggccttg gttgatgagt acggagagct tgggttgtat
     2221 tttgtttcag cagtaaattt ctcacctggt ccttcaccat gacctggcaa atcttctcgt
     2281 aaagggagat ccccataaac ttcatctgtc gatacatggt ggaagcgaat atcatactta
     2341 cgagcagctt ctaaaagagt atagattcca atgaagttag tatgaataaa tggcgatgga
     2401 tcattgagcg aattatcatt gtggctttcc gctgcataat gaacgatagc atctgcttga
     2461 gcaaccaact tgtctaccaa ctccgcatca gcaatgtcac caacaactaa ctcaacacga
     2521 ttgcctaaaa tttcctcaat attcgcgcgg tttccagcat aagtcaactt atctaggact
     2581 gtcacgtgaa catctggaaa gttctcgtaa acataatgga caaagttaga accgataaag
     2641 ccagctccac ctgtcacgat aatatttttg tattcagtca tattctttcc ttattccaaa
     2701 tcttcttttt tcaaaggctt cacgtcctta agtaggggat gatgtttgtc tgcttcagat
     2761 acgtctgctt cttccagatt ttcccattca ataccaaggc ttggatcagc gtagttcaca
     2821 aaggcatact tgggtttgag ttcaagagcc cagtaatcat tgaccagata gctatatgac
     2881 actgtatctg ataaaacttg gaagccatta gctacgcctc gaggaacaaa gattcccttg
     2941 cttgcatcaa ttactgtctg ataggtattc ccaaaggttt caccctcgcg tagatcaacc
     3001 caagaaccca gaactttccc tccatctgct acagagatgt acttatccca aggctctgcg
     3061 tggaggcctc gaaggacatt tttacgtgag aaggatacat tgttttgcaa ttttccttct
     3121 gcaaagaaag actctggaaa tccaagtgga agcacttttt ccttttggaa attttcttta
     3181 aaccagccac gattatctcc atgaacgggg atatcaaact ccaacatgcc tggaatagct
     3241 tcaaccttgc gtgccgcaag cgtcttaccg aaaaaattat ctgtcatcta tgcttctcca
     3301 atcaaacgga gcagatactg tccgtattca tttttcttaa gtggttgggc taaggccaat
     3361 acatcttctc gactgatata gcccatacgg taagcaattt cttctaagtt tgctacctga
     3421 acattttgca tccgttgcac tgtttcgatg tactgtgaag cctctagtaa actttcatga
     3481 gttccagtat tcagccaagc aaagccacgt cccataagct caacagacaa atcaccacga
     3541 tctaggtaag ccttgtttac atctgtaatt tccagttcac cacgagggct tggtttaata
     3601 ctcttggcaa tttcgacaac atcgttatca tagaaataca gtcctgtcac tgcatagttg
     3661 gagcgaggat actccggttt ttcttctatg gaaatagcat tcatgtctgt atcaaactca
     3721 accacaccaa aacgctctgg atccttcact tggtagccaa aaacagtcgc acctttctct
     3781 ttcttggctg ctttttgaag cattgtgctc agaccaggac catggtagat attgtcgcct
     3841 aaaatcaagg caacgctatc gtcagaaata aactcttccc caattgccaa accatctgta
     3901 cttggttgct ctgcataaga aagtttgatc ccaaactcag atccgtcttg aagaagctct
     3961 tgaaatcgat gtaaatcctg tggagtggaa ataatcaaaa tatccctaat cccagccaac
     4021 atcaatgttg aaagtgggta gtaaatcatc ggtttatcat aaaccggcat aagttgtttt
     4081 gacgcagcgc gagtcaaagg atataaacgt gtccccgaac cacctgctag aataatacct
     4141 ttcatagtag ggtacctttc tttgttattt tagagtcaat tactattaat tgtgtactgc
     4201 tctaaaaaga aaacaatcat cccatgtttt atatggctct ataatatttg tagtgggtaa
     4261 atccactata gatattatgg agcctatttt attgtagaaa aaaagtccca t
//
LOCUS       DAVBIC010000085         4256 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.085, whole genome shotgun sequence.
ACCESSION   DAVBIC010000085 DAVBIC010000000
VERSION     DAVBIC010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4256)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4256)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4256
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.085"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            complement(10..1299)
                     /locus_tag="VQ664_002052"
     CDS             complement(10..1299)
                     /locus_tag="VQ664_002052"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HET2790148.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIAMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKVA
                     VENAPSILDFLDEESQAHFDAVRQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVAYFGGPETAGFGFGLGVERLLLILEKQGVTLPIENALDVYIA
                     VLGEGANIKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFAAKTLITLGESEVES
                     GQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
     gene            complement(1377..2624)
                     /locus_tag="VQ664_002053"
     CDS             complement(1377..2624)
                     /locus_tag="VQ664_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HET2790149.1"
                     /translation="MKLLFRNPAYRILTLSRFFNAFGVSIFNLVFIVYASTLSQASFA
                     VAMANIVMILPTLFTVFAGIRADYTRDKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SSLCLINVISDIISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGGQAFGVW
                     LLALSVNNFSLVAGINACFFLVSATILFLGKSKLSLSMSSADGENLKNEKLSIKDQFL
                     TIYRNLRLVFLKSGQKNFGFMLFAVLLINSLGGALGGIYNIFFLSHSLLNFSYTEALF
                     INQFCVLVSVIISSLTGNDYFGKQSLPRLMMWETVGLSLVGLANLFNQVVLGLLFLFF
                     TLYVSGKVQPKISAMLMKNLAPEVLARTSNFLGLLFTLSIPVGTACFSLVAVWNIQLT
                     WMLFVGLSLLAIFLTILNLKNDI"
     gene            complement(2815..3665)
                     /gene="rgg"
                     /locus_tag="VQ664_002054"
                     /pseudo
     CDS             complement(2815..3665)
                     /gene="rgg"
                     /locus_tag="VQ664_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398326.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes.; frameshifted;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
     gene            3789..4130
                     /locus_tag="VQ664_002055"
     CDS             3789..4130
                     /locus_tag="VQ664_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HET2790150.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIKDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
BASE COUNT         1352 a          892 c          830 g         1182 t
ORIGIN      
        1 ctttgatttt tattgagtat aaaatcctag tttttcaaag atttctgaga agttttggct
       61 gattgtctca agtgacactt gcacttcttc tcgggtttgg ttgttcttga ccgtcacttg
      121 tccgctttcg acttcgctct ctcctagggt gatgagggtc ttagccgcaa agacatcggc
      181 tgacttgaac tgagctttta gtttacggtt gaggtaatca cgctctgctt tgaaaccttg
      241 ttggcgaaga gcctgtacca attccaaggc cttgatattt gccccttcgc ccaagactgc
      301 gatatagaca tctagggcgt tttcgatagg gagggtcaca ccttgctttt caaggatgag
      361 aagcaggcgc tctacaccaa gtccaaaacc aaatccagca gtttcagggc ctccaaagta
      421 agcaaccaaa ccatcgtagc gaccacccgc acagacggtc aggtcattgc cctcaatctc
      481 tgtgataaac tcgaaaatgg tgtggttgta gtagtccaga ccacgcacca tattggtatc
      541 gatgatgtaa tctactccaa gattttccaa catctgacgc acagcatcaa aatgagcttg
      601 gctttcttca tcaagaaagt ccaagataga cggcgcattc tctactgcca ccttgtcttc
      661 tttttcctta gagtccaaga cacgaagagg attttcctcc aagcgacgtt ggctatcctt
      721 agacaaggtc tccttgagcg gtgtcaaata gtcaatcaag gcttggcggt aggctgcacg
      781 gctctcagga tttccaagag tgttgaggtg caatttgaca ccttgaatac cgatttcctt
      841 caaaaaatgg gctgccatag cgattgtttc cacatcggta gctggattgc tagagccaaa
      901 acactcaaca ccaatctggt ggaattggcg caagcgccct gcctgtggac gctcataacg
      961 gaacataggt cccatgtagt agaacttgct tggcttttgc acttctgggg cgaaaagttt
     1021 attttccaca taggaacgga caacgggtgc agttccttct ggacggaggg taatatgacg
     1081 gtcacccttg tcataaaaat cgtacatttc cttggttacg atatccgttg tatctccgac
     1141 agagcgactg ataacctcgt aatgctcaaa aataggcgtg cgcacttctg catagttgta
     1201 gcgtttgaaa atctcacggg caaagccctc aacgtactgc cacttagcag actcagcagg
     1261 taaaatatcc tgcgttcctt ttggtttttg taatttcata gggaatcctc tttaaactta
     1321 atagtcttat tttaccataa atagagggat taaaacagta agaaaaaaat taggatttag
     1381 atatcatttt tgagattaag aattgtcaaa aaaatagcta gcaaggaaag accaacaaat
     1441 agcatccaag tcaactgtat attccatacg gctactagtg aaaaacaagc tgttcccaca
     1501 ggtatggata aggtaaacaa tagacctaaa aaattactag tacgagctag aacctctgga
     1561 gctagatttt tcatgagcat ggcactaatc tttggttgaa ctttaccaga cacatacaga
     1621 gtaaagaaga gaaatagcaa accaagcacg acttgattga ataaattagc caaaccaact
     1681 agactaagtc ctacggtctc ccacatcatc aatctaggca aggactgctt cccaaaataa
     1741 tcattgcccg taaggctact gatgatgact gatactaaaa cacagaattg attgataaat
     1801 agtgcctctg tataagaaaa attcaagaga gaatggctca aaaagaagat attataaatt
     1861 ccacccaaag cgccacccaa ggaattaata agcaagacag caaagagcat aaaaccaaag
     1921 tttttctgtc cacttttaag aaaaacgaga cgtaaatttc ggtaaattgt taggaactgg
     1981 tctttgatag aaagcttctc attttttaag ttttcaccat cagcagatga cattgacagg
     2041 ctcaatttgc tttttcctaa aaagaggata gtggctgata ctaggaaaaa gcaggcattg
     2101 attcccgcaa cgagagaaaa attgttgacc gatagagcta agagccagac tccgaaagct
     2161 tgaccaccaa tagctgaaat ataggtgatg aactgtgaaa aagaataagc ctccatcaga
     2221 tcatcttcag ctactttttc cttaataaga ggcatacgca ggccacctgc aaaatcactg
     2281 atgatatcac taatgacatt gatcaaacac aggctagaaa aggcaaagag actagcttgc
     2341 tgaacaacta gggctgctag aaaaaataga accgcctgaa acaaaccgct atagaccatc
     2401 catttgacct tgtccctcgt gtaatctgcc cgaatccctg caaaaactgt aaagagggtc
     2461 ggaagaatca tgacaatatt cgccatagca acagcaaaag atgcttgtga caaggtcgat
     2521 gcatagacga taaagaccag gttgaaaatc gaaacaccaa aagcattgaa gaagcgtgat
     2581 aaagtcaaaa ttctataagc tggatttcta aacaatagtt tcatagataa tctccctcct
     2641 tgttctaagt tctacatcaa gaatagcttt agtatagcac ttatgaattt gcgaaacgat
     2701 tcttttgaat atatgcaaca aacaaaatga gcaaaaaaac gatagaactt ttgtaatgac
     2761 ctgagagagg gcaacagttc tatcgcttca aattttttct tggtttgcag atattcaaga
     2821 atcgggagtt tttctatagt attcggcaga tttattacag ccaagcatct caaaaatacg
     2881 gacagcatcc tccatctttt tctggccttc cttgactcta ccttgcttgc tatcaaggag
     2941 accttctgcc cacagataaa caattcggaa ataggtctca ttttccttgt agaaatgctc
     3001 ttcgataaca cgtttaaaat aataggcatt ggtaaattct tcacactcaa tactagctaa
     3061 aaagccattc aatagtatag tatgaaaaag gtttcgattg ccagacattt ccattagaaa
     3121 atcggattta cgtaccattt ctcgtacata tctagtaaaa agagaaacag ataaaaatgg
     3181 agaactgact gaaaataaat tgagttcata gattccccag atctcggtag aaaacaaata
     3241 atcatgaagg acttttcctt cctctgctgt taagtctacc ctttcatcta tgctcttcat
     3301 ataagacttg ataataatgg catttagaat atgtttctgt ttgttgtgag aatgggcatg
     3361 cttttatact ccctgcgata taagtcctca agaggtgcta tattctttgg ttccaagaca
     3421 tctgtaattt cttttctcaa ctcagaatct gtatcatact ggaaacctct tgccagaaag
     3481 aggatctcct ccacactggc agatatattt tccagagcaa atagaaactt ttccaccgaa
     3541 agctcactct gacctgtttc aaaacgggac aacatagacg gcgaaaattg tcctccggtt
     3601 gcttgtctca gtgagatatt tcttgactct cgtaattgtc taaagacttt tccaatctgc
     3661 tccatagact tccccttgat tccgtatttt cttcatttta tcatattttt cagaaaattc
     3721 atcaaaaact tgccaaattg tcagaattat gagaaaatag aggatattta tcacgtggag
     3781 ggactgctat gagagacgat atcaaaatca atgaccgtgc tttggccttg caagaccaaa
     3841 ttatcgaaaa actagagaaa gtttttgata cagatgtgga attggatgtt tacaatctag
     3901 gtctgattta tgaaatcaat ctggatgaaa cggggctctg caagattgtc atgaccttca
     3961 ccgatactgc ctgtgattgc gccgaaagcc tgcctattga aatcgtggca ggtctgaaac
     4021 aaatcgaggg tatcaaagat atcaaggttg aagttacctg gtcgcctgct tggaaaatca
     4081 cacgaatcag tcgctatggc cgtattgccc ttggactacc acctcgttaa gcagaccaat
     4141 cacttttaaa gatgaaaaaa gcaagccgaa aatggcttgc tttttgatac tcaatgaaaa
     4201 tcaaagggca aactagaaaa ctagccgcag gttgctcaaa acactgtttt gaagtt
//
LOCUS       DAVBIC010000086         4239 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.086, whole genome shotgun sequence.
ACCESSION   DAVBIC010000086 DAVBIC010000000
VERSION     DAVBIC010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4239)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4239)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4239
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.086"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            <1..1261
                     /locus_tag="VQ664_002056"
     rRNA            <1..1261
                     /locus_tag="VQ664_002056"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            1313..1385
                     /locus_tag="VQ664_002057"
     tRNA            1313..1385
                     /locus_tag="VQ664_002057"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1346..1348,aa:Ala,seq:tgc)
     gene            1510..>4239
                     /locus_tag="VQ664_002058"
     rRNA            1510..>4239
                     /locus_tag="VQ664_002058"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT         1157 a          884 c         1271 g          927 t
ORIGIN      
        1 atacatagcc gacctgagag ggtgatcggc cacactggga ctgagacacg gcccagactc
       61 ctacgggagg cagcagtagg gaatcttcgg caatggacgg aagtctgacc gagcaacgcc
      121 gcgtgagtga agaaggtttt cggatcgtaa agctctgttg taagagaaga acgagtgtga
      181 gagtggaaag ttcacactgt gacggtatct taccagaaag ggacggctaa ctacgtgcca
      241 gcagccgcgg taatacgtag gtcccgagcg ttgtccggat ttattgggcg taaagcgagc
      301 gcaggcggtt agataagtct gaagttaaag gctgtggctt aaccatagta ggctttggaa
      361 actgtttaac ttgagtgcaa gaggggagag tggaattcca tgtgtagcgg tgaaatgcgt
      421 agatatatgg aggaacaccg gtggcgaaag cggctctctg gcttgtaact gacgctgagg
      481 ctcgaaagcg tggggagcaa acaggattag ataccctggt agtccacgct gtaaacgatg
      541 agtgctaggt gttagaccct ttccggggtt tagtgccgta gctaacgcat taagcactcc
      601 gcctggggag tacgaccgca aggttgaaac tcaaaggaat tgacgggggc ccgcacaagc
      661 ggtggagcat gtggtttaat tcgaagcaac gcgaagaacc ttaccaggtc ttgacatccc
      721 tctgaccgct ctagagatag agttttcctt cgggacagag gtgacaggtg gtgcatggtt
      781 gtcgtcagct cgtgtcgtga gatgttgggt taagtcccgc aacgagcgca acccctattg
      841 ttagttgcca tcatttagtt gggcactcta gcgagactgc cggtaataaa ccggaggaag
      901 gtggggatga cgtcaaatca tcatgcccct tatgacctgg gctacacacg tgctacaatg
      961 gctggtacaa cgagtcgcaa gccggtgacg gcaagctaat ctcttaaagc cagtctcagt
     1021 tcggattgta ggctgcaact cgcctacatg aagtcggaat cgctagtaat cgcggatcag
     1081 cacgccgcgg tgaatacgtt cccgggcctt gtacacaccg cccgtcacac cacgagagtt
     1141 tgtaacaccc gaagtcggtg aggtaaccgt aaggagccag ccgcctaagg tgggatagat
     1201 gattggggtg aagtcgtaac aaggtagccg tatcggaagg tgcggctgga tcacctcctt
     1261 tctaaggata aggaactgcg cattggtctt gtttagtctt gagaggtctt gtggggcctt
     1321 agctcagctg ggagagcgcc tgctttgcac gcaggaggtc agcggttcga tcccgctagg
     1381 ctccattggt gagagatcac caagtaatgc acattgaaaa ttgaatatct atatcaaata
     1441 gtaacaagaa aataaaccga aaacgctgta gtattaataa gagtttatga ctgaaaggtc
     1501 agaaaataag gttaagttaa taagggcgca cggtggatgc cttggcacta ggagccgacg
     1561 aaggacgtga caaacgacga tatgccttgg gtagctgtaa gtaagcgatg atccagggat
     1621 ttccgaatgg gggaacccaa caggtagtac ctgttaccca catctgttaa ggatgtgagg
     1681 aggaagacgc agtgaactga aacatctaag tagctgcagg aagagaaagc aaaagcgatt
     1741 gccttagtag cggcgagcga aacggcagga gggcaaaccg aagagtttac tcttcggggt
     1801 tgtaggactg caatgtggac tcaaagatta tagaagaatg atttgggaag atcagccaaa
     1861 gagagtaata gcctcgtatt taaaatagtc tttgtaccta gcagtatcct gagtacggcg
     1921 ggacacgtga aatcccgtcg gaatctggga ggaccatctc ccaaccctaa atactcccta
     1981 gtgaccgata gtgaaccagt accgtgaggg aaaggtgaaa agcaccccgg gaggggagtg
     2041 aaatagaacc tgaaaccgtg tgcctacaac aagttcgagc ccgttaatgg gtgagagcgt
     2101 gccttttgta gaatgaaccg gcgagttacg ttatgatgcg aggttaagtt gaagagacgg
     2161 agccgtaggg aaaccgagtc tgaatagggc gccttagtat catgacgtag acccgaaacc
     2221 atgtgaccta cccatgagca ggttgaaggt gcggtaagac gcactggagg accgaaccag
     2281 ggcacgttga aaagtgcttg gatgacttgt gggtagcgga gaaattccaa acgaacttgg
     2341 agatagctgg ttctctccga aatagcttta gggctagcgt cgacattaga gattcttgga
     2401 ggtagagcac tgtttgggtg aggggtccat cccggattac caatctcaga taaactccga
     2461 atgccaatga attatggtcg gcagtcagac tgcgagtgct aagatccgta gtcgaaaggg
     2521 aaacagccca gaccaccagc taaggtccca aaataattgt taagtggaaa aggatgtggg
     2581 gttgcacaga caactaggat gttagcttag aagcagctat tcattcaaag agtgcgtaat
     2641 agctcactag tcgagtgacc ctgcgccgaa aatgtaccgg ggctaaaaca atttaccgaa
     2701 gctgtggata cctttatagg tatggtagga gagcgttcta tgtgtgatga aggtataccg
     2761 tgaggagtgc tggaacgcat agaagtgaga atgccggtat gagtagcgaa agacaggtga
     2821 gaatcctgtc caccgtaaga ctaaggtttc caggggaagg ctcgtccgcc ctgggttagt
     2881 cgggacctaa ggagagaccg aaaggtgtat ccgatggaca acaggttgat attcctgtac
     2941 tagagtatgt agtgatggag ggacgcagta ggctaactaa agcagacgat tggaagagtc
     3001 tgtctaagca gtgaggtgtg atatgagtca aatgcttata tctgtaacat tgagctgtga
     3061 tggggagcga agtttagtag cgaagttagt gacgtcacac tgccaagaaa agcttctagc
     3121 gtttaaacat actctacccg taccgcaaac cgacacaggt agtcgaggcg agtagcctca
     3181 ggtgagcgag agaactctcg ttaaggaact cggcaaaatg accccgtaac ttcgggagaa
     3241 ggggtgctga ctttaagtca gccgcagtga ataggcccaa gcaactgttt atcaaaaaca
     3301 cagctctctg ctaaatcgta agatgatgta tagggggtga cgcctgcccg gtgctggaag
     3361 gttaagagga gtgcttagcg taagcgaagg tatgaattga agccccagta aacggcggcc
     3421 gtaactataa cggtcctaag gtagcgaaat tccttgtcgg gtaagttccg acccgcacga
     3481 aaggcgtaat gatttgggca ctgtctcaac gagagactcg gtgaaatttt agtacctgtg
     3541 aagatgcagg ttacccgcga caggacggaa agaccccatg gagctttact gcagtttgat
     3601 attgagtgtc tgtaccacat gtacaggata ggtaggagtc taagagatcg ggacgccagt
     3661 ttcgaaggag acgctgttgg gatactaccc ttgtgttatg gccactctaa cccagatagg
     3721 tgatccctat cggagacagt gtctgacggg cagtttgact ggggcggtcg cctcctaaaa
     3781 ggtaacggag gcgcccaaag gttccctcag aatggttgga aatcattcgc agagtgtaaa
     3841 ggtataaggg agcttgactg cgagagctac aactcgagca gggacgaaag tcgggcttag
     3901 tgatccggtg gttccgtatg gaagggccat cgctcaacgg ataaaagcta ccctggggat
     3961 aacaggctta tctcccccaa gagttcacat cgacggggag gtttggcacc tcgatgtcgg
     4021 ctcgtcgcat cctggggctg tagtcggtcc caagggttgg gctgttcgcc cattaaagcg
     4081 gcacgcgagc tgggttcaga acgtcgtgag acagttcggt ccctatccgt cgcgggcgta
     4141 ggaaatttga gaggatctgc tcctagtacg agaggaccag agtggactta ccgctggtgt
     4201 accagttgtc ttgccaaagg catcgctggg tagctatgt
//
LOCUS       DAVBIC010000087         4116 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.087, whole genome shotgun sequence.
ACCESSION   DAVBIC010000087 DAVBIC010000000
VERSION     DAVBIC010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4116)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4116)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4116
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.087"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            <1..776
                     /locus_tag="VQ664_002059"
     CDS             <1..776
                     /locus_tag="VQ664_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000603792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2790151.1"
                     /translation="DYSIVEEKLDWQSKLSKIYPNVEFIKIEKLKLILLCKYRNQIID
                     LEDDKKRLLLLKLLYLTSKQFCYDEFKGAKFGCMSFFSHYQGYMSRLDSLDSDKFVSV
                     KQRIVSSISKLVEQYSDHIINLDRTLVDSLSDTLENQLFDDWDYILSEITTYSELLAK
                     SGLLYNSLDYKIDNVKKEVAKLSDFHQSLFKIEGFSDFFDSWQFQRYRSLVNQVYEIF
                     SMLQVSSVERTVLCGALSTIVFSKSNFNYQAFFEYIKDT"
     gene            805..1713
                     /locus_tag="VQ664_002060"
     CDS             805..1713
                     /locus_tag="VQ664_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000386786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2790152.1"
                     /translation="MDYVDVILDEYGSVFLIKDHIKLKINNLELYRYFSSFGMSHLQF
                     RKEELPGKLKQFDFEKNKSDSYFSKKSSLIDFIKRNYFYDIKLYSDNPKNPIESWKNK
                     TEKIKIAKSTEILWSEVANFSSISKSPYYCLLYNLKNTENYILIISKTYFSAIQKMVS
                     YNLNNYFELEDVCCKSIVSKRELIENSININKSKMKLLNVCEGSKGYTRRVFKYNNIF
                     VGQLEFHSNIIFSEIALNELSIVKLLDSVESVLSEQLFGKLNWDNLFVVLSDDFNDYL
                     DINESQKYYSNGSLRGLELGIFMGGV"
     gene            1715..3613
                     /locus_tag="VQ664_002061"
     CDS             1715..3613
                     /locus_tag="VQ664_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcaO-like family protein"
                     /protein_id="HET2790153.1"
                     /translation="MRIIEIVDVEDQLLQLLSAHTNIDIRAQELSTLDPDSKVDLIIY
                     LKSRRDIENINNIIIKSPNRNIIVIISAFDIIYALYFPKSTFRPCLNCLLLKLKDNNP
                     EHNLLLFLKYGTLPSKHFNLDNRLKSNLILFNEKLDPKVEEYSIEGVNTTNFTFHFSC
                     SCENSGYDMSERMADILLGEGKKLSPKNYRLKKSEHLFDFTRYLDRNFGFFHHSYDEK
                     ISEYAPLHAVEINVDAGYESGWGRTFMTEAATKSAFLESLERYCNSRNRRYKKLIRGC
                     FSDLSKKYNTLNPVDFCLSNKEYRDSSYKFHDFDSEKNYDWIFGKNITTGKICLLPSQ
                     LVFYKDFSKSEENERFVYETSNGCALGSSIEEAIFYGILEIIERDNFLLTWYLKEEVK
                     QLSWESLPSRLRIINERLKEDNCELKLFNITKEVGIPVIWALYINHNENASIRSFSAA
                     GCHINPLSAIESAIFEVITSVPTFERLIEVRNKESFIEEIQNNFSLIRDIDDHILYHA
                     HADYKNKMPFLFKNNYSEYQNEFDENRIFNTYSHATLTSDLQALIKIIEKKFGDIYVV
                     NISDKVSEKFGLYCVKVLIPGLLNMSFGHSNRRVNIERIKNYVDYRGGNVNSITLNSI
                     NHLPHPFP"
     gene            3637..>4116
                     /locus_tag="VQ664_002062"
     CDS             3637..>4116
                     /locus_tag="VQ664_002062"
                     /inference="COORDINATES: protein motif:HMM:NF025394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiopeptide-type bacteriocin biosynthesis
                     protein"
                     /protein_id="HET2790154.1"
                     /translation="MKRDWKSKHLFYHDVQQFDKLVIYLSKFMDKLVNQNQIEKYFYI
                     RYWEGGPHIRLRYLVRDTQNFETIDSMINKYAYKFWENNPPMKLLNKTDYKKIYNESI
                     DNNGKMDRKLRKNATIENIAYIPEIERYGGEEALIVSEDLFCICSQVSTALLNVVDNY
                     "
BASE COUNT         1540 a          442 c          712 g         1422 t
ORIGIN      
        1 cagattactc aatagtggaa gaaaaattag attggcaaag taaattatct aaaatttatc
       61 cgaatgttga atttataaaa attgaaaaat taaaattgat tttgttgtgt aaatatagaa
      121 atcaaattat tgacttagag gatgataaaa aaagattgtt actattgaaa ttattatatt
      181 tgacttcaaa gcaattttgc tatgatgaat ttaaaggagc gaaatttgga tgtatgtcat
      241 ttttttcaca ttatcaaggt tatatgagca gattagattc actcgactca gataaatttg
      301 tttcggttaa acagaggatt gtttcctcta tttctaaatt agttgagcaa tattcagatc
      361 atattataaa tctggataga actttagttg attctctaag tgataccctt gagaatcagc
      421 tatttgatga ttgggattat atattaagcg aaataactac atatagcgaa ttattagcaa
      481 aatcaggatt gttatataat tcgctagact ataagattga taatgtaaaa aaagaagtgg
      541 ccaagctaag tgactttcac caatctttat ttaaaattga aggattttca gatttttttg
      601 atagttggca atttcaaaga tataggtctc tcgtgaacca agtttatgaa attttttcaa
      661 tgttacaagt aagtagtgta gaaagaactg tgttgtgcgg agctctaagt actattgtct
      721 ttagtaagtc aaattttaac tatcaagctt tttttgagta tataaaagat acgtagaatt
      781 cgattttaaa ggaggctgaa atatatggat tatgtagatg taatattgga tgagtatggg
      841 agtgtttttc tgataaagga tcacataaaa ctaaaaatta ataatctaga actatatcgg
      901 tattttagta gctttggaat gagtcatctt caatttagaa aagaagagct tccaggaaaa
      961 ttaaagcagt ttgattttga aaaaaataaa agtgacagtt atttttctaa gaaaagtagt
     1021 ctgattgatt ttattaagag aaattatttt tatgatatta agttatattc tgataatccg
     1081 aaaaatccga tagagtcttg gaaaaataag acagaaaaaa ttaagattgc taaaagtaca
     1141 gaaattcttt ggagtgaagt agcaaatttt tcgtcaattt ctaaatctcc ttactattgc
     1201 ttgttatata atttaaagaa tactgaaaat tacatattga taatcagtaa gacatatttt
     1261 tcagccatcc aaaaaatggt ttcgtataat ctaaataatt attttgaatt agaagatgtt
     1321 tgttgtaaaa gcatagtgag caagcgagaa ttgatagaaa attcaattaa tattaacaaa
     1381 agcaaaatga aactgctaaa tgtttgcgaa ggtagtaaag gttacacaag aagagtattt
     1441 aagtacaata atatttttgt gggacaattg gaatttcact ctaacataat cttttcagaa
     1501 attgctttaa atgaattaag tattgttaag cttttagatt ctgttgaaag tgttttatct
     1561 gagcaactat ttggaaaatt aaattgggat aatttatttg ttgttttatc agatgatttt
     1621 aatgattatc tggatataaa tgaatctcaa aaatactact caaatggttc tttgagagga
     1681 ctggagcttg gaatctttat gggaggggtt taaaatgaga ataattgaaa ttgttgatgt
     1741 tgaggaccaa cttttacaac ttttaagtgc acataccaat attgatatta gagcacaaga
     1801 gttatcaaca cttgacccag attcaaaagt tgatttgatc atatacttga aatctcgacg
     1861 tgatattgaa aacataaata atattattat taaatcacct aacaggaata tcattgttat
     1921 aataagtgct tttgatatta tatatgcatt gtattttcca aaatcaacat ttagaccttg
     1981 tttgaactgt ctattattaa aacttaaaga taacaaccct gagcataatc tattattatt
     2041 cctgaaatac ggaacattac ctagtaaaca ttttaatctt gataataggt taaaatcaaa
     2101 tttaatacta tttaatgaga agttagaccc taaggtagag gagtatagta ttgagggggt
     2161 aaatactaca aattttactt tccattttag ttgtagctgt gaaaatagtg gttacgatat
     2221 gtcggaaaga atggcagata ttctacttgg tgaaggaaaa aaattatctc ctaaaaatta
     2281 tcgtttaaaa aagagtgagc atctattcga ttttactaga tatctagata gaaattttgg
     2341 attttttcat cattcatatg atgaaaaaat ctccgaatat gcgcctctcc atgcagtaga
     2401 gattaatgtt gatgctggtt acgagtcagg ctggggaagg acttttatga cagaggctgc
     2461 aacaaaatct gcttttttag agtcattaga gagatactgc aactctagaa atagacgcta
     2521 taaaaaatta attagagggt gtttttctga tttatctaaa aagtacaata cattaaatcc
     2581 tgttgatttt tgtctttcta ataaagaata tagagatagt tcctataaat ttcatgattt
     2641 tgattctgag aaaaattatg attggatatt tggtaaaaat ataactaccg gaaaaatttg
     2701 cttattgccc tcgcaactag tattttataa agactttagt aaaagcgaag aaaatgaaag
     2761 gtttgtttat gaaacatcaa atggatgtgc tttggggagt agtattgagg aagctatttt
     2821 ttatgggatt ttagagatta ttgaaagaga taatttttta cttacatggt atttaaaaga
     2881 agaagtaaaa caattatcat gggaatcttt accatctcgc ctacgtatta ttaatgaaag
     2941 actaaaagaa gataactgtg agctcaaact ttttaatata actaaagaag tgggcatacc
     3001 agtaatttgg gcattgtata taaatcataa tgaaaatgct agtattcgaa gtttttcagc
     3061 tgcaggctgt catattaatc ctttaagtgc aattgaatca gcaatttttg aagtaataac
     3121 ttctgtgcca acttttgaaa gattaattga agttagaaat aaagagtcat ttattgagga
     3181 aattcagaat aatttttctt taatacgaga tattgacgat catatattgt atcatgctca
     3241 tgcggattat aaaaataaaa tgcccttttt atttaaaaat aattatagtg aatatcaaaa
     3301 tgaatttgat gagaatagaa tttttaatac ttattcacat gcaacgctta catcagattt
     3361 acaggcacta ataaaaatta ttgaaaaaaa atttggagat atatatgtag tgaatataag
     3421 tgataaagtt tccgaaaaat ttggacttta ttgtgttaaa gtgttgattc ctggacttct
     3481 taatatgtca tttggacatt caaatcggcg tgtaaatata gagaggataa aaaattatgt
     3541 agattataga gggggaaatg taaatagtat tacattgaat tccataaacc atcttcccca
     3601 tccatttcca taagattata tataaaggaa taataaatga aaagagattg gaaatcaaag
     3661 catttatttt atcatgatgt tcaacaattt gataaattgg taatctattt atcaaaattt
     3721 atggataaat tagttaatca gaatcagatt gaaaaatatt tctatattcg ttattgggaa
     3781 ggggggcctc atattcgatt aagatatttg gtgagggata cacaaaattt tgaaacaatt
     3841 gatagtatga taaataagta tgcttataaa ttttgggaaa ataatcctcc aatgaagtta
     3901 ttaaataaga ccgattataa gaaaatttat aatgagagta ttgataacaa cggaaagatg
     3961 gatagaaaat tgaggaaaaa tgcgactatt gaaaacattg cctatatacc ggaaatagag
     4021 agatatggcg gggaagaagc tctgatagta agcgaagatc tattttgtat ctgtagtcag
     4081 gtttcaactg cgttacttaa tgtggtagat aactat
//
LOCUS       DAVBIC010000088         3321 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.088, whole genome shotgun sequence.
ACCESSION   DAVBIC010000088 DAVBIC010000000
VERSION     DAVBIC010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3321)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3321)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3321
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.088"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            complement(216..827)
                     /gene="rpsD"
                     /locus_tag="VQ664_002063"
     CDS             complement(216..827)
                     /gene="rpsD"
                     /locus_tag="VQ664_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HET2790155.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(1022..2074)
                     /locus_tag="VQ664_002064"
     CDS             complement(1022..2074)
                     /locus_tag="VQ664_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HET2790156.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVTKLEKGQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            complement(2071..2769)
                     /locus_tag="VQ664_002065"
     CDS             complement(2071..2769)
                     /locus_tag="VQ664_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2790157.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQT"
     gene            complement(2936..>3321)
                     /locus_tag="VQ664_002066"
     CDS             complement(2936..>3321)
                     /locus_tag="VQ664_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HET2790158.1"
                     /translation="GKPDLDNIVATKKVTININVKETSDTANGSLSPSNSGSGVTPMN
                     HNHATGTTDSMPADTMTSSTNTMAGENMAASANKMSDTMMSEDKAMLPNTGETQTSMA
                     SIGFLGLALAGLLGGLGLKNKKEEN"
BASE COUNT          924 a          743 c          638 g         1016 t
ORIGIN      
        1 ttttttacga aaatctattg aatatgccat aaaaggatta taccacattg tgtactattt
       61 ttggttcatt ttactatatc actttggact atatcggtct agttatgtct aaacgattat
      121 agctggatac taagagaaat caaaaaagca ctaagggaga acgtcccaaa gtgcttaata
      181 tcaaggcctc aaagcctgtc ttattcaata aaatattaca acatcttgtt gtagaattca
      241 acgacaagtg cttcgttgat ttctgggttg atttcgtcgc gttctggcaa gcgagtcaat
      301 gaaccttcca atttttcagc gtcgaatgat acgaatgctg gacgtccaag agtagcttct
      361 actgcttcaa ggattgctgg aactttcaat gatttttcac gaactgagat cacttgacct
      421 ggagttacgc ggtatgatgg gatatcaacg cgtttcccgt caacaaggat gtgaccgtgg
      481 tttacgaatt gacgagcttg acgacgagta gtcgcgagac caagacggta aacaacgtta
      541 tccaaacgac gttccaaaag aagcataaag ttgaaaccta ggattccgcc tttgattttt
      601 gtagcttgta cgaacaagtt acggaattgt ttttcaccta caccgtaagt gaaacgaagt
      661 ttttgttttt cagccaattg caaaccgtat tctgacaatt tagaacggtt gtttggtccg
      721 tgttgtcctg gtacgtagtt acgacgtgcc aattctttac ctgtacctgt aagtgaaagg
      781 ccaaggcgac gagcttgttt ccaagatggt cctgtataac gtgacatatg aatgtcctcc
      841 tgatataaat aatatttcgg tggaaatagt cacttagaaa gccctgattc gtgcagatgc
      901 ccttcgccta aacagccaag gttacttgtc ataagacacc tgttgacgag cttcatgctt
      961 tcctgctgat atttcacaca aaatccattt taccatgaat agctggattt gtaaaggggt
     1021 tttaggcttt attttcacta ccagagagat tgagaacgag ggtaaaggta cttcctagac
     1081 cgtactggct gctgactgtg atttccccac ccaattgatg ggccaattca cgcgcaatcg
     1141 caagtcctaa tccatgacca cctgtcttca tgttacgcga agtttcgaca cgataaaggc
     1201 gtttgaaaat attttccaaa tcctctgggg caatgccctg cccttcatcg gtcacactga
     1261 ttgaaagctg gcccttctcc agcttagtca ccacttccag cttggttcct ggagcagaat
     1321 atttaaaagc gttatcgacc agattcacca agatacgaga aagcttagca taatctccct
     1381 caatccgggc agactctggg attacctgca agtggacatc tcttctctcc tgctcaatca
     1441 aaaactgaaa ttcactcatg cactcaatta agagcttgtc cagaaaaata ctgtctttac
     1501 tggtagtttc cacctgattt ctagctgtgt ttagggtcaa aaaattcaac tcctcaacca
     1561 gtttattgag cctctccgtc tggcgtccaa tggttgctag ataatgagct tgctccgact
     1621 ccttgataat cccatccaaa atcccttcta ccgtcgcttg gatcgaagtg ataggggtct
     1681 taatatcatg cgacaactgg gcaatcatca agcccttttc tcgttcgctt tcttccaagg
     1741 aatcaaagct tacctgcaaa tcatgggaca tctcattaaa agtttgccct aattgctgaa
     1801 attctacagg accttgaacc tccaaatttg aaggaaaatc cttggccgct acccgcttgg
     1861 catgctcctt gagtttgccc aacgacgtaa agactggcaa taggagaaag agactaatcc
     1921 cagcaccgac aaggctggca acgatggtca tcccaagcaa aaagtaaatc tcgcctttcg
     1981 caatcagcat tttttgaaca gcccaaaaaa caaccaaaat ggttaagagg gttgaaataa
     2041 tatatccaac caaaatataa ctttttagtt tcatgtttgt cctctcggtt tctctatctt
     2101 atatcccaac ccccaaactg tcttaatagt gggcgtttgg tcactactat attttgccag
     2161 ctcctgtcga agagcatgga tatgcacatt caaggtattg gtgtcatcca cgtagtcttc
     2221 tttccagatc ttttcataga ggtctgtctt ggagaaaact cgctctggat tgctagctaa
     2281 aatccacagc aattcaaatg atttaacagt taaatccagc atttcttctc ctatttgaac
     2341 ttcatgacta ctatgattca tttttagatt gccaagggaa atcagctctg tttcgccccc
     2401 acgatgaagg cggcgcaaaa tattgtggac acgcaaaacc agctcacgtg ggctaaaagg
     2461 cttagcaata aaatcatctg ctcccaagct caggccgtaa atcttgtcct gttcactggt
     2521 cttagcagta ataaatagga aaggctgctc tggtgataag tattgaacct cactgattaa
     2581 atcataacca tccatccgag gcatcataac atctgtgata atcaaatcaa tcggtttttt
     2641 cttgaacagc tctagcgctt ccagtccatc atgggctacc aagacctgat aacctgcctg
     2701 aattaagtat ctctgatgaa tatctgtgat ttctacctcg tcgtcaacga gtaaaattgt
     2761 ctttcccatc tgtctctcct ttgataaaaa cagtgctata ctgctttaag tataacacta
     2821 tttttattgt tttacgatga ttttaatctg ctattgaaag aaagtcctga ttgctgattg
     2881 agttgttaaa ctaatcttag tcagcccact atccatcatt tatttcctta gctgattagt
     2941 tttcttcttt tttgtttttc aaacctagac caccgagtaa acctgcaagc gcaagcccaa
     3001 ggaaaccaat acttgccatt gatgtttgag tctcaccagt atttggtagc atagctttat
     3061 cctctgacat catcgtatca gacatcttgt tagcagaagc agccatgttt tcacctgcca
     3121 tcgtgttggt agaacttgtc atggtgtcag caggcatgct atctgtagta cctgtagcat
     3181 gattgtgatt catcggagtc acgccagaac cagagttaga aggtgataat gaaccatttg
     3241 ctgtgtctga tgtttcttta acatttatgt taatagtgac ttttttagtt gctacgatgt
     3301 tgtccaagtc tggtttaccg t
//
LOCUS       DAVBIC010000089         3052 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.089, whole genome shotgun sequence.
ACCESSION   DAVBIC010000089 DAVBIC010000000
VERSION     DAVBIC010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3052)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3052)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3052
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.089"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            complement(185..1660)
                     /locus_tag="VQ664_002067"
     CDS             complement(185..1660)
                     /locus_tag="VQ664_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HET2790159.1"
                     /translation="MKELDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTGKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSLLLIGEQMNPEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEEVIELSEYARHEINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDDSVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
     gene            2367..3052
                     /locus_tag="VQ664_002068"
                     /pseudo
     CDS             2367..3052
                     /locus_tag="VQ664_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
BASE COUNT          959 a          653 c          569 g          871 t
ORIGIN      
        1 aaagcattca gaatatacct accaactctt gacacgctac cctaatcctc agaaaaggat
       61 tgaggcagga tttgataagc tgatagaaat taagcgattg accgcttcta attcaagggc
      121 tttttgccgt gctctaaaat catcgccaaa tcatcaaatt gaaataagaa atagtttaga
      181 taaactattg acttttctta tagtttgtct ttctcttaat aacgttgata tgattgacct
      241 ctggatcttc cgtcccttgg agggagcaac cacgttcctt ggcgaattgg atatagtcga
      301 caatttctcg tgtaatgcgt tcaccaggag ccaagatagg aatacctgga gggtaacaca
      361 taacaaattc tccacagacc tgtccaacag aatcatccaa agttaaactt tttctttctg
      421 aatagaaggc ttcttgcgga gacagcacta actcgggctg aatatattct cctgctatca
      481 aatcttttcc atctcttgaa tagagtctct taatatcagc cagagcacca accaagcgct
      541 cgatgtcttg gatgcggtcg ccgatggaaa tataggccaa gatattgccg atatcaccaa
      601 actcgatctg aatgtcgtat tcgtctcgca agaggtcata aacctcgata cctgttaagc
      661 caataccctg agtgtaaact gacaacttag ttacgtcaaa atcgcaaacc gaaacaccgt
      721 ctattaactc ttttgagtag gcatagtagc caccgatagc attgatttca tgacgagcgt
      781 actcggatag ctcaatgact tcctcaaacg actctttacc acgaagggcc aagttgcgac
      841 gtgaaatatc caaactagcc atcaataagt aagaggcaga tgtagactgg gtcaggttta
      901 taatctgacg aacgtactcg ggattcatct gctccccgat taaaagaagc gaactttgtg
      961 tcaaactccc accagactta tgcatggaaa ctgctgccat atcagctcct gcatccatag
     1021 cagaaattgg aagtttacca gtgaaatgca aatgcgctcc atgggcttca tctactaaaa
     1081 ccatcatgcc agcttcatga gccatttctg tcaacccctt taggtctgaa cagatgccgt
     1141 agtaagtagg attgttgatt aggatagcct tagcatctgg atggtccttt atggcctgtg
     1201 ctactcggtc attttcaaga cctaaagcga taccaatctt aggatctaca ctcatctcga
     1261 tatagatggg aatggcacca catagaacca acgcattgat agcagattta tggacatttc
     1321 gtggcagaat aatcttatct cctgccttgc aggttgccag aatcatagtc tgcaccgatg
     1381 aagttgttcc accaatcatt agaaaggcat ggctagctcc aaaagcatct gcagccagct
     1441 cctctgcatc acgaataatc gaaataggat ggcctaaatt atccaagggt ttcatcgaat
     1501 tgacatcaat gcctacacat ttttctccta agagttcgac aagttctgga tttccccgtc
     1561 cacgcttgtg acctggaaca tcaaagggaa caatcctttt cttgcgtaac ttcaccaagg
     1621 cctcataaat tggggcttgg ttttgatcta actctttcaa aacatactcc tttcaatatt
     1681 tttaggacct tatgaaaact aaggaactaa aggttgactc atgaaaaaag agcaggtttt
     1741 cacctgctct gcaatcttct gacgtgttta ttttggtttc tgttgagtat gtctgttccc
     1801 gatgtttcct aactctctag tagcaaatat tacgtacttt attgatcgtt tcacaagatg
     1861 acgtgtgctt tcaccacact aaaaatttat gaattaggac aagtgtccta acatcaactt
     1921 ataaaagtag gcttttaacc ctatcaataa tgtggctttt caaccacgct tcggcattca
     1981 accctgcctg tccgtaggca ttttttactc gggtttatat ttgctagaaa acatcatctc
     2041 attttctaag ctttattact atatcatgtt tttaagaact tgtaaagtat tttttgataa
     2101 aaaacaaaaa tataatagat tgaaactaga atagtacacc tctgcttcta aaacattgtt
     2161 agaaatagat tttactgtcc tgatcgattt gttctgttct tgtttcattt tactatatgt
     2221 tcgtaaatga aagttctata atgaagttag ccacccagcc ctcctaaaaa ttagatggtt
     2281 caactagctg atagctcttg taggcataag aaaacacctc tgtgttatac ttgttgttca
     2341 accacaaaca caagaaaggc acagaaatgc aagacaatta tactacaaaa ggtaaacatt
     2401 tgacaatcga tagccgtcgc ttaatcgaaa gatggaaaaa agaaggaaaa tcaaatagag
     2461 aaattgcctc tctacttgga aaagctcctc aaactatcca cactaaaatc aagcgtagga
     2521 cagtccgaaa atgtcttgga aaagggcgct tcaaagaggt ttattctgcc gactatgctc
     2581 aacagtctta tgaaaataat cgcaagcact cggtcaagag atcaagcgtg accaaggaac
     2641 taaaggaaaa gattctccac tatcataacc aaaaattttt gcctgaaatg atggttatgg
     2701 ctaaaggggt taacgtggga atttcaacca tttactattg gattcatcat ggaaaattgg
     2761 ggtaaagcaa gcaggatctg ctttacccta gaaaaggaaa agtgcttaag aaacaggcca
     2821 gcaccaactt taaacctgct ggtcaatcca tcgaacagcg gcttgaagct atcaattttc
     2881 gcttggagaa tgggcattat gagattgata cggttctact tacgagagcg aaaaactact
     2941 gcttgcttgt cttgacggat cgaaaaagta gacatcagat catccgattg attccaaata
     3001 aaagtgctga ggtggtcaat caggctctaa aactcatctt aaaacaacac aa
//
LOCUS       DAVBIC010000090         3051 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.090, whole genome shotgun sequence.
ACCESSION   DAVBIC010000090 DAVBIC010000000
VERSION     DAVBIC010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3051)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3051)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3051
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.090"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            101..1078
                     /locus_tag="VQ664_002069"
     CDS             101..1078
                     /locus_tag="VQ664_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HET2790160.1"
                     /translation="MLKLGVIGTGAISHHFIEAAHTSGEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLADKQVLGADFNYAKYSSKMPDLLAG
                     QTPNVFSDRFAGGALMDLGIYPLYAAVRLFEKANDATYHAQQLDNSIDLNGDGILFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGNQVQLPIQQAPHT
                     MTEEVAAFAHMIQQPDLNLYQTWLYDAGSVHELLYTMRQTAGVRFEAEK"
     gene            1075..2157
                     /locus_tag="VQ664_002070"
     CDS             1075..2157
                     /locus_tag="VQ664_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET2790161.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFELLLAGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYMSATTKFDQEKIVPNTRTIDLSDQKLDNIQHFYMQVDQRHRVD
                     MLRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILAVSLASDVNVKFRKIILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRMGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
     gene            complement(2221..3051)
                     /locus_tag="VQ664_002071"
                     /pseudo
     CDS             complement(2221..3051)
                     /locus_tag="VQ664_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT          942 a          683 c          546 g          880 t
ORIGIN      
        1 aaagctaata gcttatttga aattttctcc tctctgttgg atagtcccgt ctatctatgt
       61 tataatgaaa gaaggattta aaatcggaaa aggagtattt atgctaaaat taggtgtcat
      121 cggaactggc gctatcagcc atcatttcat agaagcagcc cataccagtg gagaatacca
      181 actggtcgca atctattcta gaaaactaga aactgcagca acctttgctt ctcgctatca
      241 gaatatccaa ctattcgatc aattagaagt cttcttcaaa tcttcttttg atttagtcta
      301 tatcgccagt ccaaactcct tacattttgc tcaggcaaaa gctgccttgt ctgctggtaa
      361 acatgttatt cttgaaaagc cagctgtcac tcaaccacaa gaatggtttg atttgattca
      421 aacagctgaa aaaaataact gttttatctt tgaagcagct cgtaattatc acgagaaagc
      481 ctttactact atcaaaaact ttttagcaga taagcaagtg ttaggagcag atttcaacta
      541 tgccaaatac tcttccaaga tgcctgactt attggctgga caaacaccaa atgtcttttc
      601 agaccgtttt gctggtggag ccctcatgga tttggggatt tatcccctct atgctgctgt
      661 tcgtcttttt gaaaaagcta atgacgcgac ttaccatgct caacagcttg acaatagcat
      721 tgacctaaat ggagatggta tcctcttcta cccagactat caagttcaca tcaaggctgg
      781 aaaaaacatc acttccaatc ttccttgcga gatttataca acagatggaa ccttgactct
      841 caacacgatt gagcatattc gctcagctat ttttaccgac caccaaggaa atcaagtcca
      901 gcttcctatc caacaggctc ctcatacgat gactgaggaa gtcgctgcat ttgcacacat
      961 gatccagcaa ccagatctga atctctacca aacttggctg tatgatgcag gctctgttca
     1021 tgagctacta tataccatgc gccagactgc tggcgttaga tttgaggcag aaaaatgaaa
     1081 accaaactac cgactgaatg gcaagaactg agtgaccaac tcggtttcca agaattcacc
     1141 cccattcaaa ctcaactatt tgagctcctt cttgctggag aaaacctcct aggagtgagc
     1201 caaaccggaa ctggtaagac cctagcgtat ctcctaccaa gtcttctcag actacaaaag
     1261 aaaaaagccc aacaactctt gattctagca ccaaacacgg aacttgctgg acagattttt
     1321 gatgtatgta aaacgtgggc agaagctatc ggattgactg ctcaactctt cctttcaggt
     1381 tcaagtcaga aacgacaaat tgaacgtctt aaaaaggggc cagaaattct gattggaact
     1441 cctggccgta tctttgaact cattaaactt aaaaaaatca agatgatgaa tgtggaaacc
     1501 atcatcctgg atgaatttga ccaattacta gatgattctc agattcactt tgtagagaaa
     1561 atcactcact acgcacctcg tgaccaccaa ctggtctaca tgagtgccac gaccaagttt
     1621 gaccaagaaa agattgtgcc gaatacacgc actattgatc tctctgatca aaaattggac
     1681 aatatccagc atttctacat gcaggtagac caacgtcatc gagtggatat gctacgaaaa
     1741 ctggctcatg tagaggattt ccgtggtcta gtcttcttca atagcctgtc agaccttggg
     1801 aatgccgagg aaaaactaca gtatcgtgat atattggctg tttccctcgc tagtgatgtt
     1861 aatgttaaat ttagaaaaat catcttagaa aagtttaaag ataaccaact aaccctgctt
     1921 cttgcaactg accttttggc tcgtggaatt gatatcgata gcctagaatg tgtcgtaaac
     1981 tttgatattc ctagagatag cgaaacctac acacaccgtg ctggccgtac tggtcgtatg
     2041 ggcaaggaag gttatgttat cactctcgtc actcatccag aagaaatcaa aaaacttaaa
     2101 aagtttgcaa gtatccgaga aattgtccta aaaaaccaag aactctatat caaataaagc
     2161 cccattgctc tatacacatc cagtgtatgg agctttttta taagcaattc aattttatac
     2221 tcatctgctt tcaaaaagca ttctagtcca tctccgatta acgatggact ttatcacctc
     2281 cttctccaat ccttgtatga catcttgaag ttgattcatg acatcttcca aaattcgaaa
     2341 ggctttattc ttaaatccac gtttacgaat ctctttccac acttgttcaa tggggttcat
     2401 ctctggtgtg tatggaggaa taaatgcaaa accaatatta gtcggaatct ttaagatact
     2461 tgatttatgc catatagcat tgtccataac gagtaaaaaa taatcatctg gataagcttg
     2521 tgaaagcttt tctaaaaagg cgttcatcca ctcagtatta catctaccag ctattaagaa
     2581 aaatgattcg cctgtatggg catcaacagc tccataacaa tagcgaaatt ctcgtatata
     2641 gtgactatgg atatgtggac ctactcctat tggagcccaa caagatccca gtttactgat
     2701 tctaccgaaa ccagcctcat cttggtacat caagcgaacc ttacgaaaac gtctactata
     2761 tttaaaacgc tttcttgtct tcttgaattg agattttatt tttagacgcg acaatggttt
     2821 gagcgtctgc tttcttagga tgttctggac gtggcataat atttcgccaa ccatggcgct
     2881 tcaacagttg atagaaggca tcacgtgtgt aggaacgacc taactccttt ttataagcct
     2941 gaaataaggc atcaattgta acaaattctc ctgcctctgc agccttcaaa tggcgggcaa
     3001 gaaagacttt ctcttcctca actgtcatat atgcatggtt acgaccacca c
//
LOCUS       DAVBIC010000091         2986 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.091, whole genome shotgun sequence.
ACCESSION   DAVBIC010000091 DAVBIC010000000
VERSION     DAVBIC010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2986)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2986)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2986
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.091"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            complement(481..1206)
                     /locus_tag="VQ664_002072"
     CDS             complement(481..1206)
                     /locus_tag="VQ664_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2790162.1"
                     /translation="MKLLKNELIKSKIFLFIIVDICIQILVILAIKTYILDISAPYSE
                     LDYNKYWYVLHALIYMPMIFPIQILYQNLREALIEDNNNGWNIMVINTNNLVKIIYIK
                     VTINIVRCFICYFVYTIFSLIQLGGMGTDMLLTNIIFPNIIFPNIMSFLLFLPIAIFM
                     QICCIRFDSILAKALPNILLILIVLITFQSDWNIFIPATYYYTEIQSTTNLGIKLLVC
                     IWIMGFEFSLLPKLIKLKEQNLV"
     gene            complement(1219..1956)
                     /locus_tag="VQ664_002073"
     CDS             complement(1219..1956)
                     /locus_tag="VQ664_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2790163.1"
                     /translation="MIKLEFLKQKKSILWFVLIFPIILNALLYIDLTFRYRGYLLVHQ
                     NELALSNWQLIFKEQTIFYFSELFYLVLSLIIYEVFAVEFKNDAWLTVISLPFRNKYT
                     INSKLLITVVYTFTFWLSDYISLYVIGKAIDNSLEIGLIFFLKTFTIQLISSLMIMLL
                     YFLTLVLIRKISGIIPIGIIMMILTISIYYNDYNFKIYLPFTYLSHAFRVTESQFYMI
                     LLSNIIIIVLFYILIRKLNERSFEMKL"
     gene            complement(1949..2677)
                     /locus_tag="VQ664_002074"
     CDS             complement(1949..2677)
                     /locus_tag="VQ664_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2790164.1"
                     /translation="MAIVEIINLTKSFKDIEVIHNTSFYLNKGKVYGFVGPNGAGKTT
                     IIKMILGILKPDSGKITIFNQTVEQNSKNILSRIGLVLGPSFYGHLDAYKNLKLIANM
                     KGLSLDTERLNEYLSMVGLKDVKKKKVKNFSMGMKQRLSIAASLLGSPEILIWDEPIN
                     GLDPQGVIEIRSLIRFLQEKKGITFLISSHILSELDKVISDIIIINYGKVEFFGSCHY
                     LLQKYNCRNLEEAYLACLAGGEYD"
     gene            complement(2711..2881)
                     /locus_tag="VQ664_002075"
     CDS             complement(2711..2881)
                     /locus_tag="VQ664_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2790165.1"
                     /translation="MKKVNEYVISTAASLGVMIGIVFAIFLDFPVEYGISLGLLNGIV
                     LGSLIVYKNNKN"
BASE COUNT         1121 a          467 c          351 g         1047 t
ORIGIN      
        1 tggacatttt gaactaaaat taatttatta aacatatctc ataagcatat ctattatagg
       61 tgagacaata ttaagaaaga cggttaaaaa acaacctgac tccactggaa ttcaggaatc
      121 aggtcgctta agattttata ttattttact gtctacttga cagggagctg ttcaccaatg
      181 ggaatctata gctttttttg tgactgagaa ctattttatc tcagacttct tcaacacacc
      241 ttattattgg gcacttacgg aaggttaatg aattatttaa aataaaagta aagagaagca
      301 aacagacact ctatagctgt tagacgcttt ttagagtaat aacaatttga taaagtgaat
      361 acaacttgct taattaagcg taagaaacca gaatcataaa atcaattact ttgaagtcat
      421 gactcacgtt gtattgtttc attgttaatc gtattcaatt atttaatttt cgagcaacat
      481 ttaaactaga ttttgttctt tcaattttat tagttttgga agaagggaaa attcaaatcc
      541 cataatccag atacaaacta ataatttaat acctaagttt gtagttgact gaatttctgt
      601 ataataataa gttgcaggta taaatatatt ccaatcactc tgaaacgtga ttaaaacaat
      661 aagtatcagc aaaatattag gtaaggcctt tgctaaaatg gaatcaaatc ttatacagca
      721 aatttgcata aagatagcta taggtaaaaa taacagaaat gacattatat tgggaaatat
      781 tatattggga aatattatat tggttaataa catatcagtt cccataccac ctaattgaat
      841 taaagaaaaa attgtataaa caaaataaca aataaaacat ctcacgatat ttatcgttac
      901 ttttatatag atgattttca cgagattatt agtgttaatc accatgatat tccaaccatt
      961 attattatct tcaatcaatg cctctcttag attttgatac aaaatttgta taggaaaaat
     1021 cattggcata tatattaaag cgtgtaaaac ataccaatac ttattataat caagctctga
     1081 gtatggtgcc gaaatatcta aaatatatgt ttttatagct agaatgacta gaatctgaat
     1141 acagatgtca acaataataa ataaaaatat tttactctta atcaattcat ttttaagtaa
     1201 cttcattttt attacctatt aaagtttcat ctcaaaactt ctttcgttca atttacgaat
     1261 taatatataa aaaagtacga tgattattat attagatagt aaaatcatat aaaattgact
     1321 ttcagtcact ctaaaagcat gagaaagata agtaaatggt aagtaaatct taaaattata
     1381 atcgttgtag tatatgctaa ttgttaaaat catcattata ataccaattg gtattattcc
     1441 agaaattttc cttataagta ctaaagttag aaaatataat aacattatca tcaacgagga
     1501 aattaattga atggtaaatg tttttaaaaa gaaaatcaaa ccaatctcta aactgttatc
     1561 aatagccttc ccaataacgt ataagctaat ataatcagac aaccaaaaag taaatgtgta
     1621 aaccactgta atgagtaatt tagaatttat tgtgtacttg tttctaaatg gcaatgaaat
     1681 tacggttaac catgcatcat ttttaaattc tactgcaaac acttcgtaaa ttattaaaga
     1741 tagaactaaa taaaatagtt cagaaaaata aaatattgtt tgttctttaa aaattaactg
     1801 ccaattagat aaagcaagtt cattttgatg caccaataaa taacctcgat acctaaaagt
     1861 taagtctata tataacaaag cattcagaat tattggaaaa ataagaacaa accataagat
     1921 gctttttttc tgctttagaa actctaattt aatcatattc acctccagct aaacaagcta
     1981 agtaggcttc ttccagattt cgacaattat acttttgtaa aaggtagtgg caagaaccaa
     2041 aaaattcaac tttcccataa tttataatta taatatcaga tatcacttta tccagttcac
     2101 taagaatatg acttgatatt aaaaatgtaa tacctttttt ctcctgtaga aaacggatta
     2161 aacttctaat ttcaattaca ccctgtggat caagtccatt gattggttca tcccaaatta
     2221 atatttctgg actacctaac aatgatgcag ctatacttag acgttgtttc atgcccattg
     2281 aaaaattttt cacttttttc tttttaacat cttttaatcc taccattgat agatattcat
     2341 taagtctttc agtatctaaa ctaagccctt tcatatttgc tattaacttc aaatttttat
     2401 aagcatcaag atgaccataa aatgaaggtc ccaaaactaa tcctatccta gataatatat
     2461 ttttggaatt ctgttctacg gtttgattaa aaatagttat tttcccagaa tctggtttta
     2521 aaatccctag aatcattttg ataattgtag tttttccagc cccatttggt ccaacaaaac
     2581 catatacttt tcccttattt aaataaaatg aagtgttatg aataacttca atatctttaa
     2641 agctttttgt tagatttata atttcaacta tagccatctc tactccttag tttacagcaa
     2701 aaaattatgc ttaattctta ttgtttttgt aaacaatcag cgaacccaat actattccat
     2761 tcaacaaacc taaagaaata ccatattcaa ctggaaaatc taaaaaaatt gcaaatacta
     2821 ttccaatcat cacccctagt gaggctgctg ttgaaattac atattcattt actttcttca
     2881 ttttctttac acctcatttc ctttttgtat ataagctgta gtactatcca ccaagatcca
     2941 ttaagtactt atgatttcct gactcaacaa tcttaccacc tttcat
//
LOCUS       DAVBIC010000092         2749 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.092, whole genome shotgun sequence.
ACCESSION   DAVBIC010000092 DAVBIC010000000
VERSION     DAVBIC010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2749)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2749)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2749
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.092"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            311..787
                     /locus_tag="VQ664_002076"
     CDS             311..787
                     /locus_tag="VQ664_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET2790166.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEQLFDQVATLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPDK
                     EVEVSLLFFIINNSSSSQTNILAQLMDFFTGNGHLEDLSKISEPEKLYAYIAEATA"
     gene            825..1130
                     /locus_tag="VQ664_002077"
     CDS             825..1130
                     /locus_tag="VQ664_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET2790167.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSAPVFDNIEAAIKEHGLS"
     gene            1178..2653
                     /locus_tag="VQ664_002078"
     CDS             1178..2653
                     /locus_tag="VQ664_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HET2790168.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNIVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLFIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLQGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVVFLVFYIGIFAWYRKQMIKRNEEYAAKAK"
BASE COUNT          838 a          520 c          534 g          857 t
ORIGIN      
        1 gatttttcaa tagacttcgt tattgggcgg ttacgatatg atcactgact tcgtcagtct
       61 tatctacaac ctcaaaactg tgttttgagc aacctgcggc tagcttccta gtttgctctt
      121 tgattttcat tgagtattag aacagaaaaa atacttggag tatttgtttg tgtgtttatt
      181 tttatataac aaactataaa caaaacaaaa atataaaaaa agagacaaaa aagaacagaa
      241 agcaattgac aacggtttca tatagtgtta tacttatggc ataaagttaa tggaaagaag
      301 ggaaaaactt atggtattag attatttctt tgacaaaaac cttgtgtttt gcttagaagc
      361 ggataatcaa gaacaactct ttgatcaggt tgcaacttta ttggaagaac gagaaattgt
      421 cactccaact tatcgtgaag ccttgatcac gcgtgaaaag tcatttccaa ctggtttaga
      481 tatggaattt ctaggaaagg acttgccaaa tgtagcgatt cctcatacag atattgttca
      541 taatctagct gagaaagtgg tggttgttcg attagaaaaa ccagtaactt ttcacaatat
      601 gatagctcct gataaggaag tagaagtatc cctactcttc tttattatta acaattcaag
      661 ttcaagtcaa acaaatattc tggctcagtt gatggacttt ttcacaggaa atggacatct
      721 tgaagaccta tcaaaaattt ccgaaccaga aaaactttat gcttacattg ctgaagcaac
      781 cgcttaatct tgtctattaa aaaataaaat cggaggaaat ccaaatgatt aaaattcttg
      841 ctgcctgcgg tgcaggtgtt aactcaagtc accaaattaa aagtgctcta gaagaagaac
      901 tttcaaaccg tggttatgat gttcactgtg atgcagtcat ggtgaaagat gtaaacgaag
      961 accttatgaa aggttacgat atctttacac caatcgctgc aacagacctt ggttttgaac
     1021 caggtatccc agttatcgaa gctgggccaa tcttattccg tatcccagca atgagcgctc
     1081 cagtatttga caatattgaa gcagctatta aagaacacgg attaagctaa ttctaatttg
     1141 ttaacattca tataacataa aaaagggagg aactgttatg gatgcaatct ttgacctaat
     1201 cggaaaggtt ttcaatccca ttttagaaat gggtggacct gtcatcatgt taatcatttt
     1261 gacagtattg gctttacttt ttggagtgaa attctccaaa gcgcttgaag gtggtatcaa
     1321 acttgccatc gctcttacag gtatcggtgc tatcatcggt atgctaaatg gtgctttctc
     1381 agcatcactt gcaaaattcg ttgaaaacac tggtatccaa ttgagtatta ccgacgttgg
     1441 ttgggcacca ctcgcaacaa tcacttgggg ttctgcttgg acactatact tcttgctcat
     1501 catgttgatt gtcaacatag tgatgctagc tatgaagaaa acagatacac ttgacgttga
     1561 tatctttgat atctggcact tgtctatcac aggtctcttg attaaatggt atgctgataa
     1621 caatggtgtg agtcaagggg tttcactctt tattgctaca gcagctatcg tccttgtcgg
     1681 tgtgttgaaa attatcaact ctgacttgat gaaacctaca tttgatgacc ttcttaacgc
     1741 cccaagttca tcaccaatga catcaactca catgaactac atgatgaacc cagttatcat
     1801 ggttttggat aagatttttg aaaaattctt cccaggcctt gataaatatg actttgatgc
     1861 tgctaaattg aacaagaaaa tcggtttctg gggatctaaa ttcttcatcg gtttcatcct
     1921 tggtatcgtt atcggtatta tgggaactcc acatccaatt gcaggtgttg cagatgcaga
     1981 taaatggcgt cttgttatca aaggatggtt gtctcttggt ttgactgccg gtgtatcttt
     2041 ggaactcttc tcacttatcg gttcatggtt catcgcagcc gtagaaccac tatcacaagg
     2101 tattacaaac gttgctacta aacgtcttca aggacgtaaa ttcaatatcg gtcttgactg
     2161 gccattcatc gctggtcgtg ctgaaatctg ggcttgtgcc aacgtacttg caccaatcat
     2221 gttgattgaa gcagtgcttc tttcaaaagt tggaaatggt atcttgccac ttgcaggtat
     2281 catcgctatg ggtgttactc cagctctctt ggttgtaact cgtggtaaat tgctccgtat
     2341 gattatcttc ggaacactct tgttgccact cttccttctt tcaggtacac ttattgcacc
     2401 atttgcaaca gaacttgcta aaggtgtagg tgccttccca gaaggtgtga gccaaactca
     2461 attgattact cactctactc ttgaaggacc aatcgaaaaa cttcttggtt ggacaattgg
     2521 taacactaca actggtgata tcaaagcaat ccttggtgca gtagtcttcc ttgtattcta
     2581 tatcggtatc tttgcttggt acagaaaaca aatgatcaaa cgtaacgaag agtacgcagc
     2641 aaaagcaaaa taatgcgctc ctataaaata taaactcaat gaaaatcaaa gagcaaacta
     2701 ggaaactagc cacaggttgc tcaaaacaca gttttgaggt tgtagataa
//
LOCUS       DAVBIC010000093         2549 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.093, whole genome shotgun sequence.
ACCESSION   DAVBIC010000093 DAVBIC010000000
VERSION     DAVBIC010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2549)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2549)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2549
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.093"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            368..1714
                     /gene="gdhA"
                     /locus_tag="VQ664_002079"
     CDS             368..1714
                     /gene="gdhA"
                     /locus_tag="VQ664_002079"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HET2790169.1"
                     /translation="MTSAKEYIQSVFETVKARNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVVSFRVPWVDRDGKIQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGTVWTYAGNYDIALPCATQNEINGEAAKR
                     LVAQGVICVSEGANMPSDLDAIKVYKENGIFYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDGRLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGIV"
     gene            complement(2220..2390)
                     /locus_tag="VQ664_002080"
     CDS             complement(2220..2390)
                     /locus_tag="VQ664_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2790170.1"
                     /translation="MKKENEYVILTIASLGVMIGIVFAIFLDFPVEYGISLGLLNGIV
                     LGSLIVYKNNKN"
     gene            complement(2403..>2549)
                     /locus_tag="VQ664_002081"
     CDS             complement(2403..>2549)
                     /locus_tag="VQ664_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2790171.1"
                     /translation="IIIAHRLSTIKDADIIFVMKGGKIVESGNHKYLITLGGEYYSLY
                     TKRK"
BASE COUNT          818 a          472 c          439 g          820 t
ORIGIN      
        1 ttggatttct tctttagttg atttcatatc actattatat aatgattttt gattttagtc
       61 tggtataaat attgctttcc tccaaaatgg tcataatttt actagcaaat ctaacatatc
      121 acggataaat taacaagtga tttctgaatt gctaaacatt ttcttttctt atagcatacc
      181 atactttaag attttgtctt tgagaaagat atttccaaga aaaacgttcg tttttttatc
      241 tattttcaaa aaaaccaaaa actgaattga aagaattttt agaaaatttc tgttttttct
      301 ttacagtgaa aaaaaattct gctataatgt cttatgtaat aaaatatgac aataaaagga
      361 gaacgatatg acatctgcta aagaatatat ccaaagcgtg tttgaaactg tgaaagctcg
      421 taacgggcac gaggctgaat tcctccaagc tgttgaagaa tttttcaaca ctttagaacc
      481 tgtatttgaa aaacaccctg agtatatcga agaaaatatc ttggcacgta ttactgagcc
      541 tgagcgcgtg gtttctttcc gtgttccttg ggttgaccgt gatggaaaaa ttcaagtaaa
      601 ccgtggttac cgtgttcaat tcaactcagc tgttggacca tacaaaggtg gacttcgttt
      661 ccacccaact gtaaaccaag ggatcttgaa attcctcgga tttgaacaaa tctttaaaaa
      721 tgtcttgact ggacttccta tcggtggagg taaaggtgga tcagacttcg atcctaaagg
      781 taaaacagat gctgaagtga tgcgcttctg ccaaagcttc atgactgaat tgcaaaaaca
      841 catcggacca tcacttgacg tacctgctgg tgatatcggt gttggtggac gtgaaattgg
      901 ttacctttac ggtcaataca aacgtcttaa ccaatttgat gctggtgtct tgactggtaa
      961 acctcttgga tttggtggta gcttgattcg tccagaagca actggttacg gtttggttta
     1021 ctatactgaa gaaatgctca aagctaacgg taacagcttt gctggtaaga aagtcgttat
     1081 ttcaggttct ggtaacgttg ctcaatatgc tcttcaaaaa gcaactgaac tcggtgcaac
     1141 tgttatttct gtttctgact caaatggtta tgtcatcgat gaaaatggta tcgacttcga
     1201 tcttttggtt gatgttaaag aaaaacgtcg tgctcgtttg actgagtatg cagctgaaaa
     1261 agcaactgca acctaccacg aaggtactgt atggacttac gctggaaact atgacattgc
     1321 tcttccatgt gccactcaaa acgaaatcaa cggtgaagca gctaaacgtt tggttgctca
     1381 aggcgttatc tgtgtatctg aaggtgccaa catgccgagc gaccttgatg ccatcaaagt
     1441 ttacaaagaa aatggtatct tctacggacc tgcaaaagct gccaacgctg gtggtgtagc
     1501 cgtttcagct cttgaaatga gccaaaacag tcttcgcctc tcatggactc gtgaagaagt
     1561 tgatggccgt ctcaaagaca tcatgacaaa catcttcaac acagctaaaa cgacttcaga
     1621 aacatacggt cttgataaag actaccttgc aggagctaac attgctgcct ttgaaaatgt
     1681 agcaaatgcc atgattgcac aaggtattgt ttaagattta tttactcaat cctcaatcac
     1741 tacgattggg gatttttagc ttgaattaaa aaattggaaa atctaattaa ataaaatgaa
     1801 atgaaataaa aactgaacaa attgattgcg gaattcaaac caatttctaa catacttcta
     1861 gaaattaatt tgacttttct aatcgatttg ttcatatctt atttcaattt actatactta
     1921 cttaaccctt tttatactca atgaaaatca aagagcaaac taggaagcga gccgcaggct
     1981 gtacttgagt acggcaaggc aaagctgacg tggtttgaag agattttcaa agagtattaa
     2041 acaaaaagaa aaaccgctac tcctaagaat agcgatttaa tcatgttttt aagctactac
     2101 tgtagttgct ctattattta agtgttatga ataacttcaa tatctttaaa gctttttgtt
     2161 agatttataa tttcaactat agccatctct actccttagt ttacagcaaa aaattatgct
     2221 taattcttat tgtttttgta aacaatcagc gaacccaata ctattccatt caacaagcct
     2281 aaagaaatac catattcaac tggaaaatct aaaaaaattg caaacactat tccaatcatc
     2341 acccctagtg aggctattgt taaaattaca tattcatttt ctttcttcat tttctttaca
     2401 cctcatttcc tttttgtata taagctgtag tactctccac caagagttat taagtactta
     2461 tgatttcctg actcaacaat cttaccacct ttcattacaa aaataatatc cgcatcctta
     2521 atcgttgaca atctatgagc tataattat
//
LOCUS       DAVBIC010000094         2473 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.094, whole genome shotgun sequence.
ACCESSION   DAVBIC010000094 DAVBIC010000000
VERSION     DAVBIC010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2473)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2473)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2473
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.094"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            <1..1545
                     /gene="phtA"
                     /locus_tag="VQ664_002082"
     CDS             <1..1545
                     /gene="phtA"
                     /locus_tag="VQ664_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtA"
                     /protein_id="HET2790172.1"
                     /translation="HVESDGLVFDPAQITSRTARGVAVPHGDHYHFIPYSQMSELEER
                     IARIIPLRYRSNHWVPDSRPEQPSPQPTPEPSPGPQPAPNLKIDSNSSLVSQLVRKVG
                     EGYVFEEKGISRYVFAKDLPSETVKNLESKLSKQESVSHTLTAKKENVAPRDQEFYDK
                     AYNLLTEAHKALFENKGRNSDFQALDKLLERLNDESTNKEKLVDDLLAFLAPITHPER
                     LGKPNSQIEYTEDEVRIAQLADKYTTSDGYIFDEHDIISDEGDAYVTPHMGHSHWIGK
                     DSLSDKEKVAAQAYTKEKGILPPSPDADVKANPTGDSAAAIYNRVKGEKRIPLVRLPY
                     MVEHTVEVKNGNLIIPHKDHYHNIKFAWFDDHTYKAPNGYTLEDLFATIKYYVEHPDE
                     RPHSNDGWGNASEHVLGKKDHSEDPNKNFKADEEPVEETPAEPEVPQVETEKVEAQLK
                     EAEVLLAKVTDSSLKANATETLAGLRNNLTLQIMDNNSIMAEAEKLLALLKGSNPSSV
                     SKEKIN"
     gene            1703..>2473
                     /locus_tag="VQ664_002083"
     CDS             1703..>2473
                     /locus_tag="VQ664_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HET2790173.1"
                     /translation="MKINKKYLAGSVATLVLSVCAYELGLHQAQTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISEE
                     LLMKDPNYQLKDEDIISEIKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTSTNDGAVAFARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRGNLSNSRTYRRQNSDNTSRTNW"
BASE COUNT          868 a          454 c          501 g          650 t
ORIGIN      
        1 catgtagaat ctgatggcct tgttttcgac ccagcgcaaa tcacaagtcg aacagctaga
       61 ggtgttgcag tgccacacgg agatcattac cacttcatcc cttactctca aatgtctgaa
      121 ttggaagaac gaatcgctcg tattattccc cttcgttatc gttcaaacca ttgggtacca
      181 gattcaaggc cagaacaacc aagtccacaa ccgactccgg aacctagtcc aggcccgcaa
      241 cctgcaccaa atcttaaaat agactcaaat tcttctttgg ttagtcagct ggtacgaaaa
      301 gttggggaag gatatgtatt cgaagaaaag ggcatctctc gttatgtctt tgcgaaagat
      361 ttaccatctg aaactgttaa aaatcttgaa agtaagttat caaaacaaga gagtgtttca
      421 cacactttaa ctgctaaaaa agaaaatgtt gctcctcgtg accaagaatt ttatgataaa
      481 gcatataatc tgttaactga ggctcataaa gccttgtttg aaaataaggg tcgtaattct
      541 gatttccaag ccttagacaa attattagaa cgcttgaatg atgaatcgac taataaagaa
      601 aaattggtag atgatttatt ggcattccta gcaccaatta cccatccaga gcgacttggc
      661 aagccaaatt ctcaaattga gtatactgaa gacgaagttc gtattgctca attagctgat
      721 aagtatacaa cgtcagatgg ttacattttt gatgaacatg atataatcag tgatgaagga
      781 gatgcatatg taacgcctca tatgggccat agtcactgga ttggaaaaga tagcctttct
      841 gataaggaaa aagttgcagc tcaagcctat actaaagaaa aaggtatcct acctccatct
      901 ccagacgcag atgttaaagc aaatccaact ggagatagtg cagcagctat ttacaatcgt
      961 gtgaaagggg aaaaacgaat tccactcgtt cgacttccat atatggttga gcatacagtt
     1021 gaggttaaaa acggtaattt gattattcct cataaggatc attaccataa tattaaattt
     1081 gcttggtttg atgatcacac atacaaagct ccaaatggct ataccttgga agatttgttt
     1141 gcgacgatta agtactacgt agaacaccct gacgaacgtc cacattctaa tgatggatgg
     1201 ggcaatgcca gtgagcatgt gttaggcaag aaagaccaca gtgaagatcc aaataagaac
     1261 ttcaaagcgg atgaagagcc agtagaggaa acacctgctg agccagaagt ccctcaagta
     1321 gagactgaaa aagtagaagc ccaactcaaa gaagcagaag ttttgcttgc gaaagtaacg
     1381 gattctagtc tgaaagccaa tgcaacagaa actctagctg gtttacgaaa taatttgact
     1441 cttcaaatta tggataacaa tagtatcatg gcagaagcag aaaaattact tgcgttgtta
     1501 aaaggaagta atccttcatc tgtaagtaag gaaaaaataa actaatgaaa aatgaaagtc
     1561 tcgataaaga ggctttcatt tttattatgt atatatgtaa aattcttgac aagcaatatt
     1621 aaaaagagta aactattaac tagttaatta accggtttat tactttatag tgaatcaaat
     1681 atacttaaga aaagaggaaa gaatgaaaat caataaaaaa tatctagctg ggtcagtagc
     1741 tacacttgtt ttaagtgtct gtgcttatga actaggtttg catcaagctc aaactgtaaa
     1801 agaaaataat cgtgtttcct atatagatgg aaaacaagcg acgcaaaaaa cggagaattt
     1861 gactcctgat gaggttagca agcgtgaagg aatcaatgcc gaacaaatcg tcatcaagat
     1921 aacagaccaa ggctatgtca cttcacatgg ggaccactat cattattaca atggtaaggt
     1981 tccttatgac gctatcatca gtgaagaatt gctgatgaag gatccaaact accagctaaa
     2041 ggacgaggat attatcagtg aaatcaaggg tggttatgtg attaaggtag atggaaaata
     2101 ctatgtttac cttaaggatg cagctcatgc ggataatgtc cgtacaaaag aagaaatcaa
     2161 tcggcaaaaa caagaacata gtcagcatcg tgaaggaggg acttcaacaa acgatggtgc
     2221 ggtagccttt gcacgttcac aaggacgcta tactacagat gatggttata tctttaatgc
     2281 ttctgatatc attgaggaca cgggtgatgc ttatatcgtt cctcacggcg accattacca
     2341 ttacattcct aagaatgagt tatcagctag cgagttagct gctgcagaag ccttcctatc
     2401 tggtcgggga aatctgtcaa attcaagaac ctatcgccga caaaatagcg ataacacttc
     2461 aagaacaaac tgg
//
LOCUS       DAVBIC010000095         2309 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.095, whole genome shotgun sequence.
ACCESSION   DAVBIC010000095 DAVBIC010000000
VERSION     DAVBIC010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2309)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2309)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2309
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.095"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            86..1777
                     /locus_tag="VQ664_002084"
     CDS             86..1777
                     /locus_tag="VQ664_002084"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HET2790174.1"
                     /translation="MNTKELIASELASIIDSLDQEAILKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            complement(2113..>2309)
                     /locus_tag="VQ664_002085"
     CDS             complement(2113..>2309)
                     /locus_tag="VQ664_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2790175.1"
                     /translation="RLKPLTVEDKAYNHALSKERSKVENIFAKVKTFKMISTTYRNHR
                     KHFGLRMNLIAGIINHELGF"
BASE COUNT          726 a          489 c          454 g          640 t
ORIGIN      
        1 caaaaaaaca ggagatttca aaaatttttt cttctttctt taaaattgtg ataaaatagt
       61 agaaaagtcc aaaaaggagc tcttaatgaa tacaaaagaa ttgattgcta gcgaattggc
      121 tagcatcatt gatagcctgg accaagaggc tattttaaag ttactggaaa cccctaaaaa
      181 ctcagaaatg ggtgacatcg ctttccctgc tttttctctt gccaaagtcg aacgtaaagc
      241 accacaaatg attgcggctg aactggctga aaaaatgaac agccaagcct ttgaaaaagt
      301 tgtcgcaaca ggaccttacg ttaacttttt ccttgataaa tctgccattt ctgctcaagt
      361 attgcaagct gttaccactg aaaaagaaca ctatgctgac caaaatattg gtaaacaaga
      421 aaatgttgtt atcgacatgt ctagtccgaa tatcgctaaa ccattttcta ttggccacct
      481 gcgttcaact gttatcggag atagcttgtc acatattttc caaaaaatcg gttatcaaac
      541 ggtcaaggtc aaccatttgg gagactgggg taaacaattt gggatgttga ttgttgccta
      601 caaaaaatgg ggcgacgaag aagctgtaaa agctcatcca atcgatgaac tccttaaact
      661 ctatgtccgc atcaacgctg aagctgaaaa tgaccctagc ttggatgaag aagcgcgcga
      721 atggttccgt aaacttgaaa atggagatga ggaagctctc gctctttggc aatggttccg
      781 cgatgaaagt ttagtggaat ttaaccgcct ttacaatgaa ttgaaggttg aatttgacag
      841 ctataacgga gaagccttct acaatgataa gatggatgca gttgtagaca ttctttctga
      901 aaaaggacta cttcttgaat cagaaggtgc ccaagttgtg aatcttgaga aatacggaat
      961 tgaacatcca gccctcatca agaagtctga tggtgcaact ctctatatca cacgtgactt
     1021 ggctgcagcc ctctaccgta aaaacgaata ccaatttgct aaatctatct atgtcgttgg
     1081 tcaagaacaa tctgcccact ttaaacagct caaagctgtc ttgcaagaga tgggctacga
     1141 ctggagtgac gacattactc acgttccttt tggtttggtt acaaaagaag ggaagaaact
     1201 ctctactcgt aaagggaatg tcatcttgct agagcctact gttgcagagg ctgttagccg
     1261 tgccaaggtc caaatcgagg ctaaaaatcc tgaactagaa aacaaagacc aagtagcaca
     1321 tgctgttggg gttggagcca ttaaattcta tgacctcaaa accgaccgta caaatggata
     1381 cgacttcgac ctagaggcta tggtatcctt cgagggtgaa actggacctt acgttcaata
     1441 tgcctacgct cgtatccaat ctatcttacg caaagccgat ttcaaaccag aaacagctgg
     1501 caactatagc ttgaatgata ctgaaagctg ggaaatcatt aaactcattc aagacttccc
     1561 acgtattatc aaccgtgcgg cagataactt tgaaccttct atcattgcta aatttgcaat
     1621 tagcctggct caatccttta acaaatacta tgcacataca cgtatcttgg atgaaagccc
     1681 agaacgcgac agccgtctag ccctcagcta cgcaaccgca gtcgttctca aagaagccct
     1741 tcgcttgctt ggagtagaag cgccagagaa gatgtaaatc gccaaagtta cttgattgca
     1801 aagcaatcta agtaactaac gccaaatcct attcggactt tggctaggcg cttcactagt
     1861 tttaggacat acttcactag ttttaggaca taaatatgat cgatttatgt cctaaaacgt
     1921 cgtaatctta aagttattgg aactaaagtt cctaattgtt agacgctagc cgcttatatg
     1981 cgaactagct aactgcttca ctagtcatga cccctaaata taatcgattt agagtccatg
     2041 acgtcgtaac cagagacact tgcctaaacg cttcactaat tcacctaacc aaataataga
     2101 cttcctgcaa aactagaatc ctagttcatg attgataatg ccagcaatca aattcattcg
     2161 taatccgaag tgtttacgat gatttcgata ggttgttgaa atcattttaa acgtttttac
     2221 tttggcaaag atgttctcaa ccttgcttct ctccttggat agcgcatggt tataggcttt
     2281 atcttcaact gttagtggct tgagtctgc
//
LOCUS       DAVBIC010000096         2204 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.096, whole genome shotgun sequence.
ACCESSION   DAVBIC010000096 DAVBIC010000000
VERSION     DAVBIC010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2204)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2204)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2204
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.096"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            complement(<1..303)
                     /locus_tag="VQ664_002086"
     CDS             complement(<1..303)
                     /locus_tag="VQ664_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HET2790176.1"
                     /translation="MKKTLTPTKESIDSLRNYEASKQLTDARFKRLVGVQRTTFEEML
                     AVLKTAYQLKHTKGGRKPKLSLEDLLMATLQYVREYRTYEEIAADFGIHESNLIRRS"
     gene            complement(248..430)
                     /locus_tag="VQ664_002087"
     CDS             complement(248..430)
                     /locus_tag="VQ664_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HET2790177.1"
                     /translation="MDLKFEGVDLEYKKAKNNLPESFWETYSAFANTNGGKIILGIDE
                     KNIDTYQRVNRLPAKL"
     gene            787..>2204
                     /gene="pcpA"
                     /locus_tag="VQ664_002088"
     CDS             787..>2204
                     /gene="pcpA"
                     /locus_tag="VQ664_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein PcpA"
                     /protein_id="HET2790178.1"
                     /translation="MKKTTILSLTTAAVILAAYVPNEPILADTPSSEVIKETKVGSII
                     QQNNIKYKVLTVEGNIGTVQVGNGVTPVEFEAGQDGKPFTIPTKITVGDKVFTVTEVA
                     SQAFSYYPDETGRIVYYPSSITIPSSIKKIQKKGFHGSKAKTIIFDKGSQLEKIEDGA
                     FDFSELEEIELPASLEYIGTSAFSFSQKLKKLTFSSSSKLELISHEAFANLSNLEKLT
                     LPKSVKTLGSNLFRLTTSLKHVDVEEGNESFASVDGVLFSKDKTQLIYYPSQKNDESY
                     KTPKETKELASYSFNKNSYLKKLELNEGLEKIGTFAFADAIKLEEISLPNSLETIERL
                     AFYGNLELKELILPDNVKNFGKHVMNGLPKLKSLTIGNNINSLPSFFLSGVLDSLKEI
                     HIKNKSTEFSVKKDTFAIPETVKFYVTSEHIKDVLKSNLSTSNDIIVEKVDNIKQETD
                     VAKPKKNSNQGVVGWVKDKGLW"
BASE COUNT          779 a          319 c          362 g          744 t
ORIGIN      
        1 gctccgacgg attaagttgc tttcgtgaat accaaaatca gccgcaattt cttcataagt
       61 gcggtattct cgcacatatt gaagagtggc cataagaagg tcttctaggc ttaatttagg
      121 ttttcgtcca ccttttgtgt gtttaagttg ataagctgtt tttaacacag ctaacatctc
      181 ttcaaaagtg gtgcgctgaa caccaacaag acgcttaaat cgtgcatcgg ttagttgttt
      241 acttgcttca taatttcgca gggagtctat tgactctttg gtaggtgtca atgttttttt
      301 catctatccc gagaattatt ttcccgccat ttgtatttgc aaatgctgag taggtttccc
      361 agaaagactc tggaagattg tttttagctt ttttgtattc taaatcaacc ccttcaaatt
      421 ttaagtccat atttttcctt tacatctgtt ttttgtggtt ctggtatttg ttcaagttga
      481 gtgataatat agcgaattga atttcgagag tttttactca gttaatttct tttttaaccc
      541 actttaattt cttttttaac ccactttaat ttctttttta acacgggtta aaaaagaaat
      601 taaagtgggt taatttttct tgacttaaaa tttaaaaatg atatactgtg tttatggaga
      661 gatgacaatt tataaaatgt actactctat tctactagat aatgattgaa taaaactttt
      721 tataacaacg gctagcaaag ttataatttt atatctatta gaaaataaat atgtaaggaa
      781 atttaaatga aaaaaactac aatattatca ttaactacag ctgcggttat tttagcagca
      841 tatgtcccta atgaaccaat cctagcagat actcctagtt cggaagtaat caaagagact
      901 aaagttggaa gtattattca acaaaataat atcaaatata aggttctaac tgtagaaggt
      961 aacataggaa ctgttcaagt gggtaatgga gttactcctg tagagtttga agctggtcaa
     1021 gatggaaaac cattcacgat tcctacaaaa atcacagtag gtgataaagt atttaccgtt
     1081 actgaagtag ctagtcaagc ttttagttat tatccagatg aaacaggtag aattgtctac
     1141 tatcctagct ctattactat cccatcaagc ataaaaaaaa tacaaaaaaa aggcttccat
     1201 ggaagtaaag ctaaaactat tatttttgac aaaggcagtc agctggagaa aattgaagat
     1261 ggagcttttg atttttctga attagaagag attgaattgc ctgcatctct agaatatatt
     1321 ggaacaagtg cattttcttt tagtcaaaaa ttgaaaaagc taaccttttc ctcaagttca
     1381 aaattagaat taatatcaca tgaggctttt gctaatttat caaatttaga gaaactaaca
     1441 ttaccaaaat cggttaaaac attaggaagt aatctattta gactcactac tagcttaaaa
     1501 catgttgatg ttgaagaagg aaatgaatcg tttgcctcag ttgatggtgt tttgttttca
     1561 aaagataaaa cccaattaat ttattatcca agtcaaaaaa atgacgaaag ttataaaacg
     1621 cctaaggaga caaaagaact tgcatcatat tcgtttaata aaaattctta cttgaaaaaa
     1681 ctcgaattga atgaaggttt agaaaaaatc ggtacttttg catttgcaga tgcgattaaa
     1741 cttgaagaaa ttagcttacc aaatagttta gaaactattg aacgtttagc cttttacggt
     1801 aatttagaat taaaagaact tatattacca gataatgtta aaaattttgg taaacacgtt
     1861 atgaacggtt taccaaaatt aaaaagttta acaattggta ataatatcaa ctcattgccg
     1921 tccttcttcc taagtggcgt cttagattca ttaaaggaaa ttcatattaa gaataaaagt
     1981 acagagtttt ctgtgaaaaa agatacattt gcaattcctg aaactgttaa gttctatgta
     2041 acatcagaac atataaaaga tgttcttaaa tcaaatttat ctactagtaa tgatatcatt
     2101 gttgaaaaag tagataatat aaaacaagaa actgatgtag ctaaacctaa aaagaattct
     2161 aatcagggag tagttggttg ggttaaagac aaaggtttat ggta
//
LOCUS       DAVBIC010000097         2120 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.097, whole genome shotgun sequence.
ACCESSION   DAVBIC010000097 DAVBIC010000000
VERSION     DAVBIC010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2120)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2120)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2120
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.097"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            114..1031
                     /locus_tag="VQ664_002089"
                     /pseudo
     CDS             114..1031
                     /locus_tag="VQ664_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001822901.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
     gene            complement(1071..2015)
                     /gene="manA"
                     /locus_tag="VQ664_002090"
     CDS             complement(1071..2015)
                     /gene="manA"
                     /locus_tag="VQ664_002090"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HET2790179.1"
                     /translation="MSEPLFLQSVMQEKIWGGTKLRDEFGYDIPSEKVGEYWAISAHL
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDALLTKVPVKAG
                     DFFYVPSGTMHAIGAGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTIKADDLRSTILVSNDFFAVYKWEITGKVNFEKTADYSLLSVLAGQGQL
                     TVDGKNYPIQKGRHFILPSDVESWTLEGQDLELIVSHP"
BASE COUNT          540 a          490 c          406 g          684 t
ORIGIN      
        1 aaaagtcgtg cgctgaacac caacaagacg cttaaatcgt gcatcagtta gttgtttact
       61 tgcttcatca ttcatagaac tactatgcca tattttgttt cgcaggaagt ctgatcattt
      121 caaatccagc cattgctcta ggagctcaag cgacctttat cctattgaat atcttcattg
      181 tatcacgtgg ggttcaaaaa gggattgaaa gagcttcgaa agtcatgatg cccctgctct
      241 ttatcatctt tgtcgtcatc atcgaacgct ctctcagttt gccaaatgcc atggaagggg
      301 ttctttactt cctcaaacca gatttttcaa aactgactag cgctggtctc ctctatgctc
      361 tgagacaatc tttctttgcc ctctcactag gggttacagc catgttgacc tatgcttctt
      421 acttggacaa gaaaaccaat ctggtccagt caagaatctc catcgtagcc atgaatatct
      481 cggtatccat catggcaggt ctagccattt tccaagctcg gtcccccttc agactgaata
      541 ttgaaggggg accgagcttg gtctttatcg tcttgcctca actctttgac aagatgcctt
      601 ttggaaccat tttctatgtc ctcttcctct ttgcgactgt cacttcttct gtcgttatgc
      661 tggaaatcaa tgtagacaat atcaccaatc aggacaacag caagcgtgct aaatggagtg
      721 ttattttagg aattttgacc tttgtctttg gcattccttc agccctatct tacggtgtca
      781 tggcggatgt tcacattttt ggtaaagcct tctttgacgc tatggacttc ttggtttcca
      841 atctcctcat gccatttgga gctctcttcc tttcactttt tacaggctat atctttaaaa
      901 aggctcttgc aatggaggaa ctccatctcg atgaaagagc atggaaacaa ggactgttcc
      961 aagtctggct cttccttctt cgtttcgtca ttccaatcat catcgtggtc ttcatcgccc
     1021 aatttatgta atcaaaagga cttgagtaat gaactcaggt cctttctttt ttatggatga
     1081 ctaacaatta attctaaatc ttgcccttct agagtccaag attcaacatc acttggtagg
     1141 ataaagtgtc tccctttttg gattggatag tttttcccgt caacagttag ttgaccttga
     1201 ccagccaaga cactcaacaa gctgtagtca gctgtctttt caaagttaac ttttccagta
     1261 atttcccatt tgtaaactgc gaagaaatca ttggatacaa ggatagtgga acgtagatca
     1321 tctgctttga ttgtcactgg acggctattt gcgggttcac caatgttcaa gacatcgata
     1381 gatttttcaa ggtgaagttc acgtaaattg cccttgtcat ccttacggtc aaagtcatag
     1441 acacggtaag tggtatcgct agactgctgg gtttcaagaa tcaagatacc cgccccgata
     1501 gcgtgcatgg taccgcttgg tacatagaag aaatctcctg ctttaactgg cacttttgtc
     1561 aacagcgcat cccagttctt atcctcgatt tgctggcgga gttcttcttt tgacttggca
     1621 ttgtgaccgt agataatctc tgaaccttca tctgctgcaa tgatgtacca acattctgtt
     1681 tttccaagtt cgccttcatg ctcgagtcca taagcatcgt ctgggtgaac ttggacactg
     1741 agccagtcgt tggcatcgag gatcttggtc aaaagtggaa atacaggttc tggacgattg
     1801 ccaaataatt cacggtgttc cgcatacaaa gtagcaagat ctgttccctc gtaacgacca
     1861 ttggcaactt tagaaacacc atttagatga gctgagatag cccagtactc tccgactttt
     1921 tcacttggga tgtcgtagcc aaactcatca cgtagcttgg taccacccca gattttttct
     1981 tgcataactg attgtaaaaa taatggttct gacatcttaa tctcctgtct gatttttctc
     2041 ccctcattat agcaaaaaaa gagttccatt tgaactcttt tttacatctt ataaagcagg
     2101 gagaagattt tataaaaata
//
LOCUS       DAVBIC010000098         1651 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.098, whole genome shotgun sequence.
ACCESSION   DAVBIC010000098 DAVBIC010000000
VERSION     DAVBIC010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1651)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1651)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1651
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.098"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            108..407
                     /locus_tag="VQ664_002091"
     CDS             108..407
                     /locus_tag="VQ664_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic biosynthesis protein"
                     /protein_id="HET2790180.1"
                     /translation="MDSYAINFWESKGVGIDKKILEFIQKNITVIKNKNFLNKDFDIY
                     VKKIHNLFFVISTLVSKEQYMGIVSSQIHMFANRMGISPTIEVTMLDFFLREDSD"
     gene            409..1179
                     /locus_tag="VQ664_002092"
     CDS             409..1179
                     /locus_tag="VQ664_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SagB/ThcOx family dehydrogenase"
                     /protein_id="HET2790181.1"
                     /translation="MEKYFFDISIFEKIKKVLSYQSKYWEISKPRDKYSFKSQNRISG
                     SNSIKFKDFELDYELESLGKILLKRRSFLLNEFDKNASFDKLIYLLKTVFSPTNCKFV
                     FGEEVPLFSYPTSGALNSITPFVYIDNMDEVKNGIYEVKYDGLEFKKSMNIIDLETFT
                     PITSKNSDVQNNSFKKVNMIIMLCSNYENIFNKYGLLAYRLLHLEAGHIAQNIQLVST
                     ALGIKSLPMGGWFDDKIETFINEISDKKNIYLYAIAVG"
     gene            1199..1363
                     /locus_tag="VQ664_002093"
     CDS             1199..1363
                     /locus_tag="VQ664_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2790182.1"
                     /translation="MNAEDKFRELENENKLLKLHNKELENEIQNGWKFWIWVTVPILG
                     LIYAIIQKIF"
BASE COUNT          608 a          181 c          269 g          593 t
ORIGIN      
        1 ataactatta ttacgaaaaa aaattcttgt gtaaaattct attgactttc tatattattt
       61 ttgtatttca taacgaatgt aatttaacaa gtgaagaaat tttaaagatg gattcctatg
      121 ctattaattt ctgggagagt aaaggggtcg gtattgacaa aaaaatcttg gaatttattc
      181 aaaaaaatat tacagttatt aaaaataaaa attttttgaa taaagatttt gatatttatg
      241 ttaaaaagat tcataattta ttctttgtca tttctacttt agtttcaaaa gagcaataca
      301 tggggatagt ttcttcccaa atacatatgt tcgcaaatag gatgggaatt tctcccacca
      361 ttgaagttac catgctagat ttttttctga gggaggattc tgattaatat ggaaaaatat
      421 ttttttgata tttctatttt tgaaaaaata aaaaaagtat tatcatacca atctaaatat
      481 tgggaaatat cgaagcctag ggataagtac agtttcaaaa gtcaaaatag aatatctggc
      541 tctaatagca ttaaatttaa agattttgag ttagattatg aactggagtc acttggtaaa
      601 atacttttaa aaaggagatc gtttttacta aatgaatttg ataagaatgc gagttttgac
      661 aaactgattt acttgttgaa aactgtattc tctcctacaa attgcaagtt tgtatttgga
      721 gaagaggttc ctttatttag ctatcctaca tcaggtgcgt taaattcaat tactcctttt
      781 gtttatattg ataatatgga tgaagtaaag aatggtatat atgaagtaaa gtatgacgga
      841 cttgaattta aaaaaagtat gaatattata gacttagaaa catttacccc aataacaagt
      901 aaaaacagtg acgtacaaaa taattcattt aaaaaggtaa atatgataat tatgttatgt
      961 tcgaattatg aaaatatttt caataaatat ggattattag cttatcgact tttgcattta
     1021 gaggctggtc atattgcaca aaatatccag cttgtttcta ctgcgctagg aataaaaagt
     1081 ttaccgatgg gaggttggtt tgatgataaa atagaaactt ttattaatga aattagtgat
     1141 aaaaaaaata tttatctcta tgcaattgca gttggataaa tttaaggagg aagtgtagat
     1201 gaacgcagag gataaatttc gcgaactaga aaatgaaaat aaacttctaa aacttcataa
     1261 caaggagctt gagaatgaaa ttcaaaatgg atggaaattt tggatatggg taactgtccc
     1321 tattttaggt ttgatatatg ctattattca aaaaattttt taattatgct agtttgtcag
     1381 gttgagtagt ttttgttcaa aatttaataa acttttttca atgaagatta tctaaagatt
     1441 gcttctcaga tgagaatggc ttctctatct tatataaatt atcttcatag agtgtcctgt
     1501 tattcatgtt atcacagaat agatagtttt tttggctcta taatatttgt agtgggtaaa
     1561 tcccctatag atattatgga gcctattttt gtgtagaaaa aaagtcccat atcatctata
     1621 atgaaaagca accaaactat cattagaaag a
//
LOCUS       DAVBIC010000099         1606 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.099, whole genome shotgun sequence.
ACCESSION   DAVBIC010000099 DAVBIC010000000
VERSION     DAVBIC010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1606)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1606)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1606
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.099"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            complement(<1..689)
                     /locus_tag="VQ664_002094"
     CDS             complement(<1..689)
                     /locus_tag="VQ664_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HET2790183.1"
                     /translation="MCYTCCSTTNTRKAQRCKTIILQKANKGKSNREIASLLGKAPQT
                     IHTEIKRRTVRQCLGKGRFKEVYSADYAQQSYENNRKRSVKKSSLTKELKEKILHYHN
                     QKFSPEMMVMAKGVNVGISTIYYWIHHGKLGLSKQDLPYPRKGKALKKQASTNFKPAG
                     QSIEQRLEAINFRLENGHYEIDTVLLTRAKNYCLLVLTDRKSRHQIIRLIPNKSAEVV
                     NQALKLILKQH"
     gene            complement(1063..1461)
                     /locus_tag="VQ664_002095"
     CDS             complement(1063..1461)
                     /locus_tag="VQ664_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2790184.1"
                     /translation="MENKESHKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAP
                     DFYQKHGYKEVFSLQDYLYIRQRYYYQKNL"
BASE COUNT          461 a          315 c          266 g          564 t
ORIGIN      
        1 ttgtgttgtt ttaagatgag ttttagagcc tgattgacca cctcagcact tttatttgga
       61 atcaatcgga tgatctgatg tctacttttt cgatccgtca agacaagcaa gcagtagttt
      121 ttcgctctcg taagtagaac tgtatcaatc tcataatgcc cattctccaa gcgaaaattg
      181 atagcttcaa gccgctgttc gatggattga ccagcaggtt taaagttggt gctagcctgt
      241 ttcttaagcg cttttccttt tctagggtaa ggcaaatcct gcttgcttaa ccccaatttt
      301 ccatgatgaa tccaatagta aatggttgaa attcccacgt taaccccttt agccataacc
      361 atcatttcag gcgaaaattt ttggttatga tagtggagaa tcttttcctt tagttccttg
      421 gtcaagcttg atttcttgac cgagcgcttg cgattgtttt cataagactg ttgagcatag
      481 tcggcagaat aaacctcttt gaagcgccct tttccaagac attgtcggac tgtcctacgc
      541 ttgatttcag tgtggatagt ttgaggagct tttccaagta gagaggcaat ttctctattt
      601 gatttccctt tgttcgcctt ttgtagtata atggttttgc atctctgtgc ctttcttgtg
      661 tttgtggttg aacaacaagt ataacacaaa ggtgttttct tatgcctaca agagctttca
      721 ttatttccat tttcttttgg atttcactct attctgaaaa acttgtgtat atttactgaa
      781 gctagcaagt cttacctgta aatttaatga aagcaacaca aaatccgaga ggggaatctc
      841 ggattaatgt caatttaaaa agatagagag tttttagttt aaataaattg ttttaaaata
      901 tcaacaacat cacttctttt cttaacctga taagccttga ttcctaattt tggggctacg
      961 attatattgt cctcaatatc gtctagaaag acacaatttc taggttataa ctggtattta
     1021 tcgatagtta ctcatatata tcagtccacc tccatactca ccttacagat tcttttgata
     1081 ataatatctt tgcctaatgt agagatagtc ttgcaaagaa aaaacttcct tgtagccatg
     1141 tttctgataa aagtccggtg cctggaactg gtaagtattg acaaaggcaa aacaacaatt
     1201 tcgattctta gcttcacttt ctgcctgttg caatagtttt gaaccgattc cttgccctcg
     1261 cagttcctct tttacaaaca aatactcgat ttctagccaa tttccaaaag tctctgctat
     1321 caaacccgca aggagattgc ccttttcatc ttcgacataa agattaagtg gctcactttc
     1381 agcctcttct ctttttgaac ggttataaac acgaatcaga ttccctattt cttgcgattt
     1441 atgtgattcc ttattttcca atctaaagta taatgaaatg aaataaaaca tgcgcaaatc
     1501 gattaaggaa tttaatctaa tttctaacaa tgtcttagaa atcaaagtgt actattttaa
     1561 cttcaatgca ctatacatct aatactcaat aaaaatcaaa gagcaa
//
LOCUS       DAVBIC010000100         1586 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.100, whole genome shotgun sequence.
ACCESSION   DAVBIC010000100 DAVBIC010000000
VERSION     DAVBIC010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1586)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1586)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1586
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.100"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            84..491
                     /locus_tag="VQ664_002096"
     CDS             84..491
                     /locus_tag="VQ664_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET2790185.1"
                     /translation="MARYGVYAVIPNPEQKQIVLVQEPNGAWFLPCGEIEAGENHQEA
                     LKRELIEELGFTAEIGTYYGQADEYFYSRHRDTYYYNPAYLYEATSFKEVQKPLENFN
                     HIAWFPIDEAIQNLKRGSHKWAIESWKKQHKIG"
     gene            656..955
                     /locus_tag="VQ664_002097"
     CDS             656..955
                     /locus_tag="VQ664_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HET2790186.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKTSVNEANIKTLYSEKLIGISIPIK"
     gene            1216..1539
                     /gene="tnpB"
                     /locus_tag="VQ664_002098"
     CDS             1216..1539
                     /gene="tnpB"
                     /locus_tag="VQ664_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HET2790187.1"
                     /translation="MMIVLSDLGQVHLVCGKTDMRQGIDSLAYVVKTHFELDPFSGQV
                     FLFCGGRKDRFKALYWDGQGFWLLYKRFENGRLTWPSTEKDVKALTSEQVDWLMKGFS
                     ITPQI"
BASE COUNT          544 a          314 c          282 g          446 t
ORIGIN      
        1 actataataa taacgatact agataatgag gaaaatgcaa tggcaaaccc aactttcgga
       61 gaaaaaaagc gaatacagac tatattgctc gctatggcgt atatgcagtt atccctaatc
      121 ctgaacaaaa acaaattgtt cttgttcaag aaccaaatgg tgcttggttc ctaccatgtg
      181 gagaaattga agcaggtgaa aatcatcagg aagccctaaa gcgtgagttg attgaagagc
      241 ttggtttcac agcagaaatt ggtacctatt acggacaagc tgacgaatat ttctattctc
      301 gtcatcgtga tacctactac tacaatcctg cctacctcta tgaagcaact tctttcaaag
      361 aagtacaaaa gccactagaa aactttaatc atattgcctg gttccctatt gacgaggcta
      421 tccaaaacct taaacgtggt agccataaat gggccattga atcttggaaa aaacagcata
      481 agattggcta atactcttcg aaaataaaat tcaaaccacg tcagcgtcgc cttaccgtac
      541 tcaagtatag cctgcggcta gcttcctagt ttgctctttg attttcattg agtataaatc
      601 aagcgacttt attcaaaaag tgctataata gaattagaaa atcggaggaa atattatgaa
      661 gcttatcaat acgacaaact cacactcgca acttgtaaaa agtcaactag aaagtaccga
      721 tgcaaccctt gttgaggttt attctgcagg gaatacagat gttattttta cccaagctcc
      781 gcttcactat gaaatcctca tctcaaacaa acaccgtgct attcgtgagc ctgaaatcga
      841 aaccattcaa gaatttttct tgaaacgtaa aattgataag acctctgtta atgaagccaa
      901 tatcaagaca ctctactcag agaaattaat tggaatttca atcccaatca agtaagaaaa
      961 ttgagtaaaa actcgatttg agagaaagtc caataagtct ttccataaca aaacgcatag
     1021 taacaagagt ttctacaccc actattatac gtttttatca ttttgaaatc tgctgctaat
     1081 caatgaagaa gcaaagatca aactaggcag ctagttacaa gttacgtaag cgcgtcataa
     1141 caaggtatct atcctaattc cccaacttcc agtatactag ataaaaaata attatcagag
     1201 gaaaggtatt gtactatgat gattgtacta agtgatttag gtcaagttca ccttgtttgt
     1261 ggcaagacag atatgaggca gggaatagac tcattagcct atgtagttaa aacccacttt
     1321 gaattggatc ctttctccgg tcaagtcttt ctcttttgtg gtggacgtaa agaccgcttt
     1381 aaagcccttt actgggatgg tcaaggattt tggctactat ataaacgctt tgagaacggc
     1441 agactgactt ggcccagtac agaaaaggat gtcaaagctc tcacatctga acaagtagac
     1501 tggcttatga agggcttttc tatcactccc caaatatagt ggatttaaac tagaatagta
     1561 cacctctact tctaaaacat tgttag
//
LOCUS       DAVBIC010000101         1487 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.101, whole genome shotgun sequence.
ACCESSION   DAVBIC010000101 DAVBIC010000000
VERSION     DAVBIC010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1487)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1487)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1487
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.101"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            complement(1..229)
                     /locus_tag="VQ664_002099"
                     /pseudo
     CDS             complement(1..229)
                     /locus_tag="VQ664_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            498..1303
                     /locus_tag="VQ664_002100"
                     /pseudo
     CDS             498..1303
                     /locus_tag="VQ664_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
BASE COUNT          513 a          259 c          280 g          435 t
ORIGIN      
        1 cagtattaca tccaccagct attaagaaaa atgattcgcc tgtatgggca tcaacagctc
       61 cataacaata gtgaaattct cgtatatagt gactatggac atgtggacct actcctattg
      121 gagaccaaca agatcccagt ttactgattc taccgaagcc agcctcatct tggtacatca
      181 agcgaacctt atgaaaacgt ctactggttt taaagcgctt tcttttcttc agttgatttc
      241 atatcactat tgtataatgc tttttgattt tagtctagta taaatagcga gaaatatcta
      301 tcctatcttc tagaatgtct tccaaacgag gaaactctcg taaacaaaga ggttttagag
      361 gcctatttac cgtggactaa agttgcacaa gaaaagtgca aataagaaat ctccagatta
      421 ggaactatcc gtgagttctc tagtctggag atttttcaat agacttcctg cgaaacaaaa
      481 tatggtataa tagttctatg aattatgaag caagtaaaca actaaccgat gcacgattta
      541 agcgtcttgt tggtgttcaa cgcacgactt ttgaagagat gttagctgta ttaaaaacag
      601 cttatcaact taaacacgca aaaggtggac gaaaacctaa attaagccta gaagaccttc
      661 ttatggccac tcttcaatat gtgcgagaat atcgaactta tgaagaaatt gcggctgatc
      721 ttggtattca cgaaagcaac ttactccgtc ggagccaatg ggttgaagta actcttgttc
      781 aaaggtggtg ttgcgatttc aagaactcct ctcagttctg aggacacggt aatgattgat
      841 gcgacggaag taaaaatcaa tcgacctaaa aaaagaatta gcgaattatt ctggtaaaaa
      901 gaaatttcac gctatgaaga ctcaagcgat tgtcacaagt caagggagaa ttatttcttt
      961 ggatatcgct gtgaactatt gtcatgatat gaagttgttc aaaatgagtc gcagaaatat
     1021 cggacaagct ggtaaaatct tggctgacag tggttatcaa gggctcatga agatatatct
     1081 tcaagcacaa actccacgta aatccagcaa actcaagccg ctaacagctg aagataaagc
     1141 ctgtaaccat gtgctatcta aggagagaag caaggttgag aacatctttg ccaaagtaaa
     1201 aacgcttaaa atgttttcaa caacctatcg aaatcatcgt aaacgcttcg gattacggat
     1261 gaatttgatt gttggtatta tcaatcatga actaggattc tagttttgca ggaagtctat
     1321 tatcaaaaat accatcagga ttatataaga ttgatacagg aaaagtttta ttttatggta
     1381 taaatattaa tcaaatagat aaaaaaatat taagtcaaaa tttaggagta gttccacagg
     1441 attcattttt attgaaccga agtattcttg ataatataac tttaaag
//
LOCUS       DAVBIC010000102         1114 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.102, whole genome shotgun sequence.
ACCESSION   DAVBIC010000102 DAVBIC010000000
VERSION     DAVBIC010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1114)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1114)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1114
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.102"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            2..>1114
                     /locus_tag="VQ664_002101"
     CDS             join(2..341,341..>1114)
                     /locus_tag="VQ664_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HET2790188.1"
                     /translation="MVKLIDRYGIEIVKKGKNRHYSSKLKQEMMDKALLEGCSQRSIS
                     LDYALPNQGMLSFWPAQYKKNGYTIVEKTRGRPAKMGRKRKKTWEEMTELERLQEENE
                     RLRTEVAYLKKFKRVRGKGRSPRARKAETVREMVSGGFRLDFLLETARLARSTYYYQL
                     KQLDGVDKDKEIKTEIQGIDNEHKGNYGYRRIHLELRNRGFVVNHKKVQRLMRILGLT
                     ARIRRKRKYSSYQGEIGKKAENLIQRQFEASRPMEKCYTDVTEFAIPNSTQKLYLSPV
                     LDGFNSEIIAYHLSTSPNLEQVKSMLEQAFTEKYYENTILHSDQGWQYQHDSYHRFLE
                     SKGIQASMSRKGNSPDNGMMESFFGILKSEMFYGYEK"
BASE COUNT          392 a          193 c          254 g          275 t
ORIGIN      
        1 catggtgaaa ttaattgacc gttatggcat agaaatcgtt aaaaaaggga agaatcgtca
       61 ctattcttct aaattgaaac aagaaatgat ggataaagcc ttactggaag gttgttcaca
      121 aagaagtatt agtcttgatt atgccctccc aaaccaagga atgctttcat tttggccggc
      181 acaatacaag aaaaacgggt atactattgt tgagaaaaca agagggagac cagctaaaat
      241 gggacgtaaa cggaagaaga cttgggaaga aatgacagaa ctagaacgac tccaggagga
      301 gaatgaacgc ttacggactg aggtggccta cctaaaaaag ttaaaagagt tagaggaaag
      361 ggacgaagcc ctagagcgag aaaggcagag acagttagag aaatggtttc aggaggattt
      421 cgactagatt ttcttcttga aacagcacgt ttagctcgct cgacttacta ttatcagttg
      481 aaacaactgg atggggttga taaagataaa gagattaaaa ccgaaattca gggcattgat
      541 aatgaacata aaggcaacta tggctatcgt cgaatccatt tagaactaag gaatcgtggt
      601 tttgtggtca atcataagaa agttcaacgg ttgatgagaa ttcttggttt aacggctcga
      661 attcgccgta aacggaagta ttcttcctac caaggagaga ttggcaagaa agcagagaat
      721 ctcattcaac gccagttcga agcatcgagg ccaatggaaa agtgctatac agatgtgaca
      781 gagtttgcca ttccaaatag cacacagaaa ctctatttat caccagtttt agatggtttt
      841 aacagtgaaa tcattgctta tcatctttct acttcgccaa acttagaaca agtgaagagt
      901 atgttagaac aggcctttac agagaaatac tatgagaata cgattctcca tagtgaccaa
      961 ggctggcaat accaacacga ttcttatcat cggttcctag agagtaaggg aattcaagca
     1021 tccatgtcac gcaagggcaa cagcccagac aacggcatga tggaatcttt ctttggcatt
     1081 ttaaaatccg aaatgtttta tggctatgag aaga
//
LOCUS       DAVBIC010000103         1054 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.103, whole genome shotgun sequence.
ACCESSION   DAVBIC010000103 DAVBIC010000000
VERSION     DAVBIC010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1054)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1054)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1054
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.103"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            <1..555
                     /locus_tag="VQ664_002102"
     CDS             <1..555
                     /locus_tag="VQ664_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET2790189.1"
                     /translation="KDETTSYPIYEIPEAWRYIKFASLVNFRIGKTPPRSEATFWGTE
                     IPWVSISDMPISGYVTNTRESISKLALKSKKIDISPKGTLLMSFKLSIGKVAILDIPA
                     THNEAIISIFPYANKENIIRDYLMIFLPLISTLGDSKDAIKGKTLNSTSISELLIPIS
                     NHEEMKRIISKVDLLFQKVSQLFE"
     gene            complement(503..1048)
                     /locus_tag="VQ664_002103"
     CDS             complement(503..1048)
                     /locus_tag="VQ664_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001104691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET2790190.1"
                     /translation="MNWVVIKIKDIFSINTGLSYKKGDLSINNKGVRIIRGGNIKPLE
                     FSLLDNDYYIDTQFISSEQVYLKHNQLITPVSTSLEHIGKFARIDKDYDGVVAGGFIF
                     QLTPFESSEIISKFLLFNLSSPLFYKQLKAITKLSGQALYNIPKTTLSELLIPLAPFE
                     EQELITQKVEKLFEKVNQLWK"
BASE COUNT          380 a          165 c          153 g          356 t
ORIGIN      
        1 aaagacgaaa caacctctta tcctatatat gaaatcccag aagcatggag atatattaaa
       61 tttgctagcc tagttaactt cagaatagga aaaactcctc cacgcagtga agctactttt
      121 tggggaactg aaataccttg ggtatctata tcagatatgc ctatatctgg ttatgtaact
      181 aatacgagag aatctatttc taaattagca ttaaaatcaa agaaaataga catttcacct
      241 aaaggaactt tattaatgag ttttaaatta tctattggaa aagttgccat attggatatt
      301 cctgccactc ataatgaagc cattatatcg atattcccct atgctaataa agaaaatatt
      361 atcagagatt acttaatgat atttttgcca cttatctcta ctttaggtga ttcaaaagat
      421 gctataaaag ggaaaacatt aaatagtacc agtatctccg aattattaat ccctatttct
      481 aatcatgaag agatgaaaag aatcatttcc aaagttgatt tactttttca aaaagtttct
      541 caactttttg agtaataagt tcctgttcct caaaaggagc taacggaatt aatagctcgc
      601 ttagtgtagt tttaggaata ttatataaag cttgacctga tagtttagtt attgctttca
      661 attgtttata aaataacgga gaggacaagt taaataatag aaattttgaa ataatctctg
      721 aactttcgaa tggtgttaat tggaaaataa atccaccagc cacaacacca tcatagtctt
      781 tatcgattct tgcaaacttt ccaatatgtt ctaaagaggt tgatacaggt gttattagct
      841 gattatgttt taaataaact tgctcagagg agatgaattg tgtatcaatg tagtaatcat
      901 tatccaacag agaaaattct aaaggcttaa tattaccacc acgtataatt ctaacacctt
      961 tattattaat gcttaaatcg cccttcttgt aagaaagacc tgtatttatt gaaaaaatat
     1021 cttttatttt tataacaacc caattcatag gtat
//
LOCUS       DAVBIC010000104         1035 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.104, whole genome shotgun sequence.
ACCESSION   DAVBIC010000104 DAVBIC010000000
VERSION     DAVBIC010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1035)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1035)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1035
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.104"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            complement(<1..990)
                     /gene="ltrA"
                     /locus_tag="VQ664_002104"
     CDS             complement(<1..990)
                     /gene="ltrA"
                     /locus_tag="VQ664_002104"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HET2790191.1"
                     /translation="MSKLLDKILSRDNMLEAYNQVKSNKGSAGIDGITIEEMDGYLRQ
                     NWRLTKELIKQRKYKPQPVLRVEIPKPNGGIRQLGIPTVMDRMIQQAIVQVISPICEP
                     HFSDTSYGFRPNRSCEKAIMKLLEYLNDGYEWIVDIDLEKFFDTVPQDRLMSLVHNII
                     EDGDTESLIRKYLHSGVIINGQRYKTLVGTPQGGNLSPLLSNIMLNELDKELEKRGLR
                     FVRYADDCVITVGSEAAAKRVMYSVSRFIEKRLGLKVNMTKTKITRPRELKYLGFGFW
                     KSSDGWKSRPHQDSVWRFKLKLKKLTQRKWSIDLTRRIEQLNLSIRGWINYFSL"
BASE COUNT          270 a          226 c          183 g          356 t
ORIGIN      
        1 caatgagaaa tagtttatcc atcctcgaat agacaaattc agttgctcaa tacgtcttgt
       61 taggtctata ctccatttcc tctgtgttag tttcttcaat ttaagcttaa atctccaaac
      121 actatcttga tgtggacgac ttttccaacc atctgatgat ttccagaacc cgaaacctag
      181 atatttcaac tctcttggtc tggtaatctt agtcttggtc atgtttactt tcagacctag
      241 ccgtttctca ataaaacgac tgactgaata catcacacgc ttagcggctg cctcgcttcc
      301 gaccgtaatc acacaatcgt ctgcgtagcg aacaaatcga agccctctct tttctaattc
      361 cttgtccaat tcattaagca tgatattgga taagagagga gataaatttc ctccctgtgg
      421 cgtgccaact agcgttttat aacgttgacc gttaatgata acacctgaat gaagatattt
      481 acgaatcaag gattccgtat ctccgtcttc gataatgtta tgtactaagg acatcaatct
      541 atcttgagga actgtatcga aaaatttctc taggtctatg tccactatcc actcatagcc
      601 gtcatttaag tactctaaga gcttcatgat ggctttttca catgacctat ttggtctgaa
      661 tccatagctc gtatctgaga aatggggttc acaaataggg ctaataactt gaacaatggc
      721 ctgttgaatc attctatcca taactgttgg aattcctagt tggcggatgc ctccgtttgg
      781 tttgggaatc tcaactctaa gaactggttg aggcttatat tttctctgtt ttatcagttc
      841 cttagtcagg cgccagtttt gtctgagata gccatccatc tcttcgatag taattccatc
      901 aatcccagct gagcctttat tagattttac ttgattgtag gcttcaagca tattgtcgcg
      961 tgataatatt ttatctagca attttgacat gtgcctattc ctttcttgtt ttggtgcctg
     1021 agggacatct tatat
//
LOCUS       DAVBIC010000105          979 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.105, whole genome shotgun sequence.
ACCESSION   DAVBIC010000105 DAVBIC010000000
VERSION     DAVBIC010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 979)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 979)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..979
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.105"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            232..708
                     /locus_tag="VQ664_002105"
                     /pseudo
     CDS             232..708
                     /locus_tag="VQ664_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
     gene            746..>979
                     /locus_tag="VQ664_002106"
     CDS             746..>979
                     /locus_tag="VQ664_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HET2790192.1"
                     /translation="MIKILAACGAGVNSSYQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILF"
BASE COUNT          339 a          160 c          182 g          298 t
ORIGIN      
        1 gtgttttgaa caacctgcgg ctagcttcct agtttgctct ttgattttca ttgagtatta
       61 gaacagaaaa aatgcttgga gtatttgttt gtgtgtttac ttttatataa caaactataa
      121 acacaacaaa aatataaaaa aagagacaaa aaagaacaga aagtaattaa caacgatttc
      181 atatagtgtt atacttatag cataaagtta atggaaagaa gggaaaacct tatggtatta
      241 gattatttct ttgacaaaaa ccttgtgttt tgcttagaag cggataatca agaataactc
      301 tttgatcagg tagcaagctt gttggaggaa cgagaaattg taactccaac ttatcgtgaa
      361 gccttgatca cgcgtgaaaa gtcatttcca actggtttag atatggaatt tctaggaaag
      421 gacttgccaa atgtagcgat tcctcataca gatattgttc ataatctagc tgagaaagtg
      481 gtggttgttc gattagaaaa accagtaact tttcacaata tgatagctcc tgataaggaa
      541 gtagaagtat ccctactctt ctttatcatt aacaattcaa gttcaagtca aacaaatatt
      601 ctggctcagt tgatggactt tttcacagga aatggacatc ttgaagatct atcaaaaatt
      661 tccgaaccag aaaaacttta tgcttacatt gctgaagcaa ccgcttaatc ttgtctatta
      721 aaaaataaaa tcggaggaaa tccaaatgat taaaattctt gctgcctgcg gtgcaggtgt
      781 taactcaagt taccaaatta aaagtgctct agaagaagaa ctttcaaacc gtggttatga
      841 tgttcactgt gatgcagtca tggtgaaaga tgtaaacgaa gaccttatga aaggttacga
      901 tatctttaca ccaatcgctg caacagacct tggttttgaa ccaggtatcc cagttatcga
      961 agctgggcca atcttattc
//
LOCUS       DAVBIC010000106          949 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.106, whole genome shotgun sequence.
ACCESSION   DAVBIC010000106 DAVBIC010000000
VERSION     DAVBIC010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 949)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 949)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..949
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.106"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            <1..>949
                     /locus_tag="VQ664_002107"
     CDS             <1..>949
                     /locus_tag="VQ664_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element ISSpn8 family transposase"
                     /protein_id="HET2790193.1"
                     /translation="QEHYTPKGKHLTIDNRRLIERWKNENKSNREIAGLLGKAPQTIH
                     NEVKRGTTLQQVRKGLYKKVYSADYAQTVYQFNRKRSVKKLILTKEIREKILHYHKQK
                     FSPEMMVNKKQVKVGISTIYYWFHNGHLGLTKADMLYPRKRKGVKKQASPNFKPAGKS
                     IEERPDVINLRLENGHYEIDTVLLTKIKNYCLLVLTDRRSRHQIIRLIPNKTAESVNQ
                     ALTLLLGEHRILSITADNGSEFKRLSEVFPEEHIYYAHAYSSWERGSNENHNRLIRRW
                     LPKGTKKTTPKEVAFIENWINNYPKKCLDYKSPSEFLLGG"
BASE COUNT          336 a          171 c          196 g          246 t
ORIGIN      
        1 caagaacatt ataccccaaa agggaaacat ttgacaatag ataaccgtcg cttgattgag
       61 cggtggaaga atgaaaataa gtccaatcgt gaaattgcag gcttgttagg aaaggcgcct
      121 caaacgattc ataatgaagt caaaagaggt acaactttac aacaagtgag aaaagggcta
      181 tacaaaaagg tctattctgc cgattacgca caaactgttt accaattcaa tcgaaaacgg
      241 tcggtgaaaa agttaatttt aacaaaggaa atcagagaga agatcttaca ctatcataag
      301 caaaaatttt cgcctgaaat gatggttaac aagaagcaag tgaaagttgg tatttcaacc
      361 atctactact ggtttcataa tggtcattta ggattgacga aggccgacat gctttatccc
      421 agaaaaagga aaggtgtcaa gaagcaagct agtccgaact ttaagccggc aggtaaatct
      481 atcgaagaac gtcctgacgt tattaatctt cgcttggaaa atggtcatta tgaaattgat
      541 accgtcctac tgactaagat aaaaaattat tgcctgttag tcttaaccga ccggcggagc
      601 agacaccaaa ttataaggtt aattccaaat aaaactgctg aatctgtcaa tcaggcgctt
      661 acgttactat taggggagca tcgtattctg tccattactg cagataatgg ttcggagttc
      721 aaacgattgt ctgaggtatt tcctgaggaa catatctact acgcacatgc ttactcttca
      781 tgggagagag gttcaaatga aaatcataat cgattaattc ggagatggtt acctaaagga
      841 accaagaaaa cgactccgaa agaagtagct tttatcgaaa attggattaa caactaccct
      901 aaaaaatgct tggactacaa gtcgccaagt gaatttcttt tgggtggct
//
LOCUS       DAVBIC010000107          921 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.107, whole genome shotgun sequence.
ACCESSION   DAVBIC010000107 DAVBIC010000000
VERSION     DAVBIC010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 921)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 921)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..921
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.107"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            complement(189..>921)
                     /gene="phtD"
                     /locus_tag="VQ664_002108"
     CDS             complement(189..>921)
                     /gene="phtD"
                     /locus_tag="VQ664_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtD"
                     /protein_id="HET2790194.1"
                     /translation="NRVKAAKKVPLDRMPYNLQYTVEVKNGSLIIPHYDHYHNIKFEW
                     FDEGLYEAPKGYTLEDLLATVKYYVEHPNERPHSDNGFGNASDHVQRNKNGQADTNQT
                     EKPNEEKPQTEKPEEDKEHDEVSEPTHPESDEKENHAGLNPSADNLYKPSTDTEETEE
                     EAEDTTDEAEIPQVEHSVINAKIAEAEALLEKVTDSSIRQNAVETLTGLKSSLLLGTK
                     DNNTISAEVDSLLALLKESQPTPIQ"
BASE COUNT          235 a          184 c          157 g          345 t
ORIGIN      
        1 gatgaagttt tttctcaact tcttttactt tattaaatag ttttctaaac cggttattta
       61 accatttaat taaccagtaa atagtttact atttaaaatt acttttgtca agtttctgtt
      121 acgtttttct aaaaaagaga agtaacacga aaggttactt ctccataaaa tatgctccat
      181 tcattttact actgtatagg agtcggttga ctttctttta acaaagccaa gagactatct
      241 acttctgctg aaatagtgtt attatctttc gttccgagaa gaagactact ttttagacca
      301 gtcaatgtct ccacagcatt ttgtctaata ctagaatctg ttactttttc tagcaaggcc
      361 tccgcctctg ctatcttagc gttaataaca gaatgctcta cttgaggaat ttcagcctca
      421 tctgtagtat cttcagcttc ttcctctgtc tcttccgtat cagtgcttgg tttataaaga
      481 ttatctgctg aaggatttaa accagcgtga ttctcttttt catcagattc agggtgagtt
      541 ggctcactta cttcatcatg ttccttatct tcctcaggtt tttctgtctg aggtttctcc
      601 tcgtttggtt tttccgtttg attggtatca gcttgaccat ttttgtttct ttgaacatgg
      661 tcgctagcgt taccaaaacc attatctgaa tgcggacgtt cgtttggatg ttcgacatag
      721 tacttgacag tcgccaaaag atcctcaaga gtatacccct taggtgcctc ataaaggcct
      781 tcgtcaaacc actcaaattt gatgttatgg taatggtcat aatgaggtat gattaaacta
      841 ccgtttttga cttctacagt atattgaaga ttgtaaggca tacgatcaag tggcaccttc
      901 ttagctgctt tcacgcggtt g
//
LOCUS       DAVBIC010000108          902 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.108, whole genome shotgun sequence.
ACCESSION   DAVBIC010000108 DAVBIC010000000
VERSION     DAVBIC010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 902)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 902)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..902
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.108"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            122..590
                     /locus_tag="VQ664_002109"
                     /pseudo
     CDS             122..590
                     /locus_tag="VQ664_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817843.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          331 a          135 c          166 g          270 t
ORIGIN      
        1 gagaagagga ttgccatctt ctccattttt atgtgcagag ttatagtggc ttgatgctgg
       61 gaaagtacac tgtgactgct aaaacattcc tagaagctgc tttgatttcc ctaatctatt
      121 tatgcaaatt ttatgttatt ttactataac agttgttgct aagccaaata atagtgggga
      181 agttcattta gacgtaagca ttgaagataa tcagggaggt agtgggtata atttcagttc
      241 tgtttcaagt agctcacaaa cagctaaata tgaaggaact ggttataata acaattcatc
      301 attatatata acgattgata aaacgtctga tgcaacagct cttttgaaat taaagttgaa
      361 taatgttgat aatcaacctg ctactgaagt tcctagttca ggaattactg taaaattaaa
      421 tgctaaagat aatgctggaa actggacaag tgcttcgaat aaagacaagt gcttcgaata
      481 aaaaagaaat aacagtaaaa attgtttctg ctaaaccgac atatccagac aaaatcttag
      541 tgaaaaatcc tgataatata aaagatacag aaaaaaatgc cattattgaa aaattgaaag
      601 aggcaaataa aaatcatcca gcaggagctc caacctttgc taaaggtgaa ggagagcatg
      661 caaatgatat tgtagcaact tattcagatg gtacaactta ttatgtaccg ttaaatgatg
      721 tgacaaaata tgcgaggtag tggctgtacc actcacttat tcacctcccc gtgatttgta
      781 gtagtgatag gctttctcac tattattata aaacaaaata aagatcacaa cactttttca
      841 ttctgtgttg tgccttgagt gaaacgaaag gaatgaatta taaatatgaa aagtatagtc
      901 ac
//
LOCUS       DAVBIC010000109          840 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.109, whole genome shotgun sequence.
ACCESSION   DAVBIC010000109 DAVBIC010000000
VERSION     DAVBIC010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 840)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 840)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..840
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.109"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            1..840
                     /locus_tag="VQ664_002110"
                     /pseudo
     CDS             1..840
                     /locus_tag="VQ664_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
BASE COUNT          255 a          184 c          137 g          264 t
ORIGIN      
        1 ctaaaattcc ttatcttgaa acaactggta tgccttctag aattctcctt agaaaacgcc
       61 gtttcaagtg ctatcactgt tcaaaaatga tggttgctga gactcccctg gtaaagaaaa
      121 atcaccaaat ccctcgtatc atcaaccaaa aaattgctca aaagttaatt gaaaaaattt
      181 ctatgactga tattgctcat cagctggcca tttcaacttc aactgtcatt cgcaagctca
      241 atgactttca ctttgagcat gatttttcgc gtcttcctga gattatgtct tgggatgagt
      301 atgcttttac aaagggaaag atgagcttca ttgcgcaaga ttttaacaat ctcaatatca
      361 tcactgttct tgagggaaga acacaagcta tcattcgaaa tcactttctt aaatatgata
      421 gagccgtccg atgtcgcgtc aaaatcatta ctatggatat gtttagccct tactatgact
      481 tggctaaaca gcttcgcttt caaatttcta ggctcaggct gaaacagtct cccagactgt
      541 ttcactcccg aatgctaaaa tcgttcttga tcgctttcat attgtacaac atcttagccg
      601 tgctatgagt cgtgtgcgtg tccaaatcat gaatcagttt catcgaaaat cccatgaata
      661 caaggctatc aagcgctact ggaaactcat tcaacaggat agccgtaaac tgagtgataa
      721 acgtttttat cgtcctactt ttcgtatgca cttaaccaat aaagagattt taaacaagct
      781 tttgagttat tcggaagact tgaaacacca ctatcaactc tatcaactct tgctttttca
//
LOCUS       DAVBIC010000110          830 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.110, whole genome shotgun sequence.
ACCESSION   DAVBIC010000110 DAVBIC010000000
VERSION     DAVBIC010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 830)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 830)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..830
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.110"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            21..830
                     /locus_tag="VQ664_002111"
                     /pseudo
     CDS             21..830
                     /locus_tag="VQ664_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558050.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5-like element IS1515 family transposase"
BASE COUNT          266 a          174 c          162 g          228 t
ORIGIN      
        1 aaaagtgtta tactattttt atggaaacag tatacgacaa agcacaaaaa cttaactcaa
       61 aaaacttcaa actattgatt ggtgtcaaaa aggaaacctt tcaactcatg ctagaacacc
      121 tgaattcagc ctatcagatt cagcaccgaa aaggtggacg tccacgtagt ctgcccatgg
      181 aagaccagct cattatgacc ctccgttact tgcgatatta tcccactcag cgtctgctgg
      241 cctttgattt tggcgtcggt gtagctacgg taaatgccat catcacttgg gtggaggata
      301 cacttcgtgc gtcaggtagc tttgatttgg accatttaga agccccgagt gctgctgtgg
      361 ctattgacgt gaccgaaagt ccgattcagc gtccaaaaaa aaccaaagca aaaattattc
      421 tggtaaaaag aaacgacaca ccttaaaaac tcaaattatg ctggatttga cgacacataa
      481 agtctgtcaa atggcctttt ctgacggaca tacgcatgat tttactctct tcaaagaaag
      541 tattggacaa agtttgcctg aaacgacgct tgcctttgtt gacctaggtt atttaggcat
      601 cttgaaattt catgagaata ctttcattcc tgctaaaaat tccaaaaatc gccgcctgag
      661 tgaggatgat aagcagttaa ataaagagat gtcagcgata cgaattgaaa ttgaacattt
      721 taacgctaaa ttcaagacct tccaaatcat gtcagtccct tatcgtaacc gcagaaaacg
      781 tttcgagtta cgggcggaat taatttgtgc catcatcaat tatgaagtga
//
LOCUS       DAVBIC010000111          692 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.111, whole genome shotgun sequence.
ACCESSION   DAVBIC010000111 DAVBIC010000000
VERSION     DAVBIC010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 692)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 692)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..692
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.111"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            complement(74..147)
                     /locus_tag="VQ664_002112"
     tRNA            complement(74..147)
                     /locus_tag="VQ664_002112"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(111..113),aa:Arg,seq:acg)
     gene            complement(157..242)
                     /locus_tag="VQ664_002113"
     tRNA            complement(157..242)
                     /locus_tag="VQ664_002113"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(206..208),aa:Leu,seq:taa)
     gene            complement(250..321)
                     /locus_tag="VQ664_002114"
     tRNA            complement(250..321)
                     /locus_tag="VQ664_002114"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(287..289),aa:Gly,seq:gcc)
     gene            complement(344..416)
                     /locus_tag="VQ664_002115"
     tRNA            complement(344..416)
                     /locus_tag="VQ664_002115"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(381..383),aa:Thr,seq:tgt)
     gene            complement(435..516)
                     /locus_tag="VQ664_002116"
     tRNA            complement(435..516)
                     /locus_tag="VQ664_002116"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(480..482),aa:Leu,seq:tag)
     gene            complement(522..594)
                     /locus_tag="VQ664_002117"
     tRNA            complement(522..594)
                     /locus_tag="VQ664_002117"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(559..561),aa:Lys,seq:ttt)
     gene            complement(619..691)
                     /locus_tag="VQ664_002118"
     tRNA            complement(619..691)
                     /locus_tag="VQ664_002118"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(656..658),aa:Asp,seq:gtc)
BASE COUNT          179 a          205 c          149 g          159 t
ORIGIN      
        1 cgaacctgcg acaccttggt cccaaaccaa gtactctacc aagctgagct acttcccgag
       61 ttaaatagaa aaatgcaccc tagaggagtc gaacctctaa ccgcctgatt cgtagtcagg
      121 tactctatcc agttgagcta agggtgctcc atattatgcc gaggaccgga atcgaaccgg
      181 tacgatcgtt accaatcgca ggattttaag tcctgtgcgt ctgccagttc cgccaccccg
      241 gcctctctaa gcgaacgacg ggattcgaac ccgcgacccc caccttggca aggtggtgtt
      301 ctaccactga actacgttcg cactgttttc ttctatctaa aaatgccggc tacatgactt
      361 gaacacgcga ccctctgatt acaaatcaga tgctctacca actgagctaa gccggctcat
      421 ttgttatatc ttaatgcggg ttaagggact tgaaccccca cgccgttaag cgccagatcc
      481 taaatctggt gcgtctgcca attccgccaa acccgcatat atgacccgta ctgggctcga
      541 accagtgacc cattgattaa aagtcaattg ctctaccaac tgagctaacg agtctaaaat
      601 aacttgcgtt accttaaacg gtcccgacgg gaatcgaacc cgcgatcttc gccgtgacag
      661 ggcgacgtga taaccgctac actacgggac ct
//
LOCUS       DAVBIC010000112          690 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.112, whole genome shotgun sequence.
ACCESSION   DAVBIC010000112 DAVBIC010000000
VERSION     DAVBIC010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 690)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 690)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..690
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.112"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            1..686
                     /locus_tag="VQ664_002119"
                     /pseudo
     CDS             1..686
                     /locus_tag="VQ664_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          213 a          151 c          113 g          213 t
ORIGIN      
        1 attactatgg atatgtttag cccttactat gacttagcta gacagcttcg ctttcaaatt
       61 tctaggctca ggctgaaaca gtctcccaga ctgtttcact cccgaatgct aaaatcgttc
      121 ttgatcgctt tcacattgtg caacatctta gccgtgctat gagtcgtgtg cgtgtttaaa
      181 tcatgaatca gtttcatcga aaatcccatg aatacaaggc tatcaagcgc tactggaagc
      241 tcatacaaca ggatagccgt aaactgagtg ataagcgttt ttatcgtcct acttttcgta
      301 tgcatttaac caataaagag attttagaca agcttttgag ctattcggaa gacttgaaac
      361 accactatca gctctatcag ctcttgcttt ttcacttcca gaataaggaa ccagagaaat
      421 ttttcggact tattgaggac aatctgaagc aggttcatcc tatttttcag actgtcttta
      481 aaaccttcct caaagataaa gaaaagatta tcaacgccct tcaactaccc tattcaaacg
      541 ccaaattgga agcgaccaat aatctcatca aacttatcaa gcacaatgcc tttggttttc
      601 ggaactttga aaacttcaaa aaacggattt ttatcgctct gaatatcaaa aaagaaagga
      661 cgaaatttgt cctttctcga tcttagcttt
//
LOCUS       DAVBIC010000113          671 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.113, whole genome shotgun sequence.
ACCESSION   DAVBIC010000113 DAVBIC010000000
VERSION     DAVBIC010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 671)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 671)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..671
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.113"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            <1..>671
                     /locus_tag="VQ664_002120"
     CDS             <1..>671
                     /locus_tag="VQ664_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HET2790195.1"
                     /translation="HVESDGLVFDPAQITSRTARGVAVPHGNHYHFIPYEQMSELEKR
                     IARIIPLRYRSNHWVPDSRPEQPSPQSTPEPSPSLQPAPNPQPAPSNPIDEKLVKEAV
                     RKVGDGYVFEENGVSRYIPAKDLSAETAAGIDSKLAKQESLSHKLGAKKTDLPSSDRE
                     FYNKTYDLLARIHQDLLDNKGRQVDFEALDNLLERLKDVSSDKVKLVDDILAFLAPIR
                     HPERLG"
BASE COUNT          210 a          148 c          137 g          176 t
ORIGIN      
        1 catgtagaat ctgatggcct tgttttcgac ccagcgcaaa tcacaagtcg aaccgccaga
       61 ggtgtagctg tccctcatgg taaccattac cactttatcc cttatgaaca aatgtctgaa
      121 ttggaaaaac gaattgctcg tattattccc cttcgttatc gttcaaacca ttgggtacca
      181 gattcaagac cagaacaacc aagtccacaa tcgactccgg aacctagtcc aagtctgcaa
      241 cctgcaccaa atcctcaacc agctccaagc aatccaattg atgagaaatt ggtcaaagaa
      301 gctgttcgaa aagtaggcga tggttatgtc tttgaggaga atggagtttc tcgttatatc
      361 ccagccaagg atctttcagc agaaacagca gcaggcattg atagcaaact ggccaagcag
      421 gaaagtttat cgcataagct aggagctaag aaaactgacc tcccatctag tgatagagaa
      481 ttttacaata agacttatga cttactagca agaattcacc aagatttact tgataataaa
      541 ggtcgacaag ttgattttga ggctttggat aacctgttgg aacgactcaa ggatgtctca
      601 agtgataaag tcaagttagt ggatgatatt cttgccttct tagctccgat tcgtcatcca
      661 gaacgtttag g
//
LOCUS       DAVBIC010000114          633 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.114, whole genome shotgun sequence.
ACCESSION   DAVBIC010000114 DAVBIC010000000
VERSION     DAVBIC010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 633)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 633)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..633
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.114"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
BASE COUNT          196 a          121 c          161 g          155 t
ORIGIN      
        1 tttaggctga ttttaagtac gacgggcatg tcgtgcatct gaggtgtaag tcctccgtgg
       61 gcacctgcta ccggtgaacc caatagcgat tcccaagcct gactatcgtg aggtagcgga
      121 ttaaaacggt ctggggatag accgttttaa gtctgacgca ggaaataaga atcgtcagag
      181 gaagggatag cgaaatcgag gctctacgaa caggaacgtg atagtaaggc gtatacagcg
      241 gataaggggg cttaaaactc taaagtccaa aaaggtagtc gtaacctata tgcgtaaatc
      301 acgagagtaa ttgaattcgg actaaggtct atgtgaaaaa gataaatctt cctagagtct
      361 aaagactctg cgtcagattt cctattttca ttgtaacctt ttaacgtcct catatcttgt
      421 ataaacgagg aaagatgtac ggcttatccc gtgaggtctc atgagcgccg aaagcgtagt
      481 aacaacgaat catgagaagt cagccgagcc catagtagtg aggaaacttc tgtaatggaa
      541 gtggagcgaa ggggtaaaca actaatcgaa gtaatcctac ttcacttgtg tctgtaaaac
      601 gaacggtctg atagaactgg actctgtcac gta
//
LOCUS       DAVBIC010000115          592 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.115, whole genome shotgun sequence.
ACCESSION   DAVBIC010000115 DAVBIC010000000
VERSION     DAVBIC010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 592)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 592)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..592
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.115"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            complement(<1..>592)
                     /locus_tag="VQ664_002121"
     CDS             complement(<1..>592)
                     /locus_tag="VQ664_002121"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2790196.1"
                     /translation="ADALVLAEADALVLAEADALVDADSEADVLAEAEALVDAEAEAL
                     VEAEADALVDAEADALVLAEAEALVDAEAEALVLAEAEALVDAEAEALVDAEADALVD
                     AEAEALVDAEAEADVDADSDALVLAEAEALVLAEADALVEADSDALVEAEADALVDAE
                     AEALVDAEAEALVDAEAEALVLAEAEALVDADAEALV"
BASE COUNT          135 a          196 c          142 g          119 t
ORIGIN      
        1 gtactagcgc ctcagcatca gcgtcaacca gtgcttcggc ttcagcaagt actagtgcct
       61 cagcctcagc atcaacaagc gcctcagctt cagcgtcaac cagtgcctcg gcttcagcat
      121 caacgagtgc gtcagcttca gcctcaacga gtgcgtctga gtcagcctca acgagtgcgt
      181 cggcttcagc aagtaccagt gcttcggcct cagcaagcac aagtgcgtct gaatccgcat
      241 caacgtctgc ctcagcctca gcatcgacaa gcgcttcagc ttcagcgtcg acaagtgcgt
      301 cagcctcagc atcgacaagc gcttcagctt cagcgtcgac aagtgcttcg gcttcagcaa
      361 gcaccagtgc ctcggcttca gcgtcgacaa gtgcctcagc ttcagcaagt accagtgcgt
      421 cagcctcagc atcaacgagt gcgtcggctt cagcctcaac gagtgcttca gcttcagcat
      481 caacgagtgc ttcggcttca gcaagcacat cagcttctga atcagcatca accagtgcat
      541 cagcctcagc aagcaccagt gcgtcggctt cagcaagtac cagtgcgtca gc
//
LOCUS       DAVBIC010000116          557 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.116, whole genome shotgun sequence.
ACCESSION   DAVBIC010000116 DAVBIC010000000
VERSION     DAVBIC010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 557)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 557)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..557
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.116"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            complement(<1..>557)
                     /locus_tag="VQ664_002122"
     CDS             complement(<1..>557)
                     /locus_tag="VQ664_002122"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2790197.1"
                     /translation="AEALVEADSDALVEADSDAEVLAEAEALVDAEAEALVLAEADAL
                     VLAEAEALVDADSDAEVLAEAEALVLAEADALVDAEAEALVDAEAEALVDADSEADVL
                     AEAEALVDADSDALVDAEAEALVDADAEALVLAEADALVLAEAEALVDAEAEALVLAE
                     ADALVEAEADALVDAEAEALVLAEA"
BASE COUNT          137 a          183 c          124 g          113 t
ORIGIN      
        1 tcagcttcag caagcaccag tgcttcagct tcagcatcaa caagtgcatc agcttcggcc
       61 tcaacaagtg cgtcagcttc agcaagcacc agtgcttcgg cttcagcgtc gacaagtgcc
      121 tcagcttcag caagtaccag tgcgtcagcc tcagcaagta ctagcgcctc agcatcagcg
      181 tcaacaagtg cttcggcttc agcgtcaacg agtgcgtctg agtcagcatc aacgagtgct
      241 tcagcctcag caagcacatc agcttctgaa tccgcatcaa caagtgcttc agcctcagcg
      301 tcaacaagtg cttcagcttc agcatcaacc agtgcatcag cttcagcaag tactagcgcc
      361 tcagcttcag caagcacctc agcgtctgaa tcggcatcaa cgagcgcctc agcttcagca
      421 agtaccagtg cgtcagcctc agcaagtacc agtgcttcag cctcagcgtc gacaagtgcc
      481 tcggcttcag caagtacctc agcgtctgaa tcggcctcaa ccagtgcatc tgaatcggcc
      541 tcaaccagtg cctcagc
//
LOCUS       DAVBIC010000117          545 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.117, whole genome shotgun sequence.
ACCESSION   DAVBIC010000117 DAVBIC010000000
VERSION     DAVBIC010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 545)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 545)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..545
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.117"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            complement(<1..>545)
                     /locus_tag="VQ664_002123"
     CDS             complement(<1..>545)
                     /locus_tag="VQ664_002123"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2790198.1"
                     /translation="AEALVDAEADALVEADSEAEVLAEADALVDAEADALVLAEADAL
                     VDAEADALVLAEAEALVDAEADALVLAEAEALVDAEADALVLAEAEALVDAEAEALVD
                     ADSEALVDAEADALIDADSEADVLAEAEALVDAEAEALVDADSEALVDAEAEADVDAE
                     ADALVDAEADALVDAEAEALV"
BASE COUNT          129 a          180 c          125 g          111 t
ORIGIN      
        1 tcaaccagcg cctcagcttc agcatcaacg agtgcgtcgg cttcagcatc aacgagtgca
       61 tcggcttcag catcaacgtc tgcctcagct tcagcgtcaa ccagtgcctc tgaatcggca
      121 tcaaccagtg cttcagcctc agcatcgaca agcgcttcgg cttcagcaag tacatcagct
      181 tctgaatctg catcaataag tgcgtcggct tcagcgtcaa ccagtgcctc tgaatcggca
      241 tcaaccagtg cttcagcctc agcatcaacg agtgcttcgg cttcagcaag cacaagtgcg
      301 tcagcttcag cgtcaacgag tgcctcggct tcagcaagca ccagtgcgtc agcttcagca
      361 tcaacgagtg cctcggcctc agcaagtaca agtgcgtcag cctcagcatc aaccagtgca
      421 tcagcctcag caagtaccag tgcatcagct tccgcatcaa cgagtgcatc agcctcagca
      481 agcacctcag cttctgaatc ggcctcaacg agtgcgtcag cctcagcgtc aacgagtgct
      541 tcggc
//
LOCUS       DAVBIC010000118          499 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.118, whole genome shotgun sequence.
ACCESSION   DAVBIC010000118 DAVBIC010000000
VERSION     DAVBIC010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 499)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 499)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..499
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.118"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            complement(<1..>499)
                     /locus_tag="VQ664_002124"
     CDS             complement(<1..>499)
                     /locus_tag="VQ664_002124"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2790199.1"
                     /translation="VLAEAEALVEAEADALVEADSDALVLAEADALVDADSEALVLAE
                     ADALVDAEAEALVLAEADALVLAETEALVLAEAEALVDAEAEALVLAEAEALVDADSD
                     AEVLAEAEALVDAEAEALVLAEAEALVLADSDALVDAEAEALVDAEAEALVDAEAEAL
                     VLAEA"
BASE COUNT          127 a          168 c          109 g           95 t
ORIGIN      
        1 tcagcttcag caagcaccag tgcttcagct tcagcatcaa caagtgcctc agcctcagcg
       61 tcgacaagtg cctcggcttc agcatcgaca agtgcatctg aatcagcaag cacaagtgct
      121 tcagcttcag caagtaccag cgcctcagcc tcagcatcaa ccagtgcttc ggcttcagca
      181 agtacctcag cgtctgaatc ggcatcaaca agtgcttcag cttcagcaag tacaagcgcc
      241 tcagcttcag catcaaccag tgcttcggct tcagcaagca ccagtgcctc agtctcagca
      301 agcaccagtg cgtcggcttc agcaagcaca agcgcctcag cttcagcatc aaccagtgcg
      361 tcagcctcag caagtaccag tgcctctgaa tccgcatcaa caagtgcatc ggcttcagca
      421 agcaccagtg cgtctgagtc agcctcaacg agtgcgtcgg cttcagcctc aaccagcgcc
      481 tcagcctcag caagtacaa
//
LOCUS       DAVBIC010000119          497 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.119, whole genome shotgun sequence.
ACCESSION   DAVBIC010000119 DAVBIC010000000
VERSION     DAVBIC010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 497)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 497)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..497
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.119"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            complement(1..497)
                     /locus_tag="VQ664_002125"
                     /pseudo
     CDS             complement(1..497)
                     /locus_tag="VQ664_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          157 a          100 c           96 g          144 t
ORIGIN      
        1 taaaatctct ttattggtta aatgcatacg aaaagtaggg cgataaaaat gtttatcgct
       61 gagtttacga ctatcctgtt gtatgagctt ccagtagcgc ttgatagcct tgtattcatg
      121 agactttcga tccaattgat tcatgatttg aacacgcaca cgactcatag cacggctaag
      181 atgttgtaca atgtgaaagc gatccaacac gattttagca catgggaaaa gttgtctagc
      241 taagtcatag taaggactaa acatatccat agtaataatt ttgacgcgac atcggacggc
      301 tctatcatat ttaagaaagt gatctcggat gacagcttgt gttctaccct caagaacagt
      361 gatgatattg agattgttaa aatcttgcgc aatgaagctc atctccatct cccgattgaa
      421 acagtcactc cccggactgt ttcaacgtcc caagacataa tctcaggcag atttctaaaa
      481 ttacactcaa agtggaa
//
LOCUS       DAVBIC010000120          393 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.120, whole genome shotgun sequence.
ACCESSION   DAVBIC010000120 DAVBIC010000000
VERSION     DAVBIC010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 393)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 393)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..393
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.120"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            <1..>393
                     /locus_tag="VQ664_002126"
     CDS             <1..>393
                     /locus_tag="VQ664_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HET2790200.1"
                     /translation="YLHLWELSDWDQEGMLCLHELISREEGLVDDIPRLRKYFKTKFR
                     NRILDYIRKQESQKRRYDKEPYEEVGEISHRISEGGLWLDDYYLFHETLRDYRNKQSK
                     EKQEELERVLSNERFRGRQRVLRDLRIVF"
BASE COUNT          143 a           57 c           93 g          100 t
ORIGIN      
        1 taccttcatt tatgggaatt gtcggattgg gaccaagaag gcatgctctg cttacatgaa
       61 ttgattagta gagaagaagg actggtagac gatattccac gtttaaggaa atatttcaaa
      121 accaagtttc gaaatcgaat tttagactat atccgtaagc aggaaagtca gaagcgtaga
      181 tacgataaag aaccctatga agaagtggga gagatcagtc atcgtataag tgaggggggt
      241 ctctggctag atgattatta tctctttcat gaaacactaa gagattatag aaacaaacaa
      301 agtaaagaga aacaagaaga actagaacgc gtcttaagca atgaacgatt tcgagggcgt
      361 caaagagtat taagagactt acgcattgtg ttt
//
LOCUS       DAVBIC010000121          310 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.121, whole genome shotgun sequence.
ACCESSION   DAVBIC010000121 DAVBIC010000000
VERSION     DAVBIC010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 310)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 310)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..310
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.121"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            complement(163..236)
                     /locus_tag="VQ664_002127"
     tRNA            complement(163..236)
                     /locus_tag="VQ664_002127"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(200..202),aa:Asn,seq:gtt)
BASE COUNT          102 a           71 c           48 g           89 t
ORIGIN      
        1 ctgttcgctc acaataagag agaacttttt tacgaaaatc tattgaatat gccataaaaa
       61 gattatacca cattgtgtac tatttttggt tcattttact ataacacgaa atagattatt
      121 attacataac aaaaaagagg tctaaacctc ttaactaaat tactccgcca gtaggactcg
      181 aacctacgac atcatgatta acagtcatgc gctactacca actgagctat ggcggattaa
      241 agctaagcga cttccctatc tcacaggggg caacccccaa ctacttccgg cgttctaggg
      301 cttaacttct
//
LOCUS       DAVBIC010000122          292 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.122, whole genome shotgun sequence.
ACCESSION   DAVBIC010000122 DAVBIC010000000
VERSION     DAVBIC010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 292)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 292)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..292
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.122"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            51..>292
                     /locus_tag="VQ664_002128"
     rRNA            51..>292
                     /locus_tag="VQ664_002128"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT           90 a           54 c           81 g           67 t
ORIGIN      
        1 gaaaaaaaca ataaatctgt cagtgacaga aatgagtgag aactcaaact tttaatgaga
       61 gtttgatcct ggctcaggac gaacgctggc ggcgtgccta atacatgcaa gtagaacgct
      121 gaaggaggag cttgcttctc tggatgagtt gcgaacgggt gagtaacgcg taggtaacct
      181 gcctggtagc gggggataac tattggaaac gatagctaat accgcataag agtagatgtt
      241 gcatgacatt tgcttaaaag gtgcacttgc atcactacca gatggacctg cg
//
LOCUS       DAVBIC010000123          277 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.123, whole genome shotgun sequence.
ACCESSION   DAVBIC010000123 DAVBIC010000000
VERSION     DAVBIC010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 277)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 277)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..277
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.123"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            <1..>277
                     /locus_tag="VQ664_002129"
     CDS             <1..>277
                     /locus_tag="VQ664_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET2790201.1"
                     /translation="QRIIEAIESALEKVDEYAESYNRLEQLDKEFPDKLKKSILQYAM
                     QGKLVEQDPNDESVEVLLEKIRAEKQKLFEEGKIKKKDLDISIVSQG"
BASE COUNT          126 a           37 c           47 g           67 t
ORIGIN      
        1 aacaacgcat aatagaagca atcgaatcag ctttagaaaa agtagatgaa tatgctgaaa
       61 gttataatag actagaacag ctagataaag aatttccaga taaactaaaa aaatctattc
      121 ttcaatatgc tatgcaagga aaattagttg aacaagaccc aaatgatgaa tcagtcgaag
      181 ttttacttga aaaaatacga gcagaaaaac aaaaactctt tgaagaaggc aagattaaaa
      241 agaaagattt ggacatttct attgtttccc aaggaga
//
LOCUS       DAVBIC010000124          272 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 1610212907
            SAMEA1678035-rid20177793.denovo.124, whole genome shotgun sequence.
ACCESSION   DAVBIC010000124 DAVBIC010000000
VERSION     DAVBIC010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1678035
            Sequence Read Archive: ERR223006
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 272)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 272)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980109.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980109.1
            Genome Coverage       :: 88x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 03:21:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,130
            CDSs (total)                      :: 2,090
            Genes (coding)                    :: 1,946
            CDSs (with protein)               :: 1,946
            Genes (RNA)                       :: 40
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 34
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 144
            CDSs (without protein)            :: 144
            Pseudo Genes (ambiguous residues) :: 0 of 144
            Pseudo Genes (frameshifted)       :: 68 of 144
            Pseudo Genes (incomplete)         :: 70 of 144
            Pseudo Genes (internal stop)      :: 38 of 144
            Pseudo Genes (multiple problems)  :: 28 of 144
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..272
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1678035-rid20177793.denovo.124"
                     /strain="1610212907"
                     /db_xref="taxon:1313"
     gene            complement(1..272)
                     /locus_tag="VQ664_002130"
                     /pseudo
     CDS             complement(1..272)
                     /locus_tag="VQ664_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="internal stop; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT           85 a           43 c           57 g           87 t
ORIGIN      
        1 ttctggaaat gaaaaagcaa gagctgatag agttgatagt ggtgtttcaa gtcttccgaa
       61 taactcaaaa gcttgtttaa aatctcttta ttggttcaat gcatacgaaa agtaggacga
      121 taaaaatgtt tatcactcag tttacgacta tcctgttgaa tgagtttcca gtagcgcttg
      181 atagccttgt attcatggga ttttcgatga aactgattta tgatttgaac acgcacacga
      241 ctcatagcac ggctaagatg ttgtacaatg tg
//
